Publications and communications of Bernard Joris

Wan, H., Ben Othman, R., Le Corre, L., Poinsot, M., Oliver, M., Amoroso, A. M., Joris, B., Touzé, T., Auger, R., Calvet-Vitale, S., Bosco, M., & Gravier-Pelletier, C. (02 September 2022). New MraYAA Inhibitors with an Aminoribosyl Uridine Structure and an Oxadiazole. Antibiotics, 11 (9), 1189. doi:10.3390/antibiotics11091189

Oliver, M., Le Corre, L., Poinsot, M., Bosco, M., Wan, H., Amoroso, A. M., Joris, B., Bouhss, A., Calvet-Vitale, S., & Gravier-Pelletier, C. (08 March 2022). A Sub-Micromolar MraYAA Inhibitor with an Aminoribosyl Uridine Structure and a (S,S)-Tartaric Diamide: Synthesis, Biological Evaluation and Molecular Modeling. Molecules, 27 (6), 1769. doi:10.3390/molecules27061769

Lupo, V., Mercuri, P., Frère, J.-M., Joris, B., Galleni, M., Baurain, D.* , & Kerff, F.*. (2022). An Extended Reservoir of Class-D Beta-Lactamases in Non-Clinical Bacterial Strains. Microbiology Spectrum, 10 (2), 0031522. doi:10.1128/spectrum.00315-22

Oliver, M., Le Corre, L., Poinsot, M., Corio, A., Madegard, L., Bosco, M., Amoroso, A. M., Joris, B., Auger, R., Touzé, T., Bouhss, A., Calvet-Vitale, S., & Gravier-Pelletier, C. (2021). Synthesis, biological evaluation and molecular modeling of urea-containing MraY inhibitors. Organic and Biomolecular Chemistry, 19 (26), 5844-5866. doi:10.1039/d1ob00710f

Decuyper, L., Jukič, M., Sosič, I., Amoroso, A. M., Verlaine, O., Joris, B., Gobec, S., & D'hooghe, M. (02 January 2020). Synthesis and Penicillin-binding Protein Inhibitory Assessment of Dipeptidic 4-Phenyl-β-lactams from α-Amino Acid-derived Imines. Chemistry: An Asian Journal, 15 (1), 51-55. doi:10.1002/asia.201901470

Decuyper, L., Magdalenić, K., Verstraete, M.-B., Jukič, M., Sosič, I., Sauvage, E., Amoroso, A. M., Verlaine, O., Joris, B., Gobec, S., & D'hooghe, M. (09 October 2019). α-Unsaturated 3-Amino-1-carboxymethyl-β-lactams as Bacterial PBP Inhibitors: Synthesis and Biochemical Assessment. Chemistry, 25 (70), 16128 - 16140. doi:10.1002/chem.201904139

Decuyper, L., Deketelaere, S., Vanparys, L., Jukič, M., Sosič, I., Sauvage, E., Amoroso, A. M., Verlaine, O., Joris, B., Gobec, S., & D'hooghe, M. (12 October 2018). In Silico Design and Enantioselective Synthesis of Functionalized Monocyclic 3-Amino-1-carboxymethyl-β-lactams as Inhibitors of Penicillin-Binding Proteins of Resistant Bacteria. Chemistry, 24 (57), 15254-15266. doi:10.1002/chem.201801868

Lara, Y., Durieu, B., Cornet, L., Verlaine, O., Rippka, R., Stelmach Pessi, I., Misztak, A., Joris, B., Javaux, E., Baurain, D., & Wilmotte, A. (2017). Draft genome sequence of the axenic strain Phormidesmis priestleyi ULC007, a cyanobacterium isolated from Lake Bruehwiler (Larsemann Hills, Antarctica). Genome Announcements, 01546-16. doi:10.1128/genomeA.01546-16

Di Gregorio, S., Fernandez, S., Cuirolo, A., Verlaine, O., Amoroso, A. M., Mengin-Lecreulx, D., Famiglietti, A., Joris, B., & Mollerach, M. (January 2017). Different Vancomycin-Intermediate Staphylococcus aureus Phenotypes Selected from the Same ST100-hVISA Parental Strain. Microbial Drug Resistance: Mechanism, Epidemiology, and Disease, 23 (1), 44-50. doi:10.1089/mdr.2016.0160

Maréchal, M., Amoroso, A. M., Morlot, C., Vernet, T., Coyette, J., & Joris, B. (12 October 2016). Enterococcus hirae LcpA (Psr), a new peptidoglycan-binding protein localized at the division site. BMC Microbiology, 16 (1), 239. doi:10.1186/s12866-016-0844-y

Vanden Broeck, A., Van Der Heiden, E., Sauvage, E., Dauvin, M., Joris, B., & Duez, C. (2015). A lysine cluster in domain II of Bacillus subtilis PBP4a plays a role in the membrane attachment of this C1-PBP. PLoS ONE. doi:10.1371/journal.pone.0140082

Lamborelle, N., Monbaliu, J.-C., Simon, J., Joris, B., & Luxen, A. (June 2015). Enantioselective Synthesis of Vinyglycine Derivatives Using Continuous-Flow Thermolysis for Meso- Diaminopimelic Acid Preparation [Poster presentation]. Biomedica 2015, Genk, Belgium.

