Van Laethem, T., Kumari, P., Boulanger, B., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (28 November 2022). User-Driven Strategy for In Silico Screening of Reversed-Phase Liquid Chromatography Conditions for Known Pharmaceutical-Related Small Molecules. Molecules, 27 (23), 8306. doi:10.3390/molecules27238306 |
Hubert, C., Lebrun, P., Boulanger, B., & Hubert, P. (11 May 2017). Cycle de vie des méthodes, vers une maîtrise intégrée des performances quantitatives [Paper presentation]. AFSEP - Comment garantir un résultat quantitatif ?, Lyon, France. |
Lebrun, P., Giacoletti, K., Scherder, T., Rozet, E., & Boulanger, B. (2015). A quality by design approach for longitudinal quality attributes. Journal of Biopharmaceutical Statistics, 25, 1-13. doi:10.1080/10543406.2014.979197 |
Rozet, E., Lebrun, P., Michiels, J.-F., Sondag, P., Scherder, T., & Boulanger, B. (2015). Analytical Procedure Validation and the Quality by Design Paradigm. Journal of Biopharmaceutical Statistics, 25, 1-9. doi:10.1080/10543406.2014.971176 |
Lebrun, P., Boulanger, B., Debrus, B., Lambert, P., & Hubert, P. (2013). A Bayesian Design Space for analytical methods based on multivariate models and predictions. Journal of Biopharmaceutical Statistics, 23, 1330–1351. doi:10.1080/10543406.2013.834922 |
Dispas, A., Lebrun, P., Mbinze Kindenge, J., Debrus, B., Mavar Tayer Mbay, J., Boulanger, B., Marini Djang'Eing'A, R., & Hubert, P. (December 2011). Application d'une nouvelle méthode de développement de méthodes chromatographiques pour lutter contre la contrefaçon des médicaments anti-inflammatoires [Paper presentation]. Chimiométrie 2011, Marseille, France. |
Rozet, E., Marini Djang'Eing'A, R., Lebrun, P., Ziemons, E., Boulanger, B., & Hubert, P. (September 2011). A BAYESIAN PREDICTIVE PROBABILITY CRITERION TO ASSESS ANALYTICAL METHODS VALIDITY [Poster presentation]. Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy. |
Rozet, E., Lebrun, P., Boulanger, B., Ziemons, E., & Hubert, P. (02 December 2010). Evaluating analytical results reliability using a Bayesian probability criterion [Poster presentation]. Congrès Chimimétrie 2010, Paris, France. |
Lebrun, P., Lambert, P., Debrus, B., Hubert, P., Marini Djang'Eing'A, R., Moonen, F., & Boulanger, B. (December 2010). Developing and optimizing analytical chromatographic method in a Quality by Design environment. Bayesian multi-criteria risk-based Design Space to guarantee future quality [Poster presentation]. Chimiométrie 2010, Paris, France. |
Hubert, P., Ziemons, E., Mantanus, J., Lebrun, P., Boulanger, B., & Rozet, E. (October 2010). RISK MANAGMENT IN THE VALIDATION OF ANALYTICAL METHODS [Paper presentation]. CNFR 2010 Congress, Targu-Mures, Romania. |
Nistor, I., Debrus, B., Lebrun, P., Lecomte, F., Cao, M., Frederich, M., Angenot, L., Boulanger, B., Oprean, R., & Hubert, P. (September 2010). Application of experimental design and design for the separation of compounds extracted from the leaves of Strychnos Usambarensis [Poster presentation]. Drug analysis 2010, Antwerpen, Belgium. |
Nistor, I., Debrus, B., Lebrun, P., Lecomte, F., Martine, C., Frederich, M., Angenot, L., Boulanger, B., Oprean, R., & Hubert, P. (26 January 2010). Optimisation de la séparation des alcaloïdes extraits des feuilles de Strychnos usambarensis au moyen du design space [Paper presentation]. Assemblée générale du CIRM et forum des jeunes chercheurs, Liège, Belgium. |
Mbinze Kindenge, J., Marini Djang'Eing'A, R., Debrus, B., Lebrun, P., Lecomte, F., Boulanger, B., & Hubert, P. (December 2009). Développement d’une méthode pour la séparation de 19 antipaludéens par HPLC au moyen de la planification expérimentale et du Design Space [Poster presentation]. 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages (SEP'09), Marseille, France. |
