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Redeghieri Paola

Faculté des Sciences > Doct. scienc. (bioch. biol. moléc. cell. bioinf. mod.

ORCID
0009-0008-1527-5871
Main Referenced Co-authors
Dumoulin, Mireille  (12)
Leal, Teresinha (9)
Moray, Joël  (9)
Vanbever, Rita (9)
Kerff, Frédéric  (8)
Main Referenced Keywords
VHHs (2); alpha 1-Antitrypsin (1); alpha 1-Antitrypsin/chemistry (1); alpha 1-Antitrypsin/metabolism (1); Animals (1);
Main Referenced Unit & Research Centers
CIP - Centre d'Ingénierie des Protéines - ULiège (1)
Main Referenced Disciplines
Biochemistry, biophysics & molecular biology (12)
Human health sciences: Multidisciplinary, general & others (1)

Publications (total 13)

The most downloaded
3 downloads
Redeghieri, P., Moray, J., Kerff, F., Gohy, S., Leal, T., Muyldermans, S., Vanbever, R., Morales Yánez, F. J.* , & Dumoulin, M.*. (27 November 2024). Enzymatic, structural, and biophysical characterization of a single-domain antibody (VHH) selectively and tightly inhibiting neutrophil elastase and exhibiting favorable developability properties. Protein Science: A Publication of the Protein Society, 33 (12), 5227. doi:10.1002/pro.5227 https://hdl.handle.net/2268/324975

Redeghieri, P. (2025). Camelid single domain antibodies inhibiting neutrophil serine proteases as therapeutic and prognostic agents in the context of inflammatory diseases [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/335746

Dumoulin, M., Morales Yánez, F. J., Redeghieri, P., Vanbever, R., Vanderstraeten, J., Leal, T., Mottais, A., Muyldermans, S., & Vincke, C. (02 January 2025). Single-domain antibody for the inhibition of neutrophil elastase activity.

Redeghieri, P., Moray, J., Kerff, F., Gohy, S., Leal, T., Muyldermans, S., Vanbever, R., Morales Yánez, F. J.* , & Dumoulin, M.*. (27 November 2024). Enzymatic, structural, and biophysical characterization of a single-domain antibody (VHH) selectively and tightly inhibiting neutrophil elastase and exhibiting favorable developability properties. Protein Science: A Publication of the Protein Society, 33 (12), 5227. doi:10.1002/pro.5227
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Redeghieri, P., Moray, J., Kerff, F., Mottais, A., Leal, T., Gohy, S., Muylderman, S., Morales Yánez, F. J., & Dumoulin, M. (15 November 2024). NbE201: a single-domain antibody fragment to inhibit neutrophil elastase and reduce inflammation [Paper presentation]. SFMBBM - PhD Day 2024 (UNamur), Namur, Belgium.

Morales-Yánez, F. J., Cawez, F., Redeghieri, P., Moray, J., Vincke, C., Struelens, G., Leal, T., Vanbever, R., Vanderplasschen, A., Muyldermans, S., Galleni, M., & Dumoulin, M. (16 September 2024). DIRECTIONAL SANDWICH PANNING IN SOLUTION TO SELECT INHIBITORY NANO-ANTIBODIES AGAINST FRAGILE ENZYMES INCLUDING PROTEASES [Paper presentation]. FASEB 2024 Advanced Course, Proteolysis: at the interface between health and disease, Bled, Slovenia.

Redeghieri, P., Moray, J., Kerff, F., Mottais, A., Vincke, C., Leal, T., Gohy, S., Morales Yánez, F. J.* , & Dumoulin, M.*. (16 September 2024). NbE201: a Single-Domain Antibody fragment to Inhibit Neutrophil Elastase and reduce inflammation [Paper presentation]. FEBS Wokshop 2024, Proteolysis: at the interface between health and disease, Bled, Slovenia.
* These authors have contributed equally to this work.

Redeghieri, P., Moray, J., Kerff, F., Mottais, A., Vandersraeten, J., Vincke, C., Leal, T., Gohy, S., Muylderman, S., Vanbever, R., Morales-Yánez, F. J.* , & Dumoulin, M.*. (13 June 2024). A Single-Domain Antibody Fragment (VHH) Inhibiting Neutrophil Elastase for the Treatment of Inflammatory Lung Diseases​ [Paper presentation]. Proteolytic Enzymes and Their Inhibitors, Gordon Research Conference, Lucca, Italy.
* These authors have contributed equally to this work.

Redeghieri, P., Moray, J., Kerff, F., Mottais, A., Vandersraeten, J., Vincke, C., Leal, T., Gohy, S., Muylderman, S., Vanbever, R., Morales Yánez, F. J.* , & Dumoulin, M.*. (09 June 2024). A Single-Domain Antibody Fragment (VHH) Inhibiting Neutrophil Elastase for the Treatment of Inflammatory Lung Diseases [Poster presentation]. Proteolytic Enzymes and Their Inhibitors (GRS) Gordon Research Seminar.
* These authors have contributed equally to this work.

Redeghieri, P., Moray, J., Kerff, F., Leal, T., Muyldermans, S., Vanbever, R., Morales Yánez, F. J.* , & Dumoulin, M.*. (30 May 2024). ENZYMATIC, STRUCTURAL AND BIOPHYSICAL CHARACTERIZATION OF A SINGLE DOMAIN ANTIBODY (VHH) SELECTIVELY AND TIGHTLY INHIBITING NEUTROPHIL ELASTASE AND EXHIBITING FAVORABLE DEVELOPABILITY PROPERTIES [Paper presentation]. Interuniversity PhD Student Day, Louvain-la-Neuve, Belgium.
* These authors have contributed equally to this work.

Redeghieri, P., Moray, J., Kerff, F., Mottais, A., Vanderstraeten, J., Vincke, C., Leal, T., Gohy, S., Muylderman, S., Vanbever, R., Morales Yánez, F. J.* , & Dumoulin, M.*. (23 May 2024). A single-domain antibody fragment (VHH) inhibiting neutrophil elastase for the treatment of inflammatory lung diseases [Paper presentation]. InBioS DAY, Liège, Belgium.
* These authors have contributed equally to this work.

Redeghieri, P., Moray, J., Kerff, F., Vincke, C., Leal, T., Muyldermans, S., Vanbever, R., Morales Yánez, F. J., & Dumoulin, M. (18 September 2023). In vitro characterisation of a Nanobody selectively inhibiting human Neutrophil elastase [Poster presentation]. Single domain antibodies conference 2023, Paris, France.

Morbidelli, M., Cataldo, D., Lassaux, P., Dumoulin, M., & Redeghieri, P. (18 September 2023). Characterization of a nanobody against mesothelin: a new way to defeat Mesothelioma [Poster presentation]. Single-Domain Antibodies 2023, Paris, France.

Redeghieri, P., Vanbever, R., & Dumoulin, M. (15 June 2022). Nanobodies as therapeutic nanomedicines for lungs inflammatory diseases [Paper presentation]. 5th InBios Day, Liège, Belgium.

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