Publications and communications of Thibault Gendron

Rizzoli, E., Bahri, M. A., Dammicco, S., Degueldre, C., Tutunaru, A.-C., Garigliany, M.-M., Gérardy, M., Bolen, G., Withofs, N., Gendron, T., & Clercx, C. (15 January 2026). Evaluation of [18F]FAPI-74 PET/CT in healthy dogs and in West Highland white terriers with canine idiopathic pulmonary fibrosis: a pilot study. Veterinary Journal, 315, 106565. doi:10.1016/j.tvjl.2026.106565

Storms, W., Celen, S., Maes, J., Serdons, K., Goffin, K., De Groot, T., Trump, L., Warnier, C., Gendron, T., Gérardy, R., Van Laere, K., Deroose, C. M., Kleynhans, J., & Cleeren, F. (14 December 2025). cGMP-compliant high-yield automated production of [18F]AlF-FAPI-74: optimization of quality control and evaluation of molar dose impact. EJNMMI Radiopharmacy and Chemistry, 11 (1), 3. doi:10.1186/s41181-025-00411-1

Kribii, R., Lê, D., Dammicco, S., & Gendron, T. (04 December 2025). Synthesis of Radiotracers to Image Neuroinflammation in Alzheimer’s Disease [Poster presentation]. Merck Organic Chemistry Symposium 2025, Blankenberge, Belgium.

Farooq, R., Gendron, T., Edwards, R. S., & Witney, T. H. (17 January 2025). Compact and cGMP-compliant automated synthesis of [18F]FSPG on the Trasis AllinOne™. EJNMMI Radiopharmacy and Chemistry, 10 (1), 2. doi:10.1186/s41181-024-00322-7

Gendron, T., Lanfranchi, D. A., Wenzel, N. I., Kessedjian, H., Jannack, B., Maes, L., Cojean, S., Müller, T. J. J., Loiseau, P. M., & Davioud-Charvet, E. (04 April 2024). Chemoselective Synthesis and Anti-Kinetoplastidal Properties of 2,6-Diaryl-4H-tetrahydro-thiopyran-4-one S-Oxides: Their Interplay in a Cascade of Redox Reactions from Diarylideneacetones. Molecules, 29 (7), 1620. doi:10.3390/molecules29071620

Paty, L.-P., Degueldre, S., Provost, C., Schmitt, C., Trump, L., Fouque, J., Vriamont, C., Valla, F., Gendron, T., & Madar, O. (2024). Development of a versatile [68Ga]Ga-FAPI-46 automated synthesis suitable to multi-elutions of germanium-68/gallium-68 generators. Frontiers in Chemistry, 12, 1411312. doi:10.3389/fchem.2024.1411312

Pacelli, A., Zarrad, F., Warnier, C., Gendron, T., Otabashi, M., Vriamont, C., Jackson, A., Fendler, W. P., Herrmann, K., & Nader, M. (19 July 2023). Fully Automated, High-Dose Radiosynthesis of [18F]PARPi. Pharmaceuticals, 16 (7), 1024. doi:10.3390/ph16071024

Gendron, T., Destro, G., Straathof, N. J. W., Sap, J. B. I., Guibbal, F., Vriamont, C., Caygill, C., Atack, J. R., Watkins, A. J., Marshall, C., Hueting, R., Warnier, C., Gouverneur, V., & Tredwell, M. (20 March 2022). Multi-patient dose synthesis of [18F]Flumazenil via a copper-mediated 18F-fluorination. EJNMMI Radiopharmacy and Chemistry, 7 (1), 5. doi:10.1186/s41181-022-00158-z

Galovic, M., Erlandsson, K., Fryer, T. D., Hong, Y. T., Manavaki, R., Sari, H., Chetcuti, S., Thomas, B. A., Fisher, M., Sephton, S., Canales, R., Russell, J. J., Sander, K., Årstad, E., Aigbirhio, F. I., Groves, A. M., Duncan, J. S., Thielemans, K., Hutton, B. F., ... Gendron, T. (15 August 2021). Validation of a combined image derived input function and venous sampling approach for the quantification of [18F]GE-179 PET binding in the brain. NeuroImage, 237, 118194. doi:10.1016/j.neuroimage.2021.118194

Sander, K., Gendron, T., Cybulska, K. A., Sirindil, F., Zhou, J., Kalber, T. L., Lythgoe, M. F., Kurzawinski, T. R., Brown, M. J., Williams, B., & Årstad, E. (08 July 2021). Development of [18F]AldoView as the First Highly Selective Aldosterone Synthase PET Tracer for Imaging of Primary Hyperaldosteronism. Journal of Medicinal Chemistry, 64 (13), 9321 - 9329. doi:10.1021/acs.jmedchem.1c00539

Gendron, T., Pereira, R., Abdi, H. Y., Witney, T. H., & Årstad, E. (03 January 2020). Iron(II)/Persulfate Mediated Newman-Kwart Rearrangement. Organic Letters, 22 (1), 274 - 278. doi:10.1021/acs.orglett.9b04280

Glaser, M., Rajkumar, V., Diocou, S., Gendron, T., Yan, R., Sin, P. K. B., Sander, K., Carroll, L., Pedley, R. B., Aboagye, E. O., Witney, T. H., & Årstad, E. (17 December 2019). One-Pot Radiosynthesis and Biological Evaluation of a Caspase-3 Selective 5-[123,125I]iodo-1,2,3-triazole derived Isatin SPECT Tracer. Scientific Reports, 9 (1), 19299. doi:10.1038/s41598-019-55992-0

Bascuñana, P.* , Gendron, T.* , Sander, K., Jahreis, I., Polyak, A., Ross, T. L., Bankstahl, M., Arstad, E., & Bankstahl, J. P. (November 2019). Ex vivo characterization of neuroinflammatory and neuroreceptor changes during epileptogenesis using candidate positron emission tomography biomarkers. Epilepsia, 60 (11), 2325 - 2333. doi:10.1111/epi.16353
* These authors have contributed equally to this work.

