Publications and communications of Davide Ruffoni

Pedrinazzi, E., Blouin, S., Pyka, G., Béché, A., Hartmann, M., Simar, A., & Ruffoni, D. (02 July 2024). THE ROLE OF MINERAL HETEROGENEITY AND MATERIAL ANISOTROPY ON TRABECULAR BONE MECHANICS [Paper presentation]. 29th Congress of the European Society of Biomechanics, Edinburgh, United Kingdom.

Malerba, A., Tits, A., Volders, T., Vena, P., & Ruffoni, D. (July 2024). DO STIFFNESS GRADIENTS PLAY A ROLE IN THE PROTECTION OF THE TENDON-TO-BONE INTERFACE? A COMPUTATIONAL STUDY [Poster presentation]. 29th Congress of the European Society of Biomechanics, Edinburgh, United Kingdom.

Gattin, M., Bochud, N., Grossman, Q., Ruffoni, D., Rosi, G., & Naili, S. (15 February 2024). Ultrasound monitoring of multiphase architectured media: Bandgap tracking via the measurement of the reflection coefficient. Applied Acoustics, 217, 109844. doi:10.1016/j.apacoust.2023.109844

Cantamessa, A., Blouin, S., Amini, S., Rummler, M., Berzlanovich, A., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (16 November 2023). Mineralization and Mechanical Insights of Cement Lines in Human Osteonal Bone [Paper presentation]. Annual Benelux meeting of IEEE Engineering in Medicine and Biology Society and 21st National Day of Biomedical Engineering, Bruxelles, Belgium.

Cantamessa, A., Blouin, S., Amini, S., Rummler, M., Berzlanovich, A., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (13 October 2023). A Multimodal Analysis of Cement Lines in Human Osteonal Bone [Poster presentation]. Annual Meeting of the American Society of Bone and Mineral Research, Vancouver, Canada.

Tits, A., Blouin, S., Rummler, M., Kaux, J.-F., Drion, P., van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (August 2023). Structural and functional heterogeneity of mineralized fibrocartilage at the Achilles tendon-bone insertion. Acta Biomaterialia, 166, 409 - 418. doi:10.1016/j.actbio.2023.04.018

Cantamessa, A., Blouin, S., Amini, S., Rummler, M., Berzlanovich, A., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (27 July 2023). Mineral Content and Mechanical Properties of Cement Lines in Human Osteonal Bone [Paper presentation]. European Society of Biomechanics Conference, Maastricht, Netherlands.

Müller, L., Tits, A., Weinkamer, R., Drion, P., Dall'Ara, E., Van Lenthe, G. H., & Ruffoni, D. (10 July 2023). Changes in subchondral bone microstructure and shape with age in tibial knee [Paper presentation]. 28th Congress of the European Society of Biomechanics, Maastricht, Netherlands.

Lew, A. J., Stifler, C. A., Tits, A., Schmidt, C. A., Scholl, A., Cantamessa, A., Müller, L., Delaunois, Y., Compère, P., Ruffoni, D., Buehler, M. J., & Gilbert, P. U. P. A. (July 2023). A Molecular-Scale Understanding of Misorientation Toughening in Corals and Seashells. Advanced Materials, 35 (28), 2300373. doi:10.1002/adma.202300373

Tits, A., Blouin, S., Rummler, M., Kaux, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (31 March 2023). Bone-fibrocartilage crosstalk and osteocyte lacuno-canalicular network at the tendon-bone insertion [Paper presentation]. European Society of Biomechanics Conference, Maastricht, Netherlands.

Delaunois, Y., Tits, A., Grossman, Q., Smeets, S., Malherbe, C., Eppe, G., van Lenthe, G. H., Ruffoni, D.* , & Compère, P.*. (2023). Design Strategies of the Mantis Shrimp Spike: How the Crustacean Cuticle Became a Remarkable Biological Harpoon? Natural Sciences. doi:10.22541/au.167199666.61851387/v1
* These authors have contributed equally to this work.

