Profil

Fievez Laurence

GIGA I3 - Cellular and Molecular Immunology

Département des sciences fonctionnelles (DSF) > Biochimie et biologie moléculaire

See author's contact details
Main Referenced Co-authors
Bureau, Fabrice  (93)
Lekeux, Pierre  (52)
Desmet, Christophe  (35)
Gustin, Pascal  (29)
Kirschvink, Nathalie (23)
Main Referenced Keywords
Lung (11); Inflammation (10); Macrophages (7); Animals (6); lung (6);
Main Referenced Unit & Research Centers
GIGA-I3 - Giga-Infection, Immunity and Inflammation - ULiège (2)
Main Referenced Disciplines
Veterinary medicine & animal health (86)
Biochemistry, biophysics & molecular biology (36)
Anatomy (cytology, histology, embryology...) & physiology (12)
Immunology & infectious disease (8)
Life sciences: Multidisciplinary, general & others (4)

Publications (total 119)

The most downloaded
1890 downloads
Zhang, W., Fievez, L., Zhang, F., Cheu, E., Antoine, N., Delguste, C., Zhang, Y., Rong, W., Bureau, F., Advenier, C., & Gustin, P. (November 2010). Effects of formoterol and ipratropium bromide on repeated cadmium inhalation -induced pulmonary inflammation and emphysema in rats. European Journal of Pharmacology, 25 (647), 178-187. doi:10.1016/j.ejphar.2010.08.028 https://hdl.handle.net/2268/79150

The most cited

197 citations (OpenAlex)

Sabatel, C.* , Radermecker, C.* , Fievez, L.* , Paulissen, G., Chakarov, S., Fernandes, C., Olivier, S., Toussaint, M., Pirottin, D., Xiao, X., Quatresooz, P., Sirard, J.-C., Cataldo, D., Gillet, L., Bouabe, H., Desmet, C., Ginhoux, F., Marichal, T.* , & Bureau, F.*. (2017). Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages. Immunity, 46 (3), 457-473. doi:10.1016/j.immuni.2017.02.016 https://hdl.handle.net/2268/208629

Rizzoli, E., Fastrès, A., Fievez, L., Roels, E., Marichal, T., & Clercx, C. (2024). Unveiling the Tumour Microenvironment in Canine Pulmonary Adenocarcinoma Through Single-Cell RNA Sequencing. Journal of Veterinary Internal Medicine.
Peer Reviewed verified by ORBi

Legrand, C., Vanneste, D., Hego, A., Sabatel, C., Mollers, K., Schyns, J., Maréchal, P., Abinet, J., Tytgat, A., Liégeois, M., Polese, B., Meunier, M., Radermecker, C., Fievez, L., Bureau, F., & Marichal, T. (2024). Lung Interstitial Macrophages Can Present Soluble Antigens and Induce Foxp3+ Regulatory T Cells. American Journal of Respiratory Cell and Molecular Biology. doi:10.1165/rcmb.2023-0254OC
Peer Reviewed verified by ORBi

Thanasarnthungcharoen, C., Chanasit, S., Fievez, L., Kaewamatawong, T., Patniboon, P., Lin, P. J. C., Bureau, F., & Jacquet, A. (2024). Immunotherapeutic effects of specific and nonspecific mRNA-lipid nanoparticles in a mouse model of HDM-induced airway inflammation [letter to the editor]. Allergy. doi:10.1111/all.16049
Peer Reviewed verified by ORBi

Cesarini Latorre, C., de Meeûs d'Argenteuil, C., Delguste, C., Douny, C., Eppe, J., Fievez, L., Frisee, V., Gatez, C., Jauniaux, T., Ledeck, J., Levoz, M., Martinelle, L., Tosi, I., Votion, D., & Wouters, C. (Eds.). (2023). Proceedings of the 10th FARAH-Day. Liège, Belgium: Presses de la Faculté de Médecine Vétérinaire de l'ULiège.
Peer reviewed

Wambreuse, N., Caulier, G., Eeckhaut, I., Borrello, L., Bureau, F., Fievez, L., & Delroisse, J. (2023). Morpho-functional Characterisation of Cœlomocytes in the Aquacultivated Sea Cucumber Holothuria Scabra: From Cell Diversity to Transcriptomic Immune Response. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/315430. doi:10.2139/ssrn.4658658

Rizzoli, E., Fastrès, A., Fievez, L., Marichal, T., & Clercx, C. (2023). Generation of a comprehensive molecular cell atlas of the healthy canine lung. Journal of Veterinary Internal Medicine. doi:10.1111/jvim.16930
Peer Reviewed verified by ORBi

Vanneste, D., Bai, Q., Hasan, S., Peng, W., Pirottin, D., Schyns, J., Maréchal, P., Ruscitti, C., Meunier, M., Liu, Z., Legrand, C., Fievez, L., Ginhoux, F., Radermecker, C., Bureau, F., & Marichal, T. (March 2023). MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation. Nature Immunology, 24 (5), 827 - 840. doi:10.1038/s41590-023-01468-3
Peer Reviewed verified by ORBi

Belhaouane, I., Pochet, A., Chatagnon, J., Hoffmann, E., Queval, C. J., Deboosère, N., Boidin-Wichlacz, C., Majlessi, L., Sencio, V., Heumel, S., Vandeputte, A., Werkmeister, E., Fievez, L., Bureau, F., Rouillé, Y., Trottein, F.* , Chamaillard, M.* , Brodin, P.* , & Machelart, A.*. (March 2023). Tirap controls Mycobacterium tuberculosis phagosomal acidification. PLoS Pathogens, 19 (3), 1011192. doi:10.1371/journal.ppat.1011192
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Donneau, A.-F.* , Guillaume, M.* , BOURS, V., Dandoy, M., DARCIS, G., Desmecht, D., Diep, A. N., Fievez, L., Garigliany, M.-M., Gillain, N., Husson, E., Michel, F., MOUTSCHEN, M., Paridans, M., Pétré, B., Sabatel, C., Saegerman, C., Tytgat, A., Gillet, L.* , & Bureau, F.*. (2022). University population-based prospective cohort study of SARS-CoV- 2 infection and immunity (SARSSURV-ULiège): a study protocol. BMJ Open. doi:10.1136/bmjopen-2021-055721
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Liégeois, M., Bai, Q., Fievez, L., Pirottin, D., Legrand, C., Guiot, J., Schleich, F., Corhay, J.-L., Louis, R., Marichal, T., & Bureau, F. (2022). Airway Macrophages Encompass Transcriptionally and Functionally Distinct Subsets Altered by Smoking. American Journal of Respiratory Cell and Molecular Biology, 67 (2), 241 - 252. doi:10.1165/rcmb.2021-0563OC
Peer Reviewed verified by ORBi