Greenwood, H. E., McCormick, P. N., Gendron, T., Glaser, M., Pereira, R., Maddocks, O. D. K., Sander, K., Zhang, T., Koglin, N., Lythgoe, M. F., Årstad, E., Hochhauser, D., & Witney, T. H. (15 April 2019). Measurement of Tumor Antioxidant Capacity and Prediction of Chemotherapy Resistance in Preclinical Models of Ovarian Cancer by Positron Emission Tomography. Clinical Cancer Research, 25 (8), 2471 - 2482. doi:10.1158/1078-0432.CCR-18-3423

McCormick, P. N., Greenwood, H. E., Glaser, M., Maddocks, O. D. K., Gendron, T., Sander, K., Gowrishankar, G., Hoehne, A., Zhang, T., Shuhendler, A. J., Lewis, D. Y., Berndt, M., Koglin, N., Lythgoe, M. F., Gambhir, S. S., Årstad, E., & Witney, T. H. (15 February 2019). Assessment of Tumor Redox Status through (S)-4-(3-[18F]fluoropropyl)-L-Glutamic Acid PET Imaging of System xc - Activity. Cancer Research, 79 (4), 853 - 863. doi:10.1158/0008-5472.CAN-18-2634

Pereira, R., Gendron, T., Sanghera, C., Greenwood, H. E., Newcombe, J., McCormick, P. N., Sander, K., Topf, M., Årstad, E., & Witney, T. H. (11 February 2019). Mapping Aldehyde Dehydrogenase 1A1 Activity using an [18F]Substrate-Based Approach. Chemistry: a European journal, 25 (9), 2345 - 2351. doi:10.1002/chem.201805473

Gendron, T., Sander, K., Cybulska, K., Benhamou, L., Sin, P., Khan, A., Wood, M., Porter, M., & Årstad, E. (August 2018). Ring-Closing Synthesis of Dibenzothiophene Sulfonium Salts and Their Use as Leaving Groups for Aromatic 18F-Fluorination. Journal of the American Chemical Society, 140 (35), 11125–11132. doi:10.1021/jacs.8b06730

Viira, B., Gendron, T., Lanfranchi, D. A., Cojean, S., Horvath, D., Marcou, G., Varnek, A., Maes, L., Maran, U., Loiseau, P. M., & Davioud-Charvet, E. (29 June 2016). In Silico Mining for Antimalarial Structure-Activity Knowledge and Discovery of Novel Antimalarial Curcuminoids. Molecules, 21 (7), 853. doi:10.3390/molecules21070853

Sander, K., Galante, E., Gendron, T., Yiannaki, E., Patel, N., Kalber, T. L., Badar, A., Robson, M., Johnson, S. P., Bauer, F., Mairinger, S., Stanek, J., Wanek, T., Kuntner, C., Kottke, T., Weizel, L., Dickens, D., Erlandsson, K., Hutton, B. F., ... Årstad, E. (13 August 2015). Development of Fluorine-18 Labeled Metabolically Activated Tracers for Imaging of Drug Efflux Transporters with Positron Emission Tomography. Journal of Medicinal Chemistry, 58 (15), 6058 - 6080. doi:10.1021/acs.jmedchem.5b00652

Gendron, T., Sander, K., Cybulska, K., Gray, V., & Arstad, E. (21 May 2015). Dibenzothiophene sulfonium salts as leaving groups for aromatic [18F] fluorination-exemplified by highly efficient direct labeling of the mGluR5 PET tracer [18F] FPEB. Journal of Labelled Compounds and Radiopharmaceuticals, 58, 8-S8. doi:10.1002/jlcr.3302_1

Sander, K., Gendron, T., Yiannaki, E., Cybulska, K., Kalber, T. L., Lythgoe, M., & Arstad, E. (15 May 2015). Functionalized Triarylsulfonium Salts for Aromatic [18F] Fluorination of Drug-like Small Molecules. Journal of Labelled Compounds and Radiopharmaceuticals, 58, 4-S4.

Sander, K., Gendron, T., Yiannaki, E., Cybulska, K., Kalber, T., Lythgoe, M., & Årstad, E. (April 2015). Sulfonium Salts as Leaving Groups for Aromatic Labelling of Drug-like Small Molecules with Fluorine-18. Scientific Reports, 5 (1). doi:10.1038/srep09941

Gendron, T., Davioud-Charvet, E., & Müller, T. J. J. (19 November 2012). Versatile synthesis of dissymmetric diarylideneacetones via a palladium-catalyzed coupling-isomerization reaction. Synthesis, 44 (24), 3829 - 3835. doi:10.1055/s-0032-1316811