Publications and communications of Denis Mottet

Mignon, J., Leyder, T., Mottet, D., Uversky, V. N., & Michaux, C. (14 March 2024). In-depth investigation of the effect of pH on the autofluorescence properties of DPF3b and DPF3a amyloid fibrils. Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy, 313, 124156. doi:10.1016/j.saa.2024.124156

Juniku, B., Mignon, J., Genco, A., Obeid, A. M., Mottet, D., Monari, A., & Michaux, C. (2024). Intrinsic Disorder and Salt-dependent Conformational Changes of the N-terminal TFIP11 Splicing Factor. ACS Omega. doi:10.1101/2024.02.18.580885

Musawi, S., Donnio, L.-M., Zhao, Z., Magnani, C., Rassinoux, P., Binda, O., Huang, J., Jacquier, A., Coudert, L., Lomonte, P., Martinat, C., Schaeffer, L., Mottet, D., Côté, J., Mari, P.-O., & Giglia-Mari, G. (15 November 2023). Nucleolar reorganization after cellular stress is orchestrated by SMN shuttling between nuclear compartments. Nature Communications, 14 (1), 7384. doi:10.1038/s41467-023-42390-4

Leyder, T., Mignon, J., Mottet, D., & Michaux, C. (04 December 2022). Unveiling the Metal-Dependent Aggregation Properties of the C-terminal Region of Amyloidogenic Intrinsically Disordered Protein Isoforms DPF3b and DPF3a. International Journal of Molecular Sciences, 23 (23), 15291. doi:10.3390/ijms232315291

Mignon, J., Mottet, D., Leyder, T., Uversky, V. N., Perpète, E. A., & Michaux, C. (01 October 2022). Structural characterisation of amyloidogenic intrinsically disordered zinc finger protein isoforms DPF3b and DPF3a. International Journal of Biological Macromolecules, 218, 57 - 71. doi:10.1016/j.ijbiomac.2022.07.102

Duchemin, A., O'Grady, T., Hanache, S., Mereau, A., Thiry, M., Wacheul, L., Michaux, C., Perpète, E., Hervouet, E., Peixoto, P., Ernst, F., Audic, Y., Dequiedt, F., Lafontaine, D., & Mottet, D. (2021). DHX15-independent roles for TFIP11 in U6 snRNA modification, U4/U6.U5 tri-snRNP assembly and pre-mRNA splicing fidelity. Nature Communications. doi:10.1038/s41467-021-26932-2

Hanache, S., Duchemin, A., O'Grady, T., Mereau, A., Thiry, M., Wacheul, L., Michaux, C., Perpète, E., Hervouet, E., Peixoto, P., Ernst, F., Audic, Y., Dequiedt, F., Lafontaine, D., & Mottet, D. (17 October 2021). DHX15-independent roles for TFIP11 in U6 snRNA modi!cation, U4/U6.U5 tri-snRNP assembly and pre-mRNA splicing fidelity [Poster presentation]. EMBL.

Warnon, C., Bouhjar, K., Ninane, N., Verhoyen, M., Fattaccioli, A., Fransolet, M., Lambert de Rouvroit, C., Poumay, Y., Piel, G., Mottet, D., & Debacq-Chainiaux, F. (12 July 2021). HDAC2 and 7 down-regulation induces senescence in dermal fibroblasts. Aging, 13, 17978-18005. doi:10.18632/aging.203304

Hanache, S., Duchemin, A., Peixoto, P., Hervouet, E., Dequiedt, F., & Mottet, D. (01 February 2019). Phospho-Dependant Regulation Of TFIP11 Splicing Factor [Poster presentation]. BACR.

Veloso, A., Martin, M., Bruyr, J., O'Grady, T., Deroanne, C., Mottet, D., Twizere, J.-C., Cherrier, T.* , & Dequiedt, F.*. (2019). Dephosphorylation of HDAC4 by PP2A-Bdelta unravels a new role for the HDAC4/MEF2 axis in myoblast fusion. Cell death & disease, 10 (7), 512. doi:10.1038/s41419-019-1743-6
* These authors have contributed equally to this work.

