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See detailEmergency support of transmission voltages by active distribution networks: a non-intrusive scheme
Pabon Ospina, Luis David; Van Cutsem, Thierry ULiege

in IEEE Transactions on Power Systems (in press)

Non-negligible amounts of Distributed Generating Units (DGUs) are already connected to power systems, predominantly to medium- and low-voltage networks. The interaction between distribution and ... [more ▼]

Non-negligible amounts of Distributed Generating Units (DGUs) are already connected to power systems, predominantly to medium- and low-voltage networks. The interaction between distribution and transmission systems is gaining the attention of system operators. Given the high controlability of DGUs, the active distribution networks can potentially support the transmission system during emergency situations. Previously proposed voltage emergency controls involving distribution network assets focused on preserving the transmission system integrity, even if it implies affecting the distribution system operation (intrusive schemes). More attention needs to be devoted to supporting transmission voltages, while preserving the distribution network operation (non-intrusive schemes). This paper introduces a new adaptive and non-intrusive voltage emergency control scheme based on the synchronization of DGUs and the load tap changer of the corresponding distribution transformer. The conclusions are derived from time-domain simulations using an extended version of the IEEE Nordic test system for voltage stability assessment. [less ▲]

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See detailContact Pressure Between the Vocal Folds in Reinke’s Edema: Experimental Observations on an Excised Human Larynx
SILVA, FABRICE; LEGOU, THIERRY; CHAMPSAUR, PIERRE et al

in Journal of Voice (in press)

Objective. To analyze the range of values of the contact pressure between the membranous vocal folds with Reinke’s edema and to compare it to those observed in the absence of such a lesion. Methods. Two ... [more ▼]

Objective. To analyze the range of values of the contact pressure between the membranous vocal folds with Reinke’s edema and to compare it to those observed in the absence of such a lesion. Methods. Two human larynges were separately tested on the experimental bench, one of them with a bilateral loose swelling of the vocal folds. Once in a glottal prephonatory configuration, airflow was increased until achievement of self-sustained oscillations while recording aerodynamic, acoustic, electroglottographic data, and contact pressure between the folds. Results. We observed well-documented variations in acoustical parameters, as the decrease of the fundamental frequency and the increase of the phonation threshold pressure. The results of the study also point to a significant increase in the amplitude of the contact pressure in presence of the Reinke’s edema, and a lower degree of harmonicity of the produced sounds. Conclusion. This is the first report of ex vivo study of a larynx with Reinke’s edema. It highlights the increase in the contact pressure during phonation, which possibly contributes to sustain the lesion once it appeared. [less ▲]

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See detailUn regard post-coloniliste de la médiatisation européenne à l'heure des Femen en Tunisie
Luceno Moreno, Marta ULiege

in Open Library of Humanities (in press)

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See detailProtecting olympic participants from COVID-19: the trialled and tested process.
Pigozzi, Fabio; Wolfarth, Bernd; Cintron Rodriguez, Ana et al

in British journal of sports medicine (in press)

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See detailStatistics and linguistics: can we tell something more about Pliny the Elder?
Fantoli, Margherita ULiege

in Classics@ (in press)

Présentation des outils et des méthodes L.A.S.L.A. et discussion des premiers résultats des tests statistiques sur le deuxième livre de la Naturalis Historia de Pline l'Ancien.

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See detailPratiques éducatives parentales et premières compétences en numératie des enfants d’âge préscolaire selon le niveau socio-économique et culturel des familles
Poncelet, Débora; de Chambrier, Anne-Françoise; Tinnes-Vigne, Mélanie et al

in Revue Internationale de l'Education Familiale (in press)

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See detailAgeism among psychology students: A comparative analysis between Belgium and Quebec (Canada)
Marquet, Manon ULiege; Vallet, Guillaume; Adam, Stéphane ULiege et al

in Année Psychologique (in press)

This study aimed to examine ageist attitudes in psychology students who may become the healthcare professionals. We also compared cultural differences between attitudes in Belgium and Quebec. We ... [more ▼]

This study aimed to examine ageist attitudes in psychology students who may become the healthcare professionals. We also compared cultural differences between attitudes in Belgium and Quebec. We hypothesized that psychology students would have more positive attitudes toward older people in Quebec than in Belgium. Quebec has indeed more invested in age-friendly initiatives that may promote socio-economic factors associated with better attitudes toward older people. A total of 236 psychology students participated in this study (81 Belgian students and 155 Quebec students). The students completed different self-reported questionnaires to assess their attitudes toward older people. As predicted, the results showed that students in Quebec were overall less negative toward older adults. Since negative attitudes may influence students’ choice to work with older people and may also have damaging consequences in the assessment and/or healing context, we discuss different directions to improve these attitudes. [less ▲]

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See detailVitamin D Standardization Program (VDSP) Intralaboratory Study for the Assessment of 25-Hydroxyvitamin D Assay Variability and Bias.
Wise, Stephen A.; Camara, Johanna E.; Sempos, Christopher T. et al

in The Journal of steroid biochemistry and molecular biology (in press)

An intralaboratory study assessing assay variability and bias for determination of serum total 25-hydroxyvitamin D [25(OH)D] was conducted by the Vitamin D Standardization Program (VDSP). Thirteen assays ... [more ▼]

An intralaboratory study assessing assay variability and bias for determination of serum total 25-hydroxyvitamin D [25(OH)D] was conducted by the Vitamin D Standardization Program (VDSP). Thirteen assays for serum total 25(OH)D were evaluated in a single laboratory including 11 unique immunoassays and one liquid chromatography - tandem mass spectrometry (LC-MS/MS) assay. Fifty single-donor serum samples, including eight samples with high concentrations of 25(OH)D(2) (> 30 nmol/L), were assigned target values for 25(OH)D(2) and 25(OH)D(3) using reference measurement procedures (RMP). Using four replicate measurements for each sample, the mean total percent coefficient of variation (%CV) and mean % bias from the target values were determined for each assay using the 50 single-donor samples and a 42-sample subset, which excluded 8 high 25(OH)D(2) concentration samples, and compared with VDSP performance criteria of ≤ 10% CV and ≤ ±5% mean bias. All 12 assays achieved the performance criterion for %CV, and 9 of the 12 assays were within ≤ ±5 % mean bias. The Fujirebio Inc. assay exhibited the lowest %CV and highest percentage of individual measurements within ≤ ±5% mean bias. Ten immunoassays exhibited changes in response due to the high 25(OH)D(2) samples with Abbott, Biomérieux, DiaSorin, DIAsource, and IDS-iSYS assays having the largest deviations. The Fujirebio Inc. and Beckman Coulter assays were only minimally affected by the presence of the high 25(OH)D(2) samples. Samples with high concentrations of 25(OH)D(2) provided a critical performance test for immunoassays indicating that some assays may not have equal response or recovery for 25(OH)D(2) and 25(OH)D(3). [less ▲]

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See detailDécrire n’est pas tout: Kurt Lewin sur l’émotion
Seron, Denis ULiege

in Philosophie (in press)

La présente contribution discute quelques aspects de la psychologie affective de Lewin et de ses continuateurs. La thèse centrale sous-jacente à celle-ci se ramène à la formule suivante, due à Koffka : « ... [more ▼]

La présente contribution discute quelques aspects de la psychologie affective de Lewin et de ses continuateurs. La thèse centrale sous-jacente à celle-ci se ramène à la formule suivante, due à Koffka : « Le problème de l’émotion n’est pas un problème de classification et d’analyse introspective, mais un problème de dynamique et d’analyse fonctionnelle . » Le but de cet article est de clarifier et de discuter le sens de cette thèse. [less ▲]

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See detailStratigrapheR: Concepts for Litholog Generation in R
Wouters, Sébastien ULiege; Da Silva, Anne-Christine ULiege; Boulvain, Frédéric ULiege et al

in The R Journal (in press)

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See detailOdanacatib for the treatment of postmenopausal osteoporosis: results of the LOFT multicenter, randomized, double-blind, placebo-controlled trial and LOFT Extension Study
McClung, M.R.; O'Donoghue, M.L.; Papapoulos, S.E. et al

in Lancet Diabetes and Endocrinology (in press)

Background: Odanacatib, a cathepsin K inhibitor, reduces bone resorption while maintaining bone formation. Previous work has shown that odanacatib increases bone mineral density in postmenopausal women ... [more ▼]

Background: Odanacatib, a cathepsin K inhibitor, reduces bone resorption while maintaining bone formation. Previous work has shown that odanacatib increases bone mineral density in postmenopausal women with low bone mass. We aimed to investigate the efficacy and safety of odanacatib to reduce fracture risk in postmenopausal women with osteoporosis. Methods: The Long-term Odanacatib Fracture Trial (LOFT) was a multicentre, randomised, double-blind, placebocontrolled, event-driven study at 388 outpatient clinics in 40 countries. Eligible participants were women aged at least 65 years who were postmenopausal for 5 years or more, with a femoral neck or total hip bone mineral density T-score between –2·5 and –4·0 if no previous radiographic vertebral fracture, or between –1·5 and –4·0 with a previous vertebral fracture. Women with a previous hip fracture, more than one vertebral fracture, or a T-score of less than –4·0 at the total hip or femoral neck were not eligible unless they were unable or unwilling to use approved osteoporosis treatment. Participants were randomly assigned (1:1) to either oral odanacatib (50 mg once per week) or matching placebo. Randomisation was done using an interactive voice recognition system after stratification for previous radiographic vertebral fracture, and treatment was masked to study participants, investigators and their staff, and sponsor personnel. If the study completed before 5 years of double-blind treatment, consenting participants could enrol in a double-blind extension study (LOFT Extension), continuing their original treatment assignment for up to 5 years from randomisation. Primary endpoints were incidence of vertebral fractures as assessed using radiographs collected at baseline, 6 and 12 months, yearly, and at final study visit in participants for whom evaluable radiograph images were available at baseline and at least one other timepoint, and hip and non-vertebral fractures adjudicated as being a result of osteoporosis as assessed by clinical history and radiograph. Safety was assessed in participants who received at least one dose of study drug. The adjudicated cardiovascular safety endpoints were a composite of cardiovascular death, myocardial infarction, or stroke, and new-onset atrial fibrillation or flutter. Individual cardiovascular endpoints and death were also assessed. LOFT and LOFT Extension are registered with ClinicalTrials.gov (number NCT00529373) and the European Clinical Trials Database (EudraCT number 2007-002693-66). Findings: Between Sept 14, 2007, and Nov 17, 2009, we randomly assigned 16 071 evaluable patients to treatment: 8043 to odanacatib and 8028 to placebo. After a median follow-up of 36·5 months (IQR 34·43–40·15) 4297 women assigned to odanacatib and 3960 assigned to placebo enrolled in LOFT Extension (total median follow-up 47·6 months, IQR 35·45–60·06). In LOFT, cumulative incidence of primary outcomes for odanacatib versus placebo were: radiographic vertebral fractures 3·7% (251/6770) versus 7·8% (542/6910), hazard ratio (HR) 0·46, 95% CI 0·40–0·53; hip fractures 0·8% (65/8043) versus 1·6% (125/8028), 0·53, 0·39–0·71; non-vertebral fractures 5·1% (412/8043) versus 6·7% (541/8028), 0·77, 0·68–0·87; all p<0·0001. Combined results from LOFT plus LOFT Extension for cumulative incidence of primary outcomes for odanacatib versus placebo were: radiographic vertebral fractures 4·9% (341/6909) versus 9·6% (675/7011), HR 0·48, 95% CI 0·42–0·55; hip fractures 1·1% (86/8043) versus 2·0% (162/8028), 0·52, 0·40–0·67; non-vertebral fractures 6·4% (512/8043) versus 8·4% (675/8028), 0·74, 0·66–0·83; all p<0·0001. In LOFT, the composite cardiovascular endpoint of cardiovascular death, myocardial infarction, or stroke occurred in 273 (3·4%) of 8043 patients in the odanacatib group versus 245 (3·1%) of 8028 in the placebo group (HR 1·12, 95% CI 0·95–1·34; p=0·18). New-onset atrial fibrillation or flutter occurred in 112 (1·4%) of 8043 patients in the odanacatib group versus 96 (1·2%) of 8028 in the placebo group (HR 1·18, 0·90–1·55; p=0·24). Odanacatib was associated with an increased risk of stroke (1·7% [136/8043] vs 1·3% [104/8028], HR 1·32, 1·02–1·70; p=0·034), but not myocardial infarction (0·7% [60/8043] vs 0·9% [74/8028], HR 0·82, 0·58–1·15; p=0·26). The HR for all-cause mortality was 1·13 (5·0% [401/8043] vs 4·4% [356/8028], 0·98–1·30; p=0·10).When data from LOFT Extension were included, the composite of cardiovascular death, myocardial infarction, or stroke occurred in significantly more patients in the odanacatib group than in the placebo group (401 [5·0%] of 8043 vs 343 [4·3%] of 8028, HR 1·17, 1·02–1·36; p=0·029, as did stroke (2·3% [187/8043] vs 1·7% [137/8028], HR 1·37, 1·10–1·71; p=0·0051). Interpretation: Odanacatib reduced the risk of fracture, but was associated with an increased risk of cardiovascular events, specifically stroke, in postmenopausal women with osteoporosis. Based on the overall balance between benefit and risk, the study’s sponsor decided that they would no longer pursue development of odanacatib for treatment of osteoporosis. [less ▲]

