Publications and communications of Catherine Sadzot

Articles in scientific journals with peer reviewing

Van Breedam, E., Buyle-Huybrecht, T., Govaerts, J., Meysman, P., Bours, A., Boeren, M., Di Stefano, J., Caers, T., De Reu, H., Dirkx, L., Schippers, J., Bartholomeus, E., Lebrun, M., Sadzot, C., Rybakowska, P., Alarcón-Riquelme, M. E., Marañón, C., Laukens, K., Delputte, P., ... Ponsaerts, P. (2023). Lack of strong innate immune reactivity renders macrophages alone unable to control productive Varicella-Zoster Virus infection in an isogenic human iPSC-derived neuronal co-culture model. Frontiers in Immunology, 14, 1177245. doi:10.3389/fimmu.2023.1177245

Boeren, M., Van Breedam, E., Buyle-Huybrecht, T., Lebrun, M., Meysman, P., Sadzot, C., Van Tendeloo, V. F., Mortier, G., Laukens, K., Ogunjimi, B., Ponsaerts, P., & Delputte, P. (14 November 2022). Activation of Interferon-Stimulated Genes following Varicella-Zoster Virus Infection in a Human iPSC-Derived Neuronal In Vitro Model Depends on Exogenous Interferon-α. Viruses, 14 (11), 2517. doi:10.3390/v14112517

Sanchez Gil, J., Dubois, M., Neirinckx, V., LOMBARD, A., Coppieters't Wallant, N., D'arrigo, P., Isci, D., Aldenhoff, T., Brouwers, B., Lassence, C., ROGISTER, B., Lebrun, M., & Sadzot, C. (2022). Nanobody-based retargeting of an oncolytic herpesvirus for eliminating CXCR4+ GBM cells: a proof-of-principle. Molecular Therapy: Oncolytics. doi:10.1016/j.omto.2022.06.002

Lebrun, M., Thelen, N., Thiry, M., Riva, L., Ote, I., Condé, C., Vandevenne, P., Di Valentin, E., BONTEMS, S., & Sadzot-Delvaux, C. (2014). Varicella-zoster virus induces the formation of dynamic nuclear capsid aggregates. Virology, 454-455, 311-27. doi:10.1016/j.virol.2014.02.023

Riva, L., Thiry, M., Lebrun, M., L'Homme, L., Piette, J., & Sadzot-Delvaux, C. (2014). Deletion of the ORF9p acidic cluster impairs the nuclear egress of Varicella-zoster virus capsids. Journal of Virology. doi:10.1128/JVI.03215-14

Bonanni, P., Gershon, A., Gershon, M., Kulcsár, A., Papaevangelou, V., Rentier, B., Sadzot-Delvaux, C., Usonis, V., Vesikari, T., Weil-Olivier, C., de Winter, P., & Wutzler, P. (2013). Primary Versus Secondary Failure After Varicella Vaccination: Implications for Interval Between 2 Doses. Pediatric Infectious Disease Journal, 32 (7), 305-313. doi:10.1097/INF.0b013e31828b7def

Vandevenne, P., Lebrun, M., El Mjiyad, N., Ote, I., Di Valentin, E., Habraken, Y., Dortu, E., Piette, J., & Sadzot-Delvaux, C. (February 2011). The varicella-zoster virus ORF47 kinase interferes with host innate immune response by inhibiting the activation of IRF3. PLoS ONE, 9 (2). doi:10.1371/journal.pone.0016870

Ote, I., Piette, J., & Sadzot-Delvaux, C. (2010). The Varicella-Zoster virus IE4 protein: a conserved member of the herpesviral mRNA export factors family and a potential alternative target in antiherpetic therapies. Biochemical Pharmacology, 80, 1973-1980. doi:10.1016/j.bcp.2010.07.011

Vandevenne, P., Sadzot-Delvaux, C., & Piette, J. (2010). Innate immune response and viral interference strategies developed by Human Herpeviruses. Biochemical Pharmacology, 80, 1955-1972. doi:10.1016/j.bcp.2010.07.001

Ote, I., Vandevenne, P., Bontems, S., Medina-Palazon, C., Manet, E., Piette, J., Lebrun, M., & Sadzot-Delvaux, C. (18 November 2009). Varicella-Zoster Virus IE4 Protein Interacts with SR Proteins and Exports mRNAs through the TAP/NXF1 Pathway. PLoS ONE, 4 (11), 7882. doi:10.1371/journal.pone.0007882

Bonanni, P., Breuer, J., Gershon, A. A., Gershon, M., Hryniewicz, W., Papaevangelou, V., Rentier, B., Rumke, H., Sadzot-Delvaux, C., Senterre, J., Weil-Olivier, C., & Wutzler, P. (28 May 2009). Varicella vaccination in Europe – taking the practical approach. BMC Medicine, 7 (26), 1-38. doi:10.1186/1741-7015-7-26

