References of "Scientific journals"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailGenomic screening in family-based association testing
Van Steen, Kristel ULiege; McQueen, M.; Herbert, A. et al

in Genetic Epidemiology (2004), 27

Detailed reference viewed: 12 (5 ULiège)
Full Text
Peer Reviewed
See detailEffects of an experimental Trypanosoma congolense infection on the reproductive performance of West African Dwarf goats.
Faye, Dethie; Sulon, Joseph ULiege; Kane, Yaghouba et al

in Theriogenology (2004), 62(8), 1438-51

Thirty-six West African Dwarf (WAD) goats were used to assess the effects of an experimental Trypanosoma congolense infection on their reproductive system. Estrous cycles were synchronised and when ... [more ▼]

Thirty-six West African Dwarf (WAD) goats were used to assess the effects of an experimental Trypanosoma congolense infection on their reproductive system. Estrous cycles were synchronised and when confirmed pregnant (n = 31), the does were randomly allocated into control and trypanosome-infected groups. After infection, the animals were carefully observed till parturition. Trypanosome infection caused an increase of rectal temperature, a significant drop in PCV (infected: 23.3 +/- 0.3%; control: 28.5 +/- 0.4%; P < 0.0001) and abortions in 27.8% of the infected does. Kids born from infected does had a lower birth weight than kids born from control goats (0.9 +/- 0.1 kg versus 1.6 +/- 0.1 kg; P < 0.0001). Eight out of 13 kids (61.5%) that were born alive from infected does died during their first week of life. Plasma pregnancy-associated glycoprotein (PAG) and progesterone concentrations were lower in the infected animals than in the controls. In general, PAG concentration in does which aborted dropped before abortion. Our results revealed that artificial T. congolense infection affected reproductive performance of WAD goats with abortions, premature births and perinatal losses being observed. Neither transplacental transmission of T. congolense nor histopathological lesions of the placenta could be demonstrated. [less ▲]

Detailed reference viewed: 27 (0 ULiège)
Full Text
Peer Reviewed
See detailImprovement Of Spray Deposit Homogeneity Using A Pwm Spray Controller To Compensate Horizontal Boom Speed Variations
Lebeau, Frédéric ULiege; El Bahir, L.; Destain, Marie-France ULiege et al

in Computers and Electronics In Agriculture (2004), 43(2),

Longitudinal spray distribution is mainly affected by the horizontal speed variations of the nozzles. Manufacturers classically try to reduce unwanted nozzles movements using horizontal boom suspension ... [more ▼]

Longitudinal spray distribution is mainly affected by the horizontal speed variations of the nozzles. Manufacturers classically try to reduce unwanted nozzles movements using horizontal boom suspension but these methods have performance and price limitations. This paper describes a spray controller aiming to compensate the effect of the horizontal boom movements on the spray deposits homogeneity. The controller is based on three main components: a control law describing the relationship between nozzle speed, nozzle flow and spray deposit; a real time measurement of the boom horizontal speed variations using micro-machined capacitive accelerometers, and pulse width modulation (PWM) nozzle flow actuators. To assess the feasibility of such a controller, a single nozzle prototype was developed and tested in the laboratory, using a nigrosine solution. Spray coverage was measured using image analysis for field representative nozzle speed variations. The spray coverage uniformity using the controller showed about 51% compensation of the variations observed without it. [less ▲]

Detailed reference viewed: 74 (10 ULiège)
Full Text
Peer Reviewed
See detailHotspots, complementarity or representativeness? Designing optimal small-scale reserves for biodiversity conservation
Kati, V.; Devillers, P.; Dufrêne, Marc ULiege et al

in Biological Conservation (2004), 120(4), 471-480

Reserve networks are a major tool of ecological management aiming at biodiversity conservation. Maximizing the number of species conserved with the minimum land sacrifice is a primary requirement in ... [more ▼]

Reserve networks are a major tool of ecological management aiming at biodiversity conservation. Maximizing the number of species conserved with the minimum land sacrifice is a primary requirement in reserve design. In this study, we examine the efficiency of five different scenarios to conserve: (i) the biodiversity of one target group and (ii) the overall biodiversity of an area. The study was conducted in Dadia Reserve, in northern Greece. Six groups of species were selected to represent its biodiversity: woody plants, orchids, Orthoptera, aquatic and terrestrial herpetofauna, and small terrestrial birds. The scenarios examined represent different conservation approaches to select network sites. For each approach, the starting point was one of the above six groups of species, considered as the target group. In scenario A, which reflects the hotspot approach, the sites richest in species are selected. Scenario B selects the sites most complementary in terms of species richness. The next two scenarios use the principle of environmental representativeness, expressed in terms of habitat (scenario C) or vegetation (scenario D). Under scenario E, sites forming the network are selected at random. The rank of scenarios in terms of preserving the species of the target group was always B>A>C>D>E, irrespective of the group considered as target group. Their rank, when preservation of the total biodiversity was the issue, was B, A>C, D>E. © 2004 Elsevier Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 23 (4 ULiège)
Full Text
Peer Reviewed
See detailCausale connectieven in het Leerdercorpus Nederlands
Degand, Liesbeth; Perrez, Julien ULiege

in N/F. Tijdschrift van de Association des néerlandistes de Belgique francophone (2004), 4

Detailed reference viewed: 50 (1 ULiège)
Full Text
Peer Reviewed
See detailResidence time in a semi-enclosed domain from the solution of an adjoint problem
Delhez, Eric ULiege; Heemink, Arnold W.; Deleersnijder, Eric

in Estuarine Coastal & Shelf Science (2004), 61(4), 691-702

The residence time measures the time spent by a water parcel or a pollutant in a given water body and is therefore a widely used concept in environmental studies. While many previous studies rely on ... [more ▼]

The residence time measures the time spent by a water parcel or a pollutant in a given water body and is therefore a widely used concept in environmental studies. While many previous studies rely on severe hypotheses (assuming stationarity of the flow and/or neglecting diffusion) to evaluate the residence time, the paper introduces a general method for computing the residence time and/or the mean residence time without such simplifying hypotheses. The method is based on the resolution of an adjoint advection-diffusion problem and is therefore primarily meant to be used with numerical models. The method and its implications are first introduced using a simplified one-dimensional analytical model. The approach is then applied to the diagnostic of the three-dimensional circulation on the Northwest European Continental Shelf. (C) 2004 Elsevier Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 59 (18 ULiège)
Full Text
Peer Reviewed
See detailCase studies in measurement of random incidence scattering coefficients
Vorländer, Michael; Embrechts, Jean-Jacques ULiege; De Geetere, Lieven et al

in Acta Acustica United With Acustica (2004), 90(5, SEP-OCT), 858-867

In this work measurements of random-incidence scattering coefficients in three laboratories are compared. The sample geometry is sinusoidal. These surfaces are geometrically identical, but they were ... [more ▼]

In this work measurements of random-incidence scattering coefficients in three laboratories are compared. The sample geometry is sinusoidal. These surfaces are geometrically identical, but they were constructed in different scales. So far, measurements of this kind were performed only in scale models. Using turntables in real sample size was hardly considered possible. One result of general importance is that measurements are indeed possible in real-scale reverberation rooms with turntables of 3 m diameter. There are only small differences between the real-scale and model-scale results. Some variations of the standard procedure were tested and the uncertainties identified: mounting of the sample, connection or sealing between sample and base plate, way of rotating the sample, air absorption and time variances. The results presented can be regarded as guidelines for application of ISO/DIS 17497-1. [less ▲]

Detailed reference viewed: 51 (4 ULiège)
Full Text
Peer Reviewed
See detailL'ostéodensitométrie
Devogelaer, Jean-Pierre; Reginster, Jean-Yves ULiege

in Ortho-Rhumato (2004), 2

Detailed reference viewed: 12 (2 ULiège)
Full Text
Peer Reviewed
See detailMorphology, growth and modelling of bone tissue
Toppets, Vinciane ULiege; Pastoret, V.; De Behr, V. et al

in Annales de Médecine Vétérinaire (2004), 148(1), 1-13

Bone is an essential part of the squeletton. Besides its mechanic properties, bone has an important role in metabolism regulation because it acts as a reservoir for the storage of minerals essential to ... [more ▼]

Bone is an essential part of the squeletton. Besides its mechanic properties, bone has an important role in metabolism regulation because it acts as a reservoir for the storage of minerals essential to provide homeostasy. This article describes bone morphology and different ways of classification of this tissue. It gives the composition of organic and mineral extracellular bone matrix, underlines the dynamic character of bone tissue, details the cellular morphology and the metabolism of the elements acting on the synthesis/resorption mechanisms : osteoprogenitor cells, osteoblasts, osteocyts and osteoclasts. It relates the histogenesis of bone tissue and develops the different types of ossification: intramembranous, periostic, endochondral and osteonal remodeling. The last part of this article describe some dietetary and hormonal influences on bone tissue. [less ▲]

Detailed reference viewed: 67 (12 ULiège)
Full Text
Peer Reviewed
See detailSegregation of the bulk blend fertilizers
Miserque, Olivier; Pirard, Eric ULiege

in Chemometrics and Intelligent Laboratory Systems (2004), 74(1), 215-224

Bulk blend fertilizers are a mixture of different kinds of fertilizers in order to obtain a predicted N-P-K chemical composition. Although this production method has some advantages, segregation appears ... [more ▼]

Bulk blend fertilizers are a mixture of different kinds of fertilizers in order to obtain a predicted N-P-K chemical composition. Although this production method has some advantages, segregation appears at different stages, from the production to the final spreading on the field. An experiment has been implemented to predict and quantify the influence of some physical properties on the occurrence of segregation. The principle was to blend two fertilizers having identical physical properties except for one, such as size, shape or density and to measure the segregation of the blend following various operations, such as filling or emptying a container. Results show that the spread of the fragment size distribution has a big influence on the segregation of the generated heap. In order to reduce this phenomenon, the granulometric spread index (GSI) [(d(84)-d(16))/2d(50)] must be smaller than 10. Other properties don't seem to have an influence. The granulometric segregation can lead to a chemical heterogeneity. The absolute sum of the difference between d(16) and d(84) must be limited around 0.5 mm. Above this value, the chemical segregation begins to be excessive. It seems also that if there is a limited difference in size for the components, the chemical segregation is amplified if the density of the fertilizer with the biggest particles is lower. It is not the case for the difference in shape. (C) 2004 Elsevier B.V. All rights reserved. [less ▲]

Detailed reference viewed: 188 (16 ULiège)
Full Text
Peer Reviewed
See detailSimian immunodeficiency virus Vpr/Vpx proteins kill bystander noninfected CD4+ T-lymphocytes by induction of apoptosis
Bouzar, Amel ULiege; Villet, S.; Morin, T. et al

in Virology (2004)

Detailed reference viewed: 16 (0 ULiège)
Full Text
Peer Reviewed
See detailLe BLV: un modele d'etude pour les leucemies humaines.
Willems, Luc ULiege

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (2004), 159(10-12),

Detailed reference viewed: 14 (3 ULiège)
Full Text
Peer Reviewed
See detailPolymorphisms in Type-II SH2 domain-containing Inositol 5-Phosphatase (INPPL1, SHIP2) are Associated with Physiological Abnormalities of the Metabolic Syndrome
Kaisaki, P. J.; Delépine, M.; Woon, P. Y. et al

in Diabetes (2004), 53

Type II SH2 domain-containing inositol 5-phosphatase (INPPL1, or SHIP2) plays an important role in the control of insulin sensitivity. INPPL1 mutations affecting gene function have been found in rat ... [more ▼]

Type II SH2 domain-containing inositol 5-phosphatase (INPPL1, or SHIP2) plays an important role in the control of insulin sensitivity. INPPL1 mutations affecting gene function have been found in rat models of type 2 diabetes and hypertension and in type 2 diabetic patients. We investigated the influence of nucleotide variation in INPPL1 on components of the metabolic syndrome. Following comprehensive resequencing of the gene, we genotyped 12 informative polymorphisms in 1,304 individuals from 424 British type 2 diabetes families that were characterized for several metabolic phenotypes. We have found highly significant associations of single nucleotide polymorphisms (SNPs) and haplotypes of INPPL1 with hypertension as well as with other components of the metabolic syndrome. In a cohort of 905 French type 2 diabetic patients, we found evidence of association of INPPL1 SNPs with the presence of hypertension. We conclude that INPPL1 variants may impact susceptibility to disease and/or to subphenotypes involved in the metabolic syndrome in some diabetic patients [less ▲]

