Publications and communications of Ana Maria Amoroso

Dauvrin, T., Joris, B., Franck, F., Remacle, C., Amoroso, A. M., & Gerards, T. (02 February 2024). Chlorophyllide derivatives for use in the prevention or treatment of bacterial infection.

Dauvrin, T., Joris, B., Franck, F., Remacle, C., Amoroso, A. M., & Gerards, T. (31 January 2024). CHLOROPHYLLIDE DERIVATIVES FOR USE IN THE PREVENTION OR TREATMENT OF BACTERIAL INFECTION.

Wan, H., Ben Othman, R., Le Corre, L., Poinsot, M., Oliver, M., Amoroso, A. M., Joris, B., Touzé, T., Auger, R., Calvet-Vitale, S., Bosco, M., & Gravier-Pelletier, C. (02 September 2022). New MraYAA Inhibitors with an Aminoribosyl Uridine Structure and an Oxadiazole. Antibiotics, 11 (9), 1189. doi:10.3390/antibiotics11091189

Oliver, M., Le Corre, L., Poinsot, M., Bosco, M., Wan, H., Amoroso, A. M., Joris, B., Bouhss, A., Calvet-Vitale, S., & Gravier-Pelletier, C. (08 March 2022). A Sub-Micromolar MraYAA Inhibitor with an Aminoribosyl Uridine Structure and a (S,S)-Tartaric Diamide: Synthesis, Biological Evaluation and Molecular Modeling. Molecules, 27 (6), 1769. doi:10.3390/molecules27061769

Oliver, M., Le Corre, L., Poinsot, M., Corio, A., Madegard, L., Bosco, M., Amoroso, A. M., Joris, B., Auger, R., Touzé, T., Bouhss, A., Calvet-Vitale, S., & Gravier-Pelletier, C. (2021). Synthesis, biological evaluation and molecular modeling of urea-containing MraY inhibitors. Organic and Biomolecular Chemistry, 19 (26), 5844-5866. doi:10.1039/d1ob00710f

Decuyper, L., Jukič, M., Sosič, I., Amoroso, A. M., Verlaine, O., Joris, B., Gobec, S., & D'hooghe, M. (02 January 2020). Synthesis and Penicillin-binding Protein Inhibitory Assessment of Dipeptidic 4-Phenyl-β-lactams from α-Amino Acid-derived Imines. Chemistry: An Asian Journal, 15 (1), 51-55. doi:10.1002/asia.201901470

Decuyper, L., Magdalenić, K., Verstraete, M.-B., Jukič, M., Sosič, I., Sauvage, E., Amoroso, A. M., Verlaine, O., Joris, B., Gobec, S., & D'hooghe, M. (09 October 2019). α-Unsaturated 3-Amino-1-carboxymethyl-β-lactams as Bacterial PBP Inhibitors: Synthesis and Biochemical Assessment. Chemistry, 25 (70), 16128 - 16140. doi:10.1002/chem.201904139

Decuyper, L., Deketelaere, S., Vanparys, L., Jukič, M., Sosič, I., Sauvage, E., Amoroso, A. M., Verlaine, O., Joris, B., Gobec, S., & D'hooghe, M. (12 October 2018). In Silico Design and Enantioselective Synthesis of Functionalized Monocyclic 3-Amino-1-carboxymethyl-β-lactams as Inhibitors of Penicillin-Binding Proteins of Resistant Bacteria. Chemistry, 24 (57), 15254-15266. doi:10.1002/chem.201801868

Di Gregorio, S., Fernandez, S., Cuirolo, A., Verlaine, O., Amoroso, A. M., Mengin-Lecreulx, D., Famiglietti, A., Joris, B., & Mollerach, M. (January 2017). Different Vancomycin-Intermediate Staphylococcus aureus Phenotypes Selected from the Same ST100-hVISA Parental Strain. Microbial Drug Resistance: Mechanism, Epidemiology, and Disease, 23 (1), 44-50. doi:10.1089/mdr.2016.0160

Maréchal, M., Amoroso, A. M., Morlot, C., Vernet, T., Coyette, J., & Joris, B. (12 October 2016). Enterococcus hirae LcpA (Psr), a new peptidoglycan-binding protein localized at the division site. BMC Microbiology, 16 (1), 239. doi:10.1186/s12866-016-0844-y

Fer, M., Bouhss,, A. B., Patrão, M., Le Corre, L., Pietrancosta, N., Amoroso, A. M., Joris, B., Mengin-Lecreulx, D., Calvet-Vitale, S., & Gravier-Pelletier, C. (May 2015). 5′-Methylene-triazole-substituted-aminoribosyl uridines as MraY inhibitors: synthesis, biological evaluation and molecular modeling. Organic and Biomolecular Chemistry, 13 (26), 7193. doi:10.1039/c5ob00707k

Terrasse, R., Amoroso, A. M., Vernet, T., & Di Guilmi, A. M. (2015). Streptococcus pneumoniae GAPDH Is Released by Cell Lysis and Interacts with Peptidoglycan. PLoS ONE, 10 (4), 0125377. doi:10.1371/journal.pone.0125377

Vassal-Stermann, E., Lacroix, M., Gout, E., Laffly, E., Pedersen, C. M., Martin, L., Amoroso, A. M., Schmidt, R. R., Zahringer, U., Gaboriaud, C., Di Guilmi, A.-M., & Thielens, N. M. (2014). Human L-ficolin recognizes phosphocholine moieties of pneumococcal teichoic acid. Journal of Immunology, 193 (11), 5699-708. doi:10.4049/jimmunol.1400127