Sadzot-Delvaux, C., Rentier, B., Wutzler, P., Asano, Y., Suga, S., Yoshikawa, T., & Plotkin, S. A. (2008). Varicella vaccination in Japan, South Korea, and Europe. Journal of Infectious Diseases, 197 Suppl 2, 185-90. doi:10.1086/522163

Habran, L., El Mjiyad, N., Di Valentin, E., Sadzot-Delvaux, C., Bontems, S., & Piette, J. (October 2007). The varicella-zoster virus immediate-early 63 protein affects chromatin-controlled gene transcription in a cell-type dependent manner. BMC Molecular Biology, 8, 99. doi:10.1186/1471-2199-8-99

El Mjiyad, N., Bontems, S., Gloire, G., Horion, J., Vandevenne, P., Dejardin, E., Piette, J., & Sadzot-Delvaux, C. (2007). Varicella-zoster virus modulates NF-kappaB recruitment on selected cellular promoters. Journal of Virology, 81 (23), 13092-104. doi:10.1128/JVI.01378-07

Sadzot-Delvaux, C., Di Valentin, E., & Bontems, S. (2006). Le virus de la varicelle et du zona : un alphaherpesvirus pas vraiment comme les autres. Virologie, 10 (3), 219-232.

Cohen, J. I., Krogmann, T., Bontems, S., Sadzot-Delvaux, C., & Pesnicak, L. (2005). Regions of the varicella-zoster virus open reading frame 63 latency-associated protein important for replication in vitro are also critical for efficient establishment of latency. Journal of Virology, 79 (8), 5069-77. doi:10.1128/JVI.79.8.5069-5077.2005

Habran, L., Bontems, S., Di Valentin, E., Sadzot-Delvaux, C., & Piette, J. (2005). Varicella-zoster virus IE63 protein phosphorylation by roscovitine-sensitive cyclin-dependent kinases modulates its cellular localization and activity. Journal of Biological Chemistry, 280 (32), 29135-43. doi:10.1074/jbc.M503312200

Nikkels, A., Simonart, T., Kentos, A., Liesnard, C., Sadzot-Delvaux, C., Feremans, W., & Pierard, G. (2003). Atypical recurrent varicella in 4 patients with hemopathies. Journal of the American Academy of Dermatology, 48 (3), 442-7. doi:10.1067/mjd.2003.94

Bontems, S., Di Valentin, E., Baudoux, L., Rentier, B., Sadzot-Delvaux, C., & Piette, J. (07 June 2002). Phosphorylation of varicella-zoster virus IE63 protein by casein kinases influences its cellular localization and gene regulation activity. Journal of Biological Chemistry, 277 (23), 21050-21060. doi:10.1074/jbc.M111872200

Kennedy, P. G., Grinfeld, E., Bontems, S., & Sadzot-Delvaux, C. (2001). Varicella-Zoster virus gene expression in latently infected rat dorsal root ganglia. Virology, 289 (2), 218-23. doi:10.1006/viro.2001.1173

Rentier, B., & Sadzot-Delvaux, C. (2000). Le virus de la varicelle et du zona dans le système nerveux : retraite silencieuse ou guérilla permanente ? Virologie, 4 (3), 207-216.

Sadzot-Delvaux, C., Arvin, A. M., & Rentier, B. (November 1998). Varicella-zoster virus IE63, a virion component expressed during latency and acute infection, elicits humoral and cellular immunity. Journal of Infectious Diseases, 178 (Suppl. 1), 43-S47. doi:10.1086/514259

Piette, J., Defechereux-Thibaut de Maisières, P., Baudoux-Tebache, L., Sadzot-Delvaux, C., & Rentier, B. (1998). La régulation des cycles infectieux du virus de la varicelle et du zona. M S-Médecine Sciences, 14 (5), 556-565.

Sadzot-Delvaux, C., Kinchington, P. R., Debrus, S., Rentier, B., & Arvin, A. M. (1997). Recognition of the latency-associated immediate early protein IE63 of varicella-zoster virus by human memory T-lymphocytes. Journal of Immunology, 159 (6), 2802-2806.

Rentier, B., Piette, J., Baudoux, L., Debrus, S., Defechereux, P., Merville, M.-P., Sadzot-Delvaux, C., & Schoonbroodt, S. (November 1996). Lessons to be learned from varicella-zoster virus. Veterinary Microbiology, 53 (1-2), 55-66. doi:10.1016/S0378-1135(96)01234-5

Debrus, S., Sadzot-Delvaux, C., Nikkels, A., Piette, J., & Rentier, B. (1995). Varicella-zoster virus gene 63 encodes an immediate-early protein that is abundantly expressed during latency. Journal of Virology, 69 (5), 3240-3245. doi:10.1128/jvi.69.5.3240-3245.1995

Sadzot-Delvaux, C., Thonard, P., Schoonbroodt, S., Piette, J., & Rentier, B. (1995). Varicella-zoster virus induces apoptosis in cell culture. Journal of General Virology, 76 (Pt 11), 2875-2879. doi:10.1099/0022-1317-76-11-2875

