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See detailMise en évidence des zones touchées par la désertification par télédétection a basse résolution au Niger
Hountondji, Yvon ULiege; Ozer, Pierre ULiege; Nicolas, Jacques ULiege

in Cybergeo : Revue Européenne de Géographie = Cybergeo - European Journal of Geography (2004)

In order to identify areas where desertification may have occurred over the last two decades, 109 stations located in three bioclimatic zones of Niger are analyzed. Time series of remote sensing data are ... [more ▼]

In order to identify areas where desertification may have occurred over the last two decades, 109 stations located in three bioclimatic zones of Niger are analyzed. Time series of remote sensing data are well suited to this task. Here, we use time series of NOAA AVHRR normalized difference vegetation index (NDVI) data and rainfall data. In this study, trend analysis is used to identify areas within the biomes from 1981 to 1999 in Niger with apparent land degradation in semi-arid areas. It appears that most of Niger (98%) recorded increasing rainfall while only 76% experienced increasing maximum NDVI. However, the combination of the two variables through the ratio shows a widespread reduction of the rain-use efficiency with non significant trend for the stations located in northern Sahel (p=0.52), highly significant for those located in central Sahel (p=0.00009) and significant in southern Sahel (p=0.041). Overall, 75.3% of the sample recorded a significant reduction of the NDVIMax/RR ratio. Only one station out of four (24.7%) presented a stability of the ratio. These negative trends suggest a progressive diminution of the vegetation productivity as highlighted by the lowering of the NDVIMax/RR ratio. This situation suggest a consistently environmental degradation and that desertification processes continued during the last two decades over most of the Sahelian belt of Niger. [less ▲]

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See detailDynamic And Equilibrium Surface Tensions Of Surfactin Aqueous Solutions
Razafindralambo, Hary ULiege; Thonart, Philippe ULiege; Paquot, Michel ULiege

in Journal of Surfactants and Detergents (2004), 7(1), 41-46

A homologous series of surfactins containing β-hydroxy fatty acids having 13, 14, or 15 carbon atoms were isolated from the supernatant of Bacillus subtilis strain S499 cultures. Their surface-active ... [more ▼]

A homologous series of surfactins containing β-hydroxy fatty acids having 13, 14, or 15 carbon atoms were isolated from the supernatant of Bacillus subtilis strain S499 cultures. Their surface-active properties at the air-water interface were then evaluated. Dynamic surface tension data were analyzed by the relaxation function γt=γm+(γo−γm)/[1+(t/t*)n]. Based on various parameters t*, n, vmax, γm calculated from this equation, the dynamic surface properties of surfactin were found to depend on both bulk concentration and hydrophobic character of the alkyl chain. At low concentrations of surfactin, the dynamic surface tension (γd) decreased with increasing carbon atom number of the surfactin alkyl chain (n=13 to 15). However, at high concentrations, the maximum decrease of 41-4 was achieved by surfactin-C14. In contrast, more strongly hydrophobic alkyl chains in surfactins always enhanced their ability in reducing the equilibrium surface tensions and their aptitude in forming micelles. [less ▲]

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See detailPreparation and in vivo toxicity study of solid lipid microparticles as carrier for pulmonary administration
Sanna, V.; Kirschvink, Nathalie; Gustin, Pascal ULiege et al

in AAPS PharmScitech (2004), 5(2), 27

The purpose of this research was to investigate the effects of processing conditions on the characteristics of solid lipid microparticles (SLM) with a potential application as carriers for pulmonary ... [more ▼]

The purpose of this research was to investigate the effects of processing conditions on the characteristics of solid lipid microparticles (SLM) with a potential application as carriers for pulmonary administration. Compritol ( 5.0% wt/ wt) SLM dispersions were prepared by rotor-stator homogenization, at different surfactant concentrations and emulsification times. The SLM were characterized, in terms of morphology and size, after lyophilization and sterilization by autoclaving process. In vivo assessment was carried out in rats by intratracheal instillation of either placebo or SLM dispersion, and by bronchoalveolar lavage for cytological analysis. Mean particle size of 4 to 5 mum was achieved using 0.3% and 0.4% ( wt/ wt) of emulsifier ( Poloxamer 188) and emulsification times of 2 and 5 minutes. The particles showed spherical shape and smooth surface. The morphology of microparticles, the size, and the size distribution were not substantially modified after lyophilization and sterilization. Total cell counts showed no significant differences between placebo and SLM 0.5% or 2.5% groups. Regarding cytology, percentage of polymorphonuclear neutrophils and macrophages did not significantly differ between groups. These results suggest that a single intratracheal administration of the SLMs does not induce a significant inflammatory airway response in rats and that the SLMs might be a potential carrier for encapsulated drug via the pulmonary route. [less ▲]

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See detailLes accidents ischemiques transitoires: une nouvelle definition.
Moonen, Gustave ULiege; Delcourt, Christian ULiege; Lievens, I. et al

in Revue medicale de Liege (2004), 59(5), 281-5

According to its initial definition, which dates back more than 50 years, a transient ischemic attack (TIA) is a sudden focal neurologic deficit lasting for less than 24 hours, of presumed vascular origin ... [more ▼]

According to its initial definition, which dates back more than 50 years, a transient ischemic attack (TIA) is a sudden focal neurologic deficit lasting for less than 24 hours, of presumed vascular origin, and confined to an area of the brain or eye perfused by a specific artery. Recent data on the pathophysiology of cerebral ischemia and the progress made by the imaging techniques have led an American TIA Working Group to propose a new definition which states that: "A transient ischemic attack is a brief episode of neurologic dysfunction, caused by local brain or retinal ischemia, with clinical symptoms typically lasting less than one hour, and without evidence of cerebral infarction". The advantages and limitations of this new definition, the need for an emergency medical care in the presence of a TIA, the clinical signs associated with this condition, the diagnostic work up, and the differential diagnosis are briefly discussed. A clinical example illustrates the difficulties that can be encountered in a case of TIA. [less ▲]

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See detailLow frequency electromagnetic waves in periodic structures
Guenneau, S.; Nicolet, A.; Geuzaine, Christophe ULiege et al

in International Journal of Applied Electromagnetics and Mechanics (2004), 19

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See detailNMR assignments of the major Cannabinoids and cannabiflavonoids isolated from flowers of Cannabis sativa
Choi, Y. H.; Hazekamp, A.; Peltenburg-Looman, A. M. G. et al

in Phytochemical Analysis (2004), 15(6, NOV-DEC), 345-354

The complete H-1- and C-13-NMR assignments of the major Cannabis constituents, Delta(9)-tetrahydrocannabinol, tetrahydrocannabinolic acid, A-tetrahydrocannabinol, cannabigerol, cannabinol, cannabidiol ... [more ▼]

The complete H-1- and C-13-NMR assignments of the major Cannabis constituents, Delta(9)-tetrahydrocannabinol, tetrahydrocannabinolic acid, A-tetrahydrocannabinol, cannabigerol, cannabinol, cannabidiol, cannabidiolic acid, cannflavin A and cannflavin B have been determined on the basis of one- and two-dimensional NMR spectra including H-1- and (13)-NMR, H-1-H-1-COSY, HMQC and HMBC. The substitution of carboxylic acid on the cannabinoid nucleus (as in tetrahydrocannabinolic acid and cannabidiolic acid) has a large effect on the chemical shift of H-1" of the C5 side chain and 2'-OH. It was also observed that carboxylic acid substitution reduces intermolecular hydrogen bonding resulting in a sharpening of the H-5' signal in cannabinolic acid in deuterated chloroform. The additional aromaticity of cannabinol causes the two angular methyl groups (H-8 and H-9) to show identical H-1-NMR shifts, which indicates that the two aromatic rings are in one plane in contrast to the other cannabinoids. For the cannabiflavonoids, the unambiguous assignments of C-3' and C-4' of cannflavin A and B were determined by HMBC spectra. Copyright (C) 2004 John Wiley Sons, Ltd. [less ▲]

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See detailSelection de bactéries lactiques probiotiques d'origine animale
Bouzaine, T.; El Mejdoub, Thami ULiege; Hamdi, M. et al

in Microbiologie et hygiène alimentaire (2004), 16(46), 24-29

Une collection de bactéries lactiques isolées à partir de la microflore intestinale de poulets de chair a été soumise à plusieurs tests de sélection afin de retenir des souches dites probiotiques. L ... [more ▼]

Une collection de bactéries lactiques isolées à partir de la microflore intestinale de poulets de chair a été soumise à plusieurs tests de sélection afin de retenir des souches dites probiotiques. L'évaluation de leur pouvoir acidifiant a révélé que les souches appartenant aux espèces Lactobacillus rhamnosus produisent environ 0,1 9g/ml d'acide lactique. Les différentes espèces étudiées ont montré une réponse variable à des pH acide, et l'espèce L. rhamnosus présente une capacité de survie même à un pH très bas de l'ordre de 2,0. La résistance au x sels biliaire, est une propriété commune à toutes les souches testées; néanmoins, le taux de croissance dans un milieu additionné de sels biliaires varie d'une espèce à une autre. L'espèce L. rhamnosus possède aussi une activité antimicrobienne remarquable contre des germes pathogènes et non pathogènes. [less ▲]

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See detailEnhanced osteoclast development in collagen-induced arthritis in interferon-gamma receptor knock-out mice as related to increased splenic CD11b(+) myelopoiesis
De Klerck, Bert; Carpentier, Isabelle; Lories, Rick J et al

in Arthritis Research & therapy (2004), 6(3), 220-231

Collagen-induced arthritis (CIA) in mice is accompanied by splenomegaly due to the selective expansion of immature CD11b(+) myeloblasts. Both disease manifestations are more pronounced in interferon-gamma ... [more ▼]

Collagen-induced arthritis (CIA) in mice is accompanied by splenomegaly due to the selective expansion of immature CD11b(+) myeloblasts. Both disease manifestations are more pronounced in interferon-gamma receptor knock-out (IFN-gammaR KO) mice. We have taken advantage of this difference to test the hypothesis that the expanding CD11b(+) splenic cell population constitutes a source from which osteoclast precursors are recruited to the joint synovia. We found larger numbers of osteoclasts and more severe bone destruction in joints of IFN-gammaR KO mice than in joints of wild-type mice. Osteoclast-like multinucleated cells appeared in splenocyte cultures established in the presence of macrophage colony-stimulating factor (M-CSF) and stimulated with the osteoclast-differentiating factor receptor activator of NF-kappaB ligand (RANKL) or with tumour necrosis factor-alpha (TNF-alpha). Significantly larger numbers of such cells could be generated from splenocytes of IFN-gammaR KO mice than from those of wildtype mice. This was not accompanied, as might have been expected, by increased concentrations of the intracellular adaptor protein TRAF6, known to be involved in signalling of RANKL- and TNF-alpha-induced osteoclast formation. Splenocyte cultures of IFN-gammaR KO mice also produced more TNF-alpha and more RANKL than those of wild-type mice. Finally, splenocytes isolated from immunised IFN-gammaR KO mice contained comparatively low levels of pro-interleukin-1beta (pro-IL-1beta) and pro-caspase-1, indicating more extensive conversion of pro-IL-1beta into secreted active IL-1beta. These observations provide evidence that all conditions are fulfilled for the expanding CD11b(+) splenocytes to act as a source of osteoclasts and to be indirectly responsible for bone destruction in CIA. They also provide a plausible explanation for the higher susceptibility of IFN-gammaR KO mice to CIA. [less ▲]

