Pedrinazzi, E., Blouin, S., Pyka, G., Béché, A., Hartmann, M., Simar, A., & Ruffoni, D. (02 July 2024). THE ROLE OF MINERAL HETEROGENEITY AND MATERIAL ANISOTROPY ON TRABECULAR BONE MECHANICS [Paper presentation]. 29th Congress of the European Society of Biomechanics, Edinburgh, United Kingdom. |
Malerba, A., Tits, A., Volders, T., Vena, P., & Ruffoni, D. (July 2024). DO STIFFNESS GRADIENTS PLAY A ROLE IN THE PROTECTION OF THE TENDON-TO-BONE INTERFACE? A COMPUTATIONAL STUDY [Poster presentation]. 29th Congress of the European Society of Biomechanics, Edinburgh, United Kingdom. |
Gattin, M., Bochud, N., Grossman, Q., Ruffoni, D., Rosi, G., & Naili, S. (15 February 2024). Ultrasound monitoring of multiphase architectured media: Bandgap tracking via the measurement of the reflection coefficient. Applied Acoustics, 217, 109844. doi:10.1016/j.apacoust.2023.109844 |
Cantamessa, A., Blouin, S., Amini, S., Rummler, M., Berzlanovich, A., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (16 November 2023). Mineralization and Mechanical Insights of Cement Lines in Human Osteonal Bone [Paper presentation]. Annual Benelux meeting of IEEE Engineering in Medicine and Biology Society and 21st National Day of Biomedical Engineering, Bruxelles, Belgium. |
Cantamessa, A., Blouin, S., Amini, S., Rummler, M., Berzlanovich, A., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (13 October 2023). A Multimodal Analysis of Cement Lines in Human Osteonal Bone [Poster presentation]. Annual Meeting of the American Society of Bone and Mineral Research, Vancouver, Canada. |
Tits, A., Blouin, S., Rummler, M., Kaux, J.-F., Drion, P., van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (August 2023). Structural and functional heterogeneity of mineralized fibrocartilage at the Achilles tendon-bone insertion. Acta Biomaterialia, 166, 409 - 418. doi:10.1016/j.actbio.2023.04.018 |
Cantamessa, A., Blouin, S., Amini, S., Rummler, M., Berzlanovich, A., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (27 July 2023). Mineral Content and Mechanical Properties of Cement Lines in Human Osteonal Bone [Paper presentation]. European Society of Biomechanics Conference, Maastricht, Netherlands. |
Müller, L., Tits, A., Weinkamer, R., Drion, P., Dall'Ara, E., Van Lenthe, G. H., & Ruffoni, D. (10 July 2023). Changes in subchondral bone microstructure and shape with age in tibial knee [Paper presentation]. 28th Congress of the European Society of Biomechanics, Maastricht, Netherlands. |
Lew, A. J., Stifler, C. A., Tits, A., Schmidt, C. A., Scholl, A., Cantamessa, A., Müller, L., Delaunois, Y., Compère, P., Ruffoni, D., Buehler, M. J., & Gilbert, P. U. P. A. (July 2023). A Molecular-Scale Understanding of Misorientation Toughening in Corals and Seashells. Advanced Materials, 35 (28), 2300373. doi:10.1002/adma.202300373 |
Tits, A., Blouin, S., Rummler, M., Kaux, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (31 March 2023). Bone-fibrocartilage crosstalk and osteocyte lacuno-canalicular network at the tendon-bone insertion [Paper presentation]. European Society of Biomechanics Conference, Maastricht, Netherlands. |
Delaunois, Y., Tits, A., Grossman, Q., Smeets, S., Malherbe, C., Eppe, G., van Lenthe, G. H., Ruffoni, D.* , & Compère, P.*. (2023). Design Strategies of the Mantis Shrimp Spike: How the Crustacean Cuticle Became a Remarkable Biological Harpoon? Natural Sciences. doi:10.22541/au.167199666.61851387/v1 * These authors have contributed equally to this work. |
