Publications and communications of Virginie Neirinckx

Lombard, A.* , Isci, D.* , Reuter, G., Di Valentin, E., Hego, A., Martin, D., Rogister, B., & Neirinckx, V. (In press). Development of an intraventricular Adeno-Associated Virus-based labelling strategy for glioblastoma cells nested in the subventricular zone. Neuro-Oncology Advances. Neuro-Oncology Advances.
* These authors have contributed equally to this work.

D'Uonnolo, G.* , Isci, D.* , Nosirov, B., Kuppens, A., Wantz, M., Nazarov, P., Golebiewska, A., Rogister, B., Chevigné, A.* , Neirinckx, V.* , & Szpakowska, M.*. (November 2024). Patient-based multilevel transcriptome exploration highlights relevant chemokines and chemokine receptor axes in glioblastoma. Computers in Biology and Medicine, 182, 109197. doi:10.1016/j.compbiomed.2024.109197
* These authors have contributed equally to this work.

Waked, A., Crabbé, M., Neirinckx, V., Rogister, B., Benotmane, M. A., & Vermeulen, K. (26 April 2024). Preclinical evaluation of 177Lu-radiolabelled CXCR4-targeting peptides for glioblastoma therapy [Poster presentation]. 9th Symposium on Medical Radioisotopes (ISMERAD) | Alpha Therapy: New approaches in radionuclide therapy, Ghent, Belgium.

Isci, D., Kuppens, A., Scalisi, J., COKAIKO, J., Wantz, M., Szpakowska, M., Chevigné, A., Rogister, B., & Neirinckx, V. (2024). Heterogeneous expression of the atypical chemokine receptor ACKR3 in glioblastoma patient-derived tissue samples and cell cultures. Scientific Reports, 14, 21925. doi:10.1038/s41598-024-73064-w

Waked, A., Crabbé, M., Neirinckx, V., Rodriguez Pérez, S., Wellens, J., Rogister, B., Benotmane, A., & Vermeulen, K. (2024). Preclinical evaluation of CXCR4 peptides for targeted radionuclide therapy in glioblastoma. EJNMMI Radiopharmacy and Chemistry. doi:10.1186/s41181-024-00282-y

Simonet, A., Isci, D., Neirinckx, V., Jerusalem, G., & Rogister, B. (06 December 2023). 190P Immune-related roles of B7H3 in glioblastoma [Poster presentation]. ESMO Immuno-oncology. doi:10.1016/j.iotech.2023.100649

Da Veiga, M.-A., Coppieters't Wallant, N., Lombard, A., Rogister, B., Neirinckx, V.* , & Piette, C.*. (16 June 2023). Comprehensive profiling of stem-like features in pediatric glioma cell cultures and their relation to the subventricular zone. Acta Neuropathologica Communications, 11 (1), 96. doi:10.1186/s40478-023-01586-x
* These authors have contributed equally to this work.

Coppieters, N., Scalisi, J., Di Gregorio, M., Leparc, L., Velazquez Saez, L., Lombard, A., Rogister, B., & Neirinckx, V. (2023). Study of Strawberry Notch homolog 1 and 2 expression in human glioblastoma. Journal of Neuro-Oncology. doi:10.1007/s11060-023-04240-7

Dosquet, H., Neirinckx, V., Meyrath, M., Wantz, M., Haan, S., Niclou, S. P., Szpakowska, M., & Chevigné, A. (2023). Nanoluciferase-based complementation assays to monitor activation, modulation and signaling of receptor tyrosine kinases (RTKs). Methods in Enzymology, 682, 1 - 16. doi:10.1016/bs.mie.2022.09.002

Sanchez Gil, J., Dubois, M., Neirinckx, V., LOMBARD, A., Coppieters't Wallant, N., D'arrigo, P., Isci, D., Aldenhoff, T., Brouwers, B., Lassence, C., ROGISTER, B., Lebrun, M., & Sadzot, C. (2022). Nanobody-based retargeting of an oncolytic herpesvirus for eliminating CXCR4+ GBM cells: a proof-of-principle. Molecular Therapy: Oncolytics. doi:10.1016/j.omto.2022.06.002

Da Veiga, M.-A., Rogister, B., LOMBARD, A., Neirinckx, V.* , & PIETTE, C.*. (04 May 2022). Glioma Stem Cells in Pediatric High-Grade Gliomas: From Current Knowledge to Future Perspectives. Cancers, 14 (9), 2296. doi:10.3390/cancers14092296
* These authors have contributed equally to this work.