Detailed reference viewed: 20 (4 ULiège)
Full Text
See detailTanguy, de la fiction à la réalité
Gavray, Claire ULiege

in Observatoire : Revue d'Action Sociale & Médico-Sociale (2004), 42

Detailed reference viewed: 47 (5 ULiège)
Full Text
Peer Reviewed
See detailA critical analysis of the efficacy of estrogens on spinal and non-spinal fracture reduction
REGINSTER, Jean-Yves ULiege; Richy, Florent; Bruyère, Olivier ULiege

in Reproduction Humaine et Hormones (2004), XVII(5), 419-423

During more than 20 years, estrogens replacement therapy (ERT) has been consistently regarded as the first choice for prevention of trabecular and cortical bone loss in postmenopausal women. However ... [more ▼]

During more than 20 years, estrogens replacement therapy (ERT) has been consistently regarded as the first choice for prevention of trabecular and cortical bone loss in postmenopausal women. However, there are more doubts upon the unequivocal demonstration of the anti-fracture efficacy of ERT, at the spine and hip. Controlled clinical trials and systematic reviews were retrieved, using Medline 1970-2002 and EMBASE 1980-2002. There is a convergent body of evidence that estrogens could significantly reduce the risk of vertebral and non-vertebral fractures, providing this treatment is started early after the menopause and pursued indefinitely. In the recent perspective of the published studies, reevaluating the non-skeletal benefits and harms of ERT in post-menopausal women, other chemical entities might be better options to be used for the specific purpose of preventing or treating post-menopausal osteoporosis. [less ▲]

Detailed reference viewed: 14 (1 ULiège)
Full Text
Peer Reviewed
See detailEpidural levobupivacaine 0.1 % or ropivacaine 0.1 % combined with morphine provides comparable analgesia after abdominal surgery
Senard, Marc ULiege; Kaba, Abdourahmane ULiege; Jacquemin, Murielle et al

in Anesthesia and Analgesia (2004), 98

Detailed reference viewed: 33 (7 ULiège)
Full Text
Peer Reviewed
See detailpolychlorinated biphenyls contamination in women with breast cancer
Charlier, Corinne ULiege; Albert, Adelin ULiege; Zhang, Lixin ULiege et al

in Clinica Chimica Acta (2004), 347

Background: Polychlorinated biphenyls (PCBs) are widespread highly resistant pollutants in the environment with potential adverse health effects on humans. The aim of the study was to compare PCBs ... [more ▼]

Background: Polychlorinated biphenyls (PCBs) are widespread highly resistant pollutants in the environment with potential adverse health effects on humans. The aim of the study was to compare PCBs contamination in women suffering from breast cancer with presumably healthy women. Methods: A gas-chromatography/mass-spectrometry method was used to identify and quantify seven PCBs congeners (IUPAC 28, 52, 101, 118, 138, 153,180) in blood from 60 cases of breast cancer and 60 age-matched healthy controls. Results: Cases and controls had similar risk profiles, except for menopausal status (respectively 82% vs. 65%, p=0.014). PCBs were detectable in 69.1% of the samples. Total blood level of PCBs was significantly different (p=0.012) in cases (7.08±7.51 ppb) and controls (5.10±5.15 ppb). The relationship between PCBs concentrations in serum and risk factor was mainly due to serum levels of PCB153, which were significantly higher in breast cancer women than in disease-free subjects (1.63±1.26 ppb vs. 0.63±0.78 ppb, p<0.0001), even after accounting for other potential risk factors. Conclusions: These results suggest that environmental exposure to PCBs may contribute to multifactorial pathogenesis of breast cancer. [less ▲]

Detailed reference viewed: 44 (15 ULiège)
Full Text
Peer Reviewed
See detailCompte rendu de "La costanza della ragione. Soggetto Oggetto e testualità nella poesia italiana del Novecento"
Benzoni, Pietro ULiege

in Stilistica e Metrica Italiana (2004), IV(4), 243-45

Detailed reference viewed: 16 (3 ULiège)
Full Text
Peer Reviewed
See detailWhen Memory Shifts Toward More Typical Category Exemplars: Accentuation Effects in the Recollection of Ethnically Ambiguous Faces
Corneille, Olivier; Huart, Johanne ULiege; Becquart, Emilie et al

in Journal of Personality & Social Psychology (2004), 86

In 4 studies, the authors examined the impact of categorization on the recollection of ethnically ambiguous faces. Participants were presented with faces lying at various locations on mixed-race continua ... [more ▼]

In 4 studies, the authors examined the impact of categorization on the recollection of ethnically ambiguous faces. Participants were presented with faces lying at various locations on mixed-race continua (i.e., Caucasian–North African and Caucasian–Asian faces were used as source images in a morphing program). In all studies, the prevalence of exclusive ethnic features in a face distorted participants’ recollections of the face toward faces more typical of the category. Specifically, the recollection of 30% North African (or 30% Asian) faces shifted toward Caucasian source faces, whereas the recollection of 70% North African (or 70% Asian) faces shifted toward North African (Asian) source faces. Memory distortions did not emerge for extremely ambiguous (50%) faces and proved larger on mixed-race than same-race continua (Studies 3 and 4). Memory distortions also emerged with high levels of confidence. The authors elaborate on the theoretical and practical implications of these findings. [less ▲]

Detailed reference viewed: 65 (23 ULiège)
Full Text
Peer Reviewed
See detailAd libitum feeding following ovariectomy in female Beagle dogs: effect on maintenance energy requirement and on blood metabolites.
Jeusette, Isabelle; Detilleux, Johann ULiege; Cuvelier, Christine ULiege et al

in Journal of Animal Physiology & Animal Nutrition (2004), 88(3-4), 117-21

The aim of this study was (i) to evaluate the effect of ovariectomy on daily energy requirement in Beagle dogs, and (ii) to evaluate the effects of ad libitum feeding with a high energy diet on energy ... [more ▼]

The aim of this study was (i) to evaluate the effect of ovariectomy on daily energy requirement in Beagle dogs, and (ii) to evaluate the effects of ad libitum feeding with a high energy diet on energy consumption, body weight gain and blood metabolites in these spayed dogs. Four young adult female Beagle dogs were used. Ovariectomy induced a significant decrease of daily energy requirement in dogs. Ad libitum feeding, initiated 6 months after spaying, induced a significant increase in consumption in spayed dogs. This overconsumption was greatest during the first month of ad libitum feeding but continued for the entire 4 months of this period. When fed ad libitum, dogs gained excess body weight without significant effect on plasma cholesterol, triglycerides, glucose and insulin, at short term. These data suggest that energy intake should be strictly controlled to avoid excess weight gain in spayed dogs. [less ▲]

Detailed reference viewed: 71 (1 ULiège)
Full Text
Peer Reviewed
See detailNew interaction formulae for beam-columns in Eurocode 3: The French-Belgian approach
Boissonnade, N.; Jaspart, Jean-Pierre ULiege; Muzeau, J. P. et al

in Journal of Constructional Steel Research (2004), 60(3-5, MAR-MAY), 421-431

This paper presents one of the two new proposals for beam-column interaction formulae, which will be made available in the forthcoming EN version of Eurocode 3. It is based on second-order in-plane ... [more ▼]

This paper presents one of the two new proposals for beam-column interaction formulae, which will be made available in the forthcoming EN version of Eurocode 3. It is based on second-order in-plane elasticity, and has been derived in order to exhibit an understandable physical background, as well as accuracy and consistency with the other resistance and stability formulae of the code. The formulae ensure all the required continuities: between the cross-section classes, from plasticity to elasticity when slenderness and axial force are increasing, and continuity between all the individual stability member checks and cross-section verifications. The paper shows how the basic format may be extended to cover a wider range of cases, i.e. spatial elastic-plastic behaviour with possible lateral-torsional buckling. Through an extensive comparison with the results of FEM numerical simulations of about 15 000 beam-columns, the proposal is found to be safe and accurate. (C) 2003 Elsevier Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 36 (2 ULiège)
Full Text
Peer Reviewed
See detailExploitation of electronic medical records data in primary health care. Resistances and solutions. Study in eight Walloon health care centres.
Vanmeerbeek, Marc ULiege

in Studies in Health Technology & Informatics (2004), 110

INTRODUCTION: The Electronic Medical Records (EMR), used every day for primary health care may constitute an instrument for gathering locally usable data to improve the quality of care and, on a larger ... [more ▼]

INTRODUCTION: The Electronic Medical Records (EMR), used every day for primary health care may constitute an instrument for gathering locally usable data to improve the quality of care and, on a larger scale, be a basis of epidemiological data. In spite of a policy of promotion of the EMR made by the Federation of French-speaking Belgian "Medical Houses", its use remains very marginal. METHODS: Eight Medical Houses, motivated by computerization of medical records have been met. Quantitative indicators of use of the EMR have been assessed. A qualitative assessment of the resistances to computerization, and solutions which can be brought, has been realized through the technique of the nominal group. RESULTS: The use of the EMR remains slight, allowing for exceptions. The proposed solutions could be put together in 5 categories : ethics, training, search for sense, practice and interdisciplinarity. DISCUSSION: The practitioners are willing to computerize if they get immediate advantages (knowledge of their patients and their team operating). They expressed the need of having a tool easy to use, that doesn't make them lose time and that has respect for their specificity of work and organization (interdisciplinary and self-managed teams). They expressed the need of an external support, under the form of adapted training and supervision for the data management. Ethical concerns (security, data transfer, place of the computer in the relationship with the patient) are surprisingly not present enough. [less ▲]

Detailed reference viewed: 51 (12 ULiège)
Full Text
Peer Reviewed
See detailDeux protocoles d’hyperimmunisation au moyen de vaccins marqués réduisent l’incidence de séroconversion envers l’herpèsvirus bovin 1 en cheptels laitiers : résultats d’une étude sur le terrain
Dispas, M.; Lemaire, Mylène; Speybroeck, N. et al

in Annales de Médecine Vétérinaire (2004), 148(1), 47-61

A 28 months long cohort study was organized in dairy herds in Belgium, to assess the efficacy of hyperimmunisation as a tool for the control of infectious bovine rhinotracheitis. Two protocols of ... [more ▼]

A 28 months long cohort study was organized in dairy herds in Belgium, to assess the efficacy of hyperimmunisation as a tool for the control of infectious bovine rhinotracheitis. Two protocols of hyperimmunisation in which glycoprotein-E deleted marker vaccines were repeatedly administered were compared to a positive control group in which the usual vaccination protocols were authorised. The two hyperimmunisation protocols differed in the primovaccination : the first group was treated with an attenuated vaccine firstly given intra-nasally then by intramuscular route whereas the second group was given an inactivated vaccine by subcutaneous injection. Afterwards, booster vaccinations were the same in both groups : an inactivated vaccine was administered by subcutaneous route every 6 months. In the control group, as a rule, part of the herd was vaccinated annually. For each group, 6 half-yearly reports specify : 1. the evolution of the population, categorized by birth half-year, 2. the incidence of seroconversion against gE in the cohorts and 3. the evolution of the gE seroprevalence. The survival curves of the hyperimmunised groups show a significantly higher proportion (P < 0,001) of animals remaining seronegative against glycoprotein- E compared to the positive control group. No significant difference was shown between the two protocols of hyperimmunisation. Both of them could then be used as tools for the control of infectious bovine rhinotracheitis. [less ▲]

Detailed reference viewed: 65 (1 ULiège)
Full Text
See detailMultivariate animal model estimates of genetic, environmental and phenotypic correlations for early lactation milk yield and composition in Tunisian Holstein-Friesians
Othmane, Mohamed Houcine; Ben Hamouda, Mohamed; Hammami, Hedi ULiege

in Interbull Bulletin (2004), 32

Detailed reference viewed: 58 (1 ULiège)
Full Text
Peer Reviewed
See detailModelling The Dynamic Distribution Of Spray Deposits
Lebeau, Frédéric ULiege

in Biosystems Engineering (2004), 89(3),

A mathematical model to estimate the spray distribution of phytopharmaceutical deposits under a spray boom is proposed. It focuses on the need to take account of the dynamic effects of the forward ... [more ▼]

