The use of acarbose in the prevention and treatment of hypoglycaemia.

Lefebvre, Pierre; Scheen, André

doi:10.1111/j.1365-2362.1994.tb02255.x

No full text

Article (Scientific journals)

The use of acarbose in the prevention and treatment of hypoglycaemia.

Lefebvre, Pierre; Scheen, André

1994 • In European Journal of Clinical Investigation, 24 Suppl 3, p. 40-4

Peer Reviewed verified by ORBi

Permalink
https://hdl.handle.net/2268/14005

DOI
10.1111/j.1365-2362.1994.tb02255.x

PubMed
8001627

Files (0)Send to Details Statistics Bibliography Similar publications

Files

Full Text

No document available.

Send to

RIS BibTex APA Chicago Permalink X Linkedin

Details

Keywords :

Acarbose; Blood Glucose/metabolism; Diabetes Mellitus, Type 1/blood/drug therapy; Diabetes Mellitus, Type 2/blood/drug therapy; Eating; Humans; Hypoglycemia/drug therapy/prevention & control; Hypoglycemic Agents/therapeutic use; Sulfonylurea Compounds/therapeutic use; Trisaccharides/pharmacology/therapeutic use; alpha-Glucosidases/antagonists & inhibitors

Abstract :

[en] This paper reviews the use of acarbose in the prevention and treatment of hypoglycaemia. In diet- or sulfonylurea-treated patients, acarbose may reduce the incidence of late postprandial hypoglycaemia. In insulin-treated patients, acarbose treatment usually requires reduction of the insulin dose; one study has shown that 100 mg acarbose at night significantly reduces the incidence of mid-evening and nocturnal hypoglycaemia. Several studies have suggested acarbose to be a useful adjunct to the management of reactive hypoglycaemia in the non-diabetic patients. Long-term prospective studies are still needed to document this last indication of acarbose or other alpha-glycosidase inhibitors.

Disciplines :

Endocrinology, metabolism & nutrition

Author, co-author :

Lefebvre, Pierre ; Centre Hospitalier Universitaire de Liège - CHU > Diabétologie,nutrition, maladies métaboliques

Scheen, André ; Université de Liège - ULiège > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques - Médecine interne générale

Language :

English

Title :

The use of acarbose in the prevention and treatment of hypoglycaemia.

Publication date :

1994

Journal title :

European Journal of Clinical Investigation

ISSN :

0014-2972

eISSN :

1365-2362

Publisher :

Blackwell Publishing, Oxford, United Kingdom

Volume :

24 Suppl 3

Pages :

40-4

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 05 June 2009

Statistics

Number of views

103 (0 by ULiège)

Number of downloads

0 (0 by ULiège)