Saldívar, M. C., Salehi, S., Veeger, R. P. E., Fenu, M., Cantamessa, A., Klimopoulou, M., Talò, G., Moretti, M., Lopa, S., Ruffoni, D., van Osch, G. J. V. M., Fratila-Apachitei, L. E., Doubrovski, E. L., Mirzaali, M. J., & Zadpoor, A. A. (2023). Rational positioning of 3D printed micro-bricks to realize high-fidelity, multi-functional soft-hard interfaces. Cell Reports. Physical Science. doi:10.1101/2023.01.21.525002 |
Lew, A. J., Stifler, C. A., Cantamessa, A., Tits, A., Ruffoni, D., Gilbert, P. U. P. A., & Buehler, M. J. (2023). Deep learning virtual indenter maps nanoscale hardness rapidly and non-destructively, revealing mechanism and enhancing bioinspired design. Matter, 6 (6), 1975-1991. doi:10.1016/j.matt.2023.03.031 |
Malerba, A., Tits, A., Volders, T., Vena, P., & Ruffoni, D. (2023). A COMPUTATIONAL INVESTIGATION OF THE TENDON-TO-BONE INSERTION: THE ROLE OF TISSUE ANISOTROPY [Paper presentation]. 28th Congress of the European Society of Biomechanics, Maastricht, Netherlands. |
Grossman, Q., Varga, P., & Ruffoni, D. (25 October 2022). Architectured Interfaces in Bimaterial Attachments [Paper presentation]. Workshop of the IRP Coss&Vita, Metamaterials and biomechanics : from bio-inspiration to bio-metamaterials, Arpino, Italy. |
Volders, T., Zorzetto, L., Razi, H., Weinkamer, R., & Ruffoni, D. (28 September 2022). Designing Architectured Materials with Tunable Damage Behavior Inspired by Osteonal Bone [Poster presentation]. Imparting Intelligence in and Through Self-Learning Materials and Structures, Ventura, United States - California. |
Gattin, M., Bochud, N., Rosi, G., Grossman, Q., Ruffoni, D., & Naili, S. (23 September 2022). Ultrasound characterization of the viscoelastic properties of additively manufactured photopolymer materials. Journal of the Acoustical Society of America, 152 (3), 1901-1912. doi:10.1121/10.0014180 |
Delaunois, Y., Smeets, S., Tits, A., Ruffoni, D., & Compère, P. (22 September 2022). The spiky exoskeleton of the spearing mantis shrimp; comparative study of 3 puncturing bio-tools [Paper presentation]. Benelux Congress of Zoology, Kortrijk, Belgium. |
Volders, T., Zorzetto, L., Razi Hajar, Weinkamer Richard, & Ruffoni, D. (03 August 2022). How to protect a weak spot inside a load-bearing architecture material: a lesson from bone [Paper presentation]. WCCM-APCOM Yokohama 2022, 15th World Congress on Computational Mechanics & 8th Asian Pacific Congress on Computational Mechanics, Yokohama, Japan. |
Cantamessa, A., Muraro, P., Delaunois, Y., Compère, P., Blouin, S., Hartmann, M. A., & Ruffoni, D. (27 June 2022). Mineral content and biomechanical properties of fibrolamellar bone [Paper presentation]. European Society of Biomechanics Conference, Porto, Portugal. |
Habets, T., Siragusa, F., Müller, A. J., Grossman, Q., Ruffoni, D., Grignard, B., & Detrembleur, C. (07 June 2022). Facile construction of functional poly(monothiocarbonate) copolymers under mild operating conditions. Polymer Chemistry, 13 (21), 3076-3090. doi:10.1039/d2py00307d |
De Noni, L., Zorzetto, L., Briatico-Vangosa, F., Rink, M., Ruffoni, D., & Andena, L. (April 2022). Modelling the interphase of 3D printed photo-cured polymers. Composites. Part B, Engineering, 234, 109737. doi:10.1016/j.compositesb.2022.109737 |
Tits, A., Blouin, S., Rummler, M., KAUX, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (31 March 2022). Biomechanics and mechanobiology of mineralized fibrocartilage at the tendon-bone attachment [Paper presentation]. European Society of Biomechanics Conference, Porto, Portugal. |
Tits, A., Blouin, S., Rummler, M., KAUX, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (21 March 2022). Combining high-resolution imaging techniques to reveal the structure and function of fibrocartilage at the tendon-bone insertion [Paper presentation]. International Workshop on Quantitative Musculoskeletal Imaging, in combination with 9th International Symposium on Ultrasonic Characterization of Bone, Noordwijck, Netherlands. |
