Publications and communications of Michel Moutschen

El Moussaoui, M., Bontems, S., Meex, C., Hayette, M.-P., LEJEUNE, M., Hong, S. L., Dellicour, S., Moutschen, M., CAMBISANO, N., Renotte, N., Bours, V., Darcis, G., Artesi, M.* , & Durkin, K.*. (2024). Intrahost evolution leading to distinct lineages in the upper and lower respiratory tracts during SARS-CoV-2 prolonged infection. medRxiv preprint. doi:10.1101/2024.03.03.24303157

Adawaye, C., Fokam, J., Kamangu, E. N., Ngwese, D. T. A., SUSIN, F., Moussa, A. M., Hig-Zounet, B., Mad-Toingué, J., Tidjani, A., VAIRA, D., & Moutschen, M. (2024). Performance characteristics of Allele-Specific PCR (ASPCR) in detecting drug resistance mutations among non-B HIV-1 Variants. Journal of Virological Methods, 323, 114856. doi:10.1016/j.jviromet.2023.114856

Ebo, D. G., Van der Poorten, M. M., Van Gasse, A. L., Schrijvers, R., Hermans, C., Bartiaux, M., Haerynck, F., Willekens, J., Lapeere, H., Moutschen, M., Michel, O., & Sabato, V. (December 2023). Clinical practice of hereditary angioedema in Belgium: opportunities for optimized care. Acta Clinica Belgica, 78 (6), 431 - 437. doi:10.1080/17843286.2023.2213491

Misset, B., Piagnerelli, M., Hoste, E., Dardenne, N., Grimaldi, D., Michaux, I., De Waele, E., Dumoulin, A., Jorens, P. G., van der Hauwaert, E., Vallot, F., Lamote, S., Swinnen, W., De Schryver, N., Fraipont, V., de Mey, N., Dauby, N., Layios, N., Mesland, J.-B., ... Laterre, P.-F. (26 October 2023). Convalescent Plasma for Covid-19–Induced ARDS in Mechanically Ventilated Patients. New England Journal of Medicine, 389 (17), 1590-1600. doi:10.1056/nejmoa2209502

Misset, B., Nguyet, A. D., BERTRAND, A., Piagnerelli, M., Hoste, E., de Waele, E., Dumoulin, A., Jorens, P., van der Hauwaert, E., Vallot, F., Swinnen, W., De Schryver, N., de Mey, N., Layios, N., Mesland, J., Robinet, S., Cavalier, E., Donneau, A.-F., Moutschen, M., & Laterre, P. F. (24 October 2023). Immunological sub-phenotypes and response to Convalescent-Plasma (CP) in COVID-19 induced ARDS (C-ARDS): a hierarchical cluster analysis [Poster presentation]. ESICM LIVES 2023, Milan, Italy.

Martinez, E., Crevecoeur, S., THIRION, C., GRANDJEAN, J., Fall, P. A., Hayette, M.-P., Moutschen, M., Taminiau, B., Louis, E., & Daube, G. (10 October 2023). Gut Microbiota Associated with Clostridioides difficile Carriage in Three Clinical Groups (Inflammatory Bowel Disease, C. difficile Infection and Healthcare Workers) in Hospital Field. Microorganisms, 11 (10), 2527. doi:10.3390/microorganisms11102527

COVID-19 Host Genetics Initiative, Rahmouni, S., Georges, M., Moutschen, M., Darcis, G., & Beguin, Y. (September 2023). A second update on mapping the human genetic architecture of COVID-19. Nature, 621 (7977), 7 - E26. doi:10.1038/s41586-023-06355-3

Kayembe Ntumba, H. C., Bompangue, D., Linard, C., Mandja, B.-A., Batumbo, D., Matunga, M., Muwonga, J., Moutschen, M., Situakibanza, H., & Ozer, P. (28 August 2023). Drivers of the dynamics of the spread of cholera in the Democratic Republic of the Congo, 2000-2018: An eco-epidemiological study. PLoS Neglected Tropical Diseases, 17 (8), 0011597. doi:10.1371/journal.pntd.0011597

Misset, B., Piagnerelli, M., Hoste, E., Dardenne, N., Grimaldi, D., Michaux, I., De Waele, E., Dumoulin, A., Jorens, P., Layios, N., Moutschen, M., Desmecht, D., Gothot, A., & Laterre, P. F. (14 June 2023). Proceedings of Reanimation 2023, the French Intensive Care Society International CongressCO‐59 Secondary outcomes of the CONFIDENT randomized trial of convalescent plasma therapy with high titers of neutralizing antibodies (NAb) in COVID-ARDS patients [Poster presentation]. SRLF annual meeting 2023, Paris, France. doi:10.1186/s13613-023-01131-y

Burniat, A., Noël, A., Colige, A., Vanderplasschen, A., de Kerchove d'Exaerde, A., Kupper Cardozo, A., Van Keymeulen, A., Moens, A., Bondue, A., Herpain, A., Marchant, A., Loumaye, A., Beck, B., Van den Heyden, B., Corvilain, B., Lakaye, B., Rogister, B., Malgrange, B., Michiels, C., ... Brunko, E. (2023). Cent scientifiques répliquent à SEA (Suppression des Expériences sur l’Animal vivant) et dénoncent sa désinformation. La Libre Belgique.

Amand, M., Adams, P., Schober, R., Iserentant, G., Servais, J.-Y., Moutschen, M., & Seguin-Devaux, C. (2023). The anti-caspase 1 inhibitor VX-765 reduces immune activation, CD4+ T cell depletion, viral load, and total HIV-1 DNA in HIV-1 infected humanized mice. eLife, 12 (February), 83207. doi:10.7554/eLife.83207

El Moussaoui, M., Desmecht, S., Lambert, N., Maes, N., Braghini, J., MARECHAL, N., Quintana, C., BRIQUET, K., Gofflot, S., Toussaint, F., Hayette, M.-P., Vermeersch, P., Lutteri, L., GREGOIRE, C., Beguin, Y., Rahmouni, S., Moutschen, M., Desmecht, D., & Darcis, G. (2023). Cluster Analysis Identifies Distinct Patterns of T-Cell and Humoral Immune Responses Evolution Following a Third Dose of SARS-CoV-2 Vaccine in People Living with HIV. Viruses, 15, 1435. doi:10.3390/v15071435

Mayasi Ngongo, N., Kamangu Ntambwe, E., Situakibanza Nani-Tuma, H., Mbula Mambimbi, M., Mandina Ndona, M., Longokolo Mashi, M., Bepouka Izizag, B., Lukiana, T., Odio Ossam, J., Mangala Sonzi, D., Maes, N., Moutschen, M., El Moussaoui, M., & Darcis, G. (2023). Human Immunodeficiency Virus Viral Load Monitoring and Rate of Virologic Suppression Among Patients Receiving Antiretroviral Therapy in Democratic Republic of the Congo, 2013-2020. Open Forum Infectious Diseases, 10 (6), 2-7. doi:10.1093/ofid/ofad242

Schober, R., Brandus, B., Laeremans, T., Iserentant, G., Rolin, C., Dessilly, G., Zimmer, J., Moutschen, M., Aerts, J. L., Dervillez, X., & Seguin-Devaux, C. (2023). Multimeric immunotherapeutic complexes activating natural killer cells towards HIV-1 cure. Journal of Translational Medicine, 21 (1), 791. doi:10.1186/s12967-023-04669-4

Van der Poorten, M. M., Schrijvers, R., Hermans, C., Bartiaux, M., Haerynck, F., Lapeere, H., Moutschen, M., Michel, O., Sabato, V., Ebo, D. G., & Van Gasse, A. L. (2023). Hereditary angioedema (HAE) in Belgium: results from a national survey. Frontiers in Allergy, 4, 1143897. doi:10.3389/falgy.2023.1143897

Zono, B., Sacheli, R., Nani-Tuma, H. S., Mavanga, A., Mwambi, J. A., Etondo, M., Kasumba, D. M., Moutschen, M., Lelo, G. M., & Hayette, M.-P. (20 September 2022). P461 Cryptococcosis screening and isolates characterization in asymptomatic people living with HIV in Kinshasa, DRC [Poster presentation]. ISHAM 2022 Congress. doi:10.1093/mmy/myac072.p461

El Moussaoui, M., Desmecht, S., Tashkeev, A., Lambert, N., Maes, N., Braghini, J., MARECHAL, N., Quintana, C., BRIQUET, K., Gofflot, S., TOUSSAINT, F., Hayette, M.-P., Vermeersch, P., Lutteri, L., Grégoire, C., Beguin, Y., Rahmouni, S., Moutschen, M., Desmecht, D., & Darcis, G. (05 September 2022). Reduced T-cell response following a third dose of SARS-CoV-2 vaccine in infection-naïve people living with HIV. Journal of Infection, 85, 751-755. doi:10.1016/j.jinf.2022.09.006