A mathematical model to estimate the spray distribution of phytopharmaceutical deposits under a spray boom is proposed. It focuses on the need to take account of the dynamic effects of the forward movement of the boom. These are related both to the horizontal and vertical boom movement and to the influence of aerodynamic factors on the nozzle spray distribution. The distribution of the spray deposits is computed by multiplying the nozzle spray pattern by the time needed to move from one position to the next. Mathematically, this is expressed by a convolution of the trajectory function with the nozzle spray pattern function. The model is validated through a dynamic test bench to reproduce the boom movements observed in the field. The chosen method to measure the distribution of the spray deposits is a chemical dosage of the sprayed potassium chloride (KCl) solution collected in Petri dishes. A pulse-width modulation (PWM) nozzle body fitted on the test bench is used to generate a dynamic distribution of spray deposits from which the dynamic two-dimensional nozzle spray pattern is reconstructed. This dynamic nozzle spray pattern introduced in the model allows a far better estimation of the spray deposit distribution to be made than the one obtained using the static nozzle spray pattern which was computed using filtered back-projection. [less ▲]

Detailed reference viewed: 50 (7 ULiège)
Full Text
Peer Reviewed
See detailNMR assignments of the major Cannabinoids and cannabiflavonoids isolated from flowers of Cannabis sativa
Choi, Y. H.; Hazekamp, A.; Peltenburg-Looman, A. M. G. et al

in Phytochemical Analysis (2004), 15(6, NOV-DEC), 345-354

The complete H-1- and C-13-NMR assignments of the major Cannabis constituents, Delta(9)-tetrahydrocannabinol, tetrahydrocannabinolic acid, A-tetrahydrocannabinol, cannabigerol, cannabinol, cannabidiol ... [more ▼]

The complete H-1- and C-13-NMR assignments of the major Cannabis constituents, Delta(9)-tetrahydrocannabinol, tetrahydrocannabinolic acid, A-tetrahydrocannabinol, cannabigerol, cannabinol, cannabidiol, cannabidiolic acid, cannflavin A and cannflavin B have been determined on the basis of one- and two-dimensional NMR spectra including H-1- and (13)-NMR, H-1-H-1-COSY, HMQC and HMBC. The substitution of carboxylic acid on the cannabinoid nucleus (as in tetrahydrocannabinolic acid and cannabidiolic acid) has a large effect on the chemical shift of H-1" of the C5 side chain and 2'-OH. It was also observed that carboxylic acid substitution reduces intermolecular hydrogen bonding resulting in a sharpening of the H-5' signal in cannabinolic acid in deuterated chloroform. The additional aromaticity of cannabinol causes the two angular methyl groups (H-8 and H-9) to show identical H-1-NMR shifts, which indicates that the two aromatic rings are in one plane in contrast to the other cannabinoids. For the cannabiflavonoids, the unambiguous assignments of C-3' and C-4' of cannflavin A and B were determined by HMBC spectra. Copyright (C) 2004 John Wiley Sons, Ltd. [less ▲]

Detailed reference viewed: 50 (3 ULiège)
Full Text
Peer Reviewed
See detailA Real-Time Grading Method Of Apples Based On Features Extracted From Defects
Leemans, Vincent ULiege; Destain, Marie-France ULiege

in Journal of Food Engineering (2004), 61(1),

This paper presents a hierarchical grading method applied to Jonagold apples. Several images covering the whole surface of the fruits were acquired thanks to a prototype grading machine. These images were ... [more ▼]

This paper presents a hierarchical grading method applied to Jonagold apples. Several images covering the whole surface of the fruits were acquired thanks to a prototype grading machine. These images were then segmented and the features of the defects were extracted. During a learning procedure, the objects were classified into clusters by k-mean clustering. The classification probabilities of the objects were summarised and on this basis the fruits were graded using quadratic discriminant analysis. The fruits were correctly graded with a rate of 73 %. The errors were found having origins in the segmentation of the defects or for a particular wound, in a confusion with the calyx end. [less ▲]

Detailed reference viewed: 109 (5 ULiège)
Full Text
Peer Reviewed
See detailA Parasite Reveals Cryptic Phylogeographic History of Its Host: The Colonization of the Western Mediterranean Islands
Nieberding, Caroline; Morand, Serge; Libois, R. et al

in Multidisciplinarity for Parasites, Vectors and Parasitic Diseases (2004), 1

Detailed reference viewed: 9 (0 ULiège)
Full Text
Peer Reviewed
See detailModelisation de la reponse des flux de respiration d'un sol forestier selon les principales variables climatiques.
Perrin, Dominique ULiege; Laitat, E.; Aubinet, Marc ULiege et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2004), 8(1),

Detailed reference viewed: 32 (1 ULiège)
Full Text
Peer Reviewed
See detailRecent data on a current zoonosis: alveolar echinococcosis due to Echinococcus multilocularis
Hanosset, Régis; Mignon, Bernard ULiege; Losson, Bertrand ULiege

in Annales de Médecine Vétérinaire (2004), 148(4), 153-167

E. multilocularis is a small tapeworm which uses different species of foxes and rodents as final and intermediate hosts respectively. In humans, infection with the metacestode stage can result in a ... [more ▼]

E. multilocularis is a small tapeworm which uses different species of foxes and rodents as final and intermediate hosts respectively. In humans, infection with the metacestode stage can result in a potentially lethal liver condition named alveolar echinococcosis (AE). Recent studies in central Europe have show that E. multilocularis has a wider geographic range than previously anticipated. By the end of the 1980s, endemic areas of E. multilocularis were know to exist in only four countries, but now the parasite is present in at least 14 European countries. This paper provide recent data on the biology of E. multilocularis, the epidemiology of AE and the different tools which are available to treat or prevent this disease which seems in apparent extension. [less ▲]

Detailed reference viewed: 83 (7 ULiège)
Full Text
Peer Reviewed
See detailModelling of electromagnetic waves in periodic media with finite elements
Nicolet, A.; Guenneau, S.; Geuzaine, Christophe ULiege et al

in Journal of Computational & Applied Mathematics (2004), 168

Detailed reference viewed: 187 (11 ULiège)
Full Text
Peer Reviewed
See detailSkin compatibility of cyclodextrins and their derivatives: a comparative assessment using a corneoxenometry bioassay.
Piel, Géraldine ULiege; Moutard, S.; Uhoda, Emmanuelle ULiege et al

in European Journal of Pharmaceutics & Biopharmaceutics (2004), 57(3), 479-82

Few studies have been performed to assess the risk of skin damage by cyclodextrins (CD) and they have yielded contradictory results. The present study was conducted using the corneoxenometry bioassay on ... [more ▼]

Few studies have been performed to assess the risk of skin damage by cyclodextrins (CD) and they have yielded contradictory results. The present study was conducted using the corneoxenometry bioassay on human stratum corneum to compare the skin compatibility of CD currently used in pharmaceutical preparations (betaCD, gammaCD, Rameb, Dimeb, Trimeb, HP-betaCD and HP-gammaCD) and that of new amphiphilic CD derivatives, namely, the phospholipidyl-CD (DMPE-Dimeb and DMPE-Trimeb). All the tested CD were well tolerated by the stratum corneum at a concentration of 5%. However, inter-individual reactivity was larger for DMPE-Dimeb, suggesting a more aggressive trend for this compound. Cutaneous Index of Mildness values obtained confirm that Dimeb is able to extract some skin components and shows that DMPE-Dimeb performs similarly. [less ▲]

Detailed reference viewed: 43 (10 ULiège)
Full Text
Peer Reviewed
See detailFeeding performance in heterochronic alpine newts is consistent with trophic niche and maintenance of polymorphism
Denoël, Mathieu ULiege

in Ethology (2004), 110(2), 127-136

The feeding performances of two heterochronic morphs of the Alpine newt Triturus alpestris were investigated in laboratory experiments. Although both morphs are able to feed in the aquatic habitat, the ... [more ▼]

The feeding performances of two heterochronic morphs of the Alpine newt Triturus alpestris were investigated in laboratory experiments. Although both morphs are able to feed in the aquatic habitat, the hydrodynamics of prey capture differ between morphs. In paedomorphs water sucked with prey is expelled behind the mouth through gill bars. In metamorphs, water is expelled by the mouth as gill slits are closed. Feeding performance was better in paedomorphs than in metamorphs when foraging on aquatic crustaceans, but paedomorphs were less successful when foraging on terrestrial invertebrates caught at the water surface. These differences in prey capture success related to prey type allow the two morphs to use specific resources in their aquatic habitat. These results are consistent with previous studies that showed diet differentiation between morphs in natural populations. Such resource partitioning is a factor favouring the maintenance of facultative paedomorphosis in natural populations. [less ▲]

Detailed reference viewed: 110 (12 ULiège)
Full Text
Peer Reviewed
See detailAromatic Side-Chain Interactions In Proteins: Near- And Far-Sequence Tyr-X Pairs
Meurisse, R.; Brasseur, Robert ULiege; Thomas, Annick ULiege

in Proteins-Structure Function and Genetics (2004), 54(3), 478-90

In the present study, an extensive analysis of the aromatic Tyr-X interactions is performed on a data set of 593 PDB structures, X being Phe, His, Tyr, and Trp. The nonredundant Tyr-X pairs (2645) were ... [more ▼]

In the present study, an extensive analysis of the aromatic Tyr-X interactions is performed on a data set of 593 PDB structures, X being Phe, His, Tyr, and Trp. The nonredundant Tyr-X pairs (2645) were retained and separated by both the residue distance in the sequence and the secondary structures they bridge. Similar to the Phe-X and His-X pairs, the far-sequence Tyr-X pairs (X partner > five apart in the sequence: 74%) show comparable secondary structures and conformers for either type of X partner, in contrast with the near-sequence Tyr-X pairs (26%). As the Phe-X pairs, the near-sequence Tyr-X pairs stabilize secondary structures, mainly the alpha- helices (positions 1, 3, and 4) and the beta-strands (position 2). Like the Phe-X and His-X pairs, most far-sequence Tyr-X pairs (34%) bridge beta-strands and only 11% bridge helices. As for the Phe-X and the His-X pairs, the X partners of the far-sequence Tyr-X pairs are frequently "above" the tyrosine ring with tilted and normal rings, whereas the X partner of the near-sequence Tyr-X pairs gradually moves from the "aside" to the "above" location, together with a progressive decrease of normal and increase of parallel rings, respectively. Unlike the His-X pairs, the interactions of the hetroatom in Tyr-X pairs are only favored with a sequence position +4 and over, owing to the spatial accessibility of the heteroatom. [less ▲]

Detailed reference viewed: 4 (0 ULiège)
Full Text
Peer Reviewed
See detailMotor cortex excitability in Alzheimer's disease and in subcortical ischemic vascular dementia.
Alagona, Giovanna; Ferri, Raffaele; Pennisi, Giovanni et al

in Neuroscience Letters (2004), 362(2), 95-8

Twenty Alzheimer's disease (AD) patients, 20 subcortical ischemic vascular dementia (SIVD) patients and 20 neurologically and cognitively normal subjects underwent transcranial magnetic stimulation to ... [more ▼]

Twenty Alzheimer's disease (AD) patients, 20 subcortical ischemic vascular dementia (SIVD) patients and 20 neurologically and cognitively normal subjects underwent transcranial magnetic stimulation to study motor cortex excitability changes. Motor threshold (MT), amplitude of motor evoked potentials, silent period and the H/M ratio (amplitude of maximal Hoffman reflex vs. that of maximal motor response) were considered. MT was lower in SIVD patients when compared with AD patients (P = 0.003) and the control group (P < 0.001) and lower in AD patients when compared with the control group (P < 0.001). The increment of motor cortex excitability in AD and SIVD did not lead us to distinguish clearly the two types of dementia. It is likely that the electrophysiological similarity between AD and SIVD could represent another common mechanism shared from these forms of dementia. [less ▲]

Detailed reference viewed: 25 (0 ULiège)
Full Text
Peer Reviewed
See detail“Peculiar Sites of Amnesia: Recovering the ‘Eclipsed Figures of the Past’ in Francis Quamina Farrier’s The Slave and the Scroll and Michael Gilkes’s Couvade.”
Bada, Valérie ULiege

in Bridges Across Chasms. Towards a Transcultural Future in Caribbean Literature. Ed. Bénédicte Ledent. (2004)

