Ancel, J., Dormoy, V., Raby, B. N., Dalstein, V., Durlach, A., Dewolf, M., Gilles, C., Polette, M., & Deslée, G. (2023). Soluble biomarkers to predict clinical outcomes in non-small cell lung cancer treated by immune checkpoints inhibitors. Frontiers in Immunology, 14, 1171649. doi:10.3389/fimmu.2023.1171649 |
Villard, A., Genna, A., Lambert, J., Volpert, M., Noël, A., Hollier, B., Polette, M., Vanwynsberghe, A., & Gilles, C. (July 2022). Regulation of Tissue Factor by CD44 supports coagulant activity in breast tumor cells. Cancers, 14 (3288). doi:10.3390/cancers14133288 |
Neyrinck-Leglantier, D., Lesage, J., Blacher, S., Bonnomet, A., Hunziker, W., Noël, A., Dormoy, V., Nawrocki-Raby, B., Gilles, C.* , & Polette, M.*. (December 2021). ZO-1 Intracellular Localization Organizes Immune Response in Non-Small Cell Lung Cancer. Frontiers in Cell and Developmental Biology, 9, 749364. doi:10.3389/fcell.2021.749364 * These authors have contributed equally to this work. |
Ancel, J., Perotin, J.-M., Dewolf, M., Launois, C., Mulette, P., Nawrocki-Raby, B., Dalstein, V., Gilles, C., Deslée, G., Polette, M., & Dormoy, V. (July 2021). Hypoxia in Lung Cancer Management: A Translational Approach. Cancers, 13 (14), 3421. doi:10.3390/cancers13143421 |
Ancel, J., Dewolf, M., Deslée, G., Nawrocki-Raby, B., Dalstein, V., Gilles, C.* , & Polette, M.*. (2020). Clinical Impact of the Epithelial-Mesenchymal Transition in Lung Cancer as a Biomarker Assisting in Therapeutic Decisions. Cells, Tissues, Organs. doi:10.1159/000510103 * These authors have contributed equally to this work. |
Burr, R., Gilles, C., Thompson, E., & Maheswaran, S. (2020). Epithelial-Mesenchymal Plasticity in Circulating Tumor Cells, the Precursors of Metastasis. Advances in Experimental Medicine and Biology, 1220, 11-34. doi:10.1007/978-3-030-35805-1_2 |
Francart, M.-E.* , Vanwynsberghe, A.* , Lambert, J., Bourcy, M., Genna, A., Ancel, J., Perez-Boza, J., Noël, A., Birembaut, P., Struman, I., Polette, M., & Gilles, C. (2020). Vimentin prevents a miR-dependent negative regulation of tissue factor mRNA during epithelial-mesenchymal transitions and facilitates early metastasis. Oncogene, 18, 3680-3692. doi:10.1038/s41388-020-1244-1 * These authors have contributed equally to this work. |
Genna, A.* , Vanwynsberghe, A.* , Villard, A.* , POTTIER, C., Ancel, J., Polette, M., & Gilles, C. (2020). EMT-Associated Heterogeneity in Circulating Tumor Cells : Sticky Friends on the Road to Metastasis. Cancers, 12 (6), 1632. doi:10.3390/cancers12061632 * These authors have contributed equally to this work. |
Ancel, J., Birembaut, P., de Wolf, M., Durlach, A., Nawrocki-Raby, B., Dalstein, V., Delepine, G., Blacher, S., Deslée, G., Gilles, C., & Polette, M. (19 September 2019). Programmed death–ligand 1 and vimentin: A tandem marker as prognostic factor in NSCLC. Cancers, 11 (10), 1411. doi:10.3390/cancers11101411 |
Sepult, C., Bellefroid, M., Rocks, N., Donati, K., Gérard, C., Gilles, C., Ludwig, A., Duysinx, B., Noël, A., & Cataldo, D. (2019). ADAM10 mediates malignant pleural mesothelioma invasiveness. Oncogene. doi:10.1038/s41388-018-0669-2 |