Fer, M., Bouhss,, A. B., Patrão, M., Le Corre, L., Pietrancosta, N., Amoroso, A. M., Joris, B., Mengin-Lecreulx, D., Calvet-Vitale, S., & Gravier-Pelletier, C. (May 2015). 5′-Methylene-triazole-substituted-aminoribosyl uridines as MraY inhibitors: synthesis, biological evaluation and molecular modeling. Organic and Biomolecular Chemistry, 13 (26), 7193. doi:10.1039/c5ob00707k

Calusinska, M., Hamilton, C., Monsieurs, P., Mathy, G., Leys, N., Franck, F., Joris, B., Thonart, P., Hiligsmann, S., & Wilmotte, A. (2015). Genome-wide transcriptional analysis suggests hydrogenase- and nitrogenase-mediated hydrogen production in Clostridium butyricum CWBI 1009. Biotechnology for Biofuels, 8 (27), 1-16. doi:10.1186/s13068-015-0203-5

Crowet, J.-M., Dony, N., Joris, B., Brasseur, R., & Lins, L. (28 November 2014). Structure predictions of membrane domains of proteins from the Divisome and BlaR [Poster presentation]. IAP 7/44 Meeting: Integrative Protein Science: from small molecules to complex biological systems - iPros Date(s) de la manifestation.

Brans, A., Joris, B., Delmarcelle, M., Marchand, J., Tulkens, P., Hammaecher, C., Goormaghtigh, E., & De Conink, J. (28 August 2014). METHOD FOR MEASURING BETA-LACTAM ANTIBIOTICS.

Lamborelle, N., Simon, J., Lemaire, C., Joris, B., & Luxen, A. (June 2014). Stereoselective synthesis of stable isotopomers of meso -2,6-diaminopimelic acid [Poster presentation]. 15th Tetrahedron Symposium Challenges in Bioorganic and Organic Medicinal Chemistry, Londres, United Kingdom.

Franck, F., Remacle, C., Wilmotte, A., Joris, B., Thonart, P., & Hiligsmann, S. (2014). Summary of ARC Final Report – MicroH2 - A collaborative project on algal and bacterial H2 production. ULg - Université de Liège.

Henry, X., Verlaine, O., Amoroso, A. M., Coyette, J., & Joris, B. (December 2013). Activity of ceftaroline against Enterococcus faecium PBP5. Antimicrobial Agents and Chemotherapy, 57 (12), 6358. doi:10.1128/AAC.00923-13

Dony, N., Crowet, J.-M., Joris, B., Brasseur, R., & Lins, L. (May 2013). SAHBNET, an Accessible Surface-Based Elastic Network: An Application to Membrane Protein. International Journal of Molecular Sciences, 14 (6), 11510-26. doi:10.3390/ijms140611510

Arguelles Arias, A., Ongena, M., Devreese, B., Terrak, M., Joris, B., & Fickers, P. (2013). Characterization of amylolysin, a novel lantibiotic from Bacillus amyloliquefaciens GA1. PLoS ONE, 8 (12). doi:10.1371/journal.pone.0083037

Amoroso, A. M., Boudet, J., Berzigotti, S., Duval, V., Teller, N., Mengin-Lecreulx, D., Luxen, A., Simorre, J.-P., & Joris, B. (2012). A peptidoglycan fragment triggers beta-lactam resistance in Bacillus licheniformis. PLoS Pathogens, 8 (3), 1002571. doi:10.1371/journal.ppat.1002571

Berzigotti, S., Benlafya, K., Sepulchre, J., Amoroso, A. M., & Joris, B. (2012). Bacillus licheniformis BlaR1 L3 loop is a Zinc metalloprotease activated by self-proteolysis. PLoS ONE, 7, 36400. doi:10.1371/journal.pone.0036400

Dumbre, S., Derouaux, A., Lescrinier, E., Piette, A., Joris, B., Terrak, M., & Herdewijn, P. (2012). Synthesis of Modified Peptidoglycan Precursor Analogues for the Inhibition of Glycosyltransferase. Journal of the American Chemical Society. doi:10.1021/ja302099u

Joris, B., & Dusart, J. (2012). The induction of beta-lactamases in Eubacteria. In J.-M. Frère & V. N. Uversky (Eds.), Beta-lactamases. Hauppauge, NY, United States: Nova Science Publishers.

Masset, J., Calusinska, M., Hamilton, C., Hiligsmann, S., Joris, B., Wilmotte, A., & Thonart, P. (2012). Fermentative hydrogen production from glucose and starch using pure strains and artificial co-cultures ofClostridium spp. Biotechnology for Biofuels, 5 (35), 1-15.

Zervosen, A., Bouillez, A., Herman, A., Amoroso, A. M., Joris, B., Sauvage, E., Charlier, P., & Luxen, A. (2012). Synthesis and evaluation of boronic acids as inhibitors of Penicillin Binding Proteins of classes A, B and C. Bioorganic and Medicinal Chemistry, 20 (12), 3915-24. doi:10.1016/j.bmc.2012.04.018

Zervosen, A., Herman, R., Kerff, F., Herman, A., Bouillez, A., Prati, F., Pratt, R. F., Frère, J.-M., Joris, B., Luxen, A., Charlier, P., & Sauvage, E. (2011). Unexpected tricovalent binding mode of boronic acids within the active site of a penicillin binding protein. Journal of the American Chemical Society. doi:10.1021/ja200696y