De Leeuw, E.* , Van Damme, K. F. A.* , Declercq, J.* , Bosteels, C.* , Maes, B., Tavernier, S. J., Detalle, L., Smart, T., Glatt, S., Debeuf, N., Deckers, J., Lameire, S., Vandecasteele, S. J., De Neve, N., Demedts, I. K., Govaerts, E., Knoop, C., Vanhove, K., Moutschen, M., ... Lambrecht, B. N. (09 August 2022). Efficacy and safety of the investigational complement C5 inhibitor zilucoplan in patients hospitalized with COVID-19: an open-label randomized controlled trial. Respiratory Research, 23 (202), 1-11. doi:10.1186/s12931-022-02126-2

Pathak, G. A., Karjalainen, J., Stevens, C., Neale, B. M., Daly, M., Ganna, A., Andrews, S. J., Kanai, M., Cordioli, M., Polimanti, R., Harerimana, N., Pirinen, M., Liao, R. G., Chwialkowska, K., Trankiem, A., Balaconis, M. K., Nguyen, H., Solomonson, M., Veerapen, K., ... Baillie, J. K. (03 August 2022). A first update on mapping the human genetic architecture of COVID-19. Nature, 608, 1-E10. doi:10.1038/s41586-022-04826-7

Maes, N., Rolland, J., Boutin, R., Codet, M., Lecleve, A., Schils, R., THYS, M., Albert, A., Moutschen, M., & Kolh, P. (07 July 2022). Développement et évaluation d’un outil d’aide à la décision clinique pour le suivi des patients hospitalisés pour COVID-19 au CHU de Liège [Paper presentation]. Conférence Francophone en Gestion et Ingénierie des Systèmes Hospitaliers (GISEH), Saint Etienne, France.

Absil, G., SOUGNE, L., LAHRICHI, D., Collins, P., Meuris, C., Moutschen, M., Nikkels, A., & Orban, C. (July 2022). Variole du singe. Revue Médicale de Liège, 77 (7), 452-455.

El Moussaoui, M., Maes, N., Hong, S. L., Lambert, N., Gofflot, S., DELLOT, P., Belhadj, Y., Huynen, P., Hayette, M.-P., Meex, C., Bontems, S., Defêche, J., Godderis, L., Molenberghs, G., Meuris, C., Artesi, M., Durkin, K., Rahmouni, S., GREGOIRE, C., ... DARCIS, G. (14 June 2022). Evaluation of Screening Program and Phylogenetic Analysis of SARS-CoV-2 Infections among Hospital Healthcare Workers in Liège, Belgium. Viruses, 14 (6), 1302. doi:10.3390/v14061302

GREGOIRE, C.* , HUYNEN, P.* , Gofflot, S., Seidel, L., Maes, N., VRANKEN, L., DELCOUR, S., MOUTSCHEN, M., HAYETTE, M.-P., KOLH, P., MELIN, P., & BEGUIN, Y. (13 June 2022). Predictive factors for the presence and long-term persistence of SARS-CoV-2 antibodies in healthcare and university workers. Scientific Reports, 12, 9790. doi:10.1038/s41598-022-13450-4

Misset, B., Piagnerelli Michaël, Hoste Eric, Dardenne, N., Grimaldi D., Michaux, I., Dumoulin, A., Jorens, P., van der Hauwaert, E., de Waele, E., Vallot, F., Lamote, S., Swinnen, W., Fraipont, V., de Mey, N., de Schryver, N., de Wit, S., Layios, N., Mesland, J., ... Laterre, P. F. (June 2022). Convalescent plasma therapy with high titers of neutralizing antibodies to reduce mortality in patients with COVID-19 associated ARDS: the Belgian randomized CONFIDENT trial [Poster presentation]. SIZ Annual Meeting, Bruxelles, Belgium.

Zono, B.* , SACHELI, R.* , Situakibanza Nani-Tuma, H.* , Kabututu Zakayi, P.* , Ka, A.* , Mbula Mambimbi, M.* , Muendele, G.* , BOREUX, R.* , Landu, N.* , Nzanzu Mudogo, C.* , M'Buze, P.-R.* , MOUTSCHEN, M.* , Meyer, W.* , Mvumbi Lelo, G.* , & HAYETTE, M.-P.*. (19 May 2022). Clinical epidemiology and high genetic diversity amongst Cryptococcus spp. isolates infecting people living with HIV in Kinshasa, Democratic Republic of Congo. PLoS ONE, 17 (5), 0267842. doi:10.1371/journal.pone.0267842

HUYNEN, P.* , GREGOIRE, C.* , GOFFLOT, S., SEIDEL, L., MAES, N., VRANKEN, L., DELCOUR, S., MOUTSCHEN, M., HAYETTE, M.-P., KOLH, P., MELIN, P., & BEGUIN, Y. (25 March 2022). Long-term longitudinal evaluation of the prevalence of SARS-CoV-2 antibodies in healthcare and university workers. Scientific Reports, 12 (1), 5156. doi:10.1038/s41598-022-09215-8

Mayasi, N., Situakibanza, H., Mbula, M., Longokolo, M., Maes, N., Bepouka, B., Ossam, J. O., MOUTSCHEN, M., & DARCIS, G. (11 March 2022). Retention in care and predictors of attrition among HIV-infected patients who started antiretroviral therapy in Kinshasa, DRC, before and after the implementation of the ‘treat-all’ strategy. PLOS Global Public Health, 2 (3), 0000259. doi:10.1371/journal.pgph.0000259

Kayembe Ntumba, H. C., Linard, C., Bompangue, D., Muwonga, J., MOUTSCHEN, M., Situakibanza, H., & Ozer, P. (07 February 2022). Modalities and preferred routes of geographic spread of cholera from endemic areas in eastern Democratic Republic of the Congo. PLoS ONE, 17 (2), 0263160. doi:10.1371/journal.pone.0263160

Devos, T., Van Thillo, Q., Compernolle, V., Najdovski, T., Romano, M., Dauby, N., Jadot, L., Leys, M., Maillart, E., Loof, S., Seyler, L., Moonen, M., MOUTSCHEN, M., Van Regenmortel, N., Ariën, K. K., Barbezange, C., Betrains, A., Garigliany, M.-M., Engelen, M. M., ... DAWn-plasma, I. (February 2022). Early high antibody titre convalescent plasma for hospitalised COVID-19 patients: DAWn-plasma. European Respiratory Journal, 59 (2). doi:10.1183/13993003.01724-2021

Cambier, M., Henket, M., Frix, A.-N., Gofflot, S., THYS, M., Tomasetti, S., Peired, A., Struman, I., Rousseau, A.-F., Misset, B., Darcis, G., Moutschen, M., Louis, R., Njock, M.-S., Cavalier, E., & Guiot, J. (2022). Increased KL-6 levels in moderate to severe COVID-19 infection. PLoS ONE, 17 (11), 0273107. doi:10.1371/journal.pone.0273107

Desmecht, S.* , Tashkeev, A.* , El Moussaoui, M., MARECHAL, N., Perée, H., Tokunaga, Y., Fombellida-Lopez, C., Polese, B., Legrand, C., Wéry, M., Mni, M., Fouillien, N., TOUSSAINT, F., Gillet, L., Bureau, F., LUTTERI, L., HAYETTE, M.-P., MOUTSCHEN, M., MEURIS, C., ... DARCIS, G.*. (2022). Kinetics and persistence of the cellular and humoral immune responses to BNT162b2 mRNA vaccine in SARS-CoV-2-naive and -experienced subjects: impact of booster dose and breakthrough infections. Frontiers in Immunology, 13, 863554. doi:10.3389/fimmu.2022.863554

Donneau, A.-F.* , Guillaume, M.* , BOURS, V., Dandoy, M., DARCIS, G., Desmecht, D., Diep, A. N., Fievez, L., Garigliany, M.-M., Gillain, N., Husson, E., Michel, F., MOUTSCHEN, M., Paridans, M., Pétré, B., Sabatel, C., Saegerman, C., Tytgat, A., Gillet, L.* , & Bureau, F.*. (2022). University population-based prospective cohort study of SARS-CoV- 2 infection and immunity (SARSSURV-ULiège): a study protocol. BMJ Open. doi:10.1136/bmjopen-2021-055721

Egg, D., Rump, I. C., Mitsuiki, N., Rojas-Restrepo, J., Maccari, M.-E., Schwab, C., Gabrysch, A., Warnatz, K., Goldacker, S., Patiño, V., Wolff, D., Okada, S., Hayakawa, S., Shikama, Y., Kanda, K., Imai, K., Sotomatsu, M., Kuwashima, M., Kamiya, T., ... Grimbacher, B. (2022). Therapeutic options for CTLA-4 insufficiency. Journal of Allergy and Clinical Immunology, 149 (2), 736 - 746. doi:10.1016/j.jaci.2021.04.039

Lengele, L., Locquet, M., Moutschen, M., Beaudart, C., KAUX, J.-F., Gillain, S., Reginster, J.-Y., & Bruyère, O. (January 2022). Frailty but not sarcopenia nor malnutrition increases the risk of developing COVID-19 in older community-dwelling adults. Aging Clinical and Experimental Research, 34 (1), 223-234. doi:10.1007/s40520-021-01991-z

Lengele, L., Locquet, M., Moutschen, M., Beaudart, C., Kaux, J.-F., Gillain, S., Shadouh, C., Reginster, J.-Y., & Bruyère, O. (2022). Relationships between malnutrition, sarcopenia, and frailty and the incidence of Covid-19 in older adults: data from the sarcophage cohort. Osteoporosis International, 32 (Suppl 1), 50.