Aghaei, A., Bochud, N., Rosi, G., Grossman, Q., Ruffoni, D., & Naili, S. (March 2022). Ultrasound characterization of bioinspired functionally graded soft-to-hard composites: Experiment and modeling. Journal of the Acoustical Society of America, 151 (3), 1490. doi:10.1121/10.0009630 |
Müller, L., Tits, A., Plougonven, E., Drion, P., Dall'Ara, E., Léonard, A., Van Lenthe, H., & Ruffoni, D. (2022). Architecture of the trabecular bone between the metaphyseal and subchondral parts in the knee joint [Paper presentation]. 20th National Day of Biomedical Engineering, Bruxelles, Belgium. |
Müller, L., Tits, A., Plougonven, E., Drion, P., Dall'Ara, E., Van Lenthe, G. H., & Ruffoni, D. (2022). Differences between subchondral and trabecular bone microporosities beneath the bone-cartilage interface at the knee joint [Poster presentation]. 15th Congress of the International Society of Bone Morphometry, Odense, Denmark. |
Grossman, Q., Varga, P., & Ruffoni, D. (29 December 2021). Voxel 3D printing and computer simulations to prototype bimaterial attachments based on local interface patterning [Paper presentation]. 2021 MRS Fall Meeting, Boston, United States - Massachusetts. |
Delaunois, Y., Smeets, S., Malherbe, C., Eppe, G., Lecchini, D., Ruffoni, D., & Compère, P. (06 November 2021). Structure and mineralization of the spearing mantis shrimp (Stomatopoda; Lysiosquillina maculata) body and spike cuticles. Journal of Structural Biology, 213 (4). doi:10.1016/j.jsb.2021.107810 |
Tits, A., Blouin, S., Rummler, M., KAUX, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (02 November 2021). Biomechanical and biological aspects of mineralized fibrocartilage at the tendon-bone interface: a multi-modal analysis [Paper presentation]. Bones and Teeth Gordon Research Conference, Ventura, United States. |
Tits, A., Blouin, S., Rummler, M., KAUX, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (23 October 2021). A multimodal investigation of mineralized fibrocartilage at the tendon-bone insertion [Paper presentation]. Annual retreat of the Ludwig Boltzmann Institute of Osteology. |
Tits, A., Plougonven, E., Blouin, S., Hartmann, M. A., Kaux, J.-F., Drion, P., Fernandez, J., van Lenthe, G. H., & Ruffoni, D. (August 2021). Local anisotropy in mineralized fibrocartilage and subchondral bone beneath the tendon-bone interface. Scientific Reports, 11, 16534. doi:10.1038/s41598-021-95917-4 |
Tits, A., Blouin, S., KAUX, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M., & Ruffoni, D. (13 July 2021). Microstructural anisotropy and material gradients in mineralized fibrocartilage at the tendon-bone insertion [Paper presentation]. 26th Congress of the European Society of Biomechanics, Milan (Online), Italy. |
Tits, A., & Ruffoni, D. (2021). Joining soft tissues to bone: Insights from modeling and simulations. Bone Reports. doi:10.1016/j.bonr.2020.100742 |
Tits, A., Varga, P., Volders, T., Kaux, J.-F., Plougonven, E., Fernandez, J., Drion, P., Van Lenthe, G. H., & Ruffoni, D. (October 2020). Local adaptation of bone micro-structure and canal network to tendon insertion investigated by image-based micro-FE simulations. Bone Reports, 13, 100392. doi:10.1016/j.bonr.2020.100393 |
Tits, A., Varga, P., KAUX, J.-F., Plougonven, E., Fernandez, J., Drion, P., Van Lenthe, G. H., & Ruffoni, D. (24 June 2020). Soft-to-hard biological interfaces: microstructural and micromechanical investigation of the tendon-bone attachment [Paper presentation]. European Calcified Tissue Society Digital Masterclass. |
