No document available.
Abstract :
[en] Objectives: To evaluate quantitatively cytokeratin and vimentin staining in glandular and stromal cells of eutopic and ectopic endometrium.
DESIGN:
The investigation of cytokeratin and vimentin was carried out using the new computerized technology of image analysis.
SETTING:
University Hospital, Department of Gynecology.
PATIENTS:
Biopsies were taken from patients undergoing a laparoscopy for infertility (29 endometrial biopsies and 31 biopsies of peritoneal endometriosis). None of them were treated.
RESULTS:
Cyclic variations of cytokeratin and vimentin staining were noted in eutopic endometrium. The cytokeratin and vimentin staining pattern consistently was lower in ectopic endometrium than in eutopic endometrium.
CONCLUSIONS:
Endometriotic epithelial and stromal cells undergo a complex program of differentiation giving them histochemical characteristics similar to those observed in endometrium. Such a concomitant expression of antigenicity indicates their close relationship with their mesodermal müllerian origin.
Scopus citations®
without self-citations
27