Profil

Van Steen Kristel

Dép. d'électric., électron. et informat. (Inst.Montefiore) > Bioinformatique

GIGA Medical Genomics - Biostat., biomed. & bioinformatics

See author's contact details
ORCID
0000-0001-9868-5033
Main Referenced Co-authors
Rutgeerts, P. (54)
Vermeire, S. (53)
Mahachie John, Jestinah  (50)
Van Assche, G. (33)
Vermeire, Severine (28)
Main Referenced Keywords
Humans (38); Male (24); Female (20); Adult (19); Middle Aged (16);
Main Referenced Unit & Research Centers
GIGA‐R - Giga‐Research - ULiège [BE] (3)
GIGA-Medical Genomics (1)
GIGA-R Medical Genomics (1)
Giga-Genetics - ULiège [BE] (1)
Human Genetics, BIO3 GIGA-R (1)
Main Referenced Disciplines
Gastroenterology & hepatology (105)
Genetics & genetic processes (73)
Life sciences: Multidisciplinary, general & others (70)
Physical, chemical, mathematical & earth Sciences: Multidisciplinary, general & others (20)
Oncology (16)

Publications (total 324)

The most downloaded
1358 downloads
Bessonov, K., Gadaleta, F., & Van Steen, K. (2017). Integration of Gene Expression and Methylation to unravel Biological Networks in Glioblastoma Patients. Genetic Epidemiology. doi:10.1002/gepi.22028 https://hdl.handle.net/2268/206156

The most cited

729 citations (Scopus®)

Vande Casteele, N., Ferrante, M., Van Assche, G., Ballet, V., Compernolle, G., Van Steen, K., Simoens, S., Rutgeerts, P., Gils, A., & Vermeire, S. (2015). Trough concentrations of infliximab guide dosing for patients with inflammatory bowel disease. Gastroenterology, 148 (7), 1320-9.e3. doi:10.1053/j.gastro.2015.02.031 https://hdl.handle.net/2268/198220

Melograna, F., Li, Z., Galazzo, G., van Best, N., Mommers, M., Penders, J., Stella, F., & Van Steen, K. (15 May 2023). Edge and modular significance assessment in individual-specific networks. Scientific Reports, 13 (1), 7868. doi:10.1038/s41598-023-34759-8
Peer Reviewed verified by ORBi

Li, Z., Melograna, F., Hoskens, H., Duroux, D., Marazita, M. L., Walsh, S., Weinberg, S. M., Shriver, M. D., Müller-Myhsok, B., Claes, P., & Van Steen, K. (2023). netMUG: a novel network-guided multi-view clustering workflow for dissecting genetic and facial heterogeneity. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/304725. doi:10.1101/2023.05.04.539350

Singhal, P., Veturi, Y., Dudek, S. M., Lucas, A., Frase, A., Van Steen, K., Schrodi, S. J., Fasel, D., Weng, C., Pendergrass, R., Schaid, D. J., Kullo, I. J., Dikilitas, O., Sleiman, P. M. A., Hakonarson, H., Moore, J. H., Williams, S. M., Ritchie, M. D., & Verma, S. S. (06 April 2023). Evidence of epistasis in regions of long-range linkage disequilibrium across five complex diseases in the UK Biobank and eMERGE datasets. American Journal of Human Genetics, 110 (4), 575 - 591. doi:10.1016/j.ajhg.2023.03.007
Peer Reviewed verified by ORBi

Poulet, C.* , Debit, A.* , Josse, C., Jerusalem, G., Azencott, C.-A., Bours, V., & Van Steen, K. (2023). Assessing Random Forest self-reproducibility for optimal short biomarker signature discovery. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/303314. doi:10.1101/2023.03.29.534695
* These authors have contributed equally to this work.

Duroux, D., & Van Steen, K. (19 March 2023). netANOVA: novel graph clustering technique with significance assessment via hierarchical ANOVA. Briefings in Bioinformatics, 24 (2). doi:10.1093/bib/bbad029
Peer Reviewed verified by ORBi

Yousefi, B., Melograna, F., Galazzo, G., van Best, N., Mommers, M., Penders, J., Schwikowski, B., & Van Steen, K. (22 January 2023). Capturing the dynamics of microbiomes using individual-specific networks. Frontiers in Microbiology, 14. doi:10.1101/2023.01.22.525058
Peer Reviewed verified by ORBi

Chaichoompu, K., Wilantho, A., Wangkumhang, P., Tongsima, S., Cavadas, B., Pereira, L., & Van Steen, K. (2023). Fine-scale subpopulation detection via an SNP-based unsupervised method: A case study on the 1000 Genomes Project resources. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 28 (2023), 245 - 256. doi:10.1142/9789811270611_0023
Peer Reviewed verified by ORBi

Riemens, R. J. M., Kenis, G., Nolz, J., Susano Chaves, S. C., Duroux, D., Pishva, E., Mastroeni, D., Van Steen, K., Haaf, T., & van den Hove, D. L. A. (08 December 2022). Targeted Methylation Profiling of Single Laser-Capture Microdissected Post-Mortem Brain Cells by Adapted Limiting Dilution Bisulfite Pyrosequencing (LDBSP). International Journal of Molecular Sciences, 23 (24), 15571. doi:10.3390/ijms232415571
Peer Reviewed verified by ORBi

Simons, C. C., Schouten, L. J., Godschalk, R. W., van Schooten, F.-J., Stoll, M., Van Steen, K., van den Brandt, P. A., & Weijenberg, M. P. (2022). Polymorphisms in the mTOR-PI3K-Akt pathway, energy balance-related exposures and colorectal cancer risk in the Netherlands Cohort Study. BioData Mining, 15 (1), 1-20. doi:10.1186/s13040-021-00286-3
Peer Reviewed verified by ORBi

Bhardwaj, A., Josse, C., VAN DAELE, D., Poulet, C., Chavez, M., Struman, I., & Van Steen, K. (2022). Deeper insights into long-term survival heterogeneity of Pancreatic Ductal Adenocarcinoma (PDAC) patients using integrative individual-and group-level transcriptome network analyses. Scientific Reports, 12 (11027). doi:10.1038/s41598-022-14592-1
Peer Reviewed verified by ORBi

Gregorich, M., Melograna, F., Sunqvist, M., Michiels, S., Van Steen, K., & Heinze, G. (2022). Individual-specific networks for prediction modelling–A scoping review of methods. BMC Medical Research Methodology, 22 (1), 1-17. doi:10.1186/s12874-022-01544-6
Peer Reviewed verified by ORBi

Joiret, M., Mahachie John, J., Gusareva, E., & Van Steen, K. (2022). Correction: Confounding of linkage disequilibrium patterns in large scale DNA based gene-gene interaction studies. BioData Mining, 15 (1), 1-1. doi:10.1186/s13040-022-00296-9
Peer Reviewed verified by ORBi

Duroux, D., Climente-González, H., Azencott, C.-A., & Van Steen, K. (2022). Interpretable network-guided epistasis detection. GigaScience, 11. doi:10.1093/gigascience/giab093
Peer Reviewed verified by ORBi

Walakira, A., Ocira, J., Duroux, D., Fouladi, R., Moškon, M., Rozman, D., & Van Steen, K. (2022). Detecting gene–gene interactions from GWAS using diffusion kernel principal components. BMC Bioinformatics, 23 (1), 1-18. doi:10.1186/s12859-022-04580-7
Peer Reviewed verified by ORBi

Kumari, P., Bikram Pradhan, Maria Koromina, George P. Patrinos, & Van Steen, K. (2022). Discovery of new drug indications for COVID- 19: A drug repurposing approach. PLoS ONE, 17 (5), 0267095. doi:10.1371/journal.pone.0267095
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Duroux, D., Van Steen, K., & Federico Melograna. (22 July 2021). Patient heterogeneity assessments via network-based ANOVA [Poster presentation]. 42nd Conference of the International Society for Clinical Biostatistics (ISCB).
Peer reviewed

Matschinske, J., Alcaraz, N., Benis, A., Golebiewski, M., Grimm, D. G., Heumos, L., Kacprowski, T., Lazareva, O., List, M., Louadi, Z., Josch K Pauling, Nico Pfeifer, Richard Röttger, Veit Schwämmle, Gregor Sturm, Alberto Traverso, Van Steen, K., Martiela Vaz de Freitas, Gerda Cristal Villalba Silva, ... David B Blumenthal. (2021). The AIMe registry for artificial intelligence in biomedical research. Nature Methods, 18 (10), 1128-1131. doi:10.1038/s41592-021-01241-0
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Riemens, R. J., Kenis, G., Nolz, J., Chaves, S. C. S., Duroux, D., Pishva, E., Mastroeni, D., Van Steen, K., Haaf, T., & van den Hove, D. L. (2021). Targeted methylation profiling of single laser-capture microdissected post-mortem brain cells by adapted limiting dilution bisulfite pyrosequencing (LDBSP). ORBi-University of Liège. https://orbi.uliege.be/handle/2268/292194.

Hall, M., Wallace, J., Lucas, A., Van Steen, K., Moore, J., & Ritchie, M. (2021). Novel EDGE encoding method enhances ability to identify genetic interactions. PLoS Genetics, 17 (6), 1009534. doi:10.1371/journal.pgen.1009534
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Zanin, M., Aitya, N. N. A. A., Basilio, J., Baumbach, J., Benis, A., Behera, C. C. K., Bucholc, M., Castiglione, F., Chouvarda, I., Comte, B., Dao, T.-T., Ding, X., Pujos-Guillot, E., Filipovic, N., Finn, D. D. P., Glass, D. D. H., Harel, N., Iesmantas, T., Ivanoska, I., ... Schmidt, H. H. H. W. H. (2021). An Early Stage Researcher's Primer on Systems Medicine Terminology. Network and Systems Medicine, 4 (1).
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Abegaz, F., Van Lishout, F., John, J. M. M., Chiachoompu, K., Bhardwaj, A., Duroux, D., Gusareva, E. S., Wei, Z., Hakonarson, H., & Van Steen, K. (2021). Performance of model-based multifactor dimensionality reduction methods for epistasis detection by controlling population structure. BioData Mining, 14 (1), 1-20. doi:10.1186/s13040-021-00247-w
Peer Reviewed verified by ORBi

Graff, S., Zanella, D., Stefanuto, P.-H., HENKET, M., PAULUS, V., GUISSARD, F., MOERMANS, C., Van Steen, K., Louis, R., & Schleich, F. (2021). Are Volatile Organic Compounds Able to Identify Airflow Decline in Asthma? Journal of Asthma and Allergy, 14, 67-70. doi:10.2147/JAA.S289278
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Comte, B., Baumbach, J., Benis, A., Basílio, J., Debeljak, N., Flobak, Å., Franken, C., Harel, N., He, F., Kuiper, M., Juan Albino Méndez Pérez, Estelle Pujos-Guillot, Tadeja Režen, Damjana Rozman, Johannes A Schmid, Jeanesse Scerri, Paolo Tieri, Van Steen, K., Sona Vasudevan, ... Harald HHW Schmidt. (2020). Network and systems medicine: position paper of the european collaboration on science and technology action on open multiscale systems medicine. Network and Systems Medicine, 3 (1), 67-90. doi:10.1089/nsm.2020.0004
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Chaichoompu, K., Abegaz, F., Cavadas, B., Fernandes, V., Muller-Myhsok, B., Pereira, L., & Van Steen, K. (2020). A different view on fine-scale population structure in Western African populations. Human Genetics, 139 (1), 45-59. doi:10.1007/s00439-019-02069-7
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Cottone, F., Collins, G. S., Anota, A., Sommer, K., Giesinger, J. M., Kieffer, J. M., Aaronson, N. K., Van Steen, K., Charton, E., & Castagnetti, F. (2020). Time to health-related quality of life improvement analysis was developed to enhance evaluation of modern anticancer therapies. Journal of Clinical Epidemiology. doi:10.1016/j.jclinepi.2020.06.016
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Detrez, I., Thomas, D., Van Steen, K., Ballet, V., Peeters, M., Hoylaerts, M. F., Van Assche, G., Vermeire, S., Ferrante, M., & Gils, A. (2020). Successful Infliximab Treatment is Associated With Reversal of Clotting Abnormalities in Inflammatory Bowel Disease Patients. Journal of Clinical Gastroenterology. doi:10.1097/MCG.0000000000001290
Peer Reviewed verified by ORBi

Bhardwaj, A., Van Steen, K., Maglogiannis, I., Iliadis, L., & Pimenidis, E. (2020). Multi-omics Data and Analytics Integration in Ovarian Cancer. In Artificial Intelligence Applications and Innovations. Springer International Publishing. doi:10.1007/978-3-030-49186-4_29
Peer reviewed

Stalidzans, E., Zanin, M., Tieri, P., Castiglione, F., Polster, A., Scheiner, S., Pahle, J., Stres, B., List, M., Baumbach, J., Lautizi, M., Van Steen, K., & Schmidt, H. (2020). Mechanistic Modeling and Multiscale Applications for Precision Medicine: Theory and Practice. Network and Systems Medicine. doi:10.1089/nsm.2020.0002
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Li, J., Gonzalez, T., White, J. D., Indencleef, K., Hoskens, H., Castrillon, A. O., Nauwelaers, N., Zaidi, A., Eller, R. J., Günther, T., Svensson, E. M., Jakobsson, M., Walsh, S., Van Steen, K., Shriver, M. D., & Claes, P. (2020). Robust Genome-Wide Ancestry Inference for Heterogeneous Datasets and Ancestry Facial Imaging based on the 1000 Genomes Project. Scientific Reports. doi:10.1038/s41598-020-68259-w
Peer Reviewed verified by ORBi

Duroux, D., Climente-González, H., Wienbrandt, L., Van Steen, K., Maglogiannis, I., Iliadis, L., & Pimenidis, E. (2020). Network Aggregation to Enhance Results Derived from Multiple Analytics. In Artificial Intelligence Applications and Innovations. Springer International Publishing. doi:10.1007/978-3-030-49161-1_12
Peer reviewed

Duroux, D.* , Héctor Climente-González* , Camargo Fernandez Baca, A., Lars Wienbrandt, David Ellinghaus, Chloe-Agathe Azencott, & Van Steen, K. (14 October 2019). Improving efficiency in epistasis detection with a gene-based analysis using functional filters [Poster presentation]. IGES.
Peer reviewed
* These authors have contributed equally to this work.

Joiret, M., Mahachie John, J., Gusareva, E., & Van Steen, K. (10 June 2019). Confounding of linkage disequilibrium patterns in large scale DNA based gene-gene interaction studies. BioData Mining, 12 (11), 1-23. doi:10.1186/s13040-019-0199-7
Peer Reviewed verified by ORBi

Debit, A., Poulet, C., JOSSE, C., Azencott, C.-A., Jerusalem, G., Van Steen, K., & BOURS, V. (15 March 2019). TOWARDS AN ACCURATE CANCER DIAGNOSIS MODELIZATION:COMPARISON OF RANDOM FOREST STRATEGIES [Poster presentation]. 19th BeSHG meeting 15th March 2019 Liege, Belgium, Liege, Belgium.

