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Thonon David

Main Referenced Co-authors
Luxen, André  (24)
Lemaire, Christian  (15)
Kaisin, Geoffroy  (13)
Desreux, Jean-François  (11)
Paris, Jérôme  (11)
Main Referenced Keywords
click chemistry (3); positron emission tomography (3); agent de contraste (1); alpha-synuclein (1); azide (1);
Main Referenced Unit & Research Centers
GIGA CRC (Cyclotron Research Center) In vivo Imaging-Aging & Memory - ULiège [BE] (9)
Center for Education and Research on Macromolecules (CERM) (1)
Main Referenced Disciplines
Chemistry (35)
Radiology, nuclear medicine & imaging (2)
Materials science & engineering (1)

Publications (total 37)

The most downloaded
233 downloads
Thonon, D., Flagothier, J., Paris, J., Mercier, F., Kaisin, G., Kech, C., Lemaire, C., Plenevaux, A., & Luxen, A. (August 2008). 18F LABELING OF BIOMOLECULES USING CLICK CHEMISTRY FOR PET APPLICATIONS : SYNTHETIC DEVELOPMENTS. Drugs of the Future, 33 (A), 235. https://hdl.handle.net/2268/71266

The most cited

72 citations (Scopus®)

Thonon, D., Paris, J., Kech, C., Lemaire, C., & Luxen, A. (26 March 2009). New Strategy for the Preparation of Clickable Peptides and Labeling with 1-(Azidomethyl)-4-[18F]-fluorobenzene for PET. Bioconjugate Chemistry, 20 (4), 817-823. doi:10.1021/bc800544p https://hdl.handle.net/2268/67849

Korat, Š., Bidesi, N. S. R., Bonanno, F., Di Nanni, A., Hoang Nguyen Nhat Anh, Herfert, K., Maurer, A., Battisti, U. M., Bowden, G. D., Thonon, D., Vugts, D., Windhorst, A. D., & Herth, M. M. (26 August 2021). Alpha-Synuclein PET Tracer Development-An Overview about Current Efforts. Pharmaceuticals, 14 (9), 847. doi:10.3390/ph14090847
Peer reviewed

Flagothier, J., Kaisin, G., Mercier, F., Thonon, D., Teller, N., Wouters, J., & Luxen, A. (August 2012). Synthesis of two new alkyne-bearing liners used for the preparation of siRNA for labeling by click chemistry with fluorine-18. Applied Radiation and Isotopes, 70 (8), 1549-1557.
Peer Reviewed verified by ORBi

Paris, J., Thonon, D., Kaisin, G., Goblet, D., Goukens, E., Lacroix, S., & Luxen, A. (01 September 2011). Automated synthesis of [18F] FBEM for labeling of thiol containing compounds [Poster presentation]. 19th International Symposium on Radiopharmaceutical Sciences (ISRS), Amsterdam, Netherlands. doi:10.1002/jlcr.1926

Kaisin, G., Paris, J., Flagothier, J., Thonon, D., & Luxen, A. (01 September 2011). Direct conversion of alcohol into azide : Drastically shortening the radiosynthesis of 4-azidomethyl-[18F]fluorobenzene [Poster presentation]. 19th International Symposium on Radiopharmaceutical Sciences (ISRS), Amsterdam, Netherlands.

Thonon, D., Goukens, E., Kaisin, G., Paris, J., Flagothier, J., & Luxen, A. (2011). Photoactivated 1,3-dipolar cycloaddition for the rapid preparation of 18F labelled radiotracers. Tetrahedron, 67, 5572-5576. doi:10.1016/j.tet.2011.05.122
Peer Reviewed verified by ORBi

collet, C., Lamandé-Langle, S., Balentova, E., Chrétien, F., Thonon, D., Aerts, J., Lemaire, C., Luxen, A., & Chapleur, Y. (2011). Synthesis and hydrolytic stability of novel 3-[18F]fluoroethoxybis(1-methylethyl)silyl]propanaminebased prosthetic groups [Poster presentation]. 19th International Symposium on Radiopharmaceutical Sciences.

Sriram, R., Lagerstedt, J., Petrlova, J., Samardzic, H., Kreutzer, U., Xie, H., Kaysen, G., Desreux, J.-F., Thonon, D., Jacques, V., Van Loan, M., Rutledge, J. C., Oda, M. N., Voss, J., & Jue, T. (2011). Imaging apolipoprotein AI in vivo. NMR in Biomedicine, 24 (7), 916-924. doi:10.1002/nbm.1650
Peer Reviewed verified by ORBi

Thonon, D., Goukens, E., Kaisin, G., Flagothier, J., paris, J., & Luxen, A. (2011). Photoclick chemistry: Applications to 18F radiotracers preparation. In Journal of Labelled Compounds and Radiopharmaceuticals. John Wiley & Sons Ltd.
Peer reviewed

