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See detailWinter season changes in Belgium: the MAR model contribution to the CORDEX.be project
Wyard, Coraline ULiege; Doutreloup, Sébastien ULiege; Scholzen, Chloé et al

Conference (2017, November 17)

In the framework of the CORDEX.be project funded by Belspo, most universities and research institutes of Belgium have worked together in order to gather existing and ongoing Belgian research activities in ... [more ▼]

In the framework of the CORDEX.be project funded by Belspo, most universities and research institutes of Belgium have worked together in order to gather existing and ongoing Belgian research activities in the domain of climate modelling to create a coherent scientific basis for future climate services in Belgium. The Laboratory of Climatology of the University of Liège has performed climate simulations using the regional climate model MAR (“Modèle Atmosphérique Régional” in French) at a resolution of 5 km over the period 1959-2014. This research aims to study the evolution of several variables computed by MAR during the winters of the last 50 years. Except in snow accumulation, results show no statistically significant trend in winter temperature or precipitation in Belgium. This results from the strong influence of natural large-scale/low-frequency oscillations in the atmospheric circulation in winter such as the North Atlantic Oscillation. [less ▲]

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See detailSnoring: Surgical Options beyond UPPP & Tonsillectomy
POIRRIER, Anne-Lise ULiege

Conference (2017, November 17)

Core Message. Bring the ENT surgeon on board. ENT evaluation is even more indicated for OSA patients than for simple snorers. Snoring treatment never saved a marriage. Options extend far beyond surgery ... [more ▼]

Core Message. Bring the ENT surgeon on board. ENT evaluation is even more indicated for OSA patients than for simple snorers. Snoring treatment never saved a marriage. Options extend far beyond surgery. In case of surgery, options expand far beyond UPPP. [less ▲]

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See detailPréjugés et stéréotypes autour du grand âge
Missotten, Pierre ULiege

Conference given outside the academic context (2017)

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See detailUsage des boîtiers de vote électronique et développement professionnel de l’enseignant-universitaire
Detroz, Pascal ULiege; Younes, Nathalie

Conference (2017, November 16)

Les boitiers de vote font l’objet de très nombreux articles. Les auteurs cherchent par exemple à voir si l’utilisation de cet outil a un effet sur la motivation des étudiants et leur participation au ... [more ▼]

Les boitiers de vote font l’objet de très nombreux articles. Les auteurs cherchent par exemple à voir si l’utilisation de cet outil a un effet sur la motivation des étudiants et leur participation au cours (Caldwell, 2007), sur leur engagement (Mc Gowan et Gunderson,2010), sur le climat de classe (Bain et Przybyla, 2009) ou encore sur les apprentissages qu’ils réalisent (Preszler et al., 2007). Au final, comme souvent lorsqu’il s’agit de technologie, il semble que ce soit la pédagogie supportée par l’outil qui fasse la différence : l’usage sera pertinent s’il entre en résonance et en concordance avec une pédagogie efficace. Certes, l’outil en lui-même peut avoir un effet sur la pédagogie. Influencer, de par son fonctionnement - les possibilités qu’il offre, parfois les contraintes qu’il fait peser - la manière de concevoir des dispositifs pédagogiques. Il peut ainsi modifier le rapport des enseignants à leur pédagogie, c’est-à-dire, finalement, stimuler ou catalyser le développement professionnel des enseignants dans le domaine de la pédagogie universitaire. L’effet de l’outil et de son usage sur ce développement professionnel est au cœur de notre article. En effet, nous avons greffé - sur deux dispositifs d’accompagnement technopédagogique d’enseignants novices dans le domaine des BVE - un dispositif de recherche observant l’effet de cet usage accompagné. L’un de ces dispositifs d’accompagnement était court : l’enseignant est interviewé à deux reprises et observé lors d’une séance de cours durant laquelle les BVE sont utilisés. L’autre est plus long et comprend des autoconfrontations, des interviews, le recueil de l’avis des étudiants… La méthodologie utilisée dans cette étude, de type qualitatif, confirme notre intuition de départ : l’usage accompagné de BVE chez des enseignants novices peut, sous certaines conditions dont nous ferons état lors de la communication, accélérer le développement professionnel de ces derniers. [less ▲]