Cottone, F., Deliu, N., Collins, G., Anota, A., Bonnetain, F., Van Steen, K., Cella, D., & Efficace, F. (2019). Modelling strategies to improve parameter estimates in prognostic factors analyses with patient-reported outcomes in oncology. Quality of Life Research. doi:10.1007/s11136-018-02097-2
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Van Steen, K., & Moore, J. (2019). How to increase our belief in discovered statistical interactions via large-scale association studies? Human Genetics. doi:10.1007/s00439-019-01987-w
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SCHLEICH, F., Zanella, D., Stefanuto, P.-H., Dallinga, J., HENKET, M., Wouters, E. F. M., Van Steen, K., Van Schooten, F., Focant, J.-F., & Louis, R. (2019). Exhaled Volatile Organic Compounds Are Able to Discriminate Between Neutrophilic and Eosinophilic Asthma. American Journal of Respiratory and Critical Care Medicine, 200 (4), 444-453. doi:10.1164/rccm.201811-2210OC
Peer Reviewed verified by ORBi

Chaichoompu, K., Abegaz Yazew, F., Tongsima, S., Shaw, P. J., Sakuntabhai, A., Pereira, L., & Van Steen, K. (2019). IPCAPS: an R package for iterative pruning to capture population structure. Source Code for Biology and Medicine, 14. doi:10.1186/s13029-019-0072-6
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Romagnoni, A., Jegou, S., Van Steen, K., Wainrib, G., & Hugot, J.-P. (2019). Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data. Scientific Reports, 9 (1), 10351. doi:10.1038/s41598-019-46649-z
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Abegaz, F., Chaichoompu, K., Genin, E., Fardo, D. W., König, I. R., Mahachie John, J. M., & Van Steen, K. (2019). Principals about principal components in statistical genetics. Briefings in Bioinformatics. doi:10.1093/bib/bby081
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Zhang, J., Wei, Z., Cardinale, C. J., Gusareva, E., Van Steen, K., Sleiman, P., Hakonarson, H., & Consortium, I. I. B. D. G. (2019). Multiple Epistasis Interactions Within MHC Are Associated With Ulcerative Colitis. FRONTIERS IN GENETICS, 10. doi:10.3389/fgene.2019.00257
Peer reviewed

Abegaz, F., Van Lishout, F., Mahachie John, J. M., Chiachoompu, K., Bhardwaj, A., Gusareva, E. S., Wei, Z., Hakonarson, H., Van Steen, K., & International, I. B. D. G. C. (2019). Epistasis Detection in Genome-Wide Screening for Complex Human Diseases in Structured Populations. Systems Medicine, 2 (1), 19-27.
Peer reviewed

Debit, A., Poulet, C., JOSSE, C., Van Steen, K., JERUSALEM, G., Bours, V., & Azencott, C.-A. (05 October 2018). Towards an accurate cancer diagnosis modelization: Comparison of Random Forest strategies [Poster presentation]. 5th conference Bioinformatics for young international researchers expo byteMAL 2018, Liege, Belgium.

Wang, M. H. T., Cordell, H. J., & Van Steen, K. (2018). Statistical methods for genome-wide association studies. Seminars in Cancer Biology. doi:10.1016/j.semcancer.2018.04.008
Peer Reviewed verified by ORBi

Dreesen, E., Van Stappen, T., Ballet, V., Peeters, M., Compernolle, G., Tops, S., Van Steen, K., Van Assche, G., Ferrante, M., Vermeire, S., & Gils, A. (2018). Anti-infliximab antibody concentrations can guide treatment intensification in patients with Crohn's disease who lose clinical response. Alimentary Pharmacology and Therapeutics, 47 (3), 346-355. doi:10.1111/apt.14452
Peer Reviewed verified by ORBi

Ritchie, M., & Van Steen, K. (2018). The search for gene-gene interactions in genome-wide association studies: challenges in abundance of methods, practical considerations, and biological interpretation. Annals of Translational Medicine, 6 (8), 157. doi:10.21037/atm.2018.04.05
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Gusareva, E. S., Twizere, J.-C., Sleegers, K., Dourlen, P., Abisambra, J. F., Meier, S., Cloyd, R., Weiss, B., Dermaut, B., Bessonov, K., van der Lee, S. J., Carrasquillo, M. M., Katsumata, Y., Cherkaoui, M., Asselbergh, B., Ikram, M. A., Mayeux, R., Farrer, L. A., Haines, J. L., ... Van Steen, K. (2018). Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease. Neurobiology of Aging, 72, 188.e3-188.e12. doi:10.1016/j.neurobiolaging.2018.08.001
Peer Reviewed verified by ORBi

Noël, G., Chaichoompu, K., Leclercq, G., Fabre, E., Gengler, N., Van Steen, K., & Francis, F. (15 November 2017). Human based genetic tools to refine genetic populations structure of honey bees (Apis mellifera ssp L.) (Hymenoptera: Apoidea: Apidae) colonies at regional scale [Paper presentation]. EUROPEAN PhD NETWORK "INSECT SCIENCE" VIII Annual Meeting.

Chaichoompu, K., Fentaw Abegaz, Y., Tongsima, S., Shaw, P. J., Sakuntabhai, A., Cavadas, B., Pereira, L., & Van Steen, K. (09 September 2017). Using IPCAPS to identify fine-scale population structure [Poster presentation]. The International Genetic Epidemiology Society 2017, Cambridge, United Kingdom.

Chaichoompu, K., Yazew, F. A., Tongsima, S., Shaw, P. J., Sakuntabhai, A., Pereira, L., & Van Steen, K. (10 July 2017). Determining fine population structure using iterative pruning [Poster presentation]. Drug Discovery & Therapy World Congress 2017, Boston, United States.

Debit, A., Wenric, S., JOSSE, C., Van Steen, K., & Bours, V. (May 2017). Normalization and correction for batch effects via RUV for RNA-seq data: practical implications for Breast Cancer Research [Poster presentation]. European Human Genetics Conference ESHG 2017, Copenhagen, Denmark.

Chaichoompu, K., Yazew, F. A., Tongsima, S., Shaw, P. J., Sakuntabhai, A., Pereira, L., & Van Steen, K. (25 April 2017). Determining fine population structure using iterative pruning [Poster presentation]. BIT’s 2nd Annual International Congress of Genetics (ICG-2017), Xi'an, China.

Chaichoompu, K., Yazew, F. A., Tongsima, S., Shaw, P. J., Sakuntabhai, A., & Van Steen, K. (01 February 2017). Using unsupervised clustering method and SNP-based information to identify fine-level population structure [Poster presentation]. GIGA DAY 2017, Liege, Belgium.

Machiels, K., Sabino, J., Vandermosten, L., Joossens, M., Arijs, I., de Bruyn, M., Eeckhaut, V., Van Assche, G., Ferrante, M., Verhaegen, J., Van Steen, K., Van Immerseel, F., Huys, G., Verbeke, K., Wolthuis, A., de Buck Van Overstraeten, A., D'Hoore, A., Rutgeerts, P., & Vermeire, S. (2017). Specific members of the predominant gut microbiota predict pouchitis following colectomy and IPAA in UC. Gut, 66 (1), 79-88. doi:10.1136/gutjnl-2015-309398
Peer Reviewed verified by ORBi

Elands, R. J. J., Simons, C. C. J. M., Riemenschneider, M., Isaacs, A., Schouten, L. J., Verhage, B. A., Van Steen, K., Godschalk, R. W. L., Van Den Brandt, P. A., Stoll, M., & Weijenberg, M. P. (2017). A systematic SNP selection approach to identify mechanisms underlying disease aetiology: Linking height to post-menopausal breast and colorectal cancer risk. Scientific Reports, 7. doi:10.1038/srep41034
Peer Reviewed verified by ORBi

Bessonov, K., Gadaleta, F., & Van Steen, K. (2017). Integration of Gene Expression and Methylation to unravel Biological Networks in Glioblastoma Patients. Genetic Epidemiology. doi:10.1002/gepi.22028
Peer Reviewed verified by ORBi

Pineda, S., Van Steen, K., & Malats, N. (2017). Integrative eQTL analysis of tumor and host omics data in individuals with bladder cancer. Genetic Epidemiology, 41 (6), 567-573. doi:10.1002/gepi.22053
Peer Reviewed verified by ORBi

Bisschops, R., Bessissow, T., Dekker, E., East, J. E., Para-Blanco, A., Ragunath, K., Bhandari, P., Rutter, M., Schoon, E., Wilson, A., John, J. M., Van Steen, K., Baert, F., & Ferrante, M. (2017). Pit pattern analysis with high-definition chromoendoscopy and narrow-band imaging for optical diagnosis of dysplasia in patients with ulcerative colitis. Gastrointestinal Endoscopy, 86 (6), 1100-1106.e1. doi:10.1016/j.gie.2017.09.024
Peer Reviewed verified by ORBi

Detrez, I., Van Steen, K., Segaert, S., & Gils, A. (2017). The association between etanercept serum concentration and psoriasis severity is highly age-dependent. Clinical Science, 131 (11), 1179-1189. doi:10.1042/CS20170048
Peer Reviewed verified by ORBi

Bessonov, K., & Van Steen, K. (2016). Practical aspects of gene regulatory inference via conditional inference forests from expression data. Genetic Epidemiology. doi:10.1002/gepi.22017
Peer Reviewed verified by ORBi

Chaichoompu, K., Tongsima, S., Shaw, P. J., Sakuntabhai, A., & Van Steen, K. (17 June 2016). Capturing fine-level structure using unsupervised clustering method with multiple data types [Poster presentation]. byteMAL (Bioinformatics for Young inTernational researchers) conference in Aachen, Aachen, Germany.

Chaichoompu, K., Tongsima, S., Shaw, P. J., Sakuntabhai, A., & Van Steen, K. (21 May 2016). A novel unsupervised clustering approach with multiple data types to reveal fine-level structure [Poster presentation]. the European Human Genetics Conference 2016 (ESHG 2016), Barcelona, Barcelona, Spain.

Chaichoompu, K., Tongsima, S., Shaw, P. J., Sakuntabhai, A., & Van Steen, K. (03 April 2016). Iterative pruning method of unsupervised clustering for categorical data [Poster presentation]. the 13th International Congress of Human Genetics (ICHG 2016), Kyoto, Japan.

Lopez de Maturana, E., Pineda, S., Brand, A., Van Steen, K., & Malats, N. (2016). Toward the integration of omics data in epidemiological studies: still a "long and winding road". Genetic Epidemiology, 40, 558-569. doi:10.1002/gepi.21992
Peer Reviewed verified by ORBi

Gola, D., Mahachie John, J., Van Steen, K., & Konig, I. R. (2016). A roadmap to multifactor dimensionality reduction methods. Briefings in Bioinformatics, 17 (2), 293-308. doi:10.1093/bib/bbv038
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Pineda San Juan, S., Real, F. X., Kogevinas, M., Carrato, A., Chanock, S. J., Malats, N., & Van Steen, K. (2015). Integration Analysis of Three Omics Data Using Penalized Regression Methods: An Application to Bladder Cancer. PLoS Genetics. doi:10.1371/journal.pgen.1005689
Peer Reviewed verified by ORBi

Van Lishout, F., Gadaleta, F., Moore, J. H., Wehenkel, L., & Van Steen, K. (20 November 2015). gammaMAXT: a fast multiple-testing correction algorithm. BioData Mining, 8 (36). doi:10.1186/s13040-015-0069-x
Peer Reviewed verified by ORBi

Gusareva, E., Wei, Z., Traherne, J. A., Hugot, J.-P., Cleynen, I., Cho, J. H., Hakonarson, H., & Van Steen, K. (05 October 2015). Epistasis associated to inflammatory bowel disease (IBD) in humans [Poster presentation]. International Genetic Epidemiology Society (IGES) meeting, Baltimore, United States.

Chaichoompu, K., Cleynen, I., Fouladi, R., Ellinghaus, D., Hübenthal, M., Van Steen, K., & on behalf of the International inflammatory bowel disease genetics consortium (IIBDGC). (03 October 2015). Detecting patient subgroups using reduced set of disease-related markers with iterative pruning Principal Component Analysis (ipPCA) [Poster presentation]. the 24th annual conference of the International Genetic Epidemiology Society (IGES 2015), Baltimore, Maryland, United States.

Gusareva, E., van der Lee, S., Katsumata, Y., Carrasquillo, M. M., Bellenguez, C., Hofman, A. A., Ikram, A. M. A., Harold, D., Williams, J., Amouyel, P., van Duijn, C., Fardo, D., Ertekin-Taner, N., Lambert, J.-C., & Van Steen, K. (2015). Biological validation of statistical epistasis signals [Paper presentation]. COST Action (BM1204): An integrated European platform for pancreas cancer research: from basic science to clinical and public health interventions for a rare disease, Barcelona, Spain.

Fouladi, R., Bessonov, K., Van Lishout, F., & Van Steen, K. (July 2015). Model-Based Multifactor Dimensionality Reduction for Rare Variant Association Analysis. Human Heredity, 79, 157-167. doi:10.1159/000381286
Peer Reviewed verified by ORBi

Bessonov, K., Gusareva, E., & Van Steen, K. (2015). A cautionary note on the impact of protocol changes for Genome-Wide Association SNP x SNP Interaction studies: an example on ankylosing spondylitis. Human Genetics. doi:10.1007/s00439-015-1560-7
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Goyette, P., Boucher, G., Mallon, D., Ellinghaus, E., Jostins, L., Huang, H., Ripke, S., Gusareva, E., Annese, V., Hauser, S. L., Oksenberg, J. R., Thomsen, I., Leslie, S., Theatre, E., Georges, M., Louis, E., Daly, M. J., Van Steen, K., Duerr, R. H., ... Rioux, J. D. (05 January 2015). High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis. Nature Genetics, 47 (2), 172-9. doi:10.1038/ng.3176
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Cleynen, I., Konings, P., Robberecht, C., Laukens, D., Amininejad, L., Théâtre, E., Machiels, K., Arijs, I., Rutgeerts, P., Louis, E., Franchimont, D., De Vos, M., Van Steen, K., Georges, M., Moreau, Y., Vermeesch, J., & Vermeire, S. (2015). Genome-Wide Copy Number Variation Scan Identifies Complement Component C4 as Novel Susceptibility Gene for Crohn's Disease. Inflammatory Bowel Diseases. doi:10.1097/MIB.0000000000000623
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Van Steen, K., & Malats, N. (2015). Perspectives on Data Integration in Human Complex Disease Analysis. In Big Data Analytics in Bioinformatics and Healthcare (pp. 39). IGI-global. doi:10.4018/978-1-4666-6611-5.ch013
Peer reviewed

Li, Z., Vermeire, S., Bullens, D., Ferrante, M., Van Steen, K., Noman, M., Rutgeerts, P., Ceuppens, J. L., & Van Assche, G. (2015). Restoration of Foxp3+ Regulatory T-cell Subsets and Foxp3- Type 1 Regulatory-like T Cells in Inflammatory Bowel Diseases During Anti-tumor Necrosis Factor Therapy. Inflammatory Bowel Diseases, 21 (10), 2418-28. doi:10.1097/MIB.0000000000000509
Peer Reviewed verified by ORBi