Sosic, I., Barreteau, H., Simcic, M., Sink, R., Cesar, J., Zega, A., Grdadolnik, S. G., Contreras-Martel, C., Dessen, A., Amoroso, A. M., Joris, B., Blanot, D., & Gobec, S. (2011). Second-generation sulfonamide inhibitors of D-glutamic acid-adding enzyme: activity optimisation with conformationally rigid analogues of D-glutamic acid. European Journal of Medicinal Chemistry, 46 (7), 2880-94. doi:10.1016/j.ejmech.2011.04.011

Turk, S., Verlaine, O., Gerards, T., Zivec, M., Humljan, J., Sosic, I., Amoroso, A. M., Zervosen, A., Luxen, A., Joris, B., & Gobec, S. (2011). New noncovalent inhibitors of penicillin-binding proteins from penicillin-resistant bacteria. PLoS ONE, 6 (5), 19418. doi:10.1371/journal.pone.0019418

Halimi, B. E., Dortu, C., Arguelles Arias, A., Thonart, P., Joris, B., & Fickers, P. (2010). Antilisterial Activity on Poultry Meat of Amylolysin, a Bacteriocin from Bacillus amyloliquefaciens GA1. Probiotics and Antimicrobial Proteins. doi:10.1007/s12602-010-9040-9

Calusinska, M., Happe, T., Joris, B., & Wilmotte, A. (2010). The surprising diversity of clostridial hydrogenases: a comparative genomic perspective. Microbiology, 156, 1575-1588. doi:10.1099/mic.0.032771-0

Kern, T., Giffard, M., Hediger, S., Amoroso, A. M., Giustini, C., Khai Bui, N., Joris, B., Vollmer, & Simorre, J.-P. (2010). Dynamics Characterization of Fully Hydrated Bacterial Cell Walls by Solid-State NMR: Evidence for Cooperative Binding of Metal Ions. Journal of the American Chemical Society, 132, 10911-10919. doi:10.1021/ja104533w

Arguelles Arias, A., Ongena, M., Halimi, B., Lara, Y., Brans, A., Joris, B., & Fickers, P. (26 November 2009). Bacillus amyloliquefaciens GA1 as a source of potent antibiotics and other secondary metabolites for biocontrol of plant pathogens. Microbial Cell Factories, 8 (1), 63. doi:10.1186/1475-2859-8-63

Sauvage, E., Zervosen, A., Dive, G., Herman, R., Amoroso, A. M., Joris, B., Fonzé, E., Pratt, R., Luxen, A., Charlier, P., & Kerff, F. (2009). Structural basis of the inhibition of class A beta-lactamases and penicillin-binding proteins by 6-beta-iodopenicillanate. Journal of the American Chemical Society, 131 (42), 15262-15269. doi:10.1021/ja9051526

Colson, S., van Wezel, G. P., Craig, M., Noens, E. E., Nothaft, H., Mommaas, A. M., Titgemeyer, F., Joris, B., & Rigali, S. (February 2008). The Chitobiose-Binding Protein, DasA, Acts as a Link between Chitin Utilization and Morphogenesis in Streptomyces Coelicolor. Microbiology, 154 (Pt 2), 373-82. doi:10.1099/mic.0.2007/011940-0

Hiard, S., Marée, R., Colson, S., Hoskisson, P. A., Titgemeyer, F., van Wezel, G. P., Joris, B., Wehenkel, L., & Rigali, S. (June 2007). PREDetector: A new tool to identify regulatory elements in bacterial genomes. Biochemical and Biophysical Research Communications, 357 (4), 861-864. doi:10.1016/j.bbrc.2007.03.180

Rigali, S., Nothaft, H., Noens, E. E. E., Schlicht, M., Colson, S., Müller, M., Joris, B., Koerten, H. K., Hopwood, D. A., Titgemeyer, F., & van Wezel, G. P. (September 2006). The sugar phosphotransferase system of Streptomyces coelicolor is regulated by the GntR-family regulator DasR and links N-acetylglucosamine metabolism to the control of development. Molecular Microbiology, 61 (5), 1237-1251. doi:10.1111/j.1365-2958.2006.05319.x

Brans, A., Filée, P., Chevigné, A., Claessens, A., & Joris, B. (December 2004). New integrative method to generate Bacillus subtilis recombinant strains free of selection markers. Applied and Environmental Microbiology, 70 (12), 7241-7250. doi:10.1128/AEM.70.12.7241-7250.2004

Rigali, S., Schlicht, M., Hoskisson, P., Nothaft, H., Merzbacher, M., Joris, B., & Titgemeyer, F. (June 2004). Extending the classification of bacterial transcription factors beyond the helix-turn-helix motif as an alternative approach to discover new cis/trans relationships. Nucleic Acids Research, 32 (11), 3418-3426. doi:10.1093/nar/gkh673

Genereux, C., Dehareng, D., Devreese, B., Van Beeumen, J., Frère, J.-M., & Joris, B. (01 January 2004). Mutational analysis of the catalytic centre of the Citrobacter freundii AmpD N-acetylmuramyl-L-alanine amidase. Biochemical Journal, 377 (Pt 1), 111-120. doi:10.1042/BJ20030862

Duval, V., Swinnen, M., Lepage, S., Brans, A., Granier, B., Franssen, C., Frère, J.-M., & Joris, B. (June 2003). The kinetic properties of the carboxy terminal domain of the Bacillus licheniformis 749/I BlaR penicillin-receptor shed a new light on the derepression of beta-lactamase synthesis. Molecular Microbiology, 48 (6), 1553-1564. doi:10.1046/j.1365-2958.2003.03520.x