Saldívar, M. C., Salehi, S., Veeger, R. P. E., Fenu, M., Cantamessa, A., Klimopoulou, M., Talò, G., Moretti, M., Lopa, S., Ruffoni, D., van Osch, G. J. V. M., Fratila-Apachitei, L. E., Doubrovski, E. L., Mirzaali, M. J., & Zadpoor, A. A. (2023). Rational positioning of 3D printed micro-bricks to realize high-fidelity, multi-functional soft-hard interfaces. Cell Reports. Physical Science. doi:10.1101/2023.01.21.525002

Lew, A. J., Stifler, C. A., Cantamessa, A., Tits, A., Ruffoni, D., Gilbert, P. U. P. A., & Buehler, M. J. (2023). Deep learning virtual indenter maps nanoscale hardness rapidly and non-destructively, revealing mechanism and enhancing bioinspired design. Matter, 6 (6), 1975-1991. doi:10.1016/j.matt.2023.03.031

Malerba, A., Tits, A., Volders, T., Vena, P., & Ruffoni, D. (2023). A COMPUTATIONAL INVESTIGATION OF THE TENDON-TO-BONE INSERTION: THE ROLE OF TISSUE ANISOTROPY [Paper presentation]. 28th Congress of the European Society of Biomechanics, Maastricht, Netherlands.

Grossman, Q., Varga, P., & Ruffoni, D. (25 October 2022). Architectured Interfaces in Bimaterial Attachments [Paper presentation]. Workshop of the IRP Coss&Vita, Metamaterials and biomechanics : from bio-inspiration to bio-metamaterials, Arpino, Italy.

Volders, T., Zorzetto, L., Razi, H., Weinkamer, R., & Ruffoni, D. (28 September 2022). Designing Architectured Materials with Tunable Damage Behavior Inspired by Osteonal Bone [Poster presentation]. Imparting Intelligence in and Through Self-Learning Materials and Structures, Ventura, United States - California.

Gattin, M., Bochud, N., Rosi, G., Grossman, Q., Ruffoni, D., & Naili, S. (23 September 2022). Ultrasound characterization of the viscoelastic properties of additively manufactured photopolymer materials. Journal of the Acoustical Society of America, 152 (3), 1901-1912. doi:10.1121/10.0014180

Delaunois, Y., Smeets, S., Tits, A., Ruffoni, D., & Compère, P. (22 September 2022). The spiky exoskeleton of the spearing mantis shrimp; comparative study of 3 puncturing bio-tools [Paper presentation]. Benelux Congress of Zoology, Kortrijk, Belgium.

Volders, T., Zorzetto, L., Razi Hajar, Weinkamer Richard, & Ruffoni, D. (03 August 2022). How to protect a weak spot inside a load-bearing architecture material: a lesson from bone [Paper presentation]. WCCM-APCOM Yokohama 2022, 15th World Congress on Computational Mechanics & 8th Asian Pacific Congress on Computational Mechanics, Yokohama, Japan.

Cantamessa, A., Muraro, P., Delaunois, Y., Compère, P., Blouin, S., Hartmann, M. A., & Ruffoni, D. (27 June 2022). Mineral content and biomechanical properties of fibrolamellar bone [Paper presentation]. European Society of Biomechanics Conference, Porto, Portugal.

Habets, T., Siragusa, F., Müller, A. J., Grossman, Q., Ruffoni, D., Grignard, B., & Detrembleur, C. (07 June 2022). Facile construction of functional poly(monothiocarbonate) copolymers under mild operating conditions. Polymer Chemistry, 13 (21), 3076-3090. doi:10.1039/d2py00307d

De Noni, L., Zorzetto, L., Briatico-Vangosa, F., Rink, M., Ruffoni, D., & Andena, L. (April 2022). Modelling the interphase of 3D printed photo-cured polymers. Composites. Part B, Engineering, 234, 109737. doi:10.1016/j.compositesb.2022.109737

Tits, A., Blouin, S., Rummler, M., KAUX, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (31 March 2022). Biomechanics and mechanobiology of mineralized fibrocartilage at the tendon-bone attachment [Paper presentation]. European Society of Biomechanics Conference, Porto, Portugal.

Tits, A., Blouin, S., Rummler, M., KAUX, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (21 March 2022). Combining high-resolution imaging techniques to reveal the structure and function of fibrocartilage at the tendon-bone insertion [Paper presentation]. International Workshop on Quantitative Musculoskeletal Imaging, in combination with 9th International Symposium on Ultrasonic Characterization of Bone, Noordwijck, Netherlands.

Aghaei, A., Bochud, N., Rosi, G., Grossman, Q., Ruffoni, D., & Naili, S. (March 2022). Ultrasound characterization of bioinspired functionally graded soft-to-hard composites: Experiment and modeling. Journal of the Acoustical Society of America, 151 (3), 1490. doi:10.1121/10.0009630

Müller, L., Tits, A., Plougonven, E., Drion, P., Dall'Ara, E., Léonard, A., Van Lenthe, H., & Ruffoni, D. (2022). Architecture of the trabecular bone between the metaphyseal and subchondral parts in the knee joint [Paper presentation]. 20th National Day of Biomedical Engineering, Bruxelles, Belgium.