Moutschen, M. (2022). Maladies auto-inflammatoires monogéniques : une introduction sur un mode translationnel aux inflammasomopathies. Revue Médicale de Liège, 77 (5-6), 392 - 398.

Scheen, A., Louis, R., & Moutschen, M. (2022). Apexxnar®, vaccin anti-pneumococcique conjugué avec 20 sérotypes. Revue Médicale de Liège, 77 (11), 678 - 683.

Van Beckhoven, D., Serrien, B., Montourcy, M., Verhofstede, C., Van den Bossche, D., Libois, A., De Geyter, D., Martin, T., Van den Eynde, S., Vuylsteke, B., Darcis, G., van Halem, K., Florence, E., Deblonde, J., Ausselet, N. (Other coll.), Delforge, M.-L. (Other coll.), Demeester, R. (Other coll.), De Munter, P. (Other coll.), Goffard, J.-C. (Other coll.), ... Yombi, J.-C. (Other coll.). (2022). Impact of COVID-19 on the Belgian HIV epidemic: slowdown of HIV transmission and testing and adaptation of care. BMC Infectious Diseases, 22 (1), 901. doi:10.1186/s12879-022-07879-1

Kayembe Ntumba, H. C.* , Linard, C.* , Bompangue, D.* , Muwonga, J.* , MOUTSCHEN, M.* , Situakibanza, H.* , & Ozer, P.*. (19 December 2021). The spread of cholera in western Democratic Republic of the Congo is not unidirectional from East–West: a spatiotemporal analysis, 1973–2018. BMC Infectious Diseases, 21 (1), 1261.

Kayembe Ntumba, H. C., Linard, C., Bompangue, D., Muwonga, J., Moutschen, M., Situakibanza, H., & Ozer, P. (19 December 2021). The spread of cholera in western Democratic Republic of the Congo is not unidirectional from East-West: a spatiotemporal analysis, 1973-2018. BMC Infectious Diseases, 21 (1), 1261. doi:10.1186/s12879-021-06986-9

Zono, B., MOUTSCHEN, M., Situakibanza, H., SACHELI, R., Kabututu, P., Mvumbi, G., & HAYETTE, M.-P. (10 December 2021). Comparaison des caractéristiques cliniques et biologiques des PVVIH présentant une méningite à Cryptococcus neoformans versus C. curvatus/C. laurentii [Paper presentation]. Journées scientifiques PNLS/RDC, Kinshasa, Congo - Kinshasa.

Zono, B., SACHELI, R., Situakibanza, H., Kabututu, P., MOUTSCHEN, M., Mvumbi, G., & HAYETTE, M.-P. (10 December 2021). Épidémiologie clinique et caractérisation moléculaire d’isolats de Cryptococcus spp. infectant les PVVIH à Kinshasa, RDC [Paper presentation]. Journées scientifiques PNLS, Kinshasa, Congo - Kinshasa.

Muraille, E., De Kerchove d'Exaerde, A., Drion, P., Vanderplasschen, A., Lambermont, B., Rogister, B., Muylkens, B., Vassart, G., Balthazart, J., Pillot, J., Pastushenko, L., Moutschen, M., LEONARD, P., Naccache, P., Costagliola, S., & Guerin, S. (2021). "Opter pour l'obligation vaccinale est un choix de société". Le Vif. L'Express.

Zono, B., MOUTSCHEN, M., SITUAKIBANZA, H., SACHELI, R., MUENDELE, G., KABUTUTU, P., BIAKABUSWA, A., LANDU, N., MVUMBI, G., & Hayette, M.-P. (15 November 2021). Comparison of clinical and biological characteristics of HIV infected patients presenting Cryptococcus neorformans versus C. curvatus /C. laurentii meningitis. BMC Infectious Diseases, 21 (1), 1-10. doi:10.1186/s12879-021-06849-3

Zono, B., SACHELI, R., Situakibanza, H., Kabututu, P., Mbula, M., Muendele, G., BOREUX, R., Landu, N., Mudogo, C., M'buze, P.-R., Moutschen, M., Mvumbi, G., & Hayette, M.-P. (28 October 2021). Molecular Analysis of Cryptococcus spp. Reveals Species Diversity and Multilocus Sequence Typing Heterogeneity among People Living with HIV in Kinshasa. Journal of Fungi, 7 (916), 42-43. doi:10.3390/jof7110916

Nakanishi, T., Pigazzini, S., Degenhardt, F., Cordioli, M., Butler-Laporte, G., Maya-Miles, D., Nafría-Jiménez, B., Bouysran, Y., Niemi, M., Palom, A., Ellinghaus, D., Khan, A., Martínez-Bueno, M., Rolker, S., Amitano, S., Tato, L. R., Fava, F., Spinner, C. D., Prati, D., ... consortium, C.-H. (October 2021). Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality. Journal of Clinical Investigation, Online ahead of print.. doi:10.1172/JCI152386

Zono, B., MOUTSCHEN, M., Situakibanza, H., Kabututu, P., Mvumbi, G., & Hayette, M.-P. (12 June 2021). Comparison of clinical and biological characteristics of HIV infected patients presenting Cryptococcus neorformans versus C. curvatus /C. laurentii meningitis [Poster presentation]. MYCOLOGY 2021, London - Online, United Kingdom.

Detry, O., MEURISSE, N., Jouret, F., BLETARD, N., Delwaide, J., & Moutschen, M. (February 2021). Immunosuppression Withdrawal After Liver Transplantation for Common Variable Immunodeficiency. Liver Transplantation, 27 (3), 456-458. doi:10.1002/lt.25873

Adams, P., Fievez, V., Schober, R., Amand, M., Iserentant, G., Rutsaert, S., Dessilly, G., Vanham, G., Hedin, F., Cosma, A., Moutschen, M., Vandekerckhove, L., & Seguin-Devaux, C. (2021). CD32+CD4+ memory T cells are enriched for total HIV-1 DNA in tissues from humanized mice. iScience, 24 (1), 101881. doi:10.1016/j.isci.2020.101881

CALMES, D., Graff, S., MAES, N., Frix, A.-N., THYS, M., BONHOMME, O., Berg, J., DEBRUCHE, M., GESTER, F., HENKET, M., PAULUS, V., DUYSINX, B., HEINEN, V., NGUYEN DANG, D., PAULUS, A., QUAEDVLIEG, V., VAILLANT, F., VAN CAUWENBERGE, H., MALAISE, M., ... SCHLEICH, F. (2021). Asthma and COPD Are Not Risk Factors for ICU Stay and Death in Case of SARS-CoV2 Infection. Journal of Allergy and Clinical Immunology: In Practice, 9 (1), 160-169. doi:10.1016/j.jaip.2020.09.044

Chatterjee, A., Wu, G., Primakov, S., Oberije, C., Woodruff, H., Kubben, P., Henry, R., Aries, M. J. H., Beudel, M., Noordzij, P. G., Dormans, T., Gritters van den Oever, N. C., van den Bergh, J. P., Wyers, C. E., Simsek, S., Douma, R., Reidinga, A. C., de Kruif, M. D., GUIOT, J., ... Lambin, P. (2021). Can predicting COVID-19 mortality in a European cohort using only demographic and comorbidity data surpass age-based prediction: An externally validated study. PLoS ONE, 16 (4), 0249920. doi:10.1371/journal.pone.0249920

D'Antonio, M., Nguyen, J. P., Arthur, T. D., Matsui, H., COVID-19 Host Genetics Initiative, D'Antonio-Chronowska, A., Frazer, K. A., & Moutschen, M. (Other coll.). (2021). SARS-CoV-2 susceptibility and COVID-19 disease severity are associated with genetic variants affecting gene expression in a variety of tissues. Cell Reports, 37 (7), 110020. doi:10.1016/j.celrep.2021.110020

GUIOT, J., Vaidyanathan, A., DEPREZ, L., Zerka, F., Danthine, D., Frix, A.-N., THYS, M., HENKET, M., CANIVET, G., Mathieu, S., EFTAXIA, E., Lambin, P., Tsoutzidis, N., Miraglio, B., Walsh, S., Moutschen, M., Louis, R., Meunier, P., Vos, W., ... LOVINFOSSE, P. (2021). Development and Validation of an Automated Radiomic CT Signature for Detecting COVID-19. Diagnostics, 11 (1). doi:10.3390/diagnostics11010041

Jacques, S., Arjomand, A., Perée, H., COLLINS, P., Mayer, A., Lavergne, A., Wéry, M., Mni, M., Hego, A., Thuillier, V., Becker, G., Bahri, M. A., Plenevaux, A., Di Valentin, E., Oury, C., MOUTSCHEN, M., Delvenne, P., Paquot, N., & Rahmouni, S. (2021). Dual‑specificity phosphatase 3 deletion promotes obesity, non‑alcoholic steatohepatitis and hepatocellular carcinoma. Scientific Reports, 11, 5817. doi:10.1038/s41598-021-85089-6