Isci, D., Veiga, D., Cokaiko, J., LOMBARD, A., Chevigné, A., ROGISTER, B., & Neirinckx, V. (10 April 2022). Study of the ACKR3/CXCR7 receptor in glioblastoma [Poster presentation]. Télévie Seminar, Liège, Belgium.

Bartholomé, O., Neirinckx, V., & Rogister, B. (2022). SV2A absence in GABAergic neurons induces seizure in a conditional KO model [Poster presentation]. FENS 2022, Paris, France.

Isci, D.* , D'Uonnolo, G.* , Wantz, M., Rogister, B., LOMBARD, A., Chevigné, A., Szpakowska, M., & Neirinckx, V. (28 December 2021). Patient-Oriented Perspective on Chemokine Receptor Expression and Function in Glioma. Cancers, 14 (1), 130. doi:10.3390/cancers14010130
* These authors have contributed equally to this work.

Sanchez Gil, J., D'arrigo, P., Neirinckx, V., Isci, D., Brouwers, B., LOMBARD, A., Rogister, B., Lebrun, M., & Sadzot, C. (2021). Targeting of CXCR4+ Glioblastoma initiating cells with a retargeted Oncolytic Herpesvirus (oHSV): proof of concept [Paper presentation]. IHW2021: 45th International Herpesvirus Workshop.

Wislet-Gendebien, S., Poulet, C., Neirinckx, V., Hennuy, B., Swingland, J. T., Laudet, E., Sommer, L., Shakova, O., Bours, V., & Rogister, B. (2021). Correction: In Vivo Tumorigenesis Was Observed after Injection of In Vitro Expanded Neural Crest Stem Cells Isolated from Adult Bone Marrow. PLoS ONE, 16 (9), 0256477. doi:10.1371/journal.pone.0256477

Schuster, A., Klein, E., Neirinckx, V., Moldrup Knudsen, A., Fabian, C., Hau, A.-C., Dieterle, M., Nazarov, P., Golebiewska, A., Muller, A., Perez Hernandez, D., Rodius, S., Dittmar, G., Bjerkvig, R., Herold-Mende, C., Klink, B., Winther Christensen, B., & Niclou, S. (11 December 2020). AN1-type zinc finger protein 3 (ZFAND3) is a transcriptional regulator that drives Glioblastoma invasion. Nature Communications, 11 (1), 6366. doi:10.1038/s41467-020-20029-y

Golebiewska, A., Hau, A.-C., Oudin, A., Stieber, D., Yabo, Y., Baus, V., Barthélémy, V., Klein, E., Bougnaud, S., Keunen, O., Wantz, M., Michelucci, A., Neirinckx, V., Muller, A., Kaoma, T., Nazarov, P., Azuaje, F., De Falco, A., Flies, B., ... Niclou, S. (December 2020). Primary and recurrent glioma patient-derived orthotopic xenografts (PDOX) represent relevant patient avatars for precision medicine. Acta Neuropathologica, 140 (6), 919-949. doi:10.1007/s00401-020-02226-7

Bartholomé, O., Van den ackerveken, P., de la Brassinne, O., Neirinckx, V., & Rogister, B. (11 July 2020). Only GABAergic neurons induced seizures following SV2A recombination [Poster presentation]. Federation of European Neuroscience Societies (FENS).

Bartholomé, O., de la Brassinne Bonardeaux, O., Neirinckx, V., & Rogister, B. (2020). A Composite Sketch of Fast-spiking Parvalbumin-positive Neurons. Cerebral Cortex Communications. doi:10.1093/texcom/tgaa026

Neirinckx, V., Hau, A.-C., Schuster, A., Fritah, S., Chevigné, A., Schmidt, M. H. H., & Niclou, S. P. (September 2019). Pan-RTK inhibition of sLRIG1 mediates AXL downregulation in Glioblastoma. Neuro-Oncology, 21 (Supp 3). doi:10.1093/neuonc/noz126.155

Neirinckx, V., Hau, A.-C., Schuster, A., Fritah, S., Tiemann, K., Klein, E., Nazarov, P. V., Matagne, A., Szpakowska, M., Meyrath, M. M. R., Chevigné, A., Schmidt, M. H. H., & Niclou, S. P. (September 2019). The soluble form of pan-RTK inhibitor and tumor suppressor LRIG1 mediates downregulation of AXL through direct protein–protein interaction in glioblastoma. Neuro-Oncology Advances, 1 (1). doi:10.1093/noajnl/vdz024

Neirinckx, V., Schuster, A., Chevigné, A., Schmidt, M. H. H., & Niclou, S. (September 2018). Harnessing soluble LRIG1 for pan-RTK targeting in glioblastoma. Neuro-Oncology, 20 (Supp 3). doi:10.1093/neuonc/noy139.011

Neirinckx, V., Hedman, H., & Niclou, S. P. (August 2017). Harnessing LRIG1-mediated Inhibition of Receptor Tyrosine Kinases for Cancer Therapy. Biochimica et Biophysica Acta. Reviews on Cancer, 1868 (1), 109-116. doi:10.1016/j.bbcan.2017.02.007

Coste, C., Neirinckx, V., Sharma, A., Agirman, G., Rogister, B., FOGUENNE, J., Lallemend, F., Gothot, A., & Wislet, S. (2017). Human bone marrow harbors cells with neural crest-associated characteristics like human adipose and dermis tissues. PLoS ONE, 12 (7), 0177962. doi:10.1371/journal.pone.0177962

Coste, C., Neirinckx, V., Rogister, B., Gothot, A., & Wislet, S. (25 January 2016). Human Adult Bone Marrow and Adipose Tissue Harbor Stem Cells with Neural Crest Characteriscs [Poster presentation]. GIGA Day, Liège, Belgium.

Lombard, T., Neirinckx, V., Rogister, B., Gilon, Y., & Wislet, S. (2016). Medication-Related Osteonecrosis of the Jaw: New Insights into Molecular Mechanisms and Cellular Therapeutic Approaches. Stem Cells International. doi:10.1155/2016/8768162

MENTEN, C.* , Serrano Navacerrada, M. E.* , Bartholomé, O., Gil, J. S., Neirinckx, V., Wislet, S., Becker, G., Plenevaux, A., Van Den Ackerveken, P.* , & Rogister, B.*. (2016). Development and validation of a new mouse model to investigate the role of sv2a in epilepsy. PLoS ONE. doi:10.1371/journal.pone.0166525
* These authors have contributed equally to this work.

Neirinckx, V., Agirman, G., Coste, C., Marquet, A., Dion, V., Rogister, B., Franzen, R., & Wislet, S. (November 2015). Adult bone marrow mesenchymal and neural crest stem cells are chemoattractive and accelerate motor recovery in a mouse model of spinal cord injury. Stem Cell Research and Therapy, 6 (211). doi:10.1186/s13287-015-0202-2

Neirinckx, V. (2015). Etude des sous-populations de cellules souches stromales de la moelle osseuse, et de leur utilisation dans des protocoles de thérapie pour les maladies du système nerveux central [Doctoral thesis, Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/315399

Coste, C., Neirinckx, V., Gothot, A., Wislet, S., & Rogister, B. (2015). Are neural crest stem cells the missing link between hematopoietic and neurogenic niches? Frontiers in Cellular Neuroscience. doi:10.3389/fncel.2015.00218

Coste, C., Neirinckx, V., Rogister, B., Gothot, A., & Wislet, S. (2015). Human Adult Bone Marrow and Adipose Tissue Present Stem Cells with Neural Crest Characteristics. Cytotherapy. doi:10.1016/j.jcyt.2015.03.427

Neirinckx, V., Agirman, G., Coste, C., Rogister, B., Franzen, R., & Wislet, S. (2015). Exploring the secretome of bone marrow mesenchymal and neural crest-derived stem cells for treating spinal cord injuries. Cytotherapy. doi:10.1016/j.jcyt.2015.03.502

Neirinckx, V. (11 March 2015). Adult bone marrow stem cells-derived chemokines for treating spinal cord injuries [Paper presentation]. European Winter Conference on Brain Research, Brides-les-Bains, France.

Wislet, S., Coste, C., Neirinckx, V., & Rogister, B. (March 2015). Differential membrane marker expression in adult rodent bone marrow mesenchymal and neural crest stem cells [Poster presentation]. International Society for Cellular therapy 2015, Las Vegas, United States.

Coste, C., Neirinckx, V., Rogister, B., Gothot, A., & Wislet, S. (21 January 2015). Human Adult Bone Marrow and Adipose Tissue Present Stem Cells with Neural Crest Characteristics [Poster presentation]. GIGA DAY.

Neirinckx, V., Agirman, G., Marquet, A., Coste, C., Dion, V., Rogister, B., Franzen, R., & Wislet, S. (17 November 2014). Specific properties of bone marrow mesenchymal and neural crest-derived stem cells: Relevance in spinal cord injury therapy [Poster presentation]. Neuroscience 2014, Washington DC, United States.

Neirinckx, V., Agirman, G., Rogister, B., Franzen, R., & Wislet, S. (25 September 2014). Bone marrow mesenchymal and neural crest-derived stem cells have distinct secretomes, which are both relevant for spinal cord injury therapy [Paper presentation]. 9th Congress of the International Society for NeuroImmunoModulation.

Neirinckx, V., Coste, C., Franzen, R., Gothot, A., Rogister, B., & Wislet, S. (28 August 2014). Neutrophil contribution to spinal cord injury and repair. Journal of Neuroinflammation, 11 (1). doi:10.1186/s12974-014-0150-2

Neirinckx, V., CANTINIEAUX, D., Coste, C., Rogister, B., Franzen, R., & Wislet, S. (2014). Spinal Cord Injuries – How Could Adult Mesenchymal and Neural Crest Stem Cells Take Up the Challenge? Stem Cells. doi:10.1002/stem.1579

Neirinckx, V., Rogister, B., Franzen, R., & Wislet, S. (2014). Bone marrow stromal stem cells transplantation in mice with acute spinal cord injury. Methods in Molecular Biology, 1213. doi:10.1007/978-1-4939-1453-1_21

Coste, C., Neirinckx, V., Manguette, J., Rogister, B., Gothot, A., & Wislet, S. (05 December 2013). In vitro and in vivo Characterization of Adult Bone Marrow Neural Crest Stem Cells and their Implication in Hematopoietic Support [Poster presentation]. Journée Télévie, Bruxelles, Belgium.

Coste, C., Neirinckx, V., Manguette, J., Rogister, B., Gothot, A., & Wislet, S. (12 September 2013). In vitro and in vivo Characterization of Adult Bone Marrow Neural Crest Stem Cells and their Implication in Hematopoietic Support [Poster presentation]. EURON, Liège, Belgium.

Neirinckx, V. (12 September 2013). Adult bone marrow stem cells in neurological diseases: Protect or repair? [Paper presentation]. EURON PhD days 12-13th Sept 2013.

Coste, C., Neirinckx, V., Manguette, J., Rogister, B., Gothot, A., & Wislet, S. (31 May 2013). In vitro and in vivo Characterization of Adult Bone Marrow Neural Crest Stem Cells [Poster presentation]. Belgian society of neurosciences, Bruxelles, Belgium.

Neirinckx, V., Marquet, A., Coste, C., Rogister, B., & Wislet, S. (31 May 2013). Adult Bone Marrow Neural Crest Stem Cells and Mesenchymal Stem Cells are not able to Replace Lost Neurons in Acute MPTP-lesioned Mice. PLoS ONE, 8 (5). doi:10.1371/journal.pone.0064723

Neirinckx, V. (12 April 2013). Adult Bone Marrow Neural Crest and Mesenchymal Stem Cells : Which Role in Therapy of Neurological Pathologies ? [Paper presentation]. Cell-based therapies in Central Nervous System Pathology, Hasselt, Belgium.

Neirinckx, V., Coste, C., Rogister, B., & Wislet, S. (02 April 2013). Adult Mesenchymal Stem Cells, Adult Neural Crest Stem Cells and Therapy of Neurological Pathologies: a State of Play. Stem Cells Translational Medicine, 2 (4), 284-296. doi:10.5966/sctm.2012-0147

Neirinckx, V., Coste, C., Rogister, B., & Wislet, S. (2013). Neural fate of Mesenchymal Stem Cells and Neural Crest Stem Cells : Which ways to get neurons for cell therapy purpose ? In Trends in cell signaling pathways in neuronal fate decision (pp. 327-358). Croatia: InTech.

Coste, C., Neirinckx, V., Rogister, B., Gothot, A., & Wislet, S. (28 January 2013). In vitro and in vivo Characterization of Adult Bone Marrow Neural Crest Stem Cells and their Implication in Hematopoietic Support [Poster presentation]. GIGA Day, Liège, Belgium.

Neirinckx, V., Marquet, A., Poulet, C., Laudet, E., Coste, C., Manguette, J., Rogister, B., & Wislet, S. (28 January 2013). Adult Bone Marrow Neural Crest and Mesenchymal Stem Cells : Which Role in Therapy of Neurological Pathologies ? [Poster presentation]. GIGA Day 2013.

Coste, C., Neirinckx, V., Rogister, B., Gothot, A., & Wislet, S. (10 December 2012). In vitro and in vivo Characterization of Adult Bone Marrow Neural Crest Stem Cells and their Implication in Hematopoietic Support [Poster presentation]. TELEVIE's Researchers Seminar, Liège, Belgium.

Wislet, S.* , Poulet, C.* , Neirinckx, V., Hennuy, B., Swingland, J., Laudet, E., Sommer, L., Shakhova, O., Bours, V., & Rogister, B. (October 2012). In Vivo Tumorigenesis Was Observed after Injection of In Vitro Expanded Neural Crest Stem Cells Isolated from Adult Bone Marrow. PLoS ONE, 7 (10), 46425. doi:10.1371/journal.pone.0046425
* These authors have contributed equally to this work.

Wislet, S., Laudet, E., Neirinckx, V., Alix, P., Leprince, P., glejzer, A., Poulet, C., Hennuy, B., Sommer, L., Shakhova, O., & Rogister, B. (August 2012). [RETRACTED] Mesenchymal stem cells and neural crest stem cells from adult bone marrow: characterization of their surprising similarities and differences. Cellular and Molecular Life Sciences, 69 (15), 2593-2608. doi:10.1007/s00018-012-0937-1

Neirinckx, V., Laudet, E., Rogister, B., & Wislet, S. (04 May 2012). Validation of Adult Bone Marrow Stromal Cells in Cellular Therapy Protocols, using a Mouse Model for Parkinson’s Disease [Poster presentation]. GIGA Day 2012.

Neirinckx, V., Rogister, B., & Wislet, S. (2012). Adult neural crest stem cells and neuronal fate decision. In Trends in cell signaling pathways in neuronal fate decision. Croatia: InTech.

Wislet-Gendebien, S., Laudet, E., Neirinckx, V., & Rogister, B. (2011). Adult bone marrow: which stem cells for cellular therapy protocols in neurodegenerative disorders? Journal of Biomedicine and Biotechnology.

Neirinckx, V. (2011). Etude in vivo de la plasticité phénotypique nerveuse des cellules souches dérivées de la moelle osseuse adulte [Master’s dissertation, ULiège - Université de Liège]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/136788

Glejzer, A., Neirinckx, V., Rogister, B., & Wislet, S. (2011). Neural crest stem cells from adult bone marrow: a new source for cell replacement therapy? In S. Wislet (Ed.), Advance in Regenerative Medicine (pp. 3-18). Croatia: Intech-open access publisher.