Müller, L., Tits, A., Plougonven, E., Drion, P., Dall'Ara, E., Van Lenthe, G. H., & Ruffoni, D. (2022). Differences between subchondral and trabecular bone microporosities beneath the bone-cartilage interface at the knee joint [Poster presentation]. 15th Congress of the International Society of Bone Morphometry, Odense, Denmark.

Grossman, Q., Varga, P., & Ruffoni, D. (29 December 2021). Voxel 3D printing and computer simulations to prototype bimaterial attachments based on local interface patterning [Paper presentation]. 2021 MRS Fall Meeting, Boston, United States - Massachusetts.

Delaunois, Y., Smeets, S., Malherbe, C., Eppe, G., Lecchini, D., Ruffoni, D., & Compère, P. (06 November 2021). Structure and mineralization of the spearing mantis shrimp (Stomatopoda; Lysiosquillina maculata) body and spike cuticles. Journal of Structural Biology, 213 (4). doi:10.1016/j.jsb.2021.107810

Tits, A., Blouin, S., Rummler, M., KAUX, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (02 November 2021). Biomechanical and biological aspects of mineralized fibrocartilage at the tendon-bone interface: a multi-modal analysis [Paper presentation]. Bones and Teeth Gordon Research Conference, Ventura, United States.

Tits, A., Blouin, S., Rummler, M., KAUX, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M. A., & Ruffoni, D. (23 October 2021). A multimodal investigation of mineralized fibrocartilage at the tendon-bone insertion [Paper presentation]. Annual retreat of the Ludwig Boltzmann Institute of Osteology.

Tits, A., Plougonven, E., Blouin, S., Hartmann, M. A., Kaux, J.-F., Drion, P., Fernandez, J., van Lenthe, G. H., & Ruffoni, D. (August 2021). Local anisotropy in mineralized fibrocartilage and subchondral bone beneath the tendon-bone interface. Scientific Reports, 11, 16534. doi:10.1038/s41598-021-95917-4

Tits, A., Blouin, S., KAUX, J.-F., Drion, P., Van Lenthe, G. H., Weinkamer, R., Hartmann, M., & Ruffoni, D. (13 July 2021). Microstructural anisotropy and material gradients in mineralized fibrocartilage at the tendon-bone insertion [Paper presentation]. 26th Congress of the European Society of Biomechanics, Milan (Online), Italy.

Tits, A., & Ruffoni, D. (2021). Joining soft tissues to bone: Insights from modeling and simulations. Bone Reports. doi:10.1016/j.bonr.2020.100742

Tits, A., Varga, P., Volders, T., Kaux, J.-F., Plougonven, E., Fernandez, J., Drion, P., Van Lenthe, G. H., & Ruffoni, D. (October 2020). Local adaptation of bone micro-structure and canal network to tendon insertion investigated by image-based micro-FE simulations. Bone Reports, 13, 100392. doi:10.1016/j.bonr.2020.100393

Tits, A., Varga, P., KAUX, J.-F., Plougonven, E., Fernandez, J., Drion, P., Van Lenthe, G. H., & Ruffoni, D. (24 June 2020). Soft-to-hard biological interfaces: microstructural and micromechanical investigation of the tendon-bone attachment [Paper presentation]. European Calcified Tissue Society Digital Masterclass.

Mirzaali, M. J., Nava, A. H. D. L., Gunashekar, D., Nouri-Goushki, M., Veeger, R. P. E., Grossman, Q., Angeloni, L., Ghatkesar, M. K., Fratila-Apachitei, L. E., Ruffoni, D., Doubrovski, E. L., & Zadpoor, A. A. (2020). Mechanics of bioinspired functionally graded soft-hard composites made by multi-material 3D printing. Composite Structures, 237, 111867. doi:10.1016/j.compstruct.2020.111867

Zorzetto, L., Andena, L., Briatico-Vangosa, F., De Noni, L., Thomassin, J.-M., Jérôme, C., Grossman, Q., Mertens, A., Weinkamer, R., Rink, M., & Ruffoni, D. (2020). Properties and role of interfaces in multimaterial 3D printed composites. Scientific Reports, 10 (1), 22285. doi:10.1038/s41598-020-79230-0

Tits, A., KAUX, J.-F., Plougonven, E., Fernandez, J., Drion, P., Van Lenthe, G. H., & Ruffoni, D. (17 December 2019). Microstructural and micromechanical investigation of the tendon-bone attachment [Paper presentation]. 8th International Conference on Mechanics of Biomaterials and Tissues (ICMOBT), Waikoloa Beach, Hawaii, United States.

