Publications and communications of Marianne Fillet

Pierson, E., De Pol, F., Fillet, M., & Wouters, J. (10 October 2023). A morpheein equilibrium regulates catalysis in phosphoserine phosphatase SerB2 from Mycobacterium tuberculosis. Communications Biology, 6 (1), 1024. doi:10.1038/s42003-023-05402-z

Gallez, A., Nys, G., Wuidar, V., Dias Da Silva, I., Taziaux, M., Kinet, V., Tskitishvili, E., Noël, A., Foidart, J.-M., Piel, G., Fillet, M., & Pequeux, C. (03 June 2023). Comparison of Estetrol Exposure between Women and Mice to Model Preclinical Experiments and Anticipate Human Treatment. International Journal of Molecular Sciences, 24 (11), 9718. doi:10.3390/ijms24119718

Mauri, S., Bernardo, G., Martinez, A., Favaro, M., Trevisan, M., Cobraiville, G., Fillet, M., Caicci, F., Whitworth, A. J., & Ziviani, E. (13 April 2023). USP8 Down-Regulation Promotes Parkin-Independent Mitophagy in the Drosophila Brain and in Human Neurons. Cells, 12 (8), 1143. doi:10.3390/cells12081143

Kumari, P., Van Laethem, T., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (10 February 2023). Quantitative Structure Retention-Relationship Modeling: Towards an Innovative General-Purpose Strategy. Molecules, 28 (4), 1696. doi:10.3390/molecules28041696

Lejeune, M., Köse, M. C., Jassin, M., Gou, M.-J., Herbet, A., Duray, E., Cobraiville, G., FOGUENNE, J., Boquet, D., Gothot, A., Beguin, Y., Fillet, M., & Caers, J. (2023). Integrative Analysis of Proteomics and Transcriptomics Reveals Endothelin Receptor B as Novel Single Target and Identifies New Combinatorial Targets for Multiple Myeloma. HemaSphere, 22, 901. doi:10.1097/HS9.0000000000000901

Schmitz, L., Pirotte, M., Lebeau, A., Ernst, M., Fillet, M., DEVEY, A., SCHMITT, J., Cobraiville, G., BINSFELD, M., Gofflot, S., Beguin, Y.* , & Vertenoeil, G.*. (2023). Alterations of erythropoiesis in Covid-19 patients: prevalence of positive Coombs tests and iron metabolism. Therapeutic Advances in Hematology, 14, 20406207231199837. doi:10.1177/20406207231199837
* These authors have contributed equally to this work.

Van Laethem, T., Kumari, P., Boulanger, B., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (28 November 2022). User-Driven Strategy for In Silico Screening of Reversed-Phase Liquid Chromatography Conditions for Known Pharmaceutical-Related Small Molecules. Molecules, 27 (23), 8306. doi:10.3390/molecules27238306

Köse, M. C., Lejeune, M., Gou, M.-J., Duray, E., Cobraiville, G., Gothot, A., Beguin, Y., Fillet, M., & Caers, J. (15 November 2022). Integrative Analysis of Proteomics and Transcriptomics Reveals the Etrb As Novel Single Target and New Combinatorial Targets for Multiple Myeloma [Paper presentation]. ASH 2022 Symposium, New orleans, United States.

Farre Segura, J., Le Goff, C., LUKAS, P., Cobraiville, G., Fillet, M., Servais, A.-C., Delanaye, P., & Cavalier, E. (03 November 2022). Validation of an LC-MS/MS Method Using Solid-Phase Extraction for the Quantification of 1-84 Parathyroid Hormone: Toward a Candidate Reference Measurement Procedure. Clinical Chemistry, 68 (11), 1399-1409. doi:10.1093/clinchem/hvac135

Gou, M.-J., Köse, M. C., Crommen, J., Nix, C., Cobraiville, G., Caers, J., & Fillet, M. (01 November 2022). Contribution of Capillary Zone Electrophoresis Hyphenated with Drift Tube Ion Mobility Mass Spectrometry as a Complementary Tool to Microfluidic Reversed Phase Liquid Chromatography for Antigen Discovery. International Journal of Molecular Sciences, 23 (21), 13350. doi:10.3390/ijms232113350

Lu, L., Liu, X., Zuo, C., Zhou, J., Zhu, C., Zhang, Z., Fillet, M., Crommen, J., Jiang, Z., & Wang, Q. (08 September 2022). In vitro/in vivo degradation analysis of trastuzumab by combining specific capture on HER2 mimotope peptide modified material and LC-QTOF-MS. Analytica Chimica Acta, 1225, 340199. doi:10.1016/j.aca.2022.340199

Nix, C., Cobraiville, G., Gou, M.-J., & Fillet, M. (06 July 2022). Potential of Single Pulse and Multiplexed Drift-Tube Ion Mobility Spectrometry Coupled to Micropillar Array Column for Proteomics Studies. International Journal of Molecular Sciences, 23 (14), 7497. doi:10.3390/ijms23147497

Van Laethem, T., Kumari, P., Hubert, P., Fillet, M., Sacre, P.-Y., & Hubert, C. (June 2022). A pharmaceutical-related molecules dataset for reversed-phase chromatography retention time prediction built on combining pH and gradient time conditions. Data in Brief, 42, 108017. doi:10.1016/j.dib.2022.108017

Lebeau, A.* , Bruyère, D.* , RONCARATI, P., Peixoto, P., Hervouet, E., COBRAIVILLE, G., Taminiau, B., Masson, M., Gallego, C., Mazzucchelli, G., Smargiasso, N., Fleron, M., Baiwir, D., Hendrick, E., Pilard, C., Lerho, T., Reynders, C., Ancion, M., GREIMERS, R., ... Herfs, M. (28 February 2022). HPV infection alters vaginal microbiome through down-regulating host mucosal innate peptides used by Lactobacilli as amino acid sources. Nature Communications, 13 (1), 1076. doi:10.1038/s41467-022-28724-8
* These authors have contributed equally to this work.