Mirzaali, M. J., Nava, A. H. D. L., Gunashekar, D., Nouri-Goushki, M., Veeger, R. P. E., Grossman, Q., Angeloni, L., Ghatkesar, M. K., Fratila-Apachitei, L. E., Ruffoni, D., Doubrovski, E. L., & Zadpoor, A. A. (2020). Mechanics of bioinspired functionally graded soft-hard composites made by multi-material 3D printing. Composite Structures, 237, 111867. doi:10.1016/j.compstruct.2020.111867 |
Zorzetto, L., Andena, L., Briatico-Vangosa, F., De Noni, L., Thomassin, J.-M., Jérôme, C., Grossman, Q., Mertens, A., Weinkamer, R., Rink, M., & Ruffoni, D. (2020). Properties and role of interfaces in multimaterial 3D printed composites. Scientific Reports, 10 (1), 22285. doi:10.1038/s41598-020-79230-0 |
Tits, A., KAUX, J.-F., Plougonven, E., Fernandez, J., Drion, P., Van Lenthe, G. H., & Ruffoni, D. (17 December 2019). Microstructural and micromechanical investigation of the tendon-bone attachment [Paper presentation]. 8th International Conference on Mechanics of Biomaterials and Tissues (ICMOBT), Waikoloa Beach, Hawaii, United States. |
Delaunois, Y., Malherbe, C., Tits, A., Ruffoni, D., & Compère, P. (10 September 2019). Reinforcement and adaptation of the mantis shrimp spike: how crustacean cuticle became a perfect harpoon? [Paper presentation]. 15th International Symposium on Biomineralization, Munich, Germany. |
Tits, A., KAUX, J.-F., Fernandez, J., Drion, P., Van Lenthe, G. H., & Ruffoni, D. (July 2019). Structural and mechanical analysis of calcaneus bone at the Achilles tendon insertion site [Paper presentation]. 25th World Congress of the European Society of Biomechanics – ESB 2019, Vienne, Austria. |
Li, Z., Betts, D., Kuhn, G., Schirmer, M., Müller, R., & Ruffoni, D. (2019). Mechanical regulation of bone formation and resorption around implants in a mouse model of osteopenic bone. Journal of the Royal Society, Interface, 16 (152), 20180667. doi:10.1098/rsif.2018.0667 |
Zorzetto, L., & Ruffoni, D. (2019). Wood-Inspired 3D-Printed Helical Composites with Tunable and Enhanced Mechanical Performance. Advanced Functional Materials, 29 (1), 1805888. doi:10.1002/adfm.201805888 |
Ruffoni, D. (12 September 2018). Mechanical Properties of Interfaces in 3D Printed Polymer Composites Investigated by Nanoindentation [Paper presentation]. Indentation 2018, Liege, Belgium. |
Ruffoni, D. (28 June 2018). 3D Printing of Bio-inspired Helical Composites with Enhanced Failure Resistance [Paper presentation]. First International Conference on Materials, Mimicking, Manufacturing from and for Bio Application. |
Zorzetto, L., & Ruffoni, D. (19 March 2018). Biomechanical role of thin reinforcements layers in helicoidal composites inspired by wood-cells: from field study to transfer to 3D printed composites [Poster presentation]. International School and Conference on Biological Material Science - 4th Euro Bio-inspired Materials 2018, Potsdam, Germany. |
Zorzetto, L., & Ruffoni, D. (22 September 2017). Mimicking helicoidal biological materials to improve strength of synthetic composites [Paper presentation]. European Congress and Exhibition on Advanced Materials and Processes 2017 - Euromat2017, Thessaloniki, Greece. |
Li, Z., Betts, D., Kuhn, G., Müller, R., & Ruffoni, D. (2017). Mechanical loading therapy increases bone formation while reducing bone resorption following implantation in a mouse model of postmenopausal osteoporosis. JBMR Plus. |
Li, Z., Kuhn, G., Schirmer, M., Müller, R., & Ruffoni, D. (2017). Impaired bone formation in ovariectomized mice reduces implant integration as indicated by longitudinal in vivo micro-computed tomography. PLoS ONE, 12 (9), 1-22. doi:10.1371/journal.pone.0184835 |
