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Abboud Dayana

Département de pharmacie

Département de pharmacie > GIGA Molecular Biology of Diseases - Molecular Pharmacology

Voir les coordonnées de l'auteur
ORCID
0000-0003-4176-0631
Principaux co-auteurs référencés
Hanson, Julien  (33)
Pirotte, Bernard  (24)
Beckers, Albert  (23)
Daly, Adrian  (23)
Frossard, Nelly (16)
Principaux mots-clés référencés
GPR101 (3); Animals (2); beta-Arrestin 2 (2); beta-Arrestin 2/metabolism (2); beta-Arrestins (2);
Principaux centres et unités de recherche référencés
CIRM - Centre Interdisciplinaire de Recherche sur le Médicament - ULiège [BE] (1)
GIGA - molecular biology of disease (1)
GIGA Molecular Biology of Diseases - ULiège [BE] (1)
Principales disciplines référencées
Biochimie, biophysique & biologie moléculaire (22)
Pharmacie, pharmacologie & toxicologie (21)
Endocrinologie, métabolisme & nutrition (13)
Dermatologie (3)
Anatomie (cytologie, histologie, embryologie...) & physiologie (1)

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Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (21 September 2020). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Nature Communications, 11 (1), 4752. doi:10.1038/s41467-020-18500-x https://hdl.handle.net/2268/251225

La plus citée

62 citations (Scopus®)

Reynders, N., Abboud, D., Baragli, A., Noman, M. Z., Rogister, B., Niclou, S., Heveker, N., Janji, B., Hanson, J., Szpakowska, M., & Chevigné, A. (18 June 2019). The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment. Cells, 8 (6). https://hdl.handle.net/2268/238128

Caruso, M., Mazzatenta, D., Asioli, S., Costanza, G., Trivellin, G., Franke, M., Abboud, D., Hanson, J., Veronique Raverot, Pétrossians, P., Beckers, A., Cappa, M., & Daly, A. (2024). Case report: Management of pediatric gigantism caused by the TADopathy, X-linked acrogigantism. Frontiers in Endocrinology, 1-9. doi:10.3389/fendo.2024.1345363
Peer reviewed vérifié par ORBi

Abboud, D., Abboud, C., Inoue, A., Twizere, J.-C., & Hanson, J. (February 2024). Basal interaction of the orphan receptor GPR101 with arrestins leads to constitutive internalization. Biochemical Pharmacology, 220, 116013. doi:10.1016/j.bcp.2023.116013
Peer reviewed vérifié par ORBi

Pillaiyar, T., Wozniak, M., Abboud, D., Rasch, A., Liebing, A.-D., Poso, A., Kronenberger, T., Stäubert, C., Laufer, S. A., & Hanson, J. (28 December 2023). Development of Ligands for the Super Conserved Orphan G Protein-Coupled Receptor GPR27 with Improved Efficacy and Potency. Journal of Medicinal Chemistry, 66 (24), 17118 - 17137. doi:10.1021/acs.jmedchem.3c02030
Peer reviewed vérifié par ORBi

Goffin, E., Fraikin, P., Abboud, D., De Tullio, P., Beaufour, C., Botez, I., Hanson, J., Danober, L., Francotte, P., & Pirotte, B. (15 March 2023). New insights in the development of positive allosteric modulators of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors belonging to 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides: Introduction of (mono/difluoro)methyl groups at the 2-position of the thiadiazine ring. European Journal of Medicinal Chemistry, 250, 115221. doi:10.1016/j.ejmech.2023.115221
Peer reviewed vérifié par ORBi

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (April 2022). Deciphering the role of the GPR101 orphan receptor in growth hormone hypersecretion [Poster presentation]. Keystone Symposia Conference, GPCRs: An Odyssey from Structure, Signaling and Regulation to Therapeutics, Snowbird, United States.

Franke, M.* , Daly, A.* , Gonon Rodrigues Palmeira, L., Tirosh, A., Stigliano, A., Trifan, E., Faucz, F. R., Abboud, D., PETROSSIANS, P., Tena, J. J., Vitali, E., Lania, A. G., Gómez-Skarmeta, J. L., BECKERS, A.* , Stratakis, C. A.* , & Trivellin, G.*. (2022). Duplications disrupt chromatin architecture and rewire GPR101-enhancer communication in X-linked acrogigantism. American Journal of Human Genetics. doi:10.1016/j.ajhg.2022.02.002
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* Ces auteurs ont contribué de façon équivalente à la publication.

