Publications and communications of Grégory Fettweis

Fettweis, G., Johnson, T., Almeida-Prieto, B., Weller-Pérez, J., Presman, D., Hager, G., & Alvarez De La Rosa, D. (2024). The mineralocorticoid receptor forms higher order oligomers upon DNA binding. Protein Science: A Publication of the Protein Society. doi:10.1002/pro.4890©

Fettweis, G., Johnson, T. A., Almeida-Prieto, B., Presman, D. M., Hager, G. L., & de la Rosa, D. A. (2023). The mineralocorticoid receptor forms higher order oligomers upon DNA binding. bioRxiv : the preprint server for biology. doi:10.1101/2023.01.26.525752

Johnson, T. A., Fettweis, G., Wagh, K., Almeida-Prieto, B., Hager, G. L., & de la Rosa, D. A. (2023). The Glucocorticoid Receptor is Required for Efficient Aldosterone-Induced Transcription by the Mineralocorticoid Receptor. bioRxiv : the preprint server for biology. doi:10.1101/2023.01.26.525745

Jiménez-Panizo, A., Alegre-Martí, A., Tettey, T. T., Fettweis, G., Abella, M., Antón, R., Johnson, T. A., Kim, S., Schiltz, R. L., Núñez-Barrios, I., Font-Díaz, J., Caelles, C., Valledor, A. F., Pérez, P., Rojas, A. M., Fernández-Recio, J., Presman, D. M., Hager, G. L., Fuentes-Prior, P., & Estébanez-Perpiñá, E. (09 December 2022). The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities. Nucleic Acids Research, 50 (22), 13063 - 13082. doi:10.1093/nar/gkac1119

Wagh, K., Stavreva, D. A., Jensen, R. A., Paakinaho, V., Fettweis, G., Schiltz, R. L., Wüstner, D., Mandrup, S., Presman, D. M., Upadhyaya, A., & Hager, G. L. (2022). Single-molecule tracking reveals two low-mobility states for chromatin and transcriptional regulators within the nucleus. Science Advances. doi:10.1101/2022.07.25.501476

Rinaldi, L.* , Fettweis, G.* , Kim, S., Garcia, D. A., Fujiwara, S., Johnson, T. A., Tettey, T. T., Ozbun, L., Pegoraro, G., Puglia, M., Blagoev, B., Upadhyaya, A., Stavreva, D. A., & Hager, G. L. (April 2022). The glucocorticoid receptor associates with the cohesin loader NIPBL to promote long-range gene regulation. Science Advances, 8 (13), 8360. doi:10.1126/sciadv.abj8360
* These authors have contributed equally to this work.

Fettweis, G. (2022). The glucocorticoid receptor associates with the cohesin loader NIPBL to promote long-range gene regulation [Poster presentation]. Precision Medicine Forum, Brussels, Belgium.

Fettweis, G. (2022). Cohesin Complex implication in Transcription Factor-mediated chromatin looping and gene regulation [Paper presentation]. GIGA-Medical Genomic meeting, Liège, Belgium.

Fettweis, G. (2022). Cohesin Complex implication in Transcription Factor-mediated chromatin looping and gene regulation [Paper presentation]. IBMM meeting, ULB.

Garcia, D. A.* , Fettweis, G.* , Presman, D. M.* , Paakinaho, V., Jarzynski, C., Upadhyaya, A., & Hager, G. L. (09 July 2021). Power-law behavior of transcription factor dynamics at the single-molecule level implies a continuum affinity model. Nucleic Acids Research, 49 (12), 6605 - 6620. doi:10.1093/nar/gkab072
* These authors have contributed equally to this work.

Garcia, D. A., Johnson, T. A., Presman, D. M., Fettweis, G., Wagh, K., Rinaldi, L., Stavreva, D. A., Paakinaho, V., Jensen, R. A. M., Mandrup, S., Upadhyaya, A., & Hager, G. L. (01 April 2021). An intrinsically disordered region-mediated confinement state contributes to the dynamics and function of transcription factors. Molecular Cell, 81 (7), 1484 - 1498.e6. doi:10.1016/j.molcel.2021.01.013

Fettweis, G. (2021). Quantitative light microscopy and genomics synergize in the exploration of transcriptional regulation [Paper presentation]. Veterinary School general meeting, University of Glasgow, Glasgow, United Kingdom.

Fettweis, G. (2021). Quantitative light microscopy and genomics synergize in the exploration of transcriptional regulation [Paper presentation]. Institut DeDuve meeting, UCL.

Fettweis, G. (2020). Quantitative Microscopy and Genomic: a power mix to unveil gene regulation mechanisms [Paper presentation]. GIGA-R meeting, Liège, Belgium.

