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See detailLes ostraca IFAO OL 1850, 6126, 3498 et 3208. Quatre lettres relatives à des ṯȝy-ḫw
Sojic, Nathalie ULiege

in Cahiers de l'Académie hiératique (2018), 1

Edition de quatre ostraca portant des exercices épistolaires relatifs au porte-étendard à la droite du roi.

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See detailBioconcentration and half-life of quinalphos pesticide in rice-fish integration system in the Mekong Delta, Vietnam
Nguyen Quoc, Thinh; Tran Minh, Phu; Douny, Caroline ULiege et al

in Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, & Agricultural Wastes (2018), 53(35), 41

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See detailA component method for cold-formed steel beam-to-column bolted gusset plate joints
Bucmys, Zilvinas; Daniunas, Alfonsas; Jaspart, Jean-Pierre ULiege et al

in Thin-Walled Structures (2018), 123

Cold-formed steel elements are being used more frequently on construction sites because of the good strength-to-cost ratio. However, insufficient studies are published examining the properties of these ... [more ▼]

Cold-formed steel elements are being used more frequently on construction sites because of the good strength-to-cost ratio. However, insufficient studies are published examining the properties of these constructions. This paper presents a study of cold formed steel bolted gusset plate connections. A “three springs” mechanical model to calculate joint stiffness is presented. Then the results predicted through the proposed model are validated through comparisons to experimental and finite element results. [less ▲]

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See detailThe silicon isotopic composition of fine-grained river sediments and its relation to climate and lithology
Bayon, G.; Delvigne, C.; Ponzevera, E. et al

in Geochimica et Cosmochimica Acta (2018), 229

The δ30Si stable isotopic composition of silicon in soils and fine-grained sediments can provide insights into weathering processes on continents, with important implications on the Si budget of modern ... [more ▼]

The δ30Si stable isotopic composition of silicon in soils and fine-grained sediments can provide insights into weathering processes on continents, with important implications on the Si budget of modern and past oceans. To further constrain the factors controlling the distribution of Si isotopes in sediments, we have analysed a large number (n = 50) of separate size-fractions of sediments and suspended particulate materials collected near the mouth of rivers worldwide. This includes some of the world’s largest rivers (e.g. Amazon, Congo, Mackenzie, Mississippi, Murray-Darling, Nile, Yangtze) and rivers from the case study areas of the Congo River Basin and Northern Ireland. Silt-size fractions exhibit a mean Si isotopic composition (δ30Si = −0.21 ± 0.19‰; 2 s.d.) similar to that previously inferred for the upper continental crust. In contrast, clay-size fractions display a much larger range of δ30Si values from −0.11‰ to −2.16‰, which yield a global δ30Siclay of −0.57 ± 0.60‰ (2 s.d.) representative of the mean composition of the average weathered continental crust. Overall, these new data show that the Si isotopic signature transported by river clays is controlled by the degree of chemical weathering, as inferred from strong relationships with Al/Si ratios. At a global scale, the clay-bound Si isotopic composition of the world’s largest river systems demonstrates a link with climate, defining a general correlation with mean annual temperature (MAT) in corresponding drainage basins. While the distribution of Si isotopes in river sediments also appears to be influenced by the tectonic setting, lithological effects and sediment recycling from former sedimentary cycles, our results pave the way for their use as paleo-weathering and paleo-climate proxies in the sedimentary record. [less ▲]

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See detailTowards a global unified model of Europa's tenuous atmosphere
Plainaki, Christina G.; Cassidy, Timothy A.; Shematovich, Valery I. et al

in Space science reviews (2018)

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See detailMolecular characterization and gene silencing of Laccase 1 in the grain aphid, Sitobion avenae
Zhang, Yong ULiege; Fan, Jia; Francis, Frédéric ULiege et al

in Archives of Insect Biochemistry and Physiology (2018)

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See detailProtéger la protection sociale? Les droits fondamentaux peuvent-ils servir de bouclier pour les acquis sociaux?
Mormont, Hugo ULiege

in Revue de la Faculté de Droit de l'Université de Liège (2018), 1

La contribution examine comment certains droits fondamentaux pevent être mobilisés pour faire obstacle aux régressions sociales

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See detailKarst and Underground Landscapes in the Cretaceous Chalk and Calcarenite of the Belgian-Dutch Border—The Montagne Saint-Pierre
Willems, Luc ULiege; Rodet, Joël

in Landscapes and Landforms of Belgium and Luxembourg (2018)

The eastern part of the Hesbaye plateau, which extends into the Dutch Limburg, was excavated by many underground quarries that mainly exploited the Cretaceous chalk of the Maastrichtian. In this area, the ... [more ▼]

The eastern part of the Hesbaye plateau, which extends into the Dutch Limburg, was excavated by many underground quarries that mainly exploited the Cretaceous chalk of the Maastrichtian. In this area, the Meuse and its tributaries cut into the shallow dipping formations. Thus, entries of quarries usually are on hillsides. Most galleries sink horizontally along calcarenite layers, a coarse chalk also called «Tuffeau of Maastricht». The dimensions and extensions of these networks create real underground landscapes. These galleries intersect thousands of karst features and allow a privileged observation in three dimensions. These karst phenomena have dual characteristics: they mainly grow in a very porous lithology and outside fractures, so a context unfavourable to, a priori, a necessary concentrated weathering. Once dewatered, they cease to function, thus fossilizing a karst system in one of the rarely seen early genetic phases. [less ▲]

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See detailCapturing the multifaceted nature of energy poverty: Lessons from Belgium
Meyer, Sandrine; Holzemer, Laurence; Delbeke, Bart et al

in Energy Research & Social Science (2018), 40

Energy poverty is a major societal issue with both economic impacts and solidarity implications. Although its main drivers (e.g. insufficient income, bad quality housing, high energy prices) are widely ... [more ▼]

Energy poverty is a major societal issue with both economic impacts and solidarity implications. Although its main drivers (e.g. insufficient income, bad quality housing, high energy prices) are widely recognised, there is no common definition of energy poverty at the European level, let alone a common way of measuring the phenomenon. The energy poverty barometer for Belgium has been developed accordingly. It draws on a set of complementary indicators with the aim of grasping the multifaceted nature of energy poverty: excessive energy bills compared to available income (measured energy poverty), restriction in energy consumption below basic needs (hidden energy poverty) and self-reported difficulties to heat the housing correctly (perceived energy poverty). This paper presents and discusses the methodology followed to design this new tool in the Belgian context and its main findings. [less ▲]

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See detailEn quoi la «littératie» en santé intéresse-t-elle le clinicien de terrrrain? Un cadre stimulant pour réfléchir à l’efficacité pratique des soins
Henrard, Gilles ULiege; Vanmeerbeek, Marc ULiege; Belche, Jean Luc ULiege et al

in Revue Médicale de Liège (2018)

‘Health literacy’ refers to the ability to find, understand and use health information. It is a relatively new concept, which is becoming increasingly important but remains little known by clinicians ... [more ▼]

‘Health literacy’ refers to the ability to find, understand and use health information. It is a relatively new concept, which is becoming increasingly important but remains little known by clinicians. Still, insufficient levels of health literacy in our patients are common, underestimated and negatively associated with numerous health indicators. A set of practical tools are already available to the clinician. The aim of this article is to present the concept to clinicians and emphasize how it could revitalize reflection on the effectiveness of our interventions in the field. Physicians could take a leadership role in putting the concept of health literacy on the agenda for health care quality improvement. [less ▲]

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See detailUnravelling the ‘ingredients’ of energy consumption: Exploring home-related practices in Belgium
Maréchal, Kevin ULiege; Holzemer, Laurence

in Energy Research & Social Science (2018), 39(May 2018), 19-28

To look at energy consumption through a different lens, we have developed the conceptual framework of habitual practices. The objective of the present paper is to propose an empirical application of this ... [more ▼]

To look at energy consumption through a different lens, we have developed the conceptual framework of habitual practices. The objective of the present paper is to propose an empirical application of this framework, with the aim of unravelling the constitutive ‘ingredients’ of energy-consuming practices. Therefore, we investigate whether discussing the relationship of people with their homes could help circumventing the methodological difficulties that inevitably arise when trying to approach less tangible (albeit crucial) elements such as norms and attached meanings. The empirical material comes from group conversations where participants discussed the extent to which a home has to be practical, comfortable and convivial in connection with a series of elements. The results confirm that this methodological setting generated useful insights for a finer understanding of energy-consuming practices and their underlying drivers. A related crucial finding is the role of key appliances – those with more contrasted use and attached meanings – which appear to mediate the interplay between comfort, conviviality, and practicality. A promising avenue for future research would thus be to further investigate the role of those key appliances as potential markers of wider tendencies in energy consumption and useful for designing segmentation strategies. [less ▲]

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See detailDispersal capacity of Haematopota spp. and Stomoxys calcitrans using a mark–release–recapture approach in Belgium
Lempereur, Laetitia ULiege; Sohier, Charlotte; Smeets, François et al

in Medical and Veterinary Entomology (2018)

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See detailScience-fiction et jeu vidéo
Delbouille, Julie ULiege; Dozo, Björn-Olav ULiege; Jousten, Lison ULiege

in ReS Futurae : Revue d'Etudes sur la Science-Fiction (2018), 12

Lorsque Spacewar!, considéré comme un des premiers jeux vidéo, voit le jour en 1962 dans les salles du Massachussets Institute of Technology, il marque le début d’une longue relation entre ce médium et la ... [more ▼]

Lorsque Spacewar!, considéré comme un des premiers jeux vidéo, voit le jour en 1962 dans les salles du Massachussets Institute of Technology, il marque le début d’une longue relation entre ce médium et la science-fiction. À l’heure où l’informatique est encore fort peu micro, la thématique spatiale que ce précurseur exploite présente en effet un avantage certain : celui de déployer à l’écran un « espace dont la principale caractéristique est le vide [...] un lieu qui exige moins de puissance de calcul » (Triclot, 2011). De l’émergence de cette culture hacker dans les années 1960 à la production actuelle, le jeu vidéo a constamment puisé dans les ressorts propres à la science-fiction – que ce soit les accents cyberpunk d’un Deus Ex : Human Revolution (Square Enix, 2011), l’uchronie d’un Wolfenstein : The New Order (Bethesda Softworks, 2014) ou encore la dystopie constitutive d’un Bioshock (2K Games, 2007). Cette richesse spécifique a pourtant été peu interrogée. [less ▲]

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See detailBeat-by-Beat Estimation of the Left Ventricular Pressure–Volume Loop Under Clinical Conditions
Davidson, S.; Pretty, C.; Kamoi, S. et al

in Annals of Biomedical Engineering (2018), 46(1), 171-185

This paper develops a method for the minimally invasive, beat-by-beat estimation of the left ventricular pressure–volume loop. This method estimates the left ventricular pressure and volume waveforms that ... [more ▼]

This paper develops a method for the minimally invasive, beat-by-beat estimation of the left ventricular pressure–volume loop. This method estimates the left ventricular pressure and volume waveforms that make up the pressure–volume loop using clinically available inputs supported by a short, baseline echocardiography reading. Validation was performed across 142,169 heartbeats of data from 11 Piétrain pigs subject to two distinct protocols encompassing sepsis, dobutamine administration and clinical interventions. The method effectively located pressure–volume loops, with low overall median errors in end-diastolic volume of 8.6%, end-systolic volume of 17.3%, systolic pressure of 19.4% and diastolic pressure of 6.5%. The method further demonstrated a low overall mean error of 23.2% predicting resulting stroke work, and high correlation coefficients along with a high percentage of trend compass ‘in band’ performance tracking changes in stroke work as patient condition varied. This set of results forms a body of evidence for the potential clinical utility of the method. While further validation in humans is required, the method has the potential to aid in clinical decision making across a range of clinical interventions and disease state disturbances by providing real-time, beat-to-beat, patient specific information at the intensive care unit bedside without requiring additional invasive instrumentation. © 2017, Biomedical Engineering Society. [less ▲]

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See detailAbnormally adherent and invasive placenta: a spectrum disorder in need of a name
Collins, Sally; CHANTRAINE, Frédéric ULiege; Morgan, Terry et al

in Ultrasound in Obstetrics & Gynecology (2018)

There is little doubt that the worldwide Cesarean delivery epidemic has led to an increased incidence of abnormally adherent and invasive placentation. The significant impact that this disorder has on ... [more ▼]

There is little doubt that the worldwide Cesarean delivery epidemic has led to an increased incidence of abnormally adherent and invasive placentation. The significant impact that this disorder has on maternal morbidity and mortality has led to a flurry of publications in the literature concerning all aspects of the condition. These papers have arisen from many sources, notably pathologists, epidemiologists, obstetricians and radiologists. [less ▲]

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See detailReview of: F. Brentano & G.T. Fechner, Briefwechsel über Psychophysik 1874-1878 (M. Antonelli, Ed.)
Seron, Denis ULiege

in Grazer Philosophische Studien (2018), 95(1), 153-157

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See detailMelanoma antigen-D2 controls cell cycle progression and modulates the DNA damage response.
Trussart, Charlotte ULiege; Pirlot, Céline; Di Valentin, Emmanuel ULiege et al

in Biochemical Pharmacology (2018)

Overexpression of the ubiquitous type II melanoma antigen-D2 (MAGED2) in numerous types of cancer suggests that this protein contributes to carcinogenesis, a well-documented characteristic of other MAGE ... [more ▼]

Overexpression of the ubiquitous type II melanoma antigen-D2 (MAGED2) in numerous types of cancer suggests that this protein contributes to carcinogenesis, a well-documented characteristic of other MAGE proteins. Modification of MAGED2 intracellular localization during cell cycle phases and following treatment with camptothecin (CPT) and phosphorylation by ATM/ATR following ionizing irradiation led us to investigate the molecular functions of MAGED2 in the cellular response to DNA damage. Cell cycle regulators, cell cycle progression, and bromodeoxyuridine (BrdU) incorporation were compared between MAGED2-sufficient and -depleted U2OS cells following exposure to CPT. At 24 h post-CPT removal, MAGED2-depleted cells had lower levels of p21 and p27, and there was an increase in S phase BrdU-positive cells with a concurrent decrease in cells in G2. These cell cycle modifications were p21-independent, but ATR-, SKP2-, and CDC20-dependent. Importantly, while MAGED2 depletion reduced CHK2 phosphorylation after 8 h of CPT treatment, it enhanced and prolonged CHK1 phosphorylation after a 24 h recovery period, indicating sustained ATR activation. MAGED2 depletion had no impact on cell survival under our experimental conditions. In summary, our data indicate that MAGED2 reduced CPT-related replicative stress, suggesting a role for this protein in genomic stability. [less ▲]