Thonon, D., Goblet, D., Goukens, E., Kaisin, G., Paris, J., Aerts, J., Lignon, S., Franci, X., Hustinx, R., & Luxen, A. (2011). Fully Automated Preparation and Conjugation of N-Succinimidyl 4-[(18)F]Fluorobenzoate ([ (18)F]SFB) with RGD Peptide Using a GE FASTlab Synthesizer. Molecular Imaging and Biology. doi:10.1007/s11307-011-0470-x
Peer Reviewed verified by ORBi

Mercier, F., Paris, J., Kaisin, G., Thonon, D., Flagothier, J., Teller, N., Lemaire, C., & Luxen, A. (2011). General Method for Labeling siRNA by Click Chemistry with Fluorine-18 for the Purpose of PET Imaging. Bioconjugate Chemistry, 22 (1), 108-114. doi:10.1021/bc100263y
Peer Reviewed verified by ORBi

Balentova, E., Collet, C., Lamande-Langle, S., Chretien, F., Thonon, D., Aerts, J., Lemaire, C., Luxen, A., & Chapleur, Y. (2011). Synthesis and hydrolytic stability of novel 3-[18F]fluoroethoxybis(1-methylethyl)silyl]propanamine-based prosthetic groups. Journal of Fluorine Chemistry, 132 (4), 250-257. doi:10.1016/j.jfluchem.2011.01.011
Peer Reviewed verified by ORBi

Flagothier, J., Mercier, F., Kaisin, G., Thonon, D., Teller, N., & Luxen, A. (2011). Radiolabeling of modified siRNA by click chemistry with fluorine-18 for PET studies. In Journal of Labelled Compounds and Radiopharmaceuticals.
Peer reviewed

Vanasschen, C., Bouslimani, N., Thonon, D., & Desreux, J.-F. (2011). Gadolinium DOTA Chelates Featuring Alkyne Groups Directly Grafted on the Tetraaza Macrocyclic Ring: Synthesis, Relaxation Properties, "Click" Reaction, and High-Relaxivity Micelles. Inorganic Chemistry, 50 (18), 8946-8958. doi:10.1021/ic2010997
Peer Reviewed verified by ORBi

Kaisin, G., Flagothier, J., Mercier, F., Thonon, D., Paris, J., Kech, C., Lemaire, C., Plenevaux, A., & Luxen, A. (June 2010). Click chemistry : radiolabelling of oligonucleotides with fluorine- 18 for PET [Poster presentation]. FACS XIII - French American Chemical Society, Obernai, France.

Goblet, D., Thonon, D., Plenevaux, A., Lemaire, C., Defraiteur, C., Wouters, L., Franci, X., & Luxen, A. (30 May 2010). Automated radiosynthesis of [18F]MPPF derivatives for imaging 5-HT1A receptors [Poster presentation]. 5TH European Molecular Imaging Meeting, Warsaw, Poland.

Paris, J., Mercier, F., Thonon, D., Kaisin, G., Goblet, D., & Luxen, A. (27 May 2010). 18F labelling of Insulin via click chemistry [Poster presentation]. 5th European Molecular Imaging Mee ting – EMIM2010, Warsaw, Poland.

Aerts, J., Voccia, S., Lemaire, C., Giacomelli, F., Goblet, D., Thonon, D., Plenevaux, A., Warnock, G., & Luxen, A. (2010). Fast production of highly concentrated reactive [18F] fluoride for aliphatic and aromatic nucleophilic radiolabelling. Tetrahedron Letters, 51, 64-66. doi:10.1016/j.tetlet.2009.10.085
Peer Reviewed verified by ORBi

Thonon, D., Paris, J., Kech, C., Lemaire, C., & Luxen, A. (2009). PEPTIDE CLICK LABELLING WITH 1-(AZIDOMETHYL)-4-[18F]-FLUOROBENZENE AND REFERENCE COMPOUNDS SYNTHESIS ON SOLID SUPPORT. In Journal of Labelled Compounds and Radiopharmaceuticals (pp. 26). John Wiley & Sons Ltd.
Peer reviewed

Aerts, J., Voccia, S., Lemaire, C., Thonon, D., Plenevaux, A., & Luxen, A. (July 2009). Tertiary Alcohols to Avoid Evaporation in Fluorine-18 Labeling. Journal of Labelled Compounds and Radiopharmaceuticals, 52 (S1), 204.
Peer Reviewed verified by ORBi

Aerts, J., Voccia, S., Lemaire, C., Giacomelli, F., Goblet, D., Thonon, D., Plenevaux, A., & Luxen, A. (July 2009). Modified Non-Ionic Solid Supports: a Way to High Activity Fluorine-18 Radiochemistry in Microfluidic Devices. Journal of Labelled Compounds and Radiopharmaceuticals, 52 (S1), 12.
Peer Reviewed verified by ORBi

Flagothier, J., Mercier, F., Kaisin, G., Thonon, D., Lemaire, C., & Luxen, A. (29 May 2009). Universal solid support synthesis of modified oligonucleotides labeled by click chemistry for PET studies [Poster presentation]. 4th European Molecular Imaging Meeting of the ESMI, Barcelona, Spain.