Francart, M.-E., Lambert, J., Vanwynsberghe, A., Thompson, E., Bourcy, M., Polette, M., & Gilles, C. (2018). Epithelial-Mesenchymal Plasticity and Circulating Tumor Cells: Travel Companions to Metastases. Developmental Dynamics, 247 (3), 432-450. doi:10.1002/dvdy.24506 |
Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., ... Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique. |
Vandereyken, M., Jacques, S., Van Overmeire, E., Amand, M., Rocks, N., Delierneux, C., Singh, P., Singh, M., GHUYSEN, C., Wathieu, C., Zurashvili, T., Sounni, N. E., Moutschen, M., Gilles, C., Oury, C., Cataldo, D., Van Ginderachter, J. A., & Rahmouni, S. (2017). Dusp3 deletion in mice promotes experimental lung tumour metastasis in a macrophage dependent manner. PLoS ONE. doi:10.1371/journal.pone.0185786 |
Francart, M.-E., Bourcy, M., Lambert, J., Vanwynsberghe, A., & Gilles, C. (25 June 2017). Regulation of Tissue Factor by Epithelial-to-Mesenchymal Transitions: Impacts for the metastatic progression [Poster presentation]. EACR-AACR-SIC Special Conference 2017, Florence, Italy. |
Suarez-Carmona, M., Lesage, J., Cataldo, D., & Gilles, C. (09 June 2017). EMT and inflammation: inseparable actors of cancer progression. Molecular Oncology, 11 (7), 805-823. doi:10.1002/1878-0261.12095 |
Francart, M.-E., Bourcy, M., Lambert, J., Noël, A., & Gilles, C. (01 February 2017). Regulation of Tissue Factor by Epithelial-to-Mesenchymal Transitions: Impacts for the metastatic progression [Poster presentation]. GIGA Day 2017, Liège, Belgium. |
Hugo, H., Gunasinghe, N., Hollier, B., Tanaka, T., Blick, T., Toh, A., Hill, P., Gilles, C., Waltham, M., & Thompson, E. (2017). Epithelial requirement for in vitro proliferation and xenograft growth and metastasis of MDA-MB-468 human breast cancer cells: oncogenic rather than tumor-suppressive role of E-cadherin. Breast Cancer Research, 19 (1), 86. doi:10.1186/s13058-017-0880-z |
Francart, M.-E., Bourcy, M., Lambert, J., Noël, A., & Gilles, C. (08 December 2016). Regulation of Tissue Factor by Epithelial-to-Mesenchymal Transitions: Impacts for the metastatic progression [Poster presentation]. TELEVIE's Researchers Seminar, Bruxelles, Belgium. |
Francart, M.-E., Bourcy, M., Lambert, J., Noël, A., & Gilles, C. (09 September 2016). Regulation of Tissue Factor by Epithelial-to-Mesenchymal Transitions: Impacts for the metastatic progression [Poster presentation]. Annual Mini Symposium 2016, Bruxelles, Belgium. |
Francart, M.-E., Bourcy, M., Suarez-Carmona, M., Lambert, J., Oury, C., Noël, A., & Gilles, C. (May 2016). Regulation of Tissue Factor by Epithelial-to-Mesenchymal Transitions: Impacts for the metastatic progression [Poster presentation]. Biomedica Life Sciences Summit 2016, Aachen, Germany. |
Bourcy, M., Suarez-Carmona, M., Lambert, J., Francart, M.-E., SCHROEDER, H., Delierneux, C., Skrypek, N., Thompson, E. W., JERUSALEM, G., Berx, G., Thiry, M., Blacher, S., Hollier, B. G., Noël, A., Oury, C., Polette, M., & Gilles, C. (2016). Tissue factor induced by epithelial-mesenchymal transition triggers a pro-coagulant state that drives metastasis of circulating tumor cells. Cancer Research, 76 (14), 4270-4282. |
Vandereyken, M., Amand, M., Van Overmeire, E., Zurashvili, T., MOUTSCHEN, M., Gilles, C., Van Ginderachter, J., & Rahmouni, S. (June 2015). Genetic depletion of the dual specificity protein phosphatase DUSP3 promotes LLC Lung tumour metastasis [Paper presentation]. Europhosphatase 2015: Phosphorylation switches and cellular homeostasis, Turku, Finland. |