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See detailFlorescu: A Memorandum of Understanding Finally before the Court
Rocca, Marco ULiege

in International Labor Rights Case Law (2018), 1

The claimants oppose a reform of the Romanian state pension that, under certain conditions, prohibits civil servants from receiving income from both a pension and work. The provision was adopted to ... [more ▼]

The claimants oppose a reform of the Romanian state pension that, under certain conditions, prohibits civil servants from receiving income from both a pension and work. The provision was adopted to implement the Memorandum of Understanding of 2009 between Romania and the EU, and is criticized on the basis of the right to property and of nondiscrimination law. The Court concludes that, though it has standing to scrutinize the Memorandum, because implementation falls under the scope of the EU Charter of Fundamental Rights, the restriction to the right to property was justified and proportionate in light of the objective of rationalize public spending. In turn, the difference of treatment the claimants invoked does not fall under discrimination legislation. [less ▲]

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See detailAssessment of tomato (Solanum lycopersicum L.) producers'exposure level to pesticides, in Kouka and Toussiana (Burkina Faso)
Son, Diakalia ULiege; Zerbo, Fabrice K. B.; Bonzi, Schémaeza et al

in International Journal of Environmental Research and Public Health (2018), 15(2), 17

To assess producers’ exposure level to pesticides in vegetable production in Burkina Faso, a study was carried out in 2016 and 2017 among 30 tomato producers in the municipalities of Kouka and Toussiana ... [more ▼]

To assess producers’ exposure level to pesticides in vegetable production in Burkina Faso, a study was carried out in 2016 and 2017 among 30 tomato producers in the municipalities of Kouka and Toussiana. Eighteen (18) commercial formulations were identified, with more than 50% of pesticides destined for cotton production. Eleven active substances have been identified and the most frequently used are -cyhalothrin (35%), acetamiprid (22%) and profenofos (13%). The most commonly used chemical families are pyrethroids (28%) and organophosphates (18%). The study revealed a low level of training for producers, a high use of pesticides according to the Frequency Treatment Indicator, and a very low level of protection used by producers. The Health Risk Index shows that active substances such as methomyl, -cyhalothrin and profenofos present very high risk to operators’ health. Based on the UK-POEM model, the predictive exposure levels obtained varied from 0.0105 mg/kg body weight/day to 1.7855 mg/kg body weight/day, which is several times higher than the Acceptable Operator Exposure Level. However, the study also shows that exposure can be greatly reduced if the required Personal Protective Equipment is worn. Producers’ awareness and training on integrated pest management are necessary to reduce the risks linked to the pesticides use in Burkina Faso. [less ▲]

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See detailLa charte de Venise en France : acteurs, réception, interprétations 1957-1976
Houbart, Claudine ULiege

in Apuntes - Journal of Cultural Heritage Studies (2018), (30),

Il y a deux ans, à l’occasion du cinquantenaire de la Charte de Venise, colloques et publications ont proclamé, à travers le monde, l’importance historique de ce « monument de la doctrine » et parfois ... [more ▼]

Il y a deux ans, à l’occasion du cinquantenaire de la Charte de Venise, colloques et publications ont proclamé, à travers le monde, l’importance historique de ce « monument de la doctrine » et parfois même, réaffirmé l’actualité de ses principes. Les recherches que j’ai consacrées à Raymond M. Lemaire (1921-1997), dans le cadre de ma thèse de doctorat, m’ont donné l’occasion, à travers l’examen des archives très complètes du conservateur belge, d’éclairer la « fabrique » de la charte. Signée par 23 experts présents au congrès, la première version de celle-ci se révèle avoir été, en réalité, rédigée par un groupe de cinq personnes, parmi lesquels Piero Gazzola et Roberto Pane, membres du comité d’organisation du congrès – et auxquels la paternité de la charte est souvent attribuée sur base d’un document préparatoire rédigé à quatre mains –, les belges Raymond M. Lemaire et Paul Philippot, mais aussi un français, Jean Sonnier, vice-président, 7 ans plus tôt, du comité organisateur du Congrès international des architectes et techniciens des monuments historiques à Paris et ACMH. Par ailleurs, mes recherches ont mis en lumière le fait que tout en faisant, aujourd’hui encore, figure de monument intangible ou même, de « constitution de l’ICOMOS » à l’échelle internationale, la charte a pourtant fait l’objet, six ans à peine après son adoption, de projets de révision : deux de ses auteurs, P. Gazzola et R. Lemaire, devenus respectivement Président et Secrétaire général de l’ICOMOS, considéraient en effet le document inefficace face aux enjeux montants de la « réanimation » des ensembles urbains. Bien que tous les comités nationaux de l’ICOMOS aient été associés à ces réflexions, qui allaient se poursuivre, sans aboutir, jusque 1990, le rôle de deux français mérite à nouveau d’être souligné: Jean Sonnier, pour sa collaboration avec R. Lemaire à une version révisée de la charte en 1978, et François Sorlin, administrateur civil chargé des sites, en oeuvrant avec Lemaire et Gazzola, pour le Comité des monuments et des sites du Conseil de l’Europe, à l’élaboration des principes qui deviendraient ceux de la conservation intégrée en 1975. Cette étroite implication de deux personnalités françaises lors de la rédaction et de la révision de la charte m’a convaincue de la nécessité d’explorer plus avant le contexte français, là où ma thèse s’était cantonnée aux contextes belge et italien et ceci d’autant plus que la France me paraissait, sur base d’une connaissance superficielle, avoir été moins réceptive – en dehors de personnalités isolées telles qu’Yves-Marie Froidevaux, Bernard Vitry ou Pierre Prunet – aux aspects de la charte les plus proches des principes de la restauration critique. Dans son ouvrage de 2003, X. Laurent révèle que Bertrand Monnet pensait être l’un des seuls ACMH à connaitre le document, et souligne qu’il « est hasardeux de parler d’influence de la charte de Venise avant le milieu des années 1970 » et que « le dépouillement des archives révèle qu’il [lui] a fallu plus de dix ans (…) pour devenir une référence en France », ceci même si Françoise Bercé considère quant à elle la charte comme un événement majeur des années 1960. Cette question n’a, à mon sens, pas suffisamment retenu l’attention des historiens de l’architecture français. C’est pourquoi, ayant eu la chance de bénéficier du statut de chercheur invité à l’INHA en avril et mai dernier, je me suis employée à clarifier les contributions françaises à la charte, sa réception en France et les possibles particularités de ses interprétations par les ACMH en prenant pour point de départ un dépouillement systématique de la revue Monuments historiques afin d’identifier l’apparition des références explicites (ou même implicites) aux principes de la charte ainsi qu’un corpus de projets représentatifs. Alors que j’avais programmé un dépouillement de 1957 à 1976 (du Congrès de Paris au colloque Les restaurations françaises et la Charte de Venise), il s’est avéré nécessaire de poursuivre les investigations jusqu’en 1990, date de la 9e assemblée générale de l’ICOMOS à Lausanne, lors de laquelle les contributions majeures de comité français ont consisté à faire le point sur l’application de la charte de France durant les 20 dernières années. J’ai pu constater que si jusqu’au colloque de 1976, les références à la charte sont essentiellement implicites, dans les années qui suivent, les réflexions se succèdent rapidement, le plus souvent à l’initiative du comité français de l’ICOMOS, dont le premier président avait été Jean Sonnier. Ce sont les résultats de cette recherche que je me propose de présenter dans un article pour la revue Apuntes, autour des quatre balises chronologiques que sont 1957, 1964, 1976 et 1990, en illustrant mon propos par des projets et manifestations (colloques, expositions) représentatifs à propos desquels j’ai approfondi la recherche aux archives de la Médiathèque de l’architecture et du patrimoine. [less ▲]

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See detailDenitrification, anaerobic ammonium oxidation, and dissimilatory nitrate reduction to ammonium in an East African Great Lake (Lake Kivu)
Roland, Fleur ULiege; Darchambeau, François; Borges, Alberto ULiege et al

in Limnology and Oceanography (2018)

We investigated anaerobic nitrogen (N) cycling in the water column of Lake Kivu, a deep meromictic tropical lake in East Africa. Data were collected at one station in the Northern Basin and one in the ... [more ▼]

We investigated anaerobic nitrogen (N) cycling in the water column of Lake Kivu, a deep meromictic tropical lake in East Africa. Data were collected at one station in the Northern Basin and one in the Southern Basin, during two sampling campaigns (June 2011—dry season, and February 2012—rainy season). Short-term incubations of sulfide-free water with 15N-labeled substrates revealed high potential denitrification and dissimilatory nitrate reduction to ammonium (DNRA) rates (up to 350 and 36 nmol N produced L−1 h−1, respectively), while anaerobic ammonium oxidation (anammox) was lower (up to 3.3 nmol N produced L−1 h−1). However, anammox rates were 15 nmol N produced L−1 h−1 when 15 NH4+ was added at depths where NH4+ concentrations were very low (< 1 μmol L−1). With the addition of 5 μmol L−1 of 15 NO3− and 10 μmol L−1 of H2S, denitrification and anammox were stimulated in the Northern Basin, while the increase of DNRA rates was less notable. In the Southern Basin, the addition of H2S decreased denitrification rates, probably because of competition with DNRA, which increased, while no effect was observed on anammox. This study puts into evidence the co-occurrence of denitrification, anammox and DNRA, for the first time in a great tropical lake, and underlines the spatial heterogeneity of these processes. Contrary to numerous reports in literature, we show that anammox can significantly occur in presence of H2S, suggesting that the contribution of anammox in the N cycle may be underestimated. [less ▲]

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See detailHow can integrated valuation of ecosystem services help understanding and steering agroecological transitions?
Dendoncker, Nicolas; Boeraeve, Fanny ULiege; Crouzat, Emilie et al

in Ecology and Society (2018), 23(1), 12

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See detailChanging your political mind: The impact of a metaphor on citizens’ representations and preferences for federalism
Reuchamps, Min; Dodeigne, Jérémy; Perrez, Julien ULiege

in Regional & Federal Studies (2018)

Federalism is often presented through metaphors, but little is known about the impact of such metaphors. Two experiments were conducted in Belgium presenting federalism as Tetris – with control and ... [more ▼]

Federalism is often presented through metaphors, but little is known about the impact of such metaphors. Two experiments were conducted in Belgium presenting federalism as Tetris – with control and treatment groups – in order to grasp the influence of this metaphor. The first experiment reveals that being exposed to text with the Tetris metaphor influences respondents’ representations of federalism towards a more institutional representation and towards more regional autonomy. The second experiment confirms the importance of the text, and more specifically of the metaphor, if political knowledge is taken into account. Respondents with a lower level of political knowledge are those who are influenced by the metaphor, whereas respondents with a higher level are not. Therefore, framing the future of Belgian federalism using the metaphor of Tetris does matter: it affects both individuals’ representations of the federalization process and, consequently, their preferences vis-à-vis the institutional future of the country. [less ▲]

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See detailBref commentaire de l’arrêté royal du 18 juin 2017 relatif à la passation des marchés publics dans les secteurs spéciaux
Cariat, Nicolas; Vrancken, Martin ULiege

in Revue du droit des industries de réseau (2018)

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See detailTonian (Neoproterozoic) eukaryotic and prokaryotic organic-walled microfossils from the upper Visingsö Group, Sweden
Loron, Corentin ULiege; Moczydłowska, Małgorzata

in Palynology (2018), 42(2), 220-254

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See detailNatural Antisense Transcripts: Molecular Mechanisms and Implications in Breast Cancers.
Latge, Guillaume ULiege; Poulet, Christophe ULiege; Bours, Vincent ULiege et al

in International Journal of Molecular Sciences (2018), 19(1),

Natural antisense transcripts are RNA sequences that can be transcribed from both DNA strands at the same locus but in the opposite direction from the gene transcript. Because strand-specific high ... [more ▼]

Natural antisense transcripts are RNA sequences that can be transcribed from both DNA strands at the same locus but in the opposite direction from the gene transcript. Because strand-specific high-throughput sequencing of the antisense transcriptome has only been available for less than a decade, many natural antisense transcripts were first described as long non-coding RNAs. Although the precise biological roles of natural antisense transcripts are not known yet, an increasing number of studies report their implication in gene expression regulation. Their expression levels are altered in many physiological and pathological conditions, including breast cancers. Among the potential clinical utilities of the natural antisense transcripts, the non-coding|coding transcript pairs are of high interest for treatment. Indeed, these pairs can be targeted by antisense oligonucleotides to specifically tune the expression of the coding-gene. Here, we describe the current knowledge about natural antisense transcripts, their varying molecular mechanisms as gene expression regulators, and their potential as prognostic or predictive biomarkers in breast cancers. [less ▲]

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See detailCompte rendu de Éléonore Reverzy, “Portrait de l’artiste en fille de joie. La littérature publique”
Stienon, Valérie ULiege

in Francofonia (2018), 74

De Fleur de Marie à la fille Élisa et à Boule de Suif, nombreuses sont les incarnations de la prostituée dans la littérature du XIXe siècle, où s’observe d’ailleurs un sous-genre du roman de la ... [more ▼]

De Fleur de Marie à la fille Élisa et à Boule de Suif, nombreuses sont les incarnations de la prostituée dans la littérature du XIXe siècle, où s’observe d’ailleurs un sous-genre du roman de la prostitution en vogue à partir des années 1870. Ces représentations ne sont pourtant qu’une infime partie de la problématique brillamment étudiée par Éléonore Reverzy: plus qu’un personnage ou un motif, la fille de joie est une métaphore qui signifie à d’autres niveaux que la seule dimension référentielle. Dès lors, «la déplier dans le discours critique perme[t] d’en saisir les points d’appui dans les champs moral, politique, esthétique, et d’en comprendre les actualisations fictionnelles» (p.54). Au croisement de ces différents champs se situent les discours dénonçant ou valorisant les positions des écrivains dans le système des lettres, car la figure de la prostituée permet d’exprimer les tensions entre la dimension immatérielle de la littérature et la nécessaire implication de l’argent dans son élaboration, en un siècle où la publicité, avec son puff, ses séductions et son racolage, devient un passage obligé. [less ▲]

