Cardiac Performance in Conscious Healthy Dogs During Dobutamine Infusion

Mc Entee, Kathleen; Clercx, Cécile; Pypendop, B.; Peeters, Dominique; Balligand, Marc; D'Orio, Vincenzo; Henroteaux, Marc

doi:10.1016/S0034-5288(96)90070-3

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Cardiac Performance in Conscious Healthy Dogs During Dobutamine Infusion

Mc Entee, Kathleen; Clercx, Cécile; Pypendop, B. et al.

1996 • In Research in Veterinary Science, 61 (3), p. 234-9

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10.1016/S0034-5288(96)90070-3

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Abstract :

[en] The aim of this study was to determine the cardiac performance of conscious healthy dogs during stimulation with dobutamine. Eight healthy unsedated beagle dogs were used. Cardiac output was measured by the thermodilution technique and blood pressures by extravascular pressure transducers. Dobutamine challenge at a dosage ranging from 27.5 to 50 micrograms kg-1 min-1 induced a significant rise in cardiac power index (CPI), cardiac index (CI), stroke index (SI) and heart rate (HR) and a significant decrease in pulmonary vascular resistance (PVR) and systemic vascular resistance (SVR). The highest CPI was 2.05 times greater than its basal resting value. The CI was primarily responsible for this increase in CPI. The SI and HR contributed approximately 55 per cent and 45 per cent respectively of the maximal increase in CI.

Disciplines :

General & internal medicine

Author, co-author :

Mc Entee, Kathleen ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Sémiologie et clinique médicale des petits animaux

Clercx, Cécile ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Pathologie médicale des petits animaux

Pypendop, B.

Peeters, Dominique ; Université de Liège - ULiège > Clinique des petits animaux

Balligand, Marc ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Chirurgie et clinique chirurgicale des petits animaux

D'Orio, Vincenzo ; Université de Liège - ULiège > Département des sciences cliniques > Médecine d'urgence - bioch. et phys. hum. normales et path.

Henroteaux, Marc ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Département clinique des animaux de compagnie et des équidés

Language :

English

Title :

Cardiac Performance in Conscious Healthy Dogs During Dobutamine Infusion

Publication date :

November 1996

Journal title :

Research in Veterinary Science

ISSN :

0034-5288

eISSN :

1532-2661

Publisher :

W. B. Saunders Co., United Kingdom

Volume :

Issue :

Pages :

234-9

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 26 October 2009

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