Vandereyken, M., Amand, M., Van Overmeire, E., Zurashvili, T., MOUTSCHEN, M., Noël, A., Gilles, C., Van Ginderachter, J., & Rahmouni, S. (June 2015). Genetic depletion of the dual specificity protein phosphatase DUSP3 promotes LLC Lung tumour metastasis [Poster presentation]. Europhosphatase 2015: Phosphorylation switches and cellular homeostasis, Turku, Finland. |
Carnet, O.* , Lecomte, J.* , Masset, A., Primac, I., Durré, T., Maertens, L., Detry, B., Blacher, S., Gilles, C., Péqueux, C., Paupert, J., Foidart, J.-M., Jerusalem, G., Cataldo, D., & Noël, A. (2015). Mesenchymal stem cells shed amphiregulin at the surface of lung carcinoma cells in a juxtacrine manner. Neoplasia, 17 (7), 552-63. doi:10.1016/j.neo.2015.07.002 * These authors have contributed equally to this work. |
Suarez-Carmona, M., Bourcy, M., LESAGE, J., Leroi, N., Syne, L., Blacher, S., Hubert, P., Erpicum, C., Foidart, J.-M., Delvenne, P., Birembaut, P., Noël, A., Polette, M., & Gilles, C. (2015). Soluble factors regulated by epithelial-mesenchymal transition mediate tumour angiogenesis and myeloid cell recruitment. Journal of Pathology, 236 (4), 491-504. doi:10.1002/path.4546 |
Amand, M., Erpicum, C., BAJOU, K., Cerignoli, F., Blacher, S., Martin, M., Dequiedt, F., Drion, P., Singh, P., Zurashvili, T., Vandereyken, M., Musumeci, L., Mustelin, T., Moutschen, M., Gilles, C., Noël, A., & Rahmouni, S. (2014). DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase. Molecular Cancer. doi:10.1186/1476-4598-13-108 |
Koopmansch, B., Berx, G., Foidart, J.-M., Gilles, C., & Winkler, R. (22 February 2013). Interplay between KLF4 and ZEB2/SIP1 in the regulation of E-cadherin expression. Biochemical and Biophysical Research Communications, 431 (4), 652. doi:10.1016/j.bbrc.2013.01.070 |
Luczka, E., Syne, L., Nawrocki-Raby, B., Kileztky, C., Hunziker, W., Birembaut, P., Gilles, C., & Polette, M. (2013). Regulation of membrane-type 1 matrix metalloproteinase expression by zonula occludens-2 in human lung cancer cells. Clinical and Experimental Metastasis, 30 (7), 833-843. doi:10.1007/s10585-013-9583-8 |
Turtoi, A.* , Blomme, A.* , Bellahcene, A., Gilles, C., Hennequière, V., Peixoto, P., BIANCHI, E., Noël, A., De Pauw, E., LIFRANGE, E., Delvenne, P., & Castronovo, V. (2013). Myoferlin is a key regulator of EGFR activity in breast cancer. Cancer Research, 73, 5438-5448. doi:10.1158/0008-5472.CAN-13-1142 * These authors have contributed equally to this work. |
Brysse, A., Mestdagt, M., Polette, M., Luczka, E., Hunziker, W., Noël, A., Birembaut, P., Foidart, J.-M., & Gilles, C. (2012). Regulation of CXCL8/IL-8 expression by Zonula Occludens-1 in human breast cancer cells. Molecular Cancer Research, 10 (1), 121-32. doi:10.1158/1541-7786.MCR-11-0180 |
Delval, S., Taminiau, A., Lamy, J., Lallemand, C., Gilles, C., Noël, A., & Rezsohazy, R. (2011). The Pbx Interaction Motif of Hoxa1 Is Essential for Its Oncogenic Activity. PLoS ONE, 6 (9), 2547. doi:10.1371/journal.pone.0025247 |
Gilles, C., COLLIGNON, J., Noël, A., Jerusalem, G., & Foidart, J.-M. (2011). Cellules Tumorales Circulantes : détection, caractérisation et intérêts cliniques. Revue Médicale de Liège, 66 (5-6), 279-84. |
