Largeot, A., Klapp, V., Viry, E., Gonder, S., Fernandez Botana, I., Blomme, A., Benzarti, M., Pierson, S., Duculty, C., Marttila, P., Wierz, M., Gargiulo, E., Pagano, G., An, N., El Hachem, N., Perez Hermandez, D., Chakraborty, S., Ysebaert, L., François, J.-H., ... Moussay, E. (2023). Inhibition of MYC translation through targeting of the newly identified PHB-eIF4F complex as therapeutic strategy in CLL. Blood. doi:10.1182/blood.2022017839 |
Wathieu, C., Tielens, S., Lavergne, A., Shostak, K., Rolot, M., El Hachem, N., Xu, X., Close, P., Nguyen, L., Desmet, C., Dewals, B. G., & CHARIOT, A. (10 May 2022). A role for the tRNA-modifying enzyme Elp3 in tuft cell differentiation and in the immune response in the intestine [Paper presentation]. Type 2 Immunity in Early Life Symposium, Liège, Belgium. |
Habel, N.* , El Hachem, N.* , Soysouvanh, F.* , Hadhiri-Bzioueche, H., Giuliano, S., Nguyen, S., Horak, P., Gay, A.-S., Debayle, D., Nottet, N., Beranger, G., Bressac-de Paillerets, B., Bertolotto, C., & Ballotti, R. (2021). FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells. Cell Death and Differentiation. doi:10.1038/s41418-020-00710-x * These authors have contributed equally to this work. |
cheli, Y., tulic, M., El Hachem, N., nottet, N., Jacquel, A., Gesson, M., Strub, T., bille, K., picard-gauci, A., montaudié, H., beranger, G., passeron, T., Close, P., Bertolotto, C., & ballotti, R. (2021). ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity. Molecular Cancer. doi:10.1186/s12943-020-01306-2 |
Rapino, F.* , ZHOU, Z.* , RONCERO SANCHEZ, A. M.* , Joiret, M., Seca, C., El Hachem, N., Valenti, G., Latini, S., Shostak, K., Geris, L., Li, P., Huang, G., Mazzucchelli, G., Baiwir, D., Desmet, C., Chariot, A., Georges, M., & Close, P. (2021). Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate. Nature Communications, 12 (1), 2170. doi:10.1038/s41467-021-22254-5 * These authors have contributed equally to this work. |
Rosu, A., El Hachem, N., Rapino, F., Rouault-Pierre, K., Jorssen, J., SOMJA, J., Ramery, E., Thiry, M., Nguyen, L., Jacquemyn, M., Daelemans, D., Adams, C. M., Bonnet, D., Chariot, A., Close, P., Bureau, F., & Desmet, C. (2021). Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis. Journal of Experimental Medicine, 218 (3). doi:10.1084/jem.20200662 |
El Hachem, N., & Close, P. (September 2019). mRNA specific translation in resistant melanoma [Poster presentation]. Protein synthesis and translational control, Heidelberg, Germany. |
El Hachem, N., & Close, P. (September 2019). Defining the mechanisms of selective mRNA translation regulation during resistance [Paper presentation]. A bridge between the pathology and the physiology of the melanocyte, Brussels, Belgium. |
El Hachem, N., & Ballotti, R. (2018). Pro-tumoral function of HACE1. Oncoscience. |
El Hachem, N., & Ballotti, R. (2018). The pro-tumoral function of HACE1. Oncoscience. |
El Hachem, N., Habel, N., Naiken, T., Bzioueche, H., Cheli, Y., Beranger, G., Jaune, E., Rouaud, F., Nottet, N., Gaudel, C., Colosetti, P., Bertolotto, C., & Ballotti, R. (2018). Uncovering and deciphering the pro-invasive role of HACE1 in melanoma cells. Cell Death and Differentiation. doi:10.1038/s41418-018-0090-y |
Rouaud, F., Hamouda-Tekaya, N., Cerezo, M., Abbe, P., Zangari, J., Hofman, V., Ohanna, M., Baharia, M., El Hachem, N., Benfodda, Z., Lebeau, A., Tuli, M., Hofman, P., Bertolotto, C., Passeron, T., Annicotte, J.-S., Ballotti, R., & Rocchi, S. (2018). E2F1 inhibition mediates cell death of metastatic melanoma. Cell Death and Disease. doi:10.1038/s41419-018-0566-1 |
El Hachem, N. (2017). Rôle pro-tumorigénique de HACE1 dans le mélanome [Doctoral thesis, Université de Nice Sophia Antipolis]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/235464 |
El Hachem, N., & ballotti, R. (2017). Tumorigenic role of HACE1 in Melanoma [Paper presentation]. LABEX SIGNALIFE. |
El Hachem, N., & Ballotti, R. (2016). Regulation of fibronectin secretion by HACE1 [Poster presentation]. The Society for Melanoma Research (SMR). |
El Hachem, N., & Ballotti, R. (2015). Role of HACE1 protein in Melanoma development [Poster presentation]. LABEX SIGNALIFE. |
El Hachem, N., & Ballotti, R. (2015). Role of HACE1 in Melanoma [Poster presentation]. Annual doctoral school days. |
El Hachem, N., & Ballotti, R. (2015). Pro-tumorigenic role of HACE1 in Melanoma [Paper presentation]. Doctoral students and post-doctoral seminars. |
El Hachem, N., & Ballotti, R. (2015). Pro-tumorigenic role of HACE1 in Melanoma [Poster presentation]. From basic science to clinical application. |