Publications and communications of Nicolas Thelen

Articles in scientific journals as first or last author

Thelen, N., & Thiry, M. (19 March 2026). Relationships between clusters of interchromatin granules and chromatin fibers. Histochemistry and Cell Biology, 164 (1). doi:10.1007/s00418-026-02465-x

Thelen, N., Defourny, J., Lafontaine, D., & Thiry, M. (2021). Visualization of chromatin in the yeast nucleus and nucleolus using hyperosmotic shock. International Journal of Molecular Sciences. doi:10.3390/ijms22031132

Thelen, N., Breuskin, I., Malgrange, B., & Thiry, M. (2009). Early identification of inner pillar cells during rat cochlear development. Cell and Tissue Research, 337 (1), 1-14. doi:10.1007/s00441-009-0810-1

Articles in scientific journals as co-author

Wentling, M., Yakhlef Sanchez, A., Thelen, N., Senarisoy, M., Hogg, M., Condamine, S., Lelli, A., Wysocka, E., Patni, P., Vitry, S., Yildizhan, K. Y., Le Gal, S., Nouaille, S., Bowl, M. R., Thiry, M., Dulon, D., Delmaghani, S., & El-Amraoui, A. (2026). Compensatory Interplay Between Clarin-1 and Clarin-2 Deafness-Associated Proteins Governs Phenotypic Variability in Hearing. Advanced Science, 21853. doi:10.1002/advs.202521853

Boclinville, A., Vandevenne, M., Pressia, A., Thelen, N., Thiry, M., Jacobs, N., Brans, A., Fillet, M., & Servais, A.-C. (January 2026). Isoelectric point determination by icIEF as quality control for structural and functional characterization of HPV16 virus-like particles. Analytica Chimica Acta, 1383, 344904. doi:10.1016/j.aca.2025.344904

Horne, J., Beckers, P., Kemik, K., De Bleye, C., Sacré, P. Y., Thelen, N., Hubert, P., Ziemons, E.* , & Hubert, C.*. (2024). Determination of Size, Size Distribution, and Concentration of Nanoparticles Using ICP‐MS in the Context of SERS Substrates. Journal of Raman Spectroscopy. doi:10.1002/jrs.6746
* These authors have contributed equally to this work.

Horne, J., Beckers, P., Sacre, P.-Y., De Bleye, C., Francotte, P., Thelen, N., Hubert, P., Ziemons, E.* , & Hubert, C.*. (22 July 2024). Optimisation of a Microwave Synthesis of Silver Nanoparticles by a Quality by Design Approach to Improve SERS Analytical Performances. Molecules, 29 (14), 3442. doi:10.3390/molecules29143442
* These authors have contributed equally to this work.

Boclinville, A., Vandevenne, M., Ambroggio, E., Thelen, N., Thiry, M., Jacobs, N., Brans, A., Fillet, M., & Servais, A.-C. (April 2024). Interaction studies between human papillomavirus virus-like particles and laminin 332 by affinity capillary electrophoresis assisted by bio-layer interferometry. Talanta, 270, 125602. doi:10.1016/j.talanta.2023.125602

Raick, X., Thelen, N., Compère, P., & Parmentier, E. (2022). Ultrastructure of sonic muscles of piranhas (Serrasalmidae). Journal of Morphology, 283 (4), 395-405. doi:10.1002/jmor.21450

Renauld, J., Thelen, N., Bartholomé, O., Malgrange, B., & Thiry, M. (2021). Dispensability of tubulin acetylation for 15-protofilament microtubule formation in the mammalian cochlea. Cell Structure and Function. doi:10.1247/csf.20057

Bartholomé, O., Franck, C., Piscicelli, P., Lalun, N., Defourny, J., Renauld, J., Thelen, N., Lamaye, F., Ploton, D., & Thiry, M. (September 2019). Relationships between the structural and functional organization of the turtle cell nucleolus. Journal of Structural Biology, 208 (3), 107398. doi:10.1016/j.jsb.2019.09.015

Beaufrère, A., Bessières, B., Bonnière, M., Driessen, M., Alfano, C., Couderc, T., Thiry, M., Thelen, N., Lecuit, M., Attié-Bitach, T., Vekemans, M., Ville, Y., Nguyen, L., Leruez-Ville, M., & Encha-Razavi, F. (2019). A clinical and histopathological study of malformations observed in fetuses infected by the Zika virus. Brain Pathology, 29 (1), 114-125. doi:10.1111/bpa.12644