Noël, A., Gilles, C., & Foidart, J.-M. (2011). Invasion and metastatic dissemination in breast cancer: mechanisms. Revue Médicale de Liège, 66 (5-6), 274-278. |
Guéders, M., Hirst, S., Quesada Calvo, F., Paulissen, G., Hacha, J., Gilles, C., Gosset, P., Louis, R., Foidart, J.-M., Lopez-Otin, C., Noël, A., & Cataldo, D. (2010). MMP-19 Deficiency Promotes Tenascin-C Accumulation and Allergen-induced Airway Inflammation. American Journal of Respiratory Cell and Molecular Biology, 43 (3), 286-95. doi:10.1165/rcmb.2008-0426OC |
Herfs, M., Hubert, P., Kholod, N., Caberg, J.-H., Gilles, C., Berx, G., Savagner, P., Boniver, J., & Delvenne, P. (May 2008). Transforming growth factor-beta1-mediated Slug and Snail transcription factor up-regulation reduces the density of Langerhans cells in epithelial metaplasia by affecting E-cadherin expression. American Journal of Pathology, 172 (5), 1391-402. doi:10.2353/ajpath.2008.071004 |
Rocks, N.* , Estrella, C.* , Paulissen, G., Quesada Calvo, F., Gilles, C., Guéders, M., Crahay, C., Foidart, J.-M., Gosset, P., Noël, A., & Cataldo, D. (2008). the metalloproteinase ADAM-12 regulates bronchial epithelial cell proliferation and apoptosis. Cell Proliferation, 41 (6), 988-1001. doi:10.1111/j.1365-2184.2008.00557.x * These authors have contributed equally to this work. |
Rocks, N., Paulissen, G., Quesada Calvo, F., Alvarez Gonzalez, M.-L., Guéders, M., Hacha, J., Gilles, C., Foidart, J.-M., Noël, A.* , & Cataldo, D.*. (2008). ADAMTS-1 metalloproteinase induces a stromal reaction and propotes tumor development in mice. Cancer Research, 68 (22), 9541-50. doi:10.1158/0008-5472.CAN-08-0548 * These authors have contributed equally to this work. |
Polette, M., Mestdagt, M., Bindels, S., Nawrocki-Raby, B., Hunziker, W., Foidart, J.-M., Birembaut, P., & Gilles, C. (2007). beta-Catenin and ZO-1: Shuttle molecules involved in tumor invasion-associated epithelial-mesenchymal transition processes. Cells, Tissues, Organs, 185 (1-3), 61-65. doi:10.1159/000101304 |
Bindels, S., Mestdagt, M., Van de Walle, C., Jacobs, N., Volders, L., Noël, A., van Roy, F., Berx, G., Foidart, J.-M., & Gilles, C. (17 August 2006). Regulation of vimentin by SIP1 in human epithelial breast tumor cells. Oncogene, 25 (36), 4975-4985. doi:10.1038/sj.onc.1209511 |
Chabottaux, V., Sounni, N. E., Pennington, C. J., English, W. R., van den Brule, F., Blacher, S., Gilles, C., Munaut, C., Maquoi, E., Lopez-Otin, C., Murphy, G., Edwards, D. R., Foidart, J.-M., & Noël, A. (15 May 2006). Membrane-type 4 matrix metalloproteinase promotes breast cancer growth and metastases. Cancer Research, 66 (10), 5165-5172. doi:10.1158/0008-5472.CAN-05-3012 |
Mestdagt, M., Polette, M., Buttice, G., Noël, A., Ueda, A., Foidart, J.-M., & Gilles, C. (01 January 2006). Transactivation of MCP-1/CCL2 by beta-catenin/TCF-4 in human breast cancer cells. International Journal of Cancer, 118 (1), 35-42. doi:10.1002/ijc.21291 |
Polette, M., Gilles, C., Nawrocki-Raby, B., Lohi, J., Hunziker, W., Foidart, J.-M., & Birembaut, P. (01 September 2005). Membrane-type 1 matrix metalloproteinase expression is regulated by zonula occludens-1 in human breast cancer cells. Cancer Research, 65 (17), 7691-7698. doi:10.1158/0008-5472.CAN-04-4230 |
