[en] The effects of a single oral dose of 40 mg propranolol on endurance time and on the maximum oxygen consumption were studied in eight healthy young men. They were running on a motor-driven treadmill (work rate from 80 to 150% VO2 max. The VO2 max and endurance time were decreased to an average of 10 and 30% of controls respectively. The relationship between the endurance time and the relative work load (VO2/VO2 max) remained unchanged after beta-adrenoceptor blockade. The reduction of the endurance time following beta-adrenoceptor blockade is a consequence of the reduction of the VO2 max.
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Camus, G.
Scheen, André ; Université de Liège - ULiège > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques - Médecine interne générale
Cession-Fossion, A.
Juchmes, J.
Mylle, P.
Dreezen, E.
Language :
French
Title :
Endurance apres propranolol chez l'homme effectuant un exercice dynamique general.
Alternative titles :
[fr] Endurance after propranolol in the human execution of a general dynamic exercise
Publication date :
1980
Journal title :
Comptes Rendus des Séances de la Société de Biologie et de ses Filiales