Davoine, C., Pardo, A., Pochet, L., & Fillet, M. (09 November 2021). Fragment Hit Discovery and Binding Site Characterization by Indirect Affinity Capillary Electrophoresis: Application to Factor XIIa. Analytical Chemistry, 93, 14802–14809. doi:10.1021/acs.analchem.1c03611

CIREGIA, F., Nys, G., Cobraiville, G., Badot, V., Di Romana, S., Sidiras, P., Sokolova, T., Durez, P., Fillet, M., Malaise, M., & de Seny, D. (2021). A Cross-Sectional and Longitudinal Study to Define Alarmins and A-SAA Variants as Companion Markers in Early Rheumatoid Arthritis. Frontiers in Immunology. doi:10.3389/fimmu.2021.638814

Ilangala Booka, A., Lechanteur, A., Fillet, M., & Piel, G. (2021). Therapeutic peptides for chemotherapy: trends and challenges for advanced delivery systems. European Journal of Pharmaceutics and Biopharmaceutics. doi:10.1016/j.ejpb.2021.07.010

Davoine, C., Fillet, M., & Pochet, L. (26 May 2021). Uncovering biochemical assay’s false positives by counter-screening a fragment library with affinity capillary electrophoresis [Poster presentation]. CIRM-day 2021.

Davoine, C., Fillet, M., & Pochet, L. (01 May 2021). Capillary electrophoresis as a fragment screening tool to cross-validate hits from chromogenic assay: Application to FXIIa. Talanta, 226. doi:10.1016/j.talanta.2021.122163

Ciregia, F., DEROYER, C., COBRAIVILLE, G., PLENER, Z., MALAISE, O., GILLET, P., Fillet, M., MALAISE, M., & DE SENY, D. (2021). Modulation of αVβ6 integrin in osteoarthritis-related synovitis and the interaction with VTN (381-397 a.a.) competing for TGF-β1 activation. Experimental and Molecular Medicine. doi:10.1038/s12276-021-00558-2

de Bournonville, M.-P., de Bournonville, C., Vandries, L., Nys, G., Fillet, M., Ball, G., Balthazart, J., & Cornil, C. (2021). Rapid changes in brain estrogen concentration during male sexual behavior are site and stimulus specific. Scientific Reports, 11 (1), 20130. doi:10.1038/s41598-021-99497-1

Demelenne, A., Ben Yahia, A., Lempereur, D., Crommen, J., Servais, A.-C., Fradi, I., & Fillet, M. (2021). Comparison of Three Complementary Analytical Techniques for the Evaluation of the Biosimilar Comparability of a Monoclonal Antibody and an Fc-Fusion Protein. Frontiers in Chemistry, 9, 782099. doi:10.3389/fchem.2021.782099

Nix, C., Hemmati, M., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (2021). Blood Microsampling to Monitor Metabolic Profiles During Physical Exercise. Frontiers in Molecular Biosciences. doi:10.3389/fmolb.2021.681400

PIROTTE, M., Fillet, M., SEIDEL, L., JASPERS, A., Baron, F., & Beguin, Y. (2021). Erythroferrone and hepcidin as mediators between erythropoiesis and iron metabolism during allogeneic hematopoietic stem cell transplant. American Journal of Hematology, 96 (10), 1275-1286. doi:10.1002/ajh.26300

Davoine, C., Bouckaert, C., Fillet, M., & Pochet, L. (15 December 2020). Factor XII/XIIa inhibitors: Their discovery, development, and potential indications. European Journal of Medicinal Chemistry, 208. doi:10.1016/j.ejmech.2020.112753

Ledoux, A., Coelho Cristino Mamede, L. C., Palazzo, C., Furst, T., Jansen, O., De Tullio, P., Kagisha, V., Pendeville-Samain, H., Fillet, M., Piel, G., & Frederich, M. (18 May 2020). Heparin-Coated Liposomes Improve Antiplasmodial Activity and Reduce the Toxicity of Poupartone B. Planta Medica International Open, 7 (e), 73–80. doi:10.1055/a-1158-0569

Demelenne, A., Gou, M.-J., Nys, G., Parulski, C., Crommen, J., Servais, A.-C., & Fillet, M. (2020). Evaluation of Hydrophilic Interaction Liquid Chromatography, Capillary Zone Electrophoresis and Drift Tube Ion-Mobility Quadrupole Time Of Flight mass spectrometry for the characterization of phosphodiester and phosphorothioate oligonucleotides. Journal of Chromatography. A. doi:10.1016/j.chroma.2019.460716