Meuris, C., Kremer, C., Geerinck, A., Locquet, M., Bruyère, O., Defêche, J., Meex, C., Hayette, M.-P., Duchene, L., Dellot, P., Azarzar, S., Maréchal, N., Sauvage, A.-S., Frippiat, F., Giot, J.-B., Léonard, P., Fombellida, K., Moutschen, M., Durkin, K., ... Darcis, G. (2021). Transmission of SARS-CoV-2 After COVID-19 Screening and Mitigation Measures for Primary School Children Attending School in Liège, Belgium. JAMA Network Open, 4 (10), 2128757. doi:10.1001/jamanetworkopen.2021.28757

Misset, B., Hoste, E., Donneau, A.-F., Grimaldi, D., Meyfroidt, G., Moutschen, M., Compernolle, V., Gothot, A., Desmecht, D., Garigliany, M.-M., Najdovski, T., & Laterre, P. F. (2021). Correction to: A multicenter randomized trial to assess the efficacy of CONvalescent plasma therapy in patients with Invasive COVID-19 and acute respiratory failure treated with mechanical ventilation: the CONFIDENT trial protocol (BMC Pulmonary Medicine, (2020), 20, 1, (317), 10.1186/s12890-020-01361-x). BMC Pulmonary Medicine, 21 (1). doi:10.1186/s12890-021-01574-8

Nasreddine, R., Florence, E., Moutschen, M., Yombi, J.-C., Goffard, J.-C., Derdelinckx, I., Lacor, P., Vandekerckhove, L., Messiaen, P., Vandecasteele, S., Delforge, M., De Wit, S., & Belgian Research on AIDS and HIV Consortium (BREACH). (2021). Clinical characteristics and outcomes of COVID-19 in people living with HIV in Belgium: A multicenter, retrospective cohort. Journal of Medical Virology, 93 (5), 2971 - 2978. doi:10.1002/jmv.26828

Ngongo, N. M., Darcis, G., Nanituna, H. S., Mambimbi, M. M., Maes, N., Mashi, M. L., Bepouka Izizag, B., Moutschen, M., & Lepira Bompeka, F. (2021). Longitudinal analysis of sociodemographic, clinical and therapeutic factors of HIV-infected individuals in Kinshasa at antiretroviral therapy initiation during 2006-2017. PLoS ONE, 16 (11), 0259073. doi:10.1371/journal.pone.0259073

Niemi, M., Gazon, H., JUSZCZAK, D., FADEUR, M., CAMBY, S., MEURIS, C., THYS, M., JACQUES, J., HENKET, M., BEGUIN, Y., Rahmouni, S., Lebrun, M., MOUTSCHEN, M., Misset, B., DARCIS, G., GUIOT, J., AZARZAR, S., DELLOT, P., GOFFLOT, S., ... HUYNEN, P. (Other coll.). (2021). Mapping the human genetic architecture of COVID-19. Nature, 600, 472-477. doi:10.1038/s41586-021-03767-x

Plum, P.-E., Darcis, G., & Moutschen, M. (2021). L’arrivée des bithérapies dans le traitement du virus de l’immunodéficience humaine : la fin d’un dogme? Revue Médicale de Liège, 76 (9), 677 - 682.

DARCIS, G., VAIRA, D., & MOUTSCHEN, M. (2020). Impact of coronavirus pandemic and containment measures on HIV diagnosis. Epidemiology and Infection. doi:10.1017/S0950268820001867

Devos, T., Geukens, T., Schauwvlieghe, A., Ariën, K. K., Barbezange, C., Cleeren, M., Compernolle, V., Dauby, N., Desmecht, D., Grimaldi, D., Lambrecht, B. N., Luyten, A., Maes, P., Moutschen, M., Romano, M., Seyler, L., Nevessignsky, M. T., Vandenberghe, K., van Griensven, J., ... Meyfroidt, G. (2020). A randomized, multicentre, open-label phase II proof-of-concept trial investigating the clinical efficacy and safety of the addition of convalescent plasma to the standard of care in patients hospitalized with COVID-19: the Donated Antibodies Working against nCoV (DAWn-Plasma) trial. Trials, 21 (1), 981. doi:10.1186/s13063-020-04876-0

GUIOT, J., HENKET, M., Frix, A.-N., Delvaux, M., DENIS, A., GILTAY, L., THYS, M., GESTER, F., MOUTSCHEN, M., CORHAY, J.-L., LOUIS, R., LAMBERMONT, B. (Other coll.), & MALAISE, O. (Other coll.). (2020). Single-center experience of patients with interstitial lung diseases during the early days of te COVID-19 pandemic. Respiratory Investigation, 58 (6), 437-9. doi:10.1016/j.resinv.2020.08.006

Misset, B., Hoste, E., Donneau, A.-F., Grimaldi, D., Meyfroidt, G., MOUTSCHEN, M., Compernolle, V., GOTHOT, A., Desmecht, D., Garigliany, M.-M., Najdovski, T., & Laterre, P.-F. (2020). A multicenter randomized trial to assess the efficacy of CONvalescent plasma therapy in patients with Invasive COVID-19 and acute respiratory failure treated with mechanical ventilation: the CONFIDENT trial protocol. BMC Pulmonary Medicine. doi:10.1186/s12890-020-01361-x

PIRARD, C., Léonard, P., Plum, P.-E., Struvay, S., & Moutschen, M. (2020). Les dérivés combinés de l'artémisinine : une avancée thérapeutique dans le contrôle du paludisme non compliqué à Plasmodium falciparum. Revue Médicale de Liège, 75 (5-6), 362 - 365.

Scheen, A., & Moutschen, M. (2020). Le point sur les stratégies médicamenteuses contre la COVID-19 : entre espoirs et déceptions. Revue Médicale de Liège, 75 (S1), 162-169.

Wu, G., Yang, P., Xie, Y., Woodruff, H. C., Rao, X., Guiot, J., Frix, A.-N., Louis, R., Moutschen, M., Li, J., Li, J., Yan, C., Du, D., Zhao, S., Ding, Y., Liu, B., Sun, W., Albarello, F., D'Abramo, A., ... Lambin, P. (2020). Development of a Clinical Decision Support System for Severity Risk Prediction and Triage of COVID-19 Patients at Hospital Admission: an International Multicenter Study. European Respiratory Journal. doi:10.1183/13993003.01104-2020

Mina, M., MOUTSCHEN, M., & MEURIS, C. (13 December 2019). Clinical case : chronic granulomatous disease [Paper presentation]. Annual Congress of the Belgian Society of Internal Medicine, Bruxelles, Belgium.

Eron, J. J., Orkin, C., Cunningham, D., Pulido, F., Post, F. A., De Wit, S., Lathouwers, E., Hufkens, V., Jezorwski, J., Petrovic, R., Brown, K., Van Landuyt, E., Opsomer, M., EMERALD study group, & Moutschen, M. (Other coll.). (2019). Week 96 efficacy and safety results of the phase 3, randomized EMERALD trial to evaluate switching from boosted-protease inhibitors plus emtricitabine/tenofovir disoproxil fumarate regimens to the once daily, single-tablet regimen of darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) in treatment-experienced, virologically-suppressed adults living with HIV-1. Antiviral Research, 170, 104543. doi:10.1016/j.antiviral.2019.104543

Farhat, K., Bodart, G., Moutschen, M., Salvatori, R., Martens, H., & Geenen, V. (December 2018). Growth hormone (GH) deficient mice with GHRH ablation are severely deficient in vaccine and immune responses against Streptococcus pneumoniae. Acta Clinica Belgica, 73 (6 (Suppl.2)).

Farhat, K., Bodart, G., Charlet-Renard, J. D. C., Desmet, C., Moutschen, M., Beguin, Y., Baron, F., Melin, P., Quatresooz, P., Parent, A.-S., Desmecht, D., Sirard, J.-C., Salvatori, R., Martens, H., & Geenen, V. (02 October 2018). Growth hormone (GH) deficient mice with GHRH ablation are severely deficient in vaccine and immune responses against Streptococcus pneumoniae. Frontiers in Immunology, 9, 2175. doi:10.3389/fimmu.2018.02175

DARCIS, G., Lambert, I., SAUVAGE, A.-S., FRIPPIAT, F., MEURIS, C., UURLINGS, F., LECOMTE, M., LEONARD, P., GIOT, J.-B., fombellida, K., VAIRA, D., & MOUTSCHEN, M. (2018). Factors associated with late presentation for HIV care in a single Belgian reference center: 2006-2017. Scientific Reports. doi:10.1038/s41598-018-26852-0

De Benedetti, F., Gattorno, M., Anton, J., Ben-Chetrit, E., Frenkel, J., Hoffman, H. M., Kone-Paut, I., Lachmann, H. J., Ozen, S., Simon, A., Zeft, A., Calvo Penades, I., Moutschen, M., Quartier, P., Kasapcopur, O., Shcherbina, A., Hofer, M., Hashkes, P. J., Van der Hilst, J., ... Junge, G. (2018). Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes. New England Journal of Medicine, 378 (20), 1908-1919. doi:10.1056/NEJMoa1706314

