[en] The present invention relates to a compound comprising one or more PEG moieties , wherein said compound is a therapeutic agent active for treating a respiratory disease . The present invention also relates to a method for preventing and / or treating a respiratory disease in a subject in need thereof comprising the administration of a PEGylated therapeutic agent. Another object of the invention is a method for enhancing the bioavailability of a therapeutic agent , for enhancing the pulmonary residency of a therapeutic agent and / or for reducing the pulmonary clearance of a therapeutic agent , wherein said methods comprise the PEGylation of the therapeutic agent .
Disciplines :
Cardiovascular & respiratory systems
Inventor :
Vanbever, Rita
Koussoroplis, Salome
Cataldo, Didier ; Université de Liège - ULiège > Département des sciences cliniques > Labo de biologie des tumeurs et du développement
Van Snick, Jacques
Language :
English
Title (54) :
Method for increasing the bioavailability of inhaled compounds