More statistics

Scopus citations^®

Scopus citations^®
without self-citations

OpenCitations

OpenAlex citations

Bibliography

Hypoglycaemia , Andreani D., Marks V., Lefèbvre PJ,. New York:, Serono Symposia Publications from Raven Press; 1987, 38.
Sönksen P. Panel Discussion: Future aspects of α‐glucosidase inhibition , Creutzfeldt W., ed. Proceedings of the Second International Symposium on Acarbose. Berlin, November 1987., Springer‐Verlag, : Berlin; 1988, 185-193.
Gérard J., Luyckx AS, Lefèbvre PJ. (1984) Acarbose in reactive hypoglycaemia: a double‐blind study. Int J Clin Pharmacol 22:25-31.
Hanefeld M., Fischer S., Schulze J. (1991) Therapeutic potentials of acarbose as first‐line drug in NIDDM insufficiently treated with diet alone. Diabetes Care 14:732-737.
Willms B. (1992) Acarbose in non‐insulin‐dependent diabetes mellitus: combination with sulfonylureas and interaction with diet. New Aspects in Diabetes. Treatment Strategies with α‐glycosidase inhibitors , Lefèbvre PJ, Standl E.,. Berlin:, de Gruyter; 165-176.
Gérard J., Lefèbvre PJ, Luyckx AS. (1984) Glibenclamide pharmacokinetics in acarbose‐treated type 2 diabetics. European Journal of Clinical Pharmacology 27:233-236.
Raptis SA. (1992) European experience in the treatment of IDDM with acarbose in combination with insulin. New Aspects in Diabetes. Treatment Strategies with α‐glycosidase inhibitors , Lefèbvre PJ, Standl E.,. Berlin:, de Gruyter; 213-225.
Dimitriadis G., Karaiskos C., Raptis S. (1986) Effects of prolonged (6 months) α‐glucosidase inhibition on blood glucose control and insulin requirements in patients with insulin‐ dependent diabetes mellitus. Horm Metabol Res 18:253-255.
McCulloch DK, Kurtz AB, Tattersall RB. (1983) A new approach to the treatment of nocturnal hypoglycaemia using α‐glucosidase inhibition. Diabetes Care 6:483-487.
Gérard J., Jandrain B., Pirnay N. (1986) Utilization of oral sucrose load during exercise in humans. Effect of the α‐glucosidase inhibitor acarbose. Diabetes 35:1294-1301.
Marks V. (1987) Glycaemic stability in healthy subjects: fluctuations in blood glucose concentration during the day. Hypoglycaemia , Andreani D., Marks V., Lefèbvre PJ,. Serono Symposia Publications from Raven Press. New York:, Raven Press; 38:19-24.
Lefèbvre PJ. (1991) Hypoglycaemia or non‐hypoglycaemia. Diabetes 1991 , Rifkin H., Colwell JA, Taylor SI,. Proceedings of the 14th International Diabetes Federation Congress, Washington DC, 23–28 June 1991. Amsterdam:, Excerpta Medica; 757-761.
Mitrakou A., Ryan C., Veneman T. (1991) Hierarchy of glycemic thresholds for counterregulatory hormone secretion, symptoms, and cerebral dysfunction. Am J Physiol , (Endocrinol Metab 23);, E67, 74; 260.
Cox DJ, Gonder‐Frederick L., Clarke W. (1993) Driving decrements in Type I diabetes during moderate hypoglycaemia. Diabetes 42:239-243.
Lefèbvre PJ, Andreani D., Marks V., Creutzfeldt W. (1987) For the Participants to the Third International Symposium on Hypoglycaemia held in Rome, September 22–23, 1986. Statement on postprandial or reactive hypoglycaemia. Acta Diabetol Lat , Diabetologia 1988;31:68–69; Diab Med 1988;5:200; and Diabetes Care 1988;11:439; 24:353.
Palardy J., Havrankova J., Lepage R. (1989) Blood glucose measurements during symptomatic episodes in patients with suspected postprandial hypoglycaemia. New England Journal of Medicine 321:1421-1425.
Tamburrano G., Leonetti F., Sbraccia P., Giaccari A., Locuratolo N., Lala A. (1989) Increased insulin sensitivity in patients with idiopathic reactive hypoglycaemia. J Clin Endocrinol Metab 69:885-890.
Lefèbvre PJ. (1988) Hypoglycaemia: postprandial or reactive. Current Therapy in Endocrinology and Metabolism‐3 , Bardin CW,. Philadelphia:, B.C. Dekker Inc; 339-341.
Schrezenmeier J., Kasper H. (1982) Therapeutic effect of acarbose in reactive hypoglycaemia. Effects on Carbohydrate and Fat Metabolism , Creutzfeldt W., ed. Proceedings First International Symposium on Acarbose.,. International Congress Series 594. Amsterdam:, Excerpta Medica; 530.
Richard JL, Rodier M., Monnier L., Orsetti A., Mirouze J. (1988) Effect of acarbose on glucose and insulin response to sucrose load in reactive hypoglycaemia. Diab Metab (Paris) 14:114-118.
Hadji‐Georgopoulos A., Schmidt MI, Margolis S., Kowarski AA. (1980) Elevated hypoglycemic index and late hyperinsulinism in symptomatic postprandial hypoglycaemia. The Journal of Clinical Endocrinology & Metabolism 50:371-376.
Renard E., Parer‐Richard C., Richard JL (1990) Efficacité de l'administration aigüe d'un inhibiteur des α‐glucosidases intestinales (Miglitol) contre placebo chez des patients présentant une hypoglycémie réactionnelle. Diab Metab (Paris) 16:23.
Buchanan K.D, McLoughlin JC, Alam MJ. (1982) Acarbose in the dumping syndrome. Effects on Carbohydrate and Fat Metabolism , Creutzfeldt W., ed. Proceedings First International Symposium on Acarbose.,. International Congress Series 594. Amsterdam:, Excerpta Medica; 515.
Speth PAJ, Jansen JBMJ, Lamers CBHW. (1982) Acarbose and pectin in the dumping syndrome. Effects on Carbohydrate and Fat Metabolism , Creutzfeldt W., ed. Proceedings First International Symposium on Acarbose.,. International Congress Series 594. Amsterdam:, Excerpta Medica; 524.
Taylor RH, Jenkins DJA, Barker HM. (1982) Low‐dose acarbose and the dumping syndrome. Effects on Carbohydrate and Fat Metabolism , Creutzfeldt W., ed. Proceedings First International Symposium on Acarbose.,. International Congress Series 594. Amsterdam:, Excerpta Medica; 527.