Publications and communications of Bernard Lakaye

Burniat, A., Noël, A., Colige, A., Vanderplasschen, A., de Kerchove d'Exaerde, A., Kupper Cardozo, A., Van Keymeulen, A., Moens, A., Bondue, A., Herpain, A., Marchant, A., Loumaye, A., Beck, B., Van den Heyden, B., Corvilain, B., Lakaye, B., Rogister, B., Malgrange, B., Michiels, C., ... Brunko, E. (2023). Cent scientifiques répliquent à SEA (Suppression des Expériences sur l’Animal vivant) et dénoncent sa désinformation. La Libre Belgique.

Seutin, V., WANG, F.-C., Lakaye, B., & Hansen, I. (17 December 2022). Les syndromes myasthéniques et myotoniques congénitaux: rencontre des sciences fondamentales et des sciences cliniques [Paper presentation]. Datablitz du service de neurologie du CHU de Liège, Liège, Belgium.

Jehasse, K., Massotte, L., Hartmann, S., Vitello, R., Ringlet, S., Vitello, M., Chua, H. C., Pless, S., Engel, D., Liégeois, J.-F., Lakaye, B., Roeper, J., & Seutin, V. (01 October 2021). The gating pore blocker 1-(2,4-xylyl)guanidinium selectively inhibits pacemaking of midbrain dopaminergic neurons. Neuropharmacology, 197, 1-15. doi:10.1016/j.neuropharm.2021.108722

Jehasse, K., Jacquerie, K., de Froidmont, A., Lemoine, C., Grisar, T., Stouffs, K., Lakaye, B., & Seutin, V. (2021). Functional analysis of the F337C mutation in the CLCN1 gene associated with dominant myotonia congenita reveals an alteration of the macroscopic conductance and voltage dependence. Molecular Genetics and Genomic Medicine, 1588. doi:10.1002/mgg3.1588

Sambon, M., Gorlova, A., Demelenne, A., Alhama-Riba, J., Coumans, B., Lakaye, B., Wins, P., Fillet, M., Anthony, D. C., Strekalova, T., & Bettendorff, L. (2020). Dibenzoylthiamine has powerful antioxidant and anti-inflammatory properties in cultured cells and in mouse models of stress and neurodegeneration. Biomedicines, 8, 361. doi:10.3390/biomedicines8090361

Gilsoul, M., Grisar, T., Delgado-Escueta, A. V., de Nijs, L., & Lakaye, B. (27 September 2019). Subtle brain developmental abnormalities in the pathogenesis of juvenile myoclonic epilepsy. Frontiers in Cellular Neuroscience, 13, 433. doi:10.3389/fncel.2019.00433

Bakker, J., Balthazart, J., Baron, F., Beguin, Y., Bettendorff, L., Blanpain, C., Bureau, F., Caers, J., Cani, P., Cataldo, D., Cornil, C., Clercx, C., Cloots, R., Colige, A., Daube, G., De Backer, O., de Kerchove d'Exaerde, A., Desmecht, D., Desmet, C., ... Wittamer, V. (2018). La souris, le patient, et le faux expert. Décryptage d'une mystification. Le Vif. L'Express.

Nganou, G., Gomes Da Silva, C., Gladwyn-Ng, I., Engel, D., Coumans, B., Delgado-Escueta, A. V., Tanaka, M., Nguyen, L., Grisar, T., de Nijs, L., & Lakaye, B. (2018). Importin-8 Modulates Division of Apical Progenitors, Dendritogenesis and Tangential Migration During Development of Mouse Cortex. Frontiers in Molecular Neuroscience, 11, 234. doi:10.3389/fnmol.2018.00234

Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., ... Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique.

Bailey, J.* , Patterson, C.* , de Nijs, L., Duron, R., Ngyen, V., Tanaka, M., Medina, M., Jara-Prado, A., Martinez-Juarez, I., Ochoa, A., Molina, Y., Suzuki, T., Alonso, M., Wight, J., Lin, Y., Guilhoto, L., Yacubian, E., Machado-Salas, J., Daga, A., ... Delgado-Escueta, A. (2017). EFHC1 variants in juvenile myoclonic epilepsy: reanalysis according to NHGRI and ACMG guidelines for assigning disease causality. Genetics in Medicine, 19, 144-156. doi:10.1038/gim.2016.86
* These authors have contributed equally to this work.

Gigliobianco, T., GANGOLF, M., Lakaye, B., Pirson, B., von Ballmoos, C., Wins, P., & Bettendorff, L. (January 2013). An alternative role of FoF1-ATP synthase in Escherichia coli: synthesis of thiamine triphosphate. Scientific Reports, 3 (1071). doi:10.1038/srep01071

Kohn, G., Delvaux, D., Lakaye, B., Servais, A.-C., Scholer, G., Fillet, M., Elias, B., Derochette, J.-M., Crommen, J., Wins, P., & Bettendorff, L. (12 September 2012). High inorganic triphosphatase activities in bacteria and mammalian cells: Identification of the enzymes involved. PLoS ONE, 7 (9), 43879. doi:10.1371/journal.pone.0043879

de Nijs, L., Wolkoff, N., Coumans, B., Delgado-Escueta, A., Grisar, T., & Lakaye, B. (2012). Mutations of EFHC1, linked to juvenile myoclonic epilepsy, disrupt radial and tangential migrations during brain development. Human Molecular Genetics, 21 (23), 5106-17. doi:10.1093/hmg/dds356

Grisar, T., Lakaye, B., de Nijs, L., LoTurco, J., Daga, A., & Delgado-Escueta, A. (2012). Myoclonin1/EFHC1 in cell division, neuroblast migration, synapse/dendrite formation in juvenile myoclonic epilepsy. In J. Noebels, M. Avoli, M. Rogawski, R. Olsen, ... A. Delgado-Escueta (Eds.), Jasper's Basic Mechanisms of the Epilepsies, 4th edition (National Center for Biotechnology Information, pp. 1-19). Bethesda (MD), United States: NCBI.

