Coelho Cristino Mamede, L. C., Fall, F., Schoumacher, M., Ledoux, A., Bugli, C., De Tullio, P., Quetin-Leclercq, J., Govaerts, B., & Frederich, M. (February 2024). Comparison of extraction methods in vitro Plasmodium falciparum: A 1 H NMR and LC-MS joined approach. Biochemical and Biophysical Research Communications, 703, 149684. doi:10.1016/j.bbrc.2024.149684 |
Koopmans, S. J., Binnendijk, G., Ledoux, A., Choi, Y. H., Mes, J. J., Guan, X., Molist, F., Thị Minh, T. P., & van der Wielen, N. (2024). Momordica charantia fruit reduces plasma fructosamine whereas stems and leaves increase plasma insulin in adult mildly diabetic obese Göttingen Minipigs. PLoS ONE, 19 (3), 0298163. doi:10.1371/journal.pone.0298163 |
Le Loarer, A., Dufossé, L., Bign, J., Frederich, M., Ledoux, A., Fouillaud, M., Gauvin-Bialecki, A., Coppola, D., Sala, G., & Khalil, Z. (28 December 2023). OSMAC Method to Assess Impact of Culture Parameters on Metabolomic Diversity and Biological Activity of Marine-Derived Actinobacteria. Marine Drugs, 22 (1), 23. doi:10.3390/md22010023 |
Leka, K., Hoste, A., Xin, R., Hamann, C., Garigliany, M.-M., & Ledoux, A. (06 July 2023). Exploring the potential of traditional Chinese medicines for antiviral therapy [Poster presentation]. 71st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Dublin, Ireland. |
Ledoux, A., Leka, K., Jansen, O., Bonnet, O., Hamann, C., Angenot, L., Garigliany, M.-M., & Frederich, M. (July 2023). Exploring the antiviral activity of flavonoids from Strychnos variabilis leaves against SARS-CoV-2. Planta Medica, 89 (14), 1421. |
Lahngong, M. S., Loe, G. E., Jansen, O., Coelho Cristino Mamede, L. C., Ledoux, A., Noukimi, S. F., Abenwie, S. N., Ghogomu, S. M., Souopgui, J., Robert, A., Demeyer, K., & Frederich, M. (29 April 2023). Secondary Metabolites Isolated from Artemisia afra and Artemisia annua and Their Anti-Malarial, Anti-Inflammatory and Immunomodulating Properties—Pharmacokinetics and Pharmacodynamics: A Review. Metabolites, 13 (5), 613. doi:10.3390/metabo13050613 |
Gerometta, E., Herbette, G., Garayev, E., Marvilliers, A., Naubron, J.-V., Di Giorgio, C., Campos, P.-E., Clerc, P., Ledoux, A., Frederich, M., Baghdikian, B., Grondin, I., & Gauvin-Bialecki, A. (23 April 2023). Cytotoxic Metabolites from Calophyllum tacamahaca Willd.: Isolation and Detection through Feature-Based Molecular Networking. Metabolites, 13 (5), 582. doi:10.3390/metabo13050582 |
Le Loar, A., Marcellin-Gros, R., Dufossé, L., Bignon, J., Frederich, M., Ledoux, A., Ferreira Queiroz, E., Wolfender, J.-L., Gauvin-Bialecki, A., & Fouillaud, M. (27 February 2023). Prioritization of Microorganisms Isolated from the Indian Ocean Sponge Scopalina hapalia Based on Metabolomic Diversity and Biological Activity for the Discovery of Natural Products. Microorganisms, 11 (3), 697. doi:10.3390/microorganisms11030697 |
Ledoux, A., Hamann, C., Bonnet, O., Jullien, K., Quetin-Leclercq, J., Tchinda, A., Smadja, J., Gauvin-Bialecki, A., Maquoi, E., & Frederich, M. (25 January 2023). Bioactive Clerodane Diterpenoids from the Leaves of Casearia coriacea Vent. Molecules, 28 (3), 1197. doi:10.3390/molecules28031197 |
Coelho Cristino Mamede, L. C., Fall, F., Schoumacher, M., Ledoux, A., De Tullio, P., Quetin-Leclercq, J., & Frederich, M. (2022). Recent metabolomic developments for antimalarial drug discovery. Parasitology Research. doi:10.1007/s00436-022-07673-7 |