Detailed reference viewed: 18 (2 ULiège)
Full Text
Peer Reviewed
See detailSpawning movements of European grayling Thymallus thymallus in the River Aisne (Belgium)
Ovidio, Michaël ULiege; Parkinson, Denis; Sonny, Damien et al

in Folia Zoologica (2004), 53(1), 87-98

In three consecutive years (1998 to 2000), 20 adult grayling Thymallus thymallus (L.) (FL +/- SD: 326 +/- 43 mm) were radio-tracked during circum reproduction period (February to May) in the River Aisne ... [more ▼]

In three consecutive years (1998 to 2000), 20 adult grayling Thymallus thymallus (L.) (FL +/- SD: 326 +/- 43 mm) were radio-tracked during circum reproduction period (February to May) in the River Aisne, Belgium. Before the spawning period, grayling remained consistently in the pool-riffle sequence in which they had been captured. Pre-spawning migration time extended from 7 to 29 March. Distances travelled during the spawning migration ranged from 70 to 4980 in (mean +/- S.E.: 1234 +/- 328 m). Spawning migrations stalled under conditions of decreasing water level and increasing water temperature in a thermal range (daily mean Tdegrees) from 5 to 8 degreesC. Spawners remained from 1 to 31 days (mean +/- S.D.: 10.4 +/- 9.8 days) at the spawning grounds and performed a post-spawning homing from 28 March to 18 April in decreasing water flow and in a thermal range (daily mean Tdegrees) from 7 to 11 degreesC. This study demonstrates that migration patterns of grayling are similar between years, but with a timing adjusted as a response to annual variations of the hydroclimatic conditions. [less ▲]

Detailed reference viewed: 251 (14 ULiège)
Full Text
Peer Reviewed
See detailFractures vertébrales ostéoporotiques et raloxifène (Evista°).
Reginster, Jean-Yves ULiege

in Patient Care (2004), 27

Detailed reference viewed: 10 (1 ULiège)
Full Text
Peer Reviewed
See detailPotential neuroprotective properties of atracurium and cisatracurium in neurosurgical anaesthesia
Hans, Pol ULiege; Bonhomme, Vincent ULiege

in European Journal of Anaesthesiology (2004), 21(4), 334-335

Detailed reference viewed: 15 (0 ULiège)
Full Text
Peer Reviewed
See detailSite Index Curves For Alnus Glutinosa (L.) Gaertn. In Southern Belgium: Effect Of Site On Curve Shape
Thibaut, André; Claessens, Hugues ULiege; Rondeux, Jacques ULiege

in Forestry (2004), 77(2), 157-171

Site index curves were developed for Alnus glutinosa (L.) Gaertn. in southern Belgium. Five models of Duplat and Tran-Ha were fitted to a data set of 15 stem analyses divided into two data subsets clearly ... [more ▼]

Site index curves were developed for Alnus glutinosa (L.) Gaertn. in southern Belgium. Five models of Duplat and Tran-Ha were fitted to a data set of 15 stem analyses divided into two data subsets clearly characterized by different height growth patterns. Model III was found to fit data sets best, both separately and combined. Various statistical comparisons made between the two curve sets underline shape variations corresponding to different soil conditions. A comparison between Belgian and other European curves highlights the effect of the soil on growth curve shape, which is at least as important as that of climatic factors. However, for practical reasons, the use of a general global model, which does not specifically take into account differences in height growth patterns, is satisfactory for productivity evaluation and is recommended for forest management. [less ▲]

Detailed reference viewed: 58 (9 ULiège)
Full Text
Peer Reviewed
See detailPathbase: A new reference resource and database for laboratory mouse pathology
Schofield, P. N.; Bard, J. B. L.; Boniver, Jacques ULiege et al

in Radiation Protection Dosimetry (2004), 112(4 Sp. Iss. SI), 525-528

Pathbase (http://www.pathbase.net) is a web accessible database of histopathological images of laboratory mice, developed as a resource for the coding and archiving of data derived from the analysis of ... [more ▼]

Pathbase (http://www.pathbase.net) is a web accessible database of histopathological images of laboratory mice, developed as a resource for the coding and archiving of data derived from the analysis of mutant or genetically engineered mice and their background strains. The metadata for the images, which allows retrieval and interoperability with other databases, is derived from a series of orthogonal ontologies and controlled vocabularies. One of these controlled vocabularies, MPATH, was developed by the Pathbase Consortium as a formal description of the content of mouse histopathological images. The database currently has over 1000 images on-line with 2000 more under curation and presents a paradigm for the development of future databases dedicated to aspects of experimental biology. [less ▲]

Detailed reference viewed: 12 (0 ULiège)
Full Text
Peer Reviewed
See detailA nation-wide project for the revision of the Belgian nursing minimum dataset: from concept to implementation.
SERMEUS, Walter; VAN DEN HEEDE, Koen; MICHIELS, Dominik et al

in Studies in Health Technology & Informatics (2004), 110

Detailed reference viewed: 19 (4 ULiège)
Full Text
Peer Reviewed
See detailAggregate Matching Efficiency: A Stochastic Production Frontier Approach, France 1990–1994
Ibourk, Aomar; Maillard, Bénédicte; Perelman, Sergio ULiege et al

in Empirica (2004), 31

We evaluate the determinants of aggregate matching efficiency changes through a stochastic translog production frontier model. The efficiency coefficient is represented by a stochastic function of ... [more ▼]

We evaluate the determinants of aggregate matching efficiency changes through a stochastic translog production frontier model. The efficiency coefficient is represented by a stochastic function of variables meant to capture workers and firms characteristics. The model is estimated on French data covering twenty-two regions from March 1990 till February 1995. Our estimates suggest that aggregate matching efficiency has decreased steadily in the early nineties. There are also wide cross-regional differences. On average, about 30% of the variations of efficiency observed across time and regions can be related to changes in the explanatory variables used in the model. The most important explanatory variables are the proportion of youngsters, females and immigrants in the stock of job seekers. Long-term unemployment has a significant negative effect, population density a significant positive one. The huge decline in the proportion of permanent job offers has apparently little effect on matching efficiency. [less ▲]

Detailed reference viewed: 31 (2 ULiège)
Full Text
Peer Reviewed
See detailCriminografie en methodologie
Lemaître, André ULiege; Goethals, Johan; Parmentier, Stephan et al

in Panopticon : Tijdschrift voor Strafrecht, Criminologie en Forensisch Welzijnswerk (2004)

Detailed reference viewed: 29 (0 ULiège)
Full Text
Peer Reviewed
See detailDéveloppement morphosyntaxique des enfants ayant des troubles de développement du langage : des données francophones.
Parisse, Christophe; Maillart, Christelle ULiege

in Enfance : Psychologie, Pédagogie, Neuropsychiatrie, Sociologie (2004), 56

Children’s morphosyntactic disorders have been studied extensively over the past few years, but mostly in English-speaking children. Recent data on French-speaking children are presented in the current ... [more ▼]

Children’s morphosyntactic disorders have been studied extensively over the past few years, but mostly in English-speaking children. Recent data on French-speaking children are presented in the current article. There are three key-periods in morphological development : (1) language emergence ; (2) beginning of morphosyntax ; (3) later development. Different morphosyntactic features correspond to each of these periods in the language production of SLI children. The difference between language delay and language disorder is difficult to tease apart in young children. However, as children grow older, it becomes possible to identify characteristics that are specific to children with language disorders and others that are specific to French-speaking SLI children. [less ▲]

Detailed reference viewed: 706 (38 ULiège)
Full Text
Peer Reviewed
See detailA europium-151 Mossbauer spectral study of Eu14MnP11, EuMnAs11, and Eu14MnSb11
Hermann, Raphaël ULiege; Grandjean, Fernande ULiege; Kauzlarich, S. M. et al

in Inorganic Chemistry (2004), 43(22), 7005-7013

The europium-151 Mossbauer spectra of the EU14MnP11, Eu14MnAs11, and Eu14MnSb11 Zintl compounds, measured between 4.2 and 100 K, reveal europium(11) for all four crystallographically inequivalent europium ... [more ▼]

The europium-151 Mossbauer spectra of the EU14MnP11, Eu14MnAs11, and Eu14MnSb11 Zintl compounds, measured between 4.2 and 100 K, reveal europium(11) for all four crystallographically inequivalent europium sites in EU14MnAs11 and Eu14MnSb11 and europium(11) and europium(III) for the three 32g and the 16f europium sites in Eu14MnP11, respectively. Below the ordering temperatures of 52, 74, and 92 K, only very small hyperfine fields of 2-4 T are observed at the europium sites as a result of the polarization by the manganese magnetic moments. At 4.2 K, the europium(11) magnetic moments are ordered, and hyperfine fields of 24.4, 24.8, and 19.3 T are observed in Eu14MnP11, Eu14MnAs11, and Eu14MnSb11, respectively, fields that are typical for magnetically ordered europium(11) ions. At 4.2 K the 16f europium(III) sites in EU14MnP11 experience a transferred hyperfine field of 33 T from the neighboring ordered europium(11) moments. Between its Curie temperature and 4.2 K, the europium-151 Mossbauer spectra of Eu14MnSb11 reveal that the europium(11) moments order below ca. 13 K, i.e., below the second magnetic transition observed in magnetic measurements. Between their Curie temperatures and 4.2 K, the europium-151 Mossbauer spectra of EU14MnP11 and EU14MnAs11 are complex and have been analyzed with two models, models that give equivalently good fits. However, the second model in which the spectra are fit with a three-dimensional relaxation of the europium(II) and europium(Ill) hyperfine fields is preferred for its physical meaning and its reduced number of fitted parameters. [less ▲]

Detailed reference viewed: 20 (0 ULiège)
Full Text
See detailLe décasyllabe de Marie Étienne et son écriture générale (Anatolie, 1997)
Purnelle, Gérald ULiege

in Formes Poétiques Contemporaines (2004), 2

Detailed reference viewed: 22 (6 ULiège)
Full Text
Peer Reviewed
See detailPlurilinguisme hybride et méthodes d’apprentissage de la lecture
Lucchini, Silvia ULiege

in Dialogues et Cultures (2004), 49

Detailed reference viewed: 34 (4 ULiège)
Full Text
See detailPoesia e cenário : o interior, o excesso, o nada – a propósito do “Lamento das puberdades difíceis”
Durand, Pascal ULiege

in Inimigo Rumor, Revista de poesia (2004), 16(1er semestre),

Detailed reference viewed: 27 (9 ULiège)
Full Text
Peer Reviewed
See detailSuspension de l’exigibilité de créances de l’Etat : l’incidence d’un fédéralisme centrifuge sur le principe d’égalité
Rosoux, Géraldine ULiege

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2004)

The article analyzes a mechanism of compensation of State debts, and examines the question of the protection of fundamental rights such as equality in the Belgian federal State.