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See detailPratiques d’évaluation des acquis, ancienneté et attitudes face à l’évaluation
Romainville, Marc; Detroz, Pascal ULiege; Auquière, Amélie ULiege et al

Conference (2017, November 16)

La présente communication est issue d’une recherche plus globale visant à identifier et à mieux comprendre les pratiques d’évaluation des acquis des étudiants auxquelles recourent les enseignants de ... [more ▼]

La présente communication est issue d’une recherche plus globale visant à identifier et à mieux comprendre les pratiques d’évaluation des acquis des étudiants auxquelles recourent les enseignants de l’enseignement supérieur et en particulier les facteurs personnels (ancienneté, attitudes vis-à-vis de l’évaluation…) et contextuels (année d’étude, taille du groupe, disciplines…) qui influencent ces pratiques. Les données ont été recueillies en 2016, d’une part, via une enquête en ligne (élaborée à l’aide du logiciel d’enquêtes Qualtrics) auprès d’enseignants de l’enseignement supérieur belge francophone que ce soit à l’Université ou en Hautes écoles (2292 réponses) et, d’autre part, via 37 entretiens semi-structurés individuels réalisés auprès d’un échantillon de ces mêmes enseignants dans des filières d’études contrastées. Les résultats présentés dans le cadre de cette communication ont trait à l’impact de deux variables personnelles : l’ancienneté des enseignants et leurs attitudes vis-à-vis de l’évaluation. Autrement dit, on cherchera à savoir si l’ancienneté et le développement professionnel qui l’accompagne traditionnellement ont des incidences sur le type de pratiques d’évaluation des acquis des enseignants. En particulier, recourent-ils à des outils de plus en plus diversifiés ou ont-ils tendance à se spécialiser dans l’un ou l’autre ? Et si oui, pourquoi ? Accentuent-ils par ailleurs le recours à l’évaluation continue par rapport au poids du contrôle terminal ? On cherchera ensuite à comprendre comment les pratiques se reconfigurent en fonction des attitudes des enseignants vis-à-vis de l’évaluation et en particulier vis-à-vis de sa fonction et de son rapport à l’apprentissage : dans quel sens une conception davantage intégrative de l’évaluation colore-t-elle les pratiques déclarées d’évaluation ? [less ▲]

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See detailCarte interactomique entre l'oncoprotéine Tax du virus HTLV-1 et les protéines à domaines PDZ.
Blibek, Karim ULiege

Doctoral thesis (2017)

HTLV-1 (Human T-cell Leukemia Virus) is the etiologic agent of human adult T-cell leukemia (ATL) and tropical spastic paraparesis (TSP). More than 20 million people worldwide are infected with the HTLV-1 ... [more ▼]