Oury, C., MARECHAL, P., Donis, N., Hulin, A., Hego, A., TRIDETTI, J., Nguyen, M.-L., DULGHERU, R. E., Fillet, M., Nchimi Longang, A., & Lancellotti, P. (2020). Dexfenfluramine and Pergolide Cause Heart Valve Disease via Valve Metabolic Reprogramming and Ongoing Matrix Remodeling. International Journal of Molecular Sciences, 21 (11). doi:10.3390/ijms21114003

Sambon, M., Gorlova, A., Demelenne, A., Alhama-Riba, J., Coumans, B., Lakaye, B., Wins, P., Fillet, M., Anthony, D. C., Strekalova, T., & Bettendorff, L. (2020). Dibenzoylthiamine has powerful antioxidant and anti-inflammatory properties in cultured cells and in mouse models of stress and neurodegeneration. Biomedicines, 8, 361. doi:10.3390/biomedicines8090361

Gou, M.-J., Nys, G., COBRAIVILLE, G., Demelenne, A., Servais, A.-C., & Fillet, M. (11 December 2019). Proteomic analysis using capillary electrophoresis hyphenated with high resolution mass spectrometry: comparison of two coupling interfaces [Poster presentation]. 2nd Cirm Day, Liège, Belgium.

Ilangala Booka, A., COBRAIVILLE, G., EVRARD, A., Sonveaux, Lechanteur, A., Piel, G., & Fillet, M. (11 December 2019). LC-UV as tool for nanovectorized anticancer peptide quality control: evaluation of encapsulation efficiency [Poster presentation]. 2nd Edition of CIRM day, Liege, Belgium.

Nys, G., COBRAIVILLE, G., Servais, A.-C., Malaise, M., DE SENY, D., & Fillet, M. (2019). Targeted proteomics reveals serum amyloid A variants and alarmins S100A8-S100A9 as key plasma biomarkers of rheumatoid arthritis. Talanta. doi:10.1016/j.talanta.2019.06.044

Nyssen, L., Fillet, M., CAVALIER, E., & Servais, A.-C. (26 September 2019). Separation of Intact Parathyroid Hormone and Variants Using a Highly Sensitive Sheathless CE-ESI-MS/MS Method [Poster presentation]. MSACL 2019 EU.

Radermecker, R., Demelenne, A., Desaive, T., & Fillet, M. (2019). Analyse des concentrations de quatre type d'insulines différentes ( humaine 100 IU/ml, aspart 100 IU/ml, lispro 200 IU/ml et glargine 300 IU/ml) provenant de trois sources différentes (pharmacie hospitalière , officine de ville , et échantillons procurés au diabétologue par les représentants de l’industrie ). . Diabetes and Metabolism.

Demelenne, A., NAPP, A., Bouillenne, F., Crommen, J., Servais, A.-C., & Fillet, M. (2019). Insulin aggregation assessment by capillary gel electrophoresis without sodium dodecyl sulfate: Comparison with size-exclusion chromatography. Talanta, 199, 457-463. doi:10.1016/j.talanta.2019.02.074

Sambon, M., NAPP, A., Demelenne, A., Vignisse, J., Wins, P., Fillet, M., & Bettendorff, L. (2019). Thiamine and benfotiamine protect neuroblastoma cells against paraquat and ß- amyloid toxicity by a coenzyme-independent mechanism. Heliyon, 5, 01710. doi:10.1016/j.heliyon.2019.e01710

Yazdani, R., Shams-Bakhsh, M., Hassani-Mehraban, A., Arab, S. S., Thelen, N., Thiry, M., Crommen, J., Fillet, M., Jacobs, N., Brans, A., & Servais, A.-C. (2019). Production and characterization of virus-like particles of grapevine fanleaf virus presenting L2 epitope of human papillomavirus minor capsid protein. BMC Biotechnology, 19 (1), 81. doi:10.1186/s12896-019-0566-y

Emonts, P., Dispas, A., Ninane, C. (Other coll.), Hubert, P. (Other coll.), Servais, A.-C. (Other coll.), Ziemons, E. (Other coll.), & Fillet, M. (Other coll.). (19 December 2018). Development and optimization of a derivatization protocol for phenethylamine compounds using FITC-CE-LIF method [Poster presentation]. 1st CIRM Scientific Day, Liège, Belgium.

Gou, M.-J., Demelenne, A., Parulski, C., Servais, A.-C., & Fillet, M. (19 December 2018). Quality control of therapeutic oligonucleotides using HILIC-UV and CZE-UV [Poster presentation]. CIRM Day, Liège, Belgium.

Demelenne, A., Napp, A., Servais, A.-C., & Fillet, M. (10 September 2018). Insulin aggregation assessment by size-exclusion chromatography and capillary gel electrophoresis [Poster presentation]. the 11th International Symposium on Drug Analysis and the 29th International Symposium on Pharmaceutical and Biomedical Analysis.

Nys, G., COBRAIVILLE, G., Servais, A.-C., & Fillet, M. (31 July 2018). (Nano)-LC coupled to Ion Mobility Q-TOF for an improved sensitivity and proteome coverage [Poster presentation]. HPLC 2018, United States - District of Columbia.

STREEL, S., Vercheval, C., Servais, A.-C., Fillet, M., & Van Hees, T. (24 February 2018). Stability of 90 mg/ml cefuroxime sodium solution for administration by continuous infusion [Poster presentation]. Assemble Générale de l'Association Francophone des Pharmaciens Hospitaliers de Belgique, Mons, Belgium.