Detailed reference viewed: 94 (15 ULiège)
Full Text
Peer Reviewed
See detailGenomic structure, organisation, and promoter analysis of the bovine (Bos taurus) Mx1 gene
Gérardin; Baise, Etienne ULiege; Pire, Grégory et al

in Gene (2004), 326

Some MX proteins are known to confer a specific resistance against a panel of single-stranded RNA viruses. Many diseases due to such viruses are known to affect cattle worldwide, raising the possibility ... [more ▼]

Some MX proteins are known to confer a specific resistance against a panel of single-stranded RNA viruses. Many diseases due to such viruses are known to affect cattle worldwide, raising the possibility that the identification of an antiviral isoform of a bovine MX protein would allow the implementation of genetic selection programs aimed at improving innate resistance of cattle. With this potential application in mind, the present study was designed to isolate the bovine Mx1 gene including its promoter region and to investigate its genomic organisation and promoter reactivity. The bovine Mx1 gene is made up of 15 exons. All exon-intron boundaries conformed to the consensus sequences. A PCR product that contained a approximately 1-kb, 5'-flanking region upstream from the putative transcription start site was sequenced. Unexpectedly, this DNA region did not contain TATA or CCAAT motifs. A computer scan of the region disclosed a series of putative binding sites for known cytokines and transcription factors. There was a GAAAN(1-2)GAAA(C/G) motif, typical of an interferon-sensitive responsive element, between -118 and -107 from the putative transcription start site. There were also a NF-kappaB, two interleukin-6 binding sites, two Sp1 sites and five GC-rich boxes. The region also contained 12 stretches of the GAAA type, as described in all IFN-inducible genes. Bovine Mx1 expression was assessed by Northern blotting and immunofluorescence in the Madin Darby bovine kidney cells (MDBK) cell line treated with several stimuli. In conclusion, the bovine Mx1 gene and promoter region share the major structural and functional characteristics displayed by their homologs described in the rainbow trout, chicken, mouse and man. [less ▲]

Detailed reference viewed: 28 (1 ULiège)
Full Text
Peer Reviewed
See detailImmunohistochemical aid at risk stratification of melanocytic neoplasms.
Quatresooz, Pascale ULiege; Arrese Estrada, Jorge ULiege; Pierard, Claudine ULiege et al

in International Journal of Oncology (2004), 24(1), 211-6

There is increasing awareness of the population about the risk of cutaneous melanoma. In recent years, some improvement was gained in the early recognition of clinical warning signs using dermoscopy. As a ... [more ▼]

There is increasing awareness of the population about the risk of cutaneous melanoma. In recent years, some improvement was gained in the early recognition of clinical warning signs using dermoscopy. As a result, the number of puzzling cases exhibiting limited classical clues for malignancy are submitted to the dermatopathologist. Thus, the risk of microscopic uncertainty or misdiagnosis may be increasing. The aim of the study was to assess retrospectively the contribution of immunohistochemistry in establishing the histological diagnosis of 520 melanocytic neoplasms. According to the disease evolution and the histological presentation, 6 profiles of phenotypical expressions were distinguished. [less ▲]

Detailed reference viewed: 19 (8 ULiège)
Full Text
See detailSubdivision of the Famennian Stage into four substages and correlation with the neritic and continental Miospore Zonation
Streel, Maurice ULiege

in Newsletter. Subcommission on Devonian Stratigraphy (2004), 21

Detailed reference viewed: 29 (3 ULiège)
Full Text
Peer Reviewed
See detailGenetic structuralism, psychological sociology and pragmatic social actor theory, Proposals for a convergence of French sociologies
Frère, Bruno ULiege

in Theory, Culture & Society (2004), 21(3), 85-99

This paper would like to show that Wittgenstein and Freud have exerted a considerable - though narrow - influence on Bourdieu's sociology. But they also pervade the theoretical development of two other ... [more ▼]

This paper would like to show that Wittgenstein and Freud have exerted a considerable - though narrow - influence on Bourdieu's sociology. But they also pervade the theoretical development of two other currents, which have emerged in French Sociology in the last few years, and were developed by L. Boltanski and L. Thevenot, on the one hand, and B. Lahire, on the other. Although they do not make it explicit, the advocates of these two currents have nevertheless been influenced by Wittgenstein and Freud. Thus Boltanski has drawn on Wittgenstein to develop a sociology which gives primacy to the social actor's interpretation of his or her situation through lay theorising. Lahire's work clearly pays a debt to Freud with his psychological sociology. It would therefore be interesting, in the first instance, to tease out how Wittgenstein and Freud, respectively, have influenced these two systems to demonstrate that they can indeed be used to generate new sociological currents, other than Bourdieu's own. This would then allow us to explore how they could be used to fill any gaps in Bourdieu's work, thus giving the latter renewed relevance and staunching its stagnating tendencies. But, ultimately, this analysis aims to show how Wittgenstein’s and Freud's theoretical influences can lead the way towards a theoretical synthesis between Bourdieu's critical sociology, Boltanski's social actor theory and Lahire's psychological sociology. Currently, these three currents operate independently of each other, without any kind of dialogue. And yet, far from being incompatible, these sociologies offer opportunities for exploring how they might complement each other and for mutual enrichment. [less ▲]

Detailed reference viewed: 129 (5 ULiège)
Full Text
Peer Reviewed
See detail15-deoxy-delta12,14-prostaglandin J2 inhibits Bay 11-7085-induced sustained extracellular signal-regulated kinase phosphorylation and apoptosis in human articular chondrocytes and synovial fibroblasts
Relic, Biserka ULiege; Benoit, Valerie; Franchimont, Nathalie et al

in Journal of Biological Chemistry (2004), 279(21), 399-403

We have previously shown that nuclear factor-kappaB inhibition by adenovirus expressing mutated IkappaB-alpha or by proteasome inhibitor increases human articular chondrocytes sensibility to apoptosis ... [more ▼]

We have previously shown that nuclear factor-kappaB inhibition by adenovirus expressing mutated IkappaB-alpha or by proteasome inhibitor increases human articular chondrocytes sensibility to apoptosis. Moreover, the nuclear factor-kappaB inhibitor BAY11-7085, a potent anti-inflammatory drug in rat adjuvant arthritis, is itself a proapoptotic agent for chondrocytes. In this work, we show that BAY 11-7085 but not the proteasome inhibitor MG-132 induced a rapid and sustained phosphorylation of extracellular signal-regulated kinases (ERK1/2) in human articular chondrocytes. The level of ERK1/2 phosphorylation correlated with BAY 11-7085 concentration and chondrocyte apoptosis. 15-Deoxy-delta(12,14)-prostaglandin J2 (15d-PGJ2) and its precursor prostaglandin (PG) D2 but not PGE2 and PGF2alpha rescued chondrocytes from BAY 11-7085-induced apoptosis. 15d-PGJ2 markedly inhibited BAY 11-7085-induced phosphorylation of ERK1/2. BAY 11-7085 also induced ERK1/2 phosphorylation and apoptosis in human synovial fibroblasts, and these reactions were down-regulated by 15d-PGJ2. Further analysis in synovial fibroblasts showed that only molecules that suppressed BAY 11-7085-induced phosphorylation of ERK1/2 (i.e. 15d-PGJ2, PGD2, and to a lesser extent, MEK1/2 inhibitor UO126, but not prostaglandins E2 and F2alpha or peroxisome proliferator-activated receptor-gamma agonist ciglitazone) were able protect cells from apoptosis. These results suggested that the antiapoptotic effect of 15d-PGJ2 on chondrocytes and synovial fibroblasts might involve inhibition of ERK1/2 phosphorylation. [less ▲]

Detailed reference viewed: 29 (4 ULiège)
Full Text
See detailTrajectoires professionnelles féminines : flexibilités et enjeux de genre
Gavray, Claire ULiege

in Bulletin Sophia (2004), 37

Detailed reference viewed: 44 (13 ULiège)
Full Text
Peer Reviewed
See detailControl of vesicle fusion by a tyrosine phosphatase.
Huynh, Huong; Bottini, Nunzio; Williams, Scott et al

in Nature cell biology (2004), 6(9), 831-9

The tyrosine phosphatase PTP-MEG2 is targeted by its amino-terminal Sec14p homology domain to the membrane of secretory vesicles. There it regulates vesicle size by promoting homotypic vesicle fusion by a ... [more ▼]

The tyrosine phosphatase PTP-MEG2 is targeted by its amino-terminal Sec14p homology domain to the membrane of secretory vesicles. There it regulates vesicle size by promoting homotypic vesicle fusion by a mechanism that requires its catalytic activity. Here, we identify N-ethylmaleimide-sensitive factor (NSF), a key regulator of vesicle fusion, as a substrate for PTP-MEG2. PTP-MEG2 reduced the phosphotyrosine content of NSF and co-localized with NSF and syntaxin 6 in intact cells. Furthermore, endogenous PTP-MEG2 co-immunoprecipitated with endogenous NSF. Phosphorylation of NSF at Tyr 83, as well as an acidic substitution at the same site, increased its ATPase activity and prevented alphaSNAP binding. Conversely, expression of a Y83F mutant of NSF caused spontaneous fusion events. Our results suggest that the molecular mechanism by which PTP-MEG2 promotes secretory vesicle fusion involves the local release of NSF from a tyrosine-phosphorylated, inactive state. This represents a novel mechanism for localized regulation of NSF and the first demonstrated role for a protein tyrosine phosphatase in the regulated secretory pathway. [less ▲]

Detailed reference viewed: 71 (0 ULiège)
Peer Reviewed
See detailMixture model for inferring susceptibility to mastitis in dairy cattle: a procedure for likelihood-based inference
Gianola, D.; Odegard, J.; Heringstad, B. et al

in Genetics, Selection, Evolution (2004), 36(1, JAN-FEB), 3-27

A Gaussian mixture model with a finite number of components and correlated random effects is described. The ultimate objective is to model somatic cell count information in dairy cattle and to develop ... [more ▼]

A Gaussian mixture model with a finite number of components and correlated random effects is described. The ultimate objective is to model somatic cell count information in dairy cattle and to develop criteria for genetic selection against mastitis, an important udder disease. Parameter estimation is by maximum likelihood or by an extension of restricted maximum likelihood. A Monte Carlo expectation- maximization algorithm is used for this purpose. The expectation step is carried out using Gibbs sampling, whereas the maximization step is deterministic. Ranking rules based on the conditional probability of membership in a putative group of uninfected animals, given the somatic cell information, are discussed. Several extensions of the model are suggested. [less ▲]

Detailed reference viewed: 11 (0 ULiège)
Full Text
Peer Reviewed
See detailExploration isocinétique de l’avant-bras et du poignet. Méthodologie et application à une pathologie tendineuse
Forthomme, Bénédicte ULiege; Croisier, Jean-Louis ULiege; Foidart-Dessalle, Marguerite ULiege et al

in Journal de Traumatologie du Sport (2004), 21(2), 80-87

Relatively little is known about isokinetic profiles of the forearm and wrist muscles. The aims of the study were therefore to prove the reproducibility of the measurements, to establish reference ... [more ▼]

Relatively little is known about isokinetic profiles of the forearm and wrist muscles. The aims of the study were therefore to prove the reproducibility of the measurements, to establish reference concentric and eccentric strength values and to determine the effectiveness of an isokinetic eccentric training model in treating chronic epicondylitis. The concentric and eccentric assessment of healthy male and female subjects allowed the analysis of different parameters: absolute and bodyweight normalized peak torque; bilateral asymmetries and conventional pronator / supinator and flexor / extensor ratios. We have studied the coefficients of variation in a test – retest session. At the same time, 32 patients diagnosed with chronic lateral epicondylitis benefited from an adapted isokinetic eccentric training model (20 to 30 sessions). The absolute reliability in repeated tests procedure of peak torque measurement appeared satisfactory with CV inferior to 12 %. The bilateral asymmetries did not exceed 24 %. PT ratio study reflected the superiority of the PRO and FLE muscles in comparison to the opposite groups. The eccentric rehabilitative model presented a very satisfactory effect on treating chronic epicondylitis with a significant reduction of pain (Visual Analogic Scale), improvement in the ultrasonographic examination (normalized echoic aspect in 53 % of cases) and normalization of maximal isokinetic strength. The isokinetic testing of the forearm pronosupinator muscles and wrist flexor-extensor muscles appeared reproducible. Referential values were proposed for different parameters allowing easier interpretation of pathological cases. The isokinetic eccentric rehabilitative model promoted the epicondylitis treatment. [less ▲]

Detailed reference viewed: 153 (19 ULiège)
Full Text
Peer Reviewed
See detailFièvre chez le cheval adulte : approche diagnostique et clinique
Amory, Hélène ULiege

in Pratique Vétérinaire Equine (2004), 36

Chez le cheval, la cause de la fièvre peut être de nature infectieuse (le plus souvent), néoplasique, inflammatoire ou immune. En pratique, pour localiser le trouble et en déterminer la nature, le ... [more ▼]

Chez le cheval, la cause de la fièvre peut être de nature infectieuse (le plus souvent), néoplasique, inflammatoire ou immune. En pratique, pour localiser le trouble et en déterminer la nature, le vétérinaire aborde un animal souffrant de fièvre en cinq étapes successives : anamnèse ; examen général ; examen clinique approfondi du ou des systèmes qui semblent affectés ; examens cliniques complémentaires ; examens complémentaires de laboratoire. [less ▲]

Detailed reference viewed: 141 (0 ULiège)
Full Text
Peer Reviewed
See detailEffects of a quantitative trait locus for muscle hypertrophy from Belgian Texel sheep on carcass conformation and muscularity
Laville, E.; Bouix, J.; Sayd, T. et al

in Journal of Animal Science (2004), 82(11), 3128-3137

A QTL for muscle hypertrophy has been identified in the Belgian Texel breed. A population of F-2 and backcross lambs created from crosses of Belgian Texel rams with Romanov ewes was studied. Effects on ... [more ▼]