Bonnet, O., Beniddir, M. A., Champy, P., Degotte, G., Coelho Cristino Mamede, L. C., Desdemoustier, P., Ledoux, A., Tchinda, A. T., Angenot, L., & Frederich, M. (26 September 2022). Unveiling antiplasmodial alkaloids from a cumulative collection of Strychnos extracts by multi-informative molecular networks. Frontiers in Molecular Biosciences, 9. doi:10.3389/fmolb.2022.967012 |
Leka, K., Ledoux, A., Desdemoustier, P., Garigliany, M.-M., & Frederich, M. (29 August 2022). TRADITIONAL CHINESE MEDICINE: A PATH WORTH EXPLORING IN THE FIGHT AGAINST COVID-19? [Poster presentation]. 70th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Thessaloniki, Greece. |
Mbombo Mungitshi, P., Frederich, M., Ledoux, A., Mutwale Kapepula, P., Ngombe Kabamba, N., & Tiabou Tchinda, A. (2022). ETUDE PHYTOCHIMIQUE ET EVALUATION DE L'ACTIVITE ANTIPLASMODIALE DE PSEUDOLACHNOSTYLIS MAPROUNEIFOLIA PAX (EUPHORBIACEAE). |
Bonnet, O., Beniddir, M. A., Champy, P., Kagisha, V., Nyirimigabo, A., Hamann, C., Jgerenaia, G., Ledoux, A., Tiabou Tchinda, A., Angenot, L., & Frederich, M. (09 June 2022). Exploration by molecular networking of Strychnos alkaloids reveals the unexpected occurrence of strychnine in seven Strychnos species. Toxicon, 215, 57-68. doi:10.1016/j.toxicon.2022.06.002 |
Leka, K., Hamann, C., Desdemoustier, P., Frederich, M., Garigliany, M.-M., & Ledoux, A. (2022). In vitro antiviral activity against SARS-CoV-2 of common herbal medicinal extracts and their bioactive compounds. Phytotherapy Research. doi:10.1002/ptr.7463 |
Fall, F., Coelho Cristino Mamede, L. C., Schioppa, L., Ledoux, A., De Tullio, P., Michels, P., Frederich, M., & Quetin-Leclercq, J. (19 March 2022). Trypanosoma brucei: Metabolomics for analysis of cellular metabolism and drug discovery. Metabolomics, 18 (4), 20. doi:10.1007/s11306-022-01880-0 |
Coelho Cristino Mamede, L. C., Schoumacher, M., Cirillo, A., Fall, F., Bugli, C., Ledoux, A., De Tullio, P., Quetin-Leclercq, J., Govaerts, B., & Frederich, M. (02 February 2022). Exploration of untargeted metabolomic extraction methods of in vitro malaria samples by 1H NMR analysis - follow up [Poster presentation]. CIRM Day, Liège, Belgium. |
Coelho Cristino Mamede, L. C., Schoumacher, M., Cirillo, A., Fall, F., Bugli, C., Ledoux, A., De Tullio, P., Quetin-Leclercq, J., Govaerts, B., & Frederich, M. (November 2021). Exploration of untargeted metabolomic extraction methods for in vitro malaria samples by 1H NMR analysis [Poster presentation]. 14èmes Journées Scientifiques du Réseau Francophone de Métabolomique et Fluxomique, Aussois, France. |
Nea, F., Bitchi, B. M., Genva, M., Ledoux, A., Tchinda Tiabou, A., Frederich, M., Tonzibo, Z. F., & Fauconnier, M.-L. (15 January 2021). Phytochemical investigation and biological activities from Lantana rhodesiensis Moldenke [Poster presentation]. Les Journées Jeunes Chercheurs Condorcet - J2C2. |
Kagisha, V., Marini Djang'Eing'A, R., Muganga, R., Bonnet, O., Tchinda, A. T., Jansen, O., Tomani, J. C., Ranarivelo, N., Ledoux, A., Nyirimigabo, A., & Frederich, M. (2021). Pentas longiflora Oliv. (Rubiaceae), a plant used in the treatment of Pityriasis Versicolor in Rwanda: Chemical composition and standardization of leaves and roots. Fitoterapia, 153, 104974. doi:10.1016/j.fitote.2021.104974 |
Nea, F., Bitchi, M. B., Genva, M., Ledoux, A., Tchinda Tiabou, A., Damblon, C., Frederich, M., Tonzibo, Z. F., & Fauconnier, M.-L. (2021). Phytochemical investigation and biological activities of Lantana rhodesiensis. Molecules, 26 (4), 846. doi:10.3390/molecules26040846 |