Fettweis, G. (2020). Mechanistic characterization of promoter/enhancer progression for glucocorticoid receptor responsive genes [Poster presentation]. Chromatin and Epigenetics, Heidelberg, Germany.

Stavreva, D. A., Garcia, D. A., Fettweis, G., Gudla, P. R., Zaki, G. F., Soni, V., McGowan, A., Williams, G., Huynh, A., Palangat, M., Schiltz, R. L., Johnson, T. A., Presman, D. M., Ferguson, M. L., Pegoraro, G., Upadhyaya, A., & Hager, G. L. (19 September 2019). Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility. Molecular Cell, 75 (6), 1161 - 1177.e11. doi:10.1016/j.molcel.2019.06.042

Fettweis, G. (2019). Toward A Mechanistic Characterization of Promoter Progression for Glucocorticoid Receptor Responsive Genes [Poster presentation]. NCI Symposium on Chromosome Biology, Bethesda, United States.

Fettweis, G. (2019). Toward A Mechanistic Characterization of Promoter Progression for Glucocorticoid Receptor Responsive Genes [Poster presentation]. ASCB-EMBO meeting, United States.

Fettweis, G. (2018). Power-law behavior of Transcription Factors dynamic [Poster presentation]. Single-Biomolecules, Cold Spring Harbor, United States.

Fettweis, G., Di Valentin, E., L'homme, L., Lassence, C., Dequiedt, F., Fillet, M., Coupienne, I., & Piette, J. (2017). RIP3 antagonizes a TSC2-mediated pro-survival pathway in glioblastoma cell death. Biochimica et Biophysica Acta. doi:10.1016/j.bbamcr.2016.10.014

Fettweis, G. (2016). Cell death signaling in cancer cells treated by Photodynamic Therapy [Doctoral thesis, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/201102

Marcélis, L., Kajouj, S., Ghesquière, J., Fettweis, G., Coupienne, I., Lartia, R., Surin, M., Defrancq, E., Piette, J., Moucheron, C., & Kirsch-De Mesmaeker, A. (June 2016). Highly DNA-Photoreactive Ruthenium 1,4,5,8-Tetraazaphenanthrene Complex Conjugated to the TAT Peptide: Efficient Vectorization inside HeLa Cells without Phototoxicity – The Importance of Cellular Distribution. European Journal of Inorganic Chemistry, 2016 (18), 2902 - 2911. doi:10.1002/ejic.201600278

Fettweis, G., Coupienne, I., Fillet, M., Lassence, C., Di Valentin, E., & Piette, J. (October 2014). TSC2 and 14-3-3 proteins down-regulate a RIP3 dependent PDT-induced Necroptosis in Glioblastoma [Poster presentation]. Keystone Symposia : "Cell death Signaling in Cancer and the Immune System".

Fettweis, G., Coupienne, I., Fillet, M., & Piette, J. (04 September 2013). Role of RIP3 in PDT-induced glioblastoma Cell Death [Poster presentation]. 15th Congress of the European Society for Photobiology, Liège, Belgium.

Coupienne, I., Fettweis, G., & Piette, J. (10 December 2012). Characterization of chemotherapy-induced cell death in glioblastoma [Poster presentation]. Séminaire des chercheurs Télévie 2013, Liège, Belgium.

Coupienne, I., Fettweis, G., & Piette, J. (27 January 2012). 5-ALA-PDT induces RIP3-dependent necrosis in glioblastoma [Poster presentation]. Cell Death in Cancer (EACR meeting), Amsterdam, Netherlands.

Fettweis, G. (2011). Rôle de RIPK3 dans la mort induite par la thérapie photodynamique [Master’s dissertation, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/99997

Coupienne, I.* , Fettweis, G.* , & Piette, J. (September 2011). RIP3 Expression Induces a Death Profile Change in U2OS Osteosarcoma Cells After 5-ALA-PDT. Lasers in Surgery and Medicine, 43 (7), 557–564. doi:10.1002/lsm.21088
* These authors have contributed equally to this work.

Coupienne, I., Fettweis, G., & Piette, J. (January 2011). Study of the combined effect of 5-ALA-based photodynamic therapy and NF-kappaB inhibition on human glioblastoma cell survival [Poster presentation]. Cell Signal-omics 2011 Integrated cellular pathology Systems biology of human disease, Luxembourg, Luxembourg.

Coupienne, I., Fettweis, G., Rubio-Romero, N., Agostinis, P., & Piette, J. (2011). 5-ALA-PDT induces RIP3-dependent necrosis in glioblastoma. Photochemical and Photobiological Sciences. doi:10.1039/c1pp05213f