Diepeveen, L. E., Laarakkers, C. M. M., Martos, G., Pawlak, M. E., Uǧuz, F. F., Verberne, K. E. S. A., Van Swelm, R. P. L., Klaver, S., De Haan, A. F. J., Pitts, K. R., Bansal, S. S., Abbas, I. M., Fillet, M., Lefebvre, T., Geurts-Moespot, A. J., Girelli, D., Castagna, A., Herkert, M., Itkonen, O., ... Swinkels, D. W. (2018). Provisional standardization of hepcidin assays: Creating a traceability chain with a primary reference material, candidate reference method and a commutable secondary reference material. Clinical Chemistry and Laboratory Medicine. doi:10.1515/cclm-2018-0783

Gemmel, M., Harmeyer, D., Bögi, E., Fillet, M., Hill, L. A., Hammond, G. L., Charlier, T. D., & Pawluski, J. L. (2018). Perinatal fluoxetine increases hippocampal neurogenesis and reverses the lasting effects of pre-gestational stress on serum corticosterone, but not on maternal behavior, in the rat dam. Behavioural Brain Research, 339, 222-231. doi:10.1016/j.bbr.2017.11.038

BEKAERT, S., Fillet, M., Detry, B., Pichavant, M., Marée, R., Noël, A., Rocks, N., & Cataldo, D. (21 December 2017). Inflammation-Generated Extracellular Matrix Fragments Drive Lung Metastasis. Cancer Growth and Metastasis, 10, 1-11. doi:10.1177/1179064417745539

Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., ... Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique.

Fettweis, G., Di Valentin, E., L'homme, L., Lassence, C., Dequiedt, F., Fillet, M., Coupienne, I., & Piette, J. (2017). RIP3 antagonizes a TSC2-mediated pro-survival pathway in glioblastoma cell death. Biochimica et Biophysica Acta. doi:10.1016/j.bbamcr.2016.10.014

DE SENY, D., COBRAIVILLE, G., Leprince, P., Fillet, M., Collin, C., Mathieu, M., HAUZEUR, J.-P., Gangji, V., & Malaise, M. (2016). Biomarkers of inflammation and innate immunity in atrophic nonunion fracture. Journal of Translational Medicine. doi:10.1186/s12967-016-1019-1

LE GOFF, C., Kaux, J.-F., D'OTREPPE DE BOUVETTE, S., Goffaux, S., Fillet, M., Chapelle, J.-P., & Cavalier, E. (August 2016). Release of cardiac biomarkers during a cycling race. World Journal of Cardiovascular Diseases, 6 (8), 285-294.

Houbart, V., COBRAIVILLE, G., Nys, G., Servais, A.-C., & Fillet, M. (May 2016). Volumetric Absorptive Microsampling for Hepcidin Peptide Extraction from Whole Blood. LC GC North America, 34 (5).

HANNON, M., BEGUIN, Y., Ehx, G., SERVAIS, S., SEIDEL, L., Graux, C., Maertens, J., Kerre, T., Daulne, C., de Bock, M., Fillet, M., ORY, A., WILLEMS, E., GOTHOT, A., Humblet-Baron, S., & BARON, F. (15 July 2015). Immune Recovery after Allogeneic Hematopoietic Stem Cell Transplantation following Flu-TBI versus TLI-ATG Conditioning. Clinical Cancer Research, 21 (14), 3131-9. doi:10.1158/1078-0432.CCR-14-3374

Deroyer, C., Magne, J., Moonen, M., Le Goff, C., Dupont, L., Hulin, A., Radermecker, M., Colige, A., Cavalier, E., Kolh, P., Pierard, L., LANCELLOTTI, P., Merville, M.-P., & Fillet, M. (2015). New biomarkers for primary mitral regurgitation. Clinical Proteomics, 12, 25. doi:10.1186/s12014-015-9097-2

Fillet, M., & Frederich, M. (2015). The emergence of metabolomics as a key discipline in the drug discovery process. Drug Discovery Today. Technologies, 13, 19-24. doi:10.1016/j.ddtec.2015.01.006

Lamalle, C., Servais, A.-C., RADERMECKER, R., Crommen, J., & Fillet, M. (2015). Simultaneous determination of insulin and its analogues in pharmaceutical formulations by micellar electrokinetic chromatography. Journal of Pharmaceutical and Biomedical Analysis. doi:10.1016/j.jpba.2014.12.038

LE GOFF, C., Kaux, J.-F., Fillet, M., MELON, P., & Cavalier, E. (April 2014). Two biomarkers for the screening of cardiac risk among runners ? British Journal of Sports Medicine, 48 (7), 174.

LE GOFF, C., Kaux, J.-F., Fillet, M., MELON, P., & Cavalier, E. (April 2014). Cardiac troponins and natriuretic peptides in runners: useful for cardiac risk screening ? British Journal of Sports Medicine, 48 (7), 173. doi:10.1136/bjsports-2014-093494.173

Deroyer, C., Renert, A.-F., Merville, M.-P., & Fillet, M. (2014). New role for Emerin, a key inner nuclear membrane protein, as an enhancer of the autophagosome formation in the C16-ceramide autophagy pathway. Autophagy. doi:10.4161/auto.28777

Fettweis, G., Coupienne, I., Fillet, M., & Piette, J. (04 September 2013). Role of RIP3 in PDT-induced glioblastoma Cell Death [Poster presentation]. 15th Congress of the European Society for Photobiology, Liège, Belgium.