Delaunois, Y., Malherbe, C., Tits, A., Ruffoni, D., & Compère, P. (10 September 2019). Reinforcement and adaptation of the mantis shrimp spike: how crustacean cuticle became a perfect harpoon? [Paper presentation]. 15th International Symposium on Biomineralization, Munich, Germany.

Tits, A., KAUX, J.-F., Fernandez, J., Drion, P., Van Lenthe, G. H., & Ruffoni, D. (July 2019). Structural and mechanical analysis of calcaneus bone at the Achilles tendon insertion site [Paper presentation]. 25th World Congress of the European Society of Biomechanics – ESB 2019, Vienne, Austria.

Li, Z., Betts, D., Kuhn, G., Schirmer, M., Müller, R., & Ruffoni, D. (2019). Mechanical regulation of bone formation and resorption around implants in a mouse model of osteopenic bone. Journal of the Royal Society, Interface, 16 (152), 20180667. doi:10.1098/rsif.2018.0667

Zorzetto, L., & Ruffoni, D. (2019). Wood-Inspired 3D-Printed Helical Composites with Tunable and Enhanced Mechanical Performance. Advanced Functional Materials, 29 (1), 1805888. doi:10.1002/adfm.201805888

Ruffoni, D. (12 September 2018). Mechanical Properties of Interfaces in 3D Printed Polymer Composites Investigated by Nanoindentation [Paper presentation]. Indentation 2018, Liege, Belgium.

Ruffoni, D. (28 June 2018). 3D Printing of Bio-inspired Helical Composites with Enhanced Failure Resistance [Paper presentation]. First International Conference on Materials, Mimicking, Manufacturing from and for Bio Application.

Zorzetto, L., & Ruffoni, D. (19 March 2018). Biomechanical role of thin reinforcements layers in helicoidal composites inspired by wood-cells: from field study to transfer to 3D printed composites [Poster presentation]. International School and Conference on Biological Material Science - 4th Euro Bio-inspired Materials 2018, Potsdam, Germany.

Zorzetto, L., & Ruffoni, D. (22 September 2017). Mimicking helicoidal biological materials to improve strength of synthetic composites [Paper presentation]. European Congress and Exhibition on Advanced Materials and Processes 2017 - Euromat2017, Thessaloniki, Greece.

Li, Z., Betts, D., Kuhn, G., Müller, R., & Ruffoni, D. (2017). Mechanical loading therapy increases bone formation while reducing bone resorption following implantation in a mouse model of postmenopausal osteoporosis. JBMR Plus.

Li, Z., Kuhn, G., Schirmer, M., Müller, R., & Ruffoni, D. (2017). Impaired bone formation in ovariectomized mice reduces implant integration as indicated by longitudinal in vivo micro-computed tomography. PLoS ONE, 12 (9), 1-22. doi:10.1371/journal.pone.0184835

Li, Z., Müller, R., & Ruffoni, D. (2017). Bone remodeling and mechanobiology around implants: Insights from small animal imaging. Journal of Orthopaedic Research. doi:10.1002/jor.23758

Ruffoni, D., & van Lenthe, H. (2017). Finite Element Analysis in Bone Research: A Computational Method Relating Structure to Mechanical Function. In Comprehensive Biomaterials II. Elsevier. doi:10.1016/B978-0-12-803581-8.09798-8

Zorzetto, L., Briatico Vangosa, F., Rink, M., Andena, L., & Ruffoni, D. (2017). A multiscale analysis of interface properties in 3D printed composites [Paper presentation]. European Congress and Exhibition on Advanced Materials and Processes.

Zorzetto, L., & Ruffoni, D. (2017). Re-entrant inclusions in cellular solids: From defects to reinforcements. Composite Structures, 176, 195 - 204. doi:10.1016/j.compstruct.2017.05.039

Zorzetto, L., Thomassin, J.-M., Jérôme, C., & Ruffoni, D. (25 October 2016). Mechanical Response of 3D Printed Biomimetic Helical Fiber Composites [Paper presentation]. Engineering Mechanics Institute (EMI) International conference, Metz, France.

Zorzetto, L., Rink, M., Briatico Vangosa, F., Andena, L., & Ruffoni, D. (07 September 2016). Interfaces in multi-material architectures fabricated by polyjet printing [Paper presentation]. 15th European Mechanics of Materials Conference, Brussels, Belgium.

Zorzetto, L., & Ruffoni, D. (07 September 2016). Auxetic inclusions in cellular solids allow tailoring Poisson’s ratio and enhancing stiffness [Paper presentation]. 15th European Mechanics of Materials Conference, Brussels, Belgium.

