Publications and communications of Thibault Gendron

Pacelli, A., Zarrad, F., Warnier, C., Gendron, T., Otabashi, M., Vriamont, C., Jackson, A., Fendler, W. P., Herrmann, K., & Nader, M. (19 July 2023). Fully Automated, High-Dose Radiosynthesis of [18F]PARPi. Pharmaceuticals, 16 (7), 1024. doi:10.3390/ph16071024

Gendron, T., Destro, G., Straathof, N. J. W., Sap, J. B. I., Guibbal, F., Vriamont, C., Caygill, C., Atack, J. R., Watkins, A. J., Marshall, C., Hueting, R., Warnier, C., Gouverneur, V., & Tredwell, M. (20 March 2022). Multi-patient dose synthesis of [18F]Flumazenil via a copper-mediated 18F-fluorination. EJNMMI Radiopharmacy and Chemistry, 7 (1), 5. doi:10.1186/s41181-022-00158-z

Galovic, M., Erlandsson, K., Fryer, T. D., Hong, Y. T., Manavaki, R., Sari, H., Chetcuti, S., Thomas, B. A., Fisher, M., Sephton, S., Canales, R., Russell, J. J., Sander, K., Årstad, E., Aigbirhio, F. I., Groves, A. M., Duncan, J. S., Thielemans, K., Hutton, B. F., ... Gendron, T. (15 August 2021). Validation of a combined image derived input function and venous sampling approach for the quantification of [18F]GE-179 PET binding in the brain. NeuroImage, 237, 118194. doi:10.1016/j.neuroimage.2021.118194

Sander, K., Gendron, T., Cybulska, K. A., Sirindil, F., Zhou, J., Kalber, T. L., Lythgoe, M. F., Kurzawinski, T. R., Brown, M. J., Williams, B., & Årstad, E. (08 July 2021). Development of [18F]AldoView as the First Highly Selective Aldosterone Synthase PET Tracer for Imaging of Primary Hyperaldosteronism. Journal of Medicinal Chemistry, 64 (13), 9321 - 9329. doi:10.1021/acs.jmedchem.1c00539

Gendron, T., Pereira, R., Abdi, H. Y., Witney, T. H., & Årstad, E. (03 January 2020). Iron(II)/Persulfate Mediated Newman-Kwart Rearrangement. Organic Letters, 22 (1), 274 - 278. doi:10.1021/acs.orglett.9b04280

Glaser, M., Rajkumar, V., Diocou, S., Gendron, T., Yan, R., Sin, P. K. B., Sander, K., Carroll, L., Pedley, R. B., Aboagye, E. O., Witney, T. H., & Årstad, E. (17 December 2019). One-Pot Radiosynthesis and Biological Evaluation of a Caspase-3 Selective 5-[123,125I]iodo-1,2,3-triazole derived Isatin SPECT Tracer. Scientific Reports, 9 (1), 19299. doi:10.1038/s41598-019-55992-0

Bascuñana, P.* , Gendron, T.* , Sander, K., Jahreis, I., Polyak, A., Ross, T. L., Bankstahl, M., Arstad, E., & Bankstahl, J. P. (November 2019). Ex vivo characterization of neuroinflammatory and neuroreceptor changes during epileptogenesis using candidate positron emission tomography biomarkers. Epilepsia, 60 (11), 2325 - 2333. doi:10.1111/epi.16353

Gendron, T., Sander, K., Cybulska, K., Benhamou, L., Sin, P. K. B., Khan, A., Wood, M., Porter, M. J., & Årstad, E. (14 June 2019). Dibenzothiophene sulfonium salts as novel leaving groups for aromatic 18F-fluorination [Paper presentation]. Royal Society of Chemistry Radiochemistry Group Young Researchers Meeting, London, United Kingdom.

Greenwood, H. E., McCormick, P. N., Gendron, T., Glaser, M., Pereira, R., Maddocks, O. D. K., Sander, K., Zhang, T., Koglin, N., Lythgoe, M. F., Årstad, E., Hochhauser, D., & Witney, T. H. (15 April 2019). Measurement of Tumor Antioxidant Capacity and Prediction of Chemotherapy Resistance in Preclinical Models of Ovarian Cancer by Positron Emission Tomography. Clinical Cancer Research, 25 (8), 2471 - 2482. doi:10.1158/1078-0432.CCR-18-3423

McCormick, P. N., Greenwood, H. E., Glaser, M., Maddocks, O. D. K., Gendron, T., Sander, K., Gowrishankar, G., Hoehne, A., Zhang, T., Shuhendler, A. J., Lewis, D. Y., Berndt, M., Koglin, N., Lythgoe, M. F., Gambhir, S. S., Årstad, E., & Witney, T. H. (15 February 2019). Assessment of Tumor Redox Status through (S)-4-(3-[18F]fluoropropyl)-L-Glutamic Acid PET Imaging of System xc - Activity. Cancer Research, 79 (4), 853 - 863. doi:10.1158/0008-5472.CAN-18-2634

Pereira, R., Gendron, T., Sanghera, C., Greenwood, H. E., Newcombe, J., McCormick, P. N., Sander, K., Topf, M., Årstad, E., & Witney, T. H. (11 February 2019). Mapping Aldehyde Dehydrogenase 1A1 Activity using an [18F]Substrate-Based Approach. Chemistry, 25 (9), 2345 - 2351. doi:10.1002/chem.201805473

Gendron, T., Sander, K., Cybulska, K., Benhamou, L., Sin, P. K. B., Khan, A., Wood, M., Porter, M. J., & Årstad, E. (12 November 2018). Dibenzothiophene sulfonium salts as novel leaving groups for aromatic 18F-fluorination [Paper presentation]. Preclinical Nuclear Imaging Symposium (PNI), London, United Kingdom.

Gendron, T., Sander, K., Cybulska, K., Benhamou, L., Sin, P., Khan, A., Wood, M., Porter, M., & Årstad, E. (August 2018). Ring-Closing Synthesis of Dibenzothiophene Sulfonium Salts and Their Use as Leaving Groups for Aromatic 18F-Fluorination. Journal of the American Chemical Society, 140 (35), 11125–11132. doi:10.1021/jacs.8b06730

Glaser, M., Gendron, T., McCormick, P., Berndt, M., Koglin, N., Sander, K., Witney, T., & Arstad, E. (14 May 2017). Automated Radiosynthesis and Biological Evaluation of [18F]FSPG. Journal of Labelled Compounds and Radiopharmaceuticals, 60, 7-110. doi:10.1002/jlcr.3507

Ellen Forty, Ilan Azuelos, Tammy Kalber, Gendron, T., May Zaw-Thin, Giovanni Vitulli, John Barrett, Dimitrios Anastasiou, Paul Mercer, Andy Blanchard, & Rachel Chambers. (2017). LSC - 2017 - Targeting glucose metabolism in experimental lung injury and fibrosis. European Respiratory Journal, 50 (suppl 61), 3470. doi:10.1183/1393003.congress-2017.PA3470

Sander, K., Lashley, T., Gami, P., Gendron, T., Lythgoe, M. F., Rohrer, J. D., Schott, J. M., Revesz, T., Fox, N. C., & Årstad, E. (November 2016). Characterization of tau positron emission tomography tracer [18F]AV-1451 binding to postmortem tissue in Alzheimer's disease, primary tauopathies, and other dementias. Alzheimer's and Dementia: the Journal of the Alzheimer's Association, 12 (11), 1116 - 1124. doi:10.1016/j.jalz.2016.01.003

Gendron, T., Sander, K., & Arstad, E. (26 October 2016). Tracer Development for MAO-B Imaging of Epileptogenesis – An Update [Paper presentation]. EPITARGET General Assembly Meeting, Marseilles, France.

Viira, B., Gendron, T., Lanfranchi, D. A., Cojean, S., Horvath, D., Marcou, G., Varnek, A., Maes, L., Maran, U., Loiseau, P. M., & Davioud-Charvet, E. (29 June 2016). In Silico Mining for Antimalarial Structure-Activity Knowledge and Discovery of Novel Antimalarial Curcuminoids. Molecules, 21 (7), 853. doi:10.3390/molecules21070853

Gendron, T., Sander, K., Cybulska, K., Glaser, M., & Arstad, E. (23 September 2015). Development of Radiolabeled Tracers for Imaging of Epileptogenesis [Paper presentation]. EPITARGET General Assembly Meeting, Milano, Italy.

Gendron, T., Sander, K., Cybulska, K., Gray, V., & Arstad, E. (02 September 2015). Ring-closing synthesis of dibenzothiophene sulfonium salts and their use as precursors for aromatic [18F]fluorination – Application to direct labeling of the mGluR5 PET tracer [18F]FPEB [Paper presentation]. World Molecular Imaging Congress 2015, Honolulu, United States.

Sander, K., Galante, E., Gendron, T., Yiannaki, E., Patel, N., Kalber, T. L., Badar, A., Robson, M., Johnson, S. P., Bauer, F., Mairinger, S., Stanek, J., Wanek, T., Kuntner, C., Kottke, T., Weizel, L., Dickens, D., Erlandsson, K., Hutton, B. F., ... Årstad, E. (13 August 2015). Development of Fluorine-18 Labeled Metabolically Activated Tracers for Imaging of Drug Efflux Transporters with Positron Emission Tomography. Journal of Medicinal Chemistry, 58 (15), 6058 - 6080. doi:10.1021/acs.jmedchem.5b00652

Gendron, T., Sander, K., Cybulska, K., Gray, V., & Arstad, E. (21 May 2015). Dibenzothiophene sulfonium salts as leaving groups for aromatic [18F] fluorination-exemplified by highly efficient direct labeling of the mGluR5 PET tracer [18F] FPEB. Journal of Labelled Compounds and Radiopharmaceuticals, 58, 8-S8. doi:10.1002/jlcr.3302_1

Sander, K., Gendron, T., Yiannaki, E., Cybulska, K., Kalber, T. L., Lythgoe, M., & Arstad, E. (15 May 2015). Functionalized Triarylsulfonium Salts for Aromatic [18F] Fluorination of Drug-like Small Molecules. Journal of Labelled Compounds and Radiopharmaceuticals, 58, 4-S4.

Sander, K., Gendron, T., Yiannaki, E., Cybulska, K., Kalber, T., Lythgoe, M., & Årstad, E. (April 2015). Sulfonium Salts as Leaving Groups for Aromatic Labelling of Drug-like Small Molecules with Fluorine-18. Scientific Reports, 5 (1). doi:10.1038/srep09941

Gendron, T., Kessedjian, H., Davioud-Charvet, E., & Lanfranchi, D. A. (March 2015). Diastereoselective Synthesis of 2,6-Diaryltetrahydrothiopyran-4-ones by Phase-Transfer Catalysis. European Journal of Organic Chemistry, 2015 (8), 1790 - 1796. doi:10.1002/ejoc.201403516

Gendron, T., Lanfranchi, D. A., & Davioud-Charvet, E. (2013). Redox-Active Agents in Reactions Involving the Trypanothione/Trypanothione Reductase-based System to Fight Kinetoplastidal Parasites. In Trypanosomatid Diseases: Molecular Routes to Drug Discovery. Wiley-VCH. doi:10.1002/9783527670383.ch22

Gendron, T., Lanfranchi, D. A., & Davioud-Charvet, E. (07 February 2013). Synthèse et évaluation de prodrogues de diarylidèneacétones à activité antiparasitaire [Paper presentation]. Young Research Fellow Meeting, Romainville, France.

Gendron, T., Davioud-Charvet, E., & Müller, T. J. J. (19 November 2012). Versatile synthesis of dissymmetric diarylideneacetones via a palladium-catalyzed coupling-isomerization reaction. Synthesis, 44 (24), 3829 - 3835. doi:10.1055/s-0032-1316811

Gendron, T., Lanfranchi, D. A., & Davioud-Charvet, E. (29 March 2012). Synthèse diastéréosélective de tetrahydrothiopyran-4-ones comme prodrogues de dibenzylidènes acétones à activité antiparasitaire [Paper presentation]. SCF Grand Est, Reims, France.

Gendron, T., Lanfranchi, D. A., & Davioud-Charvet, E. (22 November 2010). Discovery and optimization of a new palladium-catalyzed methodology for the synthesis of substituted dibenzylidenacetones [Paper presentation]. New Trends in Infectious Disease Research, Ellwangen, Germany.