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See detailULg Spectra: An Interactive Software Tool To Improve Undergraduate Students’ Structural Analysis Skills
Agnello, Armélinda ULiege; Carré, Cyril ULiege; Billen, Roland ULiege et al

in Journal of Chemical Education (2018), 95

The analysis of spectroscopic data to solve chemical structures requires practical skills and drills. In this context, we have developed ULg Spectra, a computer-based tool designed to improve the ability ... [more ▼]

The analysis of spectroscopic data to solve chemical structures requires practical skills and drills. In this context, we have developed ULg Spectra, a computer-based tool designed to improve the ability of learners to perform complex reasoning. The identification of organic chemical compounds involves gathering and interpreting complementary information from mass, infrared, Raman, and nuclear magnetic resonance spectra. Here, special attention is paid to one-dimensional 1H and 13C NMR spectra and to two-dimensional NMR spectra because these techniques particularly require extensive interactive data manipulation. ULg Spectra offers tutorial-drill materials, including spectra that are “authentic” in the sense that they contain solvent and impurity traces rather than being “idealized” spectra often found in textbook examples. A public version is accessible online free of charge. The exam results for two groups of students, one having used ULg Spectra for extra home-based training and the other not, were compared. Statistical data demonstrated higher performance for the “trained” students compared with the control group. [less ▲]

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See detailLandmark detection in 2D bioimages for geometric morphometrics: a multi-resolution tree-based approach.
Vandaele, Rémy ULiege; Aceto, Jessica; Muller, Marc ULiege et al

in Scientific Reports (2018), 8(1), 538

The detection of anatomical landmarks in bioimages is a necessary but tedious step for geometric morphometrics studies in many research domains. We propose variants of a multi-resolution tree-based ... [more ▼]

The detection of anatomical landmarks in bioimages is a necessary but tedious step for geometric morphometrics studies in many research domains. We propose variants of a multi-resolution tree-based approach to speed-up the detection of landmarks in bioimages. We extensively evaluate our method variants on three different datasets (cephalometric, zebrafish, and drosophila images). We identify the key method parameters (notably the multi-resolution) and report results with respect to human ground truths and existing methods. Our method achieves recognition performances competitive with current existing approaches while being generic and fast. The algorithms are integrated in the open-source Cytomine software and we provide parameter configuration guidelines so that they can be easily exploited by end-users. Finally, datasets are readily available through a Cytomine server to foster future research. [less ▲]

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See detailcompte rendu de : Maria Nowak Wills in the Roman Empire: A Documentary Approach Warsaw, JJP, 2015
Rochette, Bruno ULiege

in Latomus (2018), 77(1), 281-284

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See detailHigh diversity, high insular endemism and recent origin in the lichen genus Sticta (lichenized Ascomycota, Peltigerales) in Madagascar and the Mascarenes
Simon, Antoine ULiege; Goffinet, Bernard; Magain, Nicolas et al

in Molecular Phylogenetics & Evolution (2018), 22

Lichen biodiversity and its generative evolutionary processes are practically unknown in the MIOI (Madagascar and Indian Ocean Islands) biodiversity hotspot. We sought to test the hypothesis that ... [more ▼]

Lichen biodiversity and its generative evolutionary processes are practically unknown in the MIOI (Madagascar and Indian Ocean Islands) biodiversity hotspot. We sought to test the hypothesis that lichenized fungi in this region have undergone a rapid radiation, following a single colonization event, giving rise to narrow endemics, as is characteristic of other lineages of plants. We extensively sampled specimens of the lichen genus Sticta in the Mascarene archipelago (mainly Réunion) and in Madagascar, mainly in the northern range (Amber Mt and Marojejy Mt) and produced the fungal ITS barcode sequence for 148 thalli. We further produced a four-loci data matrix for 68 of them, representing the diversity and geographical distribution of ITS haplotypes. We reconstructed the phylogenetic relationships within this group, established species boundaries with morphological context, and estimated the date of the most recent common ancestor. Our inferences resolve a robust clade comprising 31 endemic species of Sticta that arose from the diversification following a single recent (c. 11 Mya) colonization event. All but three species have a very restricted range, endemic to either the Mascarene archipelago or a single massif in Madagascar. The first genus of lichens to be studied with molecular data in this region underwent a recent radiation, exhibits micro-endemism, and thus exemplifies the biodiversity characteristics found in other taxa in Madagascar and the Mascarenes. [less ▲]

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See detailAssociations of lifetime traumatic experience with dysfunctional eating patterns and post-surgery weight-loss in adults with obesity: a retrospective study
Ruffault, Alexis ULiege; Vaugeois, Fanny; Barsamian, Charles et al

in Stress and Health (2018)

This study aimed to examine the associations of lifetime traumatic experience with pre- and post-surgery eating pathology and postoperative weight-loss in a sample of bariatric surgery patients using ... [more ▼]

This study aimed to examine the associations of lifetime traumatic experience with pre- and post-surgery eating pathology and postoperative weight-loss in a sample of bariatric surgery patients using electronic medical record (EMR) data. Pre-surgery lifetime exposure to traumatic event, pre- and post-surgery dysfunctional eating patterns, and post-operative total and excess weight losses were extracted from EMR of 200 bariatric surgery patients in 2013 and 2014. Logistic regression analyses were conducted. 60.5% of the patients (81.5% women; age=44.4±11.5 years; BMIpre=44.9±5.5 kg/m2) reported that they were exposed to a traumatic event during their lifetime. Before surgery, trauma exposure was associated with impulsive, compulsive or restrictive eating patterns (OR=2.40), overeating or disturbed eating (OR=1.55), and grazing or night eating behaviors (OR=1.72). After surgery, trauma exposure was associated with lower total weight loss at 6 months (OR=2.06) and 24 months (OR=2.06), and to overeating or disturbed eating (OR=1.53) 12 months after surgery. Bariatric surgery candidates with a history of trauma exposure could benefit from closer medical, dietetic, and/or psychological follow-up care to avoid insufficient postoperative weight loss as well as reappearance of dysfunctional eating patterns after surgery. [less ▲]

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See detailL'administation fiscale peut-elle réclamer un impôt lié à une transaction pénale homologuée par le tribunal?
Herve, Luc ULiege

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2018), 2018/11

L'administration fiscale, "victime privilégiée", est-elle autorisée à réclamer un impôt lié à des faits qui ont fait l'objet d'une transaction pénale homologuée par une décision coulée en force de chose ... [more ▼]

L'administration fiscale, "victime privilégiée", est-elle autorisée à réclamer un impôt lié à des faits qui ont fait l'objet d'une transaction pénale homologuée par une décision coulée en force de chose jugée ? Après une description des faits et de l'arrêt de la Cour d'appel de Mons du 11 octobre 2016, l'institution de la transaction pénale est examinée au regard de l'administration fiscale, la portée de l'arrêt et ses conséquences sont analysées et la modification législative dont la transaction pénale devrait faire l'objet est évoquée. [less ▲]

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See detailAddressing the determinants of built-up expansion and densification processes at the regional scale
Mustafa, Ahmed Mohamed El Saeid ULiege; Van Rompaey, Anton; Cools, Mario ULiege et al

in Urban Studies (2018)

An in-depth understanding of the main factors behind built-up development is a key prerequisite for designing policies dedicated to a more efficient land use. Infill development policies are essential to ... [more ▼]

An in-depth understanding of the main factors behind built-up development is a key prerequisite for designing policies dedicated to a more efficient land use. Infill development policies are essential to curb sprawl and allow a progressive recycling of low-density areas inherited from the past. This paper examines the controlling factors of built-up expansion and densification processes in Wallonia (Belgium). Unlike the usual urban/built-up expansion studies, our approach considers various levels of built-up densities to distinguish between different types of developments, ranging from low-density extensions (or sprawl) to high-density infill development. Belgian cadastral data for 1990, 2000, and 2010 were used to generate four classes of built-up areas, namely, non-, low-, medium- and high-density areas. A number of socioeconomic, geographic, and political factors related to built-up development were operationalized following the literature. We then used a multinomial logistic regression model to analyze the effects of these factors on the transitions between different densities in the two decades between 1990 and 2010. The findings indicate that all the controlling factors show distinctive variations based on density. More specifically, the centrality of zoning policies in explaining expansion processes is highlighted. This is especially the case for high-density expansions. In contrast, physical and neighborhood factors play a larger role in infill development, especially for dense infill development. [less ▲]

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See detailOptimal enforcement of competition policy: the commitments procedure under uncertainty
Gautier, Axel ULiege; Petit, Nicolas ULiege

in European Journal of Law and Economics (2018), 45(2), 195-224

The introduction of a commitments procedure in EU antitrust policy (Article 9 of Council Regulation 1/2003) has entitled the the European Commission to extensively settle cases of alleged anticompetitive ... [more ▼]

The introduction of a commitments procedure in EU antitrust policy (Article 9 of Council Regulation 1/2003) has entitled the the European Commission to extensively settle cases of alleged anticompetitive conduct. In this paper, we use a formal model of law enforcement to identify the optimal procedure to remedy cases in a context of partial legal uncertainty (Katsoulacos and Ulph in Eur J Law Econ 41(2):255–282, 2016). We discuss in particular the merits of a policy of selective commitments where firms either take strong commitments or are investigated under the standard infringement procedure. [less ▲]

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See detailReview on the effects of potential prebiotics on controlling intestinal enteropathogens Salmonella and Escherichia coli in pig production
Tran, Thi Hanh Tham ULiege; Everaert, Nadia ULiege; Bindelle, Jérôme ULiege

in Journal of Animal Physiology and Animal Nutrition (2018), 102

Salmonella enterica serotypes (Salmonella sp.) are the second cause of bacterial foodborne zoonoses in humans after campylobacteriosis. Pork is the third most important cause for outbreak-associated ... [more ▼]

Salmonella enterica serotypes (Salmonella sp.) are the second cause of bacterial foodborne zoonoses in humans after campylobacteriosis. Pork is the third most important cause for outbreak-associated salmonellosis, and colibacillosis is the most important disease in piglets and swine. Attachment to host cells, translocation of effector proteins into host cells, invasion and replication in tissues are the vital virulence steps of these pathogens that help them to thrive in the intestinal environment and invade tissues. Feed contamination is an important source for Salmonella infection in pig production. Many on-farm feeding strategies intervene to avoid the introduction of pathogens onto the farm by contaminated feeds or to reduce infection pressure when pathogens are present. Among the latter, prebiotics could be effective at protecting against these enteric bacterial pathogens. Nowadays, a wide range of molecules can potentially serve as prebiotics. Here, we summarize the prevalence of Salmonella sp. and Escherichia coli in pigs, understanding of the mechanisms by which pathogens can cause disease, the feed related to pathogen contamination in pigs and detail the mechanisms on which prebiotics are likely to act in order to fulfil their protective action against these pathogens in pig production. Many different mechanisms involve the inhibition of Salmonella and E. coli by prebiotics such as coating the host surface, modulation of intestinal ecology, downregulating the expression of adhesin factors or virulence genes, reinforcing the host immune system. [less ▲]

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See detailCross-talk between primary osteocytes and bone marrow macrophages for osteoclastogenesis upon collagen treatment
Elango, Jeevithan; Sanchez, Christelle ULiege; de Val, José Eduardo Maté Sánchez et al

in Scientific Reports (2018), 8(1), 5318

Homeostasis of osteoclast formation from bone marrow macrophages (BMM) is regulated by paracrine signals of the neighbourhood bone cells particularly mesenchymal stem cells (MSC), osteoblasts and ... [more ▼]

Homeostasis of osteoclast formation from bone marrow macrophages (BMM) is regulated by paracrine signals of the neighbourhood bone cells particularly mesenchymal stem cells (MSC), osteoblasts and osteocytes (OC). Besides paracrine cues, collagen and glycosaminoglycan are involved in controlling bone homeostasis. Towards this approach, different molecular weight collagens were reacted with MSC, OC and BMM to understand the bone homeostasis activity of collagen. The up-regulating effect of collagens on osteogenic cell growth was confirmed by the presence of mineralized nodules in the osteoblastogenic lineage cells and increased osteogenic stimulatory gene expression. The decreased BMM-derived TRAP+ osteoclasts number and osteoclastogenic regulatory gene expression of OC could demonstrate the exploitive osteoclastogenic activity of collagens. Osteoclastogenesis from BMM was triggered by paracrine cues of OC in some extend, but it was down-regulated by collagen. Overall, the effect of collagen on osteoclastogenesis and osteoblastogenesis may depend on the molecular weight of collagens, and collagen suppresses osteoclastogenesis, at least in part by downregulating the secretion of cytokines in OC. [less ▲]

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See detailCompte rendu du livre de Kevin V. Mulcahy « Public Culture, Cultural Identity, Cultural Policy. Comparative Perspectives »
Lowies, Jean-Gilles ULiege

in Revue Française de Science Politique (2018), 68(4),

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See detailBook Review of B. Mabille: Rencontres. Hegel à l'épreuve du dialogue philosophique
Lejeune, Guillaume ULiege

in Bulletin of the Hegel Society of Great Britain [=Hegel Bulletin] (2018)

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See detailChemical Constituents of the Leaves of Caloncoba welwitschii Gilg.
Douanla, Pascal D.; Tchuendem, Marguerite Hortence K.; Tchinda, Alembert T. et al

in Phytochemistry Letters (2018), 23(October 2017), 5--8

Two new compounds namely acetylcaloncobaside (1) and friedocaloncobic acid (2) were isolated from the leaves of Caloncoba welwitschii together with six known compounds. Their structures were determined by ... [more ▼]