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (February 2022). Deciphering the role of the GPR101 orphan receptor in growth hormone hypersecretion [Paper presentation]. CIRM day, Liege, Belgium.

D'Uonnolo, G., Reynders, N., Meyrath, M., Abboud, D., Uchański, T., Laeremans, T., Volkman, B. F., Janji, B., Hanson, J., Szpakowska, M., & Chevigné, A. (2022). The Extended N-Terminal Domain Confers Atypical Chemokine Receptor Properties to CXCR3-B. Frontiers in Immunology, 13, 868579. doi:10.3389/fimmu.2022.868579
Peer reviewed vérifié par ORBi

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (October 2021). Deciphering the role of the GPR101 orphan receptor in growth hormone hypersecretion [Poster presentation]. 5th ERNEST meeting, Bari, Italy.

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (July 2021). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11 [Poster presentation]. 1st Transatlantic ECI GPCR symposium.

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (May 2021). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11 [Paper presentation]. FASEB, The Growth Hormone (GH)/ Prolactin (PRL) Family in Biology & Disease Conference.

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (April 2021). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11 [Paper presentation]. 4th ERNEST meeting.

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (April 2021). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11 [Paper presentation]. Belgian Society of Physiology and Pharmacology.

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (April 2021). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11 [Poster presentation]. American Society for Pharmacology and Experimental Therapeutics (ASPET), GPCR colloquium.

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (November 2020). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11 [Paper presentation]. GDR3545.

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., Beckers, A., & Hanson, J. (21 September 2020). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Nature Communications, 11 (1), 4752. doi:10.1038/s41467-020-18500-x
Peer reviewed vérifié par ORBi

Abboud, D., Daly, A., Dupuis, N., Bahri, M. A., Inoue, A., Chevigné, A., Ectors, F., Plenevaux, A., Pirotte, B., BECKERS, A., & Hanson, J. (2020). GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11 [Paper presentation]. 9TH GDR3545 GPCR INTERNATIONAL MEETING.

Abboud, D., Daly, A., Dupuis, N., Pirotte, B., BECKERS, A., & Hanson, J. (December 2019). GPR101 orphan receptor in XLAG syndrome [Paper presentation]. CIRM day.

Abboud, D., Daly, A., Dupuis, N., Pirotte, B., BECKERS, A., & Hanson, J. (July 2019). Pharmacology of GPR101 orphan receptor [Paper presentation]. Transardennaise de l’hypophyse.

Reynders, N., Abboud, D., Baragli, A., Noman, M. Z., Rogister, B., Niclou, S., Heveker, N., Janji, B., Hanson, J., Szpakowska, M., & Chevigné, A. (18 June 2019). The Distinct Roles of CXCR3 Variants and Their Ligands in the Tumor Microenvironment. Cells, 8 (6).
Peer reviewed vérifié par ORBi

Abboud, D., Daly, A., Dupuis, N., Pirotte, B., BECKERS, A., & Hanson, J. (May 2019). GPR101 orphan receptor in XLAG syndrome [Paper presentation]. Belgian Society of Physiology and Pharmacology.

Vandevoorde, S., Abboud, D., Laschet, C., Daly, A., Hanson, J., & Beckers, A. (May 2019). SOMATOSTATIN ANALOGUE RESISTANCE IN X-LAG SYNDROME - IDENTIFICATION OF THE UNDERLYING MECHANISMS [Poster presentation]. Spring meeting 2019 Belgian Society of Physiology and Pharmacology, Bruxelles, Belgium.

Abboud, D., Daly, A., Dupuis, N., Pirotte, B., BECKERS, A., & Hanson, J. (December 2018). GPR101 orphan receptor in XLAG syndrome [Paper presentation]. CIRM day.