Liepinsh, E., Genereux, C., Dehareng, D., Joris, B., & Otting, G. (2003). NMR structure of Citrobacter freundii AmpD, comparison with bacteriophage T7 lysozyme and homology with PGRP domains. Journal of Molecular Biology, 327 (4), 833-42. doi:10.1016/S0022-2836(03)00185-2

Melckebeke, H. V., Vreuls, C., Gans, P., Filée, P., Llabres, G., Joris, B., & Simorre, J.-P. (2003). Solution structural study of BlaI: implications for the repression of genes involved in beta-lactam antibiotic resistance. Journal of Molecular Biology, 333 (4), 711-20. doi:10.1016/j.jmb.2003.09.005

Filée, P., Benlafya, K., Delmarcelle, M., Moutzourelis, G., Frère, J.-M., Brans, A., & Joris, B. (May 2002). The fate of the Blal repressor during the induction of the Bacillus licheniformis BlaP beta-lactamase. Molecular Microbiology, 44 (3), 685-694. doi:10.1046/j.1365-2958.2002.02888.x

Dinant, M.* , Baurain, D.* , Coosemans, N., Joris, B., & Matagne, R.-F. (April 2001). Characterization of two genes encoding the mitochondrial alternative oxidase in Chlamydomonas reinhardtii. Current Genetics, 39 (2), 101-108. doi:10.1007/s002940000183

Cheggour, A., Fanuel, L., Duez, C., Joris, B., Bouillenne, F., Devreese, B., Van Driessche, G., Van Beeumen, J., Frère, J.-M., & Goffin, C. (November 2000). The Dppa Gene of Bacillus Subtilis Encodes a New D-Aminopeptidase. Molecular Microbiology, 38 (3), 504-13. doi:10.1046/j.1365-2958.2000.02117.x

Bompard-Gilles, C., Villeret, V., Davies, G. J., Fanuel, L., Joris, B., Frère, J.-M., & Van Beeumen, J. (2000). A new variant of the Ntn hydrolase fold revealed by the crystal structure of L-aminopeptidase D-ala-esterase/amidase from Ochrobactrum anthropi. Structure, 8 (2), 153-62. doi:10.1016/S0969-2126(00)00091-5

Bompard-Gilles, C., Villeret, V., Fanuel, L., Joris, B., Frère, J.-M., & Van Beeumen, J. (1999). Crystallization and preliminary X-ray analysis of a new L-aminopeptidase-D-amidase/D-esterase activated by a Gly-Ser peptide bond hydrolysis. Acta Crystallographica. Section D, Biological Crystallography, 55 (Pt 3), 699-701. doi:10.1107/S0907444998015807

Fanuel, L., Goffin, C., Cheggour, A., Devreese, B., Van Driessche, G., Joris, B., Van Beeumen, J., & Frère, J.-M. (1999). The DmpA aminopeptidase from Ochrobactrum anthropi LMG7991 is the prototype of a new terminal nucleophile hydrolase family. Biochemical Journal, 341 (Pt 1), 147-55. doi:10.1042/0264-6021:3410147

Fanuel, L., Thamm, I., Kostanjevecki, V., Samyn, B., Joris, B., Goffin, C., Brannigan, J., Van Beeumen, J., & Frère, J.-M. (1999). Two new aminopeptidases from Ochrobactrum anthropi active on D-alanyl-p-nitroanilide. Cellular and Molecular Life Sciences, 55 (5), 812-8. doi:10.1007/s000180050334

Philippon, A., Dusart, J., Joris, B., & Frère, J.-M. (1998). The diversity, structure and regulation of beta-lactamases. Cellular and Molecular Life Sciences, 54 (4), 341-6. doi:10.1007/s000180050161

Lepage, S., Dubois, P., Ghosh, T.-K., Joris, B., Mahapatra, S., Kundu, M., Basu, J., Chakrabarti, P., Cole, S.-T., Nguyen-Distèche, M., & Ghuysen, J.-M. (July 1997). Dual Multimodular Class a Penicillin-Binding Proteins in Mycobacterium Leprae. Journal of Bacteriology, 179 (14), 4627-4630. doi:10.1128/jb.179.14.4627-4630.1997

Guillaume, G., Vanhove, M., Lamotte-Brasseur, J., Ledent, P., Jamin, M., Joris, B., & Frère, J.-M. (1997). Site-directed mutagenesis of glutamate 166 in two beta-lactamases. Kinetic and molecular modeling studies. Journal of Biological Chemistry, 272 (9), 5438-44. doi:10.1074/jbc.272.9.5438

Hardt, K., Joris, B., Lepage, S., Brasseur, R., Lampen, J. O., Frère, J.-M., Fink, A. L., & Ghuysen, J.-M. (1997). The Penicillin sensory transducer, blar, involved in the inducibility of beta-lactamase synthesis in bacillus licheniformis is embedded in the plasma membrane via a four-alpha-helix bundle. Molecular Microbiology, 23 (5), 935-944. doi:10.1046/j.1365-2958.1997.2761642.x

Kunst, F., Ogasawara, N., Moszer, I., Albertini, A., Alloni, G., Azevedo, V., Bertero, M., Bessieres, P., Bolotin, A., Borchert, S., Borriss, R., Rapoport, G., Rey, M., Reynolds, S., Rieger, M., Rivolta, C., Rocha, E., Roche, B., Rose, M., ... Purnelle, B. (1997). The Complete Genome Sequence Of The Gram-Positive Bacterium Bacillus Subtilis. Nature, 390 (6657), 249-256. doi:10.1038/36786