De Wit, S., Florence, E., Vandekerckhove, L., Vandercam, B., Goffard, J.-C., Van Wijngaerden, E., Moutschen, M., Demeester, R., Thilakarathne, P., Piryns, H., & for the BREACH* Consortium. (2018). Long-term use of darunavir/ritonavir-containing regimens in daily practice in Belgium: retrospective observational cohort data of 1701 HIV-patients. Acta Clinica Belgica, 1-7. doi:10.1080/17843286.2018.1458428

de Worm, S., GIOT, J.-B., Courtoy, C., Gillet, E., Amrane, S., Huynen, P., Van Esbroeck, M., Prudent, E., Lepidi, H., Million, M., Moutschen, M., & Raoult, D. (2018). A case of giant cell arteritis associated with culture-proven Coxiella burnetii aortitis. International Journal of Infectious Diseases, 69, 50-54. doi:10.1016/j.ijid.2018.01.028

Egg, D., Schwab, C., Gabrysch, A., Arkwright, P. D., Cheesman, E., Giulino-Roth, L., Neth, O., Snapper, S., Okada, S., Moutschen, M., Delvenne, P., Pecher, A.-C., Wolff, D., Kim, Y.-J., Seneviratne, S., Kim, K.-M., Kang, J.-M., Ojaimi, S., McLean, C., ... Grimbacher, B. (2018). Increased risk for malignancies in 131 affected CTLA4 mutation carriers. Frontiers in Immunology, 9 (SEP). doi:10.3389/fimmu.2018.02012

DE VOEGHT, A., Martens, H., RENARD, J. D. C., VAIRA, D., Debruche, M., Simonet, J., Geenen, V., MOUTSCHEN, M., & DARCIS, G. (2017). Exploring the link between innate immune activation and thymic function by measuring sCD14 and TRECs in HIV patients living in Belgium. PLoS ONE. doi:10.1371/journal.pone.0185761

Vandereyken, M., Jacques, S., Van Overmeire, E., Amand, M., Rocks, N., Delierneux, C., Singh, P., Singh, M., GHUYSEN, C., Wathieu, C., Zurashvili, T., Sounni, N. E., Moutschen, M., Gilles, C., Oury, C., Cataldo, D., Van Ginderachter, J. A., & Rahmouni, S. (2017). Dusp3 deletion in mice promotes experimental lung tumour metastasis in a macrophage dependent manner. PLoS ONE. doi:10.1371/journal.pone.0185786

DARCIS, G., Van der Auwera, G., GIOT, J.-B., Hayette, M.-P., Tassin, F., Arrese Estrada, J., Cnops, L., Moutschen, M., de Leval, L., & LEONARD, P. (07 July 2017). Recurrence of visceral and muco-cutaneous leishmaniasis in a patient under immunosuppressive therapy. BMC Infectious Diseases, 17. doi:10.1186/s12879-017-2571-x

Farhat, K., Bodart, G., RENARD, J. D. C., Desmet, C., MOUTSCHEN, M., Beguin, Y., Baron, F., Salvatori, R., Geenen, V., & Martens, H. (23 May 2017). A surprising and dramatic neuroendocrine-immune phenotype of mice deficient in Growth Hormone-Releasing Hormone (GHRH) [Poster presentation]. European Congress of Endocrinology, Lisbonne, Portugal. doi:10.1530/endoabs.49.EP883

Farhat, K., Bodart, G., Renard, C., Desmet, C., MOUTSCHEN, M., BARON, F., Beguin, Y., Salvatori, R., Martens, H., & GEENEN, V. (May 2017). A surprising and dramatic neuroendocrine-immune phenotype of mice deficient in Growth Hormone-Releasing Hormone (GHRH) [Poster presentation]. The 19th European Congress of Endocrinology, Lisbon, Portugal.

HUART, J., GROSCH, S., BOVY, C., Moutschen, M., & Krzesinski, J.-M. (April 2017). IgG4-related membranous glomerulonephritis and generalized lymphadenopathy without pancreatitis: a case report. BMC Nephrology, 18, 139. doi:10.1186/s12882-017-0561-2

Adawaye, C., Fokam, J., Kamangu, E., Alio, H. M., Chahad, A. M., SUSIN, F., Moussa, A. M., Bertin, T. H. Z., Tidjani, A., VAIRA, D., & Moutschen, M. (2017). Virological response, HIV-1 drug resistance mutations and genetic diversity among patients on first-line antiretroviral therapy in N'Djamena, Chad: Findings from a cross-sectional study. BMC Research Notes, 10 (1). doi:10.1186/s13104-017-2893-1

Deleixhe, B., FRIPPIAT, F., Léonard, P., WITHOFS, N., MEEX, C., Pierard, L., & Moutschen, M. (2017). Endocardite à aggregatibacter aphrophilus sur prothèses valvulaires. Revue Médicale de Liège, 72 (12), 522-528.

Vandereyken, M., Singh, P., Wathieu, C., Jacques, S., Zurashvili, T., Dejager, L., Amand, M., Musumeci, L., Singh, M., MOUTSCHEN, M., Libert, C., & Rahmouni, S. (2017). Dual-Specificity Phosphatase Deletion Protects Female, but Not Male, Mice from Endotoxemia- and Polymicrobial-Induced Septic Shock. Journal of Immunology. doi:10.4049/jimmunol.1602092

Vogl, C., Butola, T., Haag, N., Hausrat, T. J., Leitner, M. G., Moutschen, M., Lefèbvre, P., Speckmann, C., Garrett, L., Becker, L., Fuchs, H., Hrabe de Angelis, M., Nietzsche, S., Kessels, M., Oliver, D., Kneussel, M., Kilimann, M. W., & Strenzke, N. (2017). The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing. EMBO Reports, 18 (11), 2015-2029. doi:10.15252/embr.201643689

DE VOEGHT, A., Maes, N., & Moutschen, M. (27 March 2016). sCD14 is not a bona-fide biomarker of microbial translocation in HIV-1 infected Africans living in Belgium. AIDS, 30 (6), 921-4. doi:10.1097/QAD.0000000000000996

DE VOEGHT, A., SAUVAGE, A.-S., GENSBURGER, M., GIOT, J.-B., & Moutschen, M. (2016). Tuberculose miliaire chez une patiente sous adalimumab. Revue Médicale de Liège, 71 (7-8), 328-331.

Durel, C.-A., Aouba, A., Bienvenu, B., Deshayes, S., Coppere, B., Gombert, B., Acquaviva-Bourdain, C., Hachulla, E., Lecomte, F., Touitou, I., Ninet, J., Philit, J.-B., Messer, L., Brouillard, M., Girard-Madoux, M.-H., Moutschen, M., Raison-Peyron, N., Hutin, P., Duffau, P., ... Hot, A. (2016). Observational Study of a French and Belgian Multicenter Cohort of 23 Patients Diagnosed in Adulthood With Mevalonate Kinase Deficiency. Medicine, 95 (11), 3027. doi:10.1097/MD.0000000000003027

Mayaki, Z., Kabo, R., Moutschen, M., Albert, A., Dardenne, N., Sondag, D., & Gérard, C. (2016). Knowledge, attitudes and clinical practice of blood products prescribers in Niamey. Transfusion Clinique et Biologique, 23 (2), 78-85. doi:10.1016/j.tracli.2015.11.007

van der Hilst, J. C., Moutschen, M., Messiaen, P. E., Lauwerys, B. R., & Vanderschueren, S. (2016). Efficacy of anti-IL-1 treatment in familial Mediterranean fever: a systematic review of the literature. Biologics: Targets and Therapy, 10, 75-80. doi:10.2147/BTT.S102954

Vandereyken, M., Amand, M., Van Overmeire, E., Zurashvili, T., MOUTSCHEN, M., Gilles, C., Van Ginderachter, J., & Rahmouni, S. (June 2015). Genetic depletion of the dual specificity protein phosphatase DUSP3 promotes LLC Lung tumour metastasis [Paper presentation]. Europhosphatase 2015: Phosphorylation switches and cellular homeostasis, Turku, Finland.

Vandereyken, M., Amand, M., Van Overmeire, E., Zurashvili, T., MOUTSCHEN, M., Noël, A., Gilles, C., Van Ginderachter, J., & Rahmouni, S. (June 2015). Genetic depletion of the dual specificity protein phosphatase DUSP3 promotes LLC Lung tumour metastasis [Poster presentation]. Europhosphatase 2015: Phosphorylation switches and cellular homeostasis, Turku, Finland.