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See detailQuand le Conseil d'État pratique l'Art poétique
Grandjean, Geoffrey ULiege

in Administration Publique: Revue du Droit Public et des Sciences Administratives (in press), 1

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See detailResponsabilité pénale des personnes morales
Jacobs, Ann ULiege; Dister, Jean-François; Thevissen, Patrick ULiege et al

in Postal Memorialis (in press)

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See detailInundation, hydrodynamics, and vegetation influences carbon dioxide concentrations in Amazon floodplain lakes
Amaral, João Henrique Fernandes; Melack, John Michael; Barbosa, Pedro Maia et al

in Biogeochemistry (in press)

Extensive floodplains and numerous lakes in the Amazon basin are well suited to examine the role of floodable lands within the context of the sources and processing of carbon within inland waters. We ... [more ▼]

Extensive floodplains and numerous lakes in the Amazon basin are well suited to examine the role of floodable lands within the context of the sources and processing of carbon within inland waters. We measured diel, seasonal and inter-annual variations of carbon dioxide concentrations and related environmental variables in open water and flooded vegetation and estimated the area of these habitats using remote sensing in a representative central Amazon floodplain lake, Lake Janauacá. Depth-averaged values of CO2 in the open water of the lake, 157 ± 91 µM (mean ± SD), were less than those in an embayment near aquatic vegetation, 285 ± 116 µM, and were variable over 24-h periods at both sites. Within floating herbaceous plant mats, the mean concentration was 275 ± 77 µM and in flooded forests the mean concentration was 217 ± 78 µM. Variability in CO2 concentrations in open water resulted from changes in the extent of inundation and exchange with vegetated habitats. The best statistical model, that included CO2 in aquatic plant mats, Secchi depth, rate of change in water level and chlorophyll concentrations, explained around 90% of the variability in CO2 concentration. Three-dimensional hydrodynamic modeling demonstrated that diel differences in water temperature between plant mats and open water as well as basin-scale motions caused lateral exchanges of CO2 linking vegetated habitats to open water. Our findings extend understanding of CO2 in tropical lakes and floodplains with measurements and models that emphasize the importance of flooded forests and aquatic herbaceous plants fringing floodplain lakes as sources of carbon dioxide to the open waters. [less ▲]

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See detailPotential for the use of lactoperoxidase against post-harvest diseases on fruit
Bafort, Françoise ULiege; Perraudin, Jean-Paul; Jijakli, Haissam ULiege

in Acta Horticulturae (in press)

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See detailCancer immunotherapy: it’s time to better predict patients’ response
Pilard, Charlotte ULiege; Ancion, Marie ULiege; Delvenne, Philippe ULiege et al

in British Journal of Cancer (in press)

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See detailLa question de l’éducation : aiguillon des philosophies politiques. Castoriadis/Rancière.
Wustefeld, Sophie ULiege

in MethIS: Méthodes et Interdisciplinarité en Sciences Humaines (in press)

La démocratie reste un thème chéri par la philosophie politique contemporaine, pour l’écart entre ses théories et ses pratiques, pour la distance critique que ses théories offrent vis-à-vis des régimes ... [more ▼]

La démocratie reste un thème chéri par la philosophie politique contemporaine, pour l’écart entre ses théories et ses pratiques, pour la distance critique que ses théories offrent vis-à-vis des régimes démocratiques et de leur évolution, mais aussi parce qu’elle est un objet perpétuel de dissensus entre philosophes, au sujet duquel toute prétention à la véridiction est suspendue à sa réalisation pratique. À ce titre, la transmission de la volonté démocratique est un topos houleux de la philosophie politique contemporaine. Cette question catalyse les concepts pivots des philosophies politiques, la leur poser permet de mieux saisir les enjeux rivaux derrière une terminologie commune à plusieurs auteurs. C’est dans cette démarche que je vous propose d’examiner en miroir les philosophies de Cornélius Castoriadis et de Jacques Rancière. De plus en plus nombreux, des commentateurs rapprochent leurs pensées , qui peuvent s’appuyer sur plusieurs points communs : un attachement au concept de démocratie brandit contre les régimes parlementaires, une opposition contemporaine (quoique depuis des héritages différents) aux thèses défendues par Althusser, et une proximité de sources d’inspirations : la philosophie, le marxisme, et la psychanalyse. Partant de la manière dont cette proximité s’exprime dans la disjonction que chacun opère entre démocratie et science, je tenterai de discerner comment les inflexions qu’ils impriment aux concepts de volonté et d’égalité sous la guise des enjeux de la transmission dessinent des horizons politiques distincts, et dénotent des compréhensions antithétiques – mais indécidables dans la théorie – de ce que peut être la démocratie. [less ▲]

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See detailReducibility of n-ary semigroups: from quasitriviality towards idempotency
Couceiro, Miguel; Devillet, Jimmy; Marichal, Jean-Luc et al

in Beiträge zur Algebra und Geometrie (in press)

Let $X$ be a nonempty set. Denote by $\mathcal{F}^n_k$ the class of associative operations $F\colon X^n\to X$ satisfying the condition $F(x_1,\ldots,x_n)\in\{x_1,\ldots,x_n\}$ whenever at least $k$ of the ... [more ▼]

Let $X$ be a nonempty set. Denote by $\mathcal{F}^n_k$ the class of associative operations $F\colon X^n\to X$ satisfying the condition $F(x_1,\ldots,x_n)\in\{x_1,\ldots,x_n\}$ whenever at least $k$ of the elements $x_1,\ldots,x_n$ are equal to each other. The elements of $\mathcal{F}^n_1$ are said to be quasitrivial and those of $\mathcal{F}^n_n$ are said to be idempotent. We show that $\mathcal{F}^n_1=\cdots =\mathcal{F}^n_{n-2}\subseteq\mathcal{F}^n_{n-1}\subseteq\mathcal{F}^n_n$ and we give conditions on the set $X$ for the last inclusions to be strict. The class $\mathcal{F}^n_1$ was recently characterized by Couceiro and Devillet \cite{CouDev}, who showed that its elements are reducible to binary associative operations. However, some elements of $\mathcal{F}^n_n$ are not reducible. In this paper, we characterize the class $\mathcal{F}^n_{n-1}\setminus\mathcal{F}^n_1$ and show that its elements are reducible. We give a full description of the corresponding reductions and show how each of them is built from a quasitrivial semigroup and an Abelian group whose exponent divides $n-1$. [less ▲]

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See detailIntégrer le droit international au champ des relations internationales : les juristes belges à Versailles en 1919
Genin, Vincent ULiege

in Relations internationales (in press), (2),

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See detailEffect of cyclo-oxygenase inhibition on embryonic microglia and the sexual differentiation of the brain and behavior of Japanese quail (Coturnix japonica)
Delage, Charlotte ULiege; Nys, Gwenaël ULiege; Fillet, Marianne ULiege et al

in Hormones and Behavior (in press)

Enduring sex differences in the brain are established during a developmental process known as brain sexual differentiation and are mainly driven by estrogens during a critical period. In rodents, the ... [more ▼]

Enduring sex differences in the brain are established during a developmental process known as brain sexual differentiation and are mainly driven by estrogens during a critical period. In rodents, the masculinization of the preoptic area by estrogens derived from the central aromatization of testosterone depends in part on the interaction between microglia and prostaglandin E2 (PGE2), a pro-inflammatory hormone of the prostanoid subclass. In contrast, in birds, estrogens produced by females induce a demasculinization, but whether an interaction with the neuro-immune system is involved in this process is unknown. This study addressed this question by testing the effects of blockade of cyclo-oxygenases (COX), the rate-limiting enzymes for prostanoid synthesis, on embryonic microglia and the sexual differentiation of brain and behavior using the Japanese quail as an animal model. The results show that COX inhibition does not affect the behavior of females, but impairs male sexual behavior and suppresses the sex difference in microglial profiles at embryonic day 12 (E12) in the medial preoptic nucleus by increasing the number of microglia in males only. However, neither prostanoid concentrations nor PGE2 receptors differed between sexes in the hypothalamus and preoptic area (HPOA) during development. Overall, these results uncovered a potential role of prostanoids in the demasculinization of Japanese quail. Moreover, the parallel effect of COX inhibition on behavior and microglia suggests an interaction between prostanoids and microglia in brain demasculinization, thus fueling the hypothesis of a conserved role of the neuroimmune system in the organization of the brain by estrogens. [less ▲]

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See detail2021 revised algorithm for the management of knee osteoarthritis-the Chinese viewpoint.
Zhang, Zhiyi; Huang, Cibo; Cao, Yongping et al

in Aging clinical and experimental research (in press)

AIM: The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) algorithm for the management of knee osteoarthritis (OA) is available ... [more ▼]

AIM: The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) algorithm for the management of knee osteoarthritis (OA) is available worldwide from 2014, but in 2019 an update was published. Based on this algorithm, a Working Group (WG), including ESCEO members and Chinese experts, wished to see how the new ESCEO algorithm was perceived by Chinese experts in knee OA and how it was integrated into their clinical practice. METHODS: A WG was held between members of the international ESCEO task force and a group of Chinese experts. RESULTS: Non-pharmacological approach should be combined with pharmacological interventions. In step 1, symptomatic slow-acting drugs for osteoarthritis (SYSADOA) are the most important background drugs. Evidence, supported by high-quality research, is available only for crystalline glucosamine sulfate (pCGS) and chondroitin sulfate. Topical NSAIDs could be used as an additional option. In step 2, oral NSAIDs could be useful, but cardiovascular/renal/gastrointestinal profiles of the patients should be considered. Intra-articular hyaluronic acid and corticosteroids are alternative to oral NSAIDs, but the evidence is still limited. If steps 1 and 2 are not sufficient, weak opioids could be used. Overall, the conclusions of the ESCEO algorithm are accepted in China for products available in this country. The WG suggests the importance of economic studies, specifically made in China. CONCLUSION: This work provides evidence-based advice to establish a treatment algorithm in knee OA, for practical implementation in clinical practice in China. [less ▲]

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See detailPolyhydroxybenzoic acid derivatives as potential new antimalarial agents
Degotte, Gilles ULiege; Pirotte, Bernard ULiege; Frederich, Michel ULiege et al

in Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft (in press)

With more than 200 million cases and 400,000 related deaths, malaria remains one of the deadliest infectious diseases of 2021. Unfortunately, despite the availability of efficient treatments, we have ... [more ▼]

With more than 200 million cases and 400,000 related deaths, malaria remains one of the deadliest infectious diseases of 2021. Unfortunately, despite the availability of efficient treatments, we have observed an increase in people infected with malaria since 2015 (from 211 million in 2015 to 229 million in 2019). This trend could partially be due to the development of resistance to all the current drugs. Therefore, there is an urgent need for new alternatives. We have, thus, selected common natural scaffolds, polyhydroxybenzoic acids, and synthesized a library of derivatives to better under- stand the structure–activity relationships explaining their antiplasmodial effect. Only gallic acid derivatives showed a noticeable potential for furtherQ3 developments. Indeed, they showed a selective inhibitory effect on Plasmodium (IC50 ~20 μM, SI > 5) often associated with interesting water solubility. Moreover, this has confirmed the critical importance of free phenolic functions (pyrogallol moiety) for the antimalarial effect. Methyl 4-benzoxy-3,5-dihydroxybenzoate (39) has, for the first time, been recognized as a potential lead for future research because of its marked inhibitory activity against Plasmodium falciparum and its significant hydrosolubility (3.72 mM). [less ▲]