Magdalena, J., Gérard, C., Joris, B., Forsman, M., & Dusart, J. (1997). The two beta-lactamase genes of Streptomyces cacaoi, blaL and blaU, are under the control of the same regulatory system. Molecular and General Genetics, 255 (2), 187-93. doi:10.1007/s004380050488

Basu, J., Mahapatra, S., Kundu, M., Mukhopadhyay, S., Nguyen-Distèche, M., Dubois, P., Joris, B., Van Beeumen, J., Cole, S.-T., Chakrabarti, P., & Ghuysen, J.-M. (March 1996). Identification and overexpression in Escherichia coli of a Mycobacterium leprae gene, pon1, encoding a high-molecular-mass class A penicillin-binding protein, PBP1. Journal of Bacteriology, 178 (6), 1707-1711. doi:10.1128/jb.178.6.1707-1711.1996

Ghuysen, J.-M., Charlier, P., Coyette, J., Duez, C., Fonze, E., Fraipont, C., Joris, B., Nguyen-Distèche, M., & Goffin, C. (1996). Penicillin and Beyond: Evolution, Protein Fold, Multimodular Polypeptides, and Multiprotein Complexes. Microbial Drug Resistance: Mechanism, Epidemiology, and Disease, 2 (2, Summer), 163-175. doi:10.1089/mdr.1996.2.163

Hendrix, C., Anne, J., Joris, B., Van Aerschot, A., & Herdewijn, P. (1996). Selection of hammerhead ribozymes for optimum cleavage of interleukin 6 mRNA. Biochemical Journal, 314 ( Pt 2), 655-61. doi:10.1042/bj3140655

Lammertyn, E., Van Mellaert, L., Bijnens, A. P., Joris, B., & Anne, J. (1996). Codon adjustment to maximise heterologous gene expression in Streptomyces lividans can lead to decreased mRNA stability and protein yield. Molecular and General Genetics, 250 (2), 223-9. doi:10.1007/s004380050070

Anne, J., Fiten, P., Van Mellaert, L., Joris, B., Opdenakker, G., & Eyssen, H. (1995). Analysis of the open reading frames of the main capsid proteins of actinophage VWB. Archives of Virology, 140 (6), 1033-47. doi:10.1007/BF01315413

Duez, C., Piron-Fraipont, C., Joris, B., Dusart, J., Urdea, M.-S., Martial, J., Frère, J.-M., & Ghuysen, J.-M. (15 September 1994). Erratum for : primary structure of the streptomyces R61 extracellular DD-peptidase. 1. Cloning into Streptomyces lividans and nucleotide sequence of the gene. European Journal of Biochemistry, 224 (3), 1079. doi:10.1111/j.1432-1033.1994.01079.x

Fanuel, L., Granier, B., Wilkin, J.-M., Bellefroid-Bourguignon, C., Joris, B., Knowles, J., Komives, E., Van Beeumen, J., Ghuysen, J.-M., & Frère, J.-M. (29 August 1994). The Precursor of the Streptomyces R61 Dd-Peptidase Containing a C-Terminal Extension Is Inactive. FEBS Letters, 351 (1), 49-52. doi:10.1016/0014-5793(94)00822-1

Ghuysen, J.-M., Lamotte-Brasseur, J., Joris, B., & Shockman, G. D. (28 March 1994). Binding Site-Shaped Repeated Sequences of Bacterial Wall Peptidoglycan Hydrolases. FEBS Letters, 342 (1), 23-28. doi:10.1016/0014-5793(94)80577-6

Datz, M., Joris, B., Azab, E. A., Galleni, M., Van Beeumen, J., Frère, J.-M., & Martin, H. H. (1994). A common system controls the induction of very different genes. The class-A beta-lactamase of Proteus vulgaris and the enterobacterial class-C beta-lactamase. European Journal of Biochemistry, 226 (1), 149-57. doi:10.1111/j.1432-1033.1994.tb20036.x

Granier, B., Jamin, M., Adam, M., Galleni, M., Lakaye, B., Zorzi, W., Grandchamps, J., Wilkin, J.-M., Fraipont, C., Joris, B., Duez, C., Nguyen-Distèche, M., Coyette, J., Leyh-Bouille, M., Dusart, J., Christians, L., Frère, J.-M., & Ghuysen, J.-M. (1994). Serine-Type D-Ala-D-Ala Peptidases and Penicillin-Binding Proteins. Methods in Enzymology, 244, 249-266. doi:10.1016/0076-6879(94)44021-2

Joris, B., Galleni, M., Frère, J.-M., & Labia, R. (1994). Analysis of the penA gene of Pseudomonas cepacia 249. Antimicrobial Agents and Chemotherapy, 38 (2), 407-8. doi:10.1128/AAC.38.2.407

Timm, J., Perilli, M. G., Duez, C., Trias, J., Orefici, G., Fattorini, L., Amicosante, G., Oratore, A., Joris, B., & Frère, J.-M. (1994). Transcription and expression analysis, using lacZ and phoA gene fusions, of Mycobacterium fortuitum beta-lactamase genes cloned from a natural isolate and a high-level beta-lactamase producer. Molecular Microbiology, 12 (3), 491-504. doi:10.1111/j.1365-2958.1994.tb01037.x

