Reference : Babesia divergens: activité de l'oxytétracycline retard chez la gerbille, Meriones un...
Scientific journals : Article
Life sciences : Veterinary medicine & animal health
Babesia divergens: activité de l'oxytétracycline retard chez la gerbille, Meriones unguiculatus
[en] Babesia Divergens: Activity of Long-Acting Oxytetracycline in the Gerbil, Meriones Unguiculatus
Losson, Bertrand mailto [Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Parasitologie et pathologie des maladies parasitaires >]
Patz, R. [> > > >]
Annales de Recherches Vétérinaires = Annals of Veterinary Research
[en] The authors studied the prophylactic activity of long-acting oxytetracycline in the gerbil, Meriones unguiculatus, infected with the cattle piroplasm Babesia divergens. Parasitemia, packed cell volume (PCV) and survival rate were monitored. At 5 and 20 mg/kg, the prophylactic activity was absent and all the animals died. At 40 mg/kg, two animals out of five survived but were clinically affected and sustained a severe hemolytic anaemia. However, at 80 mg/kg, the parasitemias remained very low, the PCV's were unchanged and all the animals survived; furthermore, they were totally resistant to a challenge infection given 33 days after the primary infection. There is a good agreement between these results and those reported in cattle naturally or experimentally infected with B. divergens.

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