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See detailL’intreccio del Tristan en prose e altri appunti
Morato, Nicola ULiege

in Stilistica e Metrica Italiana (in press)

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See detail"Cooperative game” inspired approach for multi-area power system: day ahead – intraday markets & security management taking advantage of grid flexibilities
Karangelos, Efthymios ULiege; Panciatici, Patrick

in Philosophical Transactions of the Royal Society of London. Series A, Containing Papers of a Mathematical or Physical Character (in press)

This paper advocates for a progressive rethinking of the day-ahead/intra-day power system security management practice in the low-carbon energy transition era. As a starting point, the need for multi-TSO ... [more ▼]

This paper advocates for a progressive rethinking of the day-ahead/intra-day power system security management practice in the low-carbon energy transition era. As a starting point, the need for multi-TSO coordination in order to efficiently exploit the value of grid flexibility towards operating the low-carbon, multi-area power system securely and economically is established. On this basis, the core proposal of this paper is the adoption of a new approach to day-ahead/intra-day multi-area power system security management, inspired from the principles of cooperative game theory. The proposed approach relies on counterfactual analysis to evaluate the (positive and/or negative) impact of each distinctive control-area to the common security of the multi-area system, thus providing clear economic incentives to achieve the required coordination. This proposal is not a marginal approach and notably facilitates the integration of more detailed physical modeling (including the non-convexities of the power system) in the inter-TSO settlement of the multi-area interconnected system security management cost. The proposed framework allows some level of subsidiarity and the definition of hedging products to cover ex-post costs. Further from the blueprint of the proposed approach, the paper discusses prominent research and development pathways in order to progressively put such vision into practice. [less ▲]

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See detailL’œil du cycle. Réseaux textuels et stemmata codicum dans la tradition des textes arthuriens
Morato, Nicola ULiege

in Encomia : Bulletin Bibliographique de la Société Internationale de Littérature Courtoise (in press)

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See detailProf en République Démocratique du Congo : un métier de femmes ?
Kitenge Maningo, Sara ULiege

in Le (in press)

L’égalité des sexes est un droit pour tous, et sa réalisation n’est pas uniquement bénéfique aux femmes, mais pour tous. Particulièrement au niveau de la recherche et de l’enseignement supérieur, on a ... [more ▼]

L’égalité des sexes est un droit pour tous, et sa réalisation n’est pas uniquement bénéfique aux femmes, mais pour tous. Particulièrement au niveau de la recherche et de l’enseignement supérieur, on a tout intérêt à exploiter l’ensemble du potentiel humain, à mobiliser tous les talents. Exclure les femmes, c’est en effet gaspiller des compétences ! Petit tour d’horizon de la situation académique en RDC, et piste de solutions. [less ▲]

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See detailBrentano and the ideality of time
Seron, Denis ULiege

in Revista de Filosofia Moderna e Contemporânea (in press), 9(2),

How is it possible to have present memory experiences of things that, being past, are no longer presently experienced? A possible answer to this long-standing philosophical question is what I call the ... [more ▼]

How is it possible to have present memory experiences of things that, being past, are no longer presently experienced? A possible answer to this long-standing philosophical question is what I call the “ideality of time view,” namely the view that temporal succession is unreal. In this paper I outline the basic idea behind Brentano’s version of the ideality of time view. Additionally, I contrast it with Hume’s version, suggesting that, despite significant differences, it can nonetheless be construed as broadly Humean. [less ▲]

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See detailInvestigating densities of Symbiodiniaceae in two species of Antipatharians (black corals) from Madagascar
Gress, Erika; Eeckhaut, Igor; Godefroid, Mathilde et al

in Oceans (in press)

Here, we report the first methodological approach to investigate the presence and estimate density of Symbiodiniaceae cells in corals of the order Antipatharia subclass Hexacorallia, known as black corals ... [more ▼]

Here, we report the first methodological approach to investigate the presence and estimate density of Symbiodiniaceae cells in corals of the order Antipatharia subclass Hexacorallia, known as black corals. Antipatharians are understudied ecosystem engineers of shallow (<30 m depth), mesophotic (30-150 m) and deep-sea (>200 m) reefs. They provide habitat to a vast number of marine fauna, enhancing and supporting coral reefs biodiversity globally. Nonetheless, little biological and ecological information exists on antipatharians, including the extent at which global change disturbances are threatening these corals. The assumption that they were exempted from threats related to climate change was challenged by findings of high density of dinoflagellates within three antipatharian colonies. Further methodical studies were necessary to investigate the regularity of these findings. An integrated design combining microscopy and molecular techniques was used to investigate the presence and estimate density of Symbiodiniaceae cells within two antipatharians species - Cupressopathes abies and Stichopathes maldivensis - from shallow and mesophotic reefs of SW Madagascar. Symbiodiniaceae-like cells were found within the two species from both shallow and mesophotic reefs, although the overall cell density was very low (0-4 cell mm-3). These findings suggest that high abundance of Symbiodiniaceae is not characteristic of antipatharians, which has relevant implications considering climate change associated disruptions in other corals. However, the high densities of dinoflagellates found in antipatharian colonies exposed to higher light irradiance in other studies should be further examined. [less ▲]

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See detailMinimal requirements for the vibration-based identification of the axial force, the bending stiffness and the flexural boundary conditions in cables
Geuzaine, Margaux ULiege; Foti, Francesco; Denoël, Vincent ULiege

in Journal of Sound and Vibration (in press)

This paper aims at presenting the guidelines to follow in order to set up an identification procedure which is able to determine the axial force, the flexural rigidity and the rotational end stiffnesses ... [more ▼]

This paper aims at presenting the guidelines to follow in order to set up an identification procedure which is able to determine the axial force, the flexural rigidity and the rotational end stiffnesses of slender and tensioned structural elements, based on measurements of their natural frequencies and mode shapes. First of all, when such an element is slightly affected by bending stiffness effects, perturbation methods can be applied to get a composite approximation for its natural frequencies and an asymptotic expression for its mode shapes. These simple analytical formulas allow to understand the role played by each model parameter in the modal response and show that the axial force, the flexural rigidity and the rotational end stiffnesses can be correctly identified under some conditions, which are established and provided in this document. Among others, it is necessary that the identification procedure relies on the first few natural frequencies and mode shapes, which are measured near each extremity of the element, as well as some natural frequencies associated with higher modes. [less ▲]

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See detailLes pathologies de la liberté (ou la liberté des pathologies) : La ballade de Germain
Englebert, Jérôme ULiege

in Klēsis: Revue Philosophique (in press)

Mon objectif est de soumettre le concept de « pathologies de la liberté » à triple épreuve. 1/ à travers le célèbre conflit historique de la psychiatrie française opposant Henri Ey à Jacques Lacan sur la ... [more ▼]

Mon objectif est de soumettre le concept de « pathologies de la liberté » à triple épreuve. 1/ à travers le célèbre conflit historique de la psychiatrie française opposant Henri Ey à Jacques Lacan sur la présence de la liberté au sein de la maladie mentale ; 2/ à travers l’opposition que nous identifierons entre les méthodes prônées par Binswanger et par Minkowski pour réaliser une compréhension psychopathologique de l’individu ; 3/ à travers la clinique, le cas Germain, patient psychotique dont nous reprendrons l’histoire qui le verra s’opposer au monde entier. Je donnerai différents arguments en analysant ces débats (historiques, méthodologiques et cliniques) afin de proposer une lecture singulière des pathologies de la liberté et de voir comment cette lecture s’inscrit dans le champ psychopathologique. L’objectif de ma contribution sera de rencontrer le vécu en première personne du sujet psychotique qui se retrouve mal dans la qualification de son existence comme étant privée de liberté. Comme le titre de cette étude l’annonce, la thèse que je défends est de considérer que l’interrogation des pathologies de la liberté conduit également à interroger son corollaire, la dimension inéluctablement libre inhérente aux personnes affectées de psychopathologies. Ce décalage, que nous permettra d’entrevoir Lacan, nous mènera à interroger la dimension adaptative de l’expérience psychopathologique et, dans la continuité de Canguilhem, à considérer la pathologie comme la création de normes inédites (généralement inaccessibles à autrui). [less ▲]

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See detailPRISE EN CHARGE CHIRURGICALE DE LA MALADIE D’OTTO CHEZ L’ENFANT
Kabore, Christophe ULiege; Allington, Nanni ULiege

in Ortho-Rhumato (in press)

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See detailVous avez dit..."Réforme de la formation initiale des enseignants"?
Hindryckx, Marie-Noëlle ULiege; Sottiaux, Etienne

in Didactiques en Pratique (in press), 6

Le dossier RFIE est un dossier à rebondissements. Néanmoins, le dialogue au sein du Pole Académique Liège Luxembourg est effectif et permet d'envisager une réelle collaboration entre ces institutions de ... [more ▼]

Le dossier RFIE est un dossier à rebondissements. Néanmoins, le dialogue au sein du Pole Académique Liège Luxembourg est effectif et permet d'envisager une réelle collaboration entre ces institutions de formation des enseignants. Cet article se veut une photographie à l'instant "t" de cette réforme et des décrets y attenant. [less ▲]

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See detailLes critiques chrétiennes des lectisternes et sellisternes romains : un banquet trop anthropomorphe ?
Berthelet, Yann ULiege

in Les Cahiers du CEDOPAL (in press)

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See detailPsychopathologie et monde social : les limites de l'empathie et de la sympathie
Englebert, Jérôme ULiege

in Philosophie (in press)

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See detailCan ambulatory biofeedback help a transgender woman speak at a higher pitch?
Morsomme, Dominique ULiege; Remacle, Angélique ULiege

in Logopedics, Phoniatrics, Vocology (in press)

Voice feminization for transgender women remains a challenge. The fundamental frequency of the voice (fo) is one of the main parameters contributing to the perception of gender. One of the aims of voice ... [more ▼]

Voice feminization for transgender women remains a challenge. The fundamental frequency of the voice (fo) is one of the main parameters contributing to the perception of gender. One of the aims of voice therapy is to help transgender women acquire a new vocal motor behavior to increase their fo. We hypothesized that ambulatory biofeedback could help extend the new vocal behavior to daily life. This prospective case study assessed the impact of two weeks of ambulatory vibrotactile biofeedback (VTBF) applied to one transgender woman, following two weeks of voice therapy (three 60-minute sessions). The VTBF was activated when the participant’s voice was lower than 150 Hz for more than 500 ms and was accompanied by two 60-minute counseling sessions. The results showed that mean fo monitored in daily activities tended to increase following the two weeks of voice therapy (Δ = 8 Hz or 1 semitone) and then increased significantly immediately after the two weeks of VTBF (Δ = 13 Hz or 1.5 semitones). The increase in mean fo from day to day and the decrease in the activation percentage from the first to the second week of VTBF (Δ = 6%) indicated a gradual integration of the motor behavior, making it possible to achieve the targeted female frequency. The results suggest that ambulatory VTBF helped the participant to generalize the techniques acquired during the voice therapy sessions to real-life communication situations. These results are promising for therapeutic programs that integrate tools that can be used outside the clinical context. [less ▲]

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See detailAn individualised approach for a one-abutment one-time protocol using full guided surgery: a 4-year follow-up case series
VINCENT, Kim ULiege; LI MANNI, Lou; Mainjot, Amélie ULiege et al

in International Journal of Computerized Dentistry (in press)

Aim: The aim of this case series was to evaluate the 4-year outcomes of implants placed in the aesthetic area using static computer-assisted implant surgery (s-CAIS) and restored with a one-abutment one ... [more ▼]