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See detailLandscape research in Belgium
Antrop, Marc; Belayew, Dimitri; Droeven, Emilie ULiege et al

in Belgeo (2004), 2-3

In the federal state Belgium, landscape research evolved from regional geographical monographs to more applied research that focuses upon the specific problems in each of the regions. In the highly ... [more ▼]

In the federal state Belgium, landscape research evolved from regional geographical monographs to more applied research that focuses upon the specific problems in each of the regions. In the highly urbanized Flanders region in the north, aspects of suburbanization and fragmentation are the most important. Landscape research involves geographers, historians, archaeologists, agronomists, foresters, ecologists and nature conservationists all dealing with specific goals and tasks. The integration is mainly achieved in spatial planning. In the Walloon region large areas are still rural and have a large forest cover, while urbanized zones are rather concentrated. Landscape research focuses here mainly upon the rural involving geographers, agronomists and planners. The natural and scenic aspects of the landscape dominate and the study of the historical development of the landscape is less pronounced. In Brussels Capital region little attention is given to landscape aspects, as social and typical urban problems dominate. Consequently, different landscape typologies are used in Belgium. [less ▲]

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See detailRegional model of the Somes-Szamos aquifer (RO-HU)
Drobot, Radu; Jianu, Marilena; Sirbu, Nicolai et al

in Hidrotehnica (2004), 49(9-10), 58-66

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See detailAntimicrobial potential of probiotic or potentially probiotic lactic acid bacteria, the first results of the international European research project PROPATH of the PROEUHEALTH cluster
De Vuyst, L.; Lefteris, M.; Lazlo, A. et al

in Microbial Ecology in Health & Disease (2004), 16

The EU-funded PROPATH project addresses the important health issue of prevention of gastrointestinal disorders through probiotics and prebiotics. Seven European laboratories are co-operating in this ... [more ▼]

The EU-funded PROPATH project addresses the important health issue of prevention of gastrointestinal disorders through probiotics and prebiotics. Seven European laboratories are co-operating in this project, which aims to isolate and characterize the relevant antimicrobial agents to combat Gram-negative bacteria including Helicobacter pylori and Salmonella enterica serovar Typhimurium. In this paper, the first results on the screening for probiotic or potentially probiotic lactobacilli that exhibit antimicrobial activity towards these Gram-negative pathogenic bacteria are presented. Spot-on-lawn assays, well-diffusion assays and time-kill studies were performed among the lactic acid bacteria strains that were either collected from fermented foods and faeces (breast-fed babies, infants and animals) or isolated from commercial products to investigate whether any of the collected strains were inhibiting growth of or were killing certain indicator bacteria. Strains inhibiting the gastrointestinal pathogens mentioned above were found. Evidence has been obtained that compounds different from organic acids are produced. [less ▲]

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See detailGenetic variability of von Willebrand factor and risk of coronary heart disease: the Rotterdam Study.
van der Meer, Irene M.; Brouwers, Geert-Jan; BULK, Saskia ULiege et al

in British journal of haematology (2004), 124(3), 343-7

The von Willebrand factor (VWF) may be causally associated with coronary heart disease (CHD) or merely be a marker of endothelial damage. The G allele of the -1793 C/G promoter polymorphism in the VWF ... [more ▼]

The von Willebrand factor (VWF) may be causally associated with coronary heart disease (CHD) or merely be a marker of endothelial damage. The G allele of the -1793 C/G promoter polymorphism in the VWF gene has been associated with higher plasma levels of VWF. To investigate whether VWF has a causal role in CHD, we designed a case-cohort study, including 352 subjects with CHD and a random cohort (n = 736), and prospectively examined the association of the -1793 C/G polymorphism with CHD in subjects with and without advanced atherosclerosis. All subjects were </=75 years of age and participating in the population-based Rotterdam Study. Atherosclerosis was assessed by the ankle-arm index. Among subjects with advanced atherosclerosis, heterozygous and homozygous carriers of the G allele had a 3.5 (1.2-10.2) and 1.5 (0.4-5.7) fold increased risk of CHD respectively, compared with C/C homozygotes. The hazard ratio was 2.6 (1.0-6.8) for carriers of at least one copy of the G allele versus non-carriers. No associations were found in the absence of advanced atherosclerosis. In conclusion, this study suggests that the G allele of the -1793 C/G polymorphism in the VWF gene is associated with an increased risk of CHD, but only in subjects with advanced atherosclerosis. [less ▲]

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See detailPhysicochemical properties and technological functionality of dietary fibres.
Elleuch; Roiseux, Olivier; Blecker, Christophe ULiege et al

in Food Chemistry (2004), (6), 115-124

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See detailLe systeme de prepaiement au Rwanda (II): adhesion et utilisation des services par les beneficiaires.
Musango, Laurent; Martiny, Patrick; Porignon, Denis ULiege et al

in Sante (Montrouge, France) (2004), 14(2), 101-7

In Rwanda, the Ministry of Health is rebuilding the health sector destroyed during the genocide while trying to guarantee the financial accessibility of the population to the services through the setting ... [more ▼]

In Rwanda, the Ministry of Health is rebuilding the health sector destroyed during the genocide while trying to guarantee the financial accessibility of the population to the services through the setting up of a prepayment scheme. Membership remains low in the three pilot districts where the prepayment scheme was introduced four years before (15,6%). In two of these districts, the curative consultation and maternity utilisation has increased appreciably. The members of the prepayment scheme make greater use of the services than the rest of the population. There is a significantly higher prepayment scheme membership among households with a relatively high income and those with a large family (more than 5 family members). Overall, non-members of the prepayment scheme spend more on health services than members do. There are indications that developing the prepayment scheme would be very useful for the people in Rwanda if specific strategies geared to the poor were set up. [less ▲]

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See detailCirculez, il n'y a rien à voir ! De la vacuité d'une phénoménologie purement matérielle
Leclercq, Bruno ULiege

in Etudes Phénoménologiques (2004), XX(39-40), 123-174

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See detailLes prophètes de la cathédrale de Strasbourg
Van den Bossche, Benoît ULiege

in Bulletin de l'Académie Royale des Sciences, des Lettres et des Beaux-Arts de Belgique. Beaux-Arts (2004), 1-6

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See detailThe effects of emotional salience, cognitive effort and meta-cognitive beliefs on a reality monitoring task in hallucination-prone subjects
Laroi, Frank ULiege; Van der Linden, Martial ULiege; Marczewski, P.

in British Journal of Clinical Psychology [=BJCP] (2004), 43

Objectives. A tendency to externalize internal information on reality monitoring tasks has been documented in psychiatric patients with hallucinations. Furthermore, previous studies suggest that factors ... [more ▼]

Objectives. A tendency to externalize internal information on reality monitoring tasks has been documented in psychiatric patients with hallucinations. Furthermore, previous studies suggest that factors such as the emotional salience of the material, cognitive effort and meta-cognitive beliefs are important contributory factors in this tendency to externalize internal information on reality monitoring tasks. However, few studies have investigated these aspects in hallucination-prone subjects. Also, these factors have never been examined simultaneously. In the following study we wished to examine the effects of emotional salience, cognitive effort and meta-cognitive beliefs on reality monitoring functioning in hallucination-prone subjects. Design. Between-participants group design. Method. One hundred normal subjects were administered a reality monitoring task. Words were presented by the experimenter. After each word, subjects were asked to say the first word that came to their mind. Words varied in terms of emotional valence and cognitive effort (high cognitive effort for words requiring longer latency times to associate a word and vice versa). Following a delay, words were presented consisting of those already presented by the experimenter or the subject (old) and those never presented before (new). For each word, subjects were required to identify whether the word was old or new. If the word was identified as old, subjects were required to identify the source of the word (subject or experimenter). Subjects also completed a questionnaire assessing meta-cognitive beliefs. Results. Subjects were grouped according to their scores on a revised and elaborated version of the Launay-Slade Hallucinations Scale (LSHS). Those with scores within the top 25% were included in the hallucination-prone group (HP) (N = 25), whereas scores within the lower 25% were included in the non-hallucination-prone group (NHP) (N = 25). Results showed that the HP subjects had significantly more source discrimination errors than NHP subjects for self-generated items. In other words, HP subjects tended to misattribute to the experimenter items that they had produced themselves. This pattern was especially marked with emotionally charged material and with words that required more cognitive effort. In addition, HP subjects scored significantly higher on a scale assessing meta-cognitive beliefs compared with NHP subjects. Finally, scores on a scale assessing meta-cognitive beliefs were positively associated with source discrimination errors. Conclusions. These results suggest that cognitive effort, emotional salience and meta-cognitive beliefs all play a prominent role in the externalizing bias in hallucination-prone subjects. The results also provide evidence for the validity of the idea of a continuity between hallucination-prone subjects and psychotic patients with hallucinations on reality monitoring tasks, including a number of contributing factors in the occurrence of hallucinations. [less ▲]

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See detailL’adolescent en fugue : fuir… quoi, pour…quoi ?
Glowacz, Fabienne ULiege; Van de Water, G.; Vettenburg, N.

in Observatoire : Revue d'Action Sociale & Médico-Sociale (2004), 42

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See detailCompte-rendu de l'ouvrage de Chantal Kesteloot: Au nom de la Wallonie et de Bruxelles français. Les origines du FDF
Lanneau, Catherine ULiege

in Bulletin d'Information de l'Association Belge d'Histoire Contemporaine = Mededelingenblad van de Belgische Vereniging voor Nieuwste Geschiedenis (2004), XXVI(3), 11-13

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See detailQuantitative and qualitative hydrogeological study of the alluvial aquifer of Somes-Szamos (RO-HU) NATO SfP Project 973684 SQUASH
Dassargues, Alain ULiege; Lenart, Laszlo; Drobot, Radu

in Hidrotehnica (2004), 49(9-10), 3-7

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See detailA contribution to the moss flora of southern South Africa
Vanderpoorten, Alain ULiege; Barker, N. P.

in Journal of Bryology (2004), 26(Part 3), 230-232

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See detailL'adhésion amélo-dentinaire: Principes et état actuels des connaissances
Gueders, Audrey ULiege; Geerts, Sabine ULiege

in Actualités Dentaires de l'Université de Liège (2004), 34

Cet article passe en revue les procédures d'adhésion amélo-dentinaire et tente de rationnaliser la classification des différents systèmes adhésifs actuellement disponibles sur le marché.