LE GOFF, C., Kaux, J.-F., MELON, P., Fillet, M., CHAPELLE, J.-P., & Cavalier, E. (September 2013). Running races: study of the stress and cardiac biomarkers. European Journal of Sports Medicine, 1 (Supplement 1), 212.

Lamalle, C., Sacre, P.-Y., Marini Djang'Eing'A, R., Servais, A.-C., Hubert, P., Fillet, M., & Crommen, J. (June 2013). ANALYTICAL STRATEGIES FOR THE DETECTION AND CHARACTERIZATION OF COUNTERFEIT MEDICINES [Paper presentation]. 24th Symposium on Pharmaceutical and Biomedical Analysis (PBA2013) / RDPA 2013, Bologna, Italy.

LE GOFF, C., MELON, P., BREVERS, E., Fillet, M., Kaux, J.-F., Chapelle, J.-P., & Cavalier, E. (2013). Comparison of the Heart-type fatty acid-binding protein (H-FABP) with the high sensitive cardiac troponin T in healthy runners. In Book of abstracts of 18th Annual Congress of the ECSS (pp. 465).

LE GOFF, C., Kaux, J.-F., BREVERS, E., Fillet, M., MELON, P., CHAPELLE, J.-P., & Cavalier, E. (May 2013). Comparison of the Heart-type fatty acid-binding protein (H-FABP) with the high sensitive cardiac troponin T in healthy runners. Biochimica Clinica, 37 (SS), 544.

LE GOFF, C., Kaux, J.-F., MELON, P., Fillet, M., CHAPELLE, J.-P., & Cavalier, E. (May 2013). Race Cycling: biological evolution. Biochimica Clinica, 37 (SS), 544.

LE GOFF, C., MELON, P., Kaux, J.-F., Fillet, M., CHAPELLE, J.-P., & Cavalier, E. (May 2013). Impact of strenuous exercise on the release of cardiac biomarkers. Biochimica Clinica, 37 (SS), 545.

De Bock, M., Fillet, M., Hannon, M., Seidel, L., Merville, M.-P., Gothot, A., Beguin, Y., & Baron, F. (2013). Kinetics of IL-7 and IL-15 Levels after Allogeneic Peripheral Blood Stem Cell Transplantation following Nonmyeloablative Conditioning. PLoS ONE, 8 (2), 55876. doi:10.1371/journal.pone.0055876

Knaepen, L., Rayen, I., Charlier, T., Fillet, M., Houbart, V., van Kleef, M., Steinbusch, H. W., Patijn, J., Tibboel, D., Joosten, E. A., & Pawluski, J. (2013). Developmental fluoxetine exposure normalizes the long-term effects of maternal stress on post-operative pain in Sprague-Dawley rat offspring. PLoS ONE, 8 (2), 57608. doi:10.1371/journal.pone.0057608

Kohn, G., Delvaux, D., Lakaye, B., Servais, A.-C., Scholer, G., Fillet, M., Elias, B., Derochette, J.-M., Crommen, J., Wins, P., & Bettendorff, L. (12 September 2012). High inorganic triphosphatase activities in bacteria and mammalian cells: Identification of the enzymes involved. PLoS ONE, 7 (9), 43879. doi:10.1371/journal.pone.0043879

Grammenos, A., Fillet, M., Collodoro, M., Lecart, S., Quoilin, C., Fontaine-Aupart, M.-P., & Hoebeke, M. (2012). An ESR, Mass Spectrometry and Fluorescence microscopy approach to study the stearic acid derivatives anchoring in cells. Applied Magnetic Resonance. doi:10.1007/s00723-012-0375-0

LE GOFF, C., Kaux, J.-F., Goffaux, S., MELON, P., Fillet, M., & Chapelle, J.-P. (2012). Biological variations during a race cycling. In Biomedica 2012 (pp. 157).

Nesseim, T. D. T., Fillet, M., Mergeai, G., Dieng, A., & Hornick, J.-L. (2012). Principes toxiques, toxicité et technologie de détoxification de la graine de Jatropha curcas L. (synthèse bibliographique). Biotechnologie, Agronomie, Société et Environnement, 16 (4), 531-540.

Marini Djang'Eing'A, R., Mbinze Kindenge, J., Debrus, B., Lebrun, P., Mantanus, J., Ziemons, E., Lamalle, C., Fillet, M., Rudaz, S., & Hubert, P. (September 2011). IMPLEMENTATION OF GENERIC ANALYTICAL METHODS TO FIGHT AGAINST COUNTERFEIT MEDICINES [Paper presentation]. Recent Development in Pharmaceutical Analysis (RDPA), Pavia, Italy.