A QTL for muscle hypertrophy has been identified in the Belgian Texel breed. A population of F-2 and backcross lambs created from crosses of Belgian Texel rams with Romanov ewes was studied. Effects on carcass traits and muscle development of the Belgian Texel breed polygenes and Belgian Texel single QTL were compared. In both cases, carcass conformation and muscularity were improved. The Texel polygenic environment improved conformation mainly through changes in skeletal frame shape. Segments were shorter and bone weight lower. Muscles were more compact, shorter, and thicker. The single QTL affected muscle development. Thickness and weight of muscles were increased. Composition in myosin changed toward an increase of fast contractile type. The relative contribution of hind limb joint to carcass weight was increased. Differences in skeletal frame morphology among the three genotypes of the single QTL were small. Conformation scoring was mainly influenced by leg muscularity. Back and shoulder muscle development, which largely contributed to variability of muscularity, were less involved in the conformation scoring. Lastly, the QTL explains a small part of differences between these Belgian Texel and Romanov breeds for conformation or muscle development. A large part of genetic variability remains to be explored. [less ▲]

Detailed reference viewed: 13 (1 ULiège)
Full Text
Peer Reviewed
See detailCompte rendu de La tradizione barese di S. Sabino di Canosa
George, Philippe ULiege

in Revue d'Histoire Ecclésiastique (2004)

Detailed reference viewed: 7 (4 ULiège)
Full Text
Peer Reviewed
See detailDifferential effects of testosterone on protein synthesis activity in male and female quail brain
Dermon, C. R.; Stamatakis, A.; Giakoumaki, S. et al

in Neuroscience (2004), 123(3), 647-666

In Japanese quail, testosterone (T) increases the Nissl staining density in the medial preoptic nucleus (POM) in relation to the differential activation by T of copulatory behavior. The effect of T on ... [more ▼]

In Japanese quail, testosterone (T) increases the Nissl staining density in the medial preoptic nucleus (POM) in relation to the differential activation by T of copulatory behavior. The effect of T on protein synthesis was quantified here in 97 discrete brain regions by the in vivo autoradio-graphic C-14-leucine (Leu) incorporation method in adult gonadectomized male and female quail that had been treated for 4 weeks with T or left without hormone. T activated male sexual behaviors in males but not females. Overall Leu incorporation was increased by T in five brain regions, many of which contain sex steroid receptors such as the POM, archistriatum and lateral hypothalamus. T decreased Leu incorporation in the medial septum. Leu incorporation was higher in males than females in two nuclei but higher in females in three nuclei including the hypothalamic ventromedial nucleus. Significant interactions between effects of T and sex were seen in 13 nuclei: in most nuclei (n=12), T increased Leu incorporation in males but decreased it in females. The POM boundaries were defined by a denser Leu incorporation than the surrounding area and incorporation was increased by T more in males (25%) than in females (15%). These results confirm that protein synthesis in brain areas relevant to the control of sexual behavior can be affected by the sex of the subjects or their endocrine condition and that T can have differential effects in the two sexes. These anabolic changes should reflect the sexually differentiated neurochemical mechanisms mediating behavioral activation. (C) 2003 IBRO. Published by Elsevier Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 24 (1 ULiège)
Full Text
Peer Reviewed
See detailThermo-diffusion revisited: A comparative approach between two recent thermodynamic formalisms
Lebon, Georgy ULiege; Desaive, Thomas ULiege; Colinet, P.

in Journal of Non-Equilibrium thermodynamics (2004), 29(4), 405-415

Extended irreversible thermodynamics and the general equation for the non-equilibrium reversible-irreversible coupling are two thermodynamic theories that have recently received much attention, not only ... [more ▼]

Extended irreversible thermodynamics and the general equation for the non-equilibrium reversible-irreversible coupling are two thermodynamic theories that have recently received much attention, not only from the fundamental but also from the practical point of view. The objective of the present work is to compare the respective merits of these two approaches by emphasising their similarities and differences. To avoid formal and tedious developments, we have applied both formalisms to a concrete problem, namely thermo-diffusion in a binary fluid mixture of nonviscous fluids. [less ▲]

Detailed reference viewed: 17 (2 ULiège)
Full Text
Peer Reviewed
See detailDiscrimination between Bifidobacterium species from human and animal origin by PCR-restriction fragment length polymorphism
Delcenserie, Véronique ULiege; Bechoux, Nathalie ULiege; Leonard, Tamara et al

in Journal of Food Protection (2004), 67(6), 1284-1288

Bifidobacteria are normal intestinal flora in humans and animals. The genus Bifidobacterium includes 31 species of significant host specificity. Taking into account their properties, we proposed to use ... [more ▼]

Bifidobacteria are normal intestinal flora in humans and animals. The genus Bifidobacterium includes 31 species of significant host specificity. Taking into account their properties, we proposed to use bifidobacteria as fecal contamination indicators. PCR-restriction fragment length polymorphism on the 16S rDNA gene was used to distinguish the different Bifidobacterium species. Sixty-four strains belonging to 13 different species were differentiated from animal or human origin using one or two restriction enzymes. Moreover, the primers used were specifics of the Bifidobacterium genus. Therefore, this method made it possible to determine both the presence of bifidobacteria in a sample and its origin of contamination. [less ▲]

Detailed reference viewed: 113 (11 ULiège)
Full Text
Peer Reviewed
See detailCrystal structure of the C47S mutant of human peroxiredoxin 5
Evrard, Christine ULiege; Smeets, Aude; Knoops, Bernard et al

in Journal of Chemical Crystallography (2004), 34

In the crystal structure of the reduced form of the wild-type human peroxiredoxin 5, the presence of a benzoate ion in direct interaction with the peroxidatic cysteine (Cys 47) appeared as a rather ... [more ▼]

In the crystal structure of the reduced form of the wild-type human peroxiredoxin 5, the presence of a benzoate ion in direct interaction with the peroxidatic cysteine (Cys 47) appeared as a rather intriguing feature since it is known that the benzoate ion can play the role of a specific hydroxyl radical scavenger. The crystal structure of the C47S mutant of the same enzyme has been crystallized in the tetragonal system, space group P41212, with a = 65.65 Å, c = 122.04 Å. It confirms the presence of this benzoate ion in spite of the mutation into a serine of the Cys 47 residue to which the benzoate ion was directly linked in the wild-type structure. The benzoate ion seems to be stabilized by hydrophobic contacts on both sides of the aromatic ring. In this matter, the α5 helix, which is specific to peroxiredoxin 5 among mammalian peroxiredoxins, plays an important role. These hydrophobic contacts also allow to suggest why the benzoate ion disappears when the molecule is oxidized. [less ▲]

Detailed reference viewed: 11 (0 ULiège)
Full Text
Peer Reviewed
See detailDiscriminative stimulus effects of ethanol: Lack of interaction with taurine
Quertemont, Etienne ULiege; Grant, Kathleen A.

in Behavioural Pharmacology (2004), 15(7), 495-501

Recent microdialysis studies showed that ethanol administration increases the release of taurine in various rat brain regions, and it was suggested that this increase in extracellular concentrations of ... [more ▼]

Recent microdialysis studies showed that ethanol administration increases the release of taurine in various rat brain regions, and it was suggested that this increase in extracellular concentrations of taurine might mediate some of the neurochemical effects of ethanol. Previous drug discrimination studies showed that positive modulators of the GABA(A) receptor consistently substituted for ethanol discriminative stimulus effects. Since taurine is also believed to modulate GABA(A) receptor activity, this study addressed the hypothesis that taurine mediates the discriminative stimulus effects of ethanol due to GABA(A) activation. Male Long-Evans rats were trained to discriminate water from either 1 or 2 g/kg ethanol. In a first experiment, various taurine doses (0-500 mg/kg) were tested to investigate whether taurine substitutes for ethanol. In a second experiment, rats were pretreated with either 500 mg/kg taurine or an equivalent volume of saline before testing for ethanol discrimination with various ethanol doses (0-2.0 g/kg). The results showed that taurine does not substitute for ethanol at any tested doses. In addition, taurine pretreatments failed to modify the dose-response curve for ethanol discrimination. These results demonstrate that taurine is not directly involved in mediating the discriminative stimulus effects of ethanol. It is therefore very unlikely that the brain release of taurine observed after ethanol administration is implicated in the major pharmacological effects of ethanol, i.e. positive modulation of GABA(A) receptor, that mediate its discriminative stimulus effects. [less ▲]

Detailed reference viewed: 15 (0 ULiège)
Full Text
Peer Reviewed
See detailGas transfer velocities of CO2 in three European estuaries (Randers Fjord, Scheldt and Thames)
Borges, Alberto ULiege; Delille, Bruno ULiege; Schiettecatte, Laure-Sophie et al

in Limnology and Oceanography (2004), 49(5), 1630-1641

We measured the flux of CO2 across the air–water interface using the floating chamber method in three European estuaries with contrasting physical characteristics (Randers Fjord, Scheldt, and Thames). We ... [more ▼]

We measured the flux of CO2 across the air–water interface using the floating chamber method in three European estuaries with contrasting physical characteristics (Randers Fjord, Scheldt, and Thames). We computed the gas transfer velocity of CO2 (k) from the CO2 flux and concomitant measurements of the air–water gradient of the partial pressure of CO2 (pCO2). There was a significant linear relationship between k and wind speed for each of the three estuaries. The differences of the y-intercept and the slope between the three sites are related to differences in the contribution of tidal currents to water turbulence at the interface and fetch limitation. The contribution to k from turbulence generated by tidal currents is negligible in microtidal estuaries such as Randers Fjord but is substantial, at low to moderate wind speeds, in macrotidal estuaries such as the Scheldt and the Thames. Our results clearly show that in estuaries a simple parameterization of k as a function of wind speed is site specific and strongly suggest that the y-intercept of the linear relationship is mostly influenced by the contribution of tidal currents, whereas the slope is influenced by fetch limitation. This implies that substantial errors in flux computations are incurred if generic relationships of the gas transfer velocity as a function of wind speed are employed in estuarine environments for the purpose of biogas air–water flux budgets and ecosystem metabolic studies. [less ▲]

Detailed reference viewed: 330 (10 ULiège)
Full Text
Peer Reviewed
See detailDownregulation of ICAM-1 and VCAM-1 expression in endothelial cells treated by photodynamic therapy
Volanti, Cédric ULiege; Gloire, Geoffrey ULiege; Vanderplasschen, Alain ULiege et al

in Oncogene (2004), 23(53), 8649-8658

Photodynamic therapy (PDT) is a treatment for cancer and several noncancerous proliferating cell diseases that depends on the uptake of a photosensitizing compound followed by selective irradiation with ... [more ▼]

Photodynamic therapy (PDT) is a treatment for cancer and several noncancerous proliferating cell diseases that depends on the uptake of a photosensitizing compound followed by selective irradiation with visible light. In the presence of oxygen, irradiation leads to the production of reactive oxygen species (ROS). A large production of ROS induces the death of cancer cells by apoptosis or necrosis. A small ROS production can activate various cellular pathways. Here, we show that PDT by pyropheophorbide-a methyl ester (PPME) induces the activation of nuclear factor kappa B (NF-kappaB) in HMEC-1 cells. NF-kappaB is active since it binds to the NF-kappaB sites of both ICAM-1 and vascular cell adhesion molecule-1 (VCAM-1) promoters and induces the transcription of several NF-kappaB target genes such as those of IL-6, ICAM-1, VCAM-1. In contrast, expression of ICAM-1 and VCAM-1 at the protein level was not observed, although we measured an IL-6 secretion. Using specific chemical inhibitors, we showed that the lack of ICAM-1 and VCAM-1 expression is the consequence of their degradation by lysosomal proteases. The proteasome and calpain pathways were not involved. All these observations were consistent with the fact that no adhesion of granulocytes was observed in these conditions. [less ▲]

Detailed reference viewed: 50 (11 ULiège)
Full Text
Peer Reviewed
See detailMultispectral imaging of ore minerals in optical microscopy
Pirard, Eric ULiege

in Mineralogical Magazine (2004), 68(2), 323-333

Multispectral imaging of ore minerals under the microscope is a logical extension of quantitative colour analysis and microspectrophotometric analysis of minerals. This paper describes, step by step, how ... [more ▼]