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See detailA comparison of diagnosis of pregnancy in the goat via transrectal ultrasound scanning, progesterone, and pregnancy-associated glycoprotein assays
Gonzalez, Fernando; Cabrera, F.; Batista, M. et al

in Theriogenology (2004), 62(6), 1108-1115

Real-time ultrasound scanning (US) via the transrectal route, progesterone (P4) assay, and pregnancy-associated glycoprotein (PAG) detection can be used to diagnose pregnancy at around 3 weeks after ... [more ▼]

Real-time ultrasound scanning (US) via the transrectal route, progesterone (P4) assay, and pregnancy-associated glycoprotein (PAG) detection can be used to diagnose pregnancy at around 3 weeks after breeding. Although several studies have been carried out to evaluate each of these different methods individually, it is difficult to establish adequate comparisons due to differences, such as the breed of goat, age, and farming conditions, among others. The aim of the present paper is to compare the accuracy of diagnosis of pregnancy using transrectal US, P4 assay and PAG detection at the same time and on the same animals. Canary dairy goats (n = 143) were synchronized with an 11-day fluorogestone acetate (FGA) intravaginal sponge followed by PGF(2 alpha), and eCG 2 days before the FGA withdrawal. Blood samples were collected on Days 20, 22, 24, and 26 after mating to determine P4 and PAG concentrations. Transrectal US examinations were performed at the same time. There were 79 pregnant goats and another 64 non-pregnant. The US via the transrectal method and the determination of PAG concentrations provide very accurate pregnancy diagnosis at 24-26 days after breeding; on the contrary, P4 assay on plasma samples performed on Day 22 after breeding was accurate, in this case, in detecting pregnant animals but did not always detect the non-pregnant does. [less ▲]

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See detailVers des normes francophones pour le Rorschach en système intégré : premiers résultats sur un échantillon de 146 adultes
Sultan, Serge; Andronikof, Anne; Fouques, Damien et al

in Psychologie Française (2004), 49(1), 7-24

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See detailSustained antihypertensive activity of telmisartan compared with valsartan
Lacourcière, Yves; Krzesinski, Jean-Marie ULiege; White, William B. et al

in Blood Pressure Monitoring (2004), 9

Early morning bood pressure (BP) surge and 24h mean BP are linked to target-organ damage and cardiovascular events. Antihypertensive agents should sustain BP control, particularly in the last 6h of the ... [more ▼]

Early morning bood pressure (BP) surge and 24h mean BP are linked to target-organ damage and cardiovascular events. Antihypertensive agents should sustain BP control, particularly in the last 6h of the dosing interval or if dosing is missed. The efficacies of the long half-life telmisartan compared with shorter half-life valsartan in the last 6h of the dosing interval following active treatment and during 24h after a missed dose were compared. [less ▲]

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See detailRéflexions didactiques sur la compréhension en lecture
Dumortier, Jean-Louis ULiege

in Français 2000 (2004), 190-191

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See detailA new test for early pregnancy diagnosis in sheep: Determination of ovine pregnancy associated glycoprotein (ovPAG) concentration by means of a homologous radioimmunoassay
Verberckmoes, S.; Vandaele, Leen; De Cat, S. et al

in Vlaams Diergeneeskundig Tijdschrift (2004), 73(2, MAR-APR), 119-127

Early pregnancy diagnosis is a useful tool in the management of sheep breeding. In this study different methods for pregnancy diagnosis in sheep, including the assessment of ovine Pregnancy-Associated ... [more ▼]

Early pregnancy diagnosis is a useful tool in the management of sheep breeding. In this study different methods for pregnancy diagnosis in sheep, including the assessment of ovine Pregnancy-Associated Glycoproteins (ovPAGs), are briefly discussed. Subsequently, in a field trial the use of transrectal ultrasound is compared with the assessment of the concentration of ovPAGs for early pregnancy diagnosis. At the start of the breeding season in 2002, 192 Texel ewes at 4 different farms were synchronized and afterwards mated or artificially inseminated (AI). At the moment of synchronization (D-14) and at 25 (D25), 35 (D35) and 45 (1345) days after mating/AI, transrectal ultrasound was performed and blood was collected by jugular vein puncture. The ovPAG concentration in the plasma of the ewes was measured by means of a homologous radioimmunoassay (RIA). The specificity of transrectal ultrasound was 85%, and the sensitivity was 92% at D25, 94% at D35 and 95% at D45. The specificity of the homologous RIA was 100%, and the sensitivity was 99% at D25, and 100% at D35 and D45. Higher ovPAG concentrations were detected at D35 and D45 than at D25 (P<0.01). An interesting finding was that within the same breed (Texel), ovPAG concentrations were significantly affected by the farm (P<0.01). In conclusion, determination of ovPAG concentration by means of homologous RIA can be used for early pregnancy diagnosis in sheep and is more reliable than transrectal ultrasound at 25,35 or 45 days of gestation. [less ▲]

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See detailExtensive mast cell degranulation in bovine respiratory syncytial virus-associated paroxystic respiratory distress syndrome
Jolly, Sandra ULiege; Detilleux, Johann ULiege; Desmecht, Daniel ULiege

in Veterinary Immunology and Immunopathology (2004), 97(3-4), 125-136

Bovine respiratory syncytial virus (BRSV) infection is an important cause of outbreaks of respiratory disease among calves. This virus commonly induces mild to severe respiratory signs but, in a ... [more ▼]

Bovine respiratory syncytial virus (BRSV) infection is an important cause of outbreaks of respiratory disease among calves. This virus commonly induces mild to severe respiratory signs but, in a substantial proportion of cases, is also reported to be associated with paroxystic respiratory distress syndrome (PRDS). The pathogenesis of this 'malignant' clinical form has not been fully elucidated. The present study aimed at determining whether mast cell (MC) degranulation plays a role in the physiopathologic cascade leading to the PRDS. Paired serum samples were taken in herds during outbreaks of severe respiratory diseases (acute sera) and 3 weeks after (convalescent sera). Based on seroconversion to BRSV and clinical picture, 67 pairs of sera were selected from calves with a BRSV-associated PRDS for circulating MC tryptase determination. A MC metachromatic score was measured in post-mortem lungs from animals died from a BRSV-associated PRDS (principals) and compared with reference scores obtained from healthy lungs (controls). Levels of tryptase were significantly higher in acute sera (26.6+/-12.4 mug/l) compared to convalescent sera (8.4+/-7.8 mug/l; P < 0.001). Metachromatic scores yielded significantly different results between controls and principals (P < 0.01), demonstrating a significant disappearance of metachromatic granules from lung MCs in principals. Taken together, these data demonstrate the presence of an extensive MC degranulation in BRSV-associated PRDS. (C) 2003 Elsevier B.V. All rights reserved. [less ▲]

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See detailCompte-rendu de Denis Fisette et Sandra Lapointe eds., Aux origines de la phénoménologie
Leclercq, Bruno ULiege

in Philosophiques (2004), 31

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See detailEntretenir, c'est également réparer. Note sous Cass., 19 septembre 2003
Kohl, Benoît ULiege

in Revue de la Faculté de Droit de l'Université de Liège (2004)

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See detailExperimental study of the charring rate of tropical hardwoods
Njankouo, Jacques Michel; Dotreppe, Jean-Claude ULiege; Franssen, Jean-Marc ULiege

in Fire & Materials (2004), 28(1, JAN-FEB), 15-24

This paper describes an experimental investigation of the charring rates of timber. An experimental procedure was designed for assessing the charring rate of 20 specimens exposed to fire in a single test ... [more ▼]

This paper describes an experimental investigation of the charring rates of timber. An experimental procedure was designed for assessing the charring rate of 20 specimens exposed to fire in a single test, with one-dimensional heat transfer conditions. Each test specimen was manufactured by gluing seven laminates together. Four thermocouples were inserted at different depths in four different laminates located in the middle of the test specimen. The test was conducted using a gas-fired furnace and specimens were exposed to the standard ISO 834 fire. In order to evaluate the fire performance of tropical hardwoods, seven different species with densities ranging from 500 to 1000 kg/m(3) were used. For the purpose of verifying the experimental procedure against existing data, two softwood species (spruce and fir) and one European hardwood species (oak) were also examined. Experimental results indicate that the test method and procedure can be used for assessing the charring rate of timber both for softwood and for hardwood species. They also show that the density of wood significantly affects the charring rate and that the values recommended in Eurocode 5 for high densities are somewhat too conservative. Copyright (C) 2004 John Wiley Sons, Ltd. [less ▲]

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See detailLes phénoménologies existentialistes et leur héritage bergsonien
Caeymaex, Florence ULiege

in Annales bergsoniennes (2004), II

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See detailCompte rendu de La tradizione barese di S. Sabino di Canosa
George, Philippe ULiege

in Revue d'Histoire Ecclésiastique (2004)

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See detailRevisiting childhood herpes zoster.
Nikkels, Arjen ULiege; Tassoudji, Nazli ULiege; Pierard, Gérald ULiege

in Pediatric Dermatology (2004), 21(1), 18-23

Herpes zoster is rare in otherwise healthy children, but it is more common in association with immunosuppression. Maternal varicella infection during pregnancy and varicella occurring in the newborn ... [more ▼]

Herpes zoster is rare in otherwise healthy children, but it is more common in association with immunosuppression. Maternal varicella infection during pregnancy and varicella occurring in the newborn represent risk factors for childhood herpes zoster. However, some controversies persist about risk factors, diagnosis, and the natural history of childhood disease. In a 2-year prospective study, 18 children with herpes zoster were clinically diagnosed in outpatient consultations in a hospital dermatology unit. Data about age, dermatome involvement, underlying disease, and history of previous varicella were recorded. Tzanck smears, biopsy specimens, and sera were obtained from 18, 4, and 10 children, respectively. The varicella zoster virus major envelope glycoprotein gE was detected in 16 of 18 smears and all four biopsies. Herpes simplex virus I was demonstrated in one of the smears. The established risk factors for childhood herpes zoster were only found in one child. Evidence for previous full-blown varicella and varicella with few lesions was recorded in 7 and 4 of the 17 immunocompetent children, respectively. No history of varicella was recalled in 6 of 17 cases, although a serologic clue of past varicella infection (IgM negative, IgG positive) was disclosed. Recurrent herpes zoster was diagnosed in one immunocompromised child. Zoster-associated pain was localized and the disease severity remained mild in all children. Established risk factors for childhood herpes zoster were only rarely found in our series of patients. In contrast, unrecognized varicella and varicella with few lesions were frequently recorded and may represent additional risk factors for shingles in childhood. Zosteriform herpes simplex virus infections should be differentiated from childhood herpes zoster, emphasizing the importance of precise viral identification. [less ▲]