Wilkin, J. M., Dubus, A., Joris, B., & Frère, J.-M. (1994). The mechanism of action of DD-peptidases: the role of Threonine-299 and -301 in the Streptomyces R61 DD-peptidase. Biochemical Journal, 301 ( Pt 2), 477-83. doi:10.1042/bj3010477

Englebert, S., El Kharroubi, A., Piras, G., Joris, B., Coyette, J., Nguyen-Distèche, M., & Ghuysen, J.-M. (1993). Modular Design of the Bi(multi?) functional penicillin-binding proteins. In De pedro, J. V. Höltje, ... W. Loffelhardt (Eds.), Bacterial Growth & Lysis Metabolism and Structure of the Bacterial Sacculus (pp. 319-333). New York, United States: Plenum Press.

Hourdou, M.-L., Guinand, M., Vacheron, M.-J., Denoroy, L., Duez, C., Englebert, S., Joris, B., Weber, G., Ghuysen, J.-M., & Michel, G. (01 June 1993). Characterization of the Sporulation-Related Gamma-D-Glutamyl-(L)Meso-Diaminopimelic-Acid-Hydrolysing Peptidase I of Bacillus Sphaericus NCTC 9602 as a Member of the Metallo(Zinc) Carboxypeptidase A Family. Modular Design of the Protein. Biochemical Journal, 292 (Pt 2), 563-570. doi:10.1042/bj2920563

Wilkin, J.-M., Jamin, M., Damblon, C., Zhao, G.-H., Joris, B., Duez, C., & Frère, J.-M. (15 April 1993). The Mechanism of Action of DD-Peptidases: The Role of Tyrosine-159 in the Streptomyces R61 DD-Peptidase. Biochemical Journal, 291 (Part 2), 537-544. doi:10.1042/bj2910537

Felici, A., Amicosante, G., Oratore, A., Strom, R., Ledent, P., Joris, B., Fanuel, L., & Frère, J.-M. (1993). An overview of the kinetic parameters of class B beta-lactamases. Biochemical Journal, 291 ( Pt 1), 151-5. doi:10.1042/bj2910151

Ledent, P., Raquet, X., Joris, B., Van Beeumen, J., & Frère, J.-M. (1993). A comparative study of class-D beta-lactamases. Biochemical Journal, 292 ( Pt 2), 555-62. doi:10.1042/bj2920555

Malissard, M., Duez, C., Guinand, M., Vacheron, M.-J., Michel, G., Marty, N., Joris, B., Thamm, I., & Ghuysen, J.-M. (1993). Sequence of a gene encoding a (poly ManA) alginate lyase active on Pseudomonas aeruginosa alginate. FEMS Microbiology Letters, 110 (1), 101-106. doi:10.1111/j.1574-6968.1993.tb06302.x

Wilkin, J. M., Jamin, M., Joris, B., & Frère, J.-M. (1993). Mechanism of action of DD-peptidases: role of asparagine-161 in the Streptomyces R61 DD-peptidase. Biochemical Journal, 293 ( Pt 1), 195-201. doi:10.1042/bj2930195

Lenzini, V. M., Magdalena, J., Fraipont, C., Joris, B., Matagne, A., & Dusart, J. (October 1992). Induction of a Streptomyces Cacaoi Beta-Lactamase Gene Cloned in S. Lividans. Molecular and General Genetics, 235 (1), 41-8. doi:10.1007/BF00286179

Zhu, Y., Englebert, S., Joris, B., Ghuysen, J.-M., Kobayashi, T., & Lampen, J.-O. (01 October 1992). Structure, function, and fate of the BlaR signal transducer involved in induction of β-lactamase in Bacillus licheniformis. Journal of Bacteriology, 174 (19), 6171-6178. doi:10.1128/jb.174.19.6171-6178.1992

Hadonou, A. M., Wilkin, J.-M., Varetto, L., Joris, B., Lamotte-Brasseur, J., Klein, D., Duez, C., Ghuysen, J.-M., & Frère, J.-M. (01 July 1992). Site-Directed Mutagenesis of the Streptomyces R61 Dd-Peptidase. Catalytic Function of the Conserved Residues around the Active Site and a Comparison with Class-a and Class-C Beta-Lactamases. European Journal of Biochemistry, 207 (1), 97-102. doi:10.1111/j.1432-1033.1992.tb17025.x

Bourguignon-Bellefroid, C., Joris, B., Van Beeumen, J., Ghuysen, J.-M., & Frère, J.-M. (01 April 1992). Point Mutations of Two Arginine Residues in the Streptomyces R61 Dd-Peptidase. Biochemical Journal, 283 (1), 123-128. doi:10.1042/bj2830123

Joris, B., Englebert, S., Chu, C.-P., Kariyama, R., Daneo-Moore, L., Shockman, G. D., & Ghuysen, J.-M. (15 March 1992). Modular Design of the Enterococcus Hirae Muramidase-2 and Streptococcus Faecalis Autolysin. FEMS Microbiology Letters, 91 (3), 257-264. doi:10.1016/0378-1097(92)90707-U

Bourguignon-Bellefroid, C., Wilkin, J.-M., Joris, B., Aplin, R. T., Houssier, C., Prendergast, F. G., Van Beeumen, J., Ghuysen, J.-M., & Frère, J.-M. (01 March 1992). Importance of the Two Tryptophan Residues in the Streptomyces R61 Exocellular Dd-Peptidase. Biochemical Journal, 282 (Pt 2), 361-367. doi:10.1042/bj2820361