Li, Z., Müller, R., & Ruffoni, D. (2017). Bone remodeling and mechanobiology around implants: Insights from small animal imaging. Journal of Orthopaedic Research. doi:10.1002/jor.23758 |
Ruffoni, D., & van Lenthe, H. (2017). Finite Element Analysis in Bone Research: A Computational Method Relating Structure to Mechanical Function. In Comprehensive Biomaterials II. Elsevier. doi:10.1016/B978-0-12-803581-8.09798-8 |
Zorzetto, L., Briatico Vangosa, F., Rink, M., Andena, L., & Ruffoni, D. (2017). A multiscale analysis of interface properties in 3D printed composites [Paper presentation]. European Congress and Exhibition on Advanced Materials and Processes. |
Zorzetto, L., & Ruffoni, D. (2017). Re-entrant inclusions in cellular solids: From defects to reinforcements. Composite Structures, 176, 195 - 204. doi:10.1016/j.compstruct.2017.05.039 |
Zorzetto, L., Thomassin, J.-M., Jérôme, C., & Ruffoni, D. (25 October 2016). Mechanical Response of 3D Printed Biomimetic Helical Fiber Composites [Paper presentation]. Engineering Mechanics Institute (EMI) International conference, Metz, France. |
Zorzetto, L., Rink, M., Briatico Vangosa, F., Andena, L., & Ruffoni, D. (07 September 2016). Interfaces in multi-material architectures fabricated by polyjet printing [Paper presentation]. 15th European Mechanics of Materials Conference, Brussels, Belgium. |
Zorzetto, L., & Ruffoni, D. (07 September 2016). Auxetic inclusions in cellular solids allow tailoring Poisson’s ratio and enhancing stiffness [Paper presentation]. 15th European Mechanics of Materials Conference, Brussels, Belgium. |
Li, Z., Betts, D., Kuhn, G., Müller, R., & Ruffoni, D. (28 July 2016). Effect of Mechanical Loading on Peri-Implant Bone Remodeling Measured with Time-Lapsed Imaging and Finite Element Analysis [Paper presentation]. 12th World Congress of Computational Mechanics and 6th Asia-Pacific Congress on Computational Mechanics, Seoul, South Korea. |
Li, Z., Betts, D., Kuhn, G., & Ruffoni, D. (July 2016). The mechanical control of peri-implant bone remodeling investigated by in vivo imaging and in silico modeling [Paper presentation]. European Society of Biomechanics (ESB) and the Société de Biomécanique (SB) Congress, Lyon, France. |
Zorzetto, L., Thomassin, J.-M., Jérôme, C., & Ruffoni, D. (February 2016). Bioinspired Helicoidal Composites with Tunable Mechanical Behavior by 3-Dimensional Multi-material Printing [Paper presentation]. Gordon Research Conference on Multifunctional Materials and Structures, Ventura, United States. |
Zorzetto, L., & Ruffoni, D. (September 2015). Remarkable stiffness enhancement in multilayered honeycombs obtained through periodic variations in Poisson's ratio [Paper presentation]. Euromat2015, Warsaw, Poland. |
Collet, M., Bruggi, M., Bauduin, S., Ruffoni, D., & Duysinx, P. (09 July 2015). Simplified fatigue resistance in mechanical engineering using topology optimization [Paper presentation]. 9th European Solid Mechanics Conference, Madrid, Spain. |
Ruffoni, D., Christen, P., Scherf, H., & Weinkamer, R. (April 2015). Wolff’s Law and the Interplay between Bone Structure and External Loading. BoneKEy Reports, 13. doi:10.1038/bonekey.2015.40 |
Li, Z., Kuhn, G., Müller, R., & Ruffoni, D. (2015). Cortical bone response following implantation: changes in bone remodeling and mechanical regulation on periosteal and endosteal surfaces. BoneKEy Reports. |
Li, Z., Kuhn, G., von Salis-Soglio, M., Cooke, S. J., Schirmer, M., Mueller, R., & Ruffoni, D. (2015). In vivo monitoring of bone architecture and remodeling after implant insertion: The different responses of cortical and trabecular bone. BONE, 81, 468-477. doi:10.1016/j.bone.2015.08.017 |