DARCIS, G., Kula, A., Bouchat, S., Fujinaga, K., Corazza, F., Ait-Ammar, A., Delacourt, N., Melard, A., Kabeya, K., Vanhulle, C., Van Driessche, B., GATOT, J.-S., Cherrier, T., Pianowski, L. F., Gama, L., Schwartz, C., Vila, J., Burny, A., Clumeck, N., ... Van Lint, C. (2015). An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression. PLoS Pathogens, 11 (7), 1005063. doi:10.1371/journal.ppat.1005063

Kouri, V., Khouri, R., Alemán, Y., Abrahantes, Y., Vercauteren, J., Pineda-Peña, A.-C., Theys, K., Megens, S., Moutschen, M., Pfeifer, N., Van Weyenbergh, J., Pérez, A. B., Pérez, J., Pérez, L., Van Laethem, K., & Vandamme, A.-M. (2015). CRF19_cpx is an Evolutionary fit HIV-1 Variant Strongly Associated With Rapid Progression to AIDS in Cuba. EBioMedicine, 2 (3), 244-254. doi:10.1016/j.ebiom.2015.01.015

Van Beckhoven, D., Florence, E., Ruelle, J., Deblonde, J., Verhofstede, C., Callens, S., Vancutsem, E., Lacor, P., Demeester, R., Goffard, J.-C., Sasse, A., De Wit, S., Vogelaers, D., Delforge, M.-L., Florence, E., Fransen, K., Goffard, J.-C., Hayette, M.-P., Lacor, P., ... Verhofstede, C. (2015). Good continuum of HIV care in Belgium despite weaknesses in retention and linkage to care among migrants. BMC Infectious Diseases, 15 (1). doi:10.1186/s12879-015-1230-3

STERGIOPOULOU, T., Walsh, T. J., SEGHAYE, M.-C., Netea, M. G., Casanova, J.-L., MOUTSCHEN, M., & Picard, C. (09 May 2014). Primary deficiency of interleukin-1 receptor-associated kinase (IRAK-4) presenting as fatal pseudomonas aeruginosa bacteremia in two siblings [Poster presentation]. 32nd Annual Meeting of the European Society for Paediatric Infectious Diseases, Dublin, Ireland.

Amand, M., Erpicum, C., BAJOU, K., Cerignoli, F., Blacher, S., Martin, M., Dequiedt, F., Drion, P., Singh, P., Zurashvili, T., Vandereyken, M., Musumeci, L., Mustelin, T., Moutschen, M., Gilles, C., Noël, A., & Rahmouni, S. (2014). DUSP3/VHR is a pro-angiogenic atypical dual-specificity phosphatase. Molecular Cancer. doi:10.1186/1476-4598-13-108

Bonhomme, O., & Moutschen, M. (2014). Diagnostic et traitement des oedèmes angioneurotiques héréditaires: Illustration clinique et brève revue de la littérature. Revue Médicale de Liège, 69 (10), 541 - 548.

Duray, A., Demoulin, S., Petermans, J., Moutschen, M., Saussez, S., Jerusalem, G., & Delvenne, P. (2014). Vieillissement et cancer: coincidence ou relation etiologique? Revue Médicale de Liège, 69 (5-6), 276-81.

Frippiat, F., Seidel, L., Denooz, R., DAMAS, P., Layios, N., & Moutschen, M. (2014). Pharmacokinetics of Extended vs Intermittent Intravenous Infusion of Meropenem in Critically Ill Patients Receiving Continuous Veno-Venous Haemofiltration. Open Forum Infectious Diseases. doi:10.1093/ofid/ofu052

LAYIOS, N., CANIVET, J.-L., Baron, F., Moutschen, M., & Hayette, M.-P. (2014). Mortierella wolfii-Associated Invasive Disease. Emerging Infectious Diseases, 20 (9), 1591-2. doi:10.3201/eid2009.140469

Megens, S., VAIRA, D., De Baets, G., Dekeersmaeker, N., Schrooten, Y., Li, G., Schymkowitz, J., Rousseau, F., Vandamme, A.-M., Moutschen, M., & Van Laethem, K. (2014). Horizontal gene transfer from human host to HIV-1 reverse transcriptase confers drug resistance and partly compensates for replication deficits. Virology, 456-457, 310-8. doi:10.1016/j.virol.2014.03.023

Singh, M., Singh, P., VAIRA, D., Amand, M., Rahmouni, S., & Moutschen, M. (2014). Minocycline attenuates HIV-1 infection and suppresses chronic immune activation in humanized NOD/LtsZ-scidIL-2Rgamma(null) mice. Immunology, 142 (4), 562-72. doi:10.1111/imm.12246

Torres, A., Bonanni, P., Hryniewicz, W., Moutschen, M., Reinert, R. R., & Welte, T. (2014). Pneumococcal vaccination: what have we learnt so far and what can we expect in the future? European Journal of Clinical Microbiology and Infectious Diseases. doi:10.1007/s10096-014-2208-6

ESSER, N., L'Homme, L., DE ROOVER, A., KOHNEN, L., SCHEEN, A., MOUTSCHEN, M., Piette, J., Legrand-Poels, S., & PAQUOT, N. (November 2013). Obesity phenotype is related to NLRP3 inflammasome activity and immunological profile of visceral adipose tissue. Diabetologia, 56, 2487-2497. doi:10.1007/s00125-013-3023-9

Adawaye, C. I., Erick, K., Ali, M. M., Bertin, T., VAIRA, D., & MOUTSCHEN, M. (September 2013). Use of Dried Blood Spot to Improve the Diagnosis and Management of HIV in Resource-Limited Settings. World Journal of AIDS, 3, 251-256. doi:10.4236/WJA.2013.33033

Musumeci, L., Maurissen, L., Kuijpers, M. J., Senis, Y., MOUTSCHEN, M., Mustelin, T., Heemskerk, J. W., Oury, C., & Rahmouni, S. (02 July 2013). Genetic deletion of Vaccinia H1-related (VHR) phosphatase inhibits collagen-induced platelet activation and thrombus formation without affecting bleeding time in mice [Paper presentation]. XXIVth Congress of the ISTH, Amsterdam, Netherlands.

Esser, N., L'Homme, L., DE ROOVER, A., KOHNEN, L., SCHEEN, A., MOUTSCHEN, M., Piette, J., Legrand-Poels, S., & PAQUOT, N. (2013). Increased Inflammasome and Caspase-1 Activation in Visceral adipose tissue from Metabolically Unhealthy Obese compared to Metabolically Healthy Obese subjects. Diabetes, (62/suppl.1), 555.

Rahmouni, S., Singh, P., Dejager, L., Singh, M., Amand, M., Musumeci, L., Moutschen, M., Mustelin, T., & Libert, C. (2013). Dual-specificity phosphatase 3 knockout female mice are resistant to LPS and to polymicrobial induced septic shock in TNF dependent manner. Journal of Immunology.

Esser, N., L'Homme, L., DE ROOVER, A., KOHNEN, L., SCHEEN, A., Moutschen, M., Piette, J., Legrand-Poels, S., & PAQUOT, N. (March 2013). Différences d’activité de l’inflammasome NLRP3 entre sujets obèses avec et sans anomalies métaboliques. Diabetes and Metabolism, 39 (suppl 1), 102.

Esser, N., L'Homme, L., SCHEEN, A., MOUTSCHEN, M., Piette, J., PAQUOT, N., & Legrand, S. (January 2013). Differences in inflammasome activation between metabolically healthy and unhealthy obese individuals [Poster presentation]. Metabolic control of inflammation and immunity, Breckenridge, Colorado, United States.

Pirotte, B., Rassenfosse, M., Collin, R., De Voeght, A., MOUTSCHEN, M., & CAVALIER, E. (2013). Rôle de la vitamine D dans l'infection par le VIH: revue des connaissances actuelles. Revue Médicale de Liège, 68 (1), 25-31.

Singh, M., Singh, P., Gaudray, G., Musumeci, L., Thielen, C., VAIRA, D., Vandergeeten, C., Delacroix, L., Van Gulck, E., Vanham, G., de Leval, L., Rahmouni, S., & MOUTSCHEN, M. (2012). An improved protocol for efficient engraftment in NOD/LTSZ-SCIDIL-2Rgammanull mice allows HIV replication and development of anti-HIV immune responses. PLoS ONE, 7 (6), 38491. doi:10.1371/journal.pone.0038491

Theys, K., Deforche, K., Vercauteren, J., Libin, P., van de Vijver, D. A., Albert, J., Asjo, B., Balotta, C., Bruckova, M., Camacho, R. J., Clotet, B., Coughlan, S., Grossman, Z., Hamouda, O., Horban, A., Korn, K., Kostrikis, L. G., Kucherer, C., Nielsen, C., ... MOUTSCHEN, M. (2012). Treatment-associated polymorphisms in protease are significantly associated with higher viral load and lower CD4 count in newly diagnosed drug-naive HIV-1 infected patients. Retrovirology, 9, 81. doi:10.1186/1742-4690-9-81

Van Beckhoven, D., Buve, A., Ruelle, J., Seyler, L., Sasse, A., & MOUTSCHEN, M. (2012). A national cohort of HIV-infected patients in Belgium: design and main characteristics. Acta Clinica Belgica, 67 (5), 333-7. doi:10.2143/ACB.67.5.2062686

Singh, M., Singh, P., VAIRA, D., Tasken, K., Rahmouni, S., & Moutschen, M. (03 October 2011). Humanized mice as a useful model to study HIV-1 induced immune activation, its mechanisms and potential therapeutic approaches. Retrovirology, 8, 62.

DOUPAGNE, G., Toukouki, A., & Moutschen, M. (2011). Des interactions complexes entre les origines du VIH et sa pandemie, les activites coloniales en Afrique et la medecine coloniale Belge au Congo. Revue Médicale de Liège, 66 (9), 478-84.