Delvaux, D., Murty, M. R. V. S., Gabelica, V., Lakaye, B., Lunin, V. V., Skarina, T., Onopriyenko, O., Kohn, G., Wins, P., De Pauw, E., & Bettendorff, L. (2011). A specific inorganic triphosphatase from Nitrosomonas europaea: structure and catalytic mechanism. Journal of Biological Chemistry, 286, 34023-34035. doi:10.1074/jbc.M111.233585

Gangolf, M., Czerniecki, J., Radermecker, M., Detry, O., NISOLLE, M., JOUAN, C., Martin, D., Chantraine, F., Lakaye, B., Wins, P., Grisar, T., & Bettendorff, L. (October 2010). Thiamine Status in Humans and Content of Phosphorylated Thiamine Derivatives in Biopsies and Cultured Cells. PLoS ONE, 5 (10), 13616. doi:10.1371/journal.pone.0013616

Gigliobianco, T., Lakaye, B., Wins, P., Elmoualij, B., Zorzi, W., & Bettendorff, L. (May 2010). Adenosine thiamine triphosphate accumulates in Escherichia coli cells in response to specific conditions of metabolic stress. BMC Microbiology, 10, 148. doi:10.1186/1471-2180-10-148

Didone, V., Tirelli, E., Quertemont, E., & Lakaye, B. (2010). Ethanol-induced behaviors in mice genetically deficient in MCH1 receptors. Alcoholism, Clinical and Experimental Research, 34 (8), 93A-93.

Leon, C., de Nijs, L., Chanas, G., Delgado-Escueta, A. V., Grisar, T., & Lakaye, B. (2010). Distribution of EFHC1 or myoclonin 1 in mouse neural structures. Epilepsy Research, 88, 196-207. doi:10.1016/j.eplepsyres.2009.11.009

Wortge, S., Eshkind, L., Cabezas-Wallscheid, N., Lakaye, B., Kim, J., Heck, R., Abassi, Y., Diken, M., Sprengel, R., & Bockamp, E. (2010). Tetracycline-controlled transgene activation using the ROSA26-iM2-GFP knock-in mouse strain permits GFP monitoring of DOX-regulated transgene-expression. BMC Developmental Biology, 10, 95. doi:10.1186/1471-213X-10-95

Gigliobianco, T., Lakaye, B., Makarchikov, A. F., Wins, P., & Bettendorff, L. (2008). Adenylate Kinase-Independent Thiamine Triphosphate Accumulation under Severe Energy Stress in Escherichia Coli. BMC Microbiology, 8, 16. doi:10.1186/1471-2180-8-16

Verlaet, M., Adamantidis, A., Coumans, B., Chanas, G., Zorzi, W., Heinen, E., Grisar, T., & Lakaye, B. (11 September 2002). Human immune cells express ppMCH mRNA and functional MCHR1 receptor. FEBS Letters, 527 (1-3), 205-210. doi:10.1016/S0014-5793(02)03232-5

Makarchikov, A. F., Luchko, A. A., Bettendorff, L., Lakaye, B., & Wins, P. (2002). Study of the role of ionogenic amino-acid residues in catalytic activity of thiamine triphosphatase from bovine kidney by means of chemical modification. News of Biomedical Sciences, 3, 66-70.

Thellin, O., Zorzi, W., Lakaye, B., De Borman, B., Coumans, B., Hennen, G., Grisar, T., Igout, A., & Heinen, E. (1999). Housekeeping Genes as Internal Standards: Use and Limits. Journal of Biotechnology, 75 (2-3), 291-5. doi:10.1016/S0168-1656(99)00163-7

Adam, M., Fraipont, C., Rhazi, N., Nguyen-Disteche, M., Lakaye, B., Frère, J.-M., Devreese, B., Van Beeumen, J., van Heijenoort, Y., van Heijenoort, J., & Ghuysen, J.-M. (October 1997). The Bimodular G57-V577 Polypeptide Chain of the Class B Penicillin-Binding Protein 3 of Escherichia Coli Catalyzes Peptide Bond Formation from Thiolesters and Does Not Catalyze Glycan Chain Polymerization from the Lipid II Intermediate. Journal of Bacteriology, 179 (19), 6005-6009. doi:10.1128/jb.179.19.6005-6009.1997

Granier, B., Jamin, M., Adam, M., Galleni, M., Lakaye, B., Zorzi, W., Grandchamps, J., Wilkin, J.-M., Fraipont, C., Joris, B., Duez, C., Nguyen-Distèche, M., Coyette, J., Leyh-Bouille, M., Dusart, J., Christians, L., Frère, J.-M., & Ghuysen, J.-M. (1994). Serine-Type D-Ala-D-Ala Peptidases and Penicillin-Binding Proteins. Methods in Enzymology, 244, 249-266. doi:10.1016/0076-6879(94)44021-2

Duez, C., Lakaye, B., Houba, S., Dusart, J., & Ghuysen, J.-M. (01 September 1990). Cloning, Nucleotide Sequence and Amplified Expression of the Gene Encoding the Extracellular Metallo (Zn) Dd-Peptidase of Streptomyces Albus G. FEMS Microbiology Letters, 71 (1-2), 215-219. doi:10.1016/0378-1097(90)90059-Y