Drobne, D., Bossuyt, P., Breynaert, C., Cattaert, T., Vande Casteele, N., Compernolle, G., Jurgens, M., Ferrante, M., Ballet, V., Wollants, W.-J., Cleynen, I., Van Steen, K., Gils, A., Rutgeerts, P., Vermeire, S., & Van Assche, G. (2015). Withdrawal of Immunomodulators After Co-treatment Does Not Reduce Trough Level of Infliximab in Patients With Crohn's Disease. Clinical Gastroenterology and Hepatology, 13 (3), 514-521.e4. doi:10.1016/j.cgh.2014.07.027
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Bollen, L., Vande Casteele, N., Peeters, M., Bessonov, K., Van Steen, K., Rutgeerts, P., Ferrante, M., Hoylaerts, M. F., Vermeire, S., & Gils, A. (2015). Short-term Effect of Infliximab Is Reflected in the Clot Lysis Profile of Patients with Inflammatory Bowel Disease: A Prospective Study. Inflammatory Bowel Diseases, 21 (3), 570-8. doi:10.1097/MIB.0000000000000301
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Park, T., Van Steen, K., Lou, X.-Y., & Xiong, M. (2015). Statistical Analysis of High-Dimensional Genetic Data in Complex Traits. BioMed Research International, 2015, 564273. doi:10.1155/2015/564273
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Pineda San Juan, S., Gómez-Rubio, P., Antoni, P., Bessonov, K., Márquez, M., Kogevinas, M., Real, F., Van Steen, K., & Malats, N. (2015). Framework for the integration of genomics, epigenomics, and transcriptomics in complex diseases. Human Heredity.
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Vande Casteele, N., Ferrante, M., Van Assche, G., Ballet, V., Compernolle, G., Van Steen, K., Simoens, S., Rutgeerts, P., Gils, A., & Vermeire, S. (2015). Trough concentrations of infliximab guide dosing for patients with inflammatory bowel disease. Gastroenterology, 148 (7), 1320-9.e3. doi:10.1053/j.gastro.2015.02.031
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Li, Z., Vermeire, S., Bullens, D., Ferrante, M., Van Steen, K., Noman, M., Bossuyt, X., Rutgeerts, P., Ceuppens, J. L., & Van Assche, G. (2015). Anti-Tumor Necrosis Factor Therapy Restores Peripheral Blood B-cell Subsets and CD40 Expression in Inflammatory Bowel Diseases. Inflammatory Bowel Diseases, 21 (12), 2787-96. doi:10.1097/MIB.0000000000000554
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Pineda, S., Gomez-Rubio, P., Picornell, A., Bessonov, K., Marquez, M., Kogevinas, M., Real, F. X., Van Steen, K., & Malats, N. (2015). Framework for the Integration of Genomics, Epigenomics and Transcriptomics in Complex Diseases. Human Heredity, 79 (3-4), 124-36. doi:10.1159/000381184
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Grange, L., Bureau, J.-F., Nikolayeva, I., Paul, R., Van Steen, K., Schwikowski, B., & Sakuntabhai, A. (2015). Filter-free exhaustive odds ratio-based genome-wide interaction approach pinpoints evidence for interaction in the HLA region in psoriasis. BMC Genetics, 16 (1), 11. doi:10.1186/s12863-015-0174-3
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Chaichoompu, K., Fouladi, R., Wangkumhang, P., Wilantho, A., Chareanchim, W., Shaw, P. J., Tongsima, S., Sakuntabhai, A., & Van Steen, K. (26 November 2014). Combining Genotype with LD-based haplotype information as input for iterative pruning principal component analysis (ipPCA) to improve population clustering [Paper presentation]. Capita Selecta in Complex Disease Analysis conference and EU COST Pancreas annual meeting (CSCDA 2014), Liege, Belgium.

Pineda San Juan, S., Malats, N., & Van Steen, K. (24 November 2014). Integration analysis of ‘OMICS’ data using penalized regression methods: An application to bladder cancer [Paper presentation]. CSCDA meeting 2014.

Van Lishout, F., Gadaleta, F., Moore, J. H., Wehenkel, L., & Van Steen, K. (2014). gammaMAXT: a fast multiple-testing correction algorithm. In ERCIM 2014 Abstract Book (pp. 47).
Peer reviewed

Gusareva, E., & Van Steen, K. (November 2014). Practical aspects of genome-wide association interaction analysis. Human Genetics, 133 (11), 1343-58. doi:10.1007/s00439-014-1480-y
Peer Reviewed verified by ORBi

Pineda San Juan, S., Malats, N., & Van Steen, K. (03 September 2014). Integration analysis of ‘OMICS’ data using penalized regression methods: An application to bladder cancer [Paper presentation]. SEE: XXXII Scientific Meeting of the Spanish Epidemiology Society.

Chaichoompu, K., Fouladi, R., Wangkumhang, P., Wilantho, A., Chareanchim, W., Tongsima, S., Sakuntabhai, A., & Van Steen, K. (28 August 2014). Combining genotype with allelic association as input for iterative pruning principal component analysis (ipPCA) to resolve population substructures [Poster presentation]. The 23rd annual conference of the International Genetic Epidemiology Society (IGES 2014), Vienna, Austria.

Gusareva, E., Carrasquillo, M. M., Bellenguez, C., Cuyvers, E., Colon, S., Graff-Radford, N. R., Petersen, R. C., Dickson, D. W., Mahachie John, J., Bessonov, K., Van Broeckhoven, C., Harold, D., Williams, J., Amouyel, P., Sleegers, K., Ertekin-Taner, N., Lambert, J.-C., & Van Steen, K. (2014). Genome-Wide Association Interaction Analysis for Alzheimer’s Disease. Neurobiology of Aging. doi:10.1016/j.neurobiolaging.2014.05.014
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Chaichoompu, K., Fouladi, R., Wangkumhang, P., Wilantho, A., Chareanchim, W., Tongsima, S., Sakuntabhai, A., & Van Steen, K. (29 April 2014). LD-based haplotype encoding scheme with iterative pruning principal component analysis (ipPCA) to retrieve population substructures [Poster presentation]. The Human Genome Meeting (HGM 2014), Geneva, Switzerland.

Pineda San Juan, S., Malats, N., & Van Steen, K. (01 April 2014). Integration analysis of ‘OMICS’ data using penalized regression methods: An application to bladder cancer [Paper presentation]. EMGM: European Mathematical Genetics Meeting Köln, Germany.

Gusareva, E., Bellenguez, C., Cuyvers, E., Colon, S., Carrasquillo, M., Graff-Radford, N., Petersen, R., Dickson, D., Younkin, S., Mahachie John, J., Bessonov, K., Van Broeckhoven, C., Harold, D., Williams, J., Amouyel, P., Sleegers, K., Ertekin-Taner, N., Lambert, J.-C., & Van Steen, K. (27 January 2014). Genome-wide association interaction analysis for Alzheimer’s disease [Poster presentation]. GIGA-DAY 2014, Liege, Belgium.

Gadaleta, F., & Van Steen, K. (2014). Discovering main genetic interactions with LABNet LAsso-based network inference. PLoS ONE, 9 (11), 110451. doi:10.1371/journal.pone.0110451
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Beigel, F., Steinborn, A., Schnitzler, F., Tillack, C., Breiteneicher, S., John, J. M., Van Steen, K., Laubender, R. P., Goke, B., Seiderer, J., Brand, S., & Ochsenkuhn, T. (2014). Risk of malignancies in patients with inflammatory bowel disease treated with thiopurines or anti-TNF alpha antibodies. Pharmacoepidemiology and Drug Safety, 23 (7), 735-44. doi:10.1002/pds.3621
Peer Reviewed verified by ORBi

Boulesteix, A.-L., Janitza, S., Hapfelmeier, A., Van Steen, K., & Strobl, C. (2014). Letter to the Editor: On the term 'interaction' and related phrases in the literature on Random Forests. Briefings in Bioinformatics. doi:10.1093/bib/bbu012
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Bollen, L., Peetermans, M., Peeters, M., Van Steen, K., Hoylaerts, M. F., Declerck, P. J., Verhamme, P., & Gils, A. (2014). Active PAI-1 as marker for venous thromboembolism: case-control study using a comprehensive panel of PAI-1 and TAFI assays. Thrombosis Research, 134 (5), 1097-102. doi:10.1016/j.thromres.2014.08.007
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Savenije, O. E., Mahachie John, J., Granell, R., Kerkhof, M., Dijk, F. N., de Jongste, J. C., Smit, H. A., Brunekreef, B., Postma, D. S., Van Steen, K., Henderson, J., & Koppelman, G. H. (2014). Association of IL33-IL-1 receptor-like 1 (IL1RL1) pathway polymorphisms with wheezing phenotypes and asthma in childhood. Journal of Allergy and Clinical Immunology. doi:10.1016/j.jaci.2013.12.1080
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de Bruyn, M., Arijs, I., Wollants, W.-J., Machiels, K., Van Steen, K., Van Assche, G., Ferrante, M., Rutgeerts, P., Vermeire, S., & Opdenakker, G. (2014). Neutrophil gelatinase B-associated lipocalin and matrix metalloproteinase-9 complex as a surrogate serum marker of mucosal healing in ulcerative colitis. Inflammatory Bowel Diseases, 20 (7), 1198-207. doi:10.1097/MIB.0000000000000068
Peer Reviewed verified by ORBi

De Greef, E., Maus, B., Smets, F., Van Biervliet, S., John, J. M. M., Van Steen, K., & Veereman, G. (2014). Diagnosing and treating pediatric Crohn's disease patients: is there a difference between adult and pediatric gastroenterologist's practices ? Results of the BELCRO cohort. Acta Gastro-Enterologica Belgica, 77 (1), 25-9.
Peer Reviewed verified by ORBi

Galesloot, T. E., Van Steen, K., Kiemeney, L. A. L. M., Janss, L. L., & Vermeulen, S. H. (2014). A comparison of multivariate genome-wide association methods. PLoS ONE, 9 (4), 95923. doi:10.1371/journal.pone.0095923
Peer Reviewed verified by ORBi

Van Lishout, F., Bessonov, K., Duan, Q., Gusareva, E., Mahachie John, J., Tantishira, K., & Van Steen, K. (25 October 2013). Genome-wide environmental interaction analysis using multidimensional data reduction principles to identify asthma pharmacogenetic loci in relation to corticosteroid therapy [Poster presentation]. Annual Society of Human Genetics Annual Meeting 2013, Boston, United States.

Gusareva, E., Bellenguez, C., Cuyvers, E., Colon, S., Carrasquillo, M., Graff-Radford, N., Petersen, R., Dickson, D., Younkin, S., Mahachie John, J., Bessonov, K., Van Broeckhoven, C., Harold, D., Williams, J., Amouyel, P., Sleegers, K., Ertekin-Taner, N., Lambert, J.-C., & Van Steen, K. (2013). Genome-wide association interaction analysis for Alzheimer’s disease [Paper presentation]. The 14th International Meeting on Human Genome Variation and Complex Genome Analysis (HGV2013), Seoul, South Korea.

Bessonov, K., & Van Steen, K. (17 September 2013). Replication of large-scale epistasis studies: an example on ankylosing spondylitis [Poster presentation]. International Genetic Epidemiology Society (IGES) 2013, Chicago, United States.

Pineda San Juan, S., Milne, R., Van Steen, K., & Malats, N. (22 May 2013). Statistical approaches for the integration of 'omics' and epidemiological data: an application to bladder cancer [Paper presentation]. XIV Scientific Meeting of the Spanish Biometrics Society.

Veereman, G., Mahachie John, J., De Greef, E., Smets, F., Van Biervliet, S., & Van Steen, K. (2013). Therapeutic Strategy and Patient Outcome during the First 2 Years of Pediatric Crohn’s Disease. Journal of Pediatric Gastroenterology and Nutrition.
Peer Reviewed verified by ORBi

Pineda San Juan, S., Milne, R., Van Steen, K., & Malats, N. (May 2013). Statistical approaches for the integration of 'omics' and epidemiological data: an application to bladder cancer [Paper presentation]. XIV Scientific Meeting of the Spanish Biometrics Society.

Gusareva, E., Cuyvers, E., Colon, S., Carrasquillo, M., Van Broeckhoven, C., Bellenguez, C., Amouyel, F., Sleegers, K., Ertekin-Taner, N., Lambert, J.-C., & Van Steen, K. (2013). Genome-wide association interaction analysis for complex diseases: an example on Alzheimer’s disease [Paper presentation]. The 7th meeting of the Eastern Mediterranean Region of the International Biometric Society (EMR-IBS), Tel-Aviv, Israel.

Van Lishout, F., Mahachie John, J., Gusareva, E., Urrea, V., Cleynen, I., Theatre, E., CHARLOTEAUX, B., Calle, M. L., Wehenkel, L., & Van Steen, K. (24 April 2013). An efficient algorithm to perform multiple testing in epistasis screening. BMC Bioinformatics, 14, 138. doi:10.1186/1471-2105-14-138
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Gusareva, E., Bellenguez, C., Sleegers, K., Ertekin-Taner, N., Harold, D., Lambert, J.-C., & Van Steen, K. (March 2013). Genome-wide Epistasis Screening for Alzheimer‘s Disease [Poster presentation]. The ACMG Annual Clinical Genetics Meeting, Phoenix, United States - Arizona.

Veereman, G., Mahachie John, J., De Greef, E., Smets, F., Van Biervliet, S., & Van Steen, K. (2013). Therapeutic Strategy and Patient Outcome during the First 2 Years of Pediatric Crohn’s Disease. Acta Gastro-Enterologica Belgica.
Peer Reviewed verified by ORBi

Salvatore, S., Salvatoni, A., Van Berkel, M., Van Steen, K., Unmarino, D., Ghanma, A., Hauser, B., & Vandenplas, Y. (2013). Esophageal impedance baseline is age dependent. Journal of Pediatric Gastroenterology and Nutrition, 57 (4), 506-13. doi:10.1097/MPG.0b013e31829b68cd
Peer Reviewed verified by ORBi

Wei, Z., Wang, W., Bradfield, J., Li, J., Cardinale, C., Frackelton, E., Kim, C., Mentch, F., Van Steen, K., Visscher, P. M., Baldassano, R. N., & Hakonarson, H. (2013). Large Sample Size, Wide Variant Spectrum, and Advanced Machine-Learning Technique Boost Risk Prediction for Inflammatory Bowel Disease. American Journal of Human Genetics. doi:10.1016/j.ajhg.2013.05.002
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Hoefkens, E., Nys, K., John, J. M., Van Steen, K., Arijs, I., Van der Goten, J., Van Assche, G., Agostinis, P., Rutgeerts, P., Vermeire, S., & Cleynen, I. (2013). Genetic association and functional role of Crohn disease risk alleles involved in microbial sensing, autophagy, and endoplasmic reticulum (ER) stress. Autophagy, 9 (12), 2046-55. doi:10.4161/auto.26337
Peer Reviewed verified by ORBi

Maus, B., Jung, C., Mahachie John, J., Hugot, J.-P., Genin, E., & Van Steen, K. (2013). Molecular reclassification of Crohn's disease: a cautionary note on population stratification. PLoS ONE, 8 (10), 77720. doi:10.1371/journal.pone.0077720
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Cleynen, I., Vazeille, E., Artieda, M., Verspaget, H. W., Szczypiorska, M., Bringer, M.-A., Lakatos, P. L., Seibold, F., Parnell, K., Weersma, R. K., Mahachie John, J., Morgan-Walsh, R., Staelens, D., Arijs, I., De Hertogh, G., Muller, S., Tordai, A., Hommes, D. W., Ahmad, T., ... Darfeuille-Michaud, A. (2013). Genetic and microbial factors modulating the ubiquitin proteasome system in inflammatory bowel disease. Gut. doi:10.1136/gutjnl-2012-303205
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Breynaert, C., Dresselaers, T., Perrier, C., Arijs, I., Cremer, J., Van Lommel, L., Van Steen, K., Ferrante, M., Schuit, F., Vermeire, S., Rutgeerts, P., Himmelreich, U., Ceuppens, J. L., Geboes, K., & Van Assche, G. (2013). Unique gene expression and MR T2 relaxometry patterns define chronic murine dextran sodium sulphate colitis as a model for connective tissue changes in human Crohn's disease. PLoS ONE, 8 (7), 68876. doi:10.1371/journal.pone.0068876
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Mahachie John, J., Gusareva, E., Van Lishout, F., & Van Steen, K. (2013). A robustness study to investigate the performance of parametric and non-parametric tests used in Model-Based Multifactor Dimensionality Reduction Epistasis Detection. BioData Mining.
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Hoefkens, E., Mahachie John, J., Van Steen, K., Nys, K., Van Assche, G., Agostinis, P., Rutgeerts, P., Vermeire, S., & Cleynen, I. (2013). Crohn’s disease susceptibility genes involved in microbial sensing, autophagy and endoplasmic reticulum (er) stress and their interaction. Autophagy.
Peer Reviewed verified by ORBi