Maurer, M., Weinkamer, R., Müller, R., & Ruffoni, D. (2015). Does mechanical stimulation really protect the architecture of trabecular bone? A simulation study. Biomechanics and Modeling in Mechanobiology. doi:10.1007/s10237-014-0637-x |
Zwahlen, A., Christen, D., Ruffoni, D., Schneider, P., Schmoelz, W., & Mueller, R. (2015). Inverse Finite Element Modeling for Characterization of Local Elastic Properties in Image-Guided Failure Assessment of Human Trabecular Bone. Journal of Biomechanical Engineering, 137 (1). doi:10.1115/1.4028991 |
Li, Z., von Salis Soglio, M., Kuhn, G., Müller, R., & Ruffoni, D. (07 July 2014). The Interplay Between Cortical and Trabecular Bone Following Implant Insertion Investigated by In Vivo Micro-Computed Tomography [Paper presentation]. 7th World Congress of Biomechanics, Boston, United States. |
Ruffoni, D., Weinkamer, R., Kuhn, G., & Müller, R. (July 2014). Kinetics of Bone Mineralization and Demineralization in Postmenopausal Osteoporosis [Paper presentation]. 7th World Congress of Biomechanics, Boston, United States. |
Bounoure, L., Ruffoni, D., Mueller, R., Kuhn, G. A., Bourgeois, S., Devuyst, O., & Wagner, C. A. (2014). The Role of the Renal Ammonia Transporter Rhcg in Metabolic Responses to Dietary Protein. Journal of the American Society of Nephrology, 25 (9), 2040-2052. doi:10.1681/ASN.2013050466 |
Donaldson, F., Ruffoni, D., Schneider, P., Alina, L., Zwahlen, A., Pankaj, P., & Mueller, R. (2014). Modeling microdamage behavior of cortical bone. Biomechanics and Modeling in Mechanobiology, 13 (6), 1227-1242. doi:10.1007/s10237-014-0568-6 |
Zermatten, E., Vetsch, J. R., Ruffoni, D., Hofmann, S., Mueller, R., & Steinfeld, A. (2014). Micro-Computed Tomography Based Computational Fluid Dynamics for the Determination of Shear Stresses in Scaffolds Within a Perfusion Bioreactor. Annals of Biomedical Engineering, 42 (5), 1085-1094. doi:10.1007/s10439-014-0981-0 |
Li, Z., von Salis-Soglio, M., Cooke, S., Schirmer, M., van Lenthe, H., Müller, R., & Ruffoni, D. (September 2013). Time-lapsed in vivo monitoring of peri-implant bone remodeling in a mouse model [Paper presentation]. International Conference on Computational Bioengineering (ICCB 2013), Leuven, Belgium. |
Lambers, F. M., Koch, K., Kuhn, G., Ruffoni, D., Weigt, C., Schulte, F. A., & Mueller, R. (2013). Trabecular bone adapts to long-term cyclic loading by increasing stiffness and normalization of dynamic morphometric rates. BONE, 55 (2), 325-334. doi:10.1016/j.bone.2013.04.016 |
Lau, K.-H. W., Baylink, D. J., Zhou, X.-D., Rodriguez, D., Bonewald, L. F., Li, Z., Ruffoni, D., Mueller, R., Kesavan, C., & Sheng, M. H.-C. (2013). Osteocyte-derived insulin-like growth factor I is essential for determining bone mechanosensitivity. American Journal of Physiology - Endocrinology and Metabolism, 305 (2), 271-E281. doi:10.1152/ajpendo.00092.2013 |
Levchuk, A., Sommer, R., Badilatti, S. D., Schulte, F. A., Ruffoni, D., Weigt, C., Kuhn, G., & Mueller, R. (2013). In silico simulations of bone remodeling with improved parameter estimation from local strains and dynamic morphometry in vivo. Journal of Bone and Mineral Research, 28 (1). |
Lukas, C., Ruffoni, D., Lambers, F. M., Schulte, F. A., Kuhn, G., Kollmannsberger, P., Weinkamer, R., & Mueller, R. (2013). Mineralization kinetics in murine trabecular bone quantified by time-lapsed in vivo micro-computed tomography. BONE, 56 (1), 55-60. doi:10.1016/j.bone.2013.05.005 |
Ruffoni, D., Kohler, T., Voide, R., Wirth, A. J., Donahue, L. R., Mueller, R., & van Lenthe, G. H. (2013). High-throughput quantification of the mechanical competence of murine femora - A highly automated approach for large-scale genetic studies. BONE, 55 (1), 216-221. doi:10.1016/j.bone.2013.02.015 |
Ruffoni, D., Weigt, C., Fattorini, E., Levchuk, A., Schulte, F., Kuhn, G., & Müller, R. (2013). The spatial relationship between bone formation and bone resorption in healthy and ovariectomized mice treated with PTH, bisphosphonate or mechanical loading. Bone (DOI:10.1530/boneabs.1.PP437). |
Schulte, F. A., Ruffoni, D., Lambers, F. M., Christen, D., Webster, D. J., Kuhn, G., & Mueller, R. (2013). Local Mechanical Stimuli Regulate Bone Formation and Resorption in Mice at the Tissue Level. PLoS ONE, 8 (4), 62172-12. doi:10.1371/journal.pone.0062172 |
Schulte, F. A., Zwahlen, A., Lambers, F. M., Kuhn, G., Ruffoni, D., Betts, D., Webster, D. J., & Mueller, R. (2013). Strain-adaptive in silico modeling of bone adaptation - A computer simulation validated by in vivo micro-computed tomography data. BONE, 52 (1), 485-492. doi:10.1016/j.bone.2012.09.008 |
Zwahlen, A., Christen, D., Ruffoni, D., Schneider, P., Schmoelz, W., & Mueller, R. (2013). Image-guided failure assessment of human trabecular bone - Inverse finite element modelling for characterization of elastic properties. Biomedizinische Technik. Biomedical Engineering, 58 (1). doi:10.1515/bmt-2013-4114 |
Ruffoni, D., Maurer, M., Weinkamer, R., & Müller, R. (September 2012). The role of disorder in the mechanical control of trabecular bone as a cellular solid structure [Paper presentation]. 6th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012), Vienna, Austria. |
Ruffoni, D., Maurer, M., Weinkamer, R., & Müller, R. (July 2012). A beam lattice model to investigate basic aspects of bone remodeling [Paper presentation]. 18th Congress of the European Society of Biomechanics (ESB), Lisbon, Portugal. |
Ruffoni, D., Mueller, R., & van Lenthe, G. H. (2012). Mechanisms of reduced implant stability in osteoporotic bone. Biomechanics and Modeling in Mechanobiology, 11 (3-4), 313-323. doi:10.1007/s10237-011-0312-4 |
Ruffoni, D., Schulte, F. A., Lambers, F. M., Webster, D., Kuhn, G., & Mueller, R. (2012). Experimental quantification of Wolff's law in an in vivo loading model. BONE, 50 (1), 125-S125. doi:10.1016/j.bone.2012.02.387 |
Ruffoni, D.* , Wirth, A. J.* , Steiner, J. A., Parkinson, I. H., Mueller, R., & van Lenthe, G. H. (2012). The different contributions of cortical and trabecular bone to implant anchorage in a human vertebra. BONE, 50 (3), 733-738. doi:10.1016/j.bone.2011.11.027 * These authors have contributed equally to this work. |
Schulte, F. A., Weigt, C., Ruffoni, D., Lambers, F. M., Levchuk, A., Webster, D. J., Kuhn, G., & Mueller, R. (2012). Parathyroid hormone but not bisphosphonate therapy interferes with the local mechanoregulatory mechanism in trabecular bone. BONE, 50 (1), 40-S40. doi:10.1016/j.bone.2012.02.105 |
Zickler, G. A., Ruffoni, D., Dunlop, J. W. C., Elbaum, R., Weinkamer, R., Fratzl, P., & Antretter, T. (2012). Finite Element Modeling of the Cyclic Wetting Mechanism in the Active Part of Wheat Awns. Biointerphases, 7 (1-4), 42-9. doi:10.1007/s13758-012-0042-x |
Lukas, C., Kollmannsberger, P., Ruffoni, D., Roschger, P., Fratzl, P., & Weinkamer, R. (2011). The Heterogeneous Mineral Content of Bone-Using Stochastic Arguments and Simulations to Overcome Experimental Limitations. Journal of Statistical Physics, 144 (2), 316-331. doi:10.1007/s10955-011-0209-8 |
Lukas, C., Kollmannsberger, P., Ruffoni, D., Roschger, P., Fratzl, P., & Weinkamer, R. (2011). The effect of a disturbed mineralization process on the bone mineralization density distribution (BMDD). BONE, 48 (2), 181-S182. doi:10.1016/j.bone.2011.03.422 |