Two new compounds namely acetylcaloncobaside (1) and friedocaloncobic acid (2) were isolated from the leaves of Caloncoba welwitschii together with six known compounds. Their structures were determined by standard spectroscopic methods including one- and two-dimensional NMR, EI-MS, and HRESIMS. The new compounds were established as kaempferol 4′,7-dimethoxy-3-O-(3″,4″,6″-O-triacetyl)-β-null-glucopyranoside (1) and 15β-hydroxy-3-oxo-28-friedelanoic acid (2). The isolated compounds were evaluated for their ability to inhibit the 3D7 strain of Plasmodium falciparum, using the semi-automated in vitro model with parasite lactate dehydrogenase assay. [less ▲]

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See detailMinor Genres and Marginal Realities: Kei Miller's Blog Posts and Facebook Notes
Romdhani, Rebecca ULiege

in Journal of Postcolonial Writing (2018), 54(1), 95-107

In his blog posts and Facebook notes, Jamaican author Kei Miller writes about his experiences in Glasgow and the US, emphasizing the different "realities" and notions of "reality" coexisting in these ... [more ▼]

In his blog posts and Facebook notes, Jamaican author Kei Miller writes about his experiences in Glasgow and the US, emphasizing the different "realities" and notions of "reality" coexisting in these places. More specifically, Miller's writings call attention to the hierarchies operating to elevate some "realities" and silence others. This article argues that Miller's pieces can be regarded as a hybrid of two minor genres, the blog and the essay, as well as of the subgenre of creative non-fiction. This hybridity mirrors and illuminates some of the themes explored in the writings, such as authenticity, authority, subjectivity and voice. When Miller's online posts are read alongside his essays – and precisely because they are in a virtual space that allows for contributions from his readers in the comment section – they help to expose the hierarchies that he writes about, and demonstrate the urgency of giving voice to marginalized realities. [less ▲]

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See detailNext-generation, personalised, model-based critical care medicine: A state-of-the art review of in silico virtual patient models, methods, and cohorts, and how to validation them
Chase, J. G.; Preiser, J.-C.; Dickson, J. L. et al

in BioMedical Engineering OnLine (2018), 17(1),

Critical care, like many healthcare areas, is under a dual assault from significantly increasing demographic and economic pressures. Intensive care unit (ICU) patients are highly variable in response to ... [more ▼]

Critical care, like many healthcare areas, is under a dual assault from significantly increasing demographic and economic pressures. Intensive care unit (ICU) patients are highly variable in response to treatment, and increasingly aging populations mean ICUs are under increasing demand and their cohorts are increasingly ill. Equally, patient expectations are growing, while the economic ability to deliver care to all is declining. Better, more productive care is thus the big challenge. One means to that end is personalised care designed to manage the significant inter- and intra-patient variability that makes the ICU patient difficult. Thus, moving from current "one size fits all" protocolised care to adaptive, model-based "one method fits all" personalised care could deliver the required step change in the quality, and simultaneously the productivity and cost, of care. Computer models of human physiology are a unique tool to personalise care, as they can couple clinical data with mathematical methods to create subject-specific models and virtual patients to design new, personalised and more optimal protocols, as well as to guide care in real-time. They rely on identifying time varying patient-specific parameters in the model that capture inter- and intra-patient variability, the difference between patients and the evolution of patient condition. Properly validated, virtual patients represent the real patients, and can be used in silico to test different protocols or interventions, or in real-time to guide care. Hence, the underlying models and methods create the foundation for next generation care, as well as a tool for safely and rapidly developing personalised treatment protocols over large virtual cohorts using virtual trials. This review examines the models and methods used to create virtual patients. Specifically, it presents the models types and structures used and the data required. It then covers how to validate the resulting virtual patients and trials, and how these virtual trials can help design and optimise clinical trial. Links between these models and higher order, more complex physiome models are also discussed. In each section, it explores the progress reported up to date, especially on core ICU therapies in glycemic, circulatory and mechanical ventilation management, where high cost and frequency of occurrence provide a significant opportunity for model-based methods to have measurable clinical and economic impact. The outcomes are readily generalised to other areas of medical care. © 2018 The Author(s). [less ▲]

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See detailPitfalls in the measurement of muscle mass; a need for a reference standard.
Buckinx, Fanny ULiege; Landi, Francesco; Cesari, francesco et al

in Journal of Cachexia, Sarcopenia and Muscle (2018)

Background: All proposed definitions of sarcopenia include the measurement of muscle mass, but the techniques and threshold values used vary. Indeed, the literature does not establish consensus on the ... [more ▼]

Background: All proposed definitions of sarcopenia include the measurement of muscle mass, but the techniques and threshold values used vary. Indeed, the literature does not establish consensus on the best technique for measuring lean body mass. Thus, the objective measurement of sarcopenia is hampered by limitations intrinsic to assessment tools. The aim of this study was to review the methods to assess muscle mass and to reach consensus on the development of a reference standard. Methods: Literature reviews were performed by members of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis working group on frailty and sarcopenia. Face-to-face meetings were organized for the whole group to make amendments and discuss further recommendations. Results: A wide range of techniques can be used to assess muscle mass. Cost, availability, and ease of use can determine whether the techniques are better suited to clinical practice or are more useful for research. No one technique subserves all requirements but dual energy X-ray absorptiometry could be considered as a reference standard (but not a gold standard) for measuring muscle lean body mass. Conclusions: Based on the feasibility, accuracy, safety, and low cost, dual energy X-ray absorptiometry can be considered as the reference standard for measuring muscle mass. [less ▲]

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See detailA frame-semantic approach to the Source-Goal asymmetry: Synchronic and diachronic evidence from Ancient Greek
Georgakopoulos, Athanasios ULiege

in Constructions and Frames (2018)

Situated within the frame semantics paradigm, this paper investigates the asymmetrical behavior of Sources and Goals of motion in Homeric and Classical Greek. In particular, based on a corpus of 26 works ... [more ▼]

Situated within the frame semantics paradigm, this paper investigates the asymmetrical behavior of Sources and Goals of motion in Homeric and Classical Greek. In particular, based on a corpus of 26 works covering four text types, it is shown that (a) motion verbs display, regardless of their semantic class, preference for Goal PATHS compared to Source ones; (b) the frame that a verb belongs to affects the type of PATH chosen only to a certain degree and, in particular, to a degree that does not change the Source-Goal imbalance; (c) semantically incongruent motion verb-PATH combinations are naturally less frequent than congruent combinations, but within the category of incongruent combinations the tokens are distributed in a way that reflects the prevalence of Goals; (d) the number of markers for the encoding of Goal is higher than that of Source; and (e) Source and Goal markers interact with Place ones in an asymmetrical way: Goal markers come to encode Place and, similarly, Place markers come to express Goal. Conversely, the interaction of markers exhibiting Source–Place polysemy is unidirectional, in the sense that none of these markers was originally used to encode Place alone. Theoretical implications of the study are discussed and directions for future investigations are suggested. [less ▲]

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See detailLLAMA: nuclear stellar properties of Swift-BAT AGN and matched inactive galaxies
Lin, M.-Y.; Davies, R. I.; Hicks, E. K. S. et al

in Monthly Notices of the Royal Astronomical Society (2018), 473

In a complete sample of local 14–195 keV selected active galactic nuclei (AGNs) and inactive galaxies, matched by their host galaxy properties, we study the spatially resolved stellar kinematics and ... [more ▼]

In a complete sample of local 14–195 keV selected active galactic nuclei (AGNs) and inactive galaxies, matched by their host galaxy properties, we study the spatially resolved stellar kinematics and luminosity distributions at near-infrared wavelengths on scales of 10–150 pc, using SINFONI on the VLT. In this paper, we present the first half of the sample, which comprises 13 galaxies, eight AGNs and five inactive galaxies. The stellar velocity fields show a disc-like rotating pattern, for which the kinematic position angle is in agreement with the photometric position angle obtained from large scale images. For this set of galaxies, the stellar surface brightness of the inactive galaxy sample is generally comparable to the matched sample of AGN, but extends to lower surface brightness. After removal of the bulge contribution, we find a nuclear stellar light excess with an extended nuclear disc structure, which exhibits a size-luminosity relation. While we expect the excess luminosity to be associated with a dynamically cooler young stellar population, we do not typically see a matching drop in dispersion. This may be because these galaxies have pseudo-bulges in which the intrinsic dispersion increases towards the centre. And although the young stars may have an impact in the observed kinematics, their fraction is too small to dominate over the bulge and compensate the increase in dispersion at small radii, so no dispersion drop is seen. Finally, we find no evidence for a difference in the stellar kinematics and nuclear stellar luminosity excess between these active and inactive galaxies. [less ▲]

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See detailDispersal and alternative breeding site fidelity strategies in an amphibian
Denoël, Mathieu ULiege; Dalleur, séverine; Langrand, Estelle et al

in Ecography (2018)

Dispersal (i.e., movement from a natal or breeding site to another breeding site) is a central process in ecology and evolution as it affects the eco-evolutionary dynamics of spatially structured ... [more ▼]

Dispersal (i.e., movement from a natal or breeding site to another breeding site) is a central process in ecology and evolution as it affects the eco-evolutionary dynamics of spatially structured populations. Dispersal evolution is regulated by the balance between costs and benefits, which is influenced by the individual phenotype (i.e., phenotype-dependent dispersal) and environmental factors (i.e., condition-dependent dispersal). Even though these processes have been extensively studied in species with simple life cycles, our knowledge about these mechanisms in organisms displaying complex life cycles remains fragmentary. In fact, little is specifically known about how the interplay between individual and environmental factors may lead to alternative dispersal strategies that, in turn, lead to the coexistence of contrasted site fidelity phenotypes. In this paper, we examined breeding dispersal in a pond-breeding amphibian, the great crested newt (Triturus cristatus), within usual walking distances for a newt. We took advantage of recent developments in multi-event capture-recapture models and used capture-recapture data (946 newts marked) collected in a spatially structured population occupying a large pond network (73 ponds). We showed a high rate of breeding site infidelity (i.e., pond use) and the coexistence of two dispersal phenotypes, namely, a highly pond faithful phenotype and a dispersing phenotype. Individuals that were site faithful at time t-1 were therefore more likely to remain site faithful at time t. Our results also demonstrated that the probability that individuals belong to one or the other dispersal phenotypes depended on environmental and individual factors. In particular, we highlighted the existence of a dispersal syndrome implying a covariation pattern among dispersal behavior, body size, and survival. Our work opens new research prospects in the evolution of dispersal in organisms displaying complex life cycles and raises interesting questions about the evolutionary pathways that contribute to the diversification of movement strategies in the wild. [less ▲]

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See detailVerbal short-term memory shows a specific association with receptive but not productive vocabulary measures in Down syndrome
Majerus, Steve ULiege; Barisnikov, Koviljka

in Journal of Intellectual Disability Research [=JIDR] (2018), 62

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See detailSurfactin protects wheat against Zymoseptoria tritici and activates both salicylic acid- and jasmonic acid-dependent defense responses
Le Mire, Géraldine ULiege; Siah, Ali; Brisset, Marie-Noëlle et al

in Agriculture (2018), 8

Natural elicitors induce plant resistance against a broad spectrum of diseases, and are currently among the most promising biocontrol tools. The present study focuses on the elicitor properties of the ... [more ▼]

Natural elicitors induce plant resistance against a broad spectrum of diseases, and are currently among the most promising biocontrol tools. The present study focuses on the elicitor properties of the cyclic lipopeptide surfactin on wheat, in order to stimulate the defenses of this major crop against the challenging fungal pathogen Zymoseptoria tritici. The protection efficacy of surfactin extracted from the strain Bacillus amyloliquefaciens S499 was investigated through greenhouse trials. Surfactin protected wheat by 70% against Z. tritici, similarly to the chemical reference elicitor Bion®50WG. In vitro biocidal assays revealed no antifungal activities of surfactin towards the pathogen. A biomolecular RT-qPCR based low-density microarray tool was used to study the relative expression of 23 wheat defense genes. Surfactin significantly induced wheat natural defenses by stimulating both salicylic acid- and jasmonic acid-dependent signaling pathways. Surfactin was successfully tested as an elicitor on the pathosystem wheat–Z. tritici. These results promote further sustainable agricultural practices and the reduction of chemical inputs. [less ▲]

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See detailMultidimensional Quantum Mechanical Modeling of Electron Transfer and Electronic Coherence in Plant Cryptochromes: The Role of Initial Bath Conditions
Mendive-Tapia, David; Mangaud, Etienne; Firmino, Thiago et al

in Journal of Physical Chemistry B (2018), 122

A multidimensional quantum mechanical protocol is used to describe the photoinduced electron transfer and electronic coherence in plant cryptochromes without any semiempirical, e.g., experimentally ... [more ▼]

A multidimensional quantum mechanical protocol is used to describe the photoinduced electron transfer and electronic coherence in plant cryptochromes without any semiempirical, e.g., experimentally obtained, parameters. Starting from a two-level spin-boson Hamiltonian we look at the effect that the initial photoinduced nuclear bath distribution has on an intermediate step of this biological electron transfer cascade for two idealized cases. The first assumes a slow equilibration of the nuclear bath with respect to the previous electron transfer step that leads to an ultrafast decay with little temperature dependence; while the second assumes a prior fast bath equilibration on the donor potential energy surface leading to a much slower decay, which contrarily displays a high temperature dependence and a better agreement with previous theoretical and experimental results. Beyond Marcus and semiclassical pictures these results unravel the strong impact that the presence or not of equilibrium initial conditions has on the electronic population and coherence dynamics at the quantum dynamics level in this and conceivably in other biological electron transfer cascades. [less ▲]

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See detailExtended adjuvant intermittent letrozole versus continuous letrozole in postmenopausal women with breast cancer (SOLE): a multicentre, open-label, randomised, phase 3 trial.
Colleoni, Marco; Luo, Weixiu; Karlsson, Per et al

in Lancet Oncology (2018), 19(1), 127-138

BACKGROUND: In animal models of breast cancer, resistance to continuous use of letrozole can be reversed by withdrawal and reintroduction of letrozole. We therefore hypothesised that extended intermittent ... [more ▼]