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See detailMossbauer spectral study of the magnetocaloric FeMnP1-xAsx compounds
Hermann, Raphaël ULiege; Tegus, O.; Bruck, E. et al

in Physical Review b (2004), 70(21),

The magnetic phase transitions in the FeMnP1-xAsx compounds with x= 0.25, 0.35, 0.45, 0.50, and 0.55, have been studied by iron-57 Mossbauer spectroscopy. The ferromagnetic and antiferromagnetic spectra ... [more ▼]

The magnetic phase transitions in the FeMnP1-xAsx compounds with x= 0.25, 0.35, 0.45, 0.50, and 0.55, have been studied by iron-57 Mossbauer spectroscopy. The ferromagnetic and antiferromagnetic spectra have been analyzed with a model that takes into account the random distribution of the P and As near-neighbor anions of a given iron site. This distribution is a binomial distribution of the contributions to the spectra of each iron with n As near neighbors. A magnetostriction model has been used to characterize the temperature induced paramagnetic to ferromagnetic first-order phase transition and order parameters, eta(F)=2.6, 2.3, 2.0, 1.57, and 1.43 have been obtained for x=0.25, 0.35, 0.45, 0.50, and 0.55, respectively. A detailed phase diagram has been derived from the Mossbauer spectral analysis and reveals a magnetic triple point at x=similar to0.35 and similar to210 K. A model that takes into account the random binomial P and As distribution and the contribution from the iron and manganese magnetic sublattices yields excellent fits of the spectral components assigned to the ferromagnetic and incommensurate antiferromagnetic components for the x=0.25 and 0.35 compounds at all temperatures. [less ▲]

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See detailSymmetry and asymmetry of water ages in a one-dimensional flow
Deleersnijder, Eric; Delhez, Eric ULiege

in Journal of Marine Systems (2004), 48(1-4), 61-66

Hall and Haine [J. Mar. Syst., in press] briefly addressed the problem of estimating the age of irreducible fluid elements or water parcels in a one-dimensional flow with constant velocity and diffusivity ... [more ▼]

Hall and Haine [J. Mar. Syst., in press] briefly addressed the problem of estimating the age of irreducible fluid elements or water parcels in a one-dimensional flow with constant velocity and diffusivity. Herein further developments are achieved on this subject. The age of every water parcel is set to zero at the moment it passes through the point x = 0, where x is an appropriate space coordinate. As time progresses, the age of the water is seen to increase unboundedly upstream of the point x = 0, and tend to the steady-state value \x/u\ downstream of the point x = 0, where a is the water velocity. By contrast, the age of the water parcels that have touched at least once the point x = 0 is symmetric with respect to the point x = 0 is smaller than the water age at any tune and position, and tends to \x/u\ as time progresses. Asymptotic expansions are derived for large times. (C) 2004 Elsevier B.V. All rights reserved. [less ▲]

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See detail'Al de rest is pis'. Het verwaterend enthousiasme van Willem Kloos voor Multatuli's werk
Steyaert, Kris ULiege

in Over Multatuli (2004), 26(53), 49-64

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See detailΗ Ελληνιδα και η εκτρωση: Το πεπρωμενον φυγειν αδυνατον;
Naziri, Despina ULiege

in Εκ των Υστερων (Après-coup) Revue psychanalytique (2004), 12

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See detailEffects of COX-2 inhibitors on ROS produced by Chlamydia pneumoniae-primed human promonocytic cells (THP-1)
Mouithys-Mickalad, Ange ULiege; Deby, Ginette ULiege; Dogné, Jean-Michel ULiege et al

in Biochemical and Biophysical Research Communications (2004), 325(4), 1122-1130

Chronic inflammation through foam cells and macrophages is important in atherosclerosis development, and can be considered as therapeutic targets. Cyclooxygenase and NADPH-oxidase were expressed within ... [more ▼]

Chronic inflammation through foam cells and macrophages is important in atherosclerosis development, and can be considered as therapeutic targets. Cyclooxygenase and NADPH-oxidase were expressed within atherosclerotic lesions. Reactive oxygen species produced by NADPH oxidase were found to trigger the cyclooxygenase-2 expression. The effects of preferential COX-2 inhibitors on ROS produced by Chlamydia-primed human monocytes (THP-1 cells) were evaluated by fluorescence, chemiluminescence, oxymetry, and EPR spin trapping. Fluorescence assays showed an increased production of ROS with Chlamydia versus cells primed by 10(-8) M PMA. COX-2 inhibitors inhibited in a dose-dependent manner the luminol-enhanced CL while ibuprofen and diclofenac increased the chemiluminescence response. By EPR spin trapping, COX-2 inhibitors, ibuprofen, and diclofenac, exhibited a dose-dependent inhibiting effect (10 and 100 muM) on the EPR signal appearance. Our cell model combining EPR, chemiluminescence, and oxymetry appeared relevant to study the modulating effects of preferential COX-2 inhibitors on the cell oxidant activity and chronic inflammatory diseases. (C) 2004 Elsevier Inc. All rights reserved. [less ▲]

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See detailComparative clinicopathological manifestations of human aspergillosis. A review.
Pierard, Gérald ULiege; Arrese Estrada, Jorge ULiege; Quatresooz, Pascale ULiege

in Exogenous Dermatology : Physical, Chemical, Biological (2004), 3

Aspergillus species are important fungi of the environment, some of them being responsible for severe infections. Many distinct diseases form the human aspergillosis spectrum. The pathomechanisms differ ... [more ▼]

Aspergillus species are important fungi of the environment, some of them being responsible for severe infections. Many distinct diseases form the human aspergillosis spectrum. The pathomechanisms differ according to the affected organ and the immune status of the patient. The fungus can be responsible for allergic reactions. It may also act as a saprophytic colonizer of air spaces. Infection may remain limited to the skin and nails. It may also be invasive, particularly in immunocompromised patients, in the lungs, paranasal sinus and gastro-intestinal tract. Hematogeneous disseminated aspergillosis represents another dramatic form of the disease. [less ▲]

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See detailPerho Irmeli, Catalogue of Arabic Manuscripts. Codices Arabici Arthur Christenseniani
Bauden, Frédéric ULiege

in Bulletin Critique des Annales Islamologiques (2004), 20

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See detailInduction of cell proliferation and beta-catenin expression in rat utricles in vitro.
Kim, Tae-Soo; Nakagawa, Takayuki; Lee, Ji-Eun et al

in Acta Oto-laryngologica. Supplementum (2004), (551), 22-5

Limited regenerative response occurs in mammalian vestibular epithelia, although vestibular hair cell regeneration in mammals has been demonstrated under a variety of experimental conditions. Beta-catenin ... [more ▼]

Limited regenerative response occurs in mammalian vestibular epithelia, although vestibular hair cell regeneration in mammals has been demonstrated under a variety of experimental conditions. Beta-catenin is known to play an important role in both cell-cell adhesion and signal transduction associated with cell proliferation. This study evaluated cell proliferation activity in mammalian vestibular epithelia in organotypic culture and examined the involvement of beta-catenin in cell proliferation in vestibular epithelia. After 72 h of culture, utricles with or without induction of cell proliferation were examined. Cell proliferation was induced by brief exposure to forskolin and supplementation with fetal bovine serum. Cell proliferation activity was assessed by bromodeoxyuridine (BrdU) labeling. Immunohistochemistry was employed for analysis of cellular distribution of beta-catenin. In utricles cultured without induction of cell proliferation. BrdU labeling was not found in vestibular epithelia. Expression of beta-catenin was found in the area corresponding to the distribution of adherens junctions in vestibular epithelia. However, BrdU labeling was identified in sensory epithelia of utricles following induction of cell proliferation, although the number of BrdU-positive cells in sensory epithelia was very limited. Accumulation of beta-catenin was occasionally found in proliferating cells in sensory epithelia; however, it was not always found in BrdU-positive cells. The present findings suggest that beta-catenin may play a role in the induction of cell proliferation in mammal vestibular epithelia. [less ▲]

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See detailThe use of enzymes and microorganisms for the production of aroma compounds from lipids
Aguedo, Mario ULiege; Ly, M. H.; Belo, I. et al

in Food Technology and Biotechnology (2004), 42(4), 327-336

Lipids are an important source of aroma compounds. In foods, lipids are degraded or modified by enzymatic activities that are originally present in the raw materials or that develop later due to the ... [more ▼]

Lipids are an important source of aroma compounds. In foods, lipids are degraded or modified by enzymatic activities that are originally present in the raw materials or that develop later due to the growth of microorganisms. Mimicking these natural pathways, some processes have been developed to produce aroma compounds in bioreactors. In this review we describe the production of aroma compounds from different families: lactones, green notes and ionones. We focus on points that are specific to these reactions in heterogeneous media: physicochemical forces involved in the interactions between the substrate, product and biocatalyst, transfers between the phases and, as the degradation of lipids often requires an oxidation step, on the problems of oxygenation of the reactors. [less ▲]

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See detailReal time RBS study of Cu-Sn alloy thermal oxidation by means of a 4He2+ external micro-beam
Mathis, François ULiege; Salomon, Joseph; Moignard, Brice et al

in Nuclear Instruments & Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms (2004), 226

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See detailThe management of rectal cancer in Belgium: a survey of our practice
Vanderick, JEAN ULiege; BEAUDUIN; DENEUFBOURG et al

in Acta gastro-enterologica belgica (2004), 67(1), 9-13

In 1995, a Peer Review Commission Radiotherapy was installed at the initiative of the Belgian Ministry of Health as part of a larger pilot project on quality assurance. This commission was composed of 14 ... [more ▼]

In 1995, a Peer Review Commission Radiotherapy was installed at the initiative of the Belgian Ministry of Health as part of a larger pilot project on quality assurance. This commission was composed of 14 members, 8 radiation oncologists (appointed by the Belgian Association of Radiation Oncology) and 6 physicists (appointed by the Belgian Association of Hospital Physicists). Peer review is only one of the activities within the Quality control of the medical performance aiming to improve quality in diagnostic and therapeutic procedures. Other activities in Quality assurance are development of standards and guidelines, continuous education and measurements of the treatment process. In 1998, the Peer review Commission Radiotherapy has proposed to make a survey of rectal cancer management including diagnostic procedures and therapeutic approaches. More than 1300 questionnaires were sent to the chairman of the 25 Belgian radiotherapy departments, asking them to have it filled in by the radiation oncologist in charge of rectal cancer treatment in their department and to all the known surgeons from a list provided by the Ministry of Health. The paper reports and discuss the results of this survey. [less ▲]