Li, Z., Betts, D., Kuhn, G., Müller, R., & Ruffoni, D. (28 July 2016). Effect of Mechanical Loading on Peri-Implant Bone Remodeling Measured with Time-Lapsed Imaging and Finite Element Analysis [Paper presentation]. 12th World Congress of Computational Mechanics and 6th Asia-Pacific Congress on Computational Mechanics, Seoul, South Korea.

Li, Z., Betts, D., Kuhn, G., & Ruffoni, D. (July 2016). The mechanical control of peri-implant bone remodeling investigated by in vivo imaging and in silico modeling [Paper presentation]. European Society of Biomechanics (ESB) and the Société de Biomécanique (SB) Congress, Lyon, France.

Zorzetto, L., Thomassin, J.-M., Jérôme, C., & Ruffoni, D. (February 2016). Bioinspired Helicoidal Composites with Tunable Mechanical Behavior by 3-Dimensional Multi-material Printing [Paper presentation]. Gordon Research Conference on Multifunctional Materials and Structures, Ventura, United States.

Zorzetto, L., & Ruffoni, D. (September 2015). Remarkable stiffness enhancement in multilayered honeycombs obtained through periodic variations in Poisson's ratio [Paper presentation]. Euromat2015, Warsaw, Poland.

Collet, M., Bruggi, M., Bauduin, S., Ruffoni, D., & Duysinx, P. (09 July 2015). Simplified fatigue resistance in mechanical engineering using topology optimization [Paper presentation]. 9th European Solid Mechanics Conference, Madrid, Spain.

Ruffoni, D., Christen, P., Scherf, H., & Weinkamer, R. (April 2015). Wolff’s Law and the Interplay between Bone Structure and External Loading. BoneKEy Reports, 13. doi:10.1038/bonekey.2015.40

Li, Z., Kuhn, G., Müller, R., & Ruffoni, D. (2015). Cortical bone response following implantation: changes in bone remodeling and mechanical regulation on periosteal and endosteal surfaces. BoneKEy Reports.

Li, Z., Kuhn, G., von Salis-Soglio, M., Cooke, S. J., Schirmer, M., Mueller, R., & Ruffoni, D. (2015). In vivo monitoring of bone architecture and remodeling after implant insertion: The different responses of cortical and trabecular bone. BONE, 81, 468-477. doi:10.1016/j.bone.2015.08.017

Maurer, M., Weinkamer, R., Müller, R., & Ruffoni, D. (2015). Does mechanical stimulation really protect the architecture of trabecular bone? A simulation study. Biomechanics and Modeling in Mechanobiology. doi:10.1007/s10237-014-0637-x

Zwahlen, A., Christen, D., Ruffoni, D., Schneider, P., Schmoelz, W., & Mueller, R. (2015). Inverse Finite Element Modeling for Characterization of Local Elastic Properties in Image-Guided Failure Assessment of Human Trabecular Bone. Journal of Biomechanical Engineering, 137 (1). doi:10.1115/1.4028991

Li, Z., von Salis Soglio, M., Kuhn, G., Müller, R., & Ruffoni, D. (07 July 2014). The Interplay Between Cortical and Trabecular Bone Following Implant Insertion Investigated by In Vivo Micro-Computed Tomography [Paper presentation]. 7th World Congress of Biomechanics, Boston, United States.

Ruffoni, D., Weinkamer, R., Kuhn, G., & Müller, R. (July 2014). Kinetics of Bone Mineralization and Demineralization in Postmenopausal Osteoporosis [Paper presentation]. 7th World Congress of Biomechanics, Boston, United States.

Bounoure, L., Ruffoni, D., Mueller, R., Kuhn, G. A., Bourgeois, S., Devuyst, O., & Wagner, C. A. (2014). The Role of the Renal Ammonia Transporter Rhcg in Metabolic Responses to Dietary Protein. Journal of the American Society of Nephrology, 25 (9), 2040-2052. doi:10.1681/ASN.2013050466

Donaldson, F., Ruffoni, D., Schneider, P., Alina, L., Zwahlen, A., Pankaj, P., & Mueller, R. (2014). Modeling microdamage behavior of cortical bone. Biomechanics and Modeling in Mechanobiology, 13 (6), 1227-1242. doi:10.1007/s10237-014-0568-6

Zermatten, E., Vetsch, J. R., Ruffoni, D., Hofmann, S., Mueller, R., & Steinfeld, A. (2014). Micro-Computed Tomography Based Computational Fluid Dynamics for the Determination of Shear Stresses in Scaffolds Within a Perfusion Bioreactor. Annals of Biomedical Engineering, 42 (5), 1085-1094. doi:10.1007