Publications and communications of Arnaud Lavergne

Peiffer, R., Laverdeur, E., Gaigneaux, A., Boumahd, Y., Gullo, C., Rademaker, G., Crake, R., Lavergne, A., Maloujahmoum, N., Agirman, F., Herfs, M., Masamune, A., Letellier, E., Bellahcene, A., & Peulen, O. (2025). Targeting myoferlin in ER/Golgi vesicle trafficking reprograms pancreatic cancer-associated fibroblasts. EMBO Journal. doi:10.1038/s44318-025-00570-6

Dondajewska, E., Allepuz-Fuster, P., Maurizy, C., Hego, A., Ormenese, S., Lion, Q., Blomme, A., Close, P., Lavergne, A., Karim, L., Thiry, M., Nemazanyy, I., Krishnankutty, R., Marques, J., von Kriegsheim, A., Henneman, N. F., Panasyuk, G., Shostak, K., & Chariot, A. (August 2025). Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer. Advanced Science, 12 (31), 03022. doi:10.1002/advs.202503022

Adam, P., Salée, C., Quesada Calvo, F., Lavergne, A., Merli, A.-M., Massot, C., Bletard, N., Somja, J., Baiwir, D., Mazzucchelli, G., COIMBRA MARQUES, C., Delvenne, P., Louis, E., & Meuwis, M.-A. (31 July 2025). S100A14 as a Potential Biomarker of the Colorectal Serrated Neoplasia Pathway. International Journal of Molecular Sciences, 26 (15), 7401. doi:10.3390/ijms26157401

Galvan, B., Ongena, L., Bruyr, J., Fettweis, G., Lucarelli, E., Lavergne, A., Mariavelle, E., O'Grady, T. M., Hassoun, Z. E. O., Claes, M., Dubois, L., Lee, K. A. W., Kruys, V., Gueydan, C., Durand, J., Hervouet, E., Geyer, F. H., Banito, A., Imle, R., ... Dequiedt, F. (16 July 2025). Subversion of mRNA degradation pathways by EWSR1::FLI1 represents a therapeutic vulnerability in Ewing sarcoma. Nature Communications, 16 (1), 6537. doi:10.1038/s41467-025-61725-x

FUDVOYE, J., Lopez-Rodriguez, D., Glachet, C., Franssen, D., Terwagne, Q., Lavergne, A., Donneau, A.-F., Munaut, C., Dehan, P., Lomniczi, A., & Parent, A.-S. (March 2025). Developmental exposure to an environmentally relevant dose of Bisphenol S impairs postnatal growth and disrupts placental transcriptional profile in female rat. Reproductive Toxicology, 132, 108854. doi:10.1016/j.reprotox.2025.108854

Yang, B., Piedfort, O., Sanchez-Sanchez, G., Lavergne, A., Gong, M., Peng, G., Madrigal, A., Petrellis, G., Katsandegwaza, B., Rodriguez, L. R., Balthazar, A., Meyer, S. J., Van Isterdael, G., Van Duyse, J., Andris, F., Bai, Q., Marichal, T., Machiels, B., Nitschke, L., ... Dewals, B. G. (07 February 2025). IL-4 induces CD22 expression to restrain the effector program of virtual memory T cells. Science Immunology, 10 (104), 4841. doi:10.1126/sciimmunol.adk4841

Massoz, L., Bergemann, D., Lavergne, A., Reynders, C., Désiront, C., Goossens, C., Flasse, L., Peers, B., Voz, M., & Manfroid, I. (2024). Negative cell cycle regulation by Calcineurin is necessary for proper beta cell regeneration in zebrafish. eLife. doi:10.7554/elife.88813.1

Wathieu, C., Lavergne, A., Xu, X., Rolot, M., Nemazanyy, I., Shostak, K., El Hachem, N., Maurizy, C., Leemans, C., Close, P., Nguyen, L., Desmet, C., Tielens, S.* , Dewals, B. G.* , & Chariot, A.*. (2024). Loss of Elp3 blocks intestinal tuft cell differentiation via an mTORC1-Atf4 axis. EMBO Journal. doi:10.1038/s44318-024-00184-4

El Hachem, N., Leclercq, M., Susaeta Ruiz, M., Vanleyssem, R., Shostak, K., Körner, P.-R., Capron, C., Martin Morales, L., RONCARATI, P., Lavergne, A., Blomme, A., Turchetto, S., Goffin, E., Thandapani, P., Tarassov, I., Nguyen, L., Pirotte, B., Chariot, A., Marine, J.-C., ... Close, P. (2024). Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma. Nature Cell Biology. doi:10.1038/s41556-024-01439-2

Raman, R., Antony, M., Nivelle, R., Lavergne, A., Zappia, J., Guerrero Limon, G., Caetano da Silva, C., Kumari, P., Sojan, J. M., Degueldre, C., Bahri, M. A., Ostertag, A., Collet, C., Cohen-Solal, M., Plenevaux, A., Henrotin, Y., Renn, J., & Muller, M. (23 January 2024). The Osteoblast Transcriptome in Developing Zebrafish Reveals Key Roles for Extracellular Matrix Proteins Col10a1a and Fbln1 in Skeletal Development and Homeostasis. Biomolecules, 14 (2), 139. doi:10.3390/biom14020139