Lechanteur, A., Sanna, V., Duchemin, A., Evrard, B., Mottet, D., & Piel, G. (August 2018). Cationic Liposomes Carrying siRNA: Impact of Lipid Composition on Physicochemical Properties, Cytotoxicity and Endosomal Escape [Paper presentation]. 12th International Conference and Workshop on Biological barriers, Saarbruck, Germany.

Hendrick, E., Peixoto, P., Blomme, A., Polese, C., Matheus, N., Cimino, J., Frère, A., Mouithys-Mickalad, A., Serteyn, D., Bettendorff, L., Elmoualij, B., De Tullio, P., Eppe, G., Dequiedt, F., Castronovo, V., & Mottet, D. (2017). Metabolic inhibitors accentuate the anti-tumoral effect of HDAC5 inhibition. Oncogene. doi:10.1038/onc.2017.103

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., Adhihetty, P. J., Adler, S. G., Agam, G., Agarwal, R., Aghi, M. K., Agnello, M., Agostinis, P., Aguilar, P. V., Aguirre-Ghiso, J., ... Choubey, V. (2016). Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy, 12 (1), 1-222. doi:10.1080/15548627.2015.1100356

Polese, C., & Mottet, D. (01 September 2014). Inhiber HDAC5 : un outil pour couper court à l’immortalité des cellules cancéreuses. MS. Medecine Sciences, 30 (numero 8-9), 730-732. doi:10.1051/medsci/20143008005

Frère, A., Tempelaar, S., Peixoto, P., Peulen, O., Evrard, B., Dubois, P., Mespouille, L., Mottet, D., & Piel, G. (28 August 2014). Polyplex based on polycarbonate polymesr for an efficient delivery of an anti-angiogenic siRNA [Paper presentation]. Translational Nanomedicine, Angers, France.

Frère, A., Kawalec, M., Tempelaar, S., Peixoto, P., Peulen, O., Evrard, B., Dubois, P., Mespouille, L., Mottet, D., & Piel, G. (2014). Polyplex Based On Polycarbonate Polymers For An Efficient Delivery Of An Anti-Angiogenic siRNA [Poster presentation]. 3rd NanoFar Autumn School, Brussels, Belgium.

Frère, A., Krier, F., Evrard, B., Mottet, D., & Piel, G. (2014). Polyplex Based On Polycarbonate Polymers For An Efficient Delivery Of An Anti-Angiogenic siRNA [Poster presentation]. 2014 AAPS Annual Meeting and Exposition, San Diego, United States.

Frère, A., Peixoto, P., Mottet, D., & Piel, G. (17 October 2013). Polyplexes based on polycarbonate polymers and siRNA against HDAC7 for a targeted anti-angiogenic therapy [Paper presentation]. 17th forum of Pharmaceutical Sciences, Spa, Belgium.

Peulen, O.* , Gonzalez, A.* , Peixoto, P., Turtoi, A., Mottet, D., Delvenne, P., & Castronovo, V. (11 September 2013). The Anti-Tumor Effect of HDAC Inhibition in a Human Pancreas Cancer Model Is Significantly Improved by the Simultaneous Inhibition of Cyclooxygenase 2. PLoS ONE, 8 (9), 75102. doi:10.1371/journal.pone.0075102
* These authors have contributed equally to this work.

Novo, C. L., Polese, C., Matheus, N., Decottignies, A., Londono-Vallejo, A., Castronovo, V., & Mottet, D. (September 2013). A new role for histone deacetylase 5 in the maintenance of long telomeres. FASEB Journal, 27. doi:10.1096/fj.12-224204

Frère, A., Kawalec, M., Collard, L., Matheus, N., Peixoto, P., Evrard, B., Dubois, P., Mespouille, L., Mottet, D., & Piel, G. (22 October 2012). Characterization and transfection experiments of polyplexes targeting HDAC7 [Poster presentation]. NanoFar Autumn School, Angers, France.

Turtoi, A., Mottet, D., Matheus, N., Dumont, B., Peixoto, P., Hennequière, V., Deroanne, C., Colige, A., De Pauw, E., Bellahcene, A., & Castronovo, V. (2012). The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells. Angiogenesis. doi:10.1007/s10456-012-9279-8