BACKGROUND: In animal models of breast cancer, resistance to continuous use of letrozole can be reversed by withdrawal and reintroduction of letrozole. We therefore hypothesised that extended intermittent use of adjuvant letrozole would improve breast cancer outcome compared with continuous use of letrozole in postmenopausal women. METHODS: We did the multicentre, open-label, randomised, parallel, phase 3 SOLE trial in 240 centres (academic, primary, secondary, and tertiary care centres) in 22 countries. We enrolled postmenopausal women of any age with hormone receptor-positive, lymph node-positive, and operable breast cancer for which they had undergone local treatment (surgery with or without radiotherapy) and had completed 4-6 years of adjuvant endocrine therapy. They had to be clinically free of breast cancer at enrolment and without evidence of recurrent disease at any time before randomisation. We randomly assigned women (1:1) to treatment groups of either continuous use of letrozole (2.5 mg/day orally for 5 years) or intermittent use of letrozole (2.5 mg/day orally for 9 months followed by a 3-month break in years 1-4 and then 2.5 mg/day during all 12 months of year 5). Randomisation was done by principal investigators or designee at respective centres through the internet-based system of the International Breast Cancer Study Group, was stratified by type of previous endocrine therapy (aromatase inhibitors only vs selective oestrogen receptor modulators only vs both therapies), and used permuted block sizes of four and institutional balancing. No one was masked to treatment assignment. The primary endpoint was disease-free survival, analysed by the intention-to-treat principle using a stratified log-rank test. All patients in the intention-to-treat population who initiated protocol treatment during their period of trial participation were included in the safety analyses. This study is registered with ClinicalTrials.gov, number NCT00553410, and EudraCT, number 2007-001370-88; and long-term follow-up of patients is ongoing. FINDINGS: Between Dec 5, 2007, and Oct 8, 2012, 4884 women were enrolled and randomised after exclusion of patients at a non-adherent centre, found to have inadequate documentation of informed consent, immediately withdrew consent, or randomly assigned to intervention groups in error. 4851 women comprised the intention-to-treat population that compared extended intermittent letrozole use (n=2425) with continuous letrozole use (n=2426). After a median follow-up of 60 months (IQR 53-72), disease-free survival was 85.8% (95% CI 84.2-87.2) in the intermittent letrozole group compared with 87.5% (86.0-88.8) in the continuous letrozole group (hazard ratio 1.08, 95% CI 0.93-1.26; p=0.31). Adverse events were reported as expected and were similar between the two groups. The most common grade 3-5 adverse events were hypertension (584 [24%] of 2417 in the intermittent letrozole group vs 517 [21%] of 2411 in the continuous letrozole group) and arthralgia (136 [6%] vs 151 [6%]). 54 patients (24 [1%] in the intermittent letrozole group and 30 [1%] in the continuous letrozole group) had grade 3-5 CNS cerebrovascular ischaemia, 16 (nine [<1%] vs seven [<1%]) had grade 3-5 CNS haemorrhage, and 40 (19 [1%] vs 21 [1%]) had grade 3-5 cardiac ischaemia. In total, 23 (<1%) of 4851 patients died while on trial treatment (13 [<1%] of 2417 patients in the intermittent letrozole group vs ten [<1%] of 2411 in the continuous letrozole group). INTERPRETATION: In postmenopausal women with hormone receptor-positive breast cancer, extended use of intermittent letrozole did not improve disease-free survival compared with continuous use of letrozole. An alternative schedule of extended adjuvant endocrine therapy with letrozole, including intermittent administration, might be feasible and the results of the SOLE trial support the safety of temporary treatment breaks in selected patients who might require them. FUNDING: Novartis and the International Breast Cancer Study Group. [less ▲]

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See detailIdentification and characterization of EYD1, encoding an erythritol dehydrogenase in Yarrowia lipolytica and its application to bioconvert erythritol into erythrulose
Carly, F.; Steels, Sébastien ULiege; Telek, Samuel ULiege et al

in Bioresource Technology (2018), 247

In this study, gene YALI0F01650g has been isolated and characterized. Several experimental evidences suggest that the identified gene, renamed EYD1, encodes an erythritol dehydrogenase. An efficient ... [more ▼]

In this study, gene YALI0F01650g has been isolated and characterized. Several experimental evidences suggest that the identified gene, renamed EYD1, encodes an erythritol dehydrogenase. An efficient bioreactor process for the bioconversion of erythritol into erythrulose was also developed. Using constitutive expression of EYD1 in a Y. lipolytica mutant containing a disrupted EYK1 gene, which encodes erythrulose kinase, erythrulose could be synthesized from erythritol at a rate of 0.116 g/gDCW.h and with a bioconversion yield of 0.64 g/g. © 2017 Elsevier Ltd [less ▲]

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See detailRegards en coin et mains tendues. Notes sur les collaborations (rêvées, effectives, avortées) de Rimbaud
Saint-Amand, Denis ULiege

in Parade Sauvage (2018), 28

On peut observer, au fil de la trajectoire littéraire d’Arthur Rimbaud, différents moments où la tentation de la collaboration se manifeste sous des formes variées : c’est tantôt une demande explicite de ... [more ▼]

On peut observer, au fil de la trajectoire littéraire d’Arthur Rimbaud, différents moments où la tentation de la collaboration se manifeste sous des formes variées : c’est tantôt une demande explicite de cooptation au consensus parnassien formulée à un aîné mieux doté en capital symbolique, tantôt la participation effective à un projet collectif ; ce sont à d’autres moments des échanges plus ou moins directs, sur le mode complice de la critique amicale, de l’influence, voire de l’innutrition ou sur celui, plus distant et moins bienveillant, de la parodie railleuse et de la caricature. Mais ces saillies collaboratives font long feu : d’une part, Rimbaud se révèle rapidement déçu par l’échange entre pairs ; d’autre part, il ne respecte pas toujours les codes et les attentes des sociabilités littéraires de son temps. [less ▲]

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See detailThe PseudoDojo: Training and grading a 85 element optimized norm-conserving pseudopotential table
Setten, M. J. Van; Giantomassi, M.; Bousquet, Eric ULiege et al

in Computer Physics Communications (2018)

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See detailLong-term care social insurance: How to avoid big losses?
Klimaviciute, Justina ULiege; Pestieau, Pierre ULiege

in International Tax and Public Finance (2018), 25(1), 99-139

Long-term care (LTC) needs are expected to rapidly increase in the next decades, and at the same time, the main provider of LTC, namely the family, is stalling. This calls for more involvement of the ... [more ▼]

Long-term care (LTC) needs are expected to rapidly increase in the next decades, and at the same time, the main provider of LTC, namely the family, is stalling. This calls for more involvement of the state that today covers <20% of these needs and most often in an inconsistent way. Besides the need to help the dependent poor, there is a mounting concern in the middle class that a number of dependent people are incurring costs that could force them to sell all their assets. In this paper, we study the design of a social insurance program that meets this concern. Following Arrow (Am Econ Rev 53:941–973, 1963), we suggest a policy that is characterized by complete insurance above a deductible amount. [less ▲]

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See detailModalité et Sémantique. A propos de la réception de Hegel par William James
Lejeune, Guillaume ULiege

in Hegel-Studien (2018), 51

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See detailEliciting cultural heritage values: landscape preferences versus representative images of the city
Ginzarly, Manal ULiege; Teller, Jacques ULiege

in Journal of Cultural Heritage Management and Sustainable Development (2018)

Purpose–In 2011, UNESCO recommended the application of a value-based landscape approach to cultural heritage conservation. In this framework, culture in its manifold expressions is considered as an ... [more ▼]

Purpose–In 2011, UNESCO recommended the application of a value-based landscape approach to cultural heritage conservation. In this framework, culture in its manifold expressions is considered as an embrace for the social, economic, and environmental pillars of sustainable development. There is a need to unveil the different cultural values generated from the interaction between people and their environment since these values will help cities maintain their unique identity and integrity. Accordingly, the purpose of this paper is to present the results of a survey method intended to assess the range of cultural values attributed by people to the historic urban landscape. Design/methodology/approach–This paper is an experimental inquiry that combines a qualitative and a quantitative approach. It is designed to distinguish the different interpretations and outlooks of people to the historic urban landscape. It integrates landscape preference studies with investigation on representative images of the city and assesses these in relation to activities, feelings, and valued aspects of landscapes. Findings–The main finding is that the most preferred scenes of the city are not the ones that represent best the city. Results exposed two sides of the historic urban landscape and related heritage values. The first is associated with the scenic beauty of the landscape and its aesthetic values, while the second is reflected in ordinary landscapes and everyday practices. Originality/value– This paper provides an insight on the different interpretations and meanings of the historic urban landscape throughout the city. It provides an empirical evidence that ordinary landscapes are of great heritage value as they surpass all aspects of human environmental interaction to contribute to the image that societies make of themselves. [less ▲]

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See detailSingle- versus multiple-sample method to measure glomerular filtration rate.
DELANAYE, Pierre ULiege; Flamant, Martin; Dubourg, Laurence et al

in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2018)

Background: There are many different ways to measure glomerular filtration rate (GFR) using various exogenous filtration markers, each having their own strengths and limitations. However, not only the ... [more ▼]

Background: There are many different ways to measure glomerular filtration rate (GFR) using various exogenous filtration markers, each having their own strengths and limitations. However, not only the marker, but also the methodology may vary in many ways, including the use of urinary or plasma clearance, and, in the case of plasma clearance, the number of time points used to calculate the area under the concentration-time curve, ranging from only one (Jacobsson method) to eight (or more) blood samples. Methods: We collected the results obtained from 5106 plasma clearances (iohexol or 51Cr-ethylenediaminetetraacetic acid (EDTA)) using three to four time points, allowing GFR calculation using the slope-intercept method and the Brochner-Mortensen correction. For each time point, the Jacobsson formula was applied to obtain the single-sample GFR. We used Bland-Altman plots to determine the accuracy of the Jacobsson method at each time point. Results: The single-sample method showed within 10% concordances with the multiple-sample method of 66.4%, 83.6%, 91.4% and 96.0% at the time points 120, 180, 240 and >/=300 min, respectively. Concordance was poorer at lower GFR levels, and this trend is in parallel with increasing age. Results were similar in males and females. Some discordance was found in the obese subjects. Conclusion: Single-sample GFR is highly concordant with a multiple-sample strategy, except in the low GFR range (<30 mL/min). [less ▲]

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See detailRasa3 controls turnover of endothelial cell adhesion and vascular lumen integrity by a Rap1-dependent mechanism
Molina Ortiz, Patricia ULiege; Orban, Tanguy ULiege; Martin, Maud et al

in PLOS Genetics (2018)

Rasa3 is a GTPase activating protein of the GAP1 family which targets R-Ras and Rap1. Although catalytic inactivation or deletion of Rasa3 in mice leads to severe hemorrhages and embryonic lethality, the ... [more ▼]

Rasa3 is a GTPase activating protein of the GAP1 family which targets R-Ras and Rap1. Although catalytic inactivation or deletion of Rasa3 in mice leads to severe hemorrhages and embryonic lethality, the biological function and cellular location of Rasa3 underlying these defects remains unknown. Here, using a combination of loss of function studies in mouse and zebrafish as well as in vitro cell biology approaches, we identify a key role for Rasa3 in endothelial cells and vascular lumen integrity. Specific ablation of Rasa3 in the mouse endothelium, but not in megakaryocytes and platelets, lead to embryonic bleeding and death at mid-gestation, recapitulating the phenotype observed in full Rasa3 knock-out mice. Reduced plexus/sprouts formation and vascular lumenization defects were observed when Rasa3 was specifically inactivated in mouse endothelial cells at the postnatal or adult stages. Similar results were obtained in zebrafish after decreasing Rasa3 expression. In vitro, depletion of Rasa3 in cultured endothelial cells increased β1 integrin activation and cell adhesion to extracellular matrix components, decreased cell migration and blocked tubulogenesis. During migration, these Rasa3-depleted cells exhibited larger and more mature adhesions resulting from a perturbed dynamics of adhesion assembly and disassembly which significantly increased their life time. These defects were due to a hyperactivation of the Rap1 GTPase and blockade of FAK/Src signaling. Finally, Rasa3-depleted cells showed reduced turnover of VE-cadherin-based adhesions resulting in more stable endothelial cell-cell adhesion and decreased endothelial permeability. Altogether, our results indicate that Rasa3 is a critical regulator of Rap1 in endothelial cells which controls adhesions properties and vascular lumen integrity; its specific endothelial cell inactivation results in occluded blood vessels, hemorrhages and early embryonic death in mouse, mimicking thus the Rasa3-/- mouse phenotype. [less ▲]

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See detailRussia and its shared neighbourhoods: a comparative analysis of Russia-EU and Russia-China relations in the EU's Eastern neighbourhood and Central Asia
Samokhvalov, Vsevolod ULiege

in Contemporary Politics (2018), 24(1), 30-45

This article examines the conditions under which great powers succeed or fail to shape a cooperative security agenda in their shared neighbourhoods. It compares Russia's interactions with the EU and with ... [more ▼]

This article examines the conditions under which great powers succeed or fail to shape a cooperative security agenda in their shared neighbourhoods. It compares Russia's interactions with the EU and with China in their respective shared neighbourhoods: the EU's Eastern Neighbourhood region and Central Asia. The article applies a synthetic framework. It analyses how the interplay between three factors–ideas, capabilities and circumstantial factors such, as the personalities of leading politicians,–shape the process of interaction between great powers. It starts from a comparison of the images of the two regions in Russia's mind-set because such images provide cognitive lenses through which powers make sense of political developments in shared neighbourhoods. The article then moves to show how change in the balance of power (soft and hard) created enabling conditions for competition/collaboration. Finally, the article shows how specific circumstantial factors led to or shaped the Russian-European conflict. At the same time, similar factors prevented Russian-Chinese conflict in Central Asia. © 2017 Informa UK Limited, trading as Taylor & Francis Group. [less ▲]

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See detailPerformances of local poultry breed fed black soldier fly larvae reared on horse manure
Moula, Nassim ULiege; Scippo, Marie-Louise ULiege; Douny, Caroline ULiege et al

in Animal Nutrition (2018)

In poultry, feed based on maggots, like larvae of Black Soldier fly (Hermetia illucens) is an attractive option to substitute current ingredients which are expensive and often in direct or indirect ... [more ▼]