Aim: The aim of this case series was to evaluate the 4-year outcomes of implants placed in the aesthetic area using static computer-assisted implant surgery (s-CAIS) and restored with a one-abutment one-time (OAOT) protocol using custom-made zirconia abutments and cemented provisional crowns manufactured prior to surgery. Material and methods: Ten consecutive implants were placed in the aesthetic area. Based on a digital implant and prosthodontic planning, surgical guides were ordered and used for the preparation of definitive custom-made zirconia abutments and polymethylmethacrylate provisional crowns. Implants were placed using the s-CAIS guide, and prosthetic components were placed immediately. Implant outcomes were evaluated at the time of surgery, after 4 months and after 4 years. Results: All implants were successfully placed with s-CAIS and restored with final abutments and provisional crowns. No major prosthetic adverse events were observed. After 4 years, the implant survival rate was 100%, minor peri-implant bleeding on probing was reported, and very stable peri-implant bone levels were observed. The pink aesthetic score showed that the prosthetic components were well integrated, and the peri-implant soft tissues were stable. Conclusions: Within the limits of this case series, these results suggest that emerging digital workflows allow the manufacture of final custom-made abutments and provisional crowns prior to surgery. This individualised OAOT procedure may reduce cement-related complications and improve aesthetic outcomes by optimising soft tissue healing with prosthetic components. However, such protocols have evolved towards full digital workflows, and comparative clinical trials are needed. [less ▲]

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See detailFictions de l’œuvre. Projets et textes possibles dans les romans de la vie littéraire
Saint-Amand, Denis ULiege

in Cahiers ReMIX (in press)

Le monde des études littéraires a vu se développer, au cours de ces dernières années, une théorie des textes possibles qui confronte la réception traditionnelle des œuvres (c’est-à-dire la façon dont leur ... [more ▼]

Le monde des études littéraires a vu se développer, au cours de ces dernières années, une théorie des textes possibles qui confronte la réception traditionnelle des œuvres (c’est-à-dire la façon dont leur lecture se concrétise la plupart du temps et le commentaire qu’on en livre habituellement) à une réinvention de leur signification, tirant parti des impensés de la fiction, des non-dits, des interactions interrompues, des blancs, des inférences labiles et autres zones creuses du récit qui offrent des prises pour une renégociation herméneutique. À côté des réinventions herméneutiques des œuvres classiques, de l’approche génétique et du fantasme programmatique autour des productions perdues, la critique des textes possibles aurait tout à gagner à explorer un continent fictionnel, fructueux en termes d’œuvres en puissance et qui recèle d’indications sur l’évaluation des modes et tendances d’une époque émanant des représentations des écrivains eux-mêmes : les œuvres imaginaires qui n’existent qu’en tant qu’elles sont inscrites dans d’autres œuvres, qui en esquissent les contours, les présentent voire les citent. Celles-là sont au cœur de la présente enquête, menée à partir du corpus rassemblé dans la base de données du GREMLIN ; on interroge dans cette contribution la façon dont, par métonymie, elles contribuent à une représentation fictionnelle de la vie littéraire. [less ▲]

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See detailOn the length of monotone paths in polyhedra
Blanchard, Moise; De Loera, Jesus; Louveaux, Quentin ULiege

in SIAM Journal on Discrete Mathematics (in press)

Motivated by the problem of bounding the number of iterations of the Simplex algorithm we investigate the possible lengths of monotone paths followed inside the oriented graphs of polyhedra (oriented by ... [more ▼]

Motivated by the problem of bounding the number of iterations of the Simplex algorithm we investigate the possible lengths of monotone paths followed inside the oriented graphs of polyhedra (oriented by the objective function). We consider both the shortest and the longest monotone paths and estimate the monotone diameter and height of polyhedra. Our analysis applies to transportation polytopes, matroid polytopes, matching polytopes, shortest-path polytopes, and the TSP, among others. We begin by showing that combinatorial cubes have monotone diameter and Bland simplex height upper bounded by their dimension and that in fact all monotone paths of zonotopes are no larger than the number of edge directions of the zonotope. We later use this to show that several polytopes have polynomial-size monotone diameter. In contrast, we show that for many well-known combinatorial polytopes, the height is at least exponential. Surprisingly, for some famous pivot rules, e.g., greatest improvement and steepest edge, these same polytopes have polynomial-size simplex paths. [less ▲]

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See detailA Connectivity-Based Psychometric Prediction Framework for Brain-Behavior Relationship Studies.
Wu, Jianxiao; Eickhoff, Simon B.; Hoffstaedter, Felix et al

in Cerebral cortex (New York, N.Y. : 1991) (in press)

The recent availability of population-based studies with neuroimaging and behavioral measurements opens promising perspectives to investigate the relationships between interindividual variability in brain ... [more ▼]

The recent availability of population-based studies with neuroimaging and behavioral measurements opens promising perspectives to investigate the relationships between interindividual variability in brain regions' connectivity and behavioral phenotypes. However, the multivariate nature of connectivity-based prediction model severely limits the insight into brain-behavior patterns for neuroscience. To address this issue, we propose a connectivity-based psychometric prediction framework based on individual regions' connectivity profiles. We first illustrate two main applications: 1) single brain region's predictive power for a range of psychometric variables and 2) single psychometric variable's predictive power variation across brain region. We compare the patterns of brain-behavior provided by these approaches to the brain-behavior relationships from activation approaches. Then, capitalizing on the increased transparency of our approach, we demonstrate how the influence of various data processing and analyses can directly influence the patterns of brain-behavior relationships, as well as the unique insight into brain-behavior relationships offered by this approach. [less ▲]

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See detailPresumptive acute myeloid leukemia in a Pelomedusa subrufa turtle
Melin, Marie; Vlaemynck, Frederic; Skeldon, Niki et al

in Veterinary Clinical Pathology (in press)

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See detailGreen composites based on thermoplastic starches and various natural plant fibers: Impacting parameters of the mechanical properties using machine-learning
Morin, Sophie ULiege; Dumoulin, Lionel ULiege; Delahaye, Louise ULiege et al

in Polymer Composites (in press)

Multivariate analyses on formulation and mechanical behavior of nonwoven and nonoriented natural fibers reinforced thermoplastic starch (TPS) composites were performed. Glycerol and water were considered ... [more ▼]

Multivariate analyses on formulation and mechanical behavior of nonwoven and nonoriented natural fibers reinforced thermoplastic starch (TPS) composites were performed. Glycerol and water were considered as TPS plasticizers. Fibers composition (i.e., cellulose, hemicellulose, lignin), fibers morphology (fibers length), starch composition (i.e., amylose/amylopectin ratio) as well as the processing conditions (i.e., temperature, rotor speed, relative humidity during aging) were evaluated for their ability to affect the elastic modulus, tensile strength, and elongation at break of the final materials. Multivariate linear regressions were computed to unveil the importance of each variable on the mechanical behavior. Fibers composition impacted the most the models: cellulose maximization improved the elastic modulus and tensile strength while lignin reduced the elastic modulus and hemicellulose decreased the tensile strength. TPS plasticizers, temperature, and rotor speed of the process were negatively impacting the elastic modulus but in a lesser extent than the fiber composition. Within the range of the created database, the selected variables and attributed coefficients were permitted to explain the variability. The produced models revealed that complex and yet uninvestigated interactions are to be considered within TPS-based biocomposites. Therefore, this work discusses and suggests a “must-have” list of variables for comparable analyses of new TPS-based biocomposites using natural fibers as reinforcement. [less ▲]

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See detailOrgano-mineral associations largely contribute to the stabilization of century-old pyrogenic organic matter in cropland soils
Burgeon, Victor ULiege

in Geoderma (in press)

Understanding the processes underlying carbon (C) stability in soils is of utmost importance in the context of climate change. In this setting, biochar is often studied for its persistence in soils and ... [more ▼]

Understanding the processes underlying carbon (C) stability in soils is of utmost importance in the context of climate change. In this setting, biochar is often studied for its persistence in soils and reported to have positive impacts on soil fertility. Whilst recent research has mostly focused on the short-term effects of biochar amendments to soil, a better understanding of its long-term persistence in soils is needed. Our study focuses on agricultural soils enriched in charcoal residues, produced in preindustrial kiln sites ca. 220 years ago, as a proxy for aged biochar. Our aim is to better understand the processes governing the long-term persistence of pyrogenic organic matter (PyOM) in cultivated soils. To achieve this, we focus on i) the effect of PyOM on soil aggregation, ii) its distribution amongst soil fractions and iii) its chemical and thermal properties. For this purpose, we combined a soil particle size-density fractionation with elemental and thermal analyses on topsoil samples collected in charcoal enriched (CHAR) and adjacent reference (REF) soils in a conventionally cropped field in Wallonia (Belgium). The presence of charcoal in soils resulted in a 91 ± 34% higher C content in CHAR soils than REF soils, of which 84 to 94% was PyOM and 6 to 16% was additional non-PyOM. In CHAR soils, macroaggregation was promoted at the expense of microaggregation (CHARMACRO = 48.9 ± 12.8; CHARMICRO = 25.5 ± 8.3 g 100 g−1 soil) whereas these were similar in REF soils (REFMACRO = 41.3 ± 9.5; REFMICRO = 36.0 ± 8.7 g 100 g−1 soil). Elemental and thermal analyses revealed that PyOM did not only occur as free light fractions but was also occluded in aggregates or sorbed onto mineral phases (56.4 ± 22.9% of total PyOM) suggesting PyOM may be further stabilized through organo-mineral associations. Century-old PyOM showed increased H:C and O:C atomic ratios compared to recently pyrolyzed OM, particularly in occluded as opposed to free light fractions, vouching for the functionalization of its surfaces. Furthermore, regardless of high C contents in CHAR soils, similar C:N ratios between studied soils in mineral dominated fractions suggested increased amounts of N-rich non-PyOM in charcoal rich soils. Our results demonstrate that, over centuries in cultivated soils, PyOM plays an active role in aggregation patterns. We conclude that century old PyOM is broken down from coarse to fine particles, and through functionalization of its surfaces contributes to organo-mineral associations. Beyond its intrinsic chemical recalcitrance, the long-term persistence of biochar is enhanced by occlusion and sorption processes. 1. [less ▲]

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See detailOrganizational identification as a mediator for the effects of psychological contract breaches on organizational citizenship behavior: Insights from the perspective of ethnic minority employees
Tufan, Pinar ULiege; Wendt, Hein

in European Management Journal (in press)

This study examines the contribution of the psychological contract (PC) framework to the understanding of ethnic minority employees’ employment relationships. First, it tests the generalizability of PC ... [more ▼]

This study examines the contribution of the psychological contract (PC) framework to the understanding of ethnic minority employees’ employment relationships. First, it tests the generalizability of PC types (transactional, relational, and balanced) observed in the general population to ethnic minority employees. Then, to further address the unique needs and motivators of minority employees, this study considers diversity-related PCs. It adopts social exchange theory to explain how transactional, relational, balanced, and diversity-related PC breaches predict organizational citizenship behavior (OCB). Moreover, it draws insights from social identity theory and examines the mediating role of organizational identification in the relationship between types of PC breach and OCB. Data from 361 Turkish employees working as ethnic minorities in Belgium indicate that relational and diversity-related PC breaches predict OCB partially via organizational identification while transactional and balanced PC breaches directly affect OCB. [less ▲]

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See detailTraces et matérialités de l’amitié entre Sartre et Giacometti
Franck, Thomas ULiege

in Études Sartriennes (in press), 25

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See detailTiwouh: an enriched technology-based solution for communication interventions
Fage, Charles ULiege; Giblet, Sarah ULiege; Jaspard, Marie et al

in Association for the Advancement of Modelling and Simulation Techniques in Enterprises (in press)

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See detailMotivations to refuse or participate in self-reported delinquency surveys: A qualitative study among Belgian juveniles in custody
Gregoire, Julie; Mathys, Cécile ULiege

in European Journal on Criminal Policy and Research (in press)

Several factors were investigated that relate to motivation about participation in self-reported delinquency (SRD) questionnaires among a specific and relevant population: youths in custody. Three ... [more ▼]

