[en] The aim of this study was to determine the cardiac performance of conscious healthy dogs during stimulation with dobutamine. Eight healthy unsedated beagle dogs were used. Cardiac output was measured by the thermodilution technique and blood pressures by extravascular pressure transducers. Dobutamine challenge at a dosage ranging from 27.5 to 50 micrograms kg-1 min-1 induced a significant rise in cardiac power index (CPI), cardiac index (CI), stroke index (SI) and heart rate (HR) and a significant decrease in pulmonary vascular resistance (PVR) and systemic vascular resistance (SVR). The highest CPI was 2.05 times greater than its basal resting value. The CI was primarily responsible for this increase in CPI. The SI and HR contributed approximately 55 per cent and 45 per cent respectively of the maximal increase in CI.
Disciplines :
General & internal medicine
Author, co-author :
Mc Entee, Kathleen ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Sémiologie et clinique médicale des petits animaux
Clercx, Cécile ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Pathologie médicale des petits animaux
Pypendop, B.
Peeters, Dominique ; Université de Liège - ULiège > Clinique des petits animaux
Balligand, Marc ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Chirurgie et clinique chirurgicale des petits animaux
D'Orio, Vincenzo ; Université de Liège - ULiège > Département des sciences cliniques > Médecine d'urgence - bioch. et phys. hum. normales et path.
Henroteaux, Marc ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Département clinique des animaux de compagnie et des équidés
Language :
English
Title :
Cardiac Performance in Conscious Healthy Dogs During Dobutamine Infusion
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