HTLV-1 (Human T-cell Leukemia Virus) is the etiologic agent of human adult T-cell leukemia (ATL) and tropical spastic paraparesis (TSP). More than 20 million people worldwide are infected with the HTLV-1 virus, but only about 5 % develop the associated pathologies. At present, efforts are invested in the search for treatments that may improve the survival expectancy of patients infected by the HTLV-1 virus. The diagnosis of HTLV-1 infection is hampered by the viral genome latency (up to 40 years) and treatment options are limited. To propose novel therapeutic opportunities, it thus is necessary to better understand the host molecular mechanisms perturbed by the HTLV-1 infection. The HTLV-1 genome encodes for the Tax-1 protein, which confers the transforming ability of the virus. The Tax-1 protein is known as the transactivator factor of the HTLV-1 virus genome expression (TransActivator of pX region). It is also involved in the destabilization of several molecular mechanisms within the host, leading to cellular transformation. Tax-1 protein displays several functional domains and interacts with a wide range of cellular proteins. In particular, the Tax-1 protein sequence contains, at its carboxy-terminal end, a motif of four amino acids able to interact with PDZ domain (PSD95-DLG1-ZO1) containing proteins. It has been demonstrated that deletion of the PDZ binding motif (PBM) of the Tax-1 protein leads to a decrease of its oncogenic capacity in vitro. Cellular proteins containing PDZ domains are involved in the formation of cellular junctions, synapses and in cellular receptors assembly. Some of PDZ proteins are capable of relaying extracellular signals and participate in the control of proliferation. The human genome codes for at least 150 proteins with PDZ domains. However, the specificity of the oncoprotein Tax-1 to target these proteins remains unknown. In this study, we have mapped The Tax-1 - PDZ interactome using a combination of several methods. We reveal that Tax-1 selectively target a number of PDZ domains-containing proteins potentially involved in HTLV-1 pathogenesis. We validated our approach by focusing on the role of SDCBP and LNX2 proteins in HTLV-1 biology. Our work also demonstrated that the Tax-1-PDZ interactome might represent an attractive therapeutic target for HTLV-1-induced diseases. [less ▲]

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See detailJacqueline Harpman, Le Bonheur dans le crime
Outers, Pierre ULiege

Conference given outside the academic context (2017)

Detailed reference viewed: 18 (1 ULiège)
See detailDwelling on Dwelling: Home and Nature in (Native) American Literature
Lombard, David ULiege

Conference (2017, November 16)

As Greg Garrard stresses, “[i]nterpretation and critique of the various inflections of dwelling is a major task for ecocritics interested in a predominantly political, rather than moral or spiritual ... [more ▼]

As Greg Garrard stresses, “[i]nterpretation and critique of the various inflections of dwelling is a major task for ecocritics interested in a predominantly political, rather than moral or spiritual, project of cultural critique that can take us beyond pastoral and nature writing, from the landscapes of leisure to the uneven terrain of real work” (2012). In this paper, I will examine American literary texts dealing with representations of dwelling or “home” as a refuge from the “tensions” or problems caused by modern civilisation and technology. Starting with Thoreau’s Walden (1854), I will focus on the relationships between such refuges, the natural environment, and socio-political critique. Indeed, Thoreau’s work displays a philosophy on nature and dwelling that has influenced other writers to ponder on the negative effects that modern technologies, capitalism and consumerism have had on the human self and, more largely, on our physical environment. Adopting an ecocritical perspective, I will therefore consider Thoreau’s stay in Walden Pond as well as Edward Abbey’s house trailer (Desert Solitaire, 1968), Christopher McCandless’s “magic bus” as depicted in Jon Krakauer’s Into the Wild (1992) or Ken Ilgunas’s “vandwelling” (Walden on Wheels, 2013) to study the socio-political and environmental concerns raised by dwelling experiences in such peculiar or isolated “homes”. Finally, I will also briefly discuss the Native American perspective through an analysis of Leslie Marmon Silko’s novel Ceremony (1977) as an example of the Laguna Pueblo’s perception of nature or the “land” as “home”. [less ▲]

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See detailUn autre regard sur la participation des écoles et des élèves à l’enquête du PISA
Raiche, Gilles; Béland, Sébastien; Magis, David ULiege

Conference (2017, November 16)

Le Programme international pour le suivi des acquis des élèves (PISA) a pour objectif de produire des indicateurs sur les habiletés et les connaissances qui contribuent au succès des élèves, des écoles ... [more ▼]