FRIPPIAT, F., & Moutschen, M. (2011). Syphilis treatment in the human immunodeficiency virus-infected patient: follow the guidelines. Clinical Infectious Diseases, 53 (8), 845. doi:10.1093/cid/cir513

Mosenden, R.* , Singh, P.* , Cornez, I., Heglind, M., Ruppelt, A., MOUTSCHEN, M., Enerbäck, S., Rahmouni, S., & Tasken, K. (2011). Mice with Disrupted Type I Protein Kinase A Anchoring in T Cells Resist Retrovirus-Induced Immunodeficiency. Journal of Immunology, 186 (9), 5119-30. doi:10.4049/jimmunol.1100003

Moutschen, P., Bourhaba, M., FRIPPIAT, F., GIOT, J.-B., MEURIS, C., Leonard, P., & Moutschen, M. (2011). A pauci-symptomatic case of documented Hantavirus (Puumala) infection in a patient under anti-TNF treatment. Journal of Clinical Virology, 50 (3), 247-8. doi:10.1016/j.jcv.2010.11.016

Geenen, V., Mottet, M., Dardenne, O., Kermani, H., Martens, H., François, J.-M., Galleni, M., Hober, D., Rahmouni, S., & Moutschen, M. (2010). Thymic self-antigens for the design of a negative/tolerogenic self-vaccination against type 1 diabetes. Current Opinion in Pharmacology, 10, 461-472. doi:10.1016/j.coph.2010.04.005

Rahier, J.-F., Moutschen, M., Van Gompel, A., Van Ranst, M., Louis, E., Segaert, S., Masson, P., & De Keyser, F. (2010). Vaccinations in patients with immune-mediated inflammatory diseases. Rheumatology, 49 (10), 1815-27. doi:10.1093/rheumatology/keq183

Vandenbroucke, I., Van Marck, H., Mostmans, W., Van Eygen, V., Rondelez, E., Thys, K., Van Baelen, K., Fransen, K., Vaira, D., Kabeya, K., De Wit, S., Florence, E., Moutschen, M., Vandekerckhove, L., Verhofstede, C., & Stuyver, L. J. (2010). HIV-1 V3 envelope deep sequencing for clinical plasma specimens failing in phenotypic tropism assays. AIDS Research and Therapy, 7, 4. doi:10.1186/1742-6405-7-4

Wu, S.* , Vossius, S.* , Rahmouni, S.* , Miletic, A. V., Vang, T., Vazquez-Rodriguez, J., Cerignoli, F., Arimura, Y., Williams, S., Hayes, T., Moutschen, M., Vasile, S., Pellecchia, M., Mustelin, T., & Tautz, L. (12 November 2009). Multidentate small-molecule inhibitors of vaccinia H1-related (VHR) phosphatase decrease proliferation of cervix cancer cells. Journal of Medicinal Chemistry, 52 (21), 6716-23. doi:10.1021/jm901016k

Garcia, M. V., Mukeba-Tshialala, D., Vaira, D., & Moutschen, M. (2009). Triom une: la tritherapie du pauvre ? Revue Médicale de Liège, 64 (1), 32-6.

Morrhaye, G., Kermani, H., Legros, J.-J., Baron, F., Beguin, Y., Moutschen, M., Cheynier, R., Martens, H., & Geenen, V. (2009). Impact of growth hormone (GH) deficiency and GH replacement upon thymus function in adult patients. PLoS ONE, 4 (5), 5668. doi:10.1371/journal.pone.0005668

Moutschen, M., & Scheen, A. (2009). Bases immunologiques a la comprehension du concept d'anticorps monoclonal. Revue Médicale de Liège, 64 (5-6), 237-43.

Mukeba, D., Chandrikakumari, K., Giot, J.-B., Leonard, P., Meuris, C., Frippiat, F., & Moutschen, M. (2009). Autoimmune angioneurotic edema in a patient with Helicobacter pylori infection. Helicobacter, 14 (1), 9-11. doi:10.1111/j.1523-5378.2009.00651.x

Reuse, S., Calao, M., Kabeya, K., Guiguen, A., GATOT, J.-S., Quivy, V., Vanhulle, C., Lamine, A., Vaira, D., Demonte, D., Martinelli, V., Veithen, E., Cherrier, T., Avettand, V., Poutrel, S., Piette, J., de Launoit, Y., Moutschen, M., Burny, A., ... Van Lint, C. (2009). Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection. PLoS ONE, 4 (6), 6093. doi:10.1371/journal.pone.0006093

Rodger, A. J., Fox, Z., Lundgren, J. D., Kuller, L. H., Boesecke, C., Gey, D., Skoutelis, A., Goetz, M. B., Phillips, A. N., & Moutschen, M. (Other coll.). (2009). Activation and coagulation biomarkers are independent predictors of the development of opportunistic disease in patients with HIV infection. Journal of Infectious Diseases, 200 (6), 973-83. doi:10.1086/605447

Scheen, A., & Moutschen, M. (2009). Les anticorps monoclonaux en thérapeutique. Revue Médicale de Liège, 64 (5-6), 233-6.

Witvrouw, N., Darcis, G., Gaudray, G., Schaaf-Lafontaine, N., Hustinx, R., Meuris, C., Schepers, K., & Moutschen, M. (2009). A 14-day treatment with a cyclooxygenase 2 (COX-2) inhibitor reduces inflammation in the lymphoid tissues of HIV-infected patients without HAART - a pilot study with positron emission tomography (PET/CT) assessment [Paper presentation]. International AIDS Society 2009 Cape Town, South Africa, Cape Town, South Africa.

Cooper, D. A., Steigbigel, R. T., Gatell, J. M., Rockstroh, J. K., Katlama, C., Yeni, P., Lazzarin, A., Clotet, B., Kumar, P. N., Eron, J. E., Schechter, M., Markowitz, M., Loutfy, M. R., Lennox, J. L., Zhao, J., Chen, J., Ryan, D. M., Rhodes, R. R., Killar, J. A., ... Moutschen, M. (2008). Subgroup and resistance analyses of raltegravir for resistant HIV-1 infection. New England Journal of Medicine, 359 (4), 355-65. doi:10.1056/NEJMoa0708978

Nkoghe, D., Moutschen, M., & Demonty, J. (2008). Lesions cerebrales demyelinisantes decouvertes chez un patient immunocompetent VIH-1+. Médecine et Maladies Infectieuses, 38 (9), 500-3. doi:10.1016/j.medmal.2008.06.010

Sokal, E. M., Hoppenbrouwers, K., Vandermeulen, C., Moutschen, M., Leonard, P., Moreels, A., Haumont, M., Bollen, A., Smets, F., & Denis, M. (15 December 2007). Recombinant gp350 vaccine for infectious mononucleosis: A phase 2, randomized, double-blind, placebo-controlled trial to evaluate the safety, immunogenicity, and efficacy of an Epstein-Barr virus vaccine in healthy young adults. Journal of Infectious Diseases, 196 (12), 1749-1753. doi:10.1086/523813

Uurlings, F., & Moutschen, M. (November 2007). Patients infectes par le VIH. Et syndrome lipodystrophique. Revue Médicale de Liège, 62 (11), 669-74.

Mayasi, N., Chandrikakumari, K., Mukeba, D., GIOT, J.-B., Leonard, P., Hayette, M.-P., Moutschen, M., & Frippiat, F. (01 September 2007). A Patient with Hiv Infection, Cough, Asthenia, and Fever. Clinical Infectious Diseases, 45 (5), 662-3, 559-600. doi:10.1086/520656

Castermans, E., Morrhaye, G., Marchand, S., Martens, H., Moutschen, M., Baron, F., Beguin, Y., & Geenen, V. (2007). Evaluation clinique de la fonction du thymus. Revue Médicale de Liège, 62 (11), 675-8.

Castermans, E., Morrhaye, G., Marchand, S., Martens, H., Moutschen, M., Geenen, V., Beguin, Y., & Baron, F. (2007). Evaluation de la thymopoiese: applications cliniques. Revue Médicale de Liège, 62 (12), 725-9.

Chandrika, K., Dellot, P., Frippiat, F., Giot, J.-B., Leonard, P., Marée, R., Mayasi, N., Meuris, C., Mukeba Tshialala, D., Rahmouni, S., Uurlings, F., Vaira, D., Wehenkel, L., Demonty, J., & Moutschen, M. (2007). Nouvelles approches dans la prise en charge de l'infection a VIH. Revue Médicale de Liège, 62 Spec No, 47-50.

GIOT, J.-B., Mukeba Tshialala, D., Mayasi Ngongo, N., Frippiat, F., Leonard, P., & Moutschen, M. (2007). Avancees therapeutiques en pathologie infectieuse au cours de la derniere decennie. Revue Médicale de Liège, 62 (5-6, May-Jun), 377-83.

Zeddou, M., Rahmouni, S., Vandamme, A., Jacobs, N., Frippiat, F., Leonard, P., SCHAAF-LAFONTAINE, N., Vaira, D., Boniver, J., & Moutschen, M. (2007). Downregulation of CD94/NKG2A inhibitory receptors on CD8+ T cells in HIV infection is more pronounced in subjects with detected viral load than in their aviraemic counterparts. Retrovirology, 4, 72. doi:10.1186/1742-4690-4-72

Zeddou, M., Boniver, J., Moutschen, M., & Rahmouni, S. (February 2006). Prostanglandin E2 induces the expression of functional inhibitory CD94/NKG2A receptors in human CD8+ T lymphocytes by a cAMP-dependent protein kinase A type I pathway [Paper presentation]. Keystone Symposia - Innate Immunity, Banff, Canada.