De Greef, E., Mahachie John, J., Hoffman, I., Smets, F., Van Biervliet, S., Scaillon, M., Hauser, B., Paquot, I., Alliet, P., Arts, W., Dewit, O., Peeters, H., Baert, F., D'Haens, G., Rahier, J.-F., Etienne, I., Bauraind, O., Van Gossum, A., Vermeire, S., ... Veereman, G. (2013). Profile of pediatric Crohn's disease in Belgium. Journal of Crohn's and Colitis, 7 (11), 588-98. doi:10.1016/j.crohns.2013.04.016
Peer Reviewed verified by ORBi

Haerynck, F., Mahachie John, J., Van Steen, K., Schelstraete, P., Van daele, S., Loeys, B., Van Thielen, M., De Canck, I., Nuytinck, L., & De Baets, F. (2013). Genetic variations in toll-like receptor pathway and lung function decline in Cystic fibrosis patients. Human Immunology, 74 (12), 1649-55. doi:10.1016/j.humimm.2013.08.282
Peer Reviewed verified by ORBi

Salvatore, S., Salvatoni, A., Van Steen, K., Ummarino, D., Hauser, B., & Vandenplas, Y. (2013). Behind the (impedance) baseline in children. Diseases of the Esophagus. doi:10.1111/dote.12152
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Milne, R., La Vecchia, C., Van Steen, K., Hahn, S., Buchholz, M., Costello, E., Esposito, I., Hoheisel, J. D., Lange, B., Lopez-Bigas, N., Michalski, C. W., Real, F. X., Brand, A., & Malats, N. (2013). EU Pancreas: An Integrated European Platform for Pancreas Cancer Research - from Basic Science to Clinical and Public Health Interventions for a Rare Disease. Public Health Genomics, 16 (6), 305-12. doi:10.1159/000355937
Peer Reviewed verified by ORBi

Van Lishout, F., Vens, C., Urrea, V., Calle, M. L., Wehenkel, L., & Van Steen, K. (03 December 2012). Survival analysis: finding relevant epistatic SNP pairs using Model- Based Multifactor Dimensionality Reduction [Paper presentation]. 5th International Conference of the ERCIM WG on COMPUTING & STATISTICS, Oviedo, Spain.

Bessissow, T., Lemmens, B., Ferrante, M., Bisschops, R., Van Steen, K., Geboes, K., Van Assche, G., Vermeire, S., Rutgeerts, P., & De Hertogh, G. (November 2012). Prognostic Value of Serologic and Histologic Markers on Clinical Relapse in Ulcerative Colitis Patients With Mucosal Healing. American Journal of Gastroenterology, 11 (107), 1684-92. doi:10.1038/ajg.2012.301
Peer Reviewed verified by ORBi

Li, Z., Vermeire, S., Bullens, D., Ferrante, M., Van Steen, K., Noman, M., Rutgeerts, P., Ceuppens, J. L., & Van Assche, G. (October 2012). Restoration Of B Cells Correlates With Clinical Response To Anti-Tnf Therapy [Poster presentation]. united european gastroenterology.

Li, Z., Vermeire, S., Bullens, D., Ferrante, M., Van Steen, K., Noman, M., Rutgeerts, P., Ceuppens, J. L., & Van Assche, G. (October 2012). Active Foxp3 (+) Regulatory T Cells Rather Than Other Foxp3 (+) T Cells Subsets CorrelateWith Clinical Response To Infliximab Therapy For IBD [Poster presentation]. united european gastroenterology.

Gusareva, E., & Van Steen, K. (2012). Integrating biological information in genome-wide association interaction (GWAI) studies [Paper presentation]. Capita Selecta in Complex Disease Analysis, Liege, Belgium.

Breynaert, C., Dresselaers, T., Cremer, J., Van Steen, K., Perrier, C., Vermeire, S., Rutgeerts, P., Ceuppens, J., Himmelreich, U., & Van Assche, G. (May 2012). Repeated cycles of DSS inducing a chronically relapsing inflammation: a novel model to study fibrosis using in vivo MRI T2 relaxometry [Poster presentation]. Digestive Disease Week.

De Greef, E., Mahachie John, J., Hoffman, I., Smets, F., Van Biervliet, S., Hauser, B., Paquot, I., Alliet, P., Arts, W., Dewit, O., Peeters, H., Baert, F., D'haens, G., Rahier, J.-F., Etienne, I., Bauraind, O., Van Gossum, A., Vermeire, S., Fontaine, F., ... Veereman, G. (2012). Factors determining therapeutic strategy at diagnosis and evolution of disease severity in a cohort of Belgian pediatric Crohn's disease patients (BELCRO). Gastroenterology.
Peer Reviewed verified by ORBi

Breynaert, C., Dresselaers, T., Cremer, J., Van Steen, K., Perrier, C., Vermeire, S., Rutgeerts, P., Ceuppens, J., Himmelreich, U., & Van Assche, G. (May 2012). Sequential T2 Relaxometry as a Non-Invasive Assessment of Transmural Inflammation in a Murine Model of Chronically Relapsing Colitis [Poster presentation]. Digestive Disease Week.

Gusareva, E., Mahachie John, J., Isaacs, A., & Van Steen, K. (12 March 2012). Application of mixed polygenic model to control for cryptic/genuine relatedness and population stratification [Poster presentation]. HGM 2012, Sydney, Australia.

Cleynen, I., Vazeille, E., Artieda, M., Szczypiorska, M., Bringer, M.-A., Verspaget, W., Lakatos, P., Seibold, F., Parnell, K., Weersma, R., Mahachie John, J., Morgan-Walsh, R., Staelens, D., Arijs, I., Müller, S., Tordai, A., Hommes, D., Ahmad, T., Wijmenga, C., ... Darfeuille-Michaud, A. (2012). Genetic and functional evidence for a role of CYLD in Crohn’s Disease: results from a European consortium. Journal of Crohn's and Colitis.
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Breynaert, C., Dresselaers, T., Cremer, J., Van Steen, K., Perrier, C., Vermeire, S., Rutgeerts, P., Ceuppens, J., Himmelreich, U., & Van Assche, G. (February 2012). Repeated cycles of DSS inducing a chronically relapsing inflammation: A novel model to study fibrosis using in vivo MRI T2 relaxometry [Poster presentation]. Congress of the European Crohn's and Colitis Organization.

Cleynen, I., Artieda, M., Verspaget, H., Lakatos, P., Seibold, F., Ahmad, T., Weersma, R., Arijs, I., Mahachie John, J., Müller, S., Tordai, A., Hommes, D., Parnell, K., Van Steen, K., Wijmenga, C., Rutgeerts, P., Lottaz, D., & Vermeire, S. (2012). Multiple functional variants at the 3p21 locus contribute to ulcerative colitis: Results from a European consortium. Journal of Crohn's and Colitis.
Peer Reviewed verified by ORBi

Mahachie John, J., Cattaert, T., Van Lishout, F., Gusareva, E., & Van Steen, K. (2012). Lower-Order Effects Adjustment in Quantitative Traits Model-Based Multifactor Dimensionality Reduction. PLoS ONE. doi:10.1371/journal.pone.0029594
Peer Reviewed verified by ORBi

Haerynck, F., Van Steen, K., Cattaert, T., Loeys, B., Van Daele, S., Schelstraete, P., Claes, K., Van Thielen, M., De Canck, I., Mahachie John, J., & De Baets, F. (2012). Polymorphisms in the lectin pathway genes as a possible cause of early chronic Pseudomonas aeruginosa colonization in cystic fibrosis patients. Human Immunology. doi:10.1016/j.humimm.2012.08.010
Peer Reviewed verified by ORBi

Maus, B., Génin, E., Mahachie John, J., & Van Steen, K. (2012). Inference and comparison of different genetic stratification techniques [Paper presentation]. Capita Selecta in Complex Disease Analysis (CSCDA) 2012, Liège, Belgium.

Bachert, C., Van Steen, K., Zhang, N., Holtappels, G., Cattaert, T., Maus, B., Buhl, R., Taube, C., Korn, S., Kowalski, M., Bousquet, J., & Howarth, P. (2012). Specific IgE against Staphylococcus aureus enterotoxins: An independent risk factor for asthma. Journal of Allergy and Clinical Immunology, 130 (2), 376-381.e8. doi:10.1016/j.jaci.2012.05.012
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De Greef, E., Hoffman, I., D'Haens, G., Van Biervliet, S., Smets, F., Scaillon, M., Dewit, O., Peeters, H., Paquot, I., Alliet, P., Arts, W., Hauser, B., Vermeire, S., Van Gossum, A., Rahier, J.-F., Etienne, I., Louis, E., Coche, J. C., Mahachie John, J., ... Veereman, G. (2012). Safety and cost of infliximab for the treatment of Belgian pediatric patients with Crohn's disease. Acta Gastro-Enterologica Belgica, 75 (4), 425-31.
Peer Reviewed verified by ORBi

Lødrup Carlsen, K., Roll, S., Carlsen, K.-H., Mowinckel, P., Wijga, A., Brunekreef, B., Torrent, M., Roberts, G., Arshad, H., Kull, I., Krämer, U., von Berg, A., Eller, E., Høst, A., Kuehni, C., Spycher, B., Sunyer, J., Chen, C.-M., Reich, A., ... Keil, T. (2012). Does pet ownership in infancy lead to asthma or allergy at school age? Pooled analysis of individual participant data from 11 European birth cohorts. PLoS ONE. doi:10.1371/journal.pone.0043214
Peer Reviewed verified by ORBi

De Lobel, L., Thijs, L., Kouznetsova, T., Staessens, J., & Van Steen, K. (2012). A family-based association test to detect gene-gene interactions in the presence of linkage. European Journal of Human Genetics. doi:10.1038/ejhg.2012.45
Peer Reviewed verified by ORBi

Op De Beeck, K., Maes, L., Van den Bergh, K., Derua, R., Waelkens, E., Van Steen, K., Vermeersch, P., Westhovens, R., De Vlam, K., Verschueren, P., Hooijkaas, H., Blockmans, D., & Bossuyt, X. (2012). Heterogeneous nuclear ribonucleoproteins as targets of autoantibodies in systemic rheumatic diseases. Arthritis and Rheumatism, 64 (1), 213-221. doi:10.1002/art.33327
Peer Reviewed verified by ORBi

Aschard, H., Lutz, S., Maus, B., Duell, E. J., Fingerlin, T. E., Chatterjee, N., Kraft, P., & Van Steen, K. (2012). Challenges and opportunities in genome-wide environmental interaction (GWEI) studies. Human Genetics, 131, 1591-1613. doi:10.1007/s00439-012-1192-0
Peer Reviewed verified by ORBi

De Greef, E., Hoffman, I., D'haens, G., Van Biervliet, S., Smets, F., Scaillon, M., De Wit, O., Peeters, H., Paquot, I., Alliet, P., Arts, W., Hauser, B., Vermeire, S., Van Gossum, A., Rahier, J.-F., Etienne, I., Louis, E., Coche, J. C., Mahachie John, J., ... Veereman, G. (2012). Safety And Cost Of Infliximab For The Treatment Of Belgian Pediatric Patients With Crohn’s Disease. Journal of Crohn's and Colitis.
Peer Reviewed verified by ORBi

Maus, B., Génin, E., Mahachie John, J., & Van Steen, K. (2012). Clustering of Crohn’s disease patients: Identification of sub-phenotypes and population stratification. Genetic Epidemiology, 36 (7), 729.
Peer reviewed

Vieira, M., Miyague, N., Van Steen, K., Salvatore, S., & Vandenplas, Y. (2012). Effects of domperidone on QTc interval in infants. Acta Paediatrica, 101 (5), 494-496. doi:10.1111/j.1651-2227.2012.02593.x
Peer Reviewed verified by ORBi

De Greef, E., Mahachie John, J., Hoffman, I., Smets, F., Van Biervliet, S., Scaillon, M., Hauser, B., Paquot, I., Alliet, P., Arts, W., Dewit, O., Baert, F., D'haens, G., Rahier, J.-F., Etienne, I., Bauraind, O., Van Gossum, A., Vermeire, S., Fontaine, F., ... Veereman, G. (2012). Factors determining therapeutic strategy at diagnosis and evolution of disease severity in a cohort of Belgian pediatric Crohn’s disease patients (BELCRO). Acta Gastro-Enterologica Belgica.
Peer Reviewed verified by ORBi

Van Lishout, F., Cattaert, T., Mahachie John, J., Gusareva, E., Urrea, V., Cleynen, I., Theatre, E., Charloteaux, B., Kvasz, A., Calle, M. L., Wehenkel, L., & Van Steen, K. (13 December 2011). An Efficient Algorithm to Perform Multiple Testing in Epistasis Screening [Paper presentation]. Benelux Bioinformatics Conference 2011, Luxembourg, Luxembourg.

Mahachie John, J., Cattaert, T., De Lobel, L., Van Lishout, F., Empain, A., & Van Steen, K. (2011). Comparison of genetic association strategies in the presence of rare alleles. BMC Proceedings. doi:10.1186/1753-6561-5-S9-S32
Peer Reviewed verified by ORBi

Ochsenkühn, T., Steinborn, A., Beigel, F., Mahachie John, J., Van Steen, K., Schnitzler, S., Tillack, C., Göke, B., Weidinger, M., Brand, S., & Seiderer, J. (2011). Rate of Malignancies and Infections in a Large Single Center Cohort of IBD Patients Treated With Thiopurines and Anti-TNF-Antibodies. Gut.
Peer Reviewed verified by ORBi

Mahachie John, J., Gusareva, E., Van Lishout, F., & Van Steen, K. (19 September 2011). A robustness study to investigate the performance of parametric and non-parametric tests used in Model-Based Multifactor Dimensionality Reduction Epistasis Detection [Poster presentation]. 20th Annual IGES Conference, Heidelberg, Germany.

Cattaert, T., Rial Garcia, J. A., Gusareva, E., & Van Steen, K. (19 September 2011). Comparison Of Different Methods For Detecting Gene-Gene Interactions In Case-Control Data [Poster presentation]. 20th Annual IGES Conference, Heidelberg, Germany.

Gusareva, E., & Van Steen, K. (19 September 2011). Genome-wide epistasis screening for Crohns’ disease [Poster presentation]. 20th Annual IGES Conference, Heidelberg, Germany.

Gusareva, E., Huyghe, J., & Van Steen, K. (01 August 2011). Genome-wide epistasis screening for asthma associated traits [Poster presentation]. Joint statistical Meetings, Miami Beach, Florida, United States.