Fastrès, A., Roels, E., Pirottin, D., Fievez, L., Tutunaru, A.-C., Bolen, G., Merveille, A.-C., Marichal, T., Desmet, C., Bureau, F., & Clercx, C. (2022). Osteopontin-expressing macrophages in dogs affected with canine idiopathic pulmonary fibrosis, a model for human idiopathic pulmonary fibrosis [Poster presentation]. 21st International Colloquium on Lung and Airway Fibrosis (ICLAF).

Cyriaque, V., Madsen, J. S., Fievez, L., Leroy, B., Hansen, L. H., Bureau, F., Sørensen, S. J., & Wattiez, R. (2021). Lead Drives Complex Dynamics of a Conjugative Plasmid in a Bacterial Community. Frontiers in Microbiology, 12, 655903. doi:10.3389/fmicb.2021.655903
Peer Reviewed verified by ORBi

Fastrès, A., Pirottin, D., Fievez, L., Tutunaru, A.-C., Bolen, G., Merveille, A.-C., Marichal, T., Desmet, C., Bureau, F., & Clercx, C. (15 December 2020). Identification of pro-fibrotic macrophage populations by single-cell transcriptomic analysis in West Highland white terriers affected with canine idiopathic pulmonary fibrosis. Frontiers in Immunology, 11, 611749. doi:10.3389/fimmu.2020.611749
Peer Reviewed verified by ORBi

Fastrès, A., Pirottin, D., Fievez, L., Tutunaru, A.-C., Bolen, G., Merveille, A.-C., Marichal, T., Desmet, C., Bureau, F., & Clercx, C. (20 November 2020). Identification of pro-fibrotic macrophages populations by single-cell transcriptomic analysis in West Highland white terriers affected with canine idiopathic pulmonary fibrosis [Paper presentation]. 7th FARAH DAY, Liège, Belgium.

Fastrès, A., Pirottin, D., Fievez, L., Marichal, T., Desmet, C., Bureau, F., & Clercx, C. (30 July 2020). Characterization of the bronchoalveolar lavage fluid by single cell gene expression analysis in healthy dogs: a promising technique. Frontiers in Immunology, 11, 1707. doi:10.3389/fimmu.2020.01707
Peer Reviewed verified by ORBi

Fastrès, A., Pirottin, D., Fievez, L., Marichal, T., Desmet, C., Bureau, F., & Clercx, C. (2020). Characterization of the bronchoalveolar lavage fluid by single cell gene expression analysis in healthy dogs: a promising technique. Journal of Veterinary Internal Medicine, 34 (6). doi:10.1111/jvim.15924

Bureau, F., Marichal, T., Desmet, C., Sabatel, C., Radermecker, C., Fievez, L., & olivier, S. (09 March 2017). Procédés de différenciation in vitro de monocytes en macrophages régulateurs.

Sabatel, C., Radermecker, C., Fievez, L., PAULISSEN, G., Chakarov, S., Fernandes, C., Olivier, S., Toussaint, M., Pirottin, D., Xiao, X., QUATRESOOZ, P., Sirard, J.-C., CATALDO, D., Gillet, L., Bouabe, H., Desmet, C., Ginhoux, F., Marichal, T., & Bureau, F. (01 February 2017). Bacterial CpG-DNA prevents asthma by expanding lung interstitial regulatory macrophages from local and splenic reservoir monocytes [Paper presentation]. GIGA DAY 2017, Liège, Belgium.

Brasseur, L., Hennebert, E., Fievez, L., Caulier, G., Bureau, F., Tafforeau, L., Flammang, P., Gerbaux, P., & Eeckhaut, I. (2017). The Roles of Spinochromes in Four Shallow Water Tropical Sea Urchins and Their Potential as Bioactive Pharmacological Agents. Marine Drugs, 15 (6). doi:10.3390/md15060179
Peer Reviewed verified by ORBi

Sabatel, C.* , Radermecker, C.* , Fievez, L.* , Paulissen, G., Chakarov, S., Fernandes, C., Olivier, S., Toussaint, M., Pirottin, D., Xiao, X., Quatresooz, P., Sirard, J.-C., Cataldo, D., Gillet, L., Bouabe, H., Desmet, C., Ginhoux, F., Marichal, T.* , & Bureau, F.*. (2017). Exposure to Bacterial CpG DNA Protects from Airway Allergic Inflammation by Expanding Regulatory Lung Interstitial Macrophages. Immunity, 46 (3), 457-473. doi:10.1016/j.immuni.2017.02.016
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Heinen, M.-P., Cambier, L., Fievez, L., & Mignon, B. (2017). Are Th17 Cells Playing a Role in Immunity to Dermatophytosis? Mycopathologia, 182 (1), 251-261. doi:10.1007/s11046-016-0093-5
Peer Reviewed verified by ORBi

Sabatel, C., Radermecker, C., Fievez, L., Paulissen, G., Chakarov, S., Toussaint, M., Desmet, C., Ginhoux, F., Marichal, T., & Bureau, F. (2016). CpG-DNA expand immunosuppressive interstitial macrophages from Ly6c+ local precursors. In Proceeding of Cell Symposia: 100 years of phagocytes.
Peer reviewed

Tosi, I., Pirottin, D., Fievez, L., Bureau, F., Denoix, J., Trachsel, D., Lekeux, P., & Art, T. (16 October 2015). Effect of a CpG-ODN on the innate immune system of the horse: an in-vivo trial [Poster presentation]. FARAH DAY, Liege, Belgium.