DE SENY, D., Sharif, M., Fillet, M., COBRAIVILLE, G., Meuwis, M.-A., Marée, R., HAUZEUR, J.-P., Wehenkel, L., Louis, E., Merville, M.-P., Kirwan, J., Ribbens, C., & Malaise, M. (2011). Discovery and biochemical characterisation of four novel biomarkers for osteoarthritis. Annals of the Rheumatic Diseases, 70 (6), 1144-52. doi:10.1136/ard.2010.135541

Quesada Calvo, F.* , Fillet, M.* , Renaut, J., Crahay, C., Guéders, M., Hacha, J., Paulissen, G., Foidart, J.-M., Noël, A., Rocks, N., Leprince, P., & Cataldo, D. (2011). Potential Therapeutic Target Discovery by 2D-DIGE Proteomic Analysis in Mouse Models of Asthma. Journal of Proteome Research, 10 (9), 4291-4301. doi:10.1021/pr200494n
* These authors have contributed equally to this work.

Keutgens, A., Shostak, K., Close, P., Zhang-Shao, X., Hennuy, B., Aussems, M., Chapelle, J.-P., Viatour, P., Gothot, A., Fillet, M., & Chariot, A. (August 2010). The repressing function of the oncoprotein BCL-3 requires CtBP while its polyubiquitination and degradation involve the E3 ligase TBLR1. Molecular and Cellular Biology, 30, 4006-4021. doi:10.1128/MCB.01600-09

Le Goff, C., Garweg, C., Laurent, T., Kaux, J.-F., Deroyer, C., Merville, M.-P., Melon, P., Fillet, M., Legrand, V., & Chapelle, J.-P. (July 2010). Assessment of high sensitive troponin T and I immunoassays in patients with acute chest. Clinical Chemistry, 56 (S6), 127.

Le Goff, C., Laurent, T., Garweg, C., Kaux, J.-F., Deroyer, C., Fillet, M., Lancellotti, P., Pierard, L., & Chapelle, J.-P. (July 2010). Does echocardiographic stress test induced release of hsTnT and TnI II? Clinical Chemistry, 56 (S6), 128.

Hubert, C., Houari, S., Lecomte, F., Houbart, V., De Bleye, C., Fillet, M., Piel, G., Rozet, E., & Hubert, P. (26 January 2010). Développement et validation d'une méthode de dosage de la glucosamine par SPE/LC/MS dans le plamsa canin [Paper presentation]. Forum des jeunes chercheurs du C.I.R.M, Liège, Belgium.

Hubert, C., Houari, S., Lecomte, F., Houbart, V., De Bleye, C., Fillet, M., Piel, G., Rozet, E., & Hubert, P. (01 December 2009). Développement et validation d'une méthode de dosage de la glucosamine par SPE/HILIC/MS dans le plamsa de chien [Poster presentation]. 8ème congrès francophone de l'AfSep sur les sciences séparatives et les couplages, Marseille, France.

Hubert, C., Houari, S., Houbart, V., De Bleye, C., Fillet, M., Rozet, E., & Hubert, P. (June 2009). Development and validation of a sensitive SPE/LC/MS method for the determination of glucosamine in dog plasma [Poster presentation]. 34th International Symposium on High Performance Liquid Phase Separations and Related Techniques, Dresden, Germany.

De Bock, M., De Seny, D., Meuwis, M.-A., Chapelle, J.-P., Louis, E., Malaise, M., Merville, M.-P., & Fillet, M. (2009). Challenges for Biomarker Discovery in Body Fluids Using SELDI-TOF-MS. Journal of Biomedicine and Biotechnology. doi:10.1155/2010/906082

De Seny, D., Ribbens, C., Cobraiville, G., Meuwis, M.-A., Marée, R., Geurts, P., Wehenkel, L., Louis, E., Merville, M.-P., Fillet, M., & Malaise, M. (2009). Protéomique par SELDI-TOF-MS des maladies inflammatoires articulaires: identification des protéines S100 comme protéines d'intérêt. Revue Médicale de Liège, 64 (Spec No), 29-35.

Quesada Calvo, F.* , Fillet, M.* , De Seny, D., Meuwis, M.-A., Marée, R., Crahay, C., Paulissen, G., Rocks, N., Guéders, M., Wehenkel, L., Merville, M.-P., Louis, R., Foidart, J.-M., Noël, A., & Cataldo, D. (2009). Biomarker discovery in asthma-related inflammation and remodeling. Proteomics, 9 (8), 2163-2170. doi:10.1002/pmic.200800643
* These authors have contributed equally to this work.

Meuwis, M.-A.* , Fillet, M.* , Lutteri, L., Marée, R., Geurts, P., De Seny, D., Malaise, M., Chapelle, J.-P., Wehenkel, L., Belaiche, J., Merville, M.-P., & Louis, E. (2008). Proteomics for prediction and characterization of response to infliximab in Crohn's disease: a pilot study. Clinical Biochemistry, 41 (12), 960-7. doi:10.1016/j.clinbiochem.2008.04.021
* These authors have contributed equally to this work.

Rousseau, A., Chiap, P., Ivanyi, R., Crommen, J., Fillet, M., & Servais, A.-C. (2008). Validation of a nonaqueous capillary electrophoretic method for the enantiomeric purity determination of R-flurbiprofen using a single-isomer amino cyclodextrin derivative. Journal of Chromatography. A, 1204 (2), 219-225. doi:10.1016/j.chroma.2008.06.006

Mol, R., Servais, A.-C., Fillet, M., Crommen, J., de Jong, G. J., & Somsen, G. W. (03 August 2007). Nonaqueous electrokinetic chromatography-electrospray ionization mass spectrometry using anionic cyclodextrins. Journal of Chromatography. A, 1159 (1-2), 51-57. doi:10.1016/j.chroma.2007.05.050

Marini Djang'Eing'A, R., Servais, A.-C., Rozet, E., Chiap, P., Boulanger, B., Rudaz, S., Crommen, J., Hubert, P., & Fillet, M. (June 2007). Enantiomeric purity testing of S-timolol by non-aqueous CE using heptakis(2,3-di-O-methyl-6-O-Sulfo)-β-cyclodextrin as chiral additive – Validation using the accuracy profile strategy and estimation of uncertainty [Poster presentation]. 31st International Symposium on HPLC and Related techniques, Gand, Belgium.