Defourny, J., Thelen, N., & Thiry, M. (2019). Cochlear connexin 30 homomeric and heteromeric channels exhibit distinct assembly mechanisms. Mechanisms of Development. doi:10.1016/j.mod.2018.10.001

Defourny, J., Thelen, N., & Thiry, M. (2019). Actin-independent trafficking of cochlear connexin 26 to non-lipid raft gap junction plaques. Hearing Research. doi:10.1016/j.heares.2019.01.020

Freeman, S.* , Mateo Sánchez, S.* , Pouyo, R., Van Lerberghe, P.-B., Hanon, K., Thelen, N., Thiry, M., Morelli, G., Van Hees, L., Laguesse, S., Chariot, A., Nguyen, L., Delacroix, L.* , & Malgrange, B.*. (2019). Proteostasis is essential during cochlear development for neuron survival and hair cell polarity. EMBO Reports, 20 (9). doi:10.15252/embr.201847097
* These authors have contributed equally to this work.

Yazdani, R., Shams-Bakhsh, M., Hassani-Mehraban, A., Arab, S. S., Thelen, N., Thiry, M., Crommen, J., Fillet, M., Jacobs, N., Brans, A., & Servais, A.-C. (2019). Production and characterization of virus-like particles of grapevine fanleaf virus presenting L2 epitope of human papillomavirus minor capsid protein. BMC Biotechnology, 19 (1), 81. doi:10.1186/s12896-019-0566-y

Lebrun, M., Lambert, J., Riva, L., Thelen, N., Rambout, X., Blondeau, C., Thiry, M., Snoeck, R., Twizere, J.-C., Dequiedt, F., Andrei, G., & Sadzot-Delvaux, C. (17 July 2018). Varicella Zoster Virus ORF9p binding to cellular adaptor protein complex-1 is important for viral infectivity. Journal of Virology, 92 (15). doi:10.1128/JVI.00295-18

Gladwyn-Ng, I., Cordon-Barris, L., Alfano, C., Creppe, C., Couderc, T., Morelli, G., Thelen, N., America, M., Bessieres, B., Encha-Razavi, F., Bonniere, M., Suzuki, I. K., Flamand, M., Vanderhaeghen, P., Thiry, M., Lecuit, M., & Nguyen, L. (2018). Stress-induced unfolded protein response contributes to Zika virus-associated microcephaly. Nature Neuroscience, 21 (1), 63-71. doi:10.1038/s41593-017-0038-4

Bettonville, V., Nicol, J. T. J., Furst, T., Thelen, N., Piel, G., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (2017). Quantitation and biospecific identification of virus-like particles of human papillomavirus by capillary electrophoresis. Talanta, 175, 325-330. doi:10.1016/j.talanta.2017.07.046

Bettonville, V., Nicol, J., Thelen, N., Thiry, M., Fillet, M., Jacobs, N., & Servais, A.-C. (2016). Study of intact virus-like particles of human papillomavirus by capillary electrophoresis. Electrophoresis, 37, 579-586. doi:10.1002/elps.201500431

Michel, L., Dauby, P., Gobert, S., Graeve, M., Nyssen, F., Thelen, N., & Lepoint, G. (December 2015). Dominant amphipods of Posidonia oceanica seagrass meadows display considerable trophic diversity. Marine Ecology, 36 (4), 969-981. doi:10.1111/maec.12194

Delmaghani, S., Defourny, J., Aghaie, A., Beurg, M., Dulon, D., Thelen, N., Perfettini, I., Zelles, T., Aller, M., Meyer, A., Emptoz, A., Giraudet, F., Leibovici, M., Dartevelle, S., Soubigou, G., Thiry, M., Vizi, E. S., Safieddine, S., Hardelin, J.-P., ... Petit, C. (November 2015). Hypervulnerability to Sound Exposure through Impaired Adaptive Proliferation of Peroxisomes. Cell, 163 (4), 894-906. doi:10.1016/j.cell.2015.10.023

Renauld, J., Johnen, N., Thelen, N., Cloes, M., & Thiry, M. (2015). Spatio‑temporal dynamics of β‑tubulin isotypes during the development of the sensory auditory organ in rat. Histochemistry and Cell Biology. doi:10.1007/s00418-015-1350-2

Huyghe, A.* , Van Den Ackerveken, P.* , SACHELI, R., Prevot, P.-P., Thelen, N., Renauld, J., Thiry, M., Delacroix, L., Nguyen, L., & Malgrange, B. (2015). MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5. Cell Reports, 13, 31-42. doi:10.1016/j.celrep.2015.08.054
* These authors have contributed equally to this work.

