Publications and communications of Rebekah Crake

Crake, R., Kiweler, N., Thiry, M., Peulen, O., Blomme, A., Meiser, J., Ambrogio, C., Santamaria, D., Cataldo, D., & Nokin, M.-J. (June 2023). Targeting metabolic adaptations in drug tolerant BRAFV600E mutant NSCLC [Poster presentation]. EACR 2023, Torino, Italy.

Crake, R., Gasmi, I., Dehaye, J., Lardinois, F., Peiffer, R., Maloujahmoum, N., Agirman, F., KOOPMANSCH, B., D’Haene, N., Azurmendi Senar, O., Arsenijevic, T., Lambert, F., Peulen, O., Van Laethem, J.-L., & Bellahcene, A. (17 May 2023). Resistance to Gemcitabine in Pancreatic Cancer Is Connected to Methylglyoxal Stress and Heat Shock Response. Cells, 12 (10), 1414. doi:10.3390/cells12101414

Dube, G., Tiamiou, A., Bizet, M., Boumahd, Y., Gasmi, I., Crake, R., Bellier, J., Nokin, M.-J., Calonne, E., Deplus, R., Wissocq, T., Peulen, O., Castronovo, V., Fuks, F., & Bellahcene, A. (31 March 2023). Methylglyoxal: a novel upstream regulator of DNA methylation. Journal of Experimental and Clinical Cancer Research, 42 (1), 78. doi:10.1186/s13046-023-02637-w

Lardinois, F., Crake, R., Bellier, J., Vara Messler, M., Richiardone, E., Peulen, O., Corbet, C., & Bellahcene, A. (21 February 2023). Role of methylglyoxal stress acquired resistance to cetuximab in quadruple wild-type colorectal cancer [Poster presentation]. Drugging and Regulating the MAP Kinase Pathway.

Peiffer, R., Boumahd, Y., Gullo, C., Crake, R., Letellier, E., Bellahcene, A., & Peulen, O. (22 December 2022). Cancer-Associated Fibroblast Diversity Shapes Tumor Metabolism in Pancreatic Cancer. Cancers, 15 (1), 61. doi:10.3390/cancers15010061

Lardinois, F., Crake, R., Bellier, J., Vara Messler, M., Richiardone, E., Peulen, O., Corbet, C., & Bellahcene, A. (30 September 2022). Role of methylglyoxal stress in acquired resistance to EGFR-targeted therapy in quadruple wild-type colorectal cancer [Poster presentation]. BACR - Belgian Association for Cancer Research, Ghent, Belgium.

Lardinois, F., Crake, R., Bellier, J., Vara Messler, M., Richiardone, E., Peulen, O., Corbet, C., & Bellahcene, A. (09 September 2022). Methylglyoxal Stress and Acquired Resistance to EGFR-Targeted Therapy in Colorectal Cancer [Poster presentation]. INTERUNIVERSITY PHD STUDENT DAY, Namur, Belgium.

Crake, R., Burgess, E. R., Wiggins, G. A. R., Magon, N. J., Das, A. B., Vissers, M. C. M., Morrin, H. R., Royds, J. A., Slatter, T. L., Robinson, B. A., Phillips, E., & Dachs, G. U. (01 September 2022). Ascorbate content of clinical glioma tissues is related to tumour grade and to global levels of 5-hydroxymethyl cytosine. Scientific Reports, 12 (1), 14845. doi:10.1038/s41598-022-19032-8

Lardinois, F., Crake, R., Bellier, J., Vara Messler, M., Richiardone, E., Peulen, O., Corbet, C., & Bellahcene, A. (22 June 2022). Acquired resistance to Cetuximab in quadruple wild-type colorectal cancer: role of methylglyoxal stress [Poster presentation]. EACR - European Association for Cancer Research, Séville, Spain.

Crake, R. (20 June 2022). Contribution of methylglyoxal stress to acquired resistance to Gemcitabine in pancreatic ductal adenocarcinoma [Poster presentation]. EACR 2022, Seville, Spain.

Burgess, E. R., Crake, R., Phillips, E., Morrin, H. R., Royds, J. A., Slatter, T. L., Wiggins, G. A. R., Vissers, M. C. M., Robinson, B. A., & Dachs, G. U. (2022). Increased Ascorbate Content of Glioblastoma Is Associated With a Suppressed Hypoxic Response and Improved Patient Survival. Frontiers in Oncology, 12, 829524. doi:10.3389/fonc.2022.829524

Lardinois, F., Crake, R., Bellier, J., Vara Messler, M., Richiardone, E., Peulen, O., Corbet, C., & Bellahcene, A. (December 2021). Acquired resistance to EGFR-targeted therapy in quadruple wild-type colorectal cancer: role of methylglyoxal stress [Poster presentation]. GIGA-Cancer Day, Liège, Belgium.

Crake, R. (14 October 2021). Role of MG-stress in PDAC resistance to gemcitabine [Paper presentation]. GIGA-Cancer Day.

Crake, R., Agirman, F., Arsenijevic, T., Maloujahmoum, N., Peulen, O., Van Laethem, J.-L., & Bellahcene, A. (14 October 2021). Improving pancreatic cancer response to gemcitabine by overcoming methylglyoxal driven suppression of AMPK [Poster presentation]. GIGA-Cancer Day, Liege, Belgium.

Crake, R.* , Burgess, E.* , Royds, J., Phillips, E., Vissers, M., & Dachs, G. (25 March 2021). The role of 2-oxoglutarate dependent dioxygenases in gliomas and glioblastomas: hypoxic response and epigenetic reprogramming. Frontiers in Oncology, 11. doi:10.3389/fonc.2021.619300
* These authors have contributed equally to this work.

Crake, R., Strother, M., Phillips, E., Doogue, M., Zhang, M., Frampton, C., Robinson, B., & Currie, M. (11 March 2021). Influence of serum inflammatory cytokines on cytochrome P450 drug metabolising activity during breast cancer chemotherapy: a patient feasibility study. Scientific Reports, 11 (1), 5648. doi:10.1038/s41598-021-85048-1

Crake, R., Phillips, E., Kleffmann, T., Morrin, H., Strother, M., Robinson, B., & Currie, M. (October 2020). Impact of PGK1 overexpression on breast cancer cells in vitro [Poster presentation]. New Zealand Society of Oncology Virtual Conference, New Zealand.

Crake, R. (2020). Local and systemic effects of adipocyte-secreted factors in breast cancer [Doctoral thesis, University of Otago Christchurch]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/260455

Crake, R., Phillips, E., Kleffmann, T., Morrin, H., Strother, M., Robinson, B., & Currie, M. (2020). Impact of PGK1 overexpression on breast cancer cells in vitro [Poster presentation]. EACR-AACR-ASPIC 2020 Conference: Tumour Microenvironment.

Phillips, E., Jones, M., Crake, R., Morrin, H., Pilbrow, A., & Currie, M. (2020). Adipocyte-driven progression in breast cancer: A role for microRNAs? [Poster presentation]. EACR-AACR-ASPIC 2020 Conference: Tumour Microenvironment.

Crake, R., Phillips, E., Kleffmann, T., & Currie, M. (03 September 2019). Co-culture With Human Breast Adipocytes Differentially Regulates Protein Abundance in Breast Cancer Cells. Cancer Genomics and Proteomics, 16 (5), 319–332. doi:10.21873/cgp.20137

Crake, R., Strother, M., Morrin, H., Smith, A., Phillips, E., Robinson, B., & Currie, M. (2019). Assessing the impact of obesity-related inflammation and physical activity on the function of CYP450 enzymes in women with breast cancer [Paper presentation]. University of Otago Student Research Symposium: Te Wānaka Rakahau: Ākoka.

Crake, R., Strother, M., Morrin, H., Smith, A., Phillips, E., Robinson, B., & Currie, M. (2019). An exploratory patient study to assess obesity-related inflammation, physical activity and liver CYP450 enzyme function in women with breast cancer [Poster presentation]. New Zealand Society of Oncology Conference 2019.

Phillips, E., Jones, M., Crake, R., Morrin, H., Pilbrow, A., & Currie, M. (2019). Identification of microRNAs that contribute to adipocyte-driven progression in breast cancer cell lines [Paper presentation]. New Zealand Society of Oncology Conference 2019.

Crake, R., Phillips, E., Morrin, H., Strother, M., Robinson, B., & Currie, M. (2018). Transwell co-culture with human breast adipocytes alters the proteome expression profiles of mcf-7 and mda-mb-231 human breast cancer cells [Paper presentation]. EACR 2018, Amsterdam, Netherlands. doi:10.1136/esmoopen-2018-EACR25.268

Crake, R., Strother, M., Morrin, H., Smith, A., Phillips, E., Robinson, B., & Currie, M. (2018). An exploratory breast cancer patient study to assess the impact of obesity-related inflammation and physical activity on chemotherapy drug metabolism [Paper presentation]. New Zealand Society of Oncology Conference 2018.

Currie, M., Phillips, E., Crake, R., Kleffmann, T., Wise, J., Lim, K., Morrin, H., & Woodfield, T. (2018). 2D and 3D co-culture models to study interactions between human breast adipocytes and breast cancer cells [Paper presentation]. Australian Biospecimen Network Association Conference 2018.

Crake, R., Kleffmann, T., Morrin, H., Strother, M., Robinson, B., Phillips, E., & Currie, M. (2017). Local effects of cancer associated adipocytes (CAA) on breast cancer cell proteomes [Paper presentation]. New Zealand Society of Oncology Conference 2017.

Crake, R. (2015). Exploring Molecular Links between Obesity and Breast Cancer [Specialised master, University of Otago Christchurch]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/298461

Crake, R., Wiggins, G., Morrin, H., Phillips, E., Currie, M., & Walker, L. (2015). Exploring molecular links between obesity and breast cancer [Poster presentation]. New Zealand Society of Oncology Conference 2015.