Publications and communications of Christophe Deroanne

Garbacki, N., Willems, J., Neutelings, T., Lambert, C., Deroanne, C., Adrian, A., Franz, M., Maurer, M., De Gieter, P., Nusgens, B., & Colige, A. (16 December 2023). Microgravity triggers ferroptosis and accelerates senescence in the MG-63 cell model of osteoblastic cells. NPJ Microgravity, 9 (1), 91. doi:10.1038/s41526-023-00339-3

Tripathi, M., Colige, A., & Deroanne, C. (16 February 2023). The Dual Function of RhoGDI2 in Immunity and Cancer. International Journal of Molecular Sciences, 24 (4), 4015. doi:10.3390/ijms24044015

Dupont, L.* , Noël, A.* , Colige, A.* , Joannes, L. (Other coll.), Morfoisse, F. (Other coll.), BLACHER, S. (Other coll.), Monseur, C. (Other coll.), & Deroanne, C. (Other coll.). (2022). ADAMTS2 and ADAMTS14 substitute ADAMTS3 in adults for proVEGFC activation and lymphatic homeostasis. JCI Insight. doi:10.1172/jci.insight.151509

Brohée, L., Cremer, J., Colige, A., & Deroanne, C. (23 April 2021). Lipin-1, a Versatile Regulator of Lipid Homeostasis, Is a Potential Target for Fighting Cancer. International Journal of Molecular Sciences, 22 (9), 4419. doi:10.3390/ijms22094419

Blomme, B.* , Deroanne, C.* , Hulin, A., Lambert, C., Defraigne, J.-O., Nusgens, B., Radermecker, M., & Colige, A. (20 August 2019). Mechanical strain induces a pro-fibrotic phenotype in human mitral valvular interstitial cells through RhoC/ROCK/MRTF-A and Erk1/2 signaling pathways. Journal of Molecular and Cellular Cardiology, 135, 149-159. doi:10.1016/j.yjmcc.2019.08.008

Veloso, A., Martin, M., Bruyr, J., O'Grady, T., Deroanne, C., Mottet, D., Twizere, J.-C., Cherrier, T.* , & Dequiedt, F.*. (2019). Dephosphorylation of HDAC4 by PP2A-Bdelta unravels a new role for the HDAC4/MEF2 axis in myoblast fusion. Cell death & disease, 10 (7), 512. doi:10.1038/s41419-019-1743-6

Brohée, L., Peulen, O., Nusgens, B., Castronovo, V., Thiry, M., Colige, A., & Deroanne, C. (04 May 2018). Propranolol sensitizes prostate cancer cells to glucose metabolism inhibition and prevents cancer progression. Scientific Reports, 8 (1), 7050. doi:10.1038/s41598-018-25340-9

Rademaker, G., Hennequière, V., Nokin, M.-J., LOVINFOSSE, P., Durieux, F., GOFFLOT, S., Bellier, J., Costanza, B., Herfs, M., Peiffer, R., Bettendorff, L., Deroanne, C., Thiry, M., Delvenne, P., Hustinx, R., Bellahcene, A., Castronovo, V., & Peulen, O. (April 2018). Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness. Oncogene, 37 ((32)), 4398-4412. doi:10.1038/s41388-018-0287-z

Hendricks, C., Dubail, J., Brohée, L., Delforge, Y., Colige, A.* , & Deroanne, C.*. (2016). A Novel Physiological Glycosaminoglycan-Deficient Splice Variant of Neuropilin-1 Is Anti-Tumorigenic In Vitro and In Vivo. PLoS ONE. doi:10.1371/journal.pone.0165153

Truong, A., Yip, C., PAYE, A., Blacher, S., Munaut, C., Deroanne, C., Noël, A., & Sounni, N. E. (February 2016). Dynamics of Internalization and Recycling of the Pro-Metastatic Membrane Type 4-Matrix Metalloproteinase (MT4-MMP) in Breast Cancer Cells. FEBS Journal, 283 (4), 704-22. doi:10.1111/febs.13625

Brohée, L., Demine, S., Willems, J., Arnould Thierry, Colige, A., & Deroanne, C. (10 May 2015). Lipin-1 regulates cancer cell phenotype and is a potential target to potentiate rapamycin treatment. Oncotarget, 6 (13), 11264-11280. doi:10.18632/oncotarget.3595

Hendricks, C., Janssen, L., Delcombel, R., Dubail, J., Deroanne, C., & Colige, A. (22 April 2015). Study of a new splice variant of Neuropilin-1: antagonistic functions in the regulation of cancer progression? [Poster presentation]. AACR Annual Meeting 2015, Philadelphie, United States - Pennsylvania.

Louis, F., Deroanne, C., Nusgens, B., Vico, L., & Guignandon, A. (2015). RhoGTPases as Key players in mammalian cell adaptation to microgravity. BioMed Research International. doi:10.1155/2015/747693

Renoux, V., Bisig, B., Langers, I., Bastin, R., Thiry, M., Deroanne, C., Delvenne, P., & Jacobs, N. (May 2013). Human papillomavirus entry into NK cells requires CD16 expression and triggers cytotoxic activity and cytokine secretion [Poster presentation]. Gordon Conference Virus & Cell, Lucca, Italy.

Renoux, V., Langers, I., Dortu, E., Bisig, B., Thiry, M., Deroanne, C., Boniver, J., Delvenne, P., & Jacobs, N. (28 January 2013). Human papillomavirus entry into NK cells requires CD16 expression and triggers cytotoxic activity and cytokine secretion [Paper presentation]. GIGA-Day, Liège, Belgium.

Hulin, A., Deroanne, C., Lambert, C., Defraigne, J.-O., Nusgens, B., RADERMECKER, M., & Colige, A. (2013). Emerging pathogenic mechanisms in human myxomatous mitral valve: lessons from past and novel data. Cardiovascular Pathology, 22 (4), 245-250. doi:10.1016/j.carpath.2012.11.001

Stultiens, A., HO, T. T. G., Nusgens, B., Colige, A., & Deroanne, C. (January 2012). Rho proteins crosstalk via RhoGDIalpha. Communicative and Integrative Biology, 5 (1), 99-101.

Turtoi, A., Mottet, D., Matheus, N., Dumont, B., Peixoto, P., Hennequière, V., Deroanne, C., Colige, A., De Pauw, E., Bellahcene, A., & Castronovo, V. (2012). The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells. Angiogenesis. doi:10.1007/s10456-012-9279-8

Renoux, V., Bisig, B., Langers, I., Dortu, E., Clemenceau, B., Thiry, M., Deroanne, C., Colige, A., Boniver, J., Delvenne, P., & Jacobs, N. (November 2011). Human papillomavirus entry into NK cells requires CD16 expression and triggers cytotoxic activity and cytokine secretion. European Journal of Immunology, 41 (11), 3240-3252. doi:10.1002/eji.201141693

Renoux, V., Langers, I., Clémenceau, B., Thiry, M., Bisig, B., Deroanne, C., Dortu, E., Boniver, J., Delvenne, P., & Jacobs, N. (13 September 2011). Macropinocytosis of human papillomaviruses in natural killer cells via CD16 induces cytotoxic granule exocytosis and cytokine secretion [Poster presentation]. IUMS International Congress of Virology, Sapporo, Japan.

Garbacki, N., Di Valentin, E., Huynh-Thu, V. A., Geurts, P., Irrthum, A., Crahay, C., Arnould, T., Deroanne, C., Piette, J., Cataldo, D., & Colige, A. (2011). MicroRNAs Profiling in Murine Models of Acute and Chronic Asthma: A Relationship with mRNAs Targets. PLoS ONE. doi:10.1371/journal.pone.0016509

Ho, T. T. G., Stultiens, A., Dubail, J., Lapiere, C. M., Nusgens, B., Colige, A., & Deroanne, C. (2011). RhoGDI alpha-dependent balance between RhoA and RhoC is a key regulator of cancer cell tumorigenesis. Molecular Biology of the Cell, 22 (17), 3263-75. doi:10.1091/mbc.E11-01-0020

Jacobs, N., Renoux, V., Bisig, B., Langers, I., Dortu, E., Clémenceau, B., Thiry, M., Deroanne, C., Boniver, J., & Delvenne, P. (2011). HPV triggers NK cell cytotoxic activity and cytokine secretion [Paper presentation]. 27th International Papillomavirus Conference, Berlin, Germany.

Sabatel, C., Malvaux, L., Bovy, N., Deroanne, C., LAMBERT, V., Alvarez Gonzalez, M.-L., Colige, A., Rakic, J.-M., Noël, A., Martial, J., & Struman, I. (2011). MicroRNA-21 Exhibits Antiangiogenic Function by Targeting RhoB Expression in Endothelial Cells. PLoS ONE, 6 (2), 16979. doi:10.1371/journal.pone.0016979

Dubail, J., Kesteloot, F., Deroanne, C., Motte, P., Lambert, V., Rakic, J.-M., Lapiere, C., Nusgens, B., & Colige, A. (2010). ADAMTS-2 functions as anti-angiogenic and anti-tumoral molecule independently of its catalytic activity. Cellular and Molecular Life Sciences. doi:10.1007/s00018-010-0431-6

Henno, A., Blacher, S., Lambert, C., Deroanne, C., Noël, A., Lapière, C., de LA BRASSINNE, M., Nusgens, B., & Colige, A. (2010). Histological and transcriptional study of angiogenesis and lymphangiogenesis in uninvolved skin, acute pinpoint lesions and established psoriasis plaques: an approach of vascular development chronology in psoriasis. Journal of Dermatological Science, 57 (3), 162-169. doi:10.1016/j.jdermsci.2009.12.006

Lecut, C., Frederix, K., Johnson, D. M., Deroanne, C., Thiry, M., Faccinetto, C., Marée, R., Evans, R. J., Volders, P. G., Bours, V., & Oury, C. (2009). P2X1 Ion Channels Promote Neutrophil Chemotaxis through Rho Kinase Activation. Journal of Immunology. doi:10.4049/jimmunol.0804007

Borlon, C., Weemaels, G., Godard, P., Debacq-Chainiaux, F., Lemaire, P., Deroanne, C., & Toussaint, O. (2008). Expression profiling of senescent-associated genes in human dermis from young and old donors. Proof-of-concept study. Biogerontology, 9 (3), 197-208. doi:10.1007/s10522-008-9127-9

Chretien, A., Dierick, J.-F., Delaive, E., Larsen, M. R., Dieu, M., Raes, M., Deroanne, C., Roepstorff, P., & Toussaint, O. (2008). Role of TGF-beta1-independent changes in protein neosynthesis, p38alphaMAPK, and cdc42 in hydrogen peroxide-induced senescence-like morphogenesis. Free Radical Biology and Medicine, 44 (9), 1732-51. doi:10.1016/j.freeradbiomed.2008.01.026

Ho, T. T. G., Merajver, S. D., Lapière, C., Nusgens, B., & Deroanne, C. (2008). RhoA-GDP regulates RhoB protein stability. Potential involvement of RhoGDIalpha. Journal of Biological Chemistry, 283 (31), 21588-98. doi:10.1074/jbc.M710033200

Nikolova, E., Mitev, V., Minner, F., Deroanne, C., & Poumay, Y. (2008). The inhibition of the expression of the small Rho GTPase Rac1 induces differentiation with no effect on cell proliferation in growing human adult keratinocytes. Journal of Cellular Biochemistry, 103 (3), 857-64. doi:10.1002/jcb.21455

Mineur, P., Colige, A., Deroanne, C., Dubail, J., Kesteloot, F., Habraken, Y., Noël, A., Voo, S., Waltenberger, J., Lapière, C. M., Nusgens, B., & Lambert, C. (17 December 2007). Newly identified biologically active and proteolysis-resistant VEGF-A isoform VEGF111 is induced by genotoxic agents. Journal of Cell Biology, 179 (6), 1261-1273. doi:10.1083/jcb.200703052

Nikolova, E., Mitev, V., Zhelev, N., Deroanne, C., & Poumay, Y. (2007). The small Rho GTPase Rac1 controls normal human dermal fibroblasts proliferation with phosphorylation of the oncoprotein c-myc. Biochemical and Biophysical Research Communications, 359 (3), 834-9. doi:10.1016/j.bbrc.2007.05.214

Rosso, L., Pierson, P. M., Golfier, C., Peteri-Brunback, B., Deroanne, C., Van Obberghen-Schilling, E., & Mienville, J.-M. (2007). Pituicyte stellation is prevented by RhoA-or Cdc42-dependent actin polymerization. Cellular and Molecular Neurobiology, 27 (6), 791-804. doi:10.1007/s10571-007-9176-7

Servotte, S., Camby, I., Debeir, O., Deroanne, C., Lambert, C., Lapiere, C. M., Kiss, R., Nusgens, B., & Decaestecker, C. (December 2006). The in vitro influences of neurotensin on the motility characteristics of human U373 glioblastoma cells. Neuropathology and Applied Neurobiology, 32 (6), 575-584. doi:10.1111/j.1365-2990.2006.00760.x

Defawe, O. D., Kenagy, R. D., Choi, C., Wan, S. Y. C., Deroanne, C., Nusgens, B., SakalihasanN, N., Colige, A., & Clowes, A. W. (2005). MMP-9 regulates both positively and negatively collagen gel contraction - A nonproteolytic function of MMP-9. Cardiovascular Research, 66 (2), 402-409. doi:10.1016/j.cardiores.2004.11.025

Deroanne, C., Hamelryckx, D., Ho, T. T. G., Lambert, C., Catroux, P., Lapiere, C. M., & Nusgens, B. (2005). Cdc42 downregulates MMP-1 expression by inhibiting the ERK1/2 pathway. Journal of Cell Science, 118 (Pt 6), 1173-83. doi:10.1242/jcs.01707

Lambert, C., Deroanne, C., Servotte, S., Mineur, P., Lapiere, C. M., & Nusgens, B. (2005). Cell survival and preservation of siRNA-mediated protein knock-down upon serum-free cryopreservation (-80 degrees C). Gravitational and Space Biology Bulletin, 18 (2), 103-4.

Seite, S., Colige, A., Deroanne, C., Lambert, C., Piquemal-Vivenot, P., Montastier, C., Fourtanier, A., Lapière, C.-L., & Nusgens, B. (March 2004). Changes in matrix gene and protein expressions after single or repeated exposure to one minimal erythemal dose of solar-simulated radiation in human skin in vivo. Photochemistry and Photobiology, 79 (3), 265-271. doi:10.1562/YG-03-09.1

Defawe, O., Colige, A., Deroanne, C., Nusgens, B., Lapière, C., Limet, R., & Sakalihasan, N. (2004). MECHANICAL STRAIN MODULATES MONOCYTE CHEMOTACTIC PROTEIN-1 AND IL-1BETA EXPRESSION BY CULTURED HUMAN AORTIC SMOOTH MUSCLE CELLS. Cardiovascular Pathology, 13 (3 suppl), 189.

Deroanne, C., Vouret-Craviari, V., Wang, B., & Pouyssegur, J. (2003). EphrinA1 inactivates integrin-mediated vascular smooth muscle cell spreading via the Rac/PAK pathway. Journal of Cell Science, 116 (Pt 7), 1367-76. doi:10.1242/jcs.00308

Rosso, L., Peteri-Brunback, B., Vouret-Craviari, V., Deroanne, C., Troadec, J.-D., Thirion, S., Van Obberghen-Schilling, E., & Mienville, J.-M. (2002). RhoA inhibition is a key step in pituicyte stellation induced by A(1)-type adenosine receptor activation. Glia, 38 (4), 351-62. doi:10.1002/glia.10072

Rosso, L., Peteri-Brunback, B., Vouret-Craviari, V., Deroanne, C., Van Obberghen-Schilling, E., & Mienville, J.-M. (2002). Vasopressin and oxytocin reverse adenosine-induced pituicyte stellation via calcium-dependent activation of Cdc42. European Journal of Neuroscience, 16 (12), 2324-32. doi:10.1046/j.1460-9568.2002.02401.x

Hajitou, A., Sounni, N. E., Devy, L., Grignet, C., Lewalle, J.-M., Li, H., Deroanne, C., Lu, H., Colige, A., Nusgens, B., Frankenne, F., Maron, A., Yeh, P., Perricaudet, M., Chang, Y., Soria, C., Calberg-Bacq, C.-M., Foidart, J.-M., & Noël, A. (15 April 2001). Down-Regulation of Vascular Endothelial Growth Factor by Tissue Inhibitor of Metalloproteinase-2: Effect on in Vivo Mammary Tumor Growth and Angiogenesis. Cancer Research, 61 (8), 3450-7.

Deroanne, C., Lapiere, C. M., & Nusgens, B. (2001). In vitro tubulogenesis of endothelial cells by relaxation of the coupling extracellular matrix-cytoskeleton. Cardiovascular Research, 49 (3), 647-58. doi:10.1016/S0008-6363(00)00233-9

Hajitou, A., Deroanne, C., Noël, A., Collette, J., Nusgens, B., Foidart, J.-M., & Calberg-Bacq, C. M. (March 2000). Progression in MCF-7 Breast Cancer Cell Tumorigenicity: Compared Effect of FGF-3 and FGF-4. Breast Cancer Research and Treatment, 60 (1), 15-28. doi:10.1023/A:1006302602261

Deroanne, C., Hajitou, A., Calberg-Bacq, C.-M., Nusgens, B., & Lapière, C. M. (15 December 1997). Angiogenesis by Fibroblast Growth Factor 4 Is Mediated through an Autocrine Up-regulation of Vascular Endothelial Growth Factor Expression. Cancer Research, 57, 5590-5597.

Feller, G., Lonhienne, T., Deroanne, C., Libioulle, C., Van Beeumen, J., & Gerday, C. (15 March 1992). Purification, Characterization, and Nucleotide Sequence of the Thermolabile Alpha-Amylase from the Antarctic Psychrotroph Alteromonas Haloplanctis A23. Journal of Biological Chemistry, 267 (8), 5217-21.