Nistor, I., Debrus, B., Lebrun, P., Lecomte, F., Cao, M., Frederich, M., Angenot, L., Boulanger, B., Oprean, R., & Hubert, P. (December 2009). Application de la planification expérimentale et du design space pour la séparation des composés extraits des feuilles de Strychnos usambarensis [Poster presentation]. 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages (SEP'09), Marseille, France. |
Nistor, I., Debrus, B., Lebrun, P., Rozet, E., Ceccato, A., Caliaro, G., Oprean, R., Boulanger, B., & Hubert, P. (27 April 2009). Nouvelle méthodologie pour le développement automatisé de méthodes analytiques en chromatographie liquide pour l'analyse de mélanges de composés inconnus [Paper presentation]. Assemblée générale du CIRM et forum des jeunes chercheurs, Liège, Belgium. |
Rozet, E., Boulanger, B., Rudaz, S., Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2009). Universal applicability of Total Error for the validation of bioanalytical methods [Paper presentation]. 4èmes JOURNEES INTERNATIONALES de toxicologie, liege, Belgium. |
Rozet, E., Boulanger, B., Rudaz S, Marini Djang'Eing'A, R., Ziemons, E., & Hubert, P. (2009). Total Error for the Valildation of Bioanalytical methods. Annales de Toxicologie Analytique, 21 (S1), 35. |
Debrus, B., Lebrun, P., Ceccato, A., Caliaro, G., Rozet, E., Rupérez, J., Barbas, C., Boulanger, B., & Hubert, P. (July 2008). Chromatographic separation of a pharmaceutical formulation using Design of Experiment and Design Space [Poster presentation]. 11th conference on Chemometrics in Analytical Chemistry (CAC'2008), Montpellier, France. |
Debrus, B., Lebrun, P., Ceccato, A., Caliaro, G., Jupérez, J., Barbas, C., Boulanger, B., & Hubert, P. (June 2008). Usefulness of design space for the optimization of chromatographic separations [Paper presentation]. 19th International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2008), Gdansk, Poland. |
Rozet, E., Dewe, W., Boulanger, B., Ziemons, E., Hubert, C., Moonen, F., & Hubert, P. (2008). Simultaneous improvement of the predictive character of the validation data and estimation of measurement uncertainty [Paper presentation]. Agrostat, Louvain-la-Neuve, Belgium. |
Lebrun, P., Debrus, B., Boulanger, B., Caliaro, G., Ceccato, A., & Hubert, P. (June 2007). Numerical separation in HPLC-UV-DAD with Independent Component Analysis (ICA) using high order statistics for the automated identification of peaks [Poster presentation]. HPLC 2007, Gent, Belgium. |
Marini Djang'Eing'A, R., Servais, A.-C., Rozet, E., Chiap, P., Boulanger, B., Rudaz, S., Crommen, J., Hubert, P., & Fillet, M. (June 2007). Enantiomeric purity testing of S-timolol by non-aqueous CE using heptakis(2,3-di-O-methyl-6-O-Sulfo)-β-cyclodextrin as chiral additive – Validation using the accuracy profile strategy and estimation of uncertainty [Poster presentation]. 31st International Symposium on HPLC and Related techniques, Gand, Belgium. |
Debrus, B., Lebrun, P., Boulanger, B., Dewé, W., Ceccato, A., & Hubert, P. (20 March 2007). Séparation numérique et quantification automatique de pics en CLHP-UV grâce à l’utilisation de l’analyse en composantes indépendantes (ICA) [Paper presentation]. SEP 2007, Grenoble, France. |
Debrus, B., Lebrun, P., Boulanger, B., Dewé, W., Ceccato, A., & Hubert, P. (20 March 2007). Evaluation d'une nouvelle méthode pour le développement entièrement automatisé de méthodes analytiques en chromatographie liquide [Poster presentation]. SEP 2007, Grenoble, France. |
Hubert, C., Rozet, E., Ceccato, A., Dewé, W., Ziemons, E., Moonen, F., Michail, K., Wintersteiger, R., Streel, B., Boulanger, B., & Hubert, P. (March 2007). Validation versus routine : Evaluation de l'aspect prédictif de l'intervalle de tolérance [Poster presentation]. 7ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages, Grenoble, France. |
Boulanger, B., Dewé, W., Ceccato, A., Debrus, B., Lebrun, P., & Hubert, P. (December 2006). Utilisation de l’Analyse en Composantes Indépendantes (ICA) pour la séparation numérique des pics et la quantification automatique en CLHP-UV [Paper presentation]. Chimiométrie 2006, Paris, France. |
Lebrun, P., Boulanger, B., Hubert, P., Debrus, B., & Govaerts, B. (December 2006). Statistical Models and Multi-Criteria Optimization Techniques in Chromatography [Paper presentation]. Chimiométrie 2006, Paris, France. |
Marini Djang'Eing'A, R., Chiap, P., Boulanger, B., Rudaz, S., Rozet, E., Crommen, J., & Hubert, P. (November 2006). Comparaison de trois approches pour l'estimation de l'incertitude [Paper presentation]. 3ème journée internationale de toxicologie hospitalière, Liège, Belgium. |
Lecomte, F., Aerts, J., Plenevaux, A., Lignon, S., Haber, G., Boulanger, B., Chiap, P., Luxen, A., & Hubert, P. (September 2006). EVALUATION OF MOLECULARLY IMPRINTED POLYMERS BY MEANS OF EXPERIMENTAL DESIGN PRIOR TO THE DETERMINATION OF p-[18F]MPPF IN PLASMA [Poster presentation]. MIP2006 - Fourth International Workshop on Molecularly Imprinted Polymers, Cardiff, United Kingdom. |
Hubert, C., Rozet, E., Boulanger, B., Dewé, W., Breuer, A., Collard, L., Evrard, B., & Hubert, P. (May 2006). Validation of a LC method for the determination of levonorgestrel released from a polymeric matrix. A two days protocol [Poster presentation]. Drug Analysis 2006, Namur, Belgium. |
Marini Djang'Eing'A, R., Rozet, E., Ziemons, E., Chiap, P., Boulanger, B., Rudaz, S., Servais, A.-C., Fillet, M., Crommen, J., & Hubert, P. (May 2006). COMPARISON OF THREE DIFFERENT APPROACHES FOR UNCERTAINTY ESTIMATION CONSIDERING LC AND CE METHODS [Paper presentation]. A joint meeting of two distinguished series: the 8th International Symposium on Drug Analysis and the 17th International Symposium on Pharmaceutical and Biomedical Analysis, Namur, Belgium. |
Lecomte, F., Boulanger, B., Hall, A. J., Sellergren, B., Crommen, J., Chiap, P., & Hubert, P. (March 2006). Développement d’une méthode de dosage automatisé du méthotrexate dans le plasma humain par couplage direct à la chromatographie liquide de l’extraction sur phase solide à empreintes moléculaires [Poster presentation]. Forum LABO & Forum BIOTECH 2006, Paris, France. |
Rozet, E., Boulanger, B., Dewe, W., Chiap, P., Moonen, F., Govaerts, B., Crommen, J., & Hubert, P. (2006). GERER LE RISQUE LORS DE LA VALIDATION DES METHODES ANALYTIQUES : APPLICATION A LA DETERMINATION D’IMPURETES [Paper presentation]. Congrès des Sciences Analytiques, Marrakech, Morocco. |
Lecomte, F., Boulanger, B., Hall, A. J., Sellergren, B., Rozet, E., Crommen, J., Chiap, P., & Hubert, P. (September 2005). OPTIMIZATION OF MOLECULARLY IMPRINTED SOLID-PHASE EXTRACTION BY MEANS OF EXPERIMENTAL DESIGN PRIOR TO THE DETERMINATION OF METHOTREXATE IN HUMAN PLASMA [Poster presentation]. RDPA 2005 - 11th International Meeting on Recent Developments in Pharmaceutical Analysis, Rimini, Italy. |
Fotsing, L., Boulanger, B., Chiap, P., Fillet, M., Hubert, P., & Crommen, J. (2000). Multivariate optimization approach for the separation of water-soluble vitamins and related compounds by capillary electrophoresis. Biomedical Chromatography: BMC, 14 (1), 10-1. doi:10.1002/(SICI)1099-0801(200002)14:1<10::AID-BMC947>3.0.CO;2-8 |
Boulanger, B., Ingebos, A.-M., Lahak, M., Machado, A., & Richelle, M. (1987). Variabilité comportementale et conditionnement operant chez l'animal: Revue critique. Année Psychologique, 87, 417-734. |