Regenass, P., Abboud, D., Daubeuf, F., Lehalle, C., Gizzi, P., Riché, S., Hachet-Haas, M., Rohmer, F., Gasparik, V., Boeglin, D., Haeich, J., Knehans, T., Rognan, D., Heissler, D., Marsol, C., Villa, P., Galzi, J.-L., Hibert, M., Frossard, N., & Bonnet, D. (14 August 2018). Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia. Journal of Medicinal Chemistry, 61, 7671-7686. doi:10.1021/acs.jmedchem.8b00657
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Abboud, D., Daly, A., Laschet, C., Pirotte, B., BECKERS, A., & Hanson, J. (05 July 2018). GPR101 orphan receptor: a novel cause of growth hormone deregulation [Paper presentation]. World Congress of Basic and Clinical Pharmacology WCP 2018- IUPHAR, Kyoto, Japan.

Abboud, D., Daly, A., Dupuis, N., Pirotte, B., BECKERS, A., & Hanson, J. (July 2018). The orphan receptor GPR101 as a novel cause of growth hormone deregulation [Poster presentation]. 18th International Union of Basic and Clinical Pharmacology (IUPHAR) congress.

Laschet, C., Dupuis, N., Geubelle, P., Abboud, D., & Hanson, J. (September 2017). Targeted mutagenesis of orphan GPCRs of the SREB family [Poster presentation]. International Symposium on GPCRs and G-proteins, Bonn, Germany.

Abboud, D., Daly, A., Laschet, C., Pirotte, B., BECKERS, A., & Hanson, J. (07 July 2017). Pharmacology of GPR101 [Paper presentation]. Transardennaise de l'hypophyse, Liège, Belgium.

Geubelle, P., Gilissen, J., Dilly, S., POMA, L., Dupuis, N., Laschet, C., Abboud, D., Inoue, A., Jouret, F., Pirotte, B., & Hanson, J. (May 2017). Identification and pharmacological characterization of succinate receptor agonists. British Journal of Pharmacology, 174 (9), 796-808. doi:10.1111/bph.13738
Peer reviewed vérifié par ORBi

Abboud, D., Daly, A., Dupuis, N., Laschet, C., Geubelle, P., Pirotte, B., BECKERS, A., & Hanson, J. (May 2017). GPR101 orphan GPCR: a novel cause of growth hormone deregulation [Poster presentation]. 19th European Congress of Endocrinology, Lisbon, Portugal.

Abboud, D., Daly, A., Dupuis, N., Laschet, C., Geubelle, P., Pirotte, B., BECKERS, A., & Hanson, J. (April 2017). GPR101 orphan GPCR: a novel cause of growth hormone deregulation [Poster presentation]. Belgian Society of Physiology and Pharmacology, Bruxelles, Belgium.

Abboud, D., & Hanson, J. (April 2017). Chemokine neutralization as an innovative therapeutic strategy for atopic dermatitis. Drug Discovery Today, 22 (4), 702-7011. doi:10.1016/j.drudis.2016.11.023
Peer reviewed vérifié par ORBi

Abboud, D., Dupuis, N., Laschet, C., Geubelle, P., Pirotte, B., & Hanson, J. (November 2016). GPR101 orphan GPCR: a novel cause of growth hormone deregulation [Poster presentation]. Fifth annual meeting of the CNRS GDR-3545, G Protein-coupled Receptors: from Physiology to Drugs (RCPG-Physio-Med), Tours, France.

Dupuis, N., Franssen, D., Laschet, C., Geubelle, P., Soni, A., Abboud, D., Twizere, J.-C., Pirotte, B., & Hanson, J. (26 September 2016). Small molecule ligands for the orphan GPR27 [Poster presentation]. GLISTEN meeting 2016 in Prague.

Laschet, C., Dupuis, N., Soni, A., Geubelle, P., Abboud, D., & Hanson, J. (September 2016). Targeted mutagenesis of orphan GPCRs of the SREB family [Poster presentation]. GLISTEN 2016 in Prague.

Abboud, D., Frossard, N., Galzi, J.-L., Bernard, P., Do, Q.-T., & Pillard, C. (31 March 2016). Composition contenant au moins un inhibiteur de certaines chimiokines, son procédé d’obtention et son utilisation en dermo-cosmétique pharmaceutique.

Abboud, D., Do, Q.-T., Frossard, N., Galzi, J.-L., Bernard, P., & Pillard, C. (31 March 2016). Utilisation dermocosmétique ou pharmaceutique d'une composition contenant au moins un inhibiteur de certaines chimiokines.