Snoeck, R., Gerard, M., Sadzot-Delvaux, C., Andrei, G., Balzarini, J., Reymen, D., Piette, J., Rentier, B., Clumeck, N., & De Clercq, E. (1993). Meningoradiculoneuritis due to acyclovir-resistant varicella-zoster virus in a patient with aids. Journal of Infectious Diseases, 168 (5), 1330-1331. doi:10.1093/infdis/168.5.1330

Sadzot-Delvaux, C., Marc, P., Lebon, L., Merville, M.-P., Piette, J., & Rentier, B. (1992). Antibodies to varicella-zoster virus modulate antigen distribution but fail to induce viral persistence in vitro. Journal of Virology, 66 (12), 7499-504. doi:10.1128/jvi.66.12.7499-7504.1992

Merville-Louis, M. P., Sadzot-Delvaux, C., Delree, P., Piette, J., Moonen, G., & Rentier, B. (1989). Varicella-zoster virus infection of adult rat sensory neurons in vitro. Journal of Virology, 63 (7), 3155-60. doi:10.1128/jvi.63.7.3155-3160.1989

Scientific congresses and symposiums

Published communications

Nikkels, A., Debrus, S., Sadzot-Delvaux, C., Rentier, B., & Pierard, G. (1994). Immunohistochemical detection of immediate early and late phase proteins expressed during the varicella-zoster virus cycle. British Journal of Dermatology. Supplement, 131 (44), 64.

Nikkels, A., Sadzot-Delvaux, C., Cloes, J.-M., Rentier, B., & Pierard, G. (1992). Granulomatous reactions following herpes-zoster contain varicella-zoster glycoprotein GPI. Journal of Investigative Dermatology, 98 (4), 522.

Oral communications or posters

D'arrigo, P., Sanchez Gil, J., Dubois, M., Lebrun, M., ROGISTER, B., & Sadzot, C. (02 August 2021). An armed oncolytic herpesvirus to counteract gioblastoma stem-like cells functions [Poster presentation]. International Herpesvirus Workshop.

Lambert, J., Sadzot, C., Lebrun, M., & Thiry, M. (Other coll.). (19 December 2019). Varicella Zoster Virus ORF9p: hijacker of the autophagy pathway? [Paper presentation]. Belvir 2019, Brussels, Belgium.

Sanchez Gil, J., Collignon, A., Lebrun, M., Rogister, B., Chevigné, A., & Sadzot, C. (15 January 2019). Construction of an oncolytic herpes virus (oHSV) for inducing apoptosis in glioblastoma: proof of concept [Poster presentation]. Seminaire Télévie- edition 2019, Gembolux, Belgium.

Sanchez Gil, J., Lebrun, M., Allegro, A., Chevigné, A., ROGISTER, B., & Sadzot, C. (2019). Targeting of CXCR4+ Glioblastoma initiating cells with a retargeted oncolytic herpesvirus [Poster presentation]. 12th International Oncolytic Virus conference, Rochester, United States - Minnesota.

Lambert, J., Lebrun, M., Riva, L., Sanchez Gil, J., Sadzot-Delvaux, C., Andrei, G. (Other coll.), & Snoeck, R. (Other coll.). (29 July 2017). Study of the role of the complex formed by the Varicella Zoster virus ORF9p and the cellular Adaptin Protein-1 in the secondary egress [Poster presentation]. IHW 2017, Ghent, Belgium.

Lebrun, M., riva, L., lambert, J., Rambout, X., Thiry, M., blondeau, C., Twizere, J.-C., Dequiedt, F., & Sadzot-Delvaux, C. (20 May 2016). Role of Varicella Zoster virus ORF9p in the secondary egress : importance of its interaction with the cellular Adaptin Protein-1 [Poster presentation]. 2015 Colorado Alphaherpesvirus Latency Society Symposium, Vail, United States - Colorado.

Riva, L., Thiry, M., BONTEMS, S., Joris, A., Piette, J., Lebrun, M., & Sadzot-Delvaux, C. (28 January 2013). ORF9p phosphorylation by ORF47p is crucial for the formation and egress of Varicella-­‐ Zoster Virus viral particles [Poster presentation]. GIGA-Day, Liège, Belgium.

Book chapters and contributions to collective works

Sadzot-Delvaux, C., & Rentier, B. (2001). The role of varicella zoster virus immediate-early proteins in latency and their potential use as components of vaccines. In A. A. Gershon, C. H. Calisher, ... A. M. Arvin (Eds.), Immunity to and Prevention of Herpes Zoster (pp. 81-89). Springer. doi:10.1007/978-3-7091-6259-0_9

Other publications and communications

Articles in scientific journals without peer reviewing


Speeches and writings for a general audience

General audience and popularisation articles

Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., ... Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique.