Galimberti, M., Nucera, M. R., Bocchi, V. D., Conforti, P., Vezzoli, E., Cereda, M., Maffezzini, C., Iennaco, R., Scolz, A., Falqui, A., Cordiglieri, C., Cremona, M., Espuny Camacho, I. M., Faedo, A., Felsenfeld, D. P., Vogt, T. F., Ranzani, V., Zuccato, C., Besusso, D., & Cattaneo, E. (02 August 2024). Huntington's disease cellular phenotypes are rescued non-cell autonomously by healthy cells in mosaic telencephalic organoids. Nature Communications, 15 (1), 6534. doi:10.1038/s41467-024-50877-x |
Colinet, M.* , Chiver, I.* , Bonafina, A., Masset, G., Almansa Amores, D., Di Valentin, E., Twizere, J.-C., Nguyen, L.* , & Espuny Camacho, I. M.*. (2024). SARS-CoV2 infection triggers reactive astrocyte states and inflammatory conditions in long-term Human Cortical Organoids. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/316470. * These authors have contributed equally to this work. |
Colinet, M., Masset, G., Cambier, A., Coumans, B., Nguyen, L., & Espuny Camacho, I. M. (09 June 2023). Modelling human brain maturation and Alzheimer disease using 3D cortical organoids [Poster presentation]. Spring Meeting of the Belgian Society for Cell and Developmental Biology, Liège, Belgium. |
Colinet, M., Ghanavatinejad, F., Masset, G., Cambier, A., Helgueta Romero, S., Coumans, B., Engel, D., Nguyen, L., & Espuny Camacho, I. M. (2023). Modelling Human Brain Maturation Using 3D Cortical Organoids [Poster presentation]. BeSSCR/RBSCDB, Brussels, Belgium. |
Magni, M., Bossi, B., Conforti, P., Galimberti, M., Dezi, F., Lischetti, T., He, X., Barker, R. A., Zuccato, C., Espuny Camacho, I. M., & Cattaneo, E. (2022). Brain regional identity and cell type specificity landscape of human cortical organoid models. International Journal of Molecular Sciences. doi:10.3390/ijms232113159 |
Espuny Camacho, I. M. (November 2021). Stem Cell-based approaches in tissue engineering and Regenerative medicine [Paper presentation]. TERMIS 2021 6th World Congress, Maastricht, Netherlands. |
Dickinson Bocchi, V., Conforti, P., Bessuso, D., Cappadona, C., Ranzani, V., Bonnal, R. J. P., De Simone, M., Rossetti, G., Espuny Camacho, I. M., Faedo, A., Gervasoni, F., Vuono, R., He, X., Chen, J., Felsenfeld, D., Pavesi, G., Barker, R. A., Pagani, M., & Cattaneo, E. (07 May 2021). The coding and non-coding RNA single-cell atlas of the human fetal striatum. Science, 372 (6542). doi:10.1126/science.abf5759 |
Le Bail, R., Bonafina, A., Espuny Camacho, I. M.* , & Nguyen, L.*. (February 2021). Learning about cell lineage, cellular diversity and evolution of the human brain through stem cell models. Current Opinion in Neurobiology, 66, 166-177. doi:10.1016/j.conb.2020.10.018 * These authors have contributed equally to this work. |
Espuny Camacho, I. M. (October 2019). Human induced pluripotent stem cell models to study the human brain [Paper presentation]. Biomedica on the move 2019, Valorisation in Regenerative Medicine, Geleen, Netherlands. |
Espuny Camacho, I. M. (26 October 2018). Human pluripotent stem cell-derived cortical neurons for disease modeling and brain repair [Paper presentation]. 5th Annual Meeting of the Belgian Society for Stem Cell Research (BeSSCR), Leuven, Belgium. |
Espuny Camacho, I. M., Michelsen, K. A., Linaro, D., Bilheu, A., Acosta-Verdugo, S., Herpoel, A., Giugliano, M., Gaillard, A., & Vanderhaeghen, P. (2018). Human pluripotent stem-cell derived cortical neurons integrate functionally into the lesioned adult murine visual cortex in an area-specific way. Cell Reports. doi:10.1016/j.celrep.2018.04.094 |
Espuny Camacho, I. M. (26 September 2017). HUMAN PLURIPOTENT STEM CELL-DERIVED CORTICAL NEURONS FOR DISEASE MODELING AND CORTICAL REPAIR [Paper presentation]. STEM CELLS FOR NEURODEGENERATIVE DISEASES, Rome, Italy. |
Espuny Camacho, I. M., Arranz, A., Fiers, M., Snellinx, A., Ando, K., Munck, S., Bonnefont, J., Lambot, L., Corthout, N., Omodho, L., Vanden Eynden, E., Radaelli, E., Tesseur, I., Wray, S., Ebneth, A., Hardy, J., Leroy, K., Brion, J., Vanderhaeghen, P., & De Strooper, B. (2017). Hallmarks of Alzheimer’s disease in stem cell-derived human neurons transplanted into mouse brain. Neuron. doi:10.1016/j.neuron.2017.02.001 |
Espuny Camacho, I. M. (11 September 2015). An in vivo humanized model for Alzheimer’s disease from pluripotent stem cells [Paper presentation]. EMBO meeting Cell therapy today: Achievements, hopes and hype, Manchester, United Kingdom. |
Michelsen, K., Acosta-Verdugo, S., Benoit-Marand, M., Espuny Camacho, I. M., Gaspard, N., Saha, B., Gaillard, A., & Vanderhaeghen, P. (2015). Area-specific reestablishment of damaged circuits in the adult cerebral cortex by cortical neurons derived from mouse embryonic stem cells. Neuron. doi:10.1016/j.neuron.2015.02.001 |
Nageshappa, S., Carromeu, C., Trujillo, Mesci, P., Espuny Camacho, I. M., Pasciuto, E., Vanderhaeghen, P., Verfaille, C., Raitano, S., Kumar, A., Carvalho, C., Bagni, C., Ramocki, M., Araujo, B., Torres, L., Lupski, J., Van Esch, H., & Muotri, A. (2015). Altered neuronal network in a human MECP2 duplication model. Molecular Psychiatry. doi:10.1038/mp.2015.128 |
Raitano, S., Ordovàs, L., De Muynck, K., Guo, W., Espuny Camacho, I. M., Geraerts, M., Khurana, S., Vanuytsel, K., Tóth, B., Voets, T., Vandenberghe, R., Cathomen, T., Van Den Bosch, Vanderhaeghen, P., Van Damme, P., & Verfaille, C. (2015). Restoration of progranulin expression rescues cortical neuron generation in induced pluripotent stem cell model of frontotemporal dementia by mitigating increased WNT signaling. Stem Cell Reports. doi:10.1016/j.stemcr.2014.12.001 |
Espuny Camacho, I. M. (29 September 2014). Pyramidal neurons derived from human pluripotent stem cells mature to form functional synapses in vitro and integrate e ciently into mouse brain circuits in vivo [Paper presentation]. SYNERG of young scientists Munich Cluster for Systems Neurology, Munich, Germany. |
Espuny Camacho, I. M. (23 September 2014). Pyramidal Neurons Derived from Human Pluripotent Stem Cells Integrate Efficiently into Mouse Brain Circuits In Vivo [Paper presentation]. The company of Biologists workshop From Stem cells to Human development. |
Espuny Camacho, I. M. (12 September 2014). Pyramidal Neurons Derived from Human Pluripotent Stem Cells Integrate Efficiently into Mouse Brain Circuits In Vivo [Paper presentation]. 1st Meeting of the Belgian Society for Stem Cell Research (BeSSCR) Stem cells: ready for the transition from bench to bedside?, Ghent, Belgium. |
Van den Aamele, J., Tiberi, L., Vanderehaeghen, P., & Espuny Camacho, I. M. (2014). Thinking out of the dish: What to learn about cortical development using pluripotent stem cells. Trends in Neuroscience. doi:10.1016/j.tins.2014.03.005 |
Espuny Camacho, I. M. (22 July 2013). Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo [Paper presentation]. Department of Stem Cell and Regenerative Biology Harvard University, Cambridge, United States. |
Espuny Camacho, I. M. (24 June 2013). hPSC-derived corticogenesis generates pyramidal neurons that integrate into brain networks in vivo [Paper presentation]. 23rd ESACT Meeting, Lille, France. |
Espuny Camacho, I. M., Michelsen, K. A., Gall, D., Linaro, D., Hasche, A., Bonnefont, J., Bali, C., Orduz, D., Bilheu, A., Herpoel, A., Lambert, N., Gaspard, N., Perón, S., Schiffmann, S., Giugliano, M., Gaillard, A., & Vanderhaeghen. (2013). Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo. Neuron. doi:10.1016/j.neuron.2012.12.011 |
Espuny Camacho, I. M. (20 December 2012). Corticogenesis from human pluripotent stem cells leads to the generation of pyramidal neurons with diverse and complex hodological properties [Paper presentation]. 8th Christmas Annual Meeting. Instituto de Neurociencias, Alicante, Spain, Alicante, Spain. |
Espuny Camacho, I. M. (20 December 2012). Corticogenesis from human pluripotent stem cells leads to the generation of pyramidal neurons with diverse and complex hodological properties [Paper presentation]. 8th Christmas Annual Meeting Instituto de Neurociencias, Alicante, Spain, Alicante, Spain. |
Espuny Camacho, I. M. (14 December 2012). Corticogenesis from human pluripotent stem cells leads to the generation of pyramidal neurons with diverse and complex hodological properties [Paper presentation]. XIVth BELACT Meeting Advanced models of (stem) cells in toxicology, pharmacology, safety assessment, and cell therapy, Brussels, Belgium. |
Espuny Camacho, I. M., Dominguez, D., Merchiers, P., Van Rompaey, L., Selkoe, D., & De Strooper, B. (2010). Peroxisome Proliferator-Activated Receptor gamma enhances the activity of a insulin degrading enzyme-like metalloprotease for amyloid-beta clearance. Journal of Alzheimer's Disease. doi:10.3233/JAD-2010-091633 |
Gaspard, N., Bouschet, T., Hourez, R., Dimidschstein, J., Naeije, G., van den Ameele, J., Espuny Camacho, I. M., Herpoel, A., Passante, L., Schiffmann, S. N., Gaillard, A., & Vanderhaeghen, P. (2008). An intrinsic mechanism of corticogenesis from embryonic stem cells. Nature. doi:10.1038/nature07287 |
Dominguez, D., Tournoy, J., Hartmann, D., Huth, T., Cryns, K., Deforce, S., Serneels, L., Espuny Camacho, I. M., Marjaux, E., Craessaerts, K., Roebroek, A., Schawke, M., D'Hooge, R., Bach, P., Kalinke, U., Moechars, D., Alzheimer, C., Reiss, K., Saftig, P., & De Strooper, B. (2005). Phenotypic and biochemical analysis of BACE1-and BACE2- deficient mice. Journal of Biological Chemistry. doi:10.1074/jbc.M505249200 |
Espuny Camacho, I. M., Serneels, L., Spittaels, K., Merchiers, P., Dominguez, D., & De Strooper, B. (2004). Peroxisome Proliferator-Activated Receptor gamma induces a clearance mechanism for the amyloid-beta peptide. Journal of Neuroscience. doi:10.1523/JNEUROSCI.3987-04.2004 |