Sabatel, C., Radermecker, C., Fievez, L., Paulissen, G., Toussaint, M., Desmet, C., Marichal, T., Bureau, F., & Chakarov, S. (Other coll.). (08 September 2015). A lung-resident Ly6c+ monocyte proliferates to give rise to immunosuppressive lung macrophages [Poster presentation]. 4ème European Congress of Immunology, Vienne, Austria.

Sabatel, C., Radermecker, C., Fievez, L., Paulissen, G., Chakarov, S., Desmet, C., Ginhoux, F., Toussaint, M., Marichal, T., & Bureau, F. (2015). A lung-resident Ly6c+ monocyte proliferates to give rise to immunosuppressive lung macrophages [Poster presentation]. ERS International congress.

Sabatel, C., Radermecker, C., Chakarov, S., Fievez, L., PAULISSEN, G., Toussaint, M., Desmet, C., Ginhoux, F., Marichal, T., & Bureau, F. (2015). A lung-resident Ly6c+ monocyte proliferates to give rise to immunosuppressive lung macrophages. European Respiratory Journal. Supplement, 46 (59), 5098.
Peer Reviewed verified by ORBi

Pujol, J., Bouillenne, F., Farnir, F., Dufrasne, I., Mainil, J., Galleni, M., Lekeux, P., Bureau, F.* , & Fievez, L.*. (2015). Generation of a soluble recombinant trimeric form of bovine CD40L and its potential use as a vaccine adjuvant in cows. Veterinary Immunology and Immunopathology, 168 (1), 1-13. doi:10.1016/j.vetimm.2015.09.011
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Mayer, A., Debuisson, D., Denanglaire, S., Eddahri, F., Fievez, L., Hercor, M., Triffaux, E., Moser, M., Bureau, F., Leo, O., & Andris, F. (2014). Antigen presenting cell-derived IL-6 restricts Th2-cell differentiation. European Journal of Immunology, 44 (11), 3252-62. doi:10.1002/eji.201444646
Peer Reviewed verified by ORBi

Vanherberghen, M., Bureau, F., Peters, I. R., Day, M. J., Lynch, A., Fievez, L., Billen, F., Clercx, C., & Peeters, D. (15 August 2013). Cytokine and transcription factor expression by Aspergillus fumigatus-stimulated peripheral blood mononuclear cells in dogs with sino-nasal aspergillosis. Veterinary Immunology and Immunopathology, 154 (3-4), 111-20. doi:10.1016/j.vetimm.2013.05.009
Peer Reviewed verified by ORBi

Toussaint, M., Fievez, L., Drion, P., Cataldo, D., Bureau, F., Lekeux, P., & Desmet, C. (2013). Myeloid hypoxia-inducible factor 1alpha prevents airway allergy in mice through macrophage-mediated immunoregulation. Mucosal Immunology, 6 (3), 485-97. doi:10.1038/mi.2012.88
Peer Reviewed verified by ORBi

Toussaint, M., Fievez, L., Drion, P., Cataldo, D., Bureau, F., Lekeux, P., & Desmet, C. (2013). Myeloid Hif1alpha counteracts allergic airway sensitization in mice through macrophage-mediated immunoregulation. In Abstract book of Keystone Symposium "Myeloid Cells: Regulation and Inflammation".
Peer reviewed

Toussaint, M., Fievez, L., Drion, P., Cataldo, D., Bureau, F., Lekeux, P., & Desmet, C. (2012). Myeloid Hypoxia‐inducible factor 1α prevents airway allergy in mice through macrophage‐mediated immunoregulation. In Proceedings Giga Day 2012.
Peer reviewed

Toussaint, M., Fievez, L., Desmet, C., Pirottin, D., Farnir, F., Bureau, F., & Lekeux, P. (2012). Increased hypoxia-inducible factor 1alpha expression in lung cells of horses with recurrent airway obstruction. BMC Veterinary Research, 8 (1), 64. doi:10.1186/1746-6148-8-64
Peer Reviewed verified by ORBi

Wallemacq, H., Bedoret, D., Pujol, J., Desmet, C., Drion, P., Farnir, F., Mainil, J., Lekeux, P., Bureau, F., & Fievez, L. (2012). CD40 triggering induces strong cytotoxic T lymphocyte responses to heat-killed Staphylococcus aureus immunization in mice: a new vaccine strategy for staphylococcal mastitis. Vaccine, 30 (12), 2116-2124. doi:10.1016/j.vaccine.2012.01.039
Peer Reviewed verified by ORBi

Fernandes, C. A., Fievez, L., Neyrinck, A. M., Delzenne, N. M., Bureau, F., & Vanbever, R. (2012). Sirtuin inhibition attenuates the production of inflammatory cytokines in lipopolysaccharide-stimulated macrophages. Biochemical and Biophysical Research Communications, 420 (4), 857-861. doi:10.1016/j.bbrc.2012.03.088
Peer reviewed

Toussaint, M., Fievez, L., Lekeux, P., Bureau, F., & Desmet, C. (2011). Myeloid HIF-1alpha prevents airway allergy in mice by promoting macrophage-mediated immunosuppression. In Proceedings of the 1st Scientific Meeting of the Faculty of Veterinary Medicine (pp. 3). Liège, Belgium: Presses de la Faculté de Médecine Vétérinaire de l'Université de Liège.
Peer reviewed