Laurent-Matha, V., Maruani-Herrmann, Glondu, M., Prebois, C., Gilles, C., Noël, A., Alvarez Gonzalez, M.-L., Blacher, S., Freiss, G., Vignon, F., & Liaudet-Coopman, E. (2005). Catalytically-inactive human cathepsin D triggers fibroblast invasive growth. Journal of Cell Biology, 168 (3), 489-99. doi:10.1083/jcb.200403078 |
Sounni, N. E., Roghi, C., Chabottaux, V., Janssen, M., Munaut, C., Maquoi, E., Galvez, B. G., Gilles, C., Frankenne, F., Murphy, G., Foidart, J.-M., & Noël, A. (02 April 2004). Up-regulation of vascular endothelial growth factor-A by active membrane-type 1 matrix metalloproteinase through activation of Src-tyrosine kinases. Journal of Biological Chemistry, 279 (14), 13564-13574. doi:10.1074/jbc.M307688200 |
Gilles, C., Polette, M., Mestdagt, M., Nawrocki-Raby, B., Ruggeri, P., Birembaut, P., & Foidart, J.-M. (May 2003). Transactivation of vimentin by beta-catenin in human breast cancer cells. Cancer Research, 63 (10), 2658-2664. |
Gilles, C., Polette, M., Coraux, C., Tournier, J. M., Meneguzzi, G., Munaut, C., Volders, L., Rousselle, P., Birembaut, P., & Foidart, J.-M. (August 2001). Contribution of MT1-MMP and of Human Laminin-5 Gamma2 Chain Degradation to Mammary Epithelial Cell Migration. Journal of Cell Science, 114 (Pt 16), 2967-76. |
Martinella-Catusse, C., Polette, M., Noël, A., Gilles, C., Dehan, P., Munaut, C., Colige, A., Volders, L., Foidart, J.-M., & Birembaut, P. (2001). Down-Regulation of MT1-MMP expression by the alpha3 chain of type IV collagen inhibits bronchial tumor cell line invasion. Laboratory Investigation, 81, 167-175. doi:10.1038/labinvest.3780224 |
Gilles, C., Polette, M., Zahm, J. M., Tournier, J. M., Volders, L., Foidart, J.-M., & Birembaut, P. (December 1999). Vimentin Contributes to Human Mammary Epithelial Cell Migration. Journal of Cell Science, 112 ((Pt 24)), 4615-25. |
Legrand, C., Gilles, C., Zahm, J. M., Polette, M., Buisson, A. C., Kaplan, H., Birembaut, P., & Tournier, J. L. (1999). Airway epithelial cell migration dynamics. MMP-9 role in cell-extracellular matrix remodeling. Journal of Cell Biology, 146 (2), 517-29. doi:10.1083/jcb.146.2.517 |
Noël, A., Gilles, C., Bajou, K., Devy, L., Kebers, F., Lewalle, J. M., Maquoi, E., Munaut, C., Remacle, A., & Foidart, J.-M. (1997). Emerging Roles for Proteinases in Cancer. Invasion and Metastasis, 17 (5), 221-39. |
Polette, M., Gilles, C., Marchand, V., Lorenzato, M., Toole, B., Tournier, J. M., Zucker, S., & Birembaut, P. (1997). Tumor collagenase stimulatory factor (TCSF) expression and localization in human lung and breast cancers. Journal of Histochemistry and Cytochemistry, 45 (5), 703-9. doi:10.1177/002215549704500508 |
Gilles, C., Piette, J., Ploton, D., Doco-Fenzy, M., & Foidart, J.-M. (August 1996). Viral Integration Sites in Human Papilloma Virus-33-Immortalized Cervical Keratinocyte Cell Lines. Cancer Genetics and Cytogenetics, 90 (1), 63-9. doi:10.1016/0165-4608(96)00060-X |
Delvenne, P., al-Saleh, W., Gilles, C., Thiry, A., & Boniver, J. (1995). Inhibition of growth of normal and human papillomavirus-transformed keratinocytes in monolayer and organotypic cultures by interferon-gamma and tumor necrosis factor-alpha. American Journal of Pathology, 146 (3), 589-98. |