Henry, X., Verlaine, O., Amoroso, A. M., Coyette, J., & Joris, B. (December 2013). Activity of ceftaroline against Enterococcus faecium PBP5. Antimicrobial Agents and Chemotherapy, 57 (12), 6358. doi:10.1128/AAC.00923-13

Amoroso, A. M., Boudet, J., Berzigotti, S., Duval, V., Teller, N., Mengin-Lecreulx, D., Luxen, A., Simorre, J.-P., & Joris, B. (2012). A peptidoglycan fragment triggers beta-lactam resistance in Bacillus licheniformis. PLoS Pathogens, 8 (3), 1002571. doi:10.1371/journal.ppat.1002571

Berzigotti, S., Benlafya, K., Sepulchre, J., Amoroso, A. M., & Joris, B. (2012). Bacillus licheniformis BlaR1 L3 loop is a Zinc metalloprotease activated by self-proteolysis. PLoS ONE, 7, 36400. doi:10.1371/journal.pone.0036400

Zervosen, A., Bouillez, A., Herman, A., Amoroso, A. M., Joris, B., Sauvage, E., Charlier, P., & Luxen, A. (2012). Synthesis and evaluation of boronic acids as inhibitors of Penicillin Binding Proteins of classes A, B and C. Bioorganic and Medicinal Chemistry, 20 (12), 3915-24. doi:10.1016/j.bmc.2012.04.018

Sosic, I., Barreteau, H., Simcic, M., Sink, R., Cesar, J., Zega, A., Grdadolnik, S. G., Contreras-Martel, C., Dessen, A., Amoroso, A. M., Joris, B., Blanot, D., & Gobec, S. (2011). Second-generation sulfonamide inhibitors of D-glutamic acid-adding enzyme: activity optimisation with conformationally rigid analogues of D-glutamic acid. European Journal of Medicinal Chemistry, 46 (7), 2880-94. doi:10.1016/j.ejmech.2011.04.011

Turk, S., Verlaine, O., Gerards, T., Zivec, M., Humljan, J., Sosic, I., Amoroso, A. M., Zervosen, A., Luxen, A., Joris, B., & Gobec, S. (2011). New noncovalent inhibitors of penicillin-binding proteins from penicillin-resistant bacteria. PLoS ONE, 6 (5), 19418. doi:10.1371/journal.pone.0019418

Kern, T., Giffard, M., Hediger, S., Amoroso, A. M., Giustini, C., Khai Bui, N., Joris, B., Vollmer, & Simorre, J.-P. (2010). Dynamics Characterization of Fully Hydrated Bacterial Cell Walls by Solid-State NMR: Evidence for Cooperative Binding of Metal Ions. Journal of the American Chemical Society, 132, 10911-10919. doi:10.1021/ja104533w

Sauvage, E., Zervosen, A., Dive, G., Herman, R., Amoroso, A. M., Joris, B., Fonzé, E., Pratt, R., Luxen, A., Charlier, P., & Kerff, F. (2009). Structural basis of the inhibition of class A beta-lactamases and penicillin-binding proteins by 6-beta-iodopenicillanate. Journal of the American Chemical Society, 131 (42), 15262-15269. doi:10.1021/ja9051526

Rubinstein, G., Amoroso, A. M., Bavdaz, B., De Bunder, S., Blazquez, N., & Gutkind, G. O. (2005). Low macrolide resistance in Streptococcus pyogenes in Southern Argentina. International Journal of Antimicrobial Agents, 25 (5), 450-2. doi:10.1016/j.ijantimicag.2005.01.010

Duez, C., Hallut, S., Rhazi, N., Amoroso, A. M., Bouillenne, F., & Coyette, J. (July 2004). The ponA gene of Enterococcus faecalis JH2-2 codes for a low-affinity class a penicillin-binding protein. Journal of Bacteriology, 186 (13), 4412-4416. doi:10.1128/JB.186.13.4412-4416.2004

Martinez, S., Amoroso, A. M., Famiglietti, A., de Mier, C., Vay, C., & Gutkind, G. O. (2004). Genetic and phenotypic characterization of resistance to macrolides in Streptococcus pyogenes from Argentina. International Journal of Antimicrobial Agents, 23 (1), 95-8. doi:10.1016/j.ijantimicag.2003.05.009

Sapunaric, F., Franssen, C., Stefanic, P., Amoroso, A. M., Dardenne, O., & Coyette, J. (2003). Redefining the role of psr in beta-lactam resistance and cell autolysis of Enterococcus hirae. Journal of Bacteriology, 185 (20), 5925-35. doi:10.1128/JB.185.20.5925-5935.2003

Duez, C., Zorzi, W., Sapunaric, F., Amoroso, A. M., Thamm, I., & Coyette, J. (September 2001). The Penicillin Resistance of Enterococcus Faecalis Jh2-2r Results from an Overproduction of the Low-Affinity Penicillin-Binding Protein Pbp4 and Does Not Involve a Psr-Like Gene. Microbiology, 147 (Pt 9), 2561-9. doi:10.1099/00221287-147-9-2561

Amoroso, A. M., Demares, D., Mollerach, M., Gutkind, G., & Coyette, J. (2001). All detectable high-molecular-mass penicillin-binding proteins are modified in a high-level beta-lactam-resistant clinical isolate of Streptococcus mitis. Antimicrobial Agents and Chemotherapy, 45 (7), 2075-81. doi:10.1128/AAC.45.7.2075-2081.2001

Amoroso, A. M., & Gutkind, G. O. (2001). Chromogenic detection of aminoglycoside phosphotransferases. Methods in Molecular Medicine, 48, 113-7. doi:10.1385/1-59259-077-2:113