Legutko, A.* , Marichal, T.* , Fievez, L., Bedoret, D., Mayer, A., de Vries, H., Klotz, L., Drion, P., Heirman, C., CATALDO, D., LOUIS, R., Thielemans, K., Andris, F., Leo, O., Lekeux, P., Desmet, C.* , & Bureau, F.*. (2011). Sirtuin 1 Promotes Th2 Responses and Airway Allergy by Repressing Peroxisome Proliferator-Activated Receptor-γ Activity in Dendritic Cells. Journal of Immunology, 187 (9), 4517-4529. doi:10.4049/jimmunol.1101493
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Fernandes, C. A.* , Fievez, L.* , Ucakar, B., Neyrinck, A. M., Fillee, C., Huaux, F., Delzenne, N. M., Bureau, F., & Vanbever, R. (2011). Nicotinamide enhances apoptosis of G(M)-CSF-treated neutrophils and attenuates endotoxin-induced airway inflammation in mice. American Journal of Physiology - Lung Cellular and Molecular Physiology, 300 (3), 354-61. doi:10.1152/ajplung.00198.2010
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Zhang, W., Fievez, L., Zhang, F., Cheu, E., Antoine, N., Delguste, C., Zhang, Y., Rong, W., Bureau, F., Advenier, C., & Gustin, P. (November 2010). Effects of formoterol and ipratropium bromide on repeated cadmium inhalation -induced pulmonary inflammation and emphysema in rats. European Journal of Pharmacology, 25 (647), 178-187. doi:10.1016/j.ejphar.2010.08.028
Peer Reviewed verified by ORBi

Ramery, E., Fievez, L., Fraipont, A., Bureau, F., & Lekeux, P. (2010). Characterization of pentraxin 3 in the horse and its expression in airways. Veterinary Research, 41 (2), 18. doi:10.1051/vetres/2009066
Peer Reviewed verified by ORBi

Zhang, W. H., Fievez, L., Cheu, E., Rong, W. F., Zhang, F., Bureau, F., Advenier, C., & Gustin, P. (2010). Effects of formoterol,ipratropium and their combination on repeated cadmium inhalation-induced lung inflammation and airspace enlargement. Fundamental and Clinical Pharmacology, 10, 24.
Peer Reviewed verified by ORBi

Zhang, W. H., Fievez, L., Cheu, E., Rong, W. F., Zhang, Y., Bureau, F., Advenier, C., & Gustin, P. (2010). Effects of ipratropium bromide on repeated cadmium inhalation-induced lune inflammation and airspace enlargement in rats. Fundamental and Clinical Pharmacology, 10, 24.
Peer Reviewed verified by ORBi

Zhang, W., Fievez, L., Cheu, E., Bureau, F., Rong, W., Zhang, F., Zhang, Y., Advenier, C., & Gustin, P. (2010). Anti-inflammatory effects of formoterol and ipratropium bromide against acute cadmium-induced pulmonary inflammation in rats. European Journal of Pharmacology, 628 (1-3), 171-178. doi:10.1016/j.ejphar.2009.11.015
Peer Reviewed verified by ORBi

Vanherberghen, M., Bureau, F., Peters, I. R., Fievez, L., Billen, F., Clercx, C., & Peeters, D. (2010). Cytokine expression by Aspergillus fumigatus stimulated peripheral blood mononuclear cells from dogs with sino-nasal aspergillosis. In Proceedings of the 20th Annual Congress of the ECVIM-CA (pp. 242).
Peer reviewed

Fernandez, C. A., Fievez, L., Bureau, F., & Vanbever, R. (2010). Sirtuin inhibition modulates endotoxin-induced lung inflammation. In Shortbook: Annual Congress of the European Respiratory Society (ERS).
Peer reviewed

Fievez, L., Kirschvink, N., Zhang, W. H., Lagente, V., Lekeux, P., Bureau, F., & Gustin, P. (2009). Effects of betamethasone on inflammation and emphysema induced by cadmium nebulisation in rats. European Journal of Pharmacology, 606 (1-3), 210-214. doi:10.1016/j.ejphar.2009.01.020
Peer Reviewed verified by ORBi

Legutko, A., Marichal, T., Fievez, L., Mayer, A., Andris, F., Léo, O., Lekeux, P., & Bureau, F. (2009). Essential role of sirtuins in the pathogenesis of allergic airway inflammation. In Short book of the Annual Congress of the European Respiratory Society (ERS), Vienne.
Peer reviewed

Fernandes, C. A., Fievez, L., Ucakar, B., Neyrinck, A. M., Fillee, C., Huaux, F., Delzenne, N. M., Bureau, F., & Vanbever, R. (2009). Local administration of nicotinamide enhances neutrophil apoptosis and decreases mice endotoxin-induced airway inflammation. In Société Belge de Sciences Pharmaceutiques.
Peer reviewed

Zhang, Y., Fievez, L., Cheu, E., Rong, W. F., Zhang, F., Bureau, F., Advenier, C., & Gustin, P. (2008). Anti-inflammatory effects of ipratropium bromide in rats with cadmium-induced acute pulmonary inflammation. Fundamental and Clinical Pharmacology, 22 (1), 7.
Peer Reviewed verified by ORBi

Henry, E., Desmet, C., Garze, V., Fievez, L., Bedoret, D., Heirman, C., Faisca, P., Jaspar, F., Gosset, P., Jacquet, A., Desmecht, D., Thielemans, K., Lekeux, P., Moser, M., & Bureau, F. (2008). Dendritic cells genetically engineered to express IL-10 induce long-lasting antigen-specific tolerance in experimental asthma. Journal of Immunology, 181 (10), 7230-7242. doi:10.4049/jimmunol.181.10.7230
Peer Reviewed verified by ORBi

Zhang, W., Fievez, L., Cheu, E., Rong, W. F., Zhang, F., Bureau, F., Advenier, C., & Gustin, P. (2008). Anti-inflammatory effects of ipratropium bromide in rats with cadmium-induced acute pulmonary inflammation. In Proceedings of the 12th Annual Meeting of the French Society of Pharmacology and Therapeutics.
Peer reviewed

