[en] Naturally occurring sleep and altered consciousness related to the infusion of sedative medications are sometimes mistakenly thought of as being equivalent. While similarities between these two states do exist, differences are considerable and clinically important. Normal sleep is characterized by a cyclic, organized series of brain activities with clearly defined stages that is governed by circadian and homeostatic forces and responsive to external stimuli where arousal leads to almost immediate patient awareness. Consciousness altered by sedative medications has few, if any, of these characteristics. The unique effects of sleep and altered consciousness related to sedative use on brain activity can be described by both phenomenological and physiological parameters. This chapter will review the similarities and differences between natural sleep and sedative-associated alterations in consciousness to determine whether the essential physiologic functions of sleep, some of which may be important to recovery from critical illness, also occur during sedative infusion administration.
Disciplines :
Anesthesia & intensive care
Author, co-author :
BECK, Florian ; Centre Hospitalier Universitaire de Liège - CHU > Département d'Anesthésie et réanimation > Service d'anesthésie - réanimation
Gosseries, Olivia ; Université de Liège - ULiège > GIGA Consciousness - Coma Science Group
Weinhouse, Gerald; Harvard University > Division of Pulmonary and Critical Care
BONHOMME, Vincent ; Centre Hospitalier Universitaire de Liège - CHU > Département d'Anesthésie et réanimation > Service d'anesthésie - réanimation
Language :
English
Title :
Normal Sleep Compared to Altered Consciousness During Sedation
Publication date :
2022
Main work title :
Sleep in Critical Illness: Physiology, Associated Outcomes, and its Potential Role in Recovery
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