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Feedback loops: From cellular to network principles
Dethier, Julie
2015
 

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Abstract :
[en] Biological rhythms play a major role in the functioning of the brain. However, the generation mechanisms and functions of these rhythms are still under debate and the question of which cellular details must be retained at the network level is largely open. In this presentation, I will highlight that cellular properties have a major impact at the network level, especially in the study of modulation and robustness. I will focus on a particular cellular property, a positive feedback loop in a specific timescale, and illustrate its network level impact with two simple examples: the modulation and robustness of an half-center oscillator, a very simple central pattern generator composed of two reciprocal-inhibitory populations, and the control of transient beta-band oscillations in the basal ganglia, a group of subcortical nuclei that act as a cohesive functional unit, in relation to motor movements.
Disciplines :
Engineering, computing & technology: Multidisciplinary, general & others
Author, co-author :
Dethier, Julie ;  Université de Liège - ULiège > Dép. d'électric., électron. et informat. (Inst.Montefiore) > Systèmes et modélisation
Language :
English
Title :
Feedback loops: From cellular to network principles
Publication date :
12 January 2015
Event name :
Computational Neuroscience Journal Club
Event organizer :
Brandeis University
Event place :
Waltham, United States
Event date :
21 January 2015
Audience :
International
Available on ORBi :
since 13 January 2015

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