No full text
Article (Scientific journals)
Polyploid megakaryocytes develop randomly from a multicompartmental system of committed progenitors
Paulus, Jean-Michel; Prenant, Michel; Deschamps, Jeanne-Françoise et al.
1982In Proceedings of the National Academy of Sciences of the United States of America, 79, p. 4410-4414
Peer Reviewed verified by ORBi
 

Files


Full Text
No document available.

Send to



Details



Keywords :
Hemopoiesis; Megakaryocytes; Polyploidy
Abstract :
[en] In the plasma clot culture system used, megakaryocyte progenitors that do not switch to polyploidization mature through three consecutive compartments, with an increasing probability of becoming polyploid which reflects their fraction ceasing to proliferate
Research center :
Institut de Pathologie Cellulaire, INSERM INSERM U48, Hopital de Bicêtre, 94270 Kremlin-Bicêtre, France
Disciplines :
Hematology
Author, co-author :
Paulus, Jean-Michel ;  Institut de Pathologie Cellulaire, INSERM U48, Hôpital de Bicêtre, 94270 Kremlin-Bicêtre, France
Prenant, Michel;  Institut de Pathologie Cellulaire, INSERM U48, Hôpital de Bicêtre, 94270 Kremlin-Bicêtre, France
Deschamps, Jeanne-Françoise;  Unité de Recherche sur la Thrombose Expérimentale et l'Hémostase, INSERM U150, Hôpital La Riboisière, 74475, Paris Cedex 10, France > INSERM U150, Hôpital Lariboisière, 74475, Paris Cedex 10, France
Henry-Amar, Michel;  Unité de Recherche Statistique, INSERM U21, 16bis Avenue Paul Vaillant-Couturier, 94800 Villejuif, France
Language :
English
Title :
Polyploid megakaryocytes develop randomly from a multicompartmental system of committed progenitors
Publication date :
July 1982
Journal title :
Proceedings of the National Academy of Sciences of the United States of America
ISSN :
0027-8424
eISSN :
1091-6490
Publisher :
National Academy of Sciences, Washington, United States - District of Columbia
Volume :
79
Pages :
4410-4414
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
INSERM - Institut National de la Santé et de la Recherche Médicale [FR]
Centre hospitalier universitaire Kremlin-Bicêtre [FR]
Commentary :
Later studies showed that the increasing probabilty to polyploidize was related to a major increase in progenitor sensitivity to erythropoietin (Blood 104:2291-2298, 2004)
Available on ORBi :
since 23 January 2016

Statistics


Number of views
34 (2 by ULiège)
Number of downloads
0 (0 by ULiège)

Scopus citations®
 
31
Scopus citations®
without self-citations
27
OpenCitations
 
26

Bibliography


Similar publications



Contact ORBi