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See detailGenome scan for familial abdominal aortic aneurysm using sex and family history as covariates suggests genetic heterogeneity and identifies linkage to chromosome 19q13.
Shibamura, Hidenori; Olson, Jane M; van Vlijmen-Van Keulen, Clarissa et al

in Circulation (2004), 109(17), 2103-8

BACKGROUND: Abdominal aortic aneurysm (AAA) is a relatively common disease, with 1% to 2% of the population harboring aneurysms. Genetic risk factors are likely to contribute to the development of AAAs ... [more ▼]

BACKGROUND: Abdominal aortic aneurysm (AAA) is a relatively common disease, with 1% to 2% of the population harboring aneurysms. Genetic risk factors are likely to contribute to the development of AAAs, although no such risk factors have been identified. METHODS AND RESULTS: We performed a whole-genome scan of AAA using affected-relative-pair (ARP) linkage analysis that includes covariates to allow for genetic heterogeneity. We found strong evidence of linkage (logarithm of odds [LOD] score=4.64) to a region near marker D19S433 at 51.88 centimorgans (cM) on chromosome 19 with 36 families (75 ARPs) when including sex and the number of affected first-degree relatives of the proband (N(aff)) as covariates. We then genotyped 83 additional families for the same markers and typed additional markers for all families and obtained a LOD score of 4.75 (P=0.00014) with sex, N(aff), and their interaction as covariates near marker D19S416 (58.69 cM). We also identified a region on chromosome 4 with a LOD score of 3.73 (P=0.0012) near marker D4S1644 using the same covariate model as for chromosome 19. CONCLUSIONS: Our results provide evidence for genetic heterogeneity and the presence of susceptibility loci for AAA on chromosomes 19q13 and 4q31. [less ▲]

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See detailApplication of bioencapsulated proteinases and peptides for wound gealing
Markvicheva, E; Dugina, T; Grandfils, Christian ULiege et al

in Chemical Industry (2004), 58(6a), 165-175

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See detailIn vitro evaluation of glutathione peroxidase (GPx)-like activity and antioxidant properties of some Ebselen analogues
Mouithys-Mickalad, Ange ULiege; Mareque-Faez, Juan; Chistiaens, U. et al

in Redox Report : Communications in Free Radical Research (2004), 9(2), 81-87

Four analogues of Ebselen were synthesized and their glutathione peroxidase activity and antioxidant property evaluated and compared to Ebselen. Among the studied compounds, only diselenide [3] exhibited ... [more ▼]

Four analogues of Ebselen were synthesized and their glutathione peroxidase activity and antioxidant property evaluated and compared to Ebselen. Among the studied compounds, only diselenide [3] exhibited both glutathione peroxidase activity and radical-scavenging capability. Compounds [3] and [4] showed a strong inhibitory effect (53% and 43%, respectively) on the lipid peroxidation of linoleic acid compared to Ebselen and selenide derivatives ([1] and [2]) which were less active (28%, 26% and 18% inhibition, respectively). A concentration-dependent inhibitory effect was also found in the model of the formation of ABTS*+ radical cation: 65% and 89% inhibition for compound [3] at 10(-4) M and 5 x 10(-5) M, respectively, and 68% and 90% for compound [4], compared to 14% and 52% inhibition for Ebselen and the diselenides [1] and [2] (29%, 46% and 45%, 68%, respectively). By EPR spin trapping technique, the following inhibitory profile of the Ebselen analogues was observed towards the formation of thiyl radicals: Ebselen = [3]>[1]>[2]>[4]. Studies with compound [3] are in progress on oxidative stress cell models. [less ▲]

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See detailInfluence of SFC, microstructure and polymorphism on texture (hardness) of binary blends of fats involved in the preparation of industrial shortenings
Danthine, Sabine ULiege; Deroanne, Claude ULiege

in Food Research International (2004), 37(10), 941-948

Several binary blends of vegetable oils commonly used in industrial shortenings (i.e., palm oil (PO), hydrogenated palm oil (HPO), soybean oil (SO), hydrogenated soybean oil (HSO), low-erucic acid ... [more ▼]

Several binary blends of vegetable oils commonly used in industrial shortenings (i.e., palm oil (PO), hydrogenated palm oil (HPO), soybean oil (SO), hydrogenated soybean oil (HSO), low-erucic acid rapeseed oil (LERO), hydrogenated low-erucic acid rapeseed oil (HLERO)) were studied for their physical properties such as solid fat content (SFC) by nuclear magnetic resonance (NMR) and textural properties (hardness). Microstructure was also observed by microscopy in order to explain the variability in hardness for samples having the same SFC values. The blends studied by microscopy were the following: HSO, HPO and HLERO diluted in LERO. For these three blends which had the same SFC the level of network structure was different. HSO diluted in LERO had more crystals, closer to each other and overlapped. This can explain that HSO has a higher hardness than HPO or HLERO, for a same SFC value, when diluted in LERO. Polymorphism was also observed by powder X-ray diffraction. The variability in hardness for samples having the same SFC is due to various crystal types and/or network structures that are formed upon crystallization of hard fats. This work demonstrates that for binary blends of studied oils, changes in the hardness are controlled mostly by the SFC, polymorphism and also by the material's microstructure. (C) 2004 Elsevier Ltd. All rights reserved. [less ▲]

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See detailEntrevista a Rafael Gutiérrez Girardot
Mogollon Zapata, Juan Manuel ULiege; Gutiérrez, Girardot

in Revista Teoría, Historia, Crítica (2004), 6

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See detailCaspase-8-dependent HER-2 cleavage in response to tumor necrosis factor alpha stimulation is counteracted by nuclear factor kappa B through c-FLIP-L expression
Benoit, Valérie; Chariot, Alain ULiege; Delacroix, Laurence ULiege et al

in Cancer Research (2004), 64(8), 2684-2691

The oncoprotein HER-2/neu is a prosurvival factor, and its overexpression has been correlated with poor prognosis in patients with breast cancer. We report that HER-2 is a new substrate for caspase-8 and ... [more ▼]

The oncoprotein HER-2/neu is a prosurvival factor, and its overexpression has been correlated with poor prognosis in patients with breast cancer. We report that HER-2 is a new substrate for caspase-8 and that tumor necrosis factor alpha (TNF-alpha) stimulation leads to an early caspase-8-dependent HER-2 cleavage in MCF7 A/Z breast adenocarcinoma cells defective for nuclear factor kappaB (NFkappaB) activation. We show that the antiapoptotic transcription factor NFkappaB counteracts this cleavage through induction of the caspase-8 inhibitor c-FLIP. Our results also demonstrate that this HER-2 cleavage contributes to the TNF-alpha-induced apoptosis pathway because ectopic expression of an uncleavable HER-2 protects NFkappaB-defective cells against TNF-alpha-mediated cell death. Therefore, we propose an original model in which NFkappaB exerts a new antiapoptotic function by counteracting TNF-alpha-triggered cleavage of the HER-2 survival factor. [less ▲]

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See detailAcute phase proteins assessment for an early selection of treatments in growing calves suffering from bronchopneumonia under field conditions
Humblet, Marie-France ULiege; Coghe, J.; Lekeux, Pierre ULiege et al

in Research in Veterinary Science (2004), 77(1), 41-47

Blood samples were taken from calves with respiratory disease the first day of examination for determination of the serum concentration of haptoglobin, fibrinogen, alpha-2- and gamma-globulins, and ... [more ▼]

Blood samples were taken from calves with respiratory disease the first day of examination for determination of the serum concentration of haptoglobin, fibrinogen, alpha-2- and gamma-globulins, and albumin. A clinical examination was performed daily for the duration of the disease. The animals were retrospectively classified in two categories: those animals requiring no treatment or antibiotics alone (group A), and antibiotics associated to anti-inflammatory drugs (group B). The serum proteins were tested in order to check whether they were able to distinguish, on the first day of clinical examination, between calves requiring anti-inflammatory treatment (group B) or not (group A). About 80% of calves were properly classified in both groups by the combined use of the two serum proteins haptoglobin and fibrinogen: these two proteins, and especially haptoglobin, were useful for the identification of calves requiring an anti-inflammatory treatment. [less ▲]

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See detailDecision tree algorithm for detection of spatial processes in landscape transformation.
Bogaert, Jan ULiege; Ceulemans, R; Salvador-Van Eysenrode, D

in Environmental Management (2004), 33(1), 62-73

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See detailAgir de manière socialement responsable: la richesse d'une approche par les parties prenantes
Xhauflair, Virginie ULiege

in Entreprise Ethique (2004), 21(octobre), 105-111

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See detailThe membrane form of the DNA repair protein Ku interacts at the cell surface with metalloproteinase 9.
Monferran, Sylvie; Paupert, Jenny ULiege; Dauvillier, Stephanie et al

in The EMBO journal (2004), 23(19), 3758-68

The Ku heterodimer (Ku70/Ku80) plays a central role in DNA double-strand breaks repair. Ku is also expressed on the cell surface of different types of cells where its function remains poorly understood ... [more ▼]

The Ku heterodimer (Ku70/Ku80) plays a central role in DNA double-strand breaks repair. Ku is also expressed on the cell surface of different types of cells where its function remains poorly understood. From a yeast two-hybrid screen, we have identified a specific interaction between the core region of Ku80 and the hemopexin domain of metalloproteinase 9 (MMP-9), a key enzyme involved in the degradation of extracellular matrix (ECM) components. Ku associates with MMP-9 on the surface of leukemic cells as demonstrated by co-immunoprecipitation experiments in membrane extracts and double-label immunofluorescence studies. In normal and tumoral migratory cells, Ku80 and MMP-9 colocalize at the periphery of leading edge of cells and cellular invasion of collagen IV matrices was blocked by antibodies directed against Ku70 or Ku80 subunits as well as by Ku80-specific antisense oligonucleotides. Our results indicate that Ku and MMP-9 interact at the cell membrane of highly invasive hematopoietic cells of normal and tumoral origin and document the unexpected importance of the membrane-associated form of Ku in the regulation of ECM remodelling. [less ▲]

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See detailAccuracy of transrectal ultrasonography for determination of pregnancy in sheep: effect of fasting and handling of the animals
Karen, Aly; Szabados, K.; Reiczigel, J. et al

in Theriogenology (2004), 61(7-8), 1291-1298

The present study was performed to investigate the effect of previous fasting and lifting of the abdomen of the ewes during transrectal ultrasonographic scanning on the results of early pregnancy ... [more ▼]

The present study was performed to investigate the effect of previous fasting and lifting of the abdomen of the ewes during transrectal ultrasonographic scanning on the results of early pregnancy diagnosis. Ewes of four flocks (A, B, C and D; all Awassi x Merino ewes, n = 1247) aged 0.7-10 years were used in this study. These ewes were estrus synchronized and artificially inseminated. From 2 weeks later onwards, fertile rams were kept with the ewes of flocks A, B and C (n = 949) for natural breeding, while ewes of flock D (n = 298) were re-inseminated 17 days later. Transrectal ultrasonography (5 MHz) was carried out in ewes of flocks A, B and C on four separate occasions but only once in ewes of flock D. For final analysis, animals were divided over two groups: ewes of Group 1 (n = 949 scans) were scanned in a standing position within the milking parlor. Animals of Group 2 (n = 764 scans) were scanned by the same operator and with the same scanning technique, but these ewes were fasted for 12 h prior to scanning and the abdominal wall was lifted, just in front of the udder during scanning. The sensitivity of the test for diagnosing pregnancy at Days 18-24, 25-30, 31-40 and 41-50 was 21.8, 32.3, 63.3 and 50% in Group 1, and 46, 92.5, 92.3 and 96.8% in Group 2, respectively. Only within Group 1, the sensitivity of the test was higher in young ewes (0.7-2 years) than in older ones (>2-10 years). Significant differences were observed at scan periods Days 18-24 and Days 4150 of gestation. It is concluded that, fasting prior to scanning and lifting the abdomen during scanning significantly improve the accuracy of transrectal ultrasonographic pregnancy diagnosis in Awassi x Merino ewes. [less ▲]

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See detailSimulated polymer stretch in a turbulent flow using Brownian dynamics
Terrapon, Vincent ULiege; Dubief, Yves; Moin, Parviz et al

in Journal of Fluid Mechanics (2004), 504

We examine the phenomenon of polymer drag reduction in a turbulent flow through Brownian dynamics simulations. The dynamics of a large number of single polymer chains along their trajectories is ... [more ▼]

We examine the phenomenon of polymer drag reduction in a turbulent flow through Brownian dynamics simulations. The dynamics of a large number of single polymer chains along their trajectories is investigated in a Newtonian turbulent channel flow. In particular, the FENE, FENE-P and multimode FENE models with realistic parameters are used to investigate the mechanisms of polymer stretching. A topological methodology is applied to characterize the ability of the flow to stretch the polymers. It is found using conditional statistics that at moderate Weissenberg number Wi the polymers, that are stretched to a large fraction of their maximum extensibility, have experienced a strong blaxial extensional flow. When Wi is increased other flow types can stretch the polymers but the few highly extended molecules again have, on average, experienced a biaxial extensional flow. Moreover, highly extended polymers are found in the near-wall regions around the quasi-streamwise vortices, essentially in regions of strong biaxial extensional flow. [less ▲]

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See detailAn energy-momentum conserving algorithm for non-linear hypoelastic constitutive models
Noels, Ludovic ULiege; Stainier, Laurent ULiege; Ponthot, Jean-Philippe ULiege

in International Journal for Numerical Methods in Engineering (2004), 59(1), 83-114

This paper presents an extension of the energy momentum conserving algorithm, usually developed for hyperelastic constitutive models, to the hypoelastic constitutive models. For such a material no ... [more ▼]

This paper presents an extension of the energy momentum conserving algorithm, usually developed for hyperelastic constitutive models, to the hypoelastic constitutive models. For such a material no potential can be defined, and thus the conservation of the energy is ensured only if the elastic work of the deformation can be restored by the scheme. We propose a new expression of internal forces at the element level which is shown to verify this property. We also demonstrate that the work of plastic deformation is positive and consistent with the material model. Finally several numerical applications are presented. Copyright (C) 2003 John Wiley Sons, Ltd. [less ▲]

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See detailApplication of molecular modeling to the study of cyproterone acetate stability in the presence of cyclodextrin derivatives
Henry de Hassonville, Sandrine; Dive, Georges ULiege; Evrard, Brigitte ULiege et al

in Journal of Drug Delivery Science and Technology (2004), 14(5, SEP-OCT), 357-362

The ability of cyclodextrins (CDs) to increase the solubility of cyproterone acetate (CPA) was previously shown by phase-solubility and NMR studies [1]. In the present work, the influence of various CDs ... [more ▼]

The ability of cyclodextrins (CDs) to increase the solubility of cyproterone acetate (CPA) was previously shown by phase-solubility and NMR studies [1]. In the present work, the influence of various CDs on the stability of CPA was studied in pH 6 and pH 8 aqueous solutions at 25degreesC. Different CDs were tested: hydroxypropyl-beta-cyclodextrin (HPbetaCD), randomly methylated beta-cyclodextrin (RAMEB), hydroxypropyl-gamma-cyclodextrin (HPgammaCD) and gamma-cyclodextrin (gammaCD). At pH 6, the presence of these CDs reduces the degradation of CPA. Nevertheless, at pH 8, the gamma-CD derivatives are ineffective against the degradation of CPA, whereas the beta-CD derivatives (HPbetaCD and RAMEB) allow decreasing CPA hydrolysis. Molecular modeling was performed to theoretically calculate some of the most energetically favorable conformations for gamma-CD and RAMEB complexes with CPA. The position of the ester group in the CD caivity seems to be the most important factor influencing the hydrolysis of CPA. Other factors, such as the size of the cavity, the substitution of the CD hydroxyls and the stability constant also have a strong incidence on CPA stability. [less ▲]

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See detailComparison of steam and nitrogen in the physical deacidification of soybean oil
Decap, Philippe; Danthine, Sabine ULiege; Vanbrabant, Béatrice et al

in Journal of the American Oil Chemists' Society (2004), 81(6), 611-617

Deacidification in physical refining is one of the most sensitive steps in refining edible vegetable oils because of its large impact on the quality of the oil. The removal of volatile compounds such as ... [more ▼]

Deacidification in physical refining is one of the most sensitive steps in refining edible vegetable oils because of its large impact on the quality of the oil. The removal of volatile compounds such as FFA is accomplished at elevated temperatures and a high vacuum with a stripping gas, usually steam. The aim of this work was to verify, at the laboratory level, the advantages of using an alternative stripping gas, nitrogen, instead of steam. An ideal vapor-liquid equilibrium model (lVLE) was used to compare the stripping capacities of steam and nitrogen and to analyze the effects of various operational parameters (temperature, pressure, amount of stripping gas) on the residual acidity of the oil. There was no clear evidence that nitrogen showed a higher capacity to strip FFA than steam. The IVLE model seemed suitable to describe FFA laboratory distillation by using steam or nitrogen, provided the final residual content of FFA was not too low. [less ▲]

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See detailApplication of data mining to optimize settings for generator tripping and load shedding system in emergency control at Hydro-Quebec
Huang, J. A.; Harrison, S.; Vanier, G. et al

in COMPEL (2004), 23(1 Sp. Iss. SI), 21-34

This paper describes the on-going work done by Hydro-Quebec to optimize the settings of automatic devices installed in its main power plants to maintain secure operation under extreme contingencies. The ... [more ▼]

This paper describes the on-going work done by Hydro-Quebec to optimize the settings of automatic devices installed in its main power plants to maintain secure operation under extreme contingencies. The automatic generator tripping and load shedding system (RPTC) described in this paper is installed at the Churchill Falls hydroelectric power plant (5,500 MW) in Labrador. Data mining techniques such as decision trees and regression trees have been used. Real time snapshots of the Hydro-Quebec power system collected over a 5 year period have been used to generate large amounts of results by transient stability simulations. The processing of these data has been done using software developed by the University of Liege. This approach gives the most relevant parameters and finds optimal settings for the RPTC system, minimizing the number of tripped generator units while maintaining the same performance in terms of security coverage. New operation rules can thus be established. [less ▲]

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See detailDiet-induced obesity and reduced skin cancer susceptibility in matrix metalloproteinase-19 deficient mice
Pendas, A. M.; Folgueras, A. R.; LLano, E. et al

in Molecular & Cellular Biology (2004), 24(12), 5304-13

Matrix metalloproteinase 19 (MMP-19) is a member of the MMP family of endopeptidases that, in contrast to most MMPs, is widely expressed in human tissues under normal quiescent conditions. MMP-19 has been ... [more ▼]

Matrix metalloproteinase 19 (MMP-19) is a member of the MMP family of endopeptidases that, in contrast to most MMPs, is widely expressed in human tissues under normal quiescent conditions. MMP-19 has been found to be associated with ovulation and angiogenic processes and is deregulated in diverse pathological conditions such as rheumatoid arthritis and cancer. To gain further insights into the in vivo functions of this protease, we have generated mutant mice deficient in Mmp19. These mice are viable and fertile and do not display any obvious abnormalities. However, Mmp19-null mice develop a diet-induced obesity due to adipocyte hypertrophy and exhibit decreased susceptibility to skin tumors induced by chemical carcinogens. Based on these results, we suggest that this enzyme plays an in vivo role in some of the tissue remodeling events associated with adipogenesis, as well as in pathological processes such as tumor progression [less ▲]

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See detailAnalysis of isokinetic parameters in the development of anterior knee pain syndrome: A prospective study in a military setting
Van Tiggelen, Damien; Witvrouw, Erik; Coorevits, Pascal et al

in Isokinetics & Exercise Science (2004), 12(4), 223-228

Objectives: To explore the role of muscular strength and imbalance as predisposing factors in the development of anterior knee pain syndrome (AKPS). Methods: 96 male military recruits without history of ... [more ▼]

Objectives: To explore the role of muscular strength and imbalance as predisposing factors in the development of anterior knee pain syndrome (AKPS). Methods: 96 male military recruits without history of knee pain volunteered for the study. Each volunteer underwent an isokinetic test prior to the start of a strenuous training program (approximately 8 to 12 hours/day for 6 weeks). The isokinetic test consisted of concentric contractions of the knee flexors and extensors at 60degrees/s and 240degrees/s. A detailed history and clinical examination of the patellofemoral joint was performed on each recruit. Independent sample t-tests were used to compare the isokinetic muscle parameters in recruits who developed AKPS during the training (pathological group) and in those who did not (control group). Binary logistic regression analysis was used to define the predictive outcome of anthropometrics and the isokinetic parameters for the development of AKPS. Results: 31 recruits developed AKPS. Absolute and bodyweight normalized peak extensor torque at 60degrees/s was significantly lower in the pathological group in comparison to the control group. Significant lower peak torque/BMI (Body Mass Index) were also indicated at both velocities. Recruits who developed AKPS had a shorter stature. No regression model could be set up to give any predictive value to the analyzed parameters. Conclusions: Recruits with shorter stature and lower quadriceps strength are more prone to develop AKPS during BMT. However, as the etiology of AKPS is multifactorial these parameters alone may not suffice to predict the occurrence of this pathology. On the other hand, the results of this study emphasize the importance of the reinforcement of quadriceps strength in the treatment and prevention of AKPS. [less ▲]

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See detailBack to Earth - Ballads and (Bio)diversity
Peere, Isabelle ULiege

in B·A·S·I·S: Ballads and Songs - International Studies (2004)