Ochsenkühn, T., Steinborn, A., Beigel, F., Breiteneicher, S., Mahachie John, J., Van Steen, K., Schnitzler, F., Tillack, C., Göke, B., Weidinger, M., Brand, S., & Seiderer, J. (2011). Rate of Malignancies and Infections in a Large Single Center Cohort of IBD Patients Treated With Thiopurines and Anti-TNF-Antibodies. American Journal of Gastroenterology.
Peer Reviewed verified by ORBi

Vermeulen, N., de Beeck, K. O., Vermeire, S., Van Steen, K., Michiels, G., Ballet, V., Rutgeerts, P., & Bossuyt, X. (2011). Identification of a novel autoantigen in inflammatory bowel disease by protein microarray. Inflammatory Bowel Diseases, 17 (6), 1291-300. doi:10.1002/ibd.21508
Peer Reviewed verified by ORBi

Van Steen, K., & Sleegers, K. (2011). A report of the first biennial meeting on Capita Selecta in Complex Disease Analysis (CSCDA2010), Leuven, Belgium, August 25-27, 2010. Annals of Human Genetics, 75 (4), 554-7. doi:10.1111/j.1469-1809.2011.00659.x
Peer Reviewed verified by ORBi

Steinborn, A., Beigel, F., Breiteneicher, S., Van Steen, K., Schnitzler, F., Göke, B., Weidinger, M., Brand, S., Ochsenkühn, T., & Seiderer, J. (2011). Risk Of Malignancies In A Single Center Cohort Of IBD-Patients Treated with Immunosuppressives and Anti-TNF-antibodies. American Journal of Gastroenterology.
Peer Reviewed verified by ORBi

Mahachie John, J., Van Lishout, F., & Van Steen, K. (2011). Model-Based Multifactor Dimensionality Reduction to detect epistasis for quantitative traits in the presence of error-free and noisy data. European Journal of Human Genetics, 19, 696-703. doi:10.1038/ejhg.2011.17
Peer Reviewed verified by ORBi

Cleynen, I., Artieda, M., Szczyoiorska, M., Verspaget, W., Lakatos, L., Seibold, F., Ahmad, T., Weersma, K., Mueller, S., Tordai, A., Hommes, W., Parnell, K., Wijmenga, C., Van Steen, K., Rutgeerts, P., Lottaz, D., & Vermeire, S. (2011). The protease genes CYLD and USP40 are associated with Crohn's disease: results from a European Consortium. Gastroenterology, 140 (5), 269.
Peer Reviewed verified by ORBi

De Greef, E., Hoffman, I., Smets, F., Van Biervliet, S., Scaillon, M., Hauser, B., Paquot, I., Alliet, P., Arts, W., Dewit, O., Peeters, H., Baert, F., D'Haens, G., Rahier, J., Etienne, I., Baureind, O., Van Gossum, A., Vermeire, S., Fontaine, F., ... Veereman, G. (2011). Profile of Belgian Pediatric Crohn's Disease Patients: Presentation and diagnostic features. Journal of Crohn's and Colitis, 5 (1), 155.
Peer Reviewed verified by ORBi

Steinborn, A., Beigel, F., Breiteneicher, S., Van Steen, K., Schnitzler, F., Göke, B., Weidinger, M., Brand, S., Ochsenkühn, T., & Seiderer, J. (2011). Risk Of Malignancies In A Single Center Cohort Of IBD-Patients Treated with Immunosuppressives and Anti-TNF-antibodies. Journal of Crohn's and Colitis.
Peer Reviewed verified by ORBi

De Greef, E., Hoffman, I., Smets, F., Van Biervliet, S., Scaillon, M., Hauser, B., Paquot, I., Alliet, P., Arts, W., Dewit, O., Peeters, H., Baert, F., D'Haens, G., Rahier, J., Etienne, I., Bauraind, O., Van Gossum, A., Vermeire, S., Fontaine, F., ... Veereman, G. (2011). Profile of Belgian Pediatric Crohn's Disease Patients: Presentation and diagnostic features. Acta Gastro-Enterologica Belgica, 74, 05.
Peer Reviewed verified by ORBi

Joossens, M., Huys, G., Van Steen, K., Cnockaert, M., Vermeire, S., Rutgeerts, P., Verbeke, K., Vandamme, P., & De Preter, V. (2011). High-throughput method for comparative analysis of denaturing gradient gel electrophoresis profiles from human fecal samples reveals significant increases in two bifidobacterial species after inulin-type prebiotic intake. FEMS Microbiology Ecology, 75 (2), 343-9. doi:10.1111/j.1574-6941.2010.01008.x
Peer Reviewed verified by ORBi

Breynaert, C., Ferrante, M., Fidder, H., Van Steen, K., Noman, M., Ballet, V., Vermeire, S., Rutgeerts, P., & Van Assche, G. (2011). Tolerability of shortened infliximab infusion times in patients with inflammatory bowel diseases: a single-center cohort study. American Journal of Gastroenterology, 106 (4), 778-85. doi:10.1038/ajg.2011.61
Peer Reviewed verified by ORBi

Van Steen, K. (2011). Travelling the world of gene-gene interactions. Briefings in Bioinformatics, 13 (1), 1-19. doi:10.1093/bib/bbr012
Peer Reviewed verified by ORBi

Gevaert, P., Van Bruaene, N., Cattaert, T., Van Steen, K., Van Zele, T., Acke, F., De Ruyck, N., Blomme, K., Sousa, A. R., Marshall, R. P., & Bachert, C. (2011). Mepolizumab, a humanized anti-IL-5 mAb, as a treatment option for severe nasal polyposis. Journal of Allergy and Clinical Immunology, 128 (5), 989-995.e8. doi:10.1016/j.jaci.2011.07.056
Peer Reviewed verified by ORBi

Ziegler, A., Van Steen, K., & Wellek, S. (2011). Investigating Hardy-Weinberg equilibrium in case-control or cohort studies or meta-analysis. Breast Cancer Research and Treatment, 128 (1), 197-201. doi:10.1007/s10549-010-1295-z
Peer Reviewed verified by ORBi

Drobne, D., Bossuyt, P., Breynaert, C., Vande Casteele, N., Compernolle, G., Juergens, M., Ballet, V., Cleynen, I., Wollants, W., Van Steen, K., Gils, A., Rutgeerts, P., Vermeire, S., & Van Assche, G. (2011). Long term evolution and impact of immunomodulator cotreatment and withdrawal on infliximab on trough levels in 223 patients with Crohn's disease. Journal of Crohn's and Colitis.
Peer Reviewed verified by ORBi

Van Steen, K. (2011). Perspectives on genome-wide multi-stage family-based association studies. Statistics in Medicine, 30 (18), 2201-2221. doi:10.1002/sim.4259
Peer Reviewed verified by ORBi

Marquez, L., Shen, C., Cleynen, I., De Hertogh, G., Van Steen, K., Machiels, K., Perrier, C., Ballet, V., Organe, S., Boukerroucha, M., Henckaerts, L., Galicia, G., Rutgeerts, P., Ceuppens, J. L., & Vermeire, S. (2011). Effects of haptoglobin polymorphisms and deficiency on susceptibility to inflammatory bowel disease and on severity of murine colitis. Gut, 61 (4), 528-534. doi:10.1136/gut.2011.240978
Peer Reviewed verified by ORBi

Moens, L. N., De Rijk, P., Reumers, J., Van den Bossche, M. J. A., Glassee, W., De Zutter, S., Lenaerts, A.-S., Nordin, A., Nilsson, L.-G., Medina Castello, I., Norrback, K.-F., Goossens, D., Van Steen, K., Adolfsson, R., & Del-Favero, J. (2011). Sequencing of DISC1 pathway genes reveals increased burden of rare missense variants in schizophrenia patients from a northern Swedish population. PLoS ONE, 6 (8), 23450. doi:10.1371/journal.pone.0023450
Peer Reviewed verified by ORBi

Ochsenkühn, T., Steinborn, A., Beigel, F., Breiteneicher, S., Mahachie John, J., Van Steen, K., Schnitzler, F., Tillack, C., Göke, B., Weidinger, M., Seiderer, S., & Seiderer, J. (2011). Rate of Malignancies and Infections in a Large Single Center Cohort of IBD Patients Treated With Thiopurines and Anti-TNF-Antibodies. Journal of Crohn's and Colitis.
Peer Reviewed verified by ORBi

De Greef, E., Hoffman, I., Smets, F., Van Biervliet, S., Scaillon, M., Hauser, B., Paquot, I., Alliet, P., Arts, W., Dewit, O., Peeters, H., Baert, F., D'Haens, G., Rahier, J., Etienne, I., Bauraind, O., Van Gossum, A., Vermeire, S., Fontaine, F., ... Veereman, G. (2011). Profile of Belgian Pediatric Crohn's Disease Patients: Presentation and diagnostic features. Gastroenterology, 140 (5), 786.
Peer Reviewed verified by ORBi

Arijs, I., De Hertogh, G., Machiels, K., Van Steen, K., Lemaire, K., Schraenen, A., Van Lommel, L., Quintens, R., Van Assche, G., Vermeire, S., Schuit, F., & Rutgeerts, P. (2011). Mucosal gene expression of cell adhesion molecules, chemokines, and chemokine receptors in patients with inflammatory bowel disease before and after infliximab treatment. American Journal of Gastroenterology, 106 (4), 748-61. doi:10.1038/ajg.2011.27
Peer Reviewed verified by ORBi

Cattaert, T., Calle, L. M., Dudek, S. T., Mahachie John, J., Van Lishout, F., Urrea, V., Ritchie, M. D., & Van Steen, K. (2011). Model-Based Multifactor Dimensionality Reduction for detecting epistasis in case-control data in the presence of noise. Annals of Human Genetics, 75 (1), 78-89. doi:10.1111/j.1469-1809.2010.00604.x
Peer Reviewed verified by ORBi

Cleynen, I., Van Moerkercke, W., Vande Casteele, N., Ballet, V., Juergens, M., Breynaert, C., Drobne, D., Vandecandelaere, P., Van Gils, Van Steen, K., Noman, M., Van Assche, G., Rutgeerts, P., Segaert, S., & Vermeire, S. (2011). Anti-TNF induced skin manifestations in IBD patients: characterization and search for predisposing factors. Acta Gastro-Enterologica Belgica, 74.
Peer Reviewed verified by ORBi

Henckaerts, L., Cleynen, I., Brinar, M., Mahachie John, J., Van Steen, K., Rutgeerts, P., & Vermeire, S. (2011). Genetic variation in the autophagy gene ULK1 and risk of Crohn's disease. Inflammatory Bowel Diseases, 17 (6), 1392-1397. doi:10.1002/ibd.21486
Peer Reviewed verified by ORBi

Jurgens, M., Mahachie John, J., Cleynen, I., Schnitzler, F., Fidder, H., van Moerkercke, W., Ballet, V., Noman, M., Hoffman, I., van Assche, G., Rutgeerts, P. J., Van Steen, K., & Vermeire, S. (2011). Levels of C-reactive protein are associated with response to infliximab therapy in patients with Crohn's disease. Clinical Gastroenterology and Hepatology, 9 (5), 421-7.e1. doi:10.1016/j.cgh.2011.02.008
Peer Reviewed verified by ORBi

Schnitzler, F., Fidder, H., Boukerroucha, M., Ballet, V., Noman, M., Van Assche, G., Spitz, B., Hoffman, I., Van Steen, K., Vermeire, S., & Rutgeerts, P. (2011). Outcome of pregnancy in women with inflammatory bowel disease treated with antitumor necrosis factor therapy. Inflammatory Bowel Diseases, 17 (9), 1846-1854. doi:10.1002/ibd.21583
Peer Reviewed verified by ORBi

Arijs, I., Van Lommel, L., De Hertogh, G., Machiels, K., Lemaire, K., Van Steen, K., Van Assche, G., Vermeire, S., Schuit, F., & Rutgeerts, P. (2011). Mucosal gene expression profiling differentiates early from late ileal Crohn's disease. Acta Gastro-Enterologica Belgica.
Peer Reviewed verified by ORBi

Breynaert, C., Ferrante, F., Fidder, H., Van Steen, K., Noman, M., Ballet, V., Vermeire, S., Rutgeerts, P., & Van Assche, G. (2011). Tolerability of shortened infliximab infusion times in patients with inflammatory bowel disease: a single center cohort study. Acta Gastro-Enterologica Belgica.
Peer Reviewed verified by ORBi

De Greef, E., Hoffman, I., Smets, F., Van Biervliet, S., Scaillon, M., Hauser, B., Paquot, I., Alliet, P., Arts, W., Dewit, O., Peeters, H., Baert, F., D'Haens, G., Rahier, J., Etienne, I., Bauraind, O., Van Gossum, A., Vermeire, S., Fontaine, F., ... Veereman, G. (2011). Profile of Belgian Pediatric Crohn's Disease Patients: Associations between variables at diagnosis. Journal of Crohn's and Colitis, 5 (1), 156.
Peer Reviewed verified by ORBi

De Greef, E., Hoffman, I., Smets, F., Van Biervliet, S., Scaillon, M., Hauser, B., Paquot, I., Alliet, P., Arts, W., Dewit, O., Peeters, H., Baert, F., D'Haens, G., Rahier, J., Etienne, I., Bauraind, O., Van Gossum, A., Vermeire, S., Fontaine, F., ... Veereman, G. (2011). Profile of Belgian Pediatric Crohn's Disease Patients: Associations between variables at diagnosis. Gastroenterology, 140 (5), 787.
Peer Reviewed verified by ORBi

De Greef, E., Hoffman, I., Smets, F., Van Biervliet, S., Scaillon, M., Hauser, B., Paquot, I., Alliet, P., Arts, W., Dewit, O., Peeters, H., Baert, F., D'Haens, G., Rahier, J., Etienne, I., Bauraind, O., Van Gossum, A., Vermeire, S., Fontaine, F., ... Veereman, G. (2011). Profile of Belgian Pediatric Crohn's Disease Patients: Associations between variables at diagnosis. Acta Gastro-Enterologica Belgica, 74, 07.
Peer Reviewed verified by ORBi

Fidder, H., Van Steen, K., Van Assche, G., Rutgeerts, P., & Vermeire, S. (2010). Immortal time bias and infliximab-related mortality and malignancy incidence [letter to the editor]. Gut, 59, 416. doi:10.1136/gut.2009.204438
Peer Reviewed verified by ORBi

Fidder, H., Van Steen, K., Van Assche, G., Rutgeerts, P., & Vermeire, S. (2010). Reanalysis of death risk in long-term follow-up in infliximab patients versus controls [letter to the editor]. Gut, 59, 416.
Peer Reviewed verified by ORBi

Joossens, M., Van Steen, K., Branche, J., Sendid, B., Rutgeerts, P., Vasseur, F., Poulain, D., Broly, F., Colombel, J.-F., Vermeire, S., & Chamaillard, M. (2010). Familial aggregation and antimicrobial response dose-dependently affect the risk for Crohn's disease. Inflammatory Bowel Diseases, 16 (1), 58-67. doi:10.1002/ibd.20985
Peer Reviewed verified by ORBi

Arijs, I., Quintens, R., Lemaire, K., Van Lommel, L., Van Steen, K., De Hertogh, G., Van Assche, G., Vermeire, S., Geboes, K., Schuit, F., & Rutgeerts, P. J. (2010). Intestinal mucosal gene expression of endothelial cell adhesion molecules in patients with inflammatory bowel disease and the impact of infliximab therapy. Journal of Crohn's and Colitis.
Peer Reviewed verified by ORBi

Mahachie John, J., Roll, S., Lau, S., Lodrup Carlsen, K. C., Carlsen, K. H., Kuehni, C., Spycher, B., Torrent, M., Sunyer, J., Chen, C. M., Heinrich, J., Arshad, S. H., Roberts, G., Wijga, A. H., Kerkhof, M., Wickman, M., Kull, I., Eller, E., Kramer, U., ... Keil, T. (2010). Longitudinal study of European birth cohorts on pet ownership up to age 10 years as a risk for childhood asthma - a GA²LEN project. European Respiratory Journal. Supplement, 36 (supplement 54).
Peer Reviewed verified by ORBi

Breynaert, C., Ferrante, F., Fidder, H., Van Steen, K., Noman, M., Ballet, V., Vermeire, S., Rutgeerts, P., & Van Assche, G. (2010). Tolerability of shortened infliximab infusion times in patients with inflammatory bowel disease: a single center cohort study. Gut, 174-P0398.
Peer Reviewed verified by ORBi

