Francotte, P., Bay, Y., Goffin, E., Colson, T., Lesenfants, C., Dorosz, J., Laulumaa, S., Fraikin, P., De Tullio, P., Beaufour, C., Botez, I., Pickering, D., Frydenvang, K., Danober, L., Skov Kristensen, A., Sandholm Kastrup, J., & Pirotte, B. (09 December 2023). Exploring thienothiadiazine dioxides as isosteric analogues of benzo-and pyridothiadiazine dioxides in the search of new AMPA and kainate receptor positive allosteric modulators. European Journal of Medicinal Chemistry, 264, 116036. doi:10.1016/j.ejmech.2023.116036 |
Lesenfants, C., Goffin, E., Pirotte, B., Dammicco, S., & Francotte, P. (02 February 2022). Contribution to the synthesis of positive allosteric modulators of AMPA receptors for potential use in the early diagnosis of neurodegenerative diseases [Poster presentation]. CIRM Day, Liège, Belgium. |
Conlon, T., John-Schuster, G., Heide, D., Pfister, D., Lehmann, M., Hu, Y., Ertuz, Z., Lopez, M., Ansari, M., Strunz, M., Mayr, C., Cimineiri, C., Costa, R., Kohlhepp, M. S., Guillot, A., Günes, G., Jeridi, A., Funk, M., Beroshvili, G., ... Yildirim, A. Ö. (2020). Inhibition of LTβR-signalling activates Wnt-induced regeneration in lung. Nature. doi:10.1038/s41586-020-2882-8 |
Goffin, E., Jacques, N., Musumeci, L., Nchimi Longang, A., Oury, C., Lancellotti, P., & Pirotte, B. (2020). Synthesis of ticagrelor analogues belonging to 1,2,3-triazolo[4,5-d]pyrimidines and study of their antiplatelet and antibacterial activity. European Journal of Medicinal Chemistry, 208, 112767. doi:10.1016/j.ejmech.2020.112767 |
Lancellotti, P., Musumeci, L., Jacques, N., Servais, L., Goffin, E., Pirotte, B., & Oury, C. (2019). Antibacterial Activity of Ticagrelor in Conventional Antiplatelet Dosages Against Antibiotic-Resistant Gram-Positive Bacteria. JAMA Cardiology. doi:10.1001/jamacardio.2019.1189 |
Schnekenburger, M., Goffin, E., Lee, J.-Y., Jang, J. Y., Mazumder, A., Ji, S., Rogister, B., Bouider, N., Lefranc, F., Miklos, W., Mathieu, V., De Tullio, P., Kim, K.-W., Dicato, M., Berger, W., Han, B., Kiss, R., Pirotte, B., & Diederich, M. (08 June 2017). Discovery and Characterization of R/S-N-3-Cyanophenyl-N'-(6-tert-butoxycarbonylamino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)urea, a New Histone Deacetylase Class III Inhibitor Exerting Antiproliferative Activity against Cancer Cell Lines. Journal of Medicinal Chemistry, 60 (11), 4714-4733. doi:10.1021/acs.jmedchem.7b00533 |
Drapier, T., Geubelle, P., Bouckaert, C., Goffin, E., Dilly, S., Hanson, J., Pochet, L., Kastrup, J. S., Francotte, P., & Pirotte, B. (26 May 2016). DESIGN OF HIGH-AFFINITY LIGANDS FOR THE BENZOTHIADIAZINE ALLOSTERIC BINDING SITE OF THE AMPA RECEPTORS [Poster presentation]. JFB 2016 : 30èmes Journées Franco-Belges de Pharmacochimie 25-27 May 2016 Amboise (France), Amboise, France. |
Goffin, E., Lamoral-Theys, D., Tajeddine, N., De Tullio, P., Mondin, L., Lefranc, F., Gailly, P., ROGISTER, B., Kiss, R., & Pirotte, B. (2012). N-Aryl-N'-(chroman-4-yl)ureas and thioureas display in vitro anticancer activity and selectivity on apoptosis-resistant glioblastoma cells: screening, synthesis of simplified derivatives, and structure-activity relationship analysis. European Journal of Medicinal Chemistry, 54, 834-44. doi:10.1016/j.ejmech.2012.06.050 |
Ziemons, E., Goffin, E., Lejeune, R., Proença da Cunha, A. P., Angenot, L., & Thunus, L. (January 2005). Supercritical carbon dioxide extraction of tagitinin C from Tithonia diversifolia. Journal of Supercritical Fluids, 33 (1), 53-59. doi:10.1016/j.supflu.2004.04.001 |
Ziemons, E., Goffin, E., Lejeune, R., Angenot, L., & Thunus, L. (06 February 2004). FT-IR measurement of tagitinin C after solvent extraction from Tithonia diversifolia. Talanta, 62 (2), 383-387. doi:10.1016/j.talanta.2003.08.007 |
Philippe, G., Angenot, L., De Mol, P., Goffin, E., Tits, M., & Frederich, M. (February 2003). In vitro screening of Strychnos species for antiplasmodial activity [Poster presentation]. 27th Landelijk Overleg Farmacognosie (LOF) Symposium, Antwerpen, Belgium. |
Ziemons, E., Goffin, E., Lejeune, R., Angenot, L., & Thunus, L. (2003). Supercritical fluid extraction of tagitinin C from Tithonia diversifolia: Comparison of extraction yield and selectivity between supercritical fluid and classical methods of extraction [Paper presentation]. 6th International Symposium on Supercritical fluids, Versailles, France. |
Ziemons, E., Goffin, E., Lejeune, R., Angenot, L., & Thunus, L. (2003). Comparison of extraction yield and selectivity between supercritical fluid and classical methods of tagitinin C extraction [Paper presentation]. 11th Forum of Pharmaceutical Sciences, Spa, Belgium. |
Goffin, E., Frederich, M., Philippe, G., Ziemons, E., De Mol, P., Proença da Cunha, A., Tits, M., & Angenot, L. (September 2001). In vitro antiplasmodial activity of Tithonia diversifolia and identification of its active constituent: tagitinin C [Poster presentation]. Lead Compounds from Higher Plants, Lausanne, Switzerland. |
Ziemons, E., Goffin, E., Angenot, L., & Thunus, L. (2001). Extraction of sesquiterpenic lactones with CO2 supercritical fluid and quantification of the extract by FTIR spectroscopy [Paper presentation]. 10th Forum of Pharmaceutical Sciences, Montréal, Canada. |