The use of acarbose in the prevention and treatment of hypoglycaemia.

Lefebvre, Pierre; Scheen, André

doi:10.1111/j.1365-2362.1994.tb02255.x

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The use of acarbose in the prevention and treatment of hypoglycaemia.

Lefebvre, Pierre; Scheen, André

1994 • In European Journal of Clinical Investigation, 24 Suppl 3, p. 40-4

Peer Reviewed verified by ORBi

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https://hdl.handle.net/2268/14005

DOI
10.1111/j.1365-2362.1994.tb02255.x

PubMed
8001627

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Keywords :

Acarbose; Blood Glucose/metabolism; Diabetes Mellitus, Type 1/blood/drug therapy; Diabetes Mellitus, Type 2/blood/drug therapy; Eating; Humans; Hypoglycemia/drug therapy/prevention & control; Hypoglycemic Agents/therapeutic use; Sulfonylurea Compounds/therapeutic use; Trisaccharides/pharmacology/therapeutic use; alpha-Glucosidases/antagonists & inhibitors

Abstract :

[en] This paper reviews the use of acarbose in the prevention and treatment of hypoglycaemia. In diet- or sulfonylurea-treated patients, acarbose may reduce the incidence of late postprandial hypoglycaemia. In insulin-treated patients, acarbose treatment usually requires reduction of the insulin dose; one study has shown that 100 mg acarbose at night significantly reduces the incidence of mid-evening and nocturnal hypoglycaemia. Several studies have suggested acarbose to be a useful adjunct to the management of reactive hypoglycaemia in the non-diabetic patients. Long-term prospective studies are still needed to document this last indication of acarbose or other alpha-glycosidase inhibitors.

Disciplines :

Endocrinology, metabolism & nutrition

Author, co-author :

Lefebvre, Pierre ; Centre Hospitalier Universitaire de Liège - CHU > Diabétologie,nutrition, maladies métaboliques

Scheen, André ; Université de Liège - ULiège > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques - Médecine interne générale

Language :

English

Title :

The use of acarbose in the prevention and treatment of hypoglycaemia.

Publication date :

1994

Journal title :

European Journal of Clinical Investigation

ISSN :

0014-2972

eISSN :

1365-2362

Publisher :

Blackwell Publishing, Oxford, United Kingdom

Volume :

24 Suppl 3

Pages :

40-4

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 05 June 2009

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