Jürgens, M., Mahachie John, J., Van Steen, K., Schnitzler, F., Ballet, V., Noman, M., Hoffman, I., Van Assche, G., Rutgeerts, P., & Vermeire, S. (2010). Kinetics of C-reactive Protein (CRP) Following Maintenance Infliximab Treatment in Crohn’s disease identifies profiles of patients with better outcome. Journal of Crohn's and Colitis.
Peer Reviewed verified by ORBi

Cleynen, I., Mahachie John, J., Henckaerts, L., Van Moerkercke, W., Rutgeerts, P., Van Steen, K., & Vermeire, S. (2010). Molecular Reclassification of Crohn’s Disease by cluster analysis of genetic variants. Acta Gastro-Enterologica Belgica.
Peer Reviewed verified by ORBi

Cleynen, I., Mahachie John, J., Henckaerts, L., Van Moerkercke, W., Rutgeerts, P., Van Steen, K., & Vermeire, S. (2010). Molecular Reclassification of Crohn's Disease by Cluster Analysis of Genetic Variants. PLoS ONE, 5 (9), 12952. doi:10.1371/journal.pone.0012952
Peer Reviewed verified by ORBi

Bachert, C., Zhang, N., Holtappels, G., De Lobel, L., van Cauwenberge, P., Liu, S., Lin, P., Bousquet, J., & Van Steen, K. (2010). Presence of IL-5 and Ige-antibodies to staphylococcal enterotoxins in nasal polyps is associated with co-morbid asthma. Journal of Allergy and Clinical Immunology, 126 (5), 962-968. doi:10.1016/j.jaci.2010.07.007
Peer Reviewed verified by ORBi

Arijs, I., Quintens, R., Lemaire, K., Van Lommel, L., Van Steen, K., De Hertogh, G., Van Assche, G., Vermeire, S., Geboes, K., Schuit, F., & Rutgeerts, P. (2010). Intestinal mucosal expression of matrix metalloproteinase and ADAM genes in patients with inflammatory bowel disease and the impact of infliximab therapy. Gastroenterology, 138 (5), 677.
Peer Reviewed verified by ORBi

Cohen, R. T., Raby, B. A., Van Steen, K., Fuhlbrigge, A. L., Celedón, J. C., Rosner, B. A., Strunk, R. C., Zeiger, R. S., & Weiss, S. T. (2010). In utero smoke exposure and impaired response to inhaled corticosteroids in children with asthma. Journal of Allergy and Clinical Immunology, 126 (3), 491-497. doi:10.1016/j.jaci.2010.06.016
Peer Reviewed verified by ORBi

Calle, M. L., Urrea, V., & Van Steen, K. (2010). mbmdr: an R package for exploring gene-gene interactions associated with binary or quantitative traits. Bioinformatics, 26 (17), 2198-2199. doi:10.1093/bioinformatics/btq352
Peer Reviewed verified by ORBi

De Lobel, L., Geurts, P., Baele, G., Castro-Giner, F., Kogevinas, M., & Van Steen, K. (2010). A screening methodology based on Random Forests to improve the detection of gene-gene interactions. European Journal of Human Genetics, 18 (1127), 1132. doi:10.1038/ejhg.2010.48
Peer Reviewed verified by ORBi

Van Steen, K., & Molenberghs, G. (2010). Multicollinearity. In Chow (Ed.), Encyclopedia of Biopharmaceutical Statistics. Shein-Chung Chow [edit.].
Peer reviewed

Arijs, I., Quintens, R., Van Lommel, L., Van Steen, K., De Hertogh, G., Lemaire, K., Schraenen, A., Perrier, C., Van Assche, G., Vermeire, S., Geboes, K., Schuit, F., & Rutgeerts, P. (2010). Predictive value of epithelial gene expression profiles for response to infliximab in Crohn’s disease. Inflammatory Bowel Diseases, 16 (12), 2090-2098. doi:10.1002/ibd.21301
Peer Reviewed verified by ORBi

Cattaert, T., Urrea, V., Naj, A. C., De Lobel, L., De Wit, V., Fu, M., Mahachie John, J., Shen, H. Q., Calle, M. L., Ritchie, M. D., Edwards, T. L., & Van Steen, K. (2010). FAM-MDR: A Flexible Family-Based Multifactor Dimensionality Reduction Technique to Detect Epistasis Using Related Individuals. PLoS ONE, 5 (4). doi:10.1371/journal.pone.0010304
Peer Reviewed verified by ORBi

Arijs, I., Quintens, R., Lemaire, K., Van Lommel, L., Van Steen, K., De Hertogh, G., Van Assche, G., Vermeir, S., Geboes, K., Schuit, F., & Rutgeerts, P. (2010). The impact of infliximab therapy on intestinal mucosal gene expression of endothelial cell adhesion molecules in patients with inflammatory bowel disease. Gastroenterology, 138 (5 Suppl I), 677.
Peer Reviewed verified by ORBi

Arijs, I., Quintens, R., Lemaire, K., Van Lommel, L., Van Steen, K., De Hertogh, G., Van Assche, G., Vermeire, S., Geboes, K., Schuit, F., & Rutgeerts, P. J. (2010). Intestinal mucosal gene expression of endothelial cell adhesion molecules in patients with inflammatory bowel disease before and after first infliximab treatment. Acta Gastro-Enterologica Belgica.
Peer Reviewed verified by ORBi

Jürgens, M., Mahachie John, J., Cleynen, I., Schnitzler, F., Ballet, V., Noman, M., Hoffman, I., Van Assche, G., Rutgeerts, P., Van Steen, K., & Vermeire, S. (2010). Kinetics of C-Reactive Protein (CRP) following maintenance infliximab treatment in Crohn's disease identifies profiles of patients with better outcome. Gastroenterology, 138 (5 (Suppl I)), 686.
Peer Reviewed verified by ORBi

Schnitzler, F., Fidder, H., Ferrante, M., Noman, M., Arijs, I., Van Assche, G., Hoffman, I., Van Steen, K., Vermeire, S., & Rutgeerts, P. (2009). Mucosal Healing Predicts Long-term Outcome of Maintenance Therapy with Infliximab in Crohn's Disease. Inflammatory Bowel Diseases, 15 (9), 1295-1301. doi:10.1002/ibd.20927
Peer Reviewed verified by ORBi

Henckaerts, L., Van Steen, K., Verstreken, I., Cleynen, I., Franke, A., Schreiber, S., Rutgeerts, P., & Vermeire, S. (2009). Genetic risk profiling and prediction of disease course in Crohn's disease patients. Clinical Gastroenterology and Hepatology, 7 (9), 972-980.e2. doi:10.1016/j.cgh.2009.05.001
Peer Reviewed verified by ORBi

Arijs, I., Lemaire, K., Quintens, R., Van Lommel, L., Perrier, C., Van Steen, K., De Hertogh, G., Van Assche, G., Vermeire, S., Geboes, K., Schuit, F., & Rutgeerts, P. (2009). The impact of infliximab therapy on intestinal mucosal expression of matrix metalloproteinase and ADAM genes in patients with inflammatory bowel disease. Gut.
Peer Reviewed verified by ORBi

Arijs, I., Quintens, R., Van Lommel, L., Van Steen, K., De Hertogh, G., Van Assche, G., vermeire, S., Geboes, K., Schuit, F., & Rutgeerts, P. (2009). The impact of infliximab therapy on colonic mucosal expression of barrier genes in patients with inflammatory bowel disease. Acta Gastro-Enterologica Belgica.
Peer Reviewed verified by ORBi

Arijs, I., Van Lommel, L., Van Steen, K., De Hertogh, G., Quintens, R., Van Assche, G., Vermeire, S., Geboes, K., Schuit, F., & Rutgeerts, P. (2009). Colonic mucosal expression of barrier genes in patients with inflammatory bowel disease before and after first infliximab treatmen. Acta Gastro-Enterologica Belgica.
Peer Reviewed verified by ORBi

Cattaert, T., De Wit, V., Mahachie John, J., & Van Steen, K. (2009). Selecting multiple epistatic models using MB-MDR. In Conference Abstract Book.
Peer reviewed

Arijs, I., Van Lommel, L., Van Steen, K., De Hertogh, G., Van Assche, G., Vermeire, S., Geboes, K., Schuit, F., & Rutgeerts, P. (2009). Colonic mucosal expression of barrier genes in patients with inflammatory bowel disease before and after first infliximab treatment. Journal of Crohn's and Colitis, 3 (1), 3.
Peer Reviewed verified by ORBi

Arijs, I., Quintens, R., Van Lommel, L., Van Steen, K., De Hertogh, G., Van Assche, G., Vermeire, S., Geboes, K., Schuit, F., & Rutgeerts, P. (2009). The impact of infliximab therapy on colonic mucosal expression of barrier genes in patients with inflammatory bowel disease. Gastroenterology, 136, 1190.
Peer Reviewed verified by ORBi

Cleynen, I., Van Moerkercke, W., Mahachie John, J., Rutgeerts, P., Van Steen, K., & Vermeire, S. (2009). Cluster analysis of genetic variants enables reclassification of Crohn’s disease at the molecular level. Gut.
Peer Reviewed verified by ORBi

Jürgens, M., Schnitzler, F., Van Steen, K., Mahachie John, J., Ballet, V., Noman, M., Hoffman, I., Van Assche, G., Rutgeerts, P., & Vermeire, S. (2009). Predictive Value of C-Reactive Protein Level Changes On the Long Term Outcome of Infliximab in Crohn's Disease. Gastroenterology, 136 (5), 171.
Peer Reviewed verified by ORBi

Arijs, I., Li, K., Toedter, G., Quintens, R., Van Lommel, L., Van Steen, K., Leemans, P., De Hertogh, G., Lemaire, K., Ferrante, M., Schnitzler, F., Thorrez, L., Ma, K., Song, X. Y., Marano, C., Van Assche, G., Vermeire, S., Geboes, K., Schuit, F., ... Rutgeerts, P. (2009). Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis. Gut, 58 (12), 1612-9. doi:10.1136/gut.2009.178665
Peer Reviewed verified by ORBi

Schnitzler, F., Fidder, H., Ferrante, M., Noman, M., Arijs, I., Van Assche, G., Hoffman, I., Van Steen, K., Vermeire, S., & Rutgeerts, P. (2009). Long-term outcome of treatment with infliximab in 614 patients with Crohn's disease: results from a single-centre cohort. Gut, 58 (4), 492-500. doi:10.1136/gut.2008.155812
Peer Reviewed verified by ORBi

Ripatti, S., Becker, T., Bickeboller, H., Dominicus, A., Fischer, C., Humphreys, K., Jonasdottir, G., Moreau, Y., Olsson, M., Ploner, A., Sheehan, N., Van Steen, K., Baur, M., van Duijn, C., & Palmgren, J. (2009). GENESTAT: an information portal for design and analysis of genetic association studies. European Journal of Human Genetics, 17 (4), 533-6. doi:10.1038/ejhg.2008.216
Peer Reviewed verified by ORBi

Arijs, I., De Hertogh, G., Lemaire, K., Quintens, R., Van Lommel, L., Van Steen, K., Leemans, P., Cleynen, I., Van Assche, G., Vermeire, S., Geboes, K., Schuit, F., & Rutgeerts, P. (2009). Mucosal Gene Expression of Antimicrobial Peptides in Inflammatory Bowel Disease Before and After First Infliximab Treatment. PLoS ONE, 4 (11), 7984. doi:10.1371/journal.pone.0007984
Peer Reviewed verified by ORBi

Cleynen, I., Mahachie John, J., Henkaerts, L., Van Moerkercke, Rutgeerts, P., Van Steen, K., & Vermeire, S. (2009). Molecular Reclassification of Crohn’s Disease by cluster analysis of genetic variants. Gut.
Peer Reviewed verified by ORBi

Raby, B. A., Van Steen, K., Lasky-Su, J., Tantisira, K., Kaplan, F., & Weiss, S. T. (2009). Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma. Respiratory Research, 10, 67. doi:10.1186/1465-9921-10-67
Peer Reviewed verified by ORBi

Vanbillemont, G., Bogaert, V., De Bacquer, D., Lapauw, B., Goemaere, S., Toye, K., Van Steen, K., Taes, Y., & Kaufman, J. M. (2009). Polymorphisms of the SHBG gene contribute to the interindividual variation of sex steroid hormone blood levels in young, middle-aged and elderly men. Clinical Endocrinology, 70 (2), 303-310. doi:10.1111/j.1365-2265.2008.03365.x
Peer Reviewed verified by ORBi

Bogaert, V., Vanbillemont, G., Taes, Y., De Bacquer, D., Deschepper, E., Van Steen, K., & Kaufman, J. M. (2009). Small effect of the androgen receptor gene GGN repeat polymorphism on serum testosterone levels in healthy men. European Journal of Endocrinology, 161 (1), 171-7. doi:10.1530/EJE-09-0123
Peer Reviewed verified by ORBi

Henckaerts, L., Nielsen, K. R., Steffensen, R., Van Steen, K., Mathieu, C., Giulietti, A., Wouters, P. J., Milants, I., Vanhorebeek, I., Langouche, L., Vermeire, S., Rutgeerts, P., Thiel, S., Wilmer, A., Hansen, T. K., & Van den Berghe, G. (2009). Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit. Critical Care Medicine, 37 (1), 192-201, e1-3. doi:10.1097/CCM.0b013e31819263d8
Peer Reviewed verified by ORBi

Jürgens, M., Schnitzler, F., Van Steen, K., Mahachie John, J., Ballet, V., Noman, M., Hoffman, I., Van Assche, G., Rutgeerts, P., & Vermeire, S. (2009). Predictive Value of C-Reactive Protein Level Changes On the Long Term Outcome of Infliximab in Crohn's Disease. Acta Gastro-Enterologica Belgica.
Peer Reviewed verified by ORBi

De Lobel, L., De Meyer, H., Thijs, L., Kouznetsova, T., Staessen, J., & Van Steen, K. (2009). A Family-Based Association Test to Detect Gene-Gene Interactions in the Presence of Linkage. Genetic Epidemiology, 33 (8), 771 A68.
Peer Reviewed verified by ORBi

Arijs, I., Van Lommel, L., Van Steen, K., De Hertogh, G., Quintens, R., Van Assche, G., Vermeire, S., Geboes, K., Schuit, F., & Rutgeerts, P. (2009). TECK and MADCAM-1 mucosal expression in active IBD: the effect of infliximab therapy. Gastroenterology, 136, 1180.
Peer Reviewed verified by ORBi

De Lobel, L., De Meyer, H., Thijs, L., Kouznetsova, T., Staessen, J., & Van Steen, K. (2008). A Family-based Association Test for Quantitative Traits to Detect Gene-Gene Interactions. Genetic Epidemiology, 32 (7), 686-686.
Peer Reviewed verified by ORBi

Arijs, I., Van Lommel, L., Van Steen, K., De Hertogh, G., Ferrante, M., Joossens, M., Geboes, K., Van Assche, G., Vermeire, S., Schuit, F., & Rutgeerts, P. (2008). Mucosal gene signatures to predict response to infliximab in patients with inflammatory bowel disease. Acta Gastro-Enterologica Belgica.
Peer Reviewed verified by ORBi

Joossens, M., De Preter, V., Van Steen, K., Vermeulen, N., Huys, G., Verbeke, K., Vandamme, P., Rutgeerts, P., & Vermeire, S. (2008). Long term stability of gut microbiota in Crohn’s disease patients compared to healthy relatives. Acta Gastro-Enterologica Belgica, 71, 73.
Peer Reviewed verified by ORBi

De Lobel, L., De Meyer, H., Baele, G., Kogevinas, M., & Van Steen, K. (2008). Alternative methods to detect gene-gene interactions. In Conference Abstract Book (pp. 2474).
Peer reviewed