Le Programme international pour le suivi des acquis des élèves (PISA) a pour objectif de produire des indicateurs sur les habiletés et les connaissances qui contribuent au succès des élèves, des écoles, des systèmes éducatifs et des environnements d’apprentissage (CMEC, 2015, p. 7). Depuis 2000, l’enquête du PISA est planifiée à tous les trois ans pour les élèves de 15 ans en ciblant spécifiquement les matières suivantes : la compréhension de l’écrit, la culture mathématique et la culture scientifique. Dans le cadre de la dernière passation, les résultats des Canadiens à cette enquête ont été salués dans l’ensemble du pays : les élèves se classent dans le groupe des pays les plus performants pour toutes les disciplines couvertes. Par contre, le taux de participation des écoles ainsi que les taux d’exclusions des élèves au regard de divers handicaps, qui pourraient éventuellement avoir un impact sur les résultats et le classement international, ont été critiqués à travers le pays. Cette présentation a comme objectif d’étudier le rendement des élèves canadiens au programme international des acquis scolaires (PISA) entre 2000 à 2015 en fonction de différentes caractéristiques relatives à la participation des écoles et au taux d’exclusion des élèves présentant certains handicaps. Des modèles de régression linéaire à niveaux multiples sont utilisés à cette fin. [less ▲]

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See detailCarte interactomique entre l'oncoprotéine Tax du virus HTLV-1 et les protéines à domaines PDZ.
Blibek, Karim ULiege

Scientific conference (2017, November 16)

ABSTRACT HTLV-1 (Human T-cell Leukemia Virus) is the etiologic agent of human adult T-cell leukemia (ATL) and tropical spastic paraparesis (TSP). More than 20 million people worldwide are infected with ... [more ▼]

ABSTRACT HTLV-1 (Human T-cell Leukemia Virus) is the etiologic agent of human adult T-cell leukemia (ATL) and tropical spastic paraparesis (TSP). More than 20 million people worldwide are infected with the HTLV-1 virus, but only about 5 % develop the associated pathologies. At present, efforts are invested in the search for treatments that may improve the survival expectancy of patients infected by the HTLV-1 virus. The diagnosis of HTLV-1 infection is hampered by the viral genome latency (up to 40 years) and treatment options are limited. To propose novel therapeutic opportunities, it thus is necessary to better understand the host molecular mechanisms perturbed by the HTLV-1 infection. The HTLV-1 genome encodes for the Tax-1 protein, which confers the transforming ability of the virus. The Tax-1 protein is known as the transactivator factor of the HTLV-1 virus genome expression (TransActivator of pX region). It is also involved in the destabilization of several molecular mechanisms within the host, leading to cellular transformation. Tax-1 protein displays several functional domains and interacts with a wide range of cellular proteins. In particular, the Tax-1 protein sequence contains, at its carboxy-terminal end, a motif of four amino acids able to interact with PDZ domain (PSD95-DLG1-ZO1) containing proteins. It has been demonstrated that deletion of the PDZ binding motif (PBM) of the Tax-1 protein leads to a decrease of its oncogenic capacity in vitro. Cellular proteins containing PDZ domains are involved in the formation of cellular junctions, synapses and in cellular receptors assembly. Some of PDZ proteins are capable of relaying extracellular signals and participate in the control of proliferation. The human genome codes for at least 150 proteins with PDZ domains. However, the specificity of the oncoprotein Tax-1 to target these proteins remains unknown. In this study, we have mapped The Tax-1 - PDZ interactome using a combination of several methods. We reveal that Tax-1 selectively target a number of PDZ domains-containing proteins potentially involved in HTLV-1 pathogenesis. We validated our approach by focusing on the role of SDCBP and LNX2 proteins in HTLV-1 biology. Our work also demonstrated that the Tax-1-PDZ interactome might represent an attractive therapeutic target for HTLV-1-induced diseases. KEYWORDS: HTLV-1, Leukemia, Tax-1, interactions, PDZ. [less ▲]

Detailed reference viewed: 14 (1 ULiège)
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See detailReforming of toluene with bimetallic catalysts supported on alumina and synthesized by an aqueous sol-gel process
Lambert, Stéphanie ULiege

Conference (2017, November 16)