In poultry, feed based on maggots, like larvae of Black Soldier fly (Hermetia illucens) is an attractive option to substitute current ingredients which are expensive and often in direct or indirect competition with human food. Little information is currently available on the utility of these larvae in poultry feed, so goals of this study were to determine whether larvae could be reared on horse manure under traditional farming conditions and to evaluate the growth performances of a local poultry fed these larvae and the fatty acids profiles of their meat. After freezing and thawing, larvae were introduced in the feed of Ardennaise chickens between 30 and 80 days of age. Birds in the control group received a commercial standard feed while those in the treatment group received the same commercial feed in which 8% was substituted with whole fresh larvae corresponding to 2% on a dry matter basis. Mean ± standard errors of larval length and weight were 20.67 ± 2.21 mm and 0.14 ± 0.02 g, respectively. Mean larval percentages of dry matter and of substances extractable in diethyl ether were 24.6% and 23.1%, respectively. Larval fatty acids profiles were predominantly composed of lauric (28.1%) and palmitic (22.0%) acids. Least squares means of weekly weights of chicken, adjusted for the effects of sex, replication and initial weights, were significantly higher (P < 0.05) by 77.03 ± 53.37 g in larvae-fed than in control chickens. All the other measurements were not statistically different between larvae-fed and control chicken, including fatty acid profiles, protein content and ω6/ω3 ratio. In conclusion, the use of black soldier fly larvae in the diet of local chicken breed may be an alternative to the use of soy. [less ▲]

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See detailVolcanic influence of Mt. Fuji on the watershed of Lake Motosu and its impact on the lacustrine sedimentary record
Lamair, Laura ULiege; Hubert, Aurelia ULiege; Yamamoto, Shinya et al

in Sedimentary Geology (2018)

Lacustrine sediments are particularly sensitive to modifications within the lake catchment. In a volcanic area, sedimentation rates are directly affected by the history of the volcano and its eruptions ... [more ▼]

Lacustrine sediments are particularly sensitive to modifications within the lake catchment. In a volcanic area, sedimentation rates are directly affected by the history of the volcano and its eruptions. Here, we investigate the impact of Mt. Fuji Volcano (Japan) on Lake Motosu and its watershed. The lacustrine infill is studied by combining seismic reflection profiles and sediment cores. We show evidence of changes in sedimentation patterns during the depositional history of Lake Motosu. The frequency of large mass-transport deposits recorded within the lake decreases over the Holocene. Before ~8000 cal yr BP, large sublacustrine landslides and turbidites were filling the lacustrine depression. After 8000 cal yr BP, only one large sublacustrine landslide was recorded. The change in sedimentation pattern coincides with a change in sediment accumulation rate. Over the last 8000 cal yr BP, the sediment accumulation rate was not sufficient enough to produce large sublacustrine slope failures. Consequently, the frequency of large masstransport deposits decreased and only turbidites resulting from surficial slope reworking occurred. These constitute the main sedimentary infill of the deep basin. We link the change in sediment accumulation rate with (i) climate and vegetation changes; and (ii) theMt. Fuji eruptions which affected the LakeMotosu watershed by reducing its size and strongly modified its topography. Moreover, this study highlights that the deposition of turbidites in the deep basin of Lake Motosu is mainly controlled by the paleobathymetry of the lakefloor. Two large mass-transport deposits, occurring around ~8000 cal yr BP and ~2000 cal yr BP respectively, modified the paleobathymetry of the lakefloor and therefore changed the turbidite depositional pattern of Lake Motosu. [less ▲]

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See detailPrediction of the Incidence of Falls and Deaths Among Elderly Nursing Home Residents: The SENIOR Study.
Buckinx, Fanny ULiege; Croisier, Jean-Louis ULiege; Reginster, Jean-Yves ULiege et al

in Journal of the American Medical Directors Association (2018), 19(1), 18-24

OBJECTIVE: The objective of this study was to evaluate, among nursing home residents, the extent to which the various operational definitions of frailty predict mortality and falls at 1 year. METHODS: We ... [more ▼]

OBJECTIVE: The objective of this study was to evaluate, among nursing home residents, the extent to which the various operational definitions of frailty predict mortality and falls at 1 year. METHODS: We studied 662 participants from the Sample of Elderly Nursing home Individuals: An Observational Research (SENIOR) cohort aged 83.2 ± 8.99 years, including 484 (72.5%) women and living in nursing homes. Among this cohort, 584 and 565 participants, respectively, were monitored over 12 months for mortality assessment and for occurrence of falls (ie, by mean of their medical records). Each patient was subjected to a clinical examination at baseline, during which many original clinical characteristics were collected. Stepwise regression analyses were carried out to predict mortality and falls. RESULTS: Among the participants included in the study, 93 (15.9%) died and 211 (37.3%) experienced a fall during the 1-year of follow-up. After adjustment, none of the definitions of frailty assessed predicted the 1-year occurrence of negative health outcomes. When comparing the clinical characteristics of deceased participants and those still alive, being a man (OR = 1.89; 95% CI: 1.19-3.01; P = .002) and being diagnosed with sarcopenia (OR = 1.7; 95% CI: 1.1-2.92; P = .03) were independent factors associated with 1-year mortality. Other independent factors that were significantly associated with the 1-year occurrence of falls were the results obtained with the Tinetti test (OR = 0.93; 95% CI: 0.87-0.98; P = .04), with the grip strength test (OR = 0.95; 95% CI: 0.90-0.98, P = .03), and with the isometric strength test of elbow extensors (OR = 0.93; 95%CI: 0.87-0.97; P = .04). CONCLUSIONS: Within the operational definitions of frailty assessed, none is sufficiently sensitive to predict the occurrence of falls and deaths at 1 year among nursing home residents. Globally, the frequency of undesirable health outcomes seems to be higher among participants with lower muscle strength and mobility. Medical strategy or adapted physical activity, with the aim of improving specific isometric muscle strength and mobility could potentially, but significantly, reduce the occurrence of falls and even deaths. [less ▲]

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See detailAnnual cycle of dimethylsulfoniopropionate (DMSP) and dimethylsulfoxide (DMSO) related to phytoplankton succession in the Southern North Sea
Speeckaert, Gaëlle ULiege; Borges, Alberto ULiege; Champenois, Willy ULiege et al

in Science of the Total Environment (2018), 10.1016/j.scitotenv.2017.11.359

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See detailChronique musicale 2017
Morales, Jorge ULiege

in Seizième siècle (2018), XIV

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See detailStochastic models of disordered mesoporous materials for small-angle scattering analysis and more
Gommes, Cédric ULiege

in Microporous and Mesoporous Materials (2018), 257

Small-angle scattering of either x-rays (SAXS) or neutrons (SANS) is one of the few experimental techniques that can be used to study the structure of porous materials on the entire range from 1 to 100 nm ... [more ▼]

Small-angle scattering of either x-rays (SAXS) or neutrons (SANS) is one of the few experimental techniques that can be used to study the structure of porous materials on the entire range from 1 to 100 nm, which makes it particularly suited for mesoporous materials. Because the information in scattering patterns is a correlation function, models are generally needed to convert data into structurally meaningful information. In this paper, we discuss five stochastic models that capture qualitatively different disordered structures, notably concerning the connectivity and the tortuosity of the phases. The models are two variants of the Boolean model, a dead leaves model, as well as two clipped Gaussian field models. The paper is illustrated with the SAXS analysis of a polymer xerogel, of a fumed silica as well as of a mesoporous alumina, and the fitted models are compared with pore size distributions derived from nitrogen adsorption. In the case of the xerogel and silica it is possible to pinpoint a single model that describes the structure best. In the case of the alumina, however, the scattering cannot discriminate the models. Even so, the models are useful because they enable one to quantitate the structural ambiguity of the SAXS data. [less ▲]

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See detailBone health assessment in older people with or without muscle health impairment.
Locquet, Médéa ULiege; Beaudart, Charlotte ULiege; Bruyère, Olivier ULiege et al

in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2018)

This study investigated the relationship between muscle and bone status in elderly individuals. Our results suggested links between sarcopenia and osteoporosis; impairment in muscle status (i.e., muscle ... [more ▼]

This study investigated the relationship between muscle and bone status in elderly individuals. Our results suggested links between sarcopenia and osteoporosis; impairment in muscle status (i.e., muscle mass, muscle strength, and physical performance) is associated with deterioration in bone mass and texture subsequently leading to an increased risk of fracture. INTRODUCTION: Accumulating evidence has shown associations between sarcopenia and osteoporosis, but existing studies face inconsistencies in the clinical definition of both conditions. Thus, we sought to investigate bone health among older individuals with or without muscle health impairment. METHODS: We conducted an analysis of cross-sectional data available from the Sarcopenia and Physical Impairment with Advancing Age (SarcoPhAge) study. Sarcopenia was diagnosed according to the European Working Group on Sarcopenia in Older People (EWGSOP) (i.e., a low muscle mass plus either low muscle strength or low physical performance). Muscle mass and areal bone mineral density (aBMD) were determined using dual-energy X-ray absorptiometry (DEXA). Muscle strength was assessed using a hand dynamometer, and physical performance was assessed with the Short Physical Performance Battery test. Using the cutoff limits proposed by the EWGSOP, we have classified women in the "low SMI group" when its value was < 5.50 kg/m(2), in the "low muscle strength group" when strength was < 20 kg, and in the "low physical performance group" when SPPB < 8 points. The thresholds of < 7.26 kg/m(2) (for SMI), < 30 kg (for muscle strength), and SPPB < 8 points were used for men. The 10-year fracture risk was obtained using the FRAX(R) tool. Moreover, bone texture was determined using the trabecular bone score (TBS) method. RESULTS: The study sample consisted of 288 older subjects aged 74.7 +/- 5.7 years, and 59.0% of the subjects were women. Sarcopenia was diagnosed in 43 individuals (14.9%), and osteoporosis was diagnosed in 36 subjects (12.5%). Moreover, aBMD values were, most of the time, lower in older men and women with muscle impairment (i.e., low muscle mass, low muscle strength, and low physical performance). For these subjects, we also noted a higher probability of fracture. When comparing bone quality, there were no significant differences in the TBS values between sarcopenic and non-sarcopenic older men and women or between those with low and high muscle mass. However, when controlling for confounders (i.e., age, BMI, number of co-morbidities, smoking status, and nutritional status), TBS values were lower in older women with low muscle strength (p = 0.04) and in older men with low physical performance (p = 0.01). CONCLUSIONS: Our study showed interrelationships between components of sarcopenia and osteoporosis, with older subjects with muscle impairment having poorer bone health. [less ▲]

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See detailNew insights on the Picasso’s Blue Period painting La famille Soler through non-invasive imaging and analytical techniques
Defeyt, Catherine ULiege; Walter, Philippe; Rousselière, Hélène et al

in Studies in Conservation (2018)

The material study of La Famille Soler through non-invasive imaging, molecular, structural and elemental techniques, permitted a relevant re-examination of this singular blue period painting, which is ... [more ▼]

The material study of La Famille Soler through non-invasive imaging, molecular, structural and elemental techniques, permitted a relevant re-examination of this singular blue period painting, which is considered as the earliest Picasso’s version of Le déjeuner sur l’herbe by E. Manet. On the one hand, it was concluded that the underlying landscape painted by Vidal in 1903 referred to Manet’s masterpiece. On the other hand, it was assumed that the cubist sketch undertaken by Picasso in 1912, prior to the current blue background, consists of an uncompleted transformation of Vidal’s landscape into synthetic cubism. Additionally, the main pigments associated to the underlying compositions were successfully identified. [less ▲]

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See detailPhysiological and biochemical parameters: new tools to screen barley root exudates allelopathic potential (*Hordeum vulgare* L. subsp. *vulgare*
Bouhaouel, Imen; Gfeller, Aurélie; Boudabous, Khaoula et al

in Acta Physiologiae Plantarum (2018), 40(2), 1-14

Morphological markers/traits are often used in the detection of allelopathic stress, but optical signals including chlorophyll a fluorescence emission could be useful in developing new screening ... [more ▼]

Morphological markers/traits are often used in the detection of allelopathic stress, but optical signals including chlorophyll a fluorescence emission could be useful in developing new screening techniques. In this context, the allelopathic effect of barley (Hordeum vulgare subsp. vulgare) root exudates (three modern varieties and three landraces) were assessed on the morphological (root and shoot length, biomass accumulation), physiological (Fv/Fm and F0), and biochemical (chlorophyll and protein contents) variables of great brome (Bromus diandrus Roth., syn. Bromus rigidus Roth. subsp. gussonii Parl.). All the measured traits were affected when great brome was grown in a soil substrate in which barley plants had previously developed for 30 days before being removed. The response of receiver plants was affected by treatment with activated charcoal, dependent on barley genotype and on the nature of the growing substrate. The inhibitory effect was lower with the addition of the activated charcoal suggesting the release of putative allelochemicals from barley roots into the soil. The barley landraces were more toxic than modern varieties and their effect was more pronounced in sandy substrate than in silty clay sand substrate. In our investigation, the chlorophyll content and Fv/Fm were the most correlated variables with barley allelopathic potential. These two parameters might be considered as effective tools to quantify susceptibility to allelochemical inhibitors in higher plants. [less ▲]

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See detailBack to materialism Reflections on Marx’s conception of labour, praxis, cooperatives and libertarian socialism
Frère, Bruno ULiege

in International Journal of Politics, Culture and Society (2018), 31(1), 69-94

From Marx to Althusser, the materialist approach has tended to assume that individuals (that is, workers, proletarians and other social actors), unconsciously reproduce the social structures of capitalism ... [more ▼]

From Marx to Althusser, the materialist approach has tended to assume that individuals (that is, workers, proletarians and other social actors), unconsciously reproduce the social structures of capitalism which alienate them. It is assumed that individuals accept the conditions forced upon them and no longer seek to rebel against a world which substantially impoverishes their labour, their spirit and their creativity. In this paper, I will try to show that by dint of favouring almost exclusively Marx's concept of alienation, there is a considerable risk that materialist thought will adopt only a negative path. Whilst I acknowledge Marx’s significance to materialism, I wish to argue that his stance should be combined with that of the anarchist and libertarian French thinker Proudhon. Proudhon has succeeded in presenting a conception of the worker as more than just alienated. Workers can also cooperate and experience a reciprocity seemingly at odds with the character of capitalism. Under Proudhon’s influence materialism takes a positive turn, enabling us to avoid falling into the utopianism that the theory of social economy employs to critique capitalism – a utopianism that renders its critique even less effective than that of Marx. [less ▲]

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See detailHighly Efficient Low-Temperature N-Doped TiO2 Catalysts for Visible Light Photocatalytic Applications
Mahy, Julien ULiege; Cerfontaine, Vincent; Poelman, Dirk et al

in Materials (2018), 11(584),

In this paper, TiO2 prepared with an aqueous sol-gel synthesis by peptization process is doped with nitrogen precursor to extend its activity towards the visible region. Three N-precursors are used: urea ... [more ▼]

In this paper, TiO2 prepared with an aqueous sol-gel synthesis by peptization process is doped with nitrogen precursor to extend its activity towards the visible region. Three N-precursors are used: urea, ethylenediamine and triethylamine. Different molar N/Ti ratios are tested and the synthesis is adapted for each dopant. For urea- and trimethylamine-doped samples, anatase-brookite TiO2 nanoparticles of 6–8 nm are formed, with a specific surface area between 200 and 275 m2·g−1. In ethylenediamine-doped samples, the formation of rutile phase is observed, and TiO2 nanoparticles of 6–8 nm with a specific surface area between 185 and 240 m2·g−1 are obtained. X-ray photoelectron spectroscopy (XPS) and diffuse reflectance measurements show the incorporation of nitrogen in TiO2 materials through Ti–O–N bonds allowing light absorption in the visible region. Photocatalytic tests on the remediation of water polluted with p-nitrophenol show a marked improvement for all doped catalysts under visible light. The optimum doping, taking into account cost, activity and ease of synthesis, is up-scaled to a volume of 5 L and compared to commercial Degussa P25 material. This up-scaled sample shows similar properties compared to the lab-scale sample, i.e., a photoactivity 4 times higher than commercial P25. [less ▲]

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See detailThe Far-wanderer: Proclus on the Transmigration of the Soul
Fortier, Simon ULiege

in Classical Quarterly (2018)

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See detailPhase Change Materials for Non-Volatile Memory devices: From Technological Challenges to Materials Science Issues
Noé, Pierre; Vallée, Christophe; Hippert, Francoise et al

in Semiconductor Science and Technology (2018)

Abstract Chalcogenide Phase-Change Materials (PCMs), such as Ge-Sb-Te alloys, are showing outstanding properties, which has led to their successful use for a long time in optical memories (DVDs) and ... [more ▼]

Abstract Chalcogenide Phase-Change Materials (PCMs), such as Ge-Sb-Te alloys, are showing outstanding properties, which has led to their successful use for a long time in optical memories (DVDs) and, recently, in non-volatile resistive memories. The latter, known as Phase-Change Material memories or Phase-Change Random Access Memories (PCRAMs), are the most promising candidate among emerging Non-Volatile Memory (NVM) technologies to replace the current FLASH memories at CMOS technology nodes under 28 nm. Chalcogenide PCMs exhibit fast and reversible phase transformations between crystalline and amorphous states with very different transport and optical properties leading to a unique set of features for PCRAMs, such as fast programming, good cyclability, high scalability, multi-level storage capability and good data retention. Nevertheless, PCM memory technology has to overcome several challenges to definitively invade the NVM market. In this review paper we examine the main technological challenges that PCM memory technology must face and we illustrate how new memory architecture, innovative deposition methods and PCM composition optimization can contribute to further improvements of this technology. In particular, we examine how to lower the programming currents and increase data retention. Scaling down PCM memories for large scale integration means incorporation of the phase-change material into more and more confined structures and raises material science issues to understand interface and size effects on crystallization. Other material science issues are related to the stability and ageing of the amorphous state of phase-change materials. The stability of the amorphous phase, which determines data retention in memory devices, can be increased by doping the phase-change material. Ageing of the amorphous phase leads to a large increase of the resistivity with time (resistance drift), which has hindered up-to-now the development of ultra-high multilevel storage devices. A review of the current understanding of all these issues is provided from a material science point of view. [less ▲]

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See detailAlternatives for the bedside Schwartz equation to estimate glomerular filtration rate in children.
Pottel, Hans ULiege; Dubourg, Laurence; Goffin, Karolien et al

in Advances in Chronic Kidney Disease (2018), 25(1), 57-66

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See detailA closer look at children’s metacognitive skills: The case of the distinctiveness heuristic
Geurten, Marie ULiege; Meulemans, Thierry ULiege; Willems, Sylvie ULiege

in Journal of Experimental Child Psychology (2018), 172

The primary aim of this study was to document the developmental course of distinctiveness effects throughout childhood. Specifically, we examined whether the reduction in false recognition rates that is ... [more ▼]

The primary aim of this study was to document the developmental course of distinctiveness effects throughout childhood. Specifically, we examined whether the reduction in false recognition rates that is traditionally observed in children after distinctive encoding could be explained not only by enhanced discrimination between studied and new items but also by the implementation of a conservative response criterion resulting from the use of metacognitive expectations about the quality of memories (i.e., distinctiveness heuristic). Two experiments were conducted in which children aged 4–5, 6–7, and 8–9 years old were asked to study a set of items presented either in pictorial (distinctive) or in word (less distinctive) form. In Experiment 1, pictures and words were displayed in two separate lists, a design that is supposed to favor reliance on the distinctiveness heuristic. In Experiment 2, the two types of stimuli were presented within the same list, a design that is supposed to make using the metacognitive heuristic ineffective. Overall, Experiments 1 and 2 provide evidence that children as young as 4 rely on the distinctiveness heuristic to guide their memory decisions, resulting in a reduction in the false recognition rate when items are presented using a pure-list design (Experiment 1), but not when they are presented using a mixed-list design (Experiment 2). The implications of these findings for our understanding of the development of metacognition and the involvement of metacognitive skills in children’s memory performance are discussed. [less ▲]

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See detaille cas clinique du mois: découverte fortuite d’anomalies génétiques maternelles lors du test prénatal non invasif
Leonard, Françoise; Gueben, Renaud; Gueben, Robin et al

in Revue Médicale de Liège (2018), 73(1),

Le test prénatal non invasif (TPNI) a été intro- duit récemment dans notre pratique clinique. La sensibilité et la spécificité de cette méthode pour le dépistage des principales aneuploïdies ... [more ▼]

Le test prénatal non invasif (TPNI) a été intro- duit récemment dans notre pratique clinique. La sensibilité et la spécificité de cette méthode pour le dépistage des principales aneuploïdies fœtales est de l’ordre de 99%. À cause de l’existence de faux positifs et de faux négatifs, cette technique reste un test de dépistage, non de diagnos- tic. Les résultats discordants s’expliquent par la méthode elle-même qui analyse la totalité de l’ADN libre circulant dans le sang maternel : l’ADN fœtal provenant de la lyse des cellules trophoblastiques, mais aussi l’ADN d’origine maternelle. La mosaïque confinée au placenta est la cause principale des faux positifs décrits dans la littérature. Plus rarement, le TPNI peut mettre en évidence des anomalies maternelles. Nous rapportons le cas de deux patientes por- teuses d’une anomalie cytogénétique révélée par le TPNI : une microduplication 22q11.2 et une anomalie des chromosomes sexuels [less ▲]

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See detailInteractions between Zn2+ or ZnO with TiO2 to produce an efficient photocatalytic, superhydrophilic and aesthetic glass
Léonard, Géraldine ULiege; Pàez Martinez, Carlos ULiege; Ramirez, Alfonso et al

in Journal of Photochemistry and Photobiology A : Chemistry (2018), 350

Zinc was coupled with titanium dioxide using different methods. SiO2 and Zn-SiO2 doped TiO2 films, on the one hand, and Zn doped TiO2 on the other hand, have been produced using controlled sol-gel ... [more ▼]

Zinc was coupled with titanium dioxide using different methods. SiO2 and Zn-SiO2 doped TiO2 films, on the one hand, and Zn doped TiO2 on the other hand, have been produced using controlled sol-gel processes by alcoholic, cogelation and aqueous ways. From these syntheses, films were deposited on soda lime glass. These samples were compared to ZnO samples but also to bilayer samples constituting one layer of TiO2 and one layer of ZnO. The physico-chemical properties of the films were characterized by grazing-incidence X-ray diffraction, profilometry and UV-Vis absorption analyses. The photocatalytic activity has been evaluated from the degradation of methylene blue under UV-A light, from the degradation of p-nitrophenol under visible light and from the degradation of H2O2 under halogen light (UV-A + visible light). Superhydrophilicity was evaluated from contact angle measurement after UV exposition and also from hysteresis effects. Finally, a haze measurement was performed to evaluate the impact of the coating on the aesthetic property of the coated glass. Aqueous films have better photocatalytic activity and superhydrophilicity than samples from alcoholic synthesis. The crystallization of the sample appears to be one key factor: alcoholic films required calcination to ensure the crystallization of TiO2, but the alkali migration from the glass support prevents this crystallisation, while aqueous synthesis promotes crystallized particles at low temperatures without alkali interference. It appears that the relative activity from one sample to another depends on the nature of the illumination and on the nature of the molecule to be degraded. Nevertheless, the sample with ZnO layer deposited on first TiO2 layer (ZnO 500 Alc/TiO2 100 AQ) composite is found to be the best sample, maintaining a high hydrophilicity similar to TiO2 and a good activity. [less ▲]

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See detailThe Creative Economy as a Versatile Policy Script: Exploring the Role of Competing International Organizations
Vlassis, Antonios ULiege; De Beukelaer, Christiaan

in Media, Culture & Society (2018)

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See detailThe dorsal attention network reflects both encoding load and top-down control during working memory
Majerus, Steve ULiege; Péters, Frédéric; Bouffier, Marion ULiege et al

in Journal of Cognitive Neuroscience (2018), 30

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See detailBasic mechanisms in the laser control of non-Markovian dynamics
Puthumpally-Joseph, Raijumon; Mangaud, Etienne; Chevet, Vincent et al

in Physical Review A (2018), 97

Referring to a Fano-type model qualitative analogy we develop a comprehensive basic mechanism for the laser control of the non-Markovian bath response and fully implement it in a realistic control scheme ... [more ▼]

Referring to a Fano-type model qualitative analogy we develop a comprehensive basic mechanism for the laser control of the non-Markovian bath response and fully implement it in a realistic control scheme, in strongly coupled open quantum systems. Converged hierarchical equations of motion are worked out to numerically solve themaster equation of a spin-boson Hamiltonian to reach the reduced electronic density matrix of a heterojunction in the presence of strong terahertz laser pulses. Robust and efficient control is achieved increasing by a factor of 2 the non-Markovianity measured by the time evolution of the volume of accessible states. The consequences of such fields on the central system populations and coherence are examined, putting the emphasis on the relation between the increase of non-Markovianity and the slowing down of decoherence processes. [less ▲]

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See detailPhénoménologie et sémiotique : deux approches complémentaires du sens
Badir, Sémir ULiege

in Acta Structuralica (2018), Special Issue 1

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See detailHyper-réflexivité et perspective en première personne : un apport décisif de la psychopathologie phénoménologique contemporaine à la compréhension de la schizophrénie
Englebert, Jérôme ULiege; Stanghellini, Giovanni; Valentiny, Caroline et al

in Evolution Psychiatrique (2018), 83(1), 77-85

Objectives: This paper aims to summarize the hypothesis, which originates in the field of phenomenological psychopathology, of schizophrenic hyperreflexivity, and to discuss the methodological context ... [more ▼]

Objectives: This paper aims to summarize the hypothesis, which originates in the field of phenomenological psychopathology, of schizophrenic hyperreflexivity, and to discuss the methodological context enabling these highly subjective manifestations to emerge. Starting from the seminal hypothesis developed by contemporary psychopathology, that the schizophrenic patients appear to experience a consciousness that finds itself being forced to question phenomena which should be intuitively self-evident, the idea of this present paper is to complete the usual interpretation of schizophrenia as deficit by the hypothesis of an excess functioning of consciousness. Methods: First-person perspective is a qualitative approach completing third-person interpretation, traditional in the field of psychiatry – which consists in the attribution, from an external position, of clinical signs noted independently of the perception expressed by the patient. This first-person perspective focuses on the subjective experience expressed by the individual. To understand schizophrenia according to this perspective, the words of several schizophrenic patients have been collected as part of a clinical device. We used the EASE scale (Examination of Anomalous Self-Experience) with this aim in mind. This scale offers a phenomenologically oriented semi-structured exploration of a set of difficulties revealing anomalies of subjective experience, considered as troubles of self-awareness. EASE has been developed on the basis of self-descriptions by patients suffering from schizophrenic spectrum troubles. This tool allows the co-construction of a language between patient and clinician, focused on the patient’s particular experience and the unique phenomena he endures. Results: Besides the hyperreflexivity phenomena, the qualitative analysis of collected descriptions highlight two important features of schizophrenic being-in-the-world. First a problem of common sense, which addresses the issue of intersubjectivity and the opportunity, for schizophrenic patients, to share a social world. Then the existence of an intercorporeality trouble, since the schizophrenic hyperreflexivity experiences are accompanied by a loss of “common body”, body being the scene where intersubjectivity is performed. Employing EASE, and the ensuing first-person perspective, is relevant in a psychotherapeutic approach; on one hand in the process of acknowledgement of the disease (which has to be made by the patient as well as by the clinician), on the other hand in the communication with families of schizophrenic patients. Conclusions: The phenomenological interpretation offered by the application of a first-person perspective in the understanding of schizophrenic patients experience, as well as the interest showed in the hyperreflexivity phenomenon, suggest an outlook of schizophrenia which isn’t reduced to a deficit interpretation anymore (without denying the latter), and which uncovers not a weakening, but a surprising intensification of consciousness. [less ▲]