Arijs, I., Van Lommel, L., Van Steen, K., De Hertogh, G., Ferrante, M., Joossens, M., Geboes, K., Van Assche, G., Vermeire, S., Schuit, F., & Rutgeerts, P. (2008). Mucosal gene signatures to predict response to infliximab in patients with inflammatory bowel disease. Gastroenterology, 134, 117.
Peer Reviewed verified by ORBi

Bogaert, V., Taes, Y., Konings, P., Van Steen, K., De Bacquer, D., Goemaere, S., Zmierczak, H., Crabbe, P., & Kaufman, J.-M. (2008). Heritability of blood concentrations of sex-steroids in relation to body composition in young adult male siblings. Clinical Endocrinology, 69 (1), 129-35. doi:10.1111/j.1365-2265.2008.03173.x
Peer Reviewed verified by ORBi

Henckaerts, L., Cleynen, I., Joossens, M., Van Steen, K., Claes, K., Rutgeerts, P., & Vermeire, S. (2008). Genetic markers and the risk of complicated disease behaviour in Crohn's disease patients. Gastroenterology, 134 (4), 349-A349.
Peer Reviewed verified by ORBi

Calle, M. L., Urrea, V., Vellalta, G., Malats, N., & Van Steen, K. (2008). Model-Based Multifactor Dimensionality Reduction for detecting interactions in high-dimensional genomic data. (Technical Report No. 24). Department of Systems Biology, Universitat de Vic. https://orbi.uliege.be/handle/2268/144460

Joossens, M., De Preter, V., Van Steen, K., Vermeulen, N., Huys, G., Verbeke, K., Vandamme, P., & Rutgeerts, P. (2008). Stability Of Gut Microbiota Over Time In Crohn's Disease Patients Compared To Healthy Relatives. Journal of Crohn's and Colitis, 2 (1), 94.
Peer Reviewed verified by ORBi

Arijs, I., Van Lommel, L., Van Steen, K., De Hertogh, G., Ferrante, M., Joossens, M., Geboes, K., Van Assche, G., Vermeire, S., Schuit, F., & Rutgeerts, P. (2008). Mucosal gene signatures to predict response to infliximab in patients with inflammatory bowel disease. Journal of Crohn's and Colitis, 2 (1), 64.
Peer Reviewed verified by ORBi

Van Steen, K., Calle, M., Urrea, V., & Malats, N. (2008). FAM-MDR: a flexible method of multifactor dimensionality reduction for high-order interaction detection. In Conference Abstract book (pp. 2473).
Peer reviewed

Calle, M. L., Urrea, V., Malats, N., & Van Steen, K. (2008). Improving strategies for detecting genetic patterns of disease susceptibility in association studies. Statistics in Medicine, 27 (30), 6532-6546. doi:10.1002/sim.3431
Peer Reviewed verified by ORBi

Arijs, I., Quintens, R., Van Lommel, L., Van Steen, K., De Hertogh, G., Van Assche, G., Vermeire, S., Geboes, K., Schuit, F., & Rutgeerts, P. (2008). Effect of infliximab treatment on colonic mucosal gene expression profiles in patients with inflammatory bowel disease. Gut, 57 (Suppl II), 39.
Peer Reviewed verified by ORBi

Arijs, I., Lemaire, K., Quintens, R., Van Lommel, L., Leemans, P., Van Steen, K., De Hertogh, G., Van Assche, G., Vermeire, S., Geboes, K., Schuit, F., & Rutgeerts, P. (2008). Gene expression of antimicrobial peptides in colonic mucosa of patients with inflammatory bowel disease before and after first infliximab treatment. Gut, 57 (Suppl II), 102-A103.
Peer reviewed

Joossens, M., De Preter, V., Van Steen, K., Vermeulen, N., Huys, G., Verbeke, K., Van Damme, P., Rutgeerts, P., & Vermeire, S. (2008). Stability of gut microbiota over time in Crohn's disease patients compared to healthy relatives. Gastroenterology, 134 (4), 653-A653.
Peer Reviewed verified by ORBi

Castro-Giner, F., Kogevinas, M., Maechler, M., de Cid, R., Van Steen, K., Imboden, M., Schindler, C., Berger, W., Gonzalez, J. R., Franklin, K. A., Janson, C., Jarvis, D., Omenaas, I., Burney, R., Rochat, T., Estivill, X., Anto, J. M., Wjst, M., & Probst-Hensch, N. M. (2008). TNFA-3086 > A in two international population-based cohorts and risk of asthma. European Respiratory Journal, 32 (2), 350-361. doi:10.1183/09031936.00155607
Peer Reviewed verified by ORBi

Cleynen, I., Claes, B., Nuytten, H., Van Steen, K., Henckaerts, L., Noman, N., Fidder, H., Cuppens, H., Lambrechts, D., & Rutgeerts, P. (2008). Development of psoriasiform skin lesions under anti-TNF therapy: a genetic link? In Conference Abstract Book.
Peer reviewed

Ferrante, M., Vermeire, S., Fidder, H., Schnitzler, F., Noman, M., Van Assche, G., De Hertogh, G., Hoffman, I., D'Hoore, A., Van Steen, K., Geboes, K., Penninckx, F., & Rutgeerts, P. (2008). Long-term outcome after infliximab for refractory ulcerative colitis. Journal of Crohn's and Colitis, 2 (3), 219-225. doi:10.1016/j.crohns.2008.03.004
Peer Reviewed verified by ORBi

Ferrante, M., Vermeire, S., Schnitzler, F., Noman, M., Van Assche, G., Arijs, I., Joossens, M., Cleynen, I., Vermeulen, N., Hoffman, I., Van Steen, K., & Rutgeerts, P. (2008). Long-term efficacy of infliximab and colectomy-free survival in outpatients with refractory ulcerative colitis. Journal of Crohn's and Colitis, 2 (1), 3.
Peer Reviewed verified by ORBi

Arijs, I., Van Lommel, L., Van Steen, K., De Hertogh, G., Quintens, R., Lemaire, K., Joossens, M., Schuit, F., Geboes, K., Van Assche, G., Vermeire, S., & Rutgeerts, P. (2008). Microarray study of mucosal antimicrobial peptides in patients with inflammatory bowel disease before and after infliximab treatment. Journal of Crohn's and Colitis, 2 (1), 60.
Peer Reviewed verified by ORBi

Arijs, I., Van Lommel, L., Van Steen, K., De Hertogh, G., Quintens, R., Lemaire, K., Joossens, Van Assche, G., Vermeire, S., Geboes, K., Schuit, F., & Rutgeerts, P. (2008). Microarray study of mucosal antimicrobial peptides in patients with inflammatory bowel disease before and after first infliximab treatment. Gastroenterology, 134, 2043.
Peer Reviewed verified by ORBi

Henckaerts, L., Verstreken, I., Van Steen, K., Vlietinck, R., Rutgeerts, P., & Vermeire, S. (2007). Genetic markers and the risk of complicated disease behaviour in Crohn’s disease patients. Gut.
Peer Reviewed verified by ORBi

Molenberghs, G., Beunkens, C., Thijs, H., Jansen, I., Verbeke, G., Kenward, M., & Van Steen, K. (2007). Analysis of incomplete data. In SAS System for Clinical Trials II.

Roll, S., Keil, T., Eller, E., Bindslev-Jensen, C., Kraemer, U., Chen, C., von Berg, A., Smit, H., Wijga, A., Carlsen, K. L., Carlsen, K., Wickman, M., Kull, I., Mommers, M., Thijs, C., Forastiero, F., Porta, D., Fantin, I., Bravi, F., ... Heinrich, J. (2007). Pet ownership in eight European birth cohorts - results of a GA(2)LEN initiative. Allergy, 62, 67-67.
Peer Reviewed verified by ORBi

Arijs, I., Van lommel, L., Van Steen, K., De hertogh, G., Schuit, F., Geboes, K., Van assche, G., Vermeire, S., & Rutgeerts, P. J. (2007). Gene expression profiling to predict the response of infliximab in patients with UC. Gastroenterology, 132 (4), 174-A174.
Peer Reviewed verified by ORBi

Pierik, M., Van Steen, K., Joossens, M., Rutgeerts, P. J., & Vermeire, S. (2007). Mixed IBD families: A distinct entity within IBD. Gastroenterology, 132 (4), 450-A450.
Peer Reviewed verified by ORBi

Efficace, F., Bottomley, A., Coens, C., Van Steen, K., Conroy, T., Schoeffski, P., Schmoll, H., Van Cutsem, E., & Koehne, C.-H. (2007). Does a patient's self-reported health-related quality of life predict survival beyond key biomedical data in advanced colorectal cancer? (vol 42, pg 42, 2006). European Journal of Cancer, 43 (3), 633-633. doi:10.1016/j.ejca.2005.07.040
Peer Reviewed verified by ORBi

Joossens, M., Vanhoutte, T., De Preter, V., Van Steen, K., Henckaerts, L., Huys, G., Verbeke, K., Vandamme, P., Rutgeerts, P., & Vermeire, S. (2007). Faecal bacterial DGGE profiles of Crohn’s disease patients are different from those of their healthy first degree relatives and matched healthy controls. Acta Gastro-Enterologica Belgica.
Peer Reviewed verified by ORBi

Arijs, I., Van Lommel, L., Van Steen, K., De Hertogh, G., Van Assche, G., Vermeire, S., Geboes, K., Schuit, F., & Rutgeerts, P. (2007). Gene expression profiling to predict the response of infliximab in patients with UC. Gut, 56 (Suppl III), 19.
Peer Reviewed verified by ORBi

Joossens, M., Vanhoutte, T., De Preter, V., Van Steen, K., Henckaerts, L., Arijs, I., Huys, G., Verbeke, K., Van Damme, P., Rutgeerts, P., & Vermeire, S. (2007). Faecal bacterial dgge profiles of Crohn's disease patients are different from those of their healthy first degree relatives and matched healthy controls. Gastroenterology, 132 (4), 704-A704.
Peer Reviewed verified by ORBi

Henckaerts, L., Verstreken, I., Van Steen, K., Vlietinck, R., Rutgeerts, P., & Vermeire, S. (2007). Genetic markers and the risk of complicated disease behaviour in Crohn's disease patients. Journal of Crohn's and Colitis, 1 (1), 41-42.
Peer Reviewed verified by ORBi

Joossens, M., Vanhoutte, T., De preter, V., Van Steen, K., Henckaerts, L., Arijs, I., Huys, G., Verbeke, K., Vandamme, P., Rutgeerts, P., & Vermeire, S. (2007). Faecal bacterial dgge profiles of Crohn's disease patients are different from those of their healthy first degree relatives and matched healthy controls. Journal of Crohn's and Colitis, 1 (1), 55.
Peer Reviewed verified by ORBi

Joossens, M., De Preter, V., Vanhoutte, T., Van Steen, K., Huys, G., Verbeke, K., Vandamme, P., Rutgeerts, P., & Vermeire, S. (2007). Faecal bacterial molecular profiles of Crohn’s disease patients differ from their healthy relatives and matched healthy controls. Gut, 56 (Suppl III), 5.
Peer Reviewed verified by ORBi

Van Steen, K., Laird, N. M., Markel, P., & Molenberghs, G. (2007). Approaches to handling incomplete data in family-based association testing. Annals of Human Genetics, 71 (Pt 2), 141-51. doi:10.1111/j.1469-1809.2006.00325.x
Peer Reviewed verified by ORBi

Henckaerts, L., Verstreken, I., Van Steen, K., Vlietinck, R., Rutgeerts, P., & Vermeire, S. (2007). Genetic markers and the risk of complicated disease behaviour in Crohn's disease patients. Gastroenterology, 132 (4), 17-A18.
Peer Reviewed verified by ORBi

Ferrante, M., Henckaerts, L., Joossens, M., Pierik, M., Joossens, S., Dotan, N., Norman, G., Altstock, R., Van Steen, K., Rutgeerts, P., Van Assche, G., & Vermeire, S. (2007). New serological markers in inflammatory bowel disease are associated with complicated disease behavior. Gut, 56 (10), 1394-1403. doi:10.1136/gut.2006.108043
Peer Reviewed verified by ORBi

Arijs, I., Van Lommel, L., Van Steen, K., De Hertogh, G., Schuit, F., Geboes, K., Van Assche, G., Vermeire, S., & Rutgeerts, P. J. (2007). Gene expression profiling to predict the response of infliximab in patients with UC. Journal of Crohn's and Colitis, 1 (1), 34.
Peer Reviewed verified by ORBi

Raby, B. A., Hwang, E. S., Van Steen, K., Tantisira, K., Peng, S., Litonjua, A., Lazarus, R., Giallourakis, C., Rioux, J. D., Sparrow, D., Silverman, E. K., Glimcher, L. H., & Weiss, S. T. (2006). T-bet polymorphisms are associated with asthma and airway hyperresponsiveness. American Journal of Respiratory and Critical Care Medicine, 173 (1), 64-70. doi:10.1164/rccm.200503-505OC
Peer Reviewed verified by ORBi

Efficace, F., Bottomley, A., Coens, C., Van Steen, K., Conroy, T., Schoffski, P., Schmoll, H., Van Cutsem, E., & Kohne, C. H. (2006). Does a patient's self-reported health-related quality of life predict survival beyond key biomedical data in advanced colorectal cancer? European Journal of Cancer, 42 (1), 42-9. doi:10.1016/j.ejca.2005.07.025
Peer Reviewed verified by ORBi

Pierik, M., Joossens, S., Van Steen, K., Van Schuerbeek, N., Vlietinck, R., Rutgeerts, P., & Vermeire, S. (2006). Toll-like receptor-1,-2, and-6 polymorphisms influence disease extension in inflammatory bowel diseases. Inflammatory Bowel Diseases, 12 (1), 1-8. doi:10.1097/01.MIB.0000195389.11645.ab
Peer Reviewed verified by ORBi

Raby, B. A., Van Steen, K., Lazarus, R., Celedon, J. C., Silverman, E. K., & Weiss, S. T. (2006). Eotaxin polymorphisms and serum total IgE levels in children with asthma. Journal of Allergy and Clinical Immunology, 117 (2), 298-305. doi:10.1016/j.jaci.2005.10.041
Peer Reviewed verified by ORBi

Van Ranst, M., Joossens, M., Joossens, S., Van Steen, K., Pierik, M., Vermeire, S., & Rutgeerts, P. (2005). Crohn's disease and month of birth. Inflammatory Bowel Diseases, 11 (6), 597-9. doi:10.1097/01.MIB.0000163697.34592.d4
Peer Reviewed verified by ORBi

Van Steen, K., & Lange, C. (2005). PBAT: a comprehensive software package for genome-wide association analysis of complex family-based studies. Human Genomics, 2 (1), 67-9. doi:10.1186/1479-7364-2-1-67
Peer Reviewed verified by ORBi

Van Steen, K., McQueen, M. B., Herbert, A., Rosenow, C., Silverman, E. K., Laird, N. M., Weiss, S. T., & Lange, C. (2005). Genomic screening in family-based association testing and the multiple testing problem. Nature Genetics, 28, 164.
Peer Reviewed verified by ORBi

Van Steen, K., McQueen, M. B., Herbert, A., Raby, B., Lyon, H., DeMeo, D. L., Murphy, A., Su, J., Datta, S., Rosenow, C., Christman, M., Silverman, E. K., Laird, N. M., Weiss, S. T., & Lange, C. (2005). Genomic screening and replication using the same data set in family-based association testing. Nature Genetics, 37 (7), 683-691. doi:10.1038/ng1582
Peer Reviewed verified by ORBi

Bottomley, A., Efficace, F., Stuppe, R., Van Steen, K., Coens, C., Osoba, D., van Den Bent, M., Mason, W., Cairncross, G., Eisenhauer, E., Wong, R., Villa, S., Mirimanoff, R., Reni, M., & Taphoorn, M. J. (2005). A bootstrap model averaging technique to investigate the prognostic value for survival of quality of life information. Quality of Life Research, 14 (9), 2136 (abs 1022.
Peer Reviewed verified by ORBi

Bottomley, A., Taphoorn, M., Coens, C., Osoba, D., Van Steen, K., Efficace, F., van Den Bent, M., Baumert, B., & Mason, W. (2005). Predicting survival using health related quality of life scores in glioblastoma cancers: Findings from an international phase III randomised controlled trial. Journal of Clinical Oncology, 23 (16S), 9601.
Peer Reviewed verified by ORBi

Molenberghs, G., Beunkens, C., Jansen, I., Thijs, H., Verbeke, G., Kenward, M., & Van Steen, K. (2005). Analysis of incomplete data. In 'SAS System for Clinical Trials II.