Zhang, W., Fievez, L., Cheu, E., Steuve, J., Dortu, P., Zhang, Y., Rong, W. F., Bureau, F., Advenier, C., & Gustin, P. (2008). Role of beta 2-receptors in the anti-inflammatory effects of formoterol in rats with cadmium-induced acute pulmonary inflammation. Fundamental and Clinical Pharmacology, 227, 22.
Peer Reviewed verified by ORBi

Cheu, E., Steuve, J., Fievez, L., Zhang, W., Dortu, P., Bureau, F., & Gustin, P. (2008). Investigation of pulmonary expression of heat shock protein HSP70 in mice chronically exposed to cigarette smoke. Acta Physiologica, 192 (662), 19.
Peer Reviewed verified by ORBi

Beaufays, J., Adam, B., Menten, C., Fievez, L., Grosjean, A., Decrem, Y., Prevot, P.-P., Santini, S., Brasseur, R., Brossard, M., Vanhaeverbeek, M., Bureau, F., Heinen, E., Lins, L., Vanhamme, L., & Godfroid, E. (2008). Ir-LBP, an ixodes ricinus tick salivary LTB4-binding lipocalin, interferes with host neutrophil function. PLoS ONE, 3 (12), 3987. doi:10.1371/journal.pone.0003987
Peer Reviewed verified by ORBi

Steuve, J., Cheu, E., Fievez, L., Zhang, W., Dortu, P., Bureau, F., & Gustin, P. (2008). Influence of different exposure conditions to cigarette smoke on the pulmonary acute inflammatory response in mice. Acta Physiologica, 192 (suppl. 662), 18.
Peer Reviewed verified by ORBi

Fievez, L. (2007). Roles of the STAT5 transcription factor in neutrophil homeostasy and inflammation. Annales de Médecine Vétérinaire, 151 (Spécial), 73-76.
Peer Reviewed verified by ORBi

Cheu, E., Steuve, J., Fievez, L., Zhang, W., Dortu, P., Bureau, F., & Gustin, P. (2007). Investigation of pulmonary expression of heat shock protein HSP70 in mice chronically exposed to cigarette smoke. In Proceedings: Autumn Meeting of the Belgian Society of Fundamental and Clinical Physiology and Pharmacology.
Peer reviewed

Fievez, L., Desmet, C., Henry, E., Pajak, B., Hegenbarth, S., Garze, V., Bex, F., Jaspar, F., Boutet, P., Gillet, L., Vanderplasschen, A., Knolle, P. A., Leo, O., Moser, M., Lekeux, P., & Bureau, F. (2007). Stat5 Is an Ambivalent Regulator of Neutrophil Homeostasis. PLoS ONE, 2 (1), 727. doi:10.1371/journal.pone.0000727
Peer Reviewed verified by ORBi

Steuve, J., Cheu, E., Fievez, L., Zhang, W., Dortu, P., Bureau, F., & Gustin, P. (2007). Influence of different exposure conditions to cigarette smoke on the pulmonary acute inflammatory response in mice. In Proceedings: Autumn Meeting of the Belgian Society of Fundamental and Clinical Physiology and Pharmacology.
Peer reviewed

Henry, E., Desmet, C., Garzé, V., Fievez, L., Bedoret, D., Heirman, C., Faisca, P., Jaspar, F. J., Gosset, P., Jacquet, A. P. A., Desmecht, D., Lekeux, P., Moser, M., & Bureau, F. (2007). Dendritic cells genetically engineered to express IL-10 induce long-lasting antigen-specific tolerance in experimental asthma [Poster presentation]. 11ème BIOFORUM de Liège, Liège, Belgium.

Zhang, W., Zhang, F., Fievez, L., Cheu, E., Steuve, E., Dortu, P., Zhang, Y., Rong, W. F., Bureau, F., Adevenier, C., & Gustin, P. (2007). Role of beta 2-receptors in the anti-inflammatory effects of formoterol in rats with cadmium-induced acute pulmonary inflammation. In Proceedings: Autumn Meeting of the Belgian Society of Fundamental and Clinical Physiology and Pharmacology.
Peer reviewed

Zhang, W., Fievez, L., Cheu, E., Zhang, F., Rong, W. F., Bureau, F., Advenier, C., & Gustin, P. (2007). Effects of formoterol on repeated cadmium inhalation-induced lung inflammation and emphysema in rats. In Proceedings : Congrès de physiologie, de pharmacologie et de thérapeutique P2T.
Peer reviewed

Fievez, L., Desmet, C., Henry, E., Pajak, B., Hegenbarth, S., Garzé, V., Bex, F., Jaspar, F., Boutet, P., Gillet, L., Vanderplasschen, A., Knolle, P. A., Leo, O., Moser, M., Lekeux, P., & Bureau, F. (2007). STAT5 is an Ambivalent Regulator of Neutrophil Homeostasis [Poster presentation]. 11ème BIOFORUM de Liège, Liège, Belgium.

Zhang, W. H., Fievez, L., Cheu, E., Zhang, F., Rong, W. F., Bureau, F., Advenier, C., & Gustin, P. (2007). Anti-inflammatory effects of formoterol in rats after a single dose inhalation of nebulized cadmium. Fundamental and Clinical Pharmacology, 74, 21.
Peer Reviewed verified by ORBi

Fievez, L. (2006). Rôles du facteur de transcription STAT5 dans l’homéostasie des neutrophiles et l’inflammation [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/267993

Kirschvinck, N., Fievez, L., Provins, L., Marlin, D., & Gustin, P. (2006). Modulation of airway inflammation and pulmonary oxidative markers in cadmium-exposed rats by theophylline and compound UCB-101333-3. In Proceedings: 24th Symposium of the Veterinary Comparative Respiratory Society.
Peer reviewed

Fievez, L., Kirschvinck, N., Belleflamme, N., Lagente, V., & Gustin, P. (2006). Effects of the MMP inhibitor GM-6001 on emphysema development, infllammation and MMPs activity induced by cadmium in rats. Fundamental and Clinical Pharmacology, 20, 194.
Peer Reviewed verified by ORBi