Hadonou, A. M., Jamin, M., Adam, M., Joris, B., Dusart, J., Ghuysen, J.-M., & Frère, J.-M. (01 March 1992). Importance of the His-298 Residue in the Catalytic Mechanism of the Streptomyces R61 Extracellular Dd-Peptidase. Biochemical Journal, 282 (Pt 2), 495-500. doi:10.1042/bj2820495

Hourdou, M.-L., Duez, C., Joris, B., Vacheron, M.-J., Guinand, M., Michel, G., & Ghuysen, J.-M. (01 March 1992). Cloning and nucleotide sequence of the gene encoding the γ-D-glutamyl-L-diamino acid endopeptidase II of Bacillus sphaericus. FEMS Microbiology Letters, 91 (2), 165-170. doi:10.1016/0378-1097(92)90678-H

Matagne, A., Joris, B., & Frère, J.-M. (01 December 1991). Anomalous Behaviour of a Protein During Sds/Page Corrected by Chemical Modification of Carboxylic Groups. Biochemical Journal, 280 ((Pt 2)), 553-6. doi:10.1042/bj2800553

Joris, B., Ledent, P., Dideberg, O., Fonze, E., Lamotte-Brasseur, J., Kelly, J. A., Ghuysen, J.-M., & Frère, J.-M. (November 1991). Comparison of the Sequences of Class a β-lactamase and of the Secondary Structure Elements of Penicillin-Recognizing Proteins. Antimicrobial Agents and Chemotherapy, 35 (11), 2294-2301. doi:10.1128/AAC.35.11.2294

Jacob, F., Joris, B., & Frère, J.-M. (01 August 1991). Active-Site Serine Mutants of the Streptomyces Albus G Beta-Lactamase. Biochemical Journal, 277 ((Pt 3)), 647-52. doi:10.1042/bj2770647

Ambler, R. P., Coulson, A. F. W., Frère, J.-M., Ghuysen, J.-M., Joris, B., Forsman, M., Levesque, R. C., Tiraby, G., & Waley, S. G. (15 May 1991). A standard numbering scheme for the class A beta-lactamases. Biochemical Journal, 276 (Pt 1), 269-270. doi:10.1042/bj2760269

Matagne, A., Joris, B., Van Beeumen, J., & Frère, J.-M. (01 February 1991). Ragged N-Termini and Other Variants of Class a Beta-Lactamases Analysed by Chromatofocusing. Biochemical Journal, 273 (273), 503-10. doi:10.1042/bj2730503

BRANNIGAN, J., Matagne, A., Jacob, F., Damblon, C., Joris, B., KLEIN, D., SPRATT, B. G., & Frère, J.-M. (1991). THE MUTATION LYS234HIS YIELDS A CLASS-A BETA-LACTAMASE WITH A NOVEL PH-DEPENDENCE. Biochemical Journal, 278 (Part 3), 673-678. doi:10.1042/bj2780673

Loppes, R., Michels, R., Decroupette, I., & Joris, B. (1991). Sequence analysis of the ARG7 gene of Schizosaccharomyces pombe coding for argininosuccinate lyase. Expression of the gene in Saccharomyces cerevisiae. Current Genetics, 19 (4), 255-60. doi:10.1007/BF00355051

Jacob, F., Joris, B., Lepage, S., Dusart, J., & Frère, J.-M. (15 October 1990). Role of the Conserved Amino Acids of the 'Sdn' Loop (Ser130, Asp131 and Asn132) in a Class a Beta-Lactamase Studied by Site-Directed Mutagenesis. Biochemical Journal, 271 (2), 399-406. doi:10.1042/bj2710399

Jacob, F., Joris, B., Dideberg, O., Dusart, J., Ghuysen, J.-M., & Frère, J.-M. (October 1990). Engineering a Novel β-Lactamase by a Single Point Mutation. Protein Engineering, 4 (1), 79-86. doi:10.1093/protein/4.1.79

Joris, B., Ledent, P., Kobayashi, T., Lampen, J.-O., & Ghuysen, J.-M. (15 June 1990). Expression in Escherichia Coli of the Carboxy Terminal Domain of the Blar Sensory-Transducer Protein of Bacillus Licheniformis as a Water-Soluble Mr 26,000 Penicillin-Binding Protein. FEMS Microbiology Letters, 58 (1), 107-113. doi:10.1016/0378-1097(90)90111-3

Joris, B., Dive, G., Henriques, A., Piggot, P. J., & Ghuysen, J.-M. (March 1990). The Life-Cycle Proteins Roda of Escherichia Coli and Spove of Bacillus Subtilis Have Very Similar Primary Structures. Molecular Microbiology, 4 (3), 513-517. doi:10.1111/j.1365-2958.1990.tb00618.x

Zhu, Y.-F., Curran, I. H. A., Joris, B., Ghuysen, J.-M., & Lampen, J. O. (01 February 1990). Identification of BlaR, the signal transducer for β-lactamase production in Bacillus licheniformis, as a penicillin-binding protein with strong homology to the OXA-2 β-lactamase (class D) of Salmonella typhimurium. Journal of Bacteriology, 172 (2), 1137-1141. doi:10.1128/jb.172.2.1137-1141.1990