Ledoux, A., Coelho Cristino Mamede, L. C., Palazzo, C., Furst, T., Jansen, O., De Tullio, P., Kagisha, V., Pendeville-Samain, H., Fillet, M., Piel, G., & Frederich, M. (18 May 2020). Heparin-Coated Liposomes Improve Antiplasmodial Activity and Reduce the Toxicity of Poupartone B. Planta Medica International Open, 7 (e), 73–80. doi:10.1055/a-1158-0569 |
Tanoh, A. E., Boue, G. B. (Other coll.), Nea, F. (Other coll.), Martin, H. (Other coll.), Genva, M. (Other coll.), Ledoux, A. (Other coll.), Tonzibo, Z. F. (Other coll.), & Fauconnier, M.-L. (Other coll.). (31 January 2020). Seasonal effect on the chemical composition of essential oils hydrodistillated from Zanthoxylum leprieurii Guill. & Perr. and on their biological activities [Paper presentation]. 25th National Symposium for Applied Biological Sciences (NSABS), Gembloux, Belgium. |
Coelho Cristino Mamede, L. C., Ledoux, A., Jansen, O., & Frederich, M. (2020). Natural Phenolic Compounds and Derivatives as Potential Antimalarial Agents. Planta Medica, 86 (9), 585-618. doi:10.1055/a-1148-9000 |
Tanoh, A. E., Blanchard Boué, G., Nea, F., Genva, M., Wognin, E. L., Ledoux, A., Martin, H., Tonzibo, Z. F., Frederich, M., & Fauconnier, M.-L. (2020). Seasonal effect on the chemical composition, insecticidal properties and other biological activities of Zanthoxylum leprieurii Guill. & Perr. essential oils. Foods, 9 (5), 550. doi:10.3390/foods9050550 |
Tomani, J. C. D., Kagisha, V., Tchinda, A. T., Jansen, O., Ledoux, A., Vanhamme, L., Frederich, M., Muganga, R., & Souopgui, J. (2020). The Inhibition of NLRP3 Inflammasome and IL-6 Production by Hibiscus noldeae Baker f. Derived Constituents Provides a Link to Its Anti-Inflammatory Therapeutic Potentials. Molecules, 25 (20), 4693. doi:10.3390/molecules25204693 |
Ledoux, A. (2019). Étude des potentialités antiplasmodiales de plantes endémiques des Mascareignes: Poupartia borbonica Gmel., une nouvelle source de composés antimalariques prometteurs ? [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/234062 |
Ielciu, I., Frederich, M., Hanganu, D., Angenot, L., Olah, N.-K., Ledoux, A., Crișan, G., & Păltinean, R. (2019). Flavonoid Analysis and Antioxidant Activities of the Bryonia alba L. Aerial Parts. Antioxidants, 8 (4 108). doi:10.3390/antiox8040108 |
Degotte, G., Halleux, A., Hans, A., Jansen, O., Ledoux, A., Desdemoustier, P., Pirotte, B., Francotte, P., & Frederich, M. (December 2018). Preparation of ellagic acid derivatives through a total synthesis approach to improve bioavailability [Poster presentation]. 1st CIRM Day, Liège, Belgium. |
Degotte, G., Francotte, P., Frederich, M., Halleux, A., Hans, A., Jansen, O., Ledoux, A., Desdemoustier, P., & Pirotte, B. (November 2018). Pharmacomodulation of ellagic acid, a promising antiplasmodial agent, to improve its bioavailability [Poster presentation]. 30th International Symposium on the Chemistry of Natural Products and the 10th International Conference on Biodiversity, Athens, Greece. |
Mskhiladze, L., Chincharadze, D., St-Gelais, A., Mshvildadze, V., Pichette, A., Ledoux, A., Tits, M., & Frederich, M. (July 2016). Isolation and Identification of Steroid and Flavonoid Glycosides from the Flowers of Allium gramineum. International Journal of Pharmaceutical Sciences and Drug Research, 8 (4), 240-243. |
Ledoux, A., Mareatefau, H., Jansen, O., Etienne, D., quetin-Leclercq, J., Clerc, P., Smadja, J., & Frederich, M. (April 2015). Phytochemical Profile and Biological Activity Evaluation of Zanthoxylum heterophyllum Leaves against Malaria. Planta Medica Letters, 2, 10-e11. |