Several factors were investigated that relate to motivation about participation in self-reported delinquency (SRD) questionnaires among a specific and relevant population: youths in custody. Three research questions were identified: 1. Explore the major reasons why a youth does or does not agree to participate in an SRD questionnaire; 2. Examine the mode of questionnaire administration (Web or paper–pencil); 3. Examine the role of pre- and postpaid incentives. These questions were also investigated with regard to gender. The study included a sample of 30 youths from two Belgian custodial facilities (boys = 20, girls = 10; age 12–17 years) who initially agreed to or refused to participate in an SRD questionnaire. A focus group method was used to collect data across 3 steps, according to the research questions. Results identified 4 interrelated types of motives shared among boys and girls as they agreed to or refused to participate in the SRD questionnaire. The Web version of the questionnaire was slightly more preferred by all the sample, and the incentive was clearly perceived as useless or even harmful with respect to their motivation to participate. This article discusses implications for further research with juveniles in custody and the need to focus careful attention on how information about an SRD questionnaire is presented. An appendix with principal tips from this study is included with this article. [less ▲]

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See detailOne tooth-One time (1T1T), immediate loading of posterior single implants with the final crown: Two-year results of a case series.
LAMBERT, France ULiege; Eldafrawy, Maher ULiege; BEKAERT, Sandrine ULiege et al

in International Journal of Oral Implantology: Implantologist (in press)

AIMS: The aim of this study was to evaluate the two-year outcomes of the One Tooth-One Time (1T1T) completely digital workflow, allowing the immediate loading of a single implant in the posterior region ... [more ▼]

AIMS: The aim of this study was to evaluate the two-year outcomes of the One Tooth-One Time (1T1T) completely digital workflow, allowing the immediate loading of a single implant in the posterior region with a final CAD-CAM crown made of a polymer-infiltrated ceramic network (PICN). MATERIALS AND METHODS: A series of 10 implants were placed, and an intra-oral scan was taken after the surgery. A final screw-retained PICN crown was manufactured chair-side and placed the same day in full occlusion. Marginal peri-implant bone changes and soft-tissue health were evaluated, as well as restoration performance using World Dental Federation criteria and Pink and White Esthetic Scores. Patient-related outcome measures (PROMs) and time consumption data were collected. RESULTS: After two years, the implant survival rate was 100%. The debonding of one crown from its Titanium Base led to a 90% prosthodontic survival rate and the remaining crowns were all considered successful. The mean marginal peri-implant bone changes yielded 0.87 (SD: 0.96) and 0.55 (SD: 0.53) mm after one and two years, respectively. Mild or no inflammation of peri-implant soft tissue was observed in most implants. The overall treatment time reached 175 min and PROMs displayed high patient satisfaction. CONCLUSIONS: This study constitutes the first report considering immediate loading of a single implant in the posterior region with a final crown in occlusion. In this case-series, the two-year outcomes of the 1T1T protocol seem rather promising and fulfil patient expectations. However, those preliminary results need to be confirmed by randomized control trials and patient selection is probably a key factor in this procedure success. [less ▲]

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See detailEffects of the class II Carriere motion® appliance on children: A randomized controlled trial
Clermont, Anaïs; Albert, Adelin ULiege; BRUWIER, Annick ULiege

in Journal of Clinical Orthodontics (in press)

Objective: To assess the skeletal, dento-alveolar and dental effects of the class II Carriere motion® on young subjects. Materials and Methods: 32 class II subjects (mean age 9.4 ± 1.6 years) were ... [more ▼]

Objective: To assess the skeletal, dento-alveolar and dental effects of the class II Carriere motion® on young subjects. Materials and Methods: 32 class II subjects (mean age 9.4 ± 1.6 years) were randomly allocated to either the Carriere motion® appliance group (n=15), or to a control group (n=17). Digital dental cast measurements and cephalometric analysis were performed before treatment (T0), at removal of the device for the appliance group, and after a period of 9 months for the control group (T1). The duration of treatment was recorded and the patient’s satisfaction with the appliance was assessed through a questionnaire. Results: The effects of the Carriere Motion leading to Class I were essentially dento-alveolar. Significant decreases of ANB and SNA angles were evidenced, as well as an increase by 1.3 degree of FMA angle compared to control subjects. Distalization and distal rotation of upper molars were observed. The mandibular teeth mesialized and the lower incisors proclined. A clockwise rotation of the occlusal plane occurred. The treatment lasted 7.6 ± 1.6 months with a mean of 6.1 ± 1.1 appointments. The patient experience with the Carriere motion® was quite positive. Conclusion: The Carriere motion® proved its efficiency in correcting class II malocclusion, essentially by dento-alveolar effects. This easy-to-use appliance is indicated in early orthodontic treatment, when the correction is urgently required (prevention of incisor trauma in case of large overjet, periodontal risk for upper incisor in case of deep bite and sleep apnea). [less ▲]

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See detailBack to the Future: the Democracy of Yesterday and Tomorrow in the Speeches of the Rassemblement National and the Freiheitliche Partei Österreichs
Debras, François ULiege

in Journal of Contemporary European Studies (in press)

In France, the Rassemblement National and, in Austria, the Freiheitliche Partei Österreichs aim to “recover”, “restore” or “protect” democracy. In this article, I will study their use of the term ... [more ▼]

In France, the Rassemblement National and, in Austria, the Freiheitliche Partei Österreichs aim to “recover”, “restore” or “protect” democracy. In this article, I will study their use of the term “democracy” by focusing on its temporal dimension. Their discourse tells a story, that of a glorious past which should be revived. Adopting a critical discourse analysis approach, I will answer the following questions: what kind of temporality is conveyed by the term “democracy”?, and, if “democracy” is perceived as a “lost world”, then what vision do those politicians who support the ideology of the two political parties have of tomorrow’s “democracy”? I would maintain that whilst these parties present themselves as agents of a democratic renewal, their vision of “democracy” remains traditional, i.e. essentially representative and vertical. The term “direct democracy” is limited to particular subjects (the EU, immigration, international agreements) and these parties are critical of electoral reforms or new forms of participation. [less ▲]

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See detailMigrant jobseekers, right of residence and access to welfare benefits: One step forward, two steps backwards?
Tecqmenne, Maxime ULiege

in European Law Review (in press)

In the aftermath of the Court’s judgments in Dano and Alimanovic, there remained considerable uncertainty about the interplay between the equal treatment guarantees vested in Union citizens by Articles 18 ... [more ▼]

In the aftermath of the Court’s judgments in Dano and Alimanovic, there remained considerable uncertainty about the interplay between the equal treatment guarantees vested in Union citizens by Articles 18, 21 and 45 TFEU and the different legislative measures adopted to give effect to these Treaty provisions. In this context, this article seeks to cast some light on the rather ambiguous relationship between Directive 2004/38 and Regulation 492/2011. It is essentially suggested that the limitations on the right of equal treatment featured in Article 24(2) of the Citizenship Directive cannot be relied upon as such in order to circumscribe the equal treatment guarantees conferred upon “workers” by Article 7(2) of the Workers’ Regulation. At the same time, though, it would appear that the Court has accepted – albeit somewhat implicitly – that the Member States may effectively restrict migrant workers’ equality rights on the basis of integration requirements inspired to some extent by the requirements expressed in the Directive. [less ▲]

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See detailLa Vigna Manzi a Garaguso (MT) : Vecchi scavi, ricerche in corso e prospettive di studio di un importante sito indigeno
Cuvelier, Graham ULiege; Morard, Thomas ULiege; Motta, Lucie

in Siris: Studi e Ticerche della Scuola di Specializzazione in Archeologia di Matera (in press)

This article traces the history of the archaeological research conducted on the site of the Vigna Manzi in Garaguso starting from the excavation of Vittorio Di Cicco in 1916 (which uncovered the famous ... [more ▼]

This article traces the history of the archaeological research conducted on the site of the Vigna Manzi in Garaguso starting from the excavation of Vittorio Di Cicco in 1916 (which uncovered the famous “Dea di Garaguso” and her tempietto) to the five surveys run by Jean-Paul Morel between 1969 and 1970. It then presents the results of the campaign led by Jean-Marc Moret in 2008 as well as the reopening and the prospects of the study of this site by the University of Liège. [less ▲]

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See detailLong-term stability of 25-hydroxyvitamin D: importance of the analytical method and of the patient matrix.
Cavalier, Etienne ULiege

in Clinical chemistry and laboratory medicine (in press)

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See detailRôles et impacts des pharmaciens en Belgique : une revue de littérature exploratoire
Frison, Corentin ULiege; Philippe, Geneviève ULiege; Mehuys, Els et al

in Pharmacien Hospitalier et Clinicien (in press)

Introduction > There is a growing number of articles describing the roles and impacts of the activity of pharmacists and their collaborators in the community and in health care settings. However, there is ... [more ▼]

Introduction > There is a growing number of articles describing the roles and impacts of the activity of pharmacists and their collaborators in the community and in health care settings. However, there is no profile of this literature related to pharmacy practice in Belgium. Method > This is a literature review. The main objective was to gather evidence in order to describe and highlight the different characteristics of the role of pharmacists and the impacts of their activities in Belgium. The literature search was carried out in three databases, PubMed, Embase and CINAHL between 01/01/2006 and 30/09/2019. Results > Of the 232 articles identified, 65 were included for analysis. The studies included only descriptive data (73.9%, 48/65) or descriptive data associated with measures of pharmacist impact (26.1%, 17/65). The study highlighted the presence of pharmacists exercising one or the other of the 21 pharmaceutical activities with, in descending order, medication reviews, advice to patients (i.e. ad hoc process that targets a drug), therapeutic education of patients (e.g. continuous, interdisciplinary process, which aims not only to inform but also to train and evaluate the patient) and drug reconciliation activities. Studies were conducted only in pharmacies (53.8%, 35/65), hospitals (29.2%, 19/65), both (7.7%, 5/65) and other practice settings (9.2%, 6/65). Seventeen of the 65 included studies included a measure of the impact of the pharmacist's presence. Of the 35 impact measures associated with pharmaceutical interventions, 23 included positive effects, 12 neutral effects and none of the negative effects. Conclusion > This is the first review of the literature on the roles and impacts of the pharmacist in Belgium. Sixty-five articles were selected, 17 of which included measures of the impact of pharmaceutical activity. Of the 35 impact measures associated with pharmaceutical interventions, 23 included positive effects, 12 neutral effects and none of the negative effects. These data are in phase with the action plan for the development of clinical pharmacy in Belgian hospitals for the period 2015–2020. [less ▲]

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See detailAberrations chromatiques : de l’émulsion au pixel
Thonon, Jonathan ULiege

in Cahiers Louis Lumière (in press)

Dans l’une de ses conversations avec Joachim Gasquet sur le sens de sa peinture (et de la peinture en général), Cézanne aborde de front la conception qu’il se fait de la couleur, dans son rapport à la ... [more ▼]

Dans l’une de ses conversations avec Joachim Gasquet sur le sens de sa peinture (et de la peinture en général), Cézanne aborde de front la conception qu’il se fait de la couleur, dans son rapport à la profondeur picturale et de son articulation à la surface : « La nature n'est pas en surface ; elle est en profondeur. Les couleurs sont l'expression, à cette surface, de cette profondeur. Elles montent des racines du monde ». Cet « organisme de couleurs » que constitue le monde est transcrit dans la peinture de Cézanne par une dynamique symbiotique de la couleur et du dessin, de la ligne et du pan. La couleur restitue, par sa masse, son surgissement, son homogénéité, presque sa viscosité, la véritable chaire perceptive du monde ; une vision qui tient à distance la perspective géométrique, photographique, cinématographique fondée sur la transparence et qui repose, comme le signale Merleau-Ponty, sur la « réversibilité des dimensions » (surface-profondeur) et l’entrelacement des choses. C’est cette épaisseur du visible rendu par la couleur que l’économie de l’image numérique nous permet de redécouvrir, moins dans le registre de la « tactilité » de l’image et la picturalité du pixel, que par l’intégration, entre le support et l’image (parfois indiscernables dans le régime optique), d’un « corps » algorithmique qui règle l’actualisation du visible. Certains défauts techniques du dispositif numérique, aujourd’hui élevés au rang de pratique artistique, permettent de révéler cette matrice qui utilise alors la couleur et la coulure comme mode de visibilité. C’est le cas du Datamoshing, technique de composition numérique qui revisite tout en la radicalisant la pratique de l’incrustation vidéo. Basée sur la perturbation volontaire d’éléments de la matrice, cette technique transforme les couleurs en une forme malléable et fluide révélant ainsi leur double nature spatiale : elles sont à la fois dans l’espace de l’image et l’espace de l’image lui-même. Ces expériences de défigurations d’images s’inscrivent dans le registre des « aberrations chromatiques » dont nous proposons ici une rapide généalogie avant d’interroger la couleur digitale dans ses spécificités. [less ▲]

