Dumoulin, M., Morales Yánez, F. J., Redeghieri, P., Vanbever, R., Vanderstraeten, J., Leal, T., Mottais, A., Muyldermans, S., & Vincke, C. (02 January 2025). Single-domain antibody for the inhibition of neutrophil elastase activity. |
![]() ![]() | Redeghieri, P., Moray, J., Kerff, F., Gohy, S., Leal, T., Muyldermans, S., Vanbever, R., Morales Yánez, F. J.* , & Dumoulin, M.*. (27 November 2024). Enzymatic, structural, and biophysical characterization of a single-domain antibody (VHH) selectively and tightly inhibiting neutrophil elastase and exhibiting favorable developability properties. Protein Science: A Publication of the Protein Society, 33 (12), 5227. doi:10.1002/pro.5227 ![]() * These authors have contributed equally to this work. |
Redeghieri, P., Moray, J., Kerff, F., Mottais, A., Leal, T., Gohy, S., Muylderman, S., Morales Yánez, F. J., & Dumoulin, M. (15 November 2024). NbE201: a single-domain antibody fragment to inhibit neutrophil elastase and reduce inflammation [Paper presentation]. SFMBBM - PhD Day 2024 (UNamur), Namur, Belgium. |
Morales-Yánez, F. J., Cawez, F., Redeghieri, P., Moray, J., Vincke, C., Struelens, G., Leal, T., Vanbever, R., Vanderplasschen, A., Muyldermans, S., Galleni, M., & Dumoulin, M. (16 September 2024). DIRECTIONAL SANDWICH PANNING IN SOLUTION TO SELECT INHIBITORY NANO-ANTIBODIES AGAINST FRAGILE ENZYMES INCLUDING PROTEASES [Paper presentation]. FASEB 2024 Advanced Course, Proteolysis: at the interface between health and disease, Bled, Slovenia. |
Redeghieri, P., Moray, J., Kerff, F., Mottais, A., Vincke, C., Leal, T., Gohy, S., Morales Yánez, F. J.* , & Dumoulin, M.*. (16 September 2024). NbE201: a Single-Domain Antibody fragment to Inhibit Neutrophil Elastase and reduce inflammation [Paper presentation]. FEBS Wokshop 2024, Proteolysis: at the interface between health and disease, Bled, Slovenia. * These authors have contributed equally to this work. |
Redeghieri, P., Moray, J., Kerff, F., Mottais, A., Vandersraeten, J., Vincke, C., Leal, T., Gohy, S., Muylderman, S., Vanbever, R., Morales-Yánez, F. J.* , & Dumoulin, M.*. (13 June 2024). A Single-Domain Antibody Fragment (VHH) Inhibiting Neutrophil Elastase for the Treatment of Inflammatory Lung Diseases [Paper presentation]. Proteolytic Enzymes and Their Inhibitors, Gordon Research Conference, Lucca, Italy. * These authors have contributed equally to this work. |
Redeghieri, P., Moray, J., Kerff, F., Mottais, A., Vandersraeten, J., Vincke, C., Leal, T., Gohy, S., Muylderman, S., Vanbever, R., Morales Yánez, F. J.* , & Dumoulin, M.*. (09 June 2024). A Single-Domain Antibody Fragment (VHH) Inhibiting Neutrophil Elastase for the Treatment of Inflammatory Lung Diseases [Poster presentation]. Proteolytic Enzymes and Their Inhibitors (GRS) Gordon Research Seminar. * These authors have contributed equally to this work. |
Redeghieri, P., Moray, J., Kerff, F., Leal, T., Muyldermans, S., Vanbever, R., Morales Yánez, F. J.* , & Dumoulin, M.*. (30 May 2024). ENZYMATIC, STRUCTURAL AND BIOPHYSICAL CHARACTERIZATION OF A SINGLE DOMAIN ANTIBODY (VHH) SELECTIVELY AND TIGHTLY INHIBITING NEUTROPHIL ELASTASE AND EXHIBITING FAVORABLE DEVELOPABILITY PROPERTIES [Paper presentation]. Interuniversity PhD Student Day, Louvain-la-Neuve, Belgium. * These authors have contributed equally to this work. |
Redeghieri, P., Moray, J., Kerff, F., Mottais, A., Vanderstraeten, J., Vincke, C., Leal, T., Gohy, S., Muylderman, S., Vanbever, R., Morales Yánez, F. J.* , & Dumoulin, M.*. (23 May 2024). A single-domain antibody fragment (VHH) inhibiting neutrophil elastase for the treatment of inflammatory lung diseases [Paper presentation]. InBioS DAY, Liège, Belgium. * These authors have contributed equally to this work. |
Redeghieri, P., Moray, J., Kerff, F., Vincke, C., Leal, T., Muyldermans, S., Vanbever, R., Morales Yánez, F. J., & Dumoulin, M. (18 September 2023). In vitro characterisation of a Nanobody selectively inhibiting human Neutrophil elastase [Poster presentation]. Single domain antibodies conference 2023, Paris, France. |
Redeghieri, P., Vanbever, R., & Dumoulin, M. (15 June 2022). Nanobodies as therapeutic nanomedicines for lungs inflammatory diseases [Paper presentation]. 5th InBios Day, Liège, Belgium. |