Dumoulin, M., Morales Yánez, F. J., Redeghieri, P., Vanbever, R., Vanderstraeten, J., Leal, T., Mottais, A., Muyldermans, S., & Vincke, C. (02 January 2025). Single-domain antibody for the inhibition of neutrophil elastase activity. |
Redeghieri, P., Moray, J., Kerff, F., Gohy, S., Leal, T., Muyldermans, S., Vanbever, R., Morales Yánez, F. J.* , & Dumoulin, M.*. (27 November 2024). Enzymatic, structural, and biophysical characterization of a single-domain antibody (VHH) selectively and tightly inhibiting neutrophil elastase and exhibiting favorable developability properties. Protein Science: A Publication of the Protein Society, 33 (12), 5227. doi:10.1002/pro.5227 * These authors have contributed equally to this work. |
Redeghieri, P., Moray, J., Kerff, F., Mottais, A., Leal, T., Gohy, S., Muylderman, S., Morales Yánez, F. J., & Dumoulin, M. (15 November 2024). NbE201: a single-domain antibody fragment to inhibit neutrophil elastase and reduce inflammation [Paper presentation]. SFMBBM - PhD Day 2024 (UNamur), Namur, Belgium. |
Redeghieri, P., Moray, J., Kerff, F., Mottais, A., Vincke, C., Leal, T., Gohy, S., Morales Yánez, F. J.* , & Dumoulin, M.*. (16 September 2024). NbE201: a Single-Domain Antibody fragment to Inhibit Neutrophil Elastase and reduce inflammation [Paper presentation]. FEBS Wokshop 2024, Proteolysis: at the interface between health and disease, Bled, Slovenia. * These authors have contributed equally to this work. |
Redeghieri, P., Moray, J., Kerff, F., Mottais, A., Vandersraeten, J., Vincke, C., Leal, T., Gohy, S., Muylderman, S., Vanbever, R., Morales Yánez, F. J.* , & Dumoulin, M.*. (09 June 2024). A Single-Domain Antibody Fragment (VHH) Inhibiting Neutrophil Elastase for the Treatment of Inflammatory Lung Diseases [Poster presentation]. Proteolytic Enzymes and Their Inhibitors (GRS) Gordon Research Seminar. * These authors have contributed equally to this work. |
Redeghieri, P., Moray, J., Kerff, F., Leal, T., Muyldermans, S., Vanbever, R., Morales Yánez, F. J.* , & Dumoulin, M.*. (30 May 2024). ENZYMATIC, STRUCTURAL AND BIOPHYSICAL CHARACTERIZATION OF A SINGLE DOMAIN ANTIBODY (VHH) SELECTIVELY AND TIGHTLY INHIBITING NEUTROPHIL ELASTASE AND EXHIBITING FAVORABLE DEVELOPABILITY PROPERTIES [Paper presentation]. Interuniversity PhD Student Day, Louvain-la-Neuve, Belgium. * These authors have contributed equally to this work. |
Redeghieri, P., Moray, J., Kerff, F., Mottais, A., Vanderstraeten, J., Vincke, C., Leal, T., Gohy, S., Muylderman, S., Vanbever, R., Morales Yánez, F. J.* , & Dumoulin, M.*. (23 May 2024). A single-domain antibody fragment (VHH) inhibiting neutrophil elastase for the treatment of inflammatory lung diseases [Paper presentation]. InBioS DAY, Liège, Belgium. * These authors have contributed equally to this work. |
Redeghieri, P., Moray, J., Kerff, F., Vincke, C., Leal, T., Muyldermans, S., Vanbever, R., Morales Yánez, F. J., & Dumoulin, M. (18 September 2023). In vitro characterisation of a Nanobody selectively inhibiting human Neutrophil elastase [Poster presentation]. Single domain antibodies conference 2023, Paris, France. |
Cawez, F., Mercuri, P., Piccirilli, A., Perilli, M., Morales Yánez, F. J., Dumoulin, M., & Galleni, M. (02 June 2023). Selection and characterization of anti-NDM-1 nanobodies [Poster presentation]. 14 th Beta-Lactam and beta-lactamase meeting, L'Aquila, Italy. |
Cawez, F., Mercuri, P., Morales Yánez, F. J., Maalouf, R., Vandevenne, M., Kerff, F., Guérin, V., Mainil, J., Thiry, D., Saulmont, M., Vanderplasschen, A., Lafaye, P., Aymé, G., Bogaerts, P., Dumoulin, M., & Galleni, M. (2023). Development of Nanobodies as Theranostic Agents against CMY-2-Like Class C b-Lactamases. Antimicrobial Agents and Chemotherapy. doi:10.1128/aac.01499-22 |
Rondon, A., Mahri, S., Morales Yanes, F. J., Dumoulin, M., & Vanbever, R. (2021). Protein Engineering Strategies for Improved Pharmacokinetics. Advanced Functional Materials. doi:10.1002/adfm.202101633 |