Matagne, A., Misselyn-Bauduin, A. M., Joris, B., Erpicum, T., Granier, B., & Frère, J.-M. (01 January 1990). The Diversity of the Catalytic Properties of Class a Beta-Lactamases. Biochemical Journal, 265 (1), 131-46. doi:10.1042/bj2650131

Laible, G., Hakenbeck, R., Sicard, M. A., Joris, B., & Ghuysen, J.-M. (01 October 1989). Nucleotide sequences of the pbpX genes encoding the penicillin-binding proteins 2x from Streptococcus pneumoniae R6 and a cefotaxime-resistant mutant, C506. Molecular Microbiology, 3 (10), 1337-1348. doi:10.1111/j.1365-2958.1989.tb00115.x

Leyh-Bouille, M., Vanbeeumen, J., Renier-Pirlot, S., Joris, B., Nguyen-Distèche, M., & Ghuysen, J.-M. (1989). The Streptomyces K15 DD-peptidase/penicillin-binding protein. Active site and sequence of the N-terminal region. Biochemical Journal, 260 (2), 601-604. doi:10.1042/bj2600601

Joris, B., Ghuysen, J.-M., Dive, G., Renard, A., Dideberg, O., Charlier, P., Frère, J.-M., Kelly, J. A., Boyington, J., Moews, P. C., & Knox, J. (01 March 1988). The Active-Site-Serine Penicillin-Recognizing Enzymes as Members of the Streptomyces R61 Dd-Peptidase Family. Biochemical Journal, 250 (2), 313-324. doi:10.1042/bj2500313

Amicosante, G., Oratore, A., Joris, B., Galleni, M., Frère, J.-M., & Van Beeumen, J. (1988). Chromosome-encoded beta-lactamases of Citrobacter diversus. Interaction with beta-iodopenicillanate and labelling of the active site. Biochemical Journal, 254 (3), 891-3. doi:10.1042/bj2540891

Frère, J.-M., & Joris, B. (1988). Beta-Lactamase-induced resistance. In P. Actor, L. Daneo-Moore, M. L. Higgins, M. R. J. Salton, ... G. D. Shockman (Eds.), Antibiotic Inhibition of Bacterial Cell Surface Assembly and Function (pp. 468-480). Washington,D.C., United States: American Society for Microbiology.

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Jacques, P., El Kharroubi, A., Joris, B., Dussenne, B., Thonon, F., Piras, G., Coyette, J., & Ghuysen, J.-M. (1988). Purification and Characterization of a β-lactam-Resistant Penicillin-Binding Protein from Enterococcus hirae (Streptococcus faecium). In P. Actor, L. Daneo-Moore, M. L. Higgins, M. R. J. Salton, ... G. D. Shockman (Eds.), Antibiotic Inhibition of Bacterial Cell Surface Assembly and Function (pp. 377-381). Washington, United States - District of Columbia: American Society for Microbiology.

Dehottay, P., Dusart, J., De Meester, F., Joris, B., Van Beeumen, J., Erpicum, T., Frère, J.-M., & Ghuysen, J.-M. (15 July 1987). Nucleotide sequence of the gene encoding the Streptomyces albus G β-lactamase precursor. European Journal of Biochemistry, 166 (2), 345-350. doi:10.1111/j.1432-1033.1987.tb13521.x

De Meester, F., Joris, B., Reckinger, G., Bellefroid-Bourguignon, C., Frère, J.-M., & Waley, S. G. (1987). Automated analysis of enzyme inactivation phenomena. Application to beta-lactamases and DD-peptidases. Biochemical Pharmacology, 36, 2393-2403. doi:10.1016/0006-2952(87)90609-5

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Duez, C., Fraipont, C., Joris, B., Dusart, J., Urdea, M. S., Martial, J., Frère, J.-M., & Ghuysen, J.-M. (1987). Primary structure of the Streptomyces R61 extracellular DD-peptidase. 1. Cloning into Streptomyces lividans and nucleotide sequence of the gene. European Journal of Biochemistry, 162, 509-518. doi:10.1111/j.1432-1033.1987.tb10669.x

Joris, B., De Meester, F., Galleni, M., Frère, J.-M., & Van Beeumen, J. (1987). The K1 beta-lactamase of Klebsiella pneumoniae. Biochemical Journal, 243 (2), 561-7. doi:10.1042/bj2430561

Joris, B., Jacques, P., Frère, J.-M., Ghuysen, J.-M., & Van Beeumen, J. (1987). Primary structure of the Streptomyces R61 extracellular DD-peptidase. 2. Amino acid sequence data. European Journal of Biochemistry, 162 (3), 519-524. doi:10.1111/j.1432-1033.1987.tb10670.x

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Joris, B., De Meester, F., Galleni, M., Reckinger, G., Coyette, J., Frère, J.-M., & Van Beeumen, J. (1985). The beta-lactamase of Enterobacter cloacae P99. Chemical properties, N-terminal sequence and interaction with 6 beta-halogenopenicillanates. Biochemical Journal, 228 (1), 241-8. doi:10.1042/bj2280241

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Joris, B., Van Beeumen, J., Casagrande, F., Gerday, C., Frère, J.-M., & Ghuysen, J.-M. (17 January 1983). The complete amino acid sequence of the Zn2+-containing D-alanyl-D-alanine-cleaving carboxypeptidase of streptomyces albus G. European Journal of Biochemistry, 130 (1), 53-69. doi:10.1111/j.1432-1033.1983.tb07116.x

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