Lukas, C., Lambers, F., Ruffoni, D., Schulte, F. A., Kuhn, G. A., Kollmannsberger, P., Weinkamer, R., & Mueller, R. (2011). Quantification of the interplay between mineralization and remodeling in trabecular bone assessed by in vivo micro-computed tomography. BONE, 48 (2), 205-S205. doi:10.1016/j.bone.2011.03.467 |
Ruffoni, D., Steiner, J., Wirth, A., Mueller, T., Goldhahn, J., Müller, R., & van Lenthe, H. (January 2011). How does cement augmentation increase the mechanical properties of trabecular bone? [Paper presentation]. 57th Annual Meeting of the Orthopaedic Research Society, Long beach, United States. |
Ruffoni, D., & van Lenthe, H. (2011). Finite element analysis in bone research: a computational method relating structure to mechanical function. In Comprehensive Biomaterials. Elsevier. |
Kallai, I.* , van Lenthe, G. H.* , Ruffoni, D., Zilberman, Y., Muller, R., Pelled, G., & Gazit, D. (2010). Quantitative, structural, and image-based mechanical analysis of nonunion fracture repaired by genetically engineered mesenchymal stem cells. Journal of Biomechanics, 43 (12), 2315-2320. doi:10.1016/j.jbiomech.2010.04.031 * These authors have contributed equally to this work. |
Mader, K., Schneider, P., Ruffoni, D., van Lenthe, G. H., Thiran, J.-P., Mueller, R., & Stampanoni, M. (2010). Automated, High-Throughput, Multi-scale Assessment of Bone Morphology and Bone Competence. IFMBE Proceedings, 31, 841-843. doi:10.1007/978-3-642-14515-5_214 |
Ruffoni, D., Dunlop, J. W. C., Fratzl, P., & Weinkamer, R. (2010). Effect of minimal defects in periodic cellular solids. Philosophical Magazine, 90 (13), 1807-1818. doi:10.1080/14786430903571404 |
Ruffoni, D., Voide, R., Kohler, T., Donahue, L. R., Mueller, R., & van Lenthe, G. H. (2010). BONE MECHANICAL COMPETENCE IS A HIGHLY HERITABLE TRAIT IN A MOUSE MODEL FOR GROWTH HORMONE DEFICIENCY. Osteoporosis International, 21 (1), 289-290. |
Ruffoni, D., Fratzl, P., Lukas, C., Roschger, P., Klaushofer, K., & Weinkamer, R. (2008). Complex transitions in the Bone Mineralization Density Distribution (BMDD) caused by changes in bone turnover. BONE, 42 (1), 64-S64. doi:10.1016/j.bone.2007.12.114 |
Ruffoni, D., Fratzl, P., Roschger, P., Phipps, R., Klaushofer, K., & Weinkamer, R. (2008). Effect of Temporal Changes in Bone Turnover on the Bone Mineralization Density Distribution: A Computer Simulation Study. Journal of Bone and Mineral Research, 23 (12), 1905-1914. doi:10.1359/jbmr.080711 |
Ruffoni, D. (2007). Modeling of material and architectural quality of trabecular bone [Doctoral thesis, Max Planck Institute of Colloids and Interfaces]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/196635 |
Ruffoni, D., Fratzl, P., Roschger, P., Klaushofer, K., & Weinkamer, R. (2007). The bone mineralization density distribution as a fingerprint of the mineralization process. BONE, 40 (5), 1308-1319. doi:10.1016/j.bone.2007.01.012 |
Ruffoni, D., Fratzl, P., Roschger, P., Klaushofer, K., & Weinkamer, R. (2007). Reduction in bone turnover results in a transient highly uniform mineralization state. Calcified Tissue International, 80 (1), 146-S146. |
Soncini, M., Vesentini, S., Ruffoni, D., Orsi, M., Deriu, M. A., & Redaelli, A. (2007). Mechanical response and conformational changes of alpha-actinin domains during unfolding: a molecular dynamics study. Biomechanics and Modeling in Mechanobiology, 6 (6), 399-407. doi:10.1007/s10237-006-0060-z |
Ruffoni, D., Fratzl, P., Roschger, P., Klaushofer, K., & Weinkamer, R. (2006). Modeling the bone mineralization density distribution and its time evolution. BONE, 15. |