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See detailRisk factors for a severe form of COVID-19 after allogeneic haematopoietic stem cell transplantation : a SFGM-TC multicentre cohort study
Xhaard, A.; Xhaard, C.; d'Aveni, M. et al

in British Journal of Haematology (in press)

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See detailOral hygiene instructions and methods: a European survey among dental professionals – the eSIP study
Garyga, Valentin; SEIDEL, Laurence ULiege; Gagnot, Gilles et al

in Oral Health and Preventive Dentistry (in press)

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See detailA model of the optimal allocation of government expenditures
Pestieau, Pierre ULiege; Fan, Simon; Pang, Yu

in Journal of Public Economic Theory (in press)

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See detailWhich access to which assets for an effective liberalization of the rail sector
Bougette, Patrice; Gautier, Axel ULiege; Marty, Frederic

in Competition and Regulation in Network Industries (in press)

In the European rail industry, to enable competition in the market, entrants should be granted access to a large set of complementary services, beyond access to the tracks. For an efficient and effective ... [more ▼]

In the European rail industry, to enable competition in the market, entrants should be granted access to a large set of complementary services, beyond access to the tracks. For an efficient and effective entry, temporary access to quasi-essential complementary assets like rolling stock, mechanical maintenance workshops, data, schedules, etc. is also required. In the liberalized rail sector, several observed anticompetitive practices involve distorted access to these quasi-essential facilities. Therefore, competition agencies must deal with litigation between the incumbent and new entrants. Most cases have been settled, resulting in commitments from the incumbent. We argue that such transitory and case-by-case remedies fail to produce favorable conditions for a secure and efficient entry. Thus, we propose to systematize such remedies through asymmetric and enduring ex-ante regulation. [less ▲]

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See detailGoogle BERT and Text Similarity Applied to the Analysis of Epistolary Texts
Valenti, Gianluca ULiege; Zeisberg, Alexander

in Cognitive Philology (in press), (14),

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See detailOral hygiene instructions and methods: a comparative survey of European general dentists, periodontists and dental hygienists
Garyga, Valentin; SEIDEL, Laurence ULiege; Gagnot, Gilles et al

in Oral Health and Preventive Dentistry (in press)

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See detailCompte-rendu de J. Gayon, L’Identité. Dictionnaire encyclopédique
Recchia, Fabio ULiege

in Revue Philosophique de Louvain (in press), 4/2020-2021

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See detailA search for transiting planets around hot subdwarfs: I. Methods and performance tests on light curves from Kepler, K2, TESS, and CHEOPS
Van Grootel, Valérie ULiege; Pozuelos Romero, Francisco José ULiege; Thuillier, Antoine ULiege et al

in Astronomy and Astrophysics (in press)

Context. Hot subdwarfs experienced strong mass loss on the red giant branch (RGB) and are now hot and small He-burning objects. These stars constitute excellent opportunities for addressing the question ... [more ▼]

Context. Hot subdwarfs experienced strong mass loss on the red giant branch (RGB) and are now hot and small He-burning objects. These stars constitute excellent opportunities for addressing the question of the evolution of exoplanetary systems directly after the RGB phase of evolution. Aims. In this project we aim to perform a transit survey in all available light curves of hot subdwarfs from space-based telescopes (Kepler, K2, TESS, and CHEOPS) with our custom-made pipeline SHERLOCK in order to determine the occurrence rate of planets around these stars as a function of orbital period and planetary radius. We also aim to determine whether planets that were previously engulfed in the envelope of their red giant host star can survive, even partially, as a planetary remnant. Methods. For this first paper, we performed injection-and-recovery tests of synthetic transits for a selection of representative Kepler, K2, and TESS light curves to determine which transiting bodies in terms of object radius and orbital period we will be able to detect with our tools. We also provide estimates for CHEOPS data, which we analyzed with the pycheops package. Results. Transiting objects with a radius $\lesssim$ 1.0 $R_{\Earth}$ can be detected in most of the Kepler, K2, and CHEOPS targets for the shortest orbital periods (1~d and shorter), reaching values as low as $\sim$0.3 $R_{\Earth}$ in the best cases. Sub-Earth-sized bodies are only reached for the brightest TESS targets and for those that were observed in a significant number of sectors. We also give a series of representative results for larger planets at greater distances, which strongly depend on the target magnitude and on the length and quality of the data. Conclusions. The TESS sample will provide the most important statistics for the global aim of measuring the planet occurrence rate around hot subdwarfs. The Kepler, K2, and CHEOPS data will allow us to search for planetary remnants, that is, very close and small (possibly disintegrating) objects. [less ▲]

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See detailCan video-assistance improve the quality of pediatric dispatcher-assisted cardiopulmonary resuscitation? (IN PROGRESS)
PETERS, Michaël ULiege; Stipulante, Samuel ULiege; Cloes, Véronique et al

in Pediatric Emergency Care (in press)

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See detailSwallowing in individuals with disorders of consciousness: A cohort study
MELOTTE, Evelyne ULiege; MAUDOUX, Audrey ULiege; DELHALLE, Sabrina ULiege et al

in Annals of Physical and Rehabilitation Medicine (in press)

Background. After a period of coma, a proportion of individuals with severe brain injury remain in an altered state of consciousness before regaining partial or complete recovery. Individuals with ... [more ▼]

Background. After a period of coma, a proportion of individuals with severe brain injury remain in an altered state of consciousness before regaining partial or complete recovery. Individuals with disorders of consciousness (DOC) classically receive hydration and nutrition through an enteral feeding tube. However, the real impact of the level of consciousness on an individual’s swallowing ability remains poorly investigated. Objective. We aimed to document the incidence and characteristics of dysphagia in DOC individuals and to evaluate the link between different components of swallowing and the level of consciousness. Methods. We analyzed clinical data on the respiratory status, oral feeding and otolaryngologic examination of swallowing in DOC individuals. Univariate and multivariate logistic regression was used to analyse the association of components of swallowing and participant groups (i.e., unresponsive wakefulness syndrome [UWS] and minimally conscious state [MCS]). Results. We included 92 individuals with DOC (26 UWS and 66 MCS). Overall, 99% of the participants showed deficits in the oral and/or pharyngeal phase of swallowing. As compared with the MCS group, the UWS group more frequently had a tracheostomy (69% vs 24%), with diminished cough reflex (27% vs 54%) and no effective oral phase (0% vs 21%). Conclusion. Almost all DOC participants had severe dysphagia. Some components of swallowing (i.e., tracheostomy, cough reflex and efficacy of the oral phase of swallowing) were related to consciousness. In particular, no UWS participant had an efficient oral phase, which suggests that its presence may be a sign of consciousness. In addition, no UWS participant could be fed entirely orally, whereas no MCS participant orally received ordinary food. Our study also confirms that objective swallowing assessment can be successfully completed in DOC individuals and that specific care is needed to treat severe dysphagia in DOC. [less ▲]

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See detailFrightening Times
Bordini, Davide ULiege; Torrengo, Giuliano

in European Journal of Philosophy (in press)

In this paper, we discuss the inherent temporal orientation of fear, a matter on which philosophers seem to have contrasting opinions. According to some, fear is inherently presentoriented; others instead ... [more ▼]

In this paper, we discuss the inherent temporal orientation of fear, a matter on which philosophers seem to have contrasting opinions. According to some, fear is inherently presentoriented; others instead maintain that it is inherently future-oriented or that it has no inherent temporal orientation at all. Despite the differences, however, all these views seem to understand fear’s temporal orientation as one-dimensional—that is, as uniquely determined by the represented temporal location of the intentional object of fear. By contrast, we present a view that introduces a two-dimensional account of fear’s temporal orientation. On such a view, we can say that fear is inherently future-oriented, independently of its being about something in the present or in the future. [less ▲]

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See detailA near-infrared interferometric survey of debris-disk stars. VII. The hot/warm dust connection
Absil, Olivier ULiege; Marion, L.; Ertel, S. et al

in Astronomy and Astrophysics (in press)

Context. Hot exozodiacal dust has been shown to be present in the innermost regions of an increasing number of main sequence stars over the past fifteen years. The origin of hot exozodiacal dust and its ... [more ▼]

Context. Hot exozodiacal dust has been shown to be present in the innermost regions of an increasing number of main sequence stars over the past fifteen years. The origin of hot exozodiacal dust and its connection with outer dust reservoirs remains however unclear. Aims. We aim to explore the possible connection between hot exozodiacal dust and warm dust reservoirs (≥ 100 K) in asteroid belts. Methods. We use precision near-infrared interferometry with VLTI/PIONIER to search for resolved emission at H band around a selected sample of 62 nearby stars showing possible signposts of warm dust populations. Results. Our observations reveal the presence of resolved near-infrared emission around 17 out of 52 stars with sufficient data quality, four of which are shown to be due to a previously unknown stellar companion. The 13 other H-band excesses are thought to originate from the thermal emission of hot dust grains, close to their sublimation temperature. Taking into account earlier PIONIER observations, where some stars with warm dust were also observed, and after re-evaluating the warm dust content of all our PIONIER targets through spectral energy distribution modeling, we find a detection rate of 17.1(+8.1)(-4.6)% for H-band excess around main sequence stars hosting warm dust belts, which is statistically compatible with the occurrence rate of 14.6(+4.3)(-2.8)% found around stars showing no signs of warm dust. After correcting for the sensitivity loss due to partly unresolved hot disks, under the assumption that they are arranged in a thin ring around their sublimation radius, we however find tentative evidence at the 3σ level that H-band excesses around stars with outer dust reservoirs (warm or cold) could be statistically larger than H-band excesses around stars with no detectable outer dust. Conclusions. Our observations do not suggest a direct connection between warm and hot dust populations, at the sensitivity level of the considered instruments, although they bring to light a possible correlation between the level of H-band excesses and the presence of outer dust reservoirs in general. [less ▲]

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See detailUniversal and macro-areal patterns in the lexicon. A case-study in the perception-cognition domain
Georgakopoulos, Athanasios ULiege; Grossman, Eitan; Nikolaev, Dmitri et al

in Linguistic Typology (in press)

This paper investigates universal and areal structures in the lexicon as manifested by colexification patterns in the semantic domains of perception and cognition, based on data from both small and large ... [more ▼]

This paper investigates universal and areal structures in the lexicon as manifested by colexification patterns in the semantic domains of perception and cognition, based on data from both small and large datasets. Using several methods, including weighted semantic maps, formal concept lattices, correlation analysis, and dimensionality reduction, we identify colexification patterns in the domains in question and evaluate the extent to which these patterns are specific to particular areas. This paper contributes to the methodology of investi-gating areal patterns in the lexicon, and identifies a number of cross-linguistic regularities and of area-specific properties in the structuring of lexicons. [less ▲]

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See detailA leaf point documents hunting with spears in the Middle Paleolithic at Hohle Fels, Germany
Rots, Veerle ULiege; Coppe, Justin ULiege; Conard, Nicholas J.

in Mitteilungen der Gesellschaft für Urgeschichte (in press), 30

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See detailLes promesses communicationnelles d’une science aux prises avec le monde: Étude comparée des dispositifs médiatiques Hypotheses.org et The Conversation
Mayeur, Ingrid ULiege

in Études de Communication (in press), 56

La présente contribution entend mener l’étude des promesses communicationnelles portées par les dispositifs médiatiques requérant la participation des chercheurs voire, dans certains cas, du grand public ... [more ▼]

La présente contribution entend mener l’étude des promesses communicationnelles portées par les dispositifs médiatiques requérant la participation des chercheurs voire, dans certains cas, du grand public, en prenant pour terrain d’analyse deux sites agissant sur des plans distincts : l’un opérant sur une scène d’énonciation scientifique, Hypotheses.org, l’autre sur une scène d’énonciation journalistique, The Conversation. Ces promesses seront lues suivant une approche narrative et l’on précisera le rôle joué par la participation dans le récit de chaque organisation médiatique : on montrera ainsi comment la participation contribue à charger de valeur la communication des savoirs scientifiques dans ces dispositifs médiatiques. Enfin, nous questionnerons l’adhésion à l’impératif de transparence dont ces promesses se font l’écho, sous des modalités diverses, et la manière dont il influence la circulation sociale des savoirs. [less ▲]