Bourhaba, M., GIOT, J.-B., Tshialala, D. M., Leonard, P., Frippiat, F., & Moutschen, M. (2006). L'Hantavirose fait encore parler d'elle. Revue Médicale de Liège, 61 (5-6, May-Jun), 322-8.

Collette, G., Bourhaba, M., & Moutschen, M. (2006). Doit-on encore recommander le vaccin BCG? Revue Médicale de Liège, 61 (5-6, May-Jun), 430-2.

Zeddou, M., Rahmouni, S., VANDAMME, A., Schaaf-Lafontaine, N., & Moutschen, M. (2006). HIV viraemic patients downregulate CD94/NKG2A inhibitory receptors on NK as well as CD8 T cells in comparison with aviraemic counterparts [Poster presentation]. AIDS 2006 - XVI International AIDS Conference.

Moutschen, M. (2005). Anomalies des cellules de l'immunite naturelle et risque infectieux chez le patient diabetique. Revue Médicale de Liège, 60 (5-6, May-Jun), 541-4.

Derdelinckx, I., Van Laethem, K., Maes, B., Schrooten, Y., De Wit, S. P., Florence, E., Fransen, K., Ribas, S. G., Marissens, D., Moutschen, M., Vaira, D., Zissis, G., Van Ranst, M., Van Wijngaerden, E., & Vandamme, A.-M. (15 December 2004). Current levels of drug resistance among therapy-naive HIV-infected patients have significant impact on treatment response. Journal of Acquired Immune Deficiency Syndromes, 37 (5), 1664-1666. doi:10.1097/00126334-200412150-00022

tasken, K., MOUTSCHEN, M., Rahmouni, S., Aandahl, E. M., Aukurst, P., Froland, S., Johansson, C., Hansson, V., & Klaveness, J. (29 April 2004). Use of COX-2 inhibitors for preventing immunodeficiency.

Elira Dokekias, A., Moutschen, M., Purhuence, M. F., Malanda, F., & Moyikoua, A. (2004). Myelome multiple et infection a VIH/SIDA : a propos de trois observations. Revue Médicale de Liège, 59 (2), 95-7.

Leonard, P., Moutschen, M., & Demonty, J. (June 2003). Prevention du paludisme chez l'adulte. Revue Médicale de Liège, 58 (6), 382-7.

GIOT, J.-B., Franchimont, N., & Moutschen, M. (March 2003). Anomalies du metabolisme osseux chez les patients infectes par le HIV et traites par tritherapie. Revue Médicale de Liège, 58 (3), 155-63.

Maquet, D., Croisier, J.-L., Moutschen, M., & Crielaard, J.-M. (March 2003). Isokinetic evaluation of muscular function in patients with chronic pain and fatigability. Isokinetics and Exercise Science, 11 (1), 73-74.

Blaise, P., Clevenbergh, P., Vaira, D., Moutschen, M., & Dellamonica, P. (2002). HIV resistance to antiretroviral drugs: Mechanisms, genotypic and phenotypic resistance testing in clinical practice. Acta Clinica Belgica, 57 (4, Jul-Aug), 191-201. doi:10.1179/acb.2002.041

Debruyn, X., Nkoghe, D., Leonard, P., Moutschen, M., & Demonty, J. (January 2002). Les anomalies morphologiques et metaboliques liees aux traitements antiretroviraux. Revue Médicale de Liège, 57 (1), 23-8.

Delbecque, K., Radermecker, M., Leonard, P., Moutschen, M., Hermans, G., Boniver, J., & de Leval, L. (2002). L'image du mois. Malacoplasie pulmonaire a Rhodococcus equi chez un patient atteint du SIDA. Revue Médicale de Liège, 57 (11), 685-7.

Derdelinckx, I., Van Laethem, K., Maes, B., Schrooten, Y., Dewit, S., Florence, E., Fransen, K., Ribas, S. G., Marissens, D., Moutschen, M., Van Wijngaerden, E., Vaira, D., Zissis, G., Van Ranst, M., & Vandamme, A.-M. (2002). Drug resistance among therapy-naive HIV-infected patients studied by sequencing and VERSANT (TM) HIV-1 resistance assays (LiPA) has limited impact on treatment response. Antiviral Therapy, 7 (Suppl. 1), 181.

Nkoghe, D., Demonty, J., Léonard, P., Nnegue, S., Moutschen, M., & Kaye, O. (2002). La maladie de Still de l'adulte. Revue Médicale de Liège, 57 (4), 213 - 219.

Baudoux, E., Blaffart, F., Bouffioux, C., Caprasse, M., Courtois, F., Cremasco, M.-R., De Pasqual, E., Fassotte, M.-F., Gillet, P., Lamy, M., Larbuisson, R., Lemaire, R., Merciny, M., Moutschen, M., Radermecker, M., Remy, B., & Sondag, D. (2000). La commission d'hemovigilance du CHU. Revue Médicale de Liège, 55 (9), 878-80.

Jacobs, N., Mazzoni, A., Mezzanzanica, D., Negri, D. R., Valota, O., Colnaghi, M. I., MOUTSCHEN, M., Boniver, J., & Canevari, S. (July 1997). Efficiency of T Cell Triggering by Anti-Cd3 Monoclonal Antibodies (Mab) with Potential Usefulness in Bispecific Mab Generation. Cancer Immunology, Immunotherapy, 44 (5), 257-64. doi:10.1007/s002620050381

Louis, E., Moutschen, M., de Marneffe, P., Malherbe, R., Closon, T., T'Jean, M., Demonty, J., & Belaiche, J. (1997). Extensive Ulcerative Colitis and Extraintestinal Manifestations in a Patient with Hiv Infection and Significant Cd4 T-Cell Lymphopenia. Gastroentérologie Clinique et Biologique, 21 (11), 884-7.

Jacobs, N., Greimers, R., Mazzoni, A., Trebak, M., Schaaf-Lafontaine, N., Boniver, J., & Moutschen, M. (July 1996). Further Characterization of Cytotoxic T Cells Generated by Short-Term Culture of Human Peripheral Blood Lymphocytes with Interleukin-2 and Anti-Cd3 Mab. Cancer Immunology, Immunotherapy, 42 (6), 369-75. doi:10.1007/s002620050296

Greimers, R., Trebak, M., Moutschen, M., Jacobs, N., & Boniver, J. (01 March 1996). Improved Four-Color Flow Cytometry Method Using Fluo-3 and Triple Immunofluorescence for Analysis of Intracellular Calcium Ion ([Ca2+]I) Fluxes among Mouse Lymph Node B- and T-Lymphocyte Subsets. Cytometry, 23 (3), 205-17. doi:10.1002/(SICI)1097-0320(19960301)23:3<205::AID-CYTO4>3.0.CO;2-H

Moutschen, M., Shan, H., Giantonio, B. J., & Bookman, M. A. (February 1994). Precursor CTL specific for retrovirus-induced T lymphoma are found at high frequency in unprimed syngeneic mice. Cellular Immunology, 153 (2), 367 - 377. doi:10.1006/cimm.1994.1035

Colombi, S., Deprez, M., de Leval, L., Humblet, C., Greimers, R., Defresne, M.-P., Boniver, J., & Moutschen, M. (1994). Thymus Involvement in Murine Acquired Immunodeficiency (Maids). Thymus, 23 (1), 27-37.

Moutschen, M., Colombi, S., Deprez, M., Van Wijk, F., Hotermans, C., Martin, M., Greimers, R., & Boniver, J. (1994). Population dynamics of CD4+ T cells lacking Thy-1 in murine retrovirus-induced immunodeficiency syndrome (MAIDS). Scandinavian Journal of Immunology, 39 (2), 216-24. doi:10.1111/j.1365-3083.1994.tb03363.x

Moutschen, M., Jacobs, N., Hoyoux, C., Martin-Simonet, M.-T., Schaaf-Lafontaine, N., & Boniver, J. (1994). Presence of gd TcR+ Tumor Infiltrating Lymphocytes (TILs) in One Case of Pediatric Osteogenic Sarcoma. International Journal of Pediatric Hematology/Oncology.

Jacobs, N., MOUTSCHEN, M., Boniver, J., Greimers, R., & Schaaf-Lafontaine, N. (February 1993). Efficient Immunoselection of Cytolytic Effectors with a Magnetic Cell Sorter. Research in Immunology, 144 (2), 141-50. doi:10.1016/0923-2494(93)80069-B

Boniver, J., Courtoy, R., Schaaf-Lafontaine, N., Martin-Simonet, M. T., Greimers, R., Rongy, A. M., Moutschen, M., Jacobs, N., Baudrihaye, M., Delvenne, P., Humblet, C., Lovens, D., Deman, J., Goffinet, G., & Defresne, M.-P. (1992). Cell Surface Receptors in Lymphoid Cells: From Cytochemistry to Molecular Biology and from a Phenotype to a Function. Progress in Histochemistry and Cytochemistry, 26 (1-4), 169-81. doi:10.1016/S0079-6336(11)80093-8