Introduction à une collection de 27 contributions

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See detailInternational Conference on Vision Systems
Crowley, James; Piater, Justus ULiege

in Machine Vision and Applications (2004), 16(1),

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See detailModave/Modave : Fouilles préhistoriques au site du Trou Al'Wesse
Miller, Rebecca ULiege; Otte, Marcel ULiege

in Chronique de l'Archéologie Wallonne (2004), 12

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See detailEvaluation of population density of Pichia anomala strain K and Candida oleophila strain O and their protection against Penicillium expansum Link on apples.
Lahlali, Rachid; Jijakli, Haissam ULiege

in Bulletin OILB/SROP = IOBC/WPRS Bulletin (2004), 27(8), 341-346

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See detailL'image du mois. Un courant d'air.
ROUSSEAU, Anne-Françoise ULiege; CANIVET, Jean-Luc ULiege; CAMPOLINI, Christophe

in Revue Médicale de Liège (2004), 59(10), 550-551

Portal venous gas is a rare radiological symptom related to several possible causes. Its severity is only correlated with the severity of the primary disease. We report the case of a portal pneumatose ... [more ▼]

Portal venous gas is a rare radiological symptom related to several possible causes. Its severity is only correlated with the severity of the primary disease. We report the case of a portal pneumatose. The diagnosis was made by ultrasound and CT scan. [less ▲]

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See detailEffect of hypoxia and reoxygenation on gene expression and response to interleukin-1 in cultured articular chondrocytes.
Martin, G.; Andriamanalijaona, R.; Grassel, S. et al

in Arthritis and Rheumatism (2004), 50(11), 3549-60

OBJECTIVE: To determine the effects of hypoxia and reoxygenation on the metabolism of chondrocytes and their response to interleukin-1beta (IL-1beta). The study included activation of hypoxia-inducible ... [more ▼]

OBJECTIVE: To determine the effects of hypoxia and reoxygenation on the metabolism of chondrocytes and their response to interleukin-1beta (IL-1beta). The study included activation of hypoxia-inducible factor 1 (HIF-1), NF-kappaB, and activator protein 1 (AP-1) transcription factors, expression of matrix components and metalloproteases and transforming growth factor beta (TGFbeta) and TGFbeta receptors, and production of nitric oxide (NO) and prostaglandin E(2) (PGE(2)). METHODS: Bovine articular chondrocytes (BACs) were cultured to confluency in either 5% O(2) (hypoxia) or 21% O(2) (normoxia) in media supplemented with 10% fetal calf serum (FCS). BACs were preincubated for 18 hours in media with 1% FCS only and then incubated for 24 hours in the presence of IL-1beta. For reoxygenation experiments, cells were treated in the same way in 5% O(2), except that cultures were transferred to normal atmospheric conditions and used after 4 hours for RNA extraction or after 30 minutes for cytoplasmic or nuclear protein extraction. RESULTS: In hypoxic and reoxygenated chondrocytes, we observed strong DNA binding of HIF-1. IL-1beta-induced DNA binding of NF-kappaB and AP-1 was significantly higher in hypoxic and reoxygenated cultures than in normoxia. Greater activation of the MAPKs was also observed with IL-1beta treatment in hypoxia compared with normoxia. Steady-state levels of type II collagen and aggrecan core protein messenger RNA (mRNA) were decreased by IL-1beta in all instances. Matrix metalloprotease 1 (MMP-1) and MMP-3 mRNA were increased by IL-1beta in normoxia and hypoxia, whereas only MMP-3 mRNA was enhanced in reoxygenated cultures. The MMP-2 mRNA level was not significantly affected by IL-1beta in normoxia or hypoxia, whereas it was enhanced in reoxygenated cultures. MMP-9 mRNA was dramatically decreased by IL-1beta only in low oxygen tension. Tissue inhibitor of metalloproteinases 1 (TIMP-1) message was significantly enhanced by the cytokine in most instances, whereas TIMP-2 message was markedly decreased by IL-1beta in reoxygenated cultures. Stimulation of TGFbeta1 expression by IL-1beta was observed only in normal atmospheric conditions. One of the more striking findings of the study was the greater stimulating effect of IL-1beta on NO production observed in hypoxia, which was much higher than in normoxia, whereas the reverse was observed for IL-1beta-induced PGE(2) production. CONCLUSION: Oxygen level and reoxygenation stress significantly modulate gene expression and the response of articular chondrocytes to cytokines such as IL-1beta. In hypoxic conditions, which mimic the in vivo condition of cartilage, the effects of IL-1beta on both synthesis and degradative processes are significantly different from those in normoxia, conditions that are unlikely encountered by chondrocytes in a normal state. In low oxygen tension, high IL-1beta-induced NO production is associated with a significant decrease in PGE(2) synthesis. These data should influence our concept of the role of oxygen in the pathophysiology of joint disease and may help define the best conditions in which to develop bioartificial cartilage. [less ▲]

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See detailUne bouche en or
Dezfoulian, Bita ULiege; Henno, Audrey ULiege; Jason, Françoise ULiege et al

in Revue Française d'Allergologie et d'Immunologie Clinique (2004), 44

Contact dermatitis to gold has rarely been reported. This precious metal is generally considered as inert, insoluble and resistant to corrosion. Nevertheless, gold salts have a strong potential for ... [more ▼]

Contact dermatitis to gold has rarely been reported. This precious metal is generally considered as inert, insoluble and resistant to corrosion. Nevertheless, gold salts have a strong potential for sensitization. This condition can occur after contact with gold jewellery and dental alloys, after systemic therapy with gold salts and after occupational contact. The lesions may be expressed as contact dermatitis on the face, ear, neck and/or fingers, and as lichen planus and/or lichenoid stomatitis. The dermatitis is usually not very irritating and the lesions are rarely persistent. Diagnosis is based on the clinical history and examination, on the nature of the exposure sources, and on the results of patch tests with gold sodium thiosulfate (GSTS) at 0.5% in petrolatum. The patch test is read on days 2 and 3 and again after 1 and 3 weeks. Allergen avoidance can be expensive and tiresome, and improvement is not guaranteed.We report the case of a female patient who came to us complaining of burning in her mouth. She had polymetallism and lichenoid lesions facing gold tooth crowns. Patch tests were positive to GSTS at 72 h and at 1 week. Replacement of the gold crowns led to total disappearance of her symptoms within 1 year. Local factors, including humidity, temperature, acid pH, abrasion and contact with substance such as amino acids, bring about the liberation of the sensitizing metallic salts, which may be enhanced by galvanic corrosion secondary to the polymetallism. [less ▲]

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See detailEfficacy assessment of Candida oleophila (strain O) and Pichia anomala (strain K) against major postharvest diseases of citrus fruits in Morocco.
Lahlali, R.; Serrhini, M. N.; Jijakli, Haissam ULiege

in comm. appl. biol. sci. Ghent University (2004), 69(4), 601-609

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See detailLe site du Trou Al'Wesse (comm. de Modave) : Campagne de fouille 2004
Miller, Rebecca ULiege; Zwyns, Nicolas; Otte, Marcel ULiege

in Notae Praehistoricae (2004), 24

This article present the discovery context of Neolithic ceramic sherds in stratum 4 (formerly attributed to the Late Mesolithic) at Trou Al'Wesse. The vertical distribution of the archaeological material ... [more ▼]

This article present the discovery context of Neolithic ceramic sherds in stratum 4 (formerly attributed to the Late Mesolithic) at Trou Al'Wesse. The vertical distribution of the archaeological material and stratigraphic data demonstrate that these sherds do not belong to the Mesolithic assemblage. Post-depositional processes in front of the cave entrance have reworked these sherds and Mesolithic lithic artifacts. The stratigraphy also shows that, against the walls, there is no mixture between the two occupations. [less ▲]

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See detailAffect et strategies d'approche/evitement
Grégoire, Christine; Dardenne, Benoît ULiege

in Revue Internationale de Psychologie Sociale = International Review of Social Psychology (2004), 17(1), 111-144

Après avoir présenté certaines conceptions de l'approche et de l'évitement en tant que régulateurs du comportement humain, nous défendons l'idée que les individus ressentant des affects positifs ... [more ▼]

Après avoir présenté certaines conceptions de l'approche et de l'évitement en tant que régulateurs du comportement humain, nous défendons l'idée que les individus ressentant des affects positifs développent une stratégie d'approche en situation sociale. Sur base de la théorie du «feeling-as-information» (Schwarz & Clore, 1988), l'affect peut être vu comme une information contextuelle sur l'environnement. L'information selon laquelle l'environnement ne pose pas de problème conduit les individus ressentant des affects positifs à adopter un comportement adapté vis-à-vis d'autrui et des situations sociales, alors que l'information selon laquelle l'environnement est menaçant conduit les individus ressentant des affects négatifs à davantage éviter autrui et les situations sociales. Nous illustrons notre propos par des recherches traitant de la quantité et de la qualité des activités sociales, ainsi que des comportements prosociaux. [less ▲]

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See detailHigh incidence of complications after 2-chloro-2'-deoxyadenosine combined with cyclophosphamide in patients with advanced lymphoproliferative malignancies.
Van Den Neste, E.; Michaux, L.; LAYIOS, Nathalie ULiege et al

in Annals of Hematology (2004), 83(6), 356-63

The combination of purine analogs with alkylating agents is able to produce a synergistic antitumoral effect. However, the addition of immunosuppressive and DNA-targeting agents might increase purine ... [more ▼]

The combination of purine analogs with alkylating agents is able to produce a synergistic antitumoral effect. However, the addition of immunosuppressive and DNA-targeting agents might increase purine analog-related complications. The risk for serious complications was evaluated in 38 patients treated with 2-chloro-2'-deoxyadenosine (CDA) and cyclophosphamide (CP). The diagnoses were chronic lymphocytic leukemia (CLL) in 15, Waldenstrom's macroglobulinemia in 4, mantle cell lymphoma in 6, follicular non-Hodgkin's lymphoma (NHL) in 10, and other low-grade NHL in 3 patients. All patients were pretreated (median: 2 lines, range: 1-5) and 23 (61%) were refractory. The patients received a median of two courses (range: 1-5) of 5.6 mg/m(2) CDA, followed by a median of 200 mg/m(2) CP, for 3 days. The response rate was 51% [complete remission (CR): 14%, partial remission (PR): 38%]. Grade 3/4 infections occurred in 16 (42%) patients. Dose-limiting cytopenias were seen in 22 (58%) patients. In 12 (32%) patients, autoimmune manifestations developed requiring treatment in most of them. Second cancers arose in five (13%) patients (myelodysplastic syndrome/acute myelocytic leukemia in three, lung cancer in two). Multivariate analysis showed that cytopenias, gender (F), prior radiotherapy, and age (>65 years) predicted for the complications seen after CDA-CP. To conclude, because of the high incidence of complications, caution is warranted in selecting patients with advanced lymphoid malignancies for the CDA-CP protocol. [less ▲]

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See detailApport de la papyrologie à l'histoire de la médecine
Marganne, Marie-Hélène ULiege

in Histoire des Sciences Médicales (2004), 38(2, Apr-Jun), 157-64

Two papyri are very interesting for Medicine history of the Antiquity. The first one (a Greek papyrus prolifically illustrated between 100 B.C. and 100 A.D.) reveals the value of the illustrators of works ... [more ▼]

Two papyri are very interesting for Medicine history of the Antiquity. The first one (a Greek papyrus prolifically illustrated between 100 B.C. and 100 A.D.) reveals the value of the illustrators of works in the Greek and Roman period and the second (the famous papyrus of Milan 300 B.C.) includes a part about the epigrams of curing. [less ▲]

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See detailA propos du deuil
Mormont, Christian ULiege

in Revue Francophone du Stress et du Trauma (2004), 4(4), 237-304

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See detailEcho du 9e colloque de l'AiRDF, Québec 26-28 aout 2004 : "Le français, discipline singulière, plurielle ou transversale ?"
Dumortier, Jean-Louis ULiege

in Enjeux : Revue de Formation Continuée et de Didactique du Français (2004), 60

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See detailReply to "Comment on 'Detuning effects in the one-photon mazer' "
Bastin, Thierry ULiege; Martin, John ULiege

in Physical Review. A (2004), 70

We refute in this Reply the criticisms made by Abdel-Aty. We show that none of them are founded and we demonstrate very explicitly what is wrong with the arguments developed by this author.

