Publications and communications of Jean Defourny

Defourny, J. (2022). Considering gene therapy to protect from X‐linked deafness DFNX2 and associated neurodevelopmental disorders. Ibrain. doi:10.1002/ibra.12068

Defourny, J., & Thiry, M. (2022). Recent insights into gap junction biogenesis in the cochlea. Developmental Dynamics. doi:10.1002/dvdy.538

Saume, A., Thiry, M., & Defourny, J. (2021). LDLR expression in the cochlea suggests a role in endolymph homeostasis and cochlear amplification. Hearing Research. doi:10.1016/j.heares.2021.108311

Thelen, N., Defourny, J., Lafontaine, D., & Thiry, M. (2021). Visualization of chromatin in the yeast nucleus and nucleolus using hyperosmotic shock. International Journal of Molecular Sciences. doi:10.3390/ijms22031132

Defourny, J., Audouard, C., Davy, A., & Thiry, M. (2021). Efnb2 haploinsufficiency induces early gap junction plaque disassembly and endocytosis in the cochlea. Brain Research Bulletin. doi:10.1016/j.brainresbull.2021.06.008

Petit, C., Delmaghani, S., Defourny, J., & Aghaie, A. (28 May 2020). Combination of pejvakin and LC3B for treating hearing losses.

Defourny, J., & Thiry, M. (2020). Tricellular adherens junctions provide a cell surface delivery platform for connexin 26/30 oligomers in the cochlea. Hearing Research, 400, 108137. doi:10.1016/j.heares.2020.108137

Bartholomé, O., Franck, C., Piscicelli, P., Lalun, N., Defourny, J., Renauld, J., Thelen, N., Lamaye, F., Ploton, D., & Thiry, M. (September 2019). Relationships between the structural and functional organization of the turtle cell nucleolus. Journal of Structural Biology, 208 (3), 107398. doi:10.1016/j.jsb.2019.09.015

Defourny, J. (2019). Eph/ephrin signalling in the development and function of the mammalian cochlea. Developmental Biology. doi:10.1016/j.ydbio.2019.02.004

Defourny, J., Aghaie, A., Perfettini, I., Avan, P., Delmaghani, S., & Petit, C. (2019). Pejvakin-mediated pexophagy protects auditory hair cells against noise-induced damage. Proceedings of the National Academy of Sciences of the United States of America. doi:10.1073/pnas.1821844116

Defourny, J., Peuckert, C., Kullander, K., & Malgrange, B. (2019). EphA4-ADAM10 Interplay Patterns the Cochlear Sensory Epithelium through Local Disruption of Adherens Junctions. iScience, 11, 246-257. doi:10.1016/j.isci.2018.12.017

Defourny, J., Thelen, N., & Thiry, M. (2019). Cochlear connexin 30 homomeric and heteromeric channels exhibit distinct assembly mechanisms. Mechanisms of Development. doi:10.1016/j.mod.2018.10.001

Defourny, J., Thelen, N., & Thiry, M. (2019). Actin-independent trafficking of cochlear connexin 26 to non-lipid raft gap junction plaques. Hearing Research. doi:10.1016/j.heares.2019.01.020

Petit, C., Avan, P., Delmaghani, S., Defourny, J., Aghaie, A., Safieddine, S., & Emptoz, A. (25 August 2016). Prevention and/or treatment of hearing loss or impairment.

Delmaghani, S., Defourny, J., Aghaie, A., Beurg, M., Dulon, D., Thelen, N., Perfettini, I., Zelles, T., Aller, M., Meyer, A., Emptoz, A., Giraudet, F., Leibovici, M., Dartevelle, S., Soubigou, G., Thiry, M., Vizi, E. S., Safieddine, S., Hardelin, J.-P., ... Petit, C. (November 2015). Hypervulnerability to Sound Exposure through Impaired Adaptive Proliferation of Peroxisomes. Cell, 163 (4), 894-906. doi:10.1016/j.cell.2015.10.023

Defourny, J., Mateo Sanchez, S., Schoonaert, L., Robberecht, W., Davy, A., Nguyen, L., & Malgrange, B. (2015). Cochlear supporting cell transdifferentiation and integration into hair cell layers by inhibition of ephrin-B2 signalling. Nature Communications. doi:10.1038/ncomms8017

Defourny, J., Poirrier, A.-L., Lallemend, F., Mateo Sanchez, S., Neef, J., Vanderhaeghen, P., Soriano, E., Peuckert, C., Kullander, K., Fritzsch, B., Nguyen, L., Moonen, G., Moser, T., & Malgrange, B. (2013). Ephrin-A5/EphA4 signalling controls specific afferent targeting to cochlear hair cells. Nature Communications, 4, 1438. doi:10.1038/ncomms2445