Multispectral imaging of ore minerals under the microscope is a logical extension of quantitative colour analysis and microspectrophotometric analysis of minerals. This paper describes, step by step, how the proper calibration of a scientific video camera can be performed in order to obtain precise reflectance measurements at each pixel within the field of view. After having reviewed the different sources of noise and aberration, practical formulae are presented that allow for the acquisition of a set of images at different wavelengths in the visible spectrum. The advantage of using a multispectral image acquisition system based on narrow bandwidth (10 nm) interference filters is discussed and quantitatively compared to colour imaging using tri-stimulus (red, green, blue) filters. Images taken from major sulphide parageneses are shown as examples of well contrasted multispectral images. Finally, the potential for automatic identification of ore minerals is discussed with reference to supervised multivariate image classification algorithms similar to those used in remote sensing. Additional comments on extending the principles for handling optical anisotropy and developing a multiradial imaging system are made. [less ▲]

Detailed reference viewed: 195 (19 ULiège)
Full Text
Peer Reviewed
See detailMuscular imbalance and acute lower extremity muscle injuries in sport
Croisier, Jean-Louis ULiege

in International SportMed Journal (2004), 5(3), 169-176

Investigating factors associated with muscle strains highlight the multifactorial origin of the injury and the difficulty of identifying isolated or combined factors that caused the injury. Among the ... [more ▼]

Investigating factors associated with muscle strains highlight the multifactorial origin of the injury and the difficulty of identifying isolated or combined factors that caused the injury. Among the numerous causes reported in the literature, only a few have been scientifically associated with injury occurrence, while others have been empirically suggested. Contradictions in articles dealing with muscle strength and imbalance are frequent, and are probably the result of differences in methodology and criteria for patient inclusion. Imbalance in muscle strength commonly refers to abnormal bilateral asymmetry (between homologous groups) and a disruption of the agonist-antagonist ratio. Some authors who focus on a history of hamstring or adductor strains have demonstrated the frequent abnormality of muscle strength and balance by means of isokinetic assessment. Mixed ratios, combining the eccentric performance of “decelerating” muscles (such as the hamstrings) and the concentric performance of “mobiliser” muscles (such as the quadriceps) are suggested and seem relevant. An increased emphasis on eccentric strengthening exercises, particularly for the hamstrings, and ratio correction on the basis of statistically selected cut-offs, significantly reduces the recurrence rate of the injury and lingering complaints upon return-to-sport. Similarly, isokinetic interventions, as a preseason screening tool in sports where there is a high rate of muscle strain injuries, could detect imbalances early and thus promote a preventive strategy. [less ▲]

Detailed reference viewed: 758 (10 ULiège)
Full Text
Peer Reviewed
See detailSurvivin enhances radiation resistance in primary human glioblastoma cells via caspase-independent mechanisms.
Chakravarti, Arnab; Zhai, Gary G; Zhang, Min et al

in Oncogene (2004), 23(45), 7494-506

The observed radioresistance of human glioblastoma multiforme (GBM) poses a major challenge, which, if overcome, may lead to significant advances in the management of this patient population. There is ... [more ▼]

The observed radioresistance of human glioblastoma multiforme (GBM) poses a major challenge, which, if overcome, may lead to significant advances in the management of this patient population. There is accumulating evidence from correlative studies that Survivin expression is associated with increased malignant potential of human gliomas. The purpose of this study was to investigate whether Survivin plays a direct role in mediating radiation resistance in primary human glioma cell lines, and, if so, investigating the underlying mechanisms. Our panel of GBM cell lines included two that were relatively radiation resistant (GM20 and GM21) and two that were more radiation sensitive (GM22 and GM23), which demonstrated differential levels of Survivin expression between the two groups. Through the use of adenoviral vectors containing either dominant-negative (pAd-S(T34A)) or wild-type Suvrivin (pAd-S(WT)), we were able to inactivate or overexpress Survivin, respectively. Our findings suggest that Survivin plays a critical role in mediating radiation resistance in primary GBM cells, in part through suppression of apoptotic cell death via a caspase-independent manner. We have identified novel mechanisms by which Survivin may enhance tumor cell survival upon radiation exposure such as regulation of double-strand DNA break repair and tumor cell metabolism, which were most evident in the radiation-resistant cell lines. These differences in Survivin function both in radiation-resistant vs radiation-sensitive cell lines and in the presence vs absence of radiation exposure warrant further investigation and highlight potentially important mechanisms of radiation resistance in these tumors. [less ▲]

Detailed reference viewed: 20 (0 ULiège)
Full Text
Peer Reviewed
See detailMagnetic resonance imaging of the palmar aspect of the equine podotrochlear apparatus: Normal appearance
Busoni, Valeria ULiege; Snaps, Frédéric ULiege; Trenteseaux, Jacques ULiege et al

in Veterinary Radiology & Ultrasound (2004), 45(3), 198-204

The purpose of this study was to describe the normal magnetic resonance (MR) imaging characteristics of the palmar structures of the equine podotrochlear apparatus by means of retrospective evaluation of ... [more ▼]

The purpose of this study was to describe the normal magnetic resonance (MR) imaging characteristics of the palmar structures of the equine podotrochlear apparatus by means of retrospective evaluation of MR imaging studies of 16 cadaver limbs. The articular aspect of the distal sesamoid bone was not evaluated in this study. Equine digits were imaged with a human knee radiofrequency coil in a 1.5 T magnetic field, using spin echo (SE) T1-weighted, turbo spin echo proton density (TSE PD)-weighted with and without fat saturation (FS), and FS TSE T2-weighted sequences. The limbs were dissected after imaging to validate the absence of gross abnormalities of the flexor aspect of the distal sesamoid bone, of the deep digital flexor tendon, and the distal impar sesamoidean ligament. Seven deep digital flexor tendons were subjected to histologic examination to exclude any microscopic tendon pathology. The anatomic structures of the podotrochlear apparatus were easily identified on MR images. Compact bone of the flexor cortex of the distal sesamoid bone had low intensity signal on all sequences. In 11 digits an increased signal was seen within the thickness of the sagittal eminence of the flexor cortex in SE T1-weighted images and in TSE PD-weighted images without FS. Trabecular bone had a granular appearance and high signal in SE T1-weighted sequences and TSE images without FS. The deep digital flexor tendon had low signal on FS T2-weighted images, while on short echo time sequences (T1- and PD-weighted sequences), the tendon signal varied depending on the relative orientation between its fibers and the static magnetic field. Seven tendons had stippled appearance due to small intratendonous foci of slightly increased signal on transverse T1-weighted images. MR imaging provides a thorough evaluation of the anatomical structure of the podotrochlear apparatus: A good knowledge of the MR imaging appearance and anatomy and an awareness of potential pitfalls will improve diagnostic specificity for the detection of pathologic changes. [less ▲]

Detailed reference viewed: 46 (14 ULiège)
Full Text
Peer Reviewed
See detailEctopic ureters in the dog: literature review and case reports in 3 male dogs
Pollaci, Elsa; Balligand, Marc; Hamaide, Annick ULiege

in Annales de Médecine Vétérinaire (2004), 148(2), 103-109

Ureteral ectopia is a congenital abnormality in which one or both ureters does not open into the bladder. This is the most common cause of urinary incontinence in the immature bitch, but is rarely ... [more ▼]

Ureteral ectopia is a congenital abnormality in which one or both ureters does not open into the bladder. This is the most common cause of urinary incontinence in the immature bitch, but is rarely diagnosed in the male dog. Some breeds are predisposed (Siberian Husky, Labrador, Golden Retriever). Typical clinical signs are a continuous (but sometimes intermittent) leakage of urine since birth, although micturition can be normal. Other associated congenital abnormalities can be present (hydronephrosis, double vagina, cryptorchidism). Diagnostic techniques include excretory urography coupled with a pneumocystography, vaginourethrography, cystoscopy, vaginoscopy, and ultrasonography. Ectopic ureters can be unilateral (most commonly) or bilateral, and they are either intramural or extramural. Surgical correction is the treatment of choice. After a successful surgery, some patients can still show some degree of incontinence, due to the presence of urethral sphincter mechanism incompetence. This residual incontinence can be resolved in the majority of the cases with the use of alpha-adrenergic agents. [less ▲]

Detailed reference viewed: 96 (12 ULiège)
Full Text
Peer Reviewed
See detailHuman recombinant thiamine triphosphatase: purification, secondary structure and catalytic properties
Lakaye, Bernard ULiege; Makarchikov, Alexander F; Wins, Pierre et al

in International Journal of Biochemistry & Cell Biology (2004), 36(7), 1348-1364

Thiamine triphosphate (ThTP) is found in most living organisms and it may act as a phosphate donor for protein phosphorylation. We have recently cloned the cDNA coding for a highly specific mammalian 25 ... [more ▼]

Thiamine triphosphate (ThTP) is found in most living organisms and it may act as a phosphate donor for protein phosphorylation. We have recently cloned the cDNA coding for a highly specific mammalian 25 kDa thiamine triphosphatase (ThTPase; EC 3.6.1.28). As the enzyme has a high catalytic efficiency and no sequence homology with known phosphohydrolases, it was worth investigating its structure and catalytic properties. For this purpose, we expressed the untagged recombinant human ThTPase (hThTPase) in E. coli, produced the protein on a large scale and purified it to homogeneity. Its kinetic properties were similar to those of the genuine human enzyme, indicating that the recombinant hThTPase is completely functional. Mg2+ ions were required for activity and Ca2+ inhibited the enzyme by competition with Mg2+. With ATP as substrate, the catalytic efficiency was 10(-4)-fold lower than with ThTP, confirming the nearly absolute specificity of the 25 kDa ThTPase for ThTP. The activity was maximum at pH 8.5 and very low at pH 6.0. Zn2+ ions were inhibitory at micromolar concentrations at pH 8.0 but activated at pH 6.0. Kinetic analysis suggests an activator site for Mg2+ and a separate regulatory site for Zn2+. The effects of group-specific reagents such as Woodward's reagent K and diethylpyrocarbonate suggest that at least one carboxyl group in the active site is essential for catalysis, while a positively charged amino group may be involved in substrate binding. The secondary structure of the enzyme, as determined by Fourier-transform infrared spectroscopy, was predominantly beta-sheet and alpha-helix. [less ▲]

Detailed reference viewed: 45 (17 ULiège)
Full Text
Peer Reviewed
See detailHiv-1 Gp41 And Gp160 Are Hyperthermostable Proteins In A Mesophilic Environment - Characterization Of Gp41 Mutants
Krell, Tino; Greco, Frédéric; Engel, Olivier et al

in European Journal of Biochemistry (2004), 271(8), 1566-79

HIV gp41(24-157) unfolds cooperatively over the pH range of 1.0-4.0 with T(m) values of > 100 degrees C. At pH 2.8, protein unfolding was 80% reversible and the DeltaH(vH)/DeltaH(cal) ratio of 3.7 is ... [more ▼]

HIV gp41(24-157) unfolds cooperatively over the pH range of 1.0-4.0 with T(m) values of > 100 degrees C. At pH 2.8, protein unfolding was 80% reversible and the DeltaH(vH)/DeltaH(cal) ratio of 3.7 is indicative of gp41 being trimeric. No evidence for a monomer-trimer equilibrium in the concentration range of 0.3-36 micro m was obtained by DSC and tryptophan fluorescence. Glycosylation of gp41 was found to have only a marginal impact on the thermal stability. Reduction of the disulfide bond or mutation of both cysteine residues had only a marginal impact on protein stability. There was no cooperative unfolding event in the DSC thermogram of gp160 in NaCl/P(i), pH 7.4, over a temperature range of 8-129 degrees C. When the pH was lowered to 5.5-3.4, a single unfolding event at around 120 degrees C was noted, and three unfolding events at 93.3, 106.4 and 111.8 degrees C were observed at pH 2.8. Differences between gp41 and gp160, and hyperthermostable proteins from thermophile organisms are discussed. A series of gp41 mutants containing single, double, triple or quadruple point mutations were analysed by DSC and CD. The impact of mutations on the protein structure, in the context of generating a gp41 based vaccine antigen that resembles a fusion intermediate state, is discussed. A gp41 mutant, in which three hydrophobic amino acids in the gp41 loop were replaced with charged residues, showed an increased solubility at neutral pH. [less ▲]