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See detailNeural responses to heartbeats detect residual signs of consciousness during resting state in post-comatose patients
Candia-Rivera, D; Annen, Jitka ULiege; Gosseries, Olivia ULiege et al

in Journal of Neuroscience (in press)

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See detailHigh contrast imaging at 10 microns, a search for exoplanets around: Eps Indi A, Eps Eri, Tau Ceti, Sirius A and Sirius B
Pathak, P.; Petit dit de la Roche, D. J. M.; Kasper, M. et al

in Astronomy and Astrophysics (in press)

The direct imaging of rocky exoplanets is one of the major science goals for upcoming large telescopes. The contrast requirement for imaging such planets is challenging. However, the mid-IR (InfraRed ... [more ▼]

The direct imaging of rocky exoplanets is one of the major science goals for upcoming large telescopes. The contrast requirement for imaging such planets is challenging. However, the mid-IR (InfraRed) regime provides the optimum contrast to directly detect the thermal signatures of exoplanets in our solar neighbourhood. We aim to exploit novel fast chopping techniques newly developed for astronomy with the aid of adaptive optics to look for thermal signatures of exoplanets around bright stars in the solar neighbourhood. We use the upgraded VISIR (Very Large Telescope Imager and Spectrometer for the mid-InfraRed) instrument with high contrast imaging (HCI) capability optimized for observations at 10~$\mu$m to look for exoplanets around five nearby ($d$ < 4 pc) stars. The instrument provides an improved signal-to-noise (S/N) by a factor of $\sim$4 in the N-band compared to standard VISIR for a given S/N and time. In this work we achieve a detection sensitivity of sub-mJy, which is sufficient to detect few Jupiter mass planets in nearby systems. Although no detections are made we achieve most sensitive limits within $<2''$ for all the observed targets compared to previous campaigns. For $\epsilon$ Indi A and $\epsilon$ Eri we achieve detection limits very close to the giant planets discovered by RV, with the limits on $\epsilon$ Indi A being the most sensitive to date. Our non-detection therefore supports an older age for $\epsilon$ Indi A. The results presented here show the promise for high contrast imaging and exoplanet detections in the mid-IR regime. [less ▲]

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See detailAcquiring the cardinal knowledge of number words : A conceptual replication.
Rousselle, Laurence ULiege; Vossius, Line ULiege

in Journal of Numerical Cognition (in press)

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See detailLessons from the Belgian experience with regulatory control during the COVID-19 pandemic for the implementation of the European IVD regulation 2017/746.
Vermeersch, Pieter; Cotton, Frédéric; De Smet, Dieter et al

in Acta Clinica Belgica (in press)

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See detailAnalytical relationships for imposing minimum length scale inthe robust Topology Optimization formulation
Trillet, Denis ULiege; Duysinx, Pierre ULiege; Fernandez Sanchez, Eduardo Felipe ULiege

in Structural and Multidisciplinary Optimization (in press)

When using the robust topology optimization formulation in the density framework, the minimum size of the solid and void phases must be imposed implicitly through the parameters that define the density ... [more ▼]

When using the robust topology optimization formulation in the density framework, the minimum size of the solid and void phases must be imposed implicitly through the parameters that define the density filter and the smoothed Heaviside projection. Finding these parameters can be time consuming and cumbersome, hindering a general code implementation of the robust formulation. Motivated by this issue, in this article we provide analytical expressions that explicitly relate the minimum length scale and the parameters that define it. The expressions are validated on a density-based framework. To facilitate the reproduction of results, MATLAB codes are provided. [less ▲]

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See detailMapping the human genetic architecture of COVID-19 by worldwide meta-analysis
The COVID-19 Host Genetics Initiative; Rahmouni, Souad ULiege; Georges, Michel ULiege et al

in Nature (in press)

The genetic makeup of an individual contributes to susceptibility and response to viral infection. While environmental, clinical and social factors play a role in exposure to SARS-CoV-2 and COVID-19 ... [more ▼]

The genetic makeup of an individual contributes to susceptibility and response to viral infection. While environmental, clinical and social factors play a role in exposure to SARS-CoV-2 and COVID-19 disease severity, host genetics may also be important. Identifying host-specific genetic factors indicate biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We formed a global network of researchers to investigate the role of human genetics in SARS-COV-2 infection and COVID-19 severity. We describe the results of three genome-wide association meta-analyses comprising up to 49,562 COVID-19 patients from 46 studies across 19 countries worldwide. We reported 13 genome-wide significant loci that are associated with SARS-CoV-2 infection or severe manifestations of COVID-19. Several of these loci correspond to previously documented associations to lung or autoimmune and inflammatory diseases. They also represent potentially actionable mechanisms in response to infection. We further identified smoking and body mass index as causal risk factors for severe COVID-19. The identification of novel host genetic factors associated with COVID-19, with unprecedented speed, was enabled by prioritization of shared resources and analytical frameworks. This working model of international collaboration provides a blue-print for future genetic discoveries in the event of pandemics or for any complex human disease. [less ▲]

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See detailLa faillite des liquidations déficitaires : The Usual Suspects
Aydogdu, Roman ULiege

in Revue de Droit Commercial Belge (in press)

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See detailExchange between drainage systems and surface flows during urban flooding: Quasi-steady and dynamic modelling in unsteady flow conditions
Kitsikoudis, Vasileios; Erpicum, Sébastien ULiege; Rubinato, Matteo et al

in Journal of Hydrology (in press)

The accurate modelling of urban flooding constitutes an integral part of flood risk assessment and management in residential and industrial areas. Interactions between drainage networks and surface runoff ... [more ▼]

The accurate modelling of urban flooding constitutes an integral part of flood risk assessment and management in residential and industrial areas. Interactions between drainage networks and surface runoff flows are commonly modelled based on weir/orifice equations; however, this approach has not been satisfactorily validated in unsteady flow conditions due to uncertainties in estimating the discharge coefficients and associated head losses. This study utilises experimental data of flow exchange between the sewer flow and the floodplain through a manhole without a lid to develop two alternate approaches that simulate this interaction and describe the associated exchange flow. A quasi-steady model links the exchange flow to the total head in the sewer pipe and the head losses in the sewer and the manhole, whilst a dynamic model takes also into account the evolution of the water level within the manhole at discrete time steps. The developed numerical models are subsequently validated against large-scale experimental data for unsteady sewer flow conditions, featuring variable exchange to the surface. Results confirmed that both models can accurately replicate experimental conditions, with improved performance when compared to existing methodologies based only on weir or orifice equations. [less ▲]

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See detailPer la costituzione di un database del romanesco rinascimentale
Valenti, Gianluca ULiege

in Rivista Italiana di Dialettologia (in press), 44

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See detailImpact of prior JAK-inhibitor therapy with ruxolitinib on outcome after allogeneic hematopoietic stem cell transplantation for myelofibrosis: a study of the CMWP of EBMT.
Kröger, Nicolaus; Sbianchi, Giulia; Sirait, Tiarlan et al

in Leukemia (in press)

JAK1/2 inhibitor ruxolitinib (RUX) is approved in patients with myelofibrosis but the impact of pretreatment with RUX on outcome after allogeneic hematopoietic stem cell transplantation (HSCT) remains to ... [more ▼]

JAK1/2 inhibitor ruxolitinib (RUX) is approved in patients with myelofibrosis but the impact of pretreatment with RUX on outcome after allogeneic hematopoietic stem cell transplantation (HSCT) remains to be determined. We evaluated the impact of RUX on outcome in 551 myelofibrosis patients who received HSCT without (n = 274) or with (n = 277) RUX pretreatment. The overall leukocyte engraftment on day 45 was 92% and significantly higher in RUX responsive patients than those who had no or lost response to RUX (94% vs. 85%, p = 0.05). The 1-year non-relapse mortality was 22% without significant difference between the arms. In a multivariate analysis (MVA) RUX pretreated patients with ongoing spleen response at transplant had a significantly lower risk of relapse (8.1% vs. 19.1%; p = 0.04)] and better 2-year event-free survival (68.9% vs. 53.7%; p = 0.02) in comparison to patients without RUX pretreatment. For overall survival the only significant factors were age > 58 years (p = 0.03) and HLA mismatch donor (p = 0.001). RUX prior to HSCT did not negatively impact outcome after transplantation and patients with ongoing spleen response at time of transplantation had best outcome. [less ▲]

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See detailComprehensive analysis of the immunomodulatory effects of rapamycin on human T cells in graft-versus-host disease prophylaxis
Ehx, Grégory ULiege; Ritacco, Caroline ULiege; HANNON, Muriel ULiege et al

in American Journal of Transplantation (in press)

Graft-versus-host disease (GVHD) is a major cause of toxicity after allogeneic hematopoietic cell transplantation (allo-HCT). While rapamycin (RAPA) is commonly used in GVHD prophylaxis in combination ... [more ▼]

Graft-versus-host disease (GVHD) is a major cause of toxicity after allogeneic hematopoietic cell transplantation (allo-HCT). While rapamycin (RAPA) is commonly used in GVHD prophylaxis in combination with a calcineurin inhibitor (CNI), the understanding of its mechanism of action on human T cells is still incomplete. Here, we performed an extensive analysis of RAPA effects on human T cells in a humanized mouse model of GVHD, in ex-vivo T-cell cultures and in patients given RAPA plus tacrolimus as GVHD prophylaxis after non-myeloablative allo-HCT. We demonstrate that RAPA mitigates GVHD by decreasing T-cell engraftment and differentiation, inhibiting CD8+ T-cell activation and increasing the long-term IL-2 secretion, thereby supporting regulatory T-cell (Treg) proliferation. In contrast, graft-versus-leukemia effects were not abrogated, as RAPA-treated T cells had increased resistance to apoptosis and retained their effector function and proliferative capacity upon re-stimulation. Importantly, we found that RAPA impact on Treg and CD8+ T cells was closely dependent upon IL-2 signaling and that therapeutic options interfering with IL-2, such as calcineurin inhibitors, antagonize the IL-2-dependent promotion of Treg mediated by RAPA. Our results suggest that RAPA immunological efficacy could be improved in combination with drugs having possible synergistic effects such as the hypomethylating agent 5-azacytidine. [less ▲]

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See detailFair Long-Term Care Insurance
Pestieau, Pierre ULiege; Leroux, Marie-Louise; Ponthiere, Grégory

in Social Choice and Welfare (in press)

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See detailL’expertise médico-légale dans l’Antiquité : le témoignage des papyrus grecs d’Égypte
Ricciardetto, Antonio ULiege

in Histoire, Médecine et Santé (in press)

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See detailMapping the human genetic architecture of COVID-19 by worldwide meta-analysis
Ganna, A.; BEGUIN, Yves ULiege

in Nature (in press)

The genetic makeup of an individual contributes to susceptibility and response to viral infection. While environmental, clinical and social factors play a role in exposure to SARS-CoV-2 and COVID-19 ... [more ▼]

The genetic makeup of an individual contributes to susceptibility and response to viral infection. While environmental, clinical and social factors play a role in exposure to SARS-CoV-2 and COVID-19 disease severity, host genetics may also be important. Identifying host-specific genetic factors indicate biological mechanisms of therapeutic relevance and clarify causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We formed a global network of researchers to investigate the role of human genetics in SARS-COV-2 infection and COVID-19 severity. We describe the results of three genome-wide association meta-analyses comprising 49,562 COVID-19 patients from 46 studies across 19 countries worldwide. We reported 15 genome-wide significant loci that are associated with SARS-CoV-2 infection or severe manifestations of COVID-19. Several of these loci correspond to previously documented associations to lung or autoimmune and inflammatory diseases. They also represent potentially actionable mechanisms in response to infection. We further identified smoking and body mass index as causal risk factors for severe COVID-19. The identification of novel host genetic factors associated with COVID-19, with unprecedented speed, was enabled by prioritization of shared resources and analytical frameworks. This working model of international collaboration a blue-print for future genetic discoveries in the event of pandemics or for any complex human disease. [less ▲]