Kirschvink, N., Martin, N., Fievez, L., Smith, N., Marlin, D., & Gustin, P. (2006). Airway inflammation in cadmium-exposed rats is associated with pulmonary oxidative stress and emphysema. Free Radical Research, 40 (3), 241-250. doi:10.1080/10715760500494657
Peer Reviewed verified by ORBi

Fievez, L., Kirschvinck, N., Belleflamme, M., Lagente, V., & Gustin, P. (2006). Effects of MMP inhibition on emphysema development, Inflammation induced by cadmium in rats. In Proceedings of IUPHAR Congress, Pékin, Chine. IUPHAR Congress, Pékin, Chine en juillet 2006.
Peer reviewed

Fievez, L., Kirschvink, N., Belleflamme, M., Onclinx, C., & Gustin, P. (2005). Cadmium inhalation-induced emphysema is resistant to glucocorticoids. European Respiratory Journal.
Peer Reviewed verified by ORBi

Kirschvink, N., Vincke, G., Fievez, L., Onclinx, C., Wirth, D., Belleflamme, M., Louis, R., Cataldo, D., Peck, M. J., & Gustin, P. (2005). Repeated cadmium nebulizations induce pulmonary MMP-2 and MMP-9 production and emphysema in rats. Toxicology, 211 (1-2), 36-48. doi:10.1016/j.tox.2005.02.012
Peer Reviewed verified by ORBi

Fievez, L., Kirschvink, N., Provins, L., & Gustin, P. (2005). Effect of substance 101333-3 on emphysema and MMP activity in a model of cadmium-induced emphysema. European Respiratory Journal, 579s, 26.
Peer Reviewed verified by ORBi

Fievez, L., Seumois, G., Lekeux, P., & Bureau, F. (2005). L’apoptose du neutrophile. Annales de Médecine Vétérinaire, 149, 10-19.
Peer Reviewed verified by ORBi

Desmet, C., Gosset, P., Garzé, V., Pajak, B., Fievez, L., Lekeux, P., & Bureau, F. (2005). Selective inhibition of AP-1 activity in airway immune cells ameliorates experimental asthma. In Proceedings: The American Thoracic Society (pp. 737).
Peer reviewed

Desmet, C., Warzée, B., Gosset, P., Melotte, D., Rongvaux, A., Gillet, L., Fievez, L., Seumois, G., Vanderplasschen, A., Staels, B., Lekeux, P., & Bureau, F. (2005). Pro-inflammatory properties for thiazolidinediones. Biochemical Pharmacology, 69 (2), 255-265. doi:10.1016/j.bcp.2004.09.017
Peer Reviewed verified by ORBi

Fievez, L., Kirschvink, N., Onclinx, C., Belleflamme, M., Desmet, C., Peck, M., & Gustin, P. (2005). Protection by theophylline of inflammation and emphysema induced by repeated inhalation of cadmium chloride in rats. American Journal of Respiratory and Critical Care Medicine, 171, 93.
Peer Reviewed verified by ORBi

Kirschvink, N., Fievez, L., Desmet, C., Peck, M., Smith, N., Marlin, D., & Gustin, P. (2005). Theophylline increases glutathione in BAL of cadmium-exposed rats. In Proceedings of the American Thoracic Society, San Diego, California (pp. 750).
Peer reviewed

Kirschvink, N., Fievez, L., Marlin, D., Smith, N., Provins, L., & Gustin, P. (2005). Substance 101333-3 reduces pulmonary oxidative stress in cadmium-exposed rats. European Respiratory Journal, 104s, 26.
Peer Reviewed verified by ORBi

Fievez, L., Desmet, C., Seumois, G., Vanderplasschen, A., Lekeux, P., & Bureau, F. (2005). STAT5 promotes granulocyte survival during inflammation. American Journal of Respiratory and Critical Care Medicine, 171, 325.
Peer Reviewed verified by ORBi

Kirschvink, N., Leemans, J., Delvaux, F., Clercx, C., Fievez, L., Desmet, C., & Gustin, P. (2005). Repeatability of allergen challenges in a feline model of asthma : effect on airway reactivity and airway inflammation. In Proceedings of the American Thoracic Society, San Diego, California (pp. 780).
Peer reviewed

Kirschvink, N., Fievez, L., Leemans, J., Delvaux, F., Clercx, C., Martin, D., & Gustin, P. (2004). Indices of oxidative stress in a feline model of asthma : 8-Iso-PGF2 in bronchoalveolar lavaeg and H2O2 in exhaled breath condensate. In European Respir Journal volume 24 - S680. European Respiratory Journal ed.
Peer reviewed

Fievez, L., Desmet, C., Pajak, B., Gillet, L., Vanderplasschen, A., Lekeux, P., & Bureau, F. (2004). STAT5 promotes granulocyte survival during inflammation. Pflügers Archiv: European Journal of Physiology, 447, 8-24.
Peer Reviewed verified by ORBi

Fievez, L., Desmet, C., Seumois, G., Pajak, B., Gillet, L., Vanderplasschen, A., Lekeux, P., & Bureau, F. (2004). STAT5 promotes granulocyte survival during lung inflammation. In Proceedings: 22nd Symposium of the Veterinary and Comparative Respiratory Society (pp. 69). Veterinary and Comparative Respiratory Society.
Peer reviewed

Vincke G., Kirschvinck, N., Fievez, L., Desmet, C., & Gustin, P. (2004). Repeated cadmium nebulization induces MMP-2 and MMP-9 activation in bronchoalveolar lavage fluid of rats. In Repeated cadmium nebulization induces MMP-2 and MMP-9 activation in bronchoalveolar lavage fluid of rats. Veterinary and Comparative respiratory Society.
Peer reviewed

Vincke G., Kirschvink, N., Fievez, L., Bureau, F., Peck, M., & Gustin, P. (2004). Investigation of the frequency dependence of total pulmonary resistance and Penh during carbachol challenge in rats. European Respiratory Journal. Supplement, 24, 711.
Peer Reviewed verified by ORBi

Fievez, L., Desmet, C., Pajak, B., Gillet, L., Vanderplasschen, A., Lekeux, P., & Bureau, F. (2003). STAT5 promotes granulocyte survival during inflammation [Poster presentation]. Autumn Meeting of the Belgian Society of Fundamental and Clinical Physiology and Pharmacology, Liège, Belgium.