The thermochemical method called “biomass gasification” is generating emphatic interest for the production of bio-Syngas (CO+H2) since this process presents the advantage of being renewable without ... [more ▼]

The thermochemical method called “biomass gasification” is generating emphatic interest for the production of bio-Syngas (CO+H2) since this process presents the advantage of being renewable without emitting CO2. However, in practical applications, there are still some technical problems due to high concentration of tars in the outlet gas, which can condensate and clog the pipes. Previous studies have highlighted the fact that the tar elimination via catalytic reforming seem to be the more practical and economical solution. Catalysts were synthesized by an aqueous sol-gel process to develop γ-Al2O3 doped with 10wt.% of nickel and 2 wt.% of a second dopant (Co, Cu, Fe, Mn, Mo). [less ▲]

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See detailSteering social fields of mobilization in global cities: Latin American transnational political engagement in Brussels
Lara Guerrero, Larisa Viridiana ULiege; Vivas Romero, Maria ULiege

Conference (2017, November 15)

Social scientists and migration scholars have a growing interest in how and why migrants engage in transnational political movements in both their home and host countries. Migrants are active agents ... [more ▼]

Social scientists and migration scholars have a growing interest in how and why migrants engage in transnational political movements in both their home and host countries. Migrants are active agents participating in transnational social movements. They create, transform, and exploit transnational networks to engage in political movements in their homeland and in their hostland from cities. This chapter aims to answer the following questions: how do global cities shape transnational fields of social mobilization? What is the nexus between these transnational fields of social mobilization and access to welfare states? Theoretically, this contribution introduces a new spatial level of analysis to unpack the dynamics and dimensions of migrant social movements organized in global cities. By focusing specifically on the city of Brussels, this contribution analyzes the impact of global cities shaping the capacity and desire of Latin American migrants in engaging in political movements. Empirically, this chapter presents two case studies where Latin Americans living in Brussels engage in political transnational activities to change their living conditions both in their host and home cities. These examples illustrate the role of migrants influencing and shaping welfare-state and political systems in both their sending and receiving societies. [less ▲]

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See detailL'Europe est-elle plus verte ?
Habran, Maxime ULiege

Conference given outside the academic context (2017)

Bilan de la politique environnementale et de la lutte contre le changement climatique au sein des politiques européennes

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See detailOverview and future challenges of nearly Zero Energy Buildings (nZEB) design in Southern Europe
Attia, Shady ULiege; Polyvios, Eleftheriou; Xeni, Flouris et al

in Energy and Buildings (2017), 155

In times of great transition of the European construction sector to energy efficient and nearly zero energy buildings (nZEB), a market observation containing qualitative and quantitative indications ... [more ▼]

In times of great transition of the European construction sector to energy efficient and nearly zero energy buildings (nZEB), a market observation containing qualitative and quantitative indications should help to fill out some of the current gaps concerning the EU 2020 carbon targets. Next to the economic challenges, there are equally important factors that hinder renovating the existing residential building stock and adding newly constructed high performance buildings. Under these circumstances this paper summarises the findings of a cross-comparative study of the societal and technical barriers of nZEB implementation in 7 Southern European countries. The study analyses the present situation and provides an overview on future prospects for nZEB in Southern Europe. The result presents an overview of challenges and provides recommendations based on available empirical evidence to further lower those barriers in the European construction sector. The paper finds that the most Southern European countries are poorly prepared for nZEB implementation and especially to the challenge/opportunity of retrofitting existing buildings. Creating a common approach to further develop nZEB targets, concepts and definitions in synergy with the climatic, societal and technical state of progress in Southern Europe is essential. The paper provides recommendations for actions to shift the identified gaps into opportunities for future development of climate adaptive high performance buildings. [less ▲]

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See detailCaractérisation ontogénique, phénotypique et fonctionnelle des macrophages interstitiels pulmonaires après exposition à des composés bactériens
Sabatel, Catherine ULiege

Doctoral thesis (2017)

