Reference : Analysis of the interactions of natural elicitor rhamnolipids with plant plasma membr...
Scientific congresses and symposiums : Poster
Life sciences : Biochemistry, biophysics & molecular biology
http://hdl.handle.net/2268/173636
Analysis of the interactions of natural elicitor rhamnolipids with plant plasma membranes by in silico methods
English
Polo Lozano, Damien mailto [Université de Liège - ULiège > Chimie et bio-industries > Chimie générale et organique >]
Nasir, Mehmet Nail mailto [Université de Liège - ULiège > Chimie et bio-industries > Chimie générale et organique >]
Deleu, Magali mailto [Université de Liège - ULiège > Chimie et bio-industries > Chimie biologique industrielle >]
Jijakli, Haissam mailto [Université de Liège - ULiège > Sciences agronomiques > Phytopathologie >]
Fauconnier, Marie-Laure mailto [Université de Liège - ULiège > Chimie et bio-industries > Chimie générale et organique >]
Lins, Laurence mailto [Université de Liège - ULiège > Chimie et bio-industries > Biophysique moléc. numér. >]
20-Oct-2014
Yes
National
Biophysics Conference - Modern Biophysical Techniques for the Life Sciences
20 et 21 octobre 2014
Bruxelles
Belgique
[en] Rhamnolipids are surface active molecules produced mainly by various strains of the bacterium Pseudomonas aeruginosa. These secondary metabolites are composed of one to three fatty acids with various chain lengths linked through a glycosidic bond to one or two rhamnose moieties. The fatty acids are linked together through an ester bond. These molecules have shown several biological activities including plant defense stimulation. It has be suggested that this elicitor activity could be related to an interaction of rhamnolipids with the lipid bilayer of the plant plasma membrane (PPM) and lead to its destabilization, which can activate the plant defense signaling pathways. In this context, interactions of two rhamnolipids (Rha-C10-C10 and Rha-Rha-C10-C10) with membrane models and lipidic constituents of the PPM were investigated using in silico approaches. Most probable chemical structures of the rhamnolipids were determined using the STRUCTURE TREE procedure according to the molecule potential energy. The ability of these rhamnolipid structures to insert within the PPM was assessed using IMPALA simulations. IMPALA uses a membrane model in which phospholipids molecules are implicitly modeled by an empirical function and the membrane properties are modeled by energetic restraints. The ability of each rhamnolipid structure to form an assembly with several PPM constituents (phospholipid (PLPC), sterols (Sitosterol, Stigmasterol, Campesterol) and sphingolipids (GIPC, Glucosylceramide)) was calculated using the HYPERMATRIX procedure, which calculate and minimize the energies of interaction between all molecules of the complex until the lowest energy structure is reached.
FIELD (Finding Interesting Elicitor LipiDs)
Researchers
http://hdl.handle.net/2268/173636

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