Abboud, D., Daubeuf, F., Do, Q. T., Utard, V., Villa, P., Haiech, J., Bonnet, D., Hibert, M., Bernard, P., Galzi, J.-L., & Frossard, N. (07 October 2015). A strategy to discover decoy chemokine ligands with an anti-inflammatory activity. Scientific Reports, 5, 14746. doi:10.1038/srep14746
Peer reviewed vérifié par ORBi

Abboud, D., Daubeuf, F., Do, Q. T., Utard, V., Bonnet, D., Hibert, M., Bernard, P., Frossard, N., & Galzi, J.-L. (August 2015). Combating skin inflammation with CXCL12 chemokine neutraligands [Paper presentation]. 12th World Congress on Inflammation, “Harnessing Patterns of Inflammation in Pursuit of Novel Therapeutics”.

Abboud, D., Daubeuf, F., Do, Q. T., Utard, V., Bonnet, D., Hibert, M., Bernard, P., Frossard, N., & Galzi, J.-L. (December 2014). A kinetic-based method to discover chemokine neutraligands [Paper presentation]. Troisième Journée Scientifique Publique de Medalis.

Abboud, D., Daubeuf, F., Do, Q. T., Utard, V., Bernard, P., Frossard, N., & Galzi, J.-L. (November 2014). Novel chemokine neutraligands targeting atopic dermatitis [Paper presentation]. SPIM Skin Physiology International Meeting.

Abboud, D., Daubeuf, F., Utard, V., Frossard, N., & Galzi, J.-L. (October 2014). Novel CCL17 chemokine neutraligands targeting atopic diseases [Poster presentation]. J2R journée des maladies respiratoires.

Abboud, D. (2014). Rôle des chimiokines dans les maladies atopiques: Etude pharmacologique à l’aide des neutraligands [Doctoral thesis, Université de Strasbourg]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/226567

Abboud, D., Daubeuf, F., Utard, V., Bernard, P., Frossard, N., & Galzi, J.-L. (June 2014). Novel CCL17 chemokine neutraligands targeting atopic diseases [Paper presentation]. Lungstorming.

Abboud, D., Daubeuf, F., Utard, V., Bernard, P., Frossard, N., & Galzi, J.-L. (October 2013). Novel chemokine neutraligands targeting atopic dermatitis [Poster presentation]. Second annual meeting of the CNRS GDR-3545, G Protein-coupled Receptors: from Physiology to Drugs (RCPG-Physio-Med).

Abboud, D., Daubeuf, F., Utard, V., Bernard, P., Frossard, N., & Galzi, J.-L. (July 2013). Novel chemokine neutraligands targeting atopic diseases [Poster presentation]. RICT/Société de Chimie Thérapeutique (SCT) - « Drug Discovery and Selection »
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Abboud, D., Daubeuf, F., Utard, V., Frossard, N., & Galzi, J.-L. (June 2013). Identification de neutraligands des chimiokines de CCL17 et CCL22 impliquées dans les maladies atopiques [Paper presentation]. Lungstorming.

Abboud, D., François, D., Utard, V., Frossard, N., & Galzi, J.-L. (October 2012). Novel CCL17 and CCL22 chemokine neutraligands targeting atopic dermatitis [Poster presentation]. First annual meeting of the CNRS GDR-3545, G Protein-coupled Receptors: from Physiology to Drugs (RCPG-Physio-Med).

Abboud, D., Daubeuf, F., Utard, V., Frossard, N., & Galzi, J.-L. (September 2012). How and why to find chemokine neutraligands? [Paper presentation]. EMBO Conference Series « Chemical Biology 2012 ».

Abboud, D., Daubeuf, F., Utard, V., Frossard, N., & Galzi, J.-L. (May 2012). Chemokines and atopic dermatitis [Poster presentation]. Gordon Research Conferences, « chemotactic cytokines, molecular and cellular mechanisms in health and disease ».

Abboud, D., Daubeuf, F., Utard, V., Frossard, N., Bonnet, D., Hibert, M., & Galzi, J.-L. (March 2012). Novel CCL17 chemokine neutraligands targeting atopic dermatitis [Paper presentation]. Première Journée scientifique publique de Medalis.

Abboud, D. (2010). Stability of parabens in breast cancer cells homogenates (MCF-7) [Master’s dissertation, Université Libanaise]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/226568

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