Thonon, D., Paris, J., Kech, C., Lemaire, C., & Luxen, A. (26 March 2009). New Strategy for the Preparation of Clickable Peptides and Labeling with 1-(Azidomethyl)-4-[18F]-fluorobenzene for PET. Bioconjugate Chemistry, 20 (4), 817-823. doi:10.1021/bc800544p
Peer Reviewed verified by ORBi

Kaisin, G., Flagothier, J., Mercier, F., Thonon, D., Paris, J., Kech, C., Lemaire, C., Plenevaux, A., & Luxen, A. (18 March 2009). Click chemistry : radiolabelling of oligonucleotides with fluorine-18 for PET imaging [Poster presentation]. Learning Organic Synthesis Tremendously (LOST II), Namur, Belgium.

Thonon, D., Flagothier, J., Paris, J., Mercier, F., Kaisin, G., Kech, C., Lemaire, C., Plenevaux, A., & Luxen, A. (August 2008). 18F LABELING OF BIOMOLECULES USING CLICK CHEMISTRY FOR PET APPLICATIONS : SYNTHETIC DEVELOPMENTS. Drugs of the Future, 33 (A), 235.
Peer reviewed

Paris, J., Thonon, D., kech, C., Lemaire, C., & Luxen, A. (03 July 2008). Click chemistry for 18F labelling of bioactive compounds [Poster presentation]. 44èmes rencontres internationales de chimie thérapeutique : interfacing chemical biology, natural products and drug discovery, Angers, France.

Thonon, D., Kech, C., Lemaire, C., & Luxen, A. (2008). Click Chemistry Based Labeling of Biomolecules with 18F: a New Method to Produce PET Molecular Tracers [Poster presentation]. Biomedica Life Science Summit.

Vanasschen, C., Thonon, D., Lecomte, P., & Desreux, J.-F. (31 August 2007). Synthesis of high-relaxivity contrast agents for magnetic resonance imaging by "click" chemistry [Poster presentation]. Polymers: Last achievements and prospects, in honour of Professor Jérôme, Liège, Belgium.

Thonon, D. (2007). AGENTS CHELATEURS POLYFONCTIONNELS : SYNTHESES, BIOCONJUGAISONS ET EVALUATIONS PHYSICO-CHIMIQUES EN TANT QU’AGENTS DE CONTRASTE POUR L’IMAGERIE DE RESONANCE MAGNETIQUE [Doctoral thesis, Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/314858

Thonon, D., Jacques, V., & Desreux, J.-F. (2007). A gadolinium triacetic monoamide DOTA derivative with a methanethiosulfonate anchor group. Relaxivity properties and conjugation with albumin and thiolated particles. Contrast Media and Molecular Imaging, 2, 24-34. doi:10.1002/cmmi.121
Peer Reviewed verified by ORBi

Thonon, D., Paris, J., Jacques, V., Vanasschen, C., & Desreux, J.-F. (2007). Synthèse de chélateurs bifonctionnels en vue du développement d’agents de contraste pour l’IRM [Paper presentation]. French-Belgian Meeting on Organic Chemistry, 2007.

Thonon, D., Vanasschen, C., Paris, J., Jacques, V., & Desreux, J.-F. (2006). Ditopic Gadolinium containing MRI Contrast Agents: increasing relaxivity by self-assembly or by binding to macromolecules through disulfide links [Paper presentation]. COST Chemistry Action D18 Final Meeting « Lanthanide Chemistry for Diagnosis and Therapy ».

Thonon, D., Vanasschen, C., Paris, J., Jacques, V., & Desreux, J.-F. (2006). Routes to increase the relaxivity of contrast agents for MRI [Poster presentation]. French-Benelux Meeting on Magnetic Resonance.

Thonon, D., Vanasschen, C., & Desreux, J.-F. (2005). Ditopic Gadolinium-containing MRI Contrast Agents with Methanethiosulfonate Arms [Poster presentation]. fourth annual meeting of the Society for Molecular Imaging, Cologne, Germany.

Thonon, D., & Desreux, J.-F. (2004). SILICA NANOPARTICLE Gd(III)- DOTA CONJUGATE AS CONTRAST AGENTS FOR MAGNETIC RESONANCE IMAGING [Poster presentation]. COST Chemistry Action D18 “Lanthanide Chemistry for Diagnosis and Therapy, A Coruna, Spain.

Thonon, D., Paris, J., Humblet, J., Jacques, V., & Desreux, J.-F. (2003). Synthèse de ligands ditopiques en tant qu’agents de contraste pour l’imagerie de résonance magnétique [Poster presentation]. French-Belgian Meeting on Organic Chemistry, 2003.

Desreux, J.-F., Paris, J., Thonon, D., Humblet, V., & Jacques, V. (2003). Fe(II) and Fe(III) specific detection by nuclear magnetic relaxation methods with self-assembling poly-heterometallic gadolinium-containing ligands [Poster presentation]. Conférences Jacques Monod: New In Vivo Imaging Modalities, Roskoff, France.

Thonon, D., Paris, J., Jacques, V., & Luxen, A. (2002). Lanthanide DOTA chelates bearing a methanethiosulfonate group as contrast agents for magnetic resonance imaging.

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