Laguesse, S.* , Creppe, C.* , Nedialkova, D., Prevot, P.-P., Borgs, L., Huysseune, S., Franco, B., Duysens, G., Krusy, N., Lee, G., Thelen, N., Thiry, M., Close, P., Chariot, A., Malgrange, B., Leidel, S., Godin, J., & Nguyen, L. (2015). A dynamic unfolded protein response contributes to the control of cortical neurogenesis. Developmental Cell, 35, 553-567. doi:10.1016/j.devcel.2015.11.005
* These authors have contributed equally to this work.

Herman, J., Thelen, N., Smargiasso, N., Mailleux, A.-C., Luxen, A., Cloes, M., De Pauw, E., Chevigné, A., Galleni, M., & Dumez, M.-E. (2014). Der p 1 is the primary activator of Der p 3, Der p 6 and Der p 9 the proteolytic allergens produced by the house dust mite Dermatophagoides pteronyssinus. Biochimica et Biophysica Acta - General Subjects, 1840 (3), 1117–1124. doi:10.1016/j.bbagen.2013.11.017

Lebrun, M., Thelen, N., Thiry, M., Riva, L., Ote, I., Condé, C., Vandevenne, P., Di Valentin, E., BONTEMS, S., & Sadzot-Delvaux, C. (2014). Varicella-zoster virus induces the formation of dynamic nuclear capsid aggregates. Virology, 454-455, 311-27. doi:10.1016/j.virol.2014.02.023

Cloes, M., Renson, T., Johnen, N., Thelen, N., & Thiry, M. (December 2013). Differentiation of Boettcher's cells during postnatal development of rat cochlea. Cell and Tissue Research, 354 (3), 707 716. doi:10.1007/s00441-013-1705-8

Johnen, N., Francart, M.-E., Thelen, N., Cloes, M., & Thiry, M. (2012). Evidence for a partial epithelial-mesenchymal transition in postnatal stages of rat auditory organ morphogenesis. Histochemistry and Cell Biology. doi:10.1007/s00418-012-0969-5

Breuskin, I., Bodson, M., Thelen, N., Thiry, M., Borgs, L., Nguyen, L., Stolt, C., Wegner, M., Lefèbvre, P., & Malgrange, B. (2010). Glial but not neuronal development in the cochleo-vestibular ganglion requires Sox10. Journal of Neurochemistry, 114 (6), 1827-39. doi:10.1111/j.1471-4159.2010.06897.x

Breuskin, I., Bodson, M., Thelen, N., Thiry, M., Borgs, L., Nguyen, L., Lefèbvre, P., & Malgrange, B. (2009). Sox10 promotes the survival of cochlear progenitors during the establishment of the organ of Corti. Developmental Biology, 15 (335), 327-339. doi:10.1016/j.ydbio.2009.09.007

Charlier, C., Lamaye, F., Thelen, N., & Thiry, M. (2009). Ultrastructural detection of nucleic acids within heat shock-induced perichromatin granules of HeLa cells by cytochemical and immunocytological methods. Journal of Structural Biology, 166 (3), 329-36. doi:10.1016/j.jsb.2009.03.002

Thiry, M., Cheutin, T., Lamaye, F., Thelen, N., Meier, U. T., O'Donohue, M.-F., & Ploton, D. (2009). Localization of Nopp140 within mammalian cells during interphase and mitosis. Histochemistry and Cell Biology, 132 (2), 129-40. doi:10.1007/s00418-009-0599-8

Breuskin, I., Bodson, M., Thelen, N., Thiry, M., Nguyen, L., Belachew, S., Lefèbvre, P., & Malgrange, B. (February 2008). Strategies to Regenerate Hair Cells: Identification of Progenitors and Critical Genes. Hearing Research, 236 (1-2), 1-10. doi:10.1016/j.heares.2007.08.007

Thiry, M., Lamaye, F., Thelen, N., Chatron-Colliet, A., Lalun, N., Bobichon, H., & Ploton, D. (2008). A protocol for studying the kinetics of RNA within cultured cells: application to ribosomal RNA. Nature Protocols, 3 (12), 1997-2004. doi:10.1038/nprot.2008.198