Publications and communications of Maximilien Fleron

Veiga, R.* , De Vuyst, L.* , Poulet, C.* , Neumann, J., Bücken, L., Prezzemolo, T., Willemsen, M., Vanderschueren, S., Matthys, P., Chabaane, E., Fleron, M., Cobraiville, G., Baiwir, D., Mazzucchelli, G., Immunome Project Consortium for Autoinflammatory Disorders (ImmunAID), Fautrel, B., Wouters, C., de Seny, D.* , Humblet-Baron, S.* , & Liston, A.*. (2026). Adult patients with autoinflammation of unknown origin partially phenocopy the immune presentation of Still's disease. Nature Communications. doi:10.1038/s41467-026-70895-1
* These authors have contributed equally to this work.

Baiwir, D., Kune, C., Fleron, M., Eppe, G., & Mazzucchelli, G. (18 June 2025). Trap-Refocusing-Elute nano liquid chromatography: how to take advantage of both direct injection and trap-elute mode? [Poster presentation]. EuPA 2025, Saint-Malo, France.

Berkal, M. A., Burat, B., Fleron, M., Baiwir, D., Sophie Gohy, Eppe, G., & Mazzucchelli, G. (17 June 2025). Sweat Proteomics: A Noninvasive Approach for Biomarker Discovery with Optimized and Fully Automated Sample Preparation [Poster presentation]. European Proteomics Association (EuPA), Palais du Grand Large, Saint-Malo, France, France.

Kune, C., Gholizadeh, A., Tielens, S., Fleron, M., Baiwir, D., Vandormael, D., Nguyen, L., Eppe, G., Gilet, T., & Mazzucchelli, G. (17 June 2025). Boosting Proteomics at Single-Cell Level: Enhancing Peptide Recovery, Automation, Chromatographic Robustness and Performance [Paper presentation]. European Proteomics Association (EuPA) 2025, Saint Malo, France.

Kune, C., Tielens, S., Fleron, M., Baiwir, D., Berkal, M. A., Nguyen Laurent, Eppe, G., & Mazzucchelli, G. (17 June 2025). Smarter Libraries for Faster DIA: A Sequential Digestion Strategy to Enhance Proteome Coverage in DDA-based Spectral Libraries [Poster presentation]. European Proteomics Association (EuPA), Saint-Malo, France.

Kune, C., Tielens, S., Baiwir, D., Fleron, M., Vandormael, D., Eppe, G., Nguyen, L., & Mazzucchelli, G. (25 February 2025). SIGNIFICANT IMPACT OF CONSUMABLE MATERIAL AND BUFFER COMPOSITION FOR LOW-CELL NUMBER PROTEOMIC SAMPLE PREPARATION. Analytical Chemistry, 97 (7), 3836 - 3845. doi:10.1021/acs.analchem.4c03709

Hodeige, M., Kune, C., Bertrand, V., Fleron, M., Baiwir, D., Sounni, N. E., Eppe, G., Gatto, L., & Mazzucchelli, G. (24 January 2025). Linking spatial to functional proteomics on heterogeneous samples: The “pixel-by-pixel” shotgun proteomic approach [Poster presentation]. Molsys day, Liège, Belgium.

Burat, B., Berkal, M. A., Kune, C., Fleron, M., Baiwir, D., Sophie Gohy, Eppe, G., & Mazzucchelli, G. (06 December 2024). Comprehensive Sweat Proteome Characterization and Identification of Cystic Fibrosis Biomarkers: Optimizing Sample Preparation for a new MS-Based Proteomic Approach [Paper presentation]. Belgian Proteomics Association Conference (BePAc 2024), Ghent, Belgium.

Hodeige, M., Kune, C., Fleron, M., Baiwir, D., Sounni, N. E., Eppe, G., Gatto, L., & Mazzucchelli, G. (05 December 2024). Linking spatial to functional proteomics on heterogeneous samples: The “pixel-by-pixel” shotgun proteomic approach [Paper presentation]. Belgian Proteomics Association Conference, Gent, Belgium.

Pierre, N., Huynh-Thu, V. A., Baiwir, D., Mazzucchelli, G., Fleron, M., Trzpiot, L., Eppe, G., De Pauw, E., Laharie, D., Satsangi, J., Bossuyt, P., Vuitton, L., Vieujean, S., Colombel, J.-F., Meuwis, M.-A., Louis, E., & GETAID and the SPARE-Biocycle research group. (2024). External validation of serum biomarkers predicting short-term and mid/long-term relapse in patients with Crohn's disease stopping infliximab. Gut, 2024-332648. doi:10.1136/gutjnl-2024-332648

Pierre, N., Huynh-Thu, V. A., Baiwir, D., VIEUJEAN, S., Bequet, E., Reenaers, C., Van Kemseke, C., Salée, C., Massot, C., Fleron, M., Mazzucchelli, G., Trzpiot, L., Eppe, G., De Pauw, E., Louis, E., & Meuwis, M.-A. (2024). Serum proteome signatures associated with ileal and colonic ulcers in Crohn's disease. Journal of Proteomics, 105199. doi:10.1016/j.jprot.2024.105199

Burat, B., Reynaerts, A., Baiwir, D., Fleron, M., Gohy, S., Eppe, G., Leal, T.* , & Mazzucchelli, G.*. (31 July 2022). Sweat Proteomics in Cystic Fibrosis: Discovering Companion Biomarkers for Precision Medicine and Therapeutic Development. Cells, 11 (15), 2358. doi:10.3390/cells11152358
* These authors have contributed equally to this work.

Lebeau, A.* , Bruyère, D.* , RONCARATI, P., Peixoto, P., Hervouet, E., COBRAIVILLE, G., Taminiau, B., Masson, M., Gallego, C., Mazzucchelli, G., Smargiasso, N., Fleron, M., Baiwir, D., Hendrick, E., Pilard, C., Lerho, T., Reynders, C., Ancion, M., GREIMERS, R., ... Herfs, M. (28 February 2022). HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources. Nature Communications, 13 (1), 1076. doi:10.1038/s41467-022-28724-8
* These authors have contributed equally to this work.

Burat, B.* , Reynaerts, A.* , Baiwir, D., Fleron, M., Eppe, G., Leal, T.* , & Mazzucchelli, G.*. (08 October 2021). Characterization of the Human Eccrine Sweat Proteome—A Focus on the Biological Variability of Individual Sweat Protein Profiles. International Journal of Molecular Sciences, 22 (19). doi:10.3390/ijms221910871
* These authors have contributed equally to this work.

Alevra Sarika, N.* , Payen, V.* , Fleron, M., Ravau, J., Brusa, D., Najimi, M., De Pauw, E., Eppe, G., Mazzucchelli, G., Sokal, E., des Rieux, A., & El Taghdouini, A. (30 May 2020). Human Liver-Derived Extracellular Matrix for the Culture of Distinct Human Primary Liver Cells. Cells, 9(6). doi:10.3390/cells9061357
* These authors have contributed equally to this work.

Mazzucchelli, G., Gabelica, V., Smargiasso, N., Fleron, M., Ashimwe, W., Rosu, F., De Pauw-Gillet, M.-C., Riou, J.-F., & De Pauw, E. (2008). Proteome alteration induced by hTERT transfection of human fibroblast cells. Proteome Science, 6 (1), 12. doi:10.1186/1477-5956-6-1