Detailed reference viewed: 27 (7 ULiège)
Full Text
Peer Reviewed
See detailThe matching efficiency of regional labor markets. A stochastic production function estimation: France 1990-1995
Ibourk, Aomar; Maillard, Bénédicte; Perelman, Sergio ULiege et al

in Empirica (2004), (31), 1-25

We evaluate the determinants of aggregate matching efficiency changes through a stochastic translog production frontier model. The efficiency coefficient is represented by a stochastic function of ... [more ▼]

We evaluate the determinants of aggregate matching efficiency changes through a stochastic translog production frontier model. The efficiency coefficient is represented by a stochastic function of variables meant to capture workers and firms characteristics. The model is estimated on French data covering twenty-two regions from March 1990 till February 1995. Our estimates suggest that aggregate matching efficiency has decreased steadily in the early nineties. There are also wide cross-regional differences. On average, about 30% of the variations of efficiency observed across time and regions can be related to changes in the explanatory variables used in the model. The most important explanatory variables are the proportion of youngsters, females and immigrants in the stock of job seekers. Long-term unemployment has a significant negative effect, population density a significant positive one. The huge decline in the proportion of permanent job offers has apparently little effect on matching efficiency. [less ▲]

Detailed reference viewed: 44 (4 ULiège)
Full Text
Peer Reviewed
See detailType trait (co)variance components for five dairy breeds
Wiggans, G. R.; Gengler, Nicolas ULiege; Wright, J. R.

in Journal of Dairy Science (2004), 87(7), 2324-2330

(Co)variance components were estimated for final score and 14 or 15 linear type traits for the Ayrshire, Brown Swiss, Guernsey, Jersey, and Milking Shorthorn breeds. Appraisals from 1995 or later were ... [more ▼]

(Co)variance components were estimated for final score and 14 or 15 linear type traits for the Ayrshire, Brown Swiss, Guernsey, Jersey, and Milking Shorthorn breeds. Appraisals from 1995 or later were used. New estimates were calculated to accommodate changes in scoring of traits and because of a change from multiplicative to additive adjustment for age and lactation stage. The adjustment method was changed for better support of the adjustment for heterogeneous variance within iteration, which was implemented in 2002. The largest changes in heritability were an increase of 0.10 for rump angle for Milking Shorthorns and a decrease of 0.11 for udder depth for Jerseys. The new estimates of (co)variance components should provide improved accuracy of type evaluations, particularly for traits that have had variance changes over time. [less ▲]

Detailed reference viewed: 23 (3 ULiège)
Full Text
Peer Reviewed
See detailTransferrin-Binding Protein B Of Neisseria Meningitidis: Sequence-Based Identification Of The Transferrin-Binding Site Confirmed By Site-Directed Mutagenesis
Renauld-Mongenie, G.; Lins, Laurence ULiege; Krell, T. et al

in Journal of Bacteriology (2004), 186(3), 850-7

A sequence-based prediction method was employed to identify three ligand-binding domains in transferrin-binding protein B (TbpB) of Neisseria meningitidis strain B16B6. Site-directed mutagenesis of ... [more ▼]

A sequence-based prediction method was employed to identify three ligand-binding domains in transferrin-binding protein B (TbpB) of Neisseria meningitidis strain B16B6. Site-directed mutagenesis of residues located in these domains has led to the identification of two domains, amino acids 53 to 57 and 240 to 245, which are involved in binding to human transferrin (htf). These two domains are conserved in an alignment of different TbpB sequences from N. meningitidis and Neisseria gonorrhoeae, indicating a general functional role of the domains. Western blot analysis and BIAcore and isothermal titration calorimetry experiments demonstrated that site-directed mutations in both binding domains led to a decrease or abolition of htf binding. Analysis of mutated proteins by circular dichroism did not provide any evidence for structural alterations due to the amino acid replacements. The TbpB mutant R243N was devoid of any htf-binding activity, and antibodies elicited by the mutant showed strong bactericidal activity against the homologous strain, as well as against several heterologous tbpB isotype I strains. [less ▲]

Detailed reference viewed: 17 (0 ULiège)
Full Text
Peer Reviewed
See detailEffect of reducing energy supply during the finishing of Belgian Blue double-muscled cull cows
Cabaraux, Jean-François ULiege; Dotreppe, Olivier ULiege; Dufrasne, Isabelle ULiege et al

in Animal Science (2004), 79(Part 3), 469-482

A 4-year experiment has been conducted on finishing Belgian Blue cull cows of double-muscled type in order to study the effects of diets containing adequate levels of metabolizable protein, but either ... [more ▼]

A 4-year experiment has been conducted on finishing Belgian Blue cull cows of double-muscled type in order to study the effects of diets containing adequate levels of metabolizable protein, but either normal (NENP), low (LENP) or medium (MENP) levels of metabolizable energy, on animal performance, carcass and meat characteristics, and plasma metabolites and hormones. The LENP diet was offered during the whole (LENP group) or second half of the finishing (NENP-LENP groups), and the MENP diet during the whole finishing (MENP group). The degree of fatness required for the slaughter of animals from NENP groups was close to 4.5 (scale from 0 (very lean) to 5 (very fat)). In each underfed group, the slaughter of the animals was synchronized to that of NENP cows, by degressive degree of fatness. The same duration of finishing was thus obtained for all groups. The experimental feeding strategies reduced the amounts of fat deposited in the carcass and the meat while muscle deposition was remarkably preserved. The proportions of saturated and monounsaturated fatty acids in intramuscular fat were also decreased while their proportions increased in plasma free fatty acids. Plasma insulin levels were also reduced and those of IGF-1 were, surprisingly, maintained. The low energy diet promoted thus the settlement of a discrete lipolytic state while high levels of IGF-1 preserved muscle deposition. This feeding strategy should be evaluated in other breeds of cattle. [less ▲]

Detailed reference viewed: 54 (7 ULiège)
Full Text
Peer Reviewed
See detailDecision tree algorithm for detection of spatial processes in landscape transformation.
Bogaert, Jan ULiege; Ceulemans, R; Salvador-Van Eysenrode, D

in Environmental Management (2004), 33(1), 62-73

Detailed reference viewed: 43 (4 ULiège)
Full Text
Peer Reviewed
See detailEffects of age on plasma metabolites and hormones in finishing Belgian Blue double-muscled cull females
Cabaraux, Jean-François ULiege; Dufrasne, Isabelle ULiege; Istasse, Louis ULiege et al

in Animal Science (2004), 78(Part 2), 229-235

Two groups of 12 Belgian Blue double-muscled cull females were used successively in a 2-year repeated experiment and divided into three groups according to age, allowing four animals per group each year ... [more ▼]

Two groups of 12 Belgian Blue double-muscled cull females were used successively in a 2-year repeated experiment and divided into three groups according to age, allowing four animals per group each year. The aim of the trial was to relate, during the finishing period, the metabolic and endocrine parameters with age. Females were fattened with a diet based on maize silage and were blood sampled on several occasions. The average daily gain (ADG) decreased with the age of the cows. Plasma glucose and triglycerides decreased also with age while the youngest females showed lower concentrations of urea than those older. The composition of plasma non-esterified fatty acids also differed considerably between groups. The hormones that best related with ADG were IGF-1 and insulin. Plasma concentrations of thyroid hormones were lower in the oldest animals. No difference between groups was found for GH. Heifers presented lower concentrations of GH and IGF-1 than those reported elsewhere in fattening bulls of the same breed. It may be concluded that in Belgian Blue double-muscled females, glucose, IGF-1 and insulin are good indicators of the growth potential. Young adult cows presented intermediate characteristics of metabolic and endocrine status that were close either to younger or to older cows. [less ▲]

Detailed reference viewed: 40 (3 ULiège)
Full Text
Peer Reviewed
See detailDes géoindicateurs pour l'analyse et l'évaluation des voies romaines. Etude de la voie romaine Bavay-Tongres.
Gochel, François; Schmitz, Serge ULiege; Ozer, André ULiege

in Bulletin de la Société Géographique de Liège (2004), 44

The Auteur research geoindicators indicating the presence of a Roman road. A geo-indicator is a localised item that accompanies other item less apprehensible. Eight indicators are discussed (straightness ... [more ▼]

The Auteur research geoindicators indicating the presence of a Roman road. A geo-indicator is a localised item that accompanies other item less apprehensible. Eight indicators are discussed (straightness, elevated road, position on the ridge, administrative border, chapel, parcelling, other roman traces, toponym). These geoindicators permit searching Roman road but also determine the more characteristic sectors. [less ▲]

Detailed reference viewed: 155 (7 ULiège)
Full Text
Peer Reviewed
See detailFetal growth restriction: a workshop report
Cetin, I.; Foidart, Jean-Michel ULiege; Miozzo, M. et al

in Placenta (2004), 25(8-9), 753-757

Intrauterine growth restriction (IUGR) is associated with significantly increased perinatal morbidity and mortality as well as cardiovascular disease and glucose intolerance in adult life. A number of ... [more ▼]

Intrauterine growth restriction (IUGR) is associated with significantly increased perinatal morbidity and mortality as well as cardiovascular disease and glucose intolerance in adult life. A number of disorders from genetic to metabolic, vascular, coagulative, autoimmune, as well as infectious, can influence fetal growth by damaging the placenta, leading to IUGR as a result of many possible fetal, placental and maternal disorders. Strict definitions of IUGR and of its severity are needed in order to eventually distinguish among different phenotypes, such as gestational age at onset, degree of growth restriction and presence of hypoxia. This report explores and reviews some of the most recent developments in both clinical and basic research on intrauterine growth restriction, by seeking mechanisms that involve genetic factors, utero-placental nutrient availability and vascular growth factors. New exciting findings on the genomic imprinting defects potentially associated with IUGR, and the placental anomalies associated with the decreased nutrient transport are summarized. Moreover, recent data on angiogenic growth factors as well as new information arising from application of gene chip technologies are discussed. (C) 2004 Elsevier Ltd. All rights reserved. [less ▲]

Detailed reference viewed: 28 (6 ULiège)
Full Text
Peer Reviewed
See detailEffects of the calving number on animal performance, carcass and meat composition in finishing Belgian Blue double-muscled culled females
Cabaraux, Jean-François ULiege; Hornick, Jean-Luc ULiege; Dotreppe, Olivier ULiege et al

in Livestock Production Science (2004), 87(2-3), 161-169

In a 2-year experiment, 66 Belgian Blue (BB) double-muscled culled females have been divided in three groups according to the calving number (heifers-H, cows culled after two calvings-C2 or four calvings ... [more ▼]

In a 2-year experiment, 66 Belgian Blue (BB) double-muscled culled females have been divided in three groups according to the calving number (heifers-H, cows culled after two calvings-C2 or four calvings-C4) and finished on a maize silage-based diet in order to compare animal performance and evolution of carcass and meat characteristics with age. Four females per group were slaughtered on day 0 to assess carcass and meat characteristics of lean animals. The initial and final live weights, the carcass weight and the daily food intake increased with advancing age, while the live weight gain and feed efficiency decreased. The H presented the higher killing-out and muscle proportions and the lower adipose tissue proportion. Their meat was less dark and less red than that of older cows. The lowest protein content and the highest fat content in meat dry matter were found in the C2. In the three groups, the carcass and meat became fatter with finishing process. The amplitude of fat deposition was the highest in C2. It can be concluded that the performance of BB culled females vary with age. The carcass and meat characteristics differ mainly between H and cows, few differences appearing between cows. (C) 2003 Elsevier B.V All rights reserved. [less ▲]

Detailed reference viewed: 55 (7 ULiège)
Full Text
Peer Reviewed
See detailDe prosodie van de tussentaal van tweede-/vreemdetaalleerders: een stand van zaken
Rasier, Laurent ULiege

in Toegepaste taalwetenschap in artikelen (2004), 71

Detailed reference viewed: 16 (2 ULiège)
Full Text
Peer Reviewed
See detailChèvremont, Chyvecourt et Chaudfontaine: histoire d'une configuration toponymique
Boutier, Marie-Guy ULiege

in Bulletin de la Commission Royale de Toponymie et de Dialectologie = Handelingen van de Koninklijke Commissie voor Toponymie en Dialectologie (2004), 76

Detailed reference viewed: 64 (8 ULiège)
Full Text
Peer Reviewed
See detailDe prosodie van het Frans en van het Nederlands: een contrastieve blik
Rasier, Laurent ULiege

in Handelingen van de Koninklijke Zuid-Nederlandse Maatschappij voor Taal-, Letterkunde en Geschiedenis (2004)

Detailed reference viewed: 62 (1 ULiège)