Martin, G., Chiap, P., Paquet, P., Pierard, G., De Tullio, P., Martin, Y., Rozet, E., Hubert, P., Crommen, J., & Fillet, M. (2007). Development of a mass spectrometry method for the determination of a melanoma biomarker, 5-S-cysteinyldopa, in human plasma using solid phase extraction for sample clean-up. Journal of Chromatography. A, 1156 (1-2), 141-8. doi:10.1016/j.chroma.2006.12.088

Marini Djang'Eing'A, R., Rozet, E., Ziemons, E., Chiap, P., Boulanger, B., Rudaz, S., Servais, A.-C., Fillet, M., Crommen, J., & Hubert, P. (May 2006). COMPARISON OF THREE DIFFERENT APPROACHES FOR UNCERTAINTY ESTIMATION CONSIDERING LC AND CE METHODS [Paper presentation]. A joint meeting of two distinguished series: the 8th International Symposium on Drug Analysis and the 17th International Symposium on Pharmaceutical and Biomedical Analysis, Namur, Belgium.

Servais, A.-C.* , Fillet, M.* , Mol, R., Somsen, G. W., Chiap, P., de Jong, G. J., & Crommen, J. (February 2006). On-line coupling of cyclodextrin mediated nonaqueous capillary electrophoresis to mass spectrometry for the determination of salbutamol enantiomers in urine. Journal of Pharmaceutical and Biomedical Analysis, 40 (3), 752-757. doi:10.1016/j.jpba.2005.08.004
* These authors have contributed equally to this work.

Tokarski, C., Cren-Olive, C., Fillet, M., & Rolando, C. (2006). High-sensitivity staining of proteins for one- and two-dimensional gel electrophoresis using post migration covalent staining with a ruthenium fluorophore. Electrophoresis, 27 (7), 1407-16. doi:10.1002/elps.200500426

Yi, F., Zhang, A. Y., Li, N., Muh, R. W., Fillet, M., Renert, A.-F., & Li, P.-L. (2006). Inhibition of ceramide-redox signaling pathway blocks glomerular injury in hyperhomocysteinemic rats. Kidney International, 70 (1), 88-96. doi:10.1038/

Servais, A.-C., Fillet, M., Chiap, P., Dewé, W., Hubert, P., & Crommen, J. (11 March 2005). Influence of the nature of the electrolyte on the chiral separation of basic compounds in nonaqueous capillary electrophoresis using heptakis(2,3-di-O-methyl-6-O-sulfo)-beta-cyclodextrin. Journal of Chromatography. A, 1068 (1), 143-150. doi:10.1016/j.chroma.2004.12.010

De Seny, D.* , Fillet, M.* , Meuwis, M.-A., Geurts, P., Lutteri, L., Ribbens, C., Bours, V., Wehenkel, L., Piette, J., Malaise, M., & Merville, M.-P. (2005). Discovery of new rheumatoid arthritis biomarkers using the surface-enhanced laser desorption/ionization time-of-flight mass spectrometry ProteinChip approach. Arthritis and Rheumatism, 52 (12), 3801-12. doi:10.1002/art.21607
* These authors have contributed equally to this work.

Fillet, M., Cren-Olive, C., Renert, A.-F., Piette, J., Vandermoere, F., Rolando, C., & Merville, M.-P. (2005). Differential expression of proteins in response to ceramide-mediated stress signal in colon cancer cells by 2-D gel electrophoresis and MALDI-TOF-MS. Journal of Proteome Research, 4 (3), 870-80. doi:10.1021/pr050006t

Geurts, P., Fillet, M., De Seny, D., Meuwis, M.-A., Malaise, M., Merville, M.-P., & Wehenkel, L. (2005). Proteomic mass spectra classification using decision tree based ensemble methods. Bioinformatics, 21 (14), 3138-45. doi:10.1093/bioinformatics/bti494

Olivier, S., Fillet, M., Malaise, M., Piette, J., Bours, V., Merville, M.-P., & Franchimont, N. (2005). Sodium nitroprusside-induced osteoblast apoptosis is mediated by long chain ceramide and is decreased by raloxifene. Biochemical Pharmacology, 69 (6), 891-901. doi:10.1016/j.bcp.2004.11.030

Christians, B., Fillet, M., Chiap, P., Rbeida, O., Ceccato, A., Streel, B., De Graeve, J., Crommen, J., & Hubert, P. (2004). Fully automated method for the liquid chromatographic-tandem mass spectrometric determination of cyproterone acetate in human plasma using restricted access material for on-line sample clean-up. Journal of Chromatography. A, 1056 (1-2), 105-10.

