Publications and communications of Kateryna Shostak

Chen, D., Nemazanyy, I., Peulen, O., Shostak, K., Xu, X., Tang, S. C., Wathieu, C., Turchetto, S., Tielens, S., Nguyen, L., Close, P., Desmet, C., Klein, S., Florin, A., Büttner, R., Petrellis, G., Dewals, B. G., & Chariot, A. (2022). Elp3-mediated codon-dependent translation promotes mTORC2 activation and regulates macrophage polarization. EMBO Journal, 109353. doi:10.15252/embj.2021109353

Jeschke, J., Collignon, E., Al Wardi, C., Krayem, M., Bizet, M., Jia, Y., Garaud, S., Wimana, Z., Calonne, E., Hassabi, B., Morandini, R., Deplus, R., Putmans, P., Dube, G., Singh, N. K., Koch, A., Shostak, K., Rizzotto, L., Ross, R. L., ... Fuks, F. (June 2021). Downregulation of the FTO m6A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors. Nature Cancer, 2 (6), 611-628. doi:10.1038/s43018-021-00223-7

Rapino, F.* , ZHOU, Z.* , RONCERO SANCHEZ, A. M.* , Joiret, M., Seca, C., El Hachem, N., Valenti, G., Latini, S., Shostak, K., Geris, L., Li, P., Huang, G., Mazzucchelli, G., Baiwir, D., Desmet, C., Chariot, A., Georges, M., & Close, P. (2021). Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate. Nature Communications, 12 (1), 2170. doi:10.1038/s41467-021-22254-5
* These authors have contributed equally to this work.

Shostak, K., Jiang, Z., CHARLOTEAUX, B., Mayer, A., Habraken, Y., Tharun, L., Klein, S., Xu, X., Duong, H. Q., Vislovukh, A., Close, P., Florin, A., Rambow, F., Marine, J.-C., Büttner, R., & Chariot, A. (09 March 2020). The X-linked trichothiodystrophy-causing gene RNF113A links the spliceosome to cell survival upon DNA damage. Nature Communications, 11 (1). doi:10.1038/s41467-020-15003-7

Delaunay, S., Rapino, F., Tharun, L., Zhou, Z., Heukamp, L., Termathe, M., Shostak, K., Klevernic, I., Florin, A., Desmecht, H., Desmet, C., Nguyen, L., Leiden, S. A., Willis, A. E., Buettner, R., Chariot, A., & Close, P. (October 2016). ELP3 links tRNA modification to IRES-dependent translation of LEF-1 to promote metastasis in breast cancer. Journal of Experimental Medicine, 213, 2503-2523. doi:10.1084/jem.20160397

Göktuna, S., Shostak, K., Chau, T.-L., Heukamp, L., Hennuy, B., Duong, H. Q., LADANG, A., Close, P., Klevernic, I., Olivier, F., Florin, A., Ehx, G., Baron, F., Vandereyken, M., Rahmouni, S., Vereecke, L., van Loo, G., Büttner, R., Greten, F., & Chariot, A. (2016). The Prosurvival IKK-Related Kinase IKK« Integrates LPS and IL17A Signaling Cascades to Promote Wnt-Dependent Tumor Development in the Intestine. Cancer Research, 76, 2587-99. doi:10.1158/0008-5472.CAN-15-1473

Shostak, K., & Chariot, A. (June 2015). EGFR and NF-kB: partners in cancer. Trends in Molecular Medicine, 21, 385-393. doi:10.1016/j.molmed.2015.04.001

Shostak, K., Zhang, X., Hubert, P., Göktuna, S., Jiang, Z., Klevernic, I., Hildebrand, J., Roncarati, P., Hennuy, B., Ladang, A., SOMJA, J., Gothot, A., Close, P., Delvenne, P., & Chariot, A. (2014). NF-kappaB-induced KIAA1199 promotes survival through EGFR signalling. Nature Communications, 5, 5232. doi:10.1038/ncomms6232

Stellzig, J., Chariot, A., Shostak, K., Göktuna, S., Renner, F., Acker, T., Pagenstecher, A., & Schmitz, M. (11 November 2013). Deregulated expression of TANK in glioblastomas triggers pro-tumorigenic ERK1/2 and AKT signaling pathways. Observatoire (L'), e79. doi:10.1038/oncsis.2013.42

Shostak, K., & Chariot, A. (26 July 2011). NF-kB, stem cells and breast cancer: the links get stronger. Breast Cancer Research, 13 (4), 214. doi:10.1186/bcr2886

Keutgens, A., Shostak, K., Close, P., Zhang-Shao, X., Hennuy, B., Aussems, M., Chapelle, J.-P., Viatour, P., Gothot, A., Fillet, M., & Chariot, A. (August 2010). The repressing function of the oncoprotein BCL-3 requires CtBP while its polyubiquitination and degradation involve the E3 ligase TBLR1. Molecular and Cellular Biology, 30, 4006-4021. doi:10.1128/MCB.01600-09

Keutgens, A., Zhang-Shao, X., Shostak, K., Robert, I., Olivier, S., Vanderplasschen, A., Chapelle, J.-P., Viatour, P., Merville, M.-P., Bex, F., Gothot, A., & Chariot, A. (2010). BCL-3 degradation involves its polyubiquitination through a FBW7-independent pathway and its binding to the proteasome subunit PSMB1. Journal of Biological Chemistry, 285 (33), 25831–25840. doi:10.1074/jbc.M110.112128

Dmitrenko, V., Shostak, K., Boyko, O., Khomenko, O., Rozumenko, V., Malisheva, T., Shamayev, M., Zozulya, Y., & Kavsan, V. (2005). Reduction of the transcription level of the mitochondrial genome in human glioblastoma. Cancer Letters, 218 (1), 99-107. doi:10.1016/j.canlet.2004.07.001

Kavsan, V., Shostak, K., Dmitrenko, V., Zozulya, Y., Rozumenko, V., & Demotes-Mainard, J. (2005). Characterization of genes with increased expression in human glioblastomas. Tsitologiia i Genetika, 39 (6), 37-49.

Shostak, K., Dmitrenko, V. V., Garifulin, O. M., Rozumenko, V. D., Khomenko, O. V., Zozulya, Y. A., Zehetner, G., & Kavsan, V. M. (2003). Downregulation of putative tumor suppressor gene TSC-22 in human brain tumors. Journal of Surgical Oncology, 82 (1), 57-64. doi:10.1002/jso.10180

Shostak, K., Labunskyy, V., Dmitrenko, V., Malisheva, T., Shamayev, M., Rozumenko, V., Zozulya, Y., Zehetner, G., & Kavsan, V. (2003). HC gp-39 gene is upregulated in glioblastomas. Cancer Letters, 198 (2), 203-10. doi:10.1016/S0304-3835(03)00310-0