Dewals, B. G., Yang, B., Sanchez, G. S., Lavergne, A., Piedfort, O., Peng, G., Aguirre, A. M., Petrellis, G., Katsandegwaza, B., Isterdael, G. V., Duyse, J. V., Bai, Q., Marichal, T., Machiels, B., Nitschke, L., Najafabadi, H., King, I., & Vermijlen, D. (2023). IL-4 induces CD22 expression to restrain the effector program of self-reactive virtual memory T cells. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/304430. doi:10.21203/rs.3.rs-2747693/v1

Georges, A., Lavergne, A., Mandai, M., Lepiemme, F., Karim, L., Demeulenaere, L., Aguilar Ortmans, D., Schyns, M., Nguyen, L., Rakic, J.-M., Takahashi, M., Georges, M., & Takeda, H. (21 January 2023). Comparing the transcriptome of developing native and iPSC-derived mouse retinae by single cell RNA sequencing. Scientific Reports, 13 (1), 1223. doi:10.1038/s41598-023-28429-y

Franssen, D., Johansson, H. K. L., Lopez-Rodriguez, D., Lavergne, A., Terwagne, Q., Boberg, J., Christiansen, S., Svingen, T., & Parent, A.-S. (2023). Perinatal exposure to the fungicide ketoconazole alters hypothalamic control of puberty in female rats. Frontiers in Endocrinology, 14, 1140886. doi:10.3389/fendo.2023.1140886

Reuter, A.-S., Stern, D., Bernard, A., Goossens, C., Lavergne, A., Flasse, L., Von Berg, V., Manfroid, I., Peers, B., & Voz, M. (14 March 2022). Identification of an evolutionarily conserved domain in Neurod1 favouring enteroendocrine versus goblet cell fate. PLoS Genetics, 18 (3), 1010109. doi:10.1371/journal.pgen.1010109

Carril Pardo, C. A., Massoz, L., Dupont, M., Bergemann, D., Bourdouxhe, J., Lavergne, A., Tarifeño Saldivia, E., Helker, C. S., Stainier, D. Y. T., Peers, B., Voz, M., & Manfroid, I. (2022). A δ-cell subpopulation with pro-β cell identity contributes to efficient age-independent recovery in a zebrafish diabetes model. eLife, 11. doi:10.7554/eLife.67576

Payen, V. L.* , Lavergne, A.* , Alevra Sarika, N., Colonval, M., Karim, L., Deckers, M., Najimi, M., Coppieters, W., CHARLOTEAUX, B., Sokal, E. M., & El Taghdouini, A. (21 March 2021). Single-cell RNA sequencing of human liver reveals hepatic stellate cell heterogeneity. JHEP Reports: Innovation in Hepatology, 3 (3), 100278. doi:10.1016/j.jhepr.2021.100278

Jacques, S., Arjomand, A., Perée, H., COLLINS, P., Mayer, A., Lavergne, A., Wéry, M., Mni, M., Hego, A., Thuillier, V., Becker, G., Bahri, M. A., Plenevaux, A., Di Valentin, E., Oury, C., MOUTSCHEN, M., Delvenne, P., Paquot, N., & Rahmouni, S. (2021). Dual‑specificity phosphatase 3 deletion promotes obesity, non‑alcoholic steatohepatitis and hepatocellular carcinoma. Scientific Reports, 11, 5817. doi:10.1038/s41598-021-85089-6

Lavergne, A. (2020). Transcriptomic landscape of pancreatic cell types and the identification of a common Pax6 - dependent gene regulatory network in pancreatic and intestinal endocrine cells [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/250749

GEORGES, A., Lavergne, A., Mandai, M., Lepiemme, F., Karim, L., Demeulenaere, L., Aguilar Ortmans, D., Schyns, M., Nguyen, L., RAKIC, J.-M., Takahashi, M., Georges, M., & Takeda, H. (2020). Combined analysis of single cell RNA-Seq and ATAC-Seq data reveals putative regulatory toggles operating in native and iPS-derived retina. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/292544. doi:10.1101/2020.03.02.972497

Lavergne, A.* , Tarifeño-Saldivia, E.* , Pirson, J., Reuter, A.-S., Flasse, L., Manfroid, I., Voz, M.* , & Peers, B.*. (2020). Pancreatic and intestinal endocrine cells in zebrafish share common transcriptomic signatures and regulatory programmes. BMC Biology, 18 (1), 109. doi:10.1186/s12915-020-00840-1

Tarifeño Saldivia, E., Lavergne, A., Bernard, A., Padamata, K., Bergemann, D., Voz, M., Manfroid, I., & Peers, B. (21 March 2017). Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes. BMC Biology, 15. doi:10.1186/s12915-017-0362-x