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See detailBall milling effect on the structure of single-wall carbon nanotubes
Pierard, N.; Fonseca, Antonio; Colomer, Jean-François et al

in Carbon (2004), 42(8-9), 1691-1697

The vibratory mill is used to decrease the single-wall carbon nanotubes (SWNTs) length and to increase their specific surface area. Electron microscopy, Raman spectroscopy, X-ray diffraction and BET ... [more ▼]

The vibratory mill is used to decrease the single-wall carbon nanotubes (SWNTs) length and to increase their specific surface area. Electron microscopy, Raman spectroscopy, X-ray diffraction and BET measurements indicated that the optimum time of treatment seems to be 2 h. After that, the SWNTs quality decreases, with a complete disruption of the tubular structure leading to multi-layered polyaromatic carbon materials observed after 50 h. (C) 2004 Elsevier Ltd. All rights reserved. [less ▲]

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See detailInhibitory Action Of A New Lectin From Xerocomus Chrysenteron On Cell-Substrate Adhesion
Marty-Detraves, C.; Francis, Frédéric ULiege; Baricault, L. et al

in Molecular and Cellular Biochemistry (2004), 258(1-2), 49-55

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See detailCatalogue des papyrus iatromagiques grecs
de Haro Sanchez, Magali ULiege

in Papyrologica Lupiensia (2004), 13

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See detailPrimary central nervous system lymphoma - Report of 32 cases and review of the literature
Dubuisson, Annie ULiege; Kaschten, Bruno ULiege; Lenelle, Jacques ULiege et al

in Clinical Neurology & Neurosurgery (2004), 107(1), 55-63

We retrospectively analyzed 32 cases of primary central nervous system lymphoma (PCNSL). Five cases were diagnosed in the period 1987-1994, for 27 cases in the period 1995-2002. There were 17 men and 15 ... [more ▼]

We retrospectively analyzed 32 cases of primary central nervous system lymphoma (PCNSL). Five cases were diagnosed in the period 1987-1994, for 27 cases in the period 1995-2002. There were 17 men and 15 women whose median age was 69 years. Three patients were immunodeficient. The commonest symptoms were focal deficit (16 patients) and cognitive/behaviour disturbances (14 patients). Radiologically, a total of 47 contrast-enhancing lesions were observed in 32 patients; 18 patients had deep-seated lesions. All but two patients underwent histological diagnosis following craniotomy (11 patients) and/or stereotaxic biopsy (22 patients); diagnosis was obtained on CSF cytology in one patient with a third ventricle tumour. In the last patient, the diagnosis was based on the finding of marked tumour shrinkage under corticotherapy, despite two negative histological examinations. Treatment included surgical resection (10 patients), chemotherapy (25 patients) and/or radiotherapy (12 patients). According to the therapeutic recommendations of the GELA (Groupe d'Etude des Lymphomes de l'Adulte), 19 patients received at least two courses of high-dose methotrexate; intrathecal chemotherapy was used in 20 patients with methotrexate and/or cytosine arabinoside. Radiation therapy consisted of whole brain irradiation followed by a boost on tumour site. Nine patients received a combined treatment of chemotherapy and radiotherapy. Twelve patients showed rapid progression to death. At the time of last contact, 28/32 patients (88%) had died, all from PCNSL disease or from complications due to its treatment. The median Survival time was 13.9 months. We conclude that PCNSL is an increasingly frequent tumour. The diagnosis is obtained by stereotactic biopsy in the majority of cases. The prognosis appears dismal despite an intensive multidisciplinary therapeutic approach. (C) 2004 Elsevier B.V. All rights reserved. [less ▲]

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See detailChromophoric dissolved organic matter in experimental mesocosms maintained under different pCO(2) levels
Rochelle-Newall, Emma; Delille, Bruno ULiege; Frankignoulle, Michel et al

in Marine Ecology. Progress Series (2004), 272

Chromophoric dissolved organic matter (CDOM) represents the optically active fraction of the bulk dissolved organic matter (DOM) pool. Recent evidence pointed towards a microbial source of CDOM in the ... [more ▼]

Chromophoric dissolved organic matter (CDOM) represents the optically active fraction of the bulk dissolved organic matter (DOM) pool. Recent evidence pointed towards a microbial source of CDOM in the aquatic environment and led to the proposal that phytoplankton is not a direct source of CDOM, but that heterotrophic bacteria, through reprocessing of DOM of algal origin, are an important source of CDOM. In a recent experiment designed at looking at the effects of elevated pCO(2) on blooms of the coccolithophorid alga Emiliania huxleyi, we found that despite the 3 different pCO(2) levels tested (190, 414 and 714 ppm), no differences were observed in accumulation of CDOM over the 20 d of incubation. Unlike previous mesocosm experiments where. relationships between CDOM accumulation and bacterial abundance have been observed, none was observed here. These results provide some new insights into the apparent lack of effect of pCO(2) on CDOM accumulation in surface waters, and question the previously proposed mechanisms and rates of CDOM production in natural phytoplankton blooms. [less ▲]

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See detailErgot poisoning in cattle
Brihoum, M.; Desmecht, Daniel ULiege; Bony, S. et al

in Annales de Médecine Vétérinaire (2004), 148(2), 97-101

In addition to the financial losses that ergot ( Claviceps purpurea) contamination causes in crops, the ingestion of ergot-contaminated food by cattle results in an intoxication that develops in several ... [more ▼]

In addition to the financial losses that ergot ( Claviceps purpurea) contamination causes in crops, the ingestion of ergot-contaminated food by cattle results in an intoxication that develops in several patterns. The observed clinical troubles may involve different systems. In this paper, we reviewed the clinical signs observed in ergot-poisoned cattle and some diagnostic and prevention aspects. [less ▲]

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See detailRésumé Cour d'appel de Bruxelles, 23 avril 2004
Delnoy, Michel ULiege

in Aménagement - Environnement (2004), 4

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See detailOrthophonie, le tremplin du passe, le dynamisme du present, l'essor du futur.
Estienne, Francoise; Morsomme, Dominique ULiege

in Presse Médicale (2004), 33 Spec No

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See detailLa route métastatique du mélanome.
Quatresooz, Pascale ULiege; Claessens, Nadine; Arrese Estrada, Jorge ULiege et al

in Skin (2004), 7

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See detailGenetic engineering of the β-oxidation pathway in the yeast Yarrowia lipolytica to increase the production of aroma compounds
Groguenin, A.; Waché, Y.; Garcia, E. E. et al

in Journal of Molecular Catalysis B : Enzymatic (2004), 28(2-3), 75-79

The yeast Yarrowia lipolytica possesses five acyl-CoA oxidases (Aox1p to 5), the enzyme catalysing the first reaction of β-oxidation. The understanding of the specific role of each acyl-CoA oxidase is ... [more ▼]

The yeast Yarrowia lipolytica possesses five acyl-CoA oxidases (Aox1p to 5), the enzyme catalysing the first reaction of β-oxidation. The understanding of the specific role of each acyl-CoA oxidase is important to construct a yeast strain growing at a good rate and able to produce without degrading the aroma compound γ-decalactone. In this study we observed that Aox4p exhibits a slight activity on a broad spectrum of substrates and that it is involved in lactone degradation. We constructed a strain lacking this activity. Its growth was only slightly altered and it produced 10 times more lactone than the wild type in 48h. © 2004 Elsevier B.V. All rights reserved. [less ▲]

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See detailHigh-Technology Service Innovation Success: A Decision-Making Perspective
Van Riel, Allard ULiege; Lemmink, Jos; Ouwersloot, Hans

in Journal of Product Innovation Management (2004), 21(5), 348-359

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See detailDetermination of the antimony valence state in Eu10Mn6Sb13
Brown, D. E.; Johnson, C. E.; Grandjean, Fernande ULiege et al

in Inorganic Chemistry (2004), 43(4), 1229-1234

The antimony-121 Mossbauer spectra of Eu10Mn6Sb13 have been measured between 2 and 295 K. Although the Zintl formalism indicates that the nine crystallographically distinct antimony sites in Eu10Mn6Sb13 ... [more ▼]

The antimony-121 Mossbauer spectra of Eu10Mn6Sb13 have been measured between 2 and 295 K. Although the Zintl formalism indicates that the nine crystallographically distinct antimony sites in Eu10Mn6Sb13 should have formal valence states of -2, -1, 0, and +1, the Mossbauer spectral isomer shifts reveal that the valence states of the 4.0 different sites are all quite similar and correspond to an average electronic configuration for antimony of 5s(1.7)5p(4.0). This configuration corresponds to an excess of negative charge on the antimony of 0.7 or an average valence of -0.7, a valence which is rather consistent with the average antimony valence of -0.61 obtained from the Zintl formalism for the nine antimony sites in Eu10Mn6Sb13. The spectra obtained between 90 and 295 K are more consistent with the absence rather than the presence of any transferred magnetic hyperfine field at the antimony. In contrast, the spectra obtained at 2 and 5 K reveal the presence of an average transferred magnetic hyperfine field of ca. 8 T, a field that arises from the ferromagnetic ordering of the near-neighbor manganese(II) ions. [less ▲]

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See detailComment amorcer la construction identitaire d'un praticien réflexif par la formation initiale ?
Beckers, Jacqueline ULiege

in Recherche et Formation (2004), 46

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