Efficace, F., Bottomley, A., Coens, C., Van Steen, K., Conroy, T., Schöffski, P., Schmoll, H., Van Cutsem, E., & Köhne, C. H. (2005). The prognostic value of health related quality of life in colorectal cancer patients: A multivariate analysis using a bootstrap model-averaging approach. Quality of Life Research, 14 (9), 2137 (abs 1030.
Peer Reviewed verified by ORBi

Lange, C., Van Steen, K., McQueen, M., Herbert, A., Raby, B., Lyon, H., DeMeo, D., Murphy, A., Su, J., Datta, S., Rosenow, C., Christman, M., Silverman, E. K., Laird, N. M., & Weiss, S. T. (2005). Genomic screening and replication in one data set in family-based association testing. In Conference Abstract Book (pp. 2370).
Peer reviewed

Celedon, J. C., Van Steen, K., Lange, C., Raby, B., Tantisira, K., Silverman, E., & Weiss, S. T. (2005). Genetic predictors of asthma exacerbations among children in the childhood asthma management program. In Conference Abstract Book (pp. 1662).
Peer reviewed

Moerkerke, B., Goetghebeur, E., Van Steen, K., Vanbelle, S., & Cocquyt, V. (2005). Permutation based methods for comparing quality of life between observed treatments. Statistics in Medicine, 24 (24), 4055-66. doi:10.1002/sim.2395
Peer Reviewed verified by ORBi

McQueen, M. B., Devlin, B., Faraone, S. V., Nimgaonkar, V. L., Sklar, P., Smoller, J. W., Abou Jamra, R., Albus, M., Bacanu, S. A., Baron, M., Barrett, T. B., Berrettini, W., Blacker, D., Byerley, W., Cichon, S., Coryell, W., Craddock, N., Daly, M. J., Depaulo, J. R., ... Laird, N. M. (2005). Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. American Journal of Human Genetics, 77 (4), 582-95. doi:10.1086/491603
Peer Reviewed verified by ORBi

McQueen, M. B., Murphy, A., Kraft, P., Su, J., Lazarus, R., Laird, N. M., Lange, C., & Van Steen, K. (2005). Comparison of linkage and association strategies for quantitative traits using the COGA dataset. BMC Genetics, 6 (Suppl I), 96. doi:10.1186/1471-2156-6-S1-S96
Peer Reviewed verified by ORBi

Raby, B. A., Van Steen, K., Celedon, J. C., Litonjua, A. A., Lange, C., & Weiss, S. T. (2005). Paternal history of asthma and airway responsiveness in children with asthma. American Journal of Respiratory and Critical Care Medicine, 172 (5), 552-8. doi:10.1164/rccm.200501-010OC
Peer Reviewed verified by ORBi

Laird, N. M., Kraft, P., Lange, C., & Van Steen, K. (2005). Testing for association in genetic studies. In E. Silverman, S. D. Shapiro, D. A. Lomas, ... S. T. Weiss, Respiratory Genetics (pp. 27-46). Edward Arnold.

Murphy, A., McGueen, M. B., Su, J., Kraft, P., Lazarus, R., Laird, N. M., Lange, C., & Van Steen, K. (2005). Genomic screening in family-based association testing. BMC Genetics, 6. doi:10.1186/1471-2156-6-S1-S115
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Van Steen, K., Raby, B., Molenberghs, G., Thijs, H., De Wit, & Peeters, M. (2005). An equivalence test for comparing DNA sequences. Pharmaceutical Statistics, 4 (3), 203-214. doi:10.1002/pst.182
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Bottomley, A., Smit, E., Efficace, F., Schramel, E., Smit, H. J., Gaafar, R., Biesma, B., Lianes, P., Van Steen, K., Coens, C., & Van Meerbeeck, J. (2005). Non-small cell lung cancer and health-related quality of life (HRQOL): Is baseline HRQOL of prognostic value for survival? Quality of Life Research, 14 (9), 2050 (abs 1013.
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Efficace, F., Bottomley, A., Coens, C., Van Steen, K., Conroy, T., & Köhne, C. H. (2005). The value of patient-reported symptoms as prognostic factors for survival in advanced colorectal cancer. Journal of Clinical Oncology, 23 (16S), 267.
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Van Steen, K., Tahri, N., & Molenberghs, G. (2004). Introducing the multivariate dale model in population-based genetic association studies. Biometrical Journal, 46 (2), 187-202. doi:10.1002/bimj.200310016
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Franchimont, D., Vermeire, S., El Housni, H., Pierik, M., Van Steen, K., Gustot, T., Quertinmont, E., Abramowicz, M., Van Gossum, A., Deviere, J., & Rutgeerts, P. (2004). Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis. Gut, 53 (7), 987-992. doi:10.1136/gut.2003.030205
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Esters, N., Pierik, M., Van Steen, K., Vermeire, S., Claessens, G., Joossens, S., Vlietinck, R., & Rutgeerts, P. (2004). Transmission of CARD15 (NOD2) variants within families of patients with inflammatory bowel disease. American Journal of Gastroenterology, 99 (2), 299-305. doi:10.1111/j.1572-0241.2004.04040.x
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Joossens, S., Vermeire, S., Van Steen, K., Godefridis, G., Claessens, G., Pierik, M., Hietinck, R., Aerts, R., Rutgeerts, P., & Bossuyt, X. (2004). Pancreatic autoantibodies in inflammatory bowel disease. Inflammatory Bowel Diseases, 10 (6), 771-777. doi:10.1097/00054725-200411000-00012
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Pierik, M., Vermeire, S., Van Steen, K., Joossens, S., Claessens, G., Vlietinck, R., & Rutgeerts, P. (2004). Tumour necrosis factor- receptor 1 and 2 polymorhpisms in inflammatory bowel disease and their association with response to infliximab. Alimentary Pharmacology and Therapeutics, 20, 303-310. doi:10.1111/j.1365-2036.2004.01946.x
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Van Steen, K., McQueen, M., Herbert, A., Laird, N. M., Raby, B., Lyon, H., Su, J., Datta, S., Rosenow, C., Silverman, E. K., Weiss, S. T., & Lange, C. (2004). Genomic screening in family-based association testing. Genetic Epidemiology, 27, 300 A142.
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Efficace, F., Therasse, P., Piccart, M. J., Coens, C., Van Steen, K., Welnicka-Jaskiewicz, M., Cufer, T., Dyczka, J., Lichinitser, M., Shepherd, L., de Haes, H., Sprangers, M. A., & Bottomley, A. (2004). Health-related quality of life parameters as prognostic factors in a nonmetastatic breast cancer population: An international multicenter study. Journal of Clinical Oncology, 22 (16), 3381-3388. doi:10.1200/JCO.2004.02.060
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Vermeire, S., Rutgeerts, P., Van Steen, K., Joossens, S., Claessens, G., Pierik, M., Peeters, M., & Vlietinck, R. (2004). Genome wide scan in a Flemish inflammatory bowel disease population: support for the IBD4 locus, population heterogeneity, and epistasis. Gut, 53 (7), 980-986. doi:10.1136/gut.2003.034033
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Lange, C., Van Steen, K., Andrew, T., Lyon, H., Demeo, D. L., Raby, B., Murphy, A., Silverman, E. K., Macgregor, A., Weiss, S. T., & Laird, N. M. (2004). A family-based association test for repeatedly measured quantitative traits adjusting for unknown environmental and/or polygenic effects. Statistical Applications in Genetics and Molecular Biology, 3 (1), 17. doi:10.2202/1544-6115.1067
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Van Steen, K., & Molenberghs, G. (2004). Multicollinearity. In S.-C. Chow (Ed.), Encyclopedia of Biopharmaceutical Statistics.

Efficace, F., Biganzoli, L., Piccart, M., Coens, C., Van Steen, K., Cufer, T., Coleman, R. E., Calvert, H. A., Gamucci, T., Twelves, C., Fargeot, P., Bottomley, A., & Eortc-Bcg-Idbbc-Nddg. (2004). Baseline health-related quality-of-life data as prognostic factors in a phase III multicentre study of women with metastatic breast cancer. European Journal of Cancer, 40 (7), 1021-1030. doi:10.1016/j.ejca.2004.01.014
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Joossens, S., Daperno, M., Shums, Z., Van Steen, K., Goeken, J. A., Trapani, C., Norman, G. L., Godefridis, G., Claessens, G., Pera, A., Pierik, M., Vermeire, S., Rutgeerts, P., & Bossuyt, X. (2004). Interassay and interobserver variability in the detection of anti-neutrophil cytoplasmic antibodies in patients with ulcerative colitis. Clinical Chemistry, 50 (8), 1422-5. doi:10.1373/clinchem.2004.032318
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Murphy, A., Van Steen, K., & Lange, C. (2004). On missing phenotype data in multivariate family based association tests: FBAT-GEE-IMP and imputation strategies based on the EM-algorithm, the DA-algorithm and the conditional mean model. Far East Journal of Theoretical Statistics, 13 (2), 175-188.
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Bottomley, A., Thomas, R., Van Steen, K., Flechtner, H., & de Graeff, A. (2003). Guidelines for the use of epoetin: have quality-of-life benefits been proven? Journal of Clinical Oncology, 21 (11), 2223; author reply 2224-5. doi:10.1200/JCO.2003.99.208
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Joossens, S., Van Steen, K., Vermeire, S. V., Reinisch, W., Colombel, J. F., & Rutgeerts, P. (2003). The value of serologic markers in indeterminate colitis: A prospective follow-up study - Reply. Gastroenterology, 125 (3), 999-1000. doi:10.1016/S0016-5085(03)01154-6
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Jansen, I., Molenberghs, G., Aerts, M., Thijs, H., & Van Steen, K. (2003). A local influence approach applied to binary data from a psychiatric study. Biometrics, 59 (2), 410-9. doi:10.1111/1541-0420.00048
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Vermeire, S., Noman, M., Van Assche, G., Baert, F., Van Steen, K., Esters, N., Joossens, S., Bossuyt, X., & Rutgeerts, P. (2003). Autoimmunity associated with anti-tumor necrosis factor alpha treatment in Crohn's disease: A prospective cohort study. Gastroenterology, 125 (1), 32-39. doi:10.1016/S0016-5085(03)00701-7
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Vermeire, S., Esters, N., Pierik, M., Claessens, G., Joossens, S., Vlietinck, R., Van Steen, K., & Rutgeerts, P. (2003). Transmission of CARD15 (NOD2) variants in families with Crohns disease. Gastroenterology, 124 (4 (Suppl I)), 368.
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Van Steen, K., & Molenberghs, G. (2003). Multivariate and multidimensional analysis. In Wilson, Biometrics. Oxford, United Kingdom: Eolss.

Bottomley, A., Thomas, R., Van Steen, K., Flechtner, H., & Djulbegovic, B. (2002). Erythropoietin improves quality of life--a response. The Lancet Oncology, 3 (9), 527. doi:10.1016/S1470-2045(02)00844-6
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Van Steen, K., Molenberghs, G., & Tahri, N. (2002). The multivariate Dale model and genetic associations. American Journal of Human Genetics, 71, 577.
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Van Steen, K., Curran, D., Kramer, J., Molenberghs, G., Van Vreckem, A., Bottomley, A., & Sylvester, R. (2002). Multicollinearity in prognostic factor analyses using the EORTC QLQ-C30: identification and impact on model selection. Statistics in Medicine, 21 (24), 3865-3884. doi:10.1002/sim.1358
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Joossens, S., Van Steen, K., Vermeire, S. V., Reinisch, W., Colombel, J. F., & Rutgeerts, P. (2002). The value of serologic markers in indeterminate colitis: A prospective follow-up study. Gastroenterology, 122 (5), 1242-1247. doi:10.1053/gast.2002.32980
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Jansen, I., Van Steen, K., Molenberghs, G., De Wit, M., & Peeters, M. (2002). Using word frequencies for testing equivalence between two DNA sequences. Genetic Epidemiology, 23, 287.
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Bottomley, A., Thomas, R., Van Steen, K., Flechtner, H., & Djulbegovic, B. (2002). Human recombinant erythropoietin and quality of life: a wonder drug or something to wonder about? The Lancet Oncology, 3 (3), 145-53. doi:10.1016/S1470-2045(02)00677-0
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Van Steen, K., Molenberghs, G., & Tahri, N. (2002). Merits of the multivariate Dale model in genetic association studies. Genetic Epidemiology, 23, 309.
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Van Steen, K., Tahri, N., & Molenberghs, G. (2001). Introduction of the multivariate Dale model in genetic association studies. American Journal of Human Genetics, 69 (4), 1289.
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Thijs, H., Van Steen, K., Molenberghs, G., De Wit, M., & Peeters, M. (2001). An equivalence test for comparing DNA sequences. American Journal of Human Genetics, 69 (4), 1576.
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Van Steen, K., Curran, D., & Molenberghs, G. (2001). Sensitivity analysis of longitudinal binary quality of life data with drop-out: an example using the EORTC QLQ-C30. Statistics in Medicine, 20 (24), 3901-20. doi:10.1002/sim.1081
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Jansen, I., Molenberghs, G., Aerts, M., Thijs, H., & Van Steen, K. (2001). Analysis of binary data from a psychiatric study: a local influence approach. In Klein & Korsholm, Statistical Modelling. Proceedings of the 16th International Workshop on Statistical Modelling. New Trends in Statistical Modelling.
Peer reviewed

Van Steen, K., Molenberghs, G., Verbeke, G., & Thijs, H. (2001). A Local Influence Approach to Sensitivity Analysis of Incomplete Longitudinal Ordinal Data. Statistical Modelling, 1, 125-142. doi:10.1177/1471082X0100100203
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Van Maldeghem, H., & Van Steen, K. (1999). Characterizations by automorphism groups of some rank 3 buildings - IV: Hyperbolic p-adic Moufang buildings of rank 3. Geometriae Dedicata, 75 (2), 115-122. doi:10.1023/A:1005001130872
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Van Steen, K. (1999). Characterizations by automorphism groups of some rank 3 buildings, III. Moufang-like conditions. Geometriae Dedicata, 74 (3), 225-240. doi:10.1023/A:1005005214943
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Van Maldeghem, H., & Van Steen, K. (1999). Characterizations by automorphism groups of some rank 3 buildings - II: A half strongly-transitive locally finite triangle building is a Bruhat-Tits building. Geometriae Dedicata, 74 (2), 113-133. doi:10.1023/A:1005057231781
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Van Maldeghem, H., & Van Steen, K. (1998). Characterizations by automorphism groups of some rank 3 buildings - I. Some properties of half strongly-transitive triangle buildings. Geometriae Dedicata, 73 (2), 119-142. doi:10.1023/a:1005009315851
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Van Maldeghem, H., & Van Steen, K. (1997). Moufang affine buildings have Moufang spherical buildings at infinity. Glasgow Mathematical Journal, 39 (Part 3), 237-241. doi:10.1017/S001708950003216X
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