Reference : Comment j'explore... une hypertriglyceridemie.
Scientific journals : Article
Human health sciences : Endocrinology, metabolism & nutrition
Comment j'explore... une hypertriglyceridemie.
[fr] How I study hypertriglyceridemia
Scheen, André mailto [Université de Liège - ULiège > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques - Médecine interne générale >]
Revue Médicale de Liège
CHU de Liège
Yes (verified by ORBi)
[en] Cholesterol, HDL/blood ; Decision Making ; Drug Therapy/adverse effects ; Eating ; Fasting ; Heart Diseases/etiology ; Humans ; Hypercholesterolemia/blood ; Hypertriglyceridemia/blood/diagnosis/etiology/genetics/metabolism/therapy ; Insulin Resistance ; Nutritional Physiological Phenomena ; Phenotype ; Risk Factors ; Syndrome ; Triglycerides/blood
[en] The strategy for the diagnosis of hypertriglyceridaemia comprises three successive steps. First, the physician should confirm the biological abnormality by at least one additional blood sample taken after an overnight fast; recent data, however, suggest that postprandial hypertriglyceridaemia may also represent a cardiovascular risk factor. Second, the phenotype of hypertriglyceridaemia should be considered as either isolated high triglyceride levels or hypertriglyceridaemia combined with hypercholesterolemia may be present; the combination of hypertriglyceridaemia with a low HDL cholesterol concentration or its association with the metabolic or insulin resistance syndrome should also be investigated. Third, all should be done in order to find the etiology of the hypertriglyceridaemia (by determining its genetic or nutritional origin, by excluding possible underlying pathologies, by looking for drugs able to increase serum triglyceride levels). These various steps should help the physician to take the final decision of treating one particular patient as well as to chose the most appropriate, nutritional or pharmacological, treatment.

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