Respiratory mucosal surfaces are continuously exposed to harmless antigens and immunostimulatory molecules of microbial origin. According to the « self/non self » and « danger » theories, this should ... [more ▼]

Respiratory mucosal surfaces are continuously exposed to harmless antigens and immunostimulatory molecules of microbial origin. According to the « self/non self » and « danger » theories, this should normally result in the developpment of unwanted immune responses towards these inhaled antigens such as Th2-mediated allergic responses. This is however not the case in most people. The hygiene hypothesis postulates that living in an environment rich in microbial components paradoxically protects from airway allergy, implying the existence in the lung of suppressive mechanisms triggered by these immunogenic signals. In this study, we showed that synthetic bacterial DNA rich in unmethylated CpG motifs (CpG) has the unique ability to significantly increase the population of lung interstitial regulatory macrophages (IM) from CCR2-independent monocytes residing in the lung or mobilized from the spleen. Moreover these CpG-induced IM demonstrated a hypersuppressive profile as they produced more IL-10 than their steady state counterparts. Using mice models of airway allergy we showed that the transfert of IM isolated from CpG-treated mice recapitulated the protective effects of CpG when administered before allergen sensitization or challenge. This IM-mediated protection was dependant from IL-10 as CpG-induced Il10-/- IM had no protective effect. The expansion of pulmonary regulatory IM from CCR2-independent pulmonary and splenic monocytes upon CpG exposure could be a possible mechanism by which exposure to an environment rich in microbial products protects against asthma. [less ▲]

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See detailAnomalies des gonadotrophines LH et FSH: tableaux cliniques
VALDES SOCIN, Hernan Gonzalo ULiege

Scientific conference (2017, November 14)

L’hormone lutéinisante (LH) et l’hormone folliculostimulante (FSH) – hormones glycoprotéiques hypophysaires – régulent de concert la production de stéroïdes sexuels et la reproduction. Les stéroïdes ... [more ▼]

L’hormone lutéinisante (LH) et l’hormone folliculostimulante (FSH) – hormones glycoprotéiques hypophysaires – régulent de concert la production de stéroïdes sexuels et la reproduction. Les stéroïdes sexuels sont indispensables à la virilisation et à la féminisation, et participent également à la gamétogenèse (spermatogenèse chez l’homme et folliculogenèse chez la femme). Cette présentation fait le point sur la physiologie et la pathologie de LH et de FSH en reproduction humaine. [less ▲]

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See detailQuels futurs pour la fabrication de pièces métalliques ?
Habraken, Anne ULiege; Delvenne, Pierre ULiege; Elsen, Catherine ULiege

Conference given outside the academic context (2017)

Les processus de fabrication des pièces métalliques sont au cœur de nombreux enjeux technologiques, sociopolitiques et économiques. Ces dernières années, des procédés tels le 3D Printing ou encore le ... [more ▼]

Les processus de fabrication des pièces métalliques sont au cœur de nombreux enjeux technologiques, sociopolitiques et économiques. Ces dernières années, des procédés tels le 3D Printing ou encore le formage incrémental ont apporté un renouveau possible face aux méthodes de fabrication traditionnelles. Si le premier est, à présent, bien connu du grand public, le formage incrémental mérite encore quelques explications. Ce procédé, relativement lent, est de mieux en mieux maîtrisé. Il permet de réaliser des pièces métalliques aussi diverses qu’une prothèse, un panneau de façade ou de porte de boeing, un évier de cuisine, ... Il comporte de multiples variantes et est progressivement exploité par l’industrie pour du prototypage de pièces uniques et des petites séries. A l’ère de la révolution numérique, où les Fablabs, Repair Cafés et autres Hackers Labs permettent aux citoyens de créer leurs propres pièces et de devenir acteurs de l’innovation, ce procédé ouvre ainsi de nouvelles portes pour la conception de pièces métalliques. [less ▲]

Detailed reference viewed: 31 (2 ULiège)