Eeckhaut, I., Fievez, L., & Muller, M. C. (2003). Larval development of Myzostoma cirriferum (Myzostomida). Journal of Morphology, 258, 269-283. doi:10.1002/jmor.10160
Peer Reviewed verified by ORBi

Kirschvink, N., Fievez, L., Bougnet, V., Art, T., Degand, G., Smith, N., Marlin, D., Roberts, C., Harris, P., & Lekeux, P. (2002). Effect of nutritional antioxidant supplementation on systemic and pulmonary antioxidant status, airway inflammation and lung function in heaves-affected horses. Equine Veterinary Journal, 34, 705-712. doi:10.2746/042516402776250298
Peer Reviewed verified by ORBi

Kirschvink, N., Smith, N., Fievez, L., Bougnet, V., Art, T., Degand, G., Marlin, D., Roberts, C., Genicot, B., Lindsey, P., & Lekeux, P. (2002). Effect of chronic airway inflammation and exercise on pulmonary and systemic antioxidant status of healthy and heaves-affected horses. Equine Veterinary Journal, 34 (6), 563-571. doi:10.2746/042516402776180223
Peer Reviewed verified by ORBi

Kirschvink, N., Fievez, L., Bureau, F., Degand, G., Maghuin-Rogister, G., Smith, N., Art, T., & Lekeux, P. (2002). Adaptation to multiday ozone exposure is associated with a sustained increase of bronchoalveolar uric acid. Free Radical Research, 36 (1), 23-32. doi:10.1080/10715760210169
Peer Reviewed verified by ORBi

Fievez, L., Kirschvink, N., Dogne, S., Jaspar, F., Merville, M.-P., Bours, V., Lekeux, P., & Bureau, F. (01 September 2001). Impaired Accumulation of Granulocytes in the Lung During Ozone Adaptation. Free Radical Biology and Medicine, 31 (5), 633-641. doi:10.1016/S0891-5849(01)00621-9
Peer Reviewed verified by ORBi

Sandersen, C., Bureau, F., Turlej, R., Fievez, L., Dogne, S., Kirschvink, N., & Lekeux, P. (10 August 2001). P65 Homodimer Activity in Distal Airway Cells Determines Lung Dysfunction in Equine Heaves. Veterinary Immunology and Immunopathology, 80 (3-4), 315-26. doi:10.1016/S0165-2427(01)00329-4
Peer Reviewed verified by ORBi

Turlej, R., Sandersen, C., Fievez, L., Dogné, S., Kirschvink, N., Lekeux, P., & Bureau, F. (2001). Enhanced survival of lung granulocytes in an animal model of asthma : evidence for a role of GM-CSF-activated STAT5 signaling pathway. In Proceedings: International Conference of the American Thoracic Society.
Peer reviewed

Fievez, L., Kirschvink, N., Lekeux, P., & Bureau, F. (2001). Adaptation to multiday ozone exposure is associated with a failure in granulocytes apoptosis delay. In Proceedings: International Conference of the American Thoracic Society.
Peer reviewed

Kirschvink, N., Fievez, L., Dogné, S., Bureau, F., Art, T., & Lekeux, P. (2001). Comparison of inulin to urea as dilutional marker of bronchoalveolar lavage in an animal model of asthma. In Proceedings: International Conference of the American Thoracic Society.
Peer reviewed

Turlej, R., Sandersen, C., Fievez, L., Dogné, S., Kirschvink, N., Lekeux, P., & Bureau, F. (2001). Enhanced survival of lung granulocytes in an animal model of asthma: evidence for a role of GM-CSF-activated STAT5 signaling pathway. In Proceedings: World Equine Airways Symposium.
Peer reviewed

Sandersen, C., Bureau, F., Turlej, R., Fievez, L., Dogné, S., Kirschvink, N., & Lekeux, P. (2001). p65 homodimer activity in BAL cells is correlated to lung dysfunction in equine heaves. In Proceedings: 2001 World Equine Airways Symposium.
Peer reviewed

Turlej, R. K.* , Fievez, L.* , Sandersen, C., Dogne, S., Kirschvink, N., Lekeux, P., & Bureau, F. (2001). Enhanced survival of lung granulocytes in an animal model of asthma: evidence for a role of GM-CSF activated STAT5 signalling pathway. Thorax, 56 (9), 696-702. doi:10.1136/thorax.56.9.696
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Kirschvink, N., Smith, N., Fievez, L., Art, T., Marlin, D., Roberts, C., & Lekeux, P. (2001). Effect of chronic airway inflammation and exercise on pulmonary and systemic antioxidant status of healthy and heaves-affected horses. In Proceeding of World Equine Airways Symposium (pp. 55). World Equine Airways Symposium.
Peer reviewed

Sandersen, C., Bureau, F., Turlej, R., Fievez, L., Dogné, S., Kirschvink, N., & Lekeux, P. (2001). Increased NF-kB activity in broncho-alveolar lavage cells from an animal model of asthma. In Proceedings: International Conference of the American Thoracic Society.
Peer reviewed

Fievez, L., Kirschvink, N., Dogné, S., Jaspar, F., Merville, M. P., Bours, V., Lekeux, P., & Bureau, F. (2001). Ozone adaptation in calves is associated with impaired accumulation of granulocytes in the lung. In Proceedings: Comparative Respiratory Society Meeting (pp. 62). Comparative Respiratory Society Meeting.
Peer reviewed

