Reference : Le cas clinique du mois. Une nephropathie galopante chez un patient diabetique de type 2.
Scientific journals : Article
Human health sciences : Urology & nephrology
Human health sciences : Endocrinology, metabolism & nutrition
http://hdl.handle.net/2268/12910
Le cas clinique du mois. Une nephropathie galopante chez un patient diabetique de type 2.
French
[en] Clinical case of the month. Galloping nephropathy in a patient with type 2 diabetes
Philips, Jean-Christophe mailto [Centre Hospitalier Universitaire de Liège - CHU > > Diabétologie,nutrition, maladies métaboliques >]
Scheen, André mailto [Université de Liège - ULiège > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques - Médecine interne générale >]
Firre, E. [> > > >]
Robin, M. [> > > >]
Cambier, P. [> > > >]
Lefebvre, Pierre [Centre Hospitalier Universitaire de Liège - CHU > > Diabétologie,nutrition, maladies métaboliques >]
1998
Revue Médicale de Liège
CHU de Liège
53
4
171-4
Yes (verified by ORBi)
National
0370-629X
Liège
Belgique
[en] Adult ; Antigen-Antibody Complex/analysis ; Antiviral Agents/therapeutic use ; Biopsy ; Diabetes Mellitus, Type 2/complications ; Diabetic Nephropathies/diagnosis ; Follow-Up Studies ; Glomerulonephritis/immunology/pathology/therapy/virology ; Hepacivirus/immunology ; Hepatitis C/diagnosis/immunology ; Humans ; Interferon-alpha/therapeutic use ; Male ; Renal Dialysis
[en] We report the case of a patient with insulin-requiring type 2 diabetes who exhibited a rapid deterioration of his renal function leading to haemodialysis in a few months. Various diagnosis were considered to explain this rapid deterioration, excluding diabetic nephropathy as major etiology. The exploration, especially renal biopsy, demonstrated the presence of a glomerulonephritis due to the deposition of immune complexes associated to active hepatitis C rather than diabetic glomerulosclerosis. A treatment with interferon-alpha allowed to partially restore renal function, this recovery permitting the interruption of hemodialysis, with a current follow-up of more than 6 months.
http://hdl.handle.net/2268/12910

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