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See detailLes références à la couleur dans les textes hippiatriques grecs
Ricciardetto, Antonio ULiege

in Pallas: Revue d'Études Antiques (in press)

Based on a survey references to colours in Greek hippiatrics text—especially in the Hippiatrica and in book 16 of the Geoponica—this paper examines the lexicon used by horsedoctors to designate colour and ... [more ▼]

Based on a survey references to colours in Greek hippiatrics text—especially in the Hippiatrica and in book 16 of the Geoponica—this paper examines the lexicon used by horsedoctors to designate colour and the contexts in which it appears, in order to better understand the importance given to colour terms. Colour adjectives are used in three sections of the texts: the external description of the animal (especially the coat and eyes), body fluids and pharmacology (simple and compound drugs). [less ▲]

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See detailL'effet des prix et des systèmes de tarification sur les quantités de déchets résidentiels : le cas de la Wallonie
Salem, Iman ULiege; Gautier, Axel ULiege

in Revue Economique (in press)

Price and non-price instruments are increasingly used to encourage households to reduce their waste and to increase sorting and recycling. In this paper, we test the effectiveness of these instruments ... [more ▼]

Price and non-price instruments are increasingly used to encourage households to reduce their waste and to increase sorting and recycling. In this paper, we test the effectiveness of these instruments using a recent complete panel dataset of the entire municipalities in Wallonia (Belgium). The municipalities are responsible for the implementation of the waste policy in a common regional framework and, interestingly, they have to make decisions regarding the price level, the pricing unit, and the waste streams collected at the curbside. Using a fixed effects panel two-step GMM, we show that curbside collection of organic waste reduces residual waste but also reduces the household sensitivity to prices. We also find that the weight-based pricing system has a significant impact on the reduction of residual waste, an effect that is increasing in the long-run, on the improvement of sorting and on the effectiveness of the price instruments. [less ▲]

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See detailHolomorphic cohomological convolution and Hadamard product
Dubussy, Christophe ULiege; Schneiders, Jean-Pierre ULiege

in Publications of the Research Institute for Mathematical Sciences (in press)

In this article, we explain the link between Pohlen's extended Hadamard product and the holomorphic cohomological convolution on C^*. For this purpose, we introduce a generalized Hadamard product, which ... [more ▼]

In this article, we explain the link between Pohlen's extended Hadamard product and the holomorphic cohomological convolution on C^*. For this purpose, we introduce a generalized Hadamard product, which is defined even if the holomorphic functions do not vanish at infinity, as well as a notion of strongly convolvable sets. [less ▲]

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See detailThe influence of interorganizational collaboration on logic conciliation and tensions within hybrid organizations: insights from social enterprise-corporate collaborations
Savarese, Claudia ULiege; Huybrechts, Benjamin ULiege; Hudon, Marek

in Journal of Business Ethics (in press)

An increasing amount of research has examined the management of competing logics, and possible tensions arising between them, within “hybrid organizations”. However, the ways in which the relationships of ... [more ▼]

An increasing amount of research has examined the management of competing logics, and possible tensions arising between them, within “hybrid organizations”. However, the ways in which the relationships of hybrids with other organizations shape the conciliation of these logics and tensions has received limited attention so far. In this theoretical paper, we examine how hybrid organizations deal with interorganizational collaboration, in particular whether and how their hybridity can be maintained when they partner with “dominant-logic organizations”. Drawing on empirical literature on social enterprise-corporate collaborations, we develop a framework and several propositions on how competing logics and their balancing within hybrid organizations may be affected by interactions with organizations underpinned by one dominant logic. We suggest that influences will mostly depend on the type of collaboration pursued. A collaboration based on a lower level of engagement and interaction between the two partners is likely to give precedence to one logic over the other, reducing inter-logic tensions but possibly compromising organizational hybridity. By contrast, a collaboration featuring numerous interactions and mission compatibility may facilitate sustained hybridity if tensions are acknowledged and managed. Our propositions contribute to the literatures on hybrid organizations, interorganizational collaboration, and social enterprise. [less ▲]

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See detailQUAND JE S’APPELLE OUBLI : DU SILENCE A L’ADRESSE, UNE POETIQUE DU CHAOS CHEZ LAURENT MAUVIGNIER
Vandormael, Thomas ULiege

in Kwartlanik neofilologiczny (in press)

This study aims to report on how the use of the allocutive person suggested by “Ce que j’appelle oubli”, eighth novel by Laurent Mauvignier, subsume many problematics that preside over the renewal of ... [more ▼]

This study aims to report on how the use of the allocutive person suggested by “Ce que j’appelle oubli”, eighth novel by Laurent Mauvignier, subsume many problematics that preside over the renewal of contemporary fictional forms such as the polyphony of narrative voices, the difficulty of placing an ‘I’ narrator confronted with the writing of society and particularly its minorities, as well as the place of silence within/in the literary text. [less ▲]

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See detailOccurrence of ‘gang of five’ Shiga toxin-producing Escherichia coli serogroups on Belgian dairy cattle farms by overshoe sampling
Engelen, Frederik; Thiry, Damien ULiege; Devleesschauwer, Brecht et al

in Letters in Applied Microbiology (in press), (702), 415-419

Significance and Impact of the Study: Shiga toxin-producing Escherichia coli (STEC) are important foodborne pathogens responsible for haemorrhagic colitis and haemolytic-uremic syndrome. Cattle are the ... [more ▼]

Significance and Impact of the Study: Shiga toxin-producing Escherichia coli (STEC) are important foodborne pathogens responsible for haemorrhagic colitis and haemolytic-uremic syndrome. Cattle are the major natural reservoir and excrete these bacteria in their faeces. This study investigated the occurrence and pathogenic potential of ‘gang of five’ STEC (O26, O103, O111, O145, O157) on Belgian dairy cattle farms and implemented a practical and animal-friendly sampling method aimed at promoting more widespread STEC surveillance in the bovine reservoir. Since these serogroups are most frequently implicated in human illness, more information on their presence in the bovine reservoir is required to develop efficient strategies aimed at reducing bovine carriage and the risk of human transmission. [less ▲]

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See detailRetrospective study of Diffuse Intrinsic Pontine Glioma in the Belgian population: a 25 year experience
Ruttens, D.; Messiaen, J.; Ferster, A. et al

in Journal of Neuro-Oncology (in press)

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See detailFigurines satiriques de singes en calcaire peint
Pietri, Renaud ULiege

in Bulletin archéologique des Écoles françaises à l'étranger (in press)

Report about a quick survey in Magasin 25 at Deir el-Medina which allowed to locate and gather a total of 27 painted limestonefigurines belonging to the same corpus, i. e. ‘figurines depicting monkeys ... [more ▼]

Report about a quick survey in Magasin 25 at Deir el-Medina which allowed to locate and gather a total of 27 painted limestonefigurines belonging to the same corpus, i. e. ‘figurines depicting monkeys imitating human activities’, such as playing music or driving a chariot. Most of those figurines are known thanks to Bernard Bruyère’s notebooks and publications. All of them have been documented in 2021. The 'monkeys driving chariots' subcorpus will be published in details in a future article. [less ▲]

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See detailNeural bases of inhibitory control: Combining transcranial magnetic stimulation and magnetic resonance imaging in alcohol-use disorder patients.
Quoilin, Caroline; Dricot, Laurence; Genon, Sarah ULiege et al

in NeuroImage (in press)

Inhibitory control underlies the ability to inhibit inappropriate responses and involves processes that suppress motor excitability. Such motor modulatory effect has been largely described during action ... [more ▼]

Inhibitory control underlies the ability to inhibit inappropriate responses and involves processes that suppress motor excitability. Such motor modulatory effect has been largely described during action preparation but very little is known about the neural circuit responsible for its implementation. Here, we addressed this point by studying the degree to which the extent of preparatory suppression relates to brain morphometry. We investigated this relationship in patients suffering from severe alcohol use disorder (AUD) because this population displays an inconsistent level of preparatory suppression and major structural brain damage, making it a suitable sample to measure such link. To do so, 45 detoxified patients underwent a structural magnetic resonance imaging (MRI) and performed a transcranial magnetic stimulation (TMS) experiment, in which the degree of preparatory suppression was quantified. Besides, behavioral inhibition and trait impulsivity were evaluated in all participants. Overall, whole-brain analyses revealed that a weaker preparatory suppression was associated with a decrease in cortical thickness of a medial prefrontal cluster, encompassing parts of the anterior cingulate cortex and superior-frontal gyrus. In addition, a negative association was observed between the thickness of the supplementary area (SMA)/pre-SMA and behavioral inhibition abilities. Finally, we did not find any significant correlation between preparatory suppression, behavioral inhibition and trait impulsivity, indicating that they represent different facets of inhibitory control. Altogether, the current study provides important insight on the neural regions underlying preparatory suppression and allows highlighting that the excitability of the motor system represents a valuable read-out of upstream cognitive processes. [less ▲]

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See detailMicromechanics-based material networks revisited from the interaction viewpoint; robust and e cient implementation for multi-phase composites
Nguyen, Van Dung ULiege; Noels, Ludovic ULiege

in European Journal of Mechanics. A, Solids (in press)

A material network consists of discrete material nodes, which, when interacting, can represent complex microstructure responses. In this work, we investigate this concept of material networks under the ... [more ▼]

A material network consists of discrete material nodes, which, when interacting, can represent complex microstructure responses. In this work, we investigate this concept of material networks under the viewpoint of the hierarchical network interactions. Within this viewpoint, the response of the material network is governed by a well-defined system of equations and an arbitrary number of phases can be considered, independently of the network architecture. The predictive capability is achieved by, on the one hand, sufficiently deep and rich network interactions to tie the discrete material nodes together, and, on the other hand, an efficient offline training procedure. For this purpose, a unified and efficient framework for an arbitrary network architecture is developed, not only for the offline training, but also for the online evaluation. The efficiency and prediction accuracy of the material network as a surrogate of a homogenization-based multiscale model in predicting the stress-strain response in both contexts of a virtual test and of FE2 multiscale simulations are demonstrated through numerical examples with two-phase and three-phase fiber-reinforced composites. [less ▲]

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See detailExperiencing the a priori
Seron, Denis ULiege

in European Journal of Philosophy (in press)

Brentano clearly asserts, in his Vienna lectures of 1887-8, that his descriptive psychology is an a priori or ‘exact’ science. Since he rejects Kant’s idea of a synthetic a priori, this means that the ... [more ▼]

Brentano clearly asserts, in his Vienna lectures of 1887-8, that his descriptive psychology is an a priori or ‘exact’ science. Since he rejects Kant’s idea of a synthetic a priori, this means that the descriptive psychologist’s laws are analytic. My aim in this paper is to clarify and discuss this view. I examine Brentano’s epistemology in the Psychology from an Empirical Standpoint and then its later developments. I conclude with a difficulty inherent in Brentano’s psychological approach to a priori knowledge. [less ▲]

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See detailAugmenting brand community identification for inactive users: a uses and gratification perspective
Dessart, Laurence ULiege; Veloutsou, Cleopatra

in Journal of Research in Interactive Marketing (in press)

In an era where companies shift a part of their marketing budget to support their social media presence, very little is known about the antecedents and effects of participant identification in a social ... [more ▼]

In an era where companies shift a part of their marketing budget to support their social media presence, very little is known about the antecedents and effects of participant identification in a social media community. This research aims to examine the antecedents of community identification in a Facebook company-managed brand community, for inactive members, using the Uses and Gratification Theory (UGT). Brand community identification is also expected to lead to higher levels of brand loyalty for these members. This research reports the results of a quantitative with survey data from 389 members of a variety of different official Facebook pages. The results reveal that inactive members of Facebook pages can be influenced to act in a way that is beneficial for a company. Perceived human and information value of the brand Facebook page lead members to identify with a brand community and identification is a strong predictor of loyalty to the brand. By showing that brand community identification and loyalty exists for users with low activity levels, this research challenges the widely accepted idea that only highly active members are valuable in online brand communities. Specifically, it reveals the most important motivations for these members to identify with the community and be loyal to the brand. [less ▲]

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