Kirschvink, N., Jacqmot, O., Fievez, L., Bureau, F., Degand, G., Art, T., Pincemail, J., & Lekeux, P. (2001). Antioxidant vitamin cocktail does not improve calves'lung function and airway inflammation in ozone-induced pulmonary disease. Pflügers Archiv: European Journal of Physiology, 442, 42.
Peer Reviewed verified by ORBi

Kirschvink, N., Fievez, L., Jacqmot, O., Bureau, F., Pincemail, J., Art, T., & Lekeux, P. (2001). Effect of preventive antioxidant supplementation on lung function, airway inflammation and pulmonary 8-epi-PGF2 of calves exposed to ozone. In Proceedings: Réunion de la Société Belge de Physiologie et de Pharmacologie Fondamentales et Cliniques.
Peer reviewed

Desmet, C., Fievez, L., LOUIS, R., Lekeux, P., & Bureau, F. (2001). NF-kappaB-dependent cytokine production is abolished by cyclopentenone prostaglandins in lung epithelial cells. European Respiratory Journal. Supplement, 18, 354.
Peer Reviewed verified by ORBi

Bureau, F., Fievez, L., Kirschvink, N., Sandersen, C., Turlej, R., & Lekeux, P. (2001). Mécanismes de la persistance de l’inflammation chez les chevaux poussifs en rémission. In Proceedings: 27ème Journée de la Recherche Equine.
Peer reviewed

Desmet, C., Fievez, L., Lekeux, P., & Bureau, F. (2001). Cyclopenone prostaglandins inhibit NF-κB activity and inflammatory gene expression in lung epithelial cells. In World Equine Airways Symposium (pp. 61). World Equine Airways Symposium editor.
Peer reviewed

Kirschvink N., Fievez, L., Bureau, F., Degand, G., Maghuin-Rogister, G., Smith, N., Art, T., & Lekeux, P. (2001). Adaptation to multiday ozone exposure is associated with a sustained increase of bronchoalveolar uric acid. In Proceeding of World Equine Airways Symposium (pp. 56). World Equine Airways Symposium.
Peer reviewed

Kirschvink N., Fievez, L., Bureau, F., Jacqmot, O., Art, T., & Lekeux, P. (2001). Ozone-induced pulmonary dysfunction and airway inflammation are not improved by antioxidant vitamin cocktail in calves. In Proceeding of World Equine Airways Symposium (pp. 57-58). World Equine Airways Symposium.
Peer reviewed

Kirschvink, N., Fievez, L., Dogne, S., Bureau, F., Art, T., & Lekeux, P. (2001). Comparison of inulin with urea as dilutional markers of bronchoalveolar lavage in healthy and heaves-affected horses. Veterinary Research, 32 (2), 145-154. doi:10.1051/vetres:2001117
Peer Reviewed verified by ORBi

Bureau, F., Delhalle, S., Bonizzi, G., Fievez, L., Dogne, S., Kirschvink, N., Vanderplasschen, A., Merville, M.-P., Bours, V., & Lekeux, P. (15 November 2000). Mechanisms of Persistent Nf-Kappa B Activity in the Bronchi of an Animal Model of Asthma. Journal of Immunology, 165 (10), 5822-5830. doi:10.4049/jimmunol.165.10.5822
Peer Reviewed verified by ORBi

Turlej, R. K., Sandersen, C., Fievez, L., Dogné, S., Kirschvink, N., Bureau, F., & Lekeux, P. (2000). Granulocyte macrophage-colony stimulating factor delay granulocytic apoptosis in heaves-affected horses. Pflügers Archiv: European Journal of Physiology, 440, 219.
Peer Reviewed verified by ORBi

Sandersen, C., Turlej, R. K., Fievez, L., Dogné, S., Kirschvink, N., Bureau, F., & Lekeux, P. (2000). Nuclear factor kappaB activity and characterization in lung cells from heaves-affected horses. Pflügers Archiv: European Journal of Physiology, 440, 217.
Peer Reviewed verified by ORBi

Bureau, F., Delhalle, S., Bonizzi, G., Fievez, L., Kirschvink, N., Dogné, S., Merville, M.-P., Bours, V., & Lekeux, P. (2000). An autocrine mechanism maintains persistent nuclear factor-kB activation in the bronchi of an animal model of asthma. In Proceedings: International Conference of the American Thoracic Society.
Peer reviewed

Bureau, F., Fievez, L., Detilleux, J., Uystepruyst, C., Coghe, J., Leroy, P., & Lekeux, P. (1999). Relationships between spirometric performances and occurrence and severity of respiratory disease in Belgian Blue calves. In Proceedings: 17th Symposium of the Comparative Respiratory Society.
Peer reviewed

Fievez, L. (1999). Voie inhibitrice du facteur nucléaire kB dans les cellules épithéliales bronchiques du cheval sain et atteint d’obstruction récurrente des voies respiratoires [Specialised master, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/267998

Bureau, F., Fievez, L., Michaux, C., Uystepruyst, C., Leroy, P., & Lekeux, P. (1999). Genetic parameters estimation for spirometric performances in Belgian Blue calves. In Proceedings: 17th Symposium of the Comparative Respiratory Society.
Peer reviewed

Bureau, F., Fievez, L., Kirschvink, N., & Lekeux, P. (1999). Transcription factor, nuclear factor-kB, activity in bronchial epithelial cells of RAO horses. In Proceedings: 17th Symposium of the Comparative Respiratory Society.
Peer reviewed

Eeckaut, I., Fievez, L., & Jangoux, M. (1998). Fine structure of the larvae of the Myzostoma cirriferum (Myzostomida) [Poster presentation]. The sixth International Polychaete Conference, Curitiba, Brazil.

Fievez, L. (1997). Etude sur le développement embryonnaire et larvaire de Myzostoma cirriferum (Myzostomida), symbiote obligatoire de la comatule Antedon bifida (Echinodermata) [Specialised master, Université de Mons-Hainaut]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/267999

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