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See detailThe complexity of environmental migration: case of the returned Burkinabe fulani breeders from Bouna Department in Ivory Coast to Noumbiel Province in Burkina Faso
Tomety, Yaovi Djivénou; Puškárovà, Paula; Gemenne, François ULiege et al

in Journal of International Relations (2018), 16(1), 22-38

The issue of environmental migration starts to involve growing number of scholars and policymakers all around the world. Conventionally, environmental degradation is not a sole reason that drives people ... [more ▼]

The issue of environmental migration starts to involve growing number of scholars and policymakers all around the world. Conventionally, environmental degradation is not a sole reason that drives people to move but rather it goes hand-in-hand with other political and socio-economic factors. In March 2016, an inter-communal conflict arose between Lobi farmers and Burkinabe Fulani herders who had settled in Bouna department in the northeast of Ivory Coast after leaving Burkina Faso following the great drought in 1970s. This conflict that appears to be born along a banal fact of pillaging the Lobi farmers' fields by the cattle of Burkinabe Fulani herders had serious consequences: numerous injuries, several casualties, capital destruction, and economic losses. Eventually, the conflict led to displacement of few thousand people to the province of Noumbiel in Burkina Faso. The analysis of the roots of this massive displacement points to the growing local demand for natural resources and to the management of agricultural lands what got aggravated along social issues of chieftaincy among different ethnic groups in the Bouna area. The increase in the area of agricultural land has led to shrinkages in the area of rangelands and the degradation of forest resources, thus reducing pasture acreage of cattle herds. Although clashes between stockbreeders and agriculturists had been taking place in the neighbourhood for many years, the situation appeared to escalate up to the point of prompting people to move for the first time. Even though the displaced people in this case are considered returnees to their home country, the years of staying in Ivory Coast destroyed almost all social and economic linkages in their home country. The situation led to humanitarian crisis marked by limited access to UN support since the status of returnees did not qualify for refugee. The support was provided by local Burkinabe government and NGOs. [less ▲]

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See detailEffects of agricultural land use on fluvial carbon dioxide, methane and nitrous oxide concentrations in a large European river, the Meuse (Belgium)
Borges, Alberto ULiege; Darchambeau, François ULiege; Lambert, Thibault ULiege et al

in Science of the Total Environment (2018), 610–611

We report a data-set of CO2, CH4, and N2O concentrations in the surface waters of the Meuse river network in Belgium, obtained during four surveys covering 50 stations (summer 2013 and late winter 2013 ... [more ▼]

We report a data-set of CO2, CH4, and N2O concentrations in the surface waters of the Meuse river network in Belgium, obtained during four surveys covering 50 stations (summer 2013 and late winter 2013, 2014 and 2015), from yearly cycles in four rivers of variable size and catchment land cover, and from 111 groundwater samples. Surface waters of the Meuse river network were over-saturated in CO2, CH4, N2O with respect to atmospheric equilibrium, acting as sources of these greenhouse gases to the atmosphere, although the dissolved gases also showed marked seasonal and spatial variations. Seasonal variations were related to changes in freshwater discharge following the hydrological cycle, with highest concentrations of CO2, CH4, N2O during low water owing to a longer water residence time and lower currents (i.e. lower gas transfer velocities), both contributing to the accumulation of gases in the water column, combined with higher temperatures favourable to microbial processes. Inter-annual differences of discharge also led to differences in CH4 and N2O that were higher in years with prolonged low water periods. Spatial variations were mostly due to differences in land cover over the catchments, with systems dominated by agriculture (croplands and pastures) having higher CO2, CH4, N2O levels than forested systems. This seemed to be related to higher levels of dissolved and particulate organic matter, as well as dissolved inorganic nitrogen in agriculture dominated systems compared to forested ones. Groundwater had very low CH4 concentrations in the shallow and unconfined aquifers (mostly fractured limestones) of the Meuse basin, hence, should not contribute significantly to the high CH4 levels in surface riverine waters. Owing to high dissolved concentrations, groundwater could potentially transfer important quantities of CO2 and N2O to surface waters of the Meuse basin, although this hypothesis remains to be tested. [less ▲]

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See detailThe evolutionary history of polycotylid plesiosaurians
Fischer, Valentin ULiege; Benson, Roger B.J.; Druckenmiller, Patrick et al

in Royal Society Open Science (2018), 5(172177), 1-26

Polycotylidae is a clade of plesiosaurians that appeared during the Early Cretaceous and became speciose and abundant early in the Late Cretaceous. However, this radiation is poorly understood. Thililua ... [more ▼]

Polycotylidae is a clade of plesiosaurians that appeared during the Early Cretaceous and became speciose and abundant early in the Late Cretaceous. However, this radiation is poorly understood. Thililua longicollis from the Middle Turonian of Morocco is an enigmatic taxon possessing an atypically long-neck and, as originally reported, a series of unusual cranial features that cause unstable phylogenetic relationships for polycotylids. We reinterpret the holotype specimen of Thililua longicollis and clarify its cranial anatomy. Thililua longicollis possesses an extensive, foramina-bearing jugal, a premaxilla-parietal contact, and carinated teeth. Phylogenetic analyses of a new cladistic dataset based on first hand observation of most polycotylids, recovers Thililua and Mauriciosaurus as successive lineages at the base of the earliest Late Cretaceous polycotyline radiation. A new dataset summarizing the Bauplan of polycotylids reveal that their radiation produced an early burst of disparity during the Cenomanian-Turonian interval, with marked plasticity in relative neck length, but this did not arise as an ecological release following the extinction of ichthyosaurs and pliosaurids. This disparity vanished during and after the Turonian, which is consistent with a model of 'early experimentation/late constraint'. Two polycotylid clades, Occultonectia clade nov. and Polycotylinae, survived up to the Maastrichtian, but with low diversity. [less ▲]

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See detailContrasting cadmium resistance strategies in two metallicolous populations of Arabidopsis halleri
Corso, Massimiliano; Schvartzman Echenique, Maria Sol ULiege; Guzzo, Flavia et al

in New Phytologist (2018)

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See detailTechnical and economic optimization of subcritical, wet expansion and transcritical Organic Rankine Cycle (ORC) systems coupled with a biogas power plant
Dumont, Olivier ULiege; Dickes, Rémi ULiege; De Rosa, M. et al

in Energy Conversion and Management (2018), 157

Generally, >40% of the useful energy (cooling engine and exhaust gases) are wasted by a biogas power plant through the cooling radiator and the exhaust gases. An efficient way to convert this waste heat ... [more ▼]

Generally, >40% of the useful energy (cooling engine and exhaust gases) are wasted by a biogas power plant through the cooling radiator and the exhaust gases. An efficient way to convert this waste heat into work and eventually electricity is the use of an organic Rankine cycle (ORC) power system. Over the last few years, different architectures have been widely investigated (subcritical, wet expansion and trans-critical). Despite the promising performances, realistic economic and technical constraints, also related to the application, are required for a meaningful comparison between ORC technologies and architectures. Starting from the limited literature available, the aim of the present paper is to provide a methodology to compare sub-critical, trans-critical and wet expansion cycles and different types of expanders (both volumetric and turbomachinery) from both technical and economic point of view, which represent one of the main novel aspects of the present work. In particular, the paper focuses on the thermo-economic optimization of an ORC waste heat recovery unit for a 500 kWe biogas power plant located in a detailed regional market, which was not investigated yet. By means of a genetic algorithm, the adopted methodology optimizes a given economic criteria (Pay-Back Period, Net Present Value, Profitability Index and Internal Rate of Return) while respecting technical constraints (expander limitations) and thermodynamic constraints (positive pinch points in heat exchangers, etc.). The results show that optimal ORC solutions with a potential of energy savings up to 600 MWh a year and with a pay-back period lower than 3 years are achievable in the regional market analysed. © 2017 Elsevier Ltd [less ▲]

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See detailLa révolution vidéo en Afrique subsaharienne. Nigéria, Ethiopie et Côte d'Ivoire
Jedlowski, Alessandro ULiege

in Sociétés politiques comparées (2018), 43

Avec l’introduction de technologies analogiques et (plus tard) numériques, de nombreux pays d’Afrique subsaharienne ont vu l’émergence et la croissance rapide d’industries audiovisuelles commerciales ... [more ▼]

Avec l’introduction de technologies analogiques et (plus tard) numériques, de nombreux pays d’Afrique subsaharienne ont vu l’émergence et la croissance rapide d’industries audiovisuelles commerciales produisant des fi lms en format vidéo. L’industrie nigériane, Nollywood, est le cas d’étude qui a suscité le plus d’intérêt, contribuant à la formulation d’un modèle analytique qui a infl uencé notre compréhension d’autres exemples de production en cours sur le continent. Cet article propose une analyse comparative de l’histoire de la production vidéo dans trois pays d’Afrique subsaharienne (Nigéria, Ethiopie et Côte d’Ivoire), afi n de complexifi er notre approche de la production vidéo africaine au-delà du modèle de Nollywood. À partir des documents recueillis lors de recherches de terrain ethnographiques menées dans chacun de ces pays, il offre une contribution originale au débat actuel sur l’impact des technologies analogiques et numériques sur la transformation du cinéma africain, en mettant en évidence le rôle des contextes politique, économique et infrastructurel locaux sur le développement des industries vidéo en Afrique subsaharienne. [less ▲]

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See detailEffect of muscle type, aging technique, and aging time on oxidative stability and antioxidant capacity of beef packed in high-oxygen atmosphere
Didimo Imazaki, Pedro Henrique ULiege; Douny, Caroline ULiege; Elansary, Mahmoud ULiege et al

in Journal of Food Processing and Preservation (2018)

This study aimed to compare the effect of muscle type, aging technique, and aging time on the oxidative stability of beef packed in high-oxygen atmosphere. Longissimus thoracis et lumborum (LTL) and ... [more ▼]

This study aimed to compare the effect of muscle type, aging technique, and aging time on the oxidative stability of beef packed in high-oxygen atmosphere. Longissimus thoracis et lumborum (LTL) and rectus femoris (RF) muscles from Belgian Blue cows were vacuum aged (VA) or aged on the carcass (CA) for 7 days. Then, they were stored under vacuum at -1°C for up to 28 days. At different times, samples were repackaged under a high-oxygen atmosphere and stored at 4°C for 7 days. The following parameters were evaluated: color, metmyoglobin %, fat content, fatty acid profile, lipid oxidation, metmyoglobin reducing activity (MRA), a-tocopherol content, and antioxidant enzymes activity. The sensitivity of meat to oxidation was influenced by muscle type (RF>LTL), aging technique (VA>CA), aging time (35>21>7 days), and display time (7>0 days), and could be related to MRA and antioxidant enzymes activity. [less ▲]

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See detailAutosomal recessive primary microcephaly due to ASPM mutations: An update.
Letard, Pascaline; Drunat, Severine; Vial, Yoann et al

in Human Mutation (2018)

Autosomal recessive microcephaly or MicroCephaly Primary Hereditary (MCPH) is a genetically heterogeneous neurodevelopmental disorder characterized by a reduction in brain volume, indirectly measured by ... [more ▼]

Autosomal recessive microcephaly or MicroCephaly Primary Hereditary (MCPH) is a genetically heterogeneous neurodevelopmental disorder characterized by a reduction in brain volume, indirectly measured by an occipitofrontal circumference (OFC) 2 standard deviations or more below the age- and sex-matched mean (-2SD) at birth and -3SD after 6 months, and leading to intellectual disability of variable severity. The Abnormal SPindle-like Microcephaly gene (ASPM), the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), encodes ASPM, a protein localized at the centrosome of apical neuroprogenitor cells and involved in spindle pole positioning during neurogenesis. Loss-of-function mutations in ASPM cause MCPH5, which affects the majority of all MCPH patients worldwide. Here, we report 47 unpublished patients from 39 families carrying 28 new ASPM mutations, and conduct an exhaustive review of the molecular, clinical, neuroradiological and neuropsychological features of the 282 families previously reported (with 161 distinct ASPM mutations). Furthermore, we show that ASPM-related microcephaly is not systematically associated with intellectual deficiency and discuss the association between the structural brain defects (strong reduction in cortical volume and surface area) that modify the cortical map of these patients and their cognitive abilities. This article is protected by copyright. All rights reserved. [less ▲]

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See detailHigh dose chemotherapy and autologous stem cell transplantation in nodular lymphocyte-predominant Hodgkin lymphoma: A retrospective study by the European society for blood and marrow transplantation-lymphoma working party
Akhtar, S.; Montoto, S.; Boumendil, A. et al

in American Journal of Hematology (2018), 93(1), 40-46

Whilst autologous stem cell transplantation (auto-SCT) is considered standard of care for relapsed/refractory classical Hodgkin lymphoma, the role of auto-SCT in nodular lymphocyte-predominant Hodgkin ... [more ▼]

Whilst autologous stem cell transplantation (auto-SCT) is considered standard of care for relapsed/refractory classical Hodgkin lymphoma, the role of auto-SCT in nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is not well defined due to limited data. We report the first study on auto-SCT for NLPHL with a larger cohort. Eligible for this retrospective registry study were patients reported to the EBMT between 2003 and 2013, aged 18 or older with relapsed/refractory NLPHL who underwent first auto-SCT with disease chemosensitive to salvage therapy. NLPHL transformed to diffuse large B cell lymphoma were excluded. Sixty patients (83% male; median age 40 years) met the eligibility criteria. The median time between diagnosis and transplant was 21 months (IQR 13–58), and the median number of prior treatment lines was 2 (range 1–5), including rituximab in 63% of the patients. At auto-SCT, 62% of the patients were in complete remission (CR) and 38% in partial remission. Seventy-two percent of the patients received BEAM as high-dose therapy. With a median follow-up of 56 months (range 3–105), 5-year progression-free and overall survival (OS) were 66% and 87%, respectively. Univariate comparisons considering age, time from diagnosis to transplant, prior chemotherapy lines, and prior rituximab use failed to identify significant predictors for any survival endpoint except for being in CR at the time of auto-SCT (vs PR, P =.049) for OS. Auto-SCT in patients with relapsed/refractory NLPHL who are sensitive to salvage therapy gives excellent disease control and long-term survival independent of the time interval between diagnosis and transplant. © 2017 Wiley Periodicals, Inc. [less ▲]

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