Jans, D., Martinet, W., Fillet, M., Kockx, M. M., Merville, M.-P., Bult, H., Herman, A. G., & De Meyer, G. R. Y. (2004). Effect of non-steroidal anti-inflammatory drugs on amyloid-beta formation and macrophage activation after platelet phagocytosis. Journal of Cardiovascular Pharmacology, 43 (3), 462-70. doi:10.1097/00005344-200403000-00019

Bentires-Alj, M., Barbu, V., Fillet, M., Chariot, A., Relic, B., Jacobs, N., Gielen, J., Merville, M.-P., & Bours, V. (2003). NF-κB transcription factor induces drug resistance through MDR1 expression in cancer cells. Oncogene, 22, 90-97. doi:10.1038/sj.onc.1206056

Fillet, M., Bentires-Alj, M., Deregowski, V., Greimers, R., Gielen, J.-L., Piette, J., Bours, V., & Merville, M.-P. (2003). Mechanisms involved in exogenous C2- and C6-ceramide-induced cancer cell toxicity. Biochemical Pharmacology, 65 (10), 1633-42. doi:10.1016/S0006-2952(03)00125-4

Fillet, M., Van Heugen, J.-C., Servais, A.-C., De Graeve, J., & Crommen, J. (2002). Separation, identification and quantitation of ceramides in human cancer cells by liquid chromatography–electrospray ionization tandem mass spectrometry. Journal of Chromatography. A, 949, 225-233. doi:10.1016/S0021-9673(01)01422-4

Abushoffa, A., Fillet, M., Marini Djang'Eing'A, R., & Crommen, J. (07 April 2000). Separation of aminoglutethimide enantiomers using single and dual cyclodextrin system in capillary electrophoresis [Paper presentation]. 9th Forum of Pharmaceutical Sciences, Blankenberge, Belgium.

Fillet, M., Bechet, I., Fotsing, L., Piette, V., & Crommen, J. (2000). Separation of non-steroidal anti-inflammatory drugs by capillary electrophoresis using non-aqueous electrolyte. Biomedical Chromatography: BMC, 14 (1), 12-3. doi:10.1002/(sici)1099-0801(200002)14:1<12::aid-bmc948>;2-%23

Fotsing, L., Boulanger, B., Chiap, P., Fillet, M., Hubert, P., & Crommen, J. (2000). Multivariate optimization approach for the separation of water-soluble vitamins and related compounds by capillary electrophoresis. Biomedical Chromatography: BMC, 14 (1), 10-1. doi:10.1002/(SICI)1099-0801(200002)14:1<10::AID-BMC947>3.0.CO;2-8

Piette, V., Fillet, M., Lindner, W., & Crommen, J. (2000). Non-aqueous capillary electrophoretic enantioseparation of N-derivatized amino acids using cinchona alkaloids and derivatives as chiral counter-ions. Journal of Chromatography. A, 875 (1-2), 353-60. doi:10.1016/S0021-9673(00)00083-2

Piette, V., Fillet, M., Lindner, W., & Crommen, J. (2000). Enantiomeric separation of amino acid derivatives by non-aqueous capillary electrophoresis using quinine and related compounds as chiral additives. Biomedical Chromatography: BMC, 14 (1), 19-21. doi:10.1002/(SICI)1099-0801(200002)14:1<19::AID-BMC951>3.0.CO;2-Z

Fillet, M., Bechet, I., Piette, V., & Crommen, J. (1999). Separation of nonsteroidal anti-inflammatory drugs by capillary electrophoresis using nonaqueous electrolytes. Electrophoresis, 20 (9), 1907-15. doi:10.1002/(SICI)1522-2683(19990701)20:9<1907::AID-ELPS1907>3.0.CO;2-L

Fillet, M., Chankvetadze, B., Crommen, J., & Blaschke, G. (1999). Designed combination of chiral selectors for adjustment of enantioseparation selectivity in capillary electrophoresis. Electrophoresis, 20 (13), 2691-7. doi:10.1002/(SICI)1522-2683(19990901)20:13<2691::AID-ELPS2691>3.0.CO;2-S

Fotsing, L., Fillet, M., Chiap, P., Hubert, P., & Crommen, J. (1999). Elimination of adsorption effects in the analysis of water-soluble vitamins in pharmaceutical formulations by capillary electrophoresis. Journal of Chromatography. A, 853 (1-2), 391-401. doi:10.1016/S0021-9673(99)00524-5

Fillet, M., Fotsing, L., Bonnard, J., & Crommen, J. (1998). Stereoselective determination of S-naproxen in tablets by capillary electrophoresis. Journal of Pharmaceutical and Biomedical Analysis, 18 (4-5), 799-805. doi:10.1016/S0731-7085(98)00218-0

Fillet, M., Hubert, P., & Crommen, J. (1997). Enantioseparation of nonsteroidal anti-inflammatory drugs by capillary electrophoresis using mixtures of anionic and uncharged beta-cyclodextrins as chiral additives. Electrophoresis, 18 (6), 1013-8. doi:10.1002/elps.1150180625

Bechet, I., Hubert, P., Crommen, J., & Fillet, M. (April 1995). Quantitative Analysis of Non-Steroidal Anti-Inflammatory Drugs by Capillary Zone Electrophoresis. Journal of Pharmaceutical and Biomedical Analysis, 13 (4-5), 497-503. doi:10.1016/0731-7085(95)01339-M