Trashin, S., Morales Yánez, F. J., Thiruvottriyur Shanmugam,, S., Paredis, L., Carrion, E. N., Sariego, I., Muyldermans, S., Polman, K., Gorun, S. M., & De Wael, K. (2021). Nanobody-Based Immunosensor Detection Enhanced by Photocatalytic-Electrochemical Redox Cycling. Analytical Chemistry. doi:10.1021/acs.analchem.1c02876 |
Morales Yánez, F. J., Trashin, S., Sariego, I., Roucher, C., Paredis, L., Chico, M., De Wael, K., Muyldermans, S., Cooper, P., & Polman, K. (2020). Electrochemical detection of Toxocara canis excretory-secretory antigens in children from rural communities in Esmeraldas Province, Ecuador: association between active infection and high eosinophilia. Parasites and Vectors. doi:10.1186/s13071-020-04113-2 |
Morales Yánez, F. J. (2019). Development of innovative nanobody-based strategies to improve the diagnosis of human toxocariasis [Doctoral thesis, VUB - Vrije Universiteit Brussel]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/267254 |
Morales Yánez, F. J.* , Sariego, I.* , Vincke, C., Hassanzadeh-Ghassabeh, G., Polman, K., & Muyldermans, S. (2019). An innovative approach in the detection of Toxocara canis excretory/secretory antigens using specific nanobodies. International Journal for Parasitology. doi:10.1016/j.ijpara.2019.03.004 * These authors have contributed equally to this work. |
Morales Yánez, F. J., Trashin, S., Hermy, M., Sariego, I., Polman, K., Muyldermans, S., & De Wael, K. (2019). Fast One-Step Ultrasensitive Detection of Toxocara canis Antigens by a Nanobody-Based Electrochemical Magnetosensor. Analytical Chemistry. doi:10.1021/acs.analchem.9b01687 |
Morales Yánez, F. J., Trashin, S., Hermy, M., Sariego, I., De Wael, K., Polman, K., & Muyldermans, S. (2018). Ultrasensitive detection of toxocara canis excretory-secretory antigens by a nanobody electrochemical magnetosensor assay. Journal of the Americal Society of Tropical Medicine and Hygiene. |
Morales Yánez, F. J., Sariego, I., De Wael, K., Polman, K., Muyldermans, S., & Trashin, S. (2017). Development of a nanobody-based amperometric immunocapturing assay for sensitive and specific detection of Toxocara canis excretory-secretory antigen [Poster presentation]. 10th European Congress on Tropical Medicine and International Health. |
Romao, E., Morales Yánez, F. J., Hu, Y., Crauwels, M., De Pauw, P., Ghassanzadeh Hassanzadeh, G., Devoogdt, N., Ackaert, C., Vincke, C., & Muyldermans, S. (2016). Identification of Useful Nanobodies by Phage Display of Immune Single Domain Libraries Derived from Camelid Heavy Chain Antibodies. Current Pharmaceutical Design. doi:10.2174/1381612822666160923114417 |
Schousboe, M. L., Ranjitkar, S., Rajakaruna, R. S., Amerasinghe, P. H., Morales Yánez, F. J., Pearce, R., Ord, R., Leslie, T., Rowland, M., Gadalla, N., Konradsen, F., Bygbjerg, I. C., Roper, C., & Alifrangis, M. (2015). Multiple Origins of Mutations in the mdr1 Gene--A Putative Marker of Chloroquine Resistance in P. vivax. PLoS Neglected Tropical Diseases. doi:10.1371/journal.pntd.0004196 |
Morales Yánez, F. J., Sariego, I., Polman, K., & Muyldermans, S. (2015). Nanobody-based sandwich enzyme-linked immunosorbent assay for the detection of Toxocara canis excretory secretory proteins. Tropical Medicine and International Health. |
Schousboe, M. L., Ranjitkar, S., Rajakaruna, R. S., Amerasinghe, P. H., Konradsen, F., Morales Yanes, F. J., Ord, R., Rowland, M., Pearce, R., Leslie, T., Gadalla, N., Bygbjerg, I. C., Alifrangis, M., & Roper, C. (October 2014). Global and local genetic diversity at two microsatellite loci in Plasmodium vivax parasites from Asia, Africa and South America. Malaria Journal, 13, 392. doi:10.1186/1475-2875-13-392 |
Morales Yánez, F. J. (2013). CONTRIBUTIONS TO UNRAVELLING THE NATURE OF THE FALSE POSITIVITY IN CIRCUMSPOROZOITE Plasmodium falciparum ELISA [Master’s dissertation, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/267252 |
Morales Yánez, F. J. (2010). Estudios moleculares de Plasmodium falciparum y P. vivax en la Provincia de Sucumbios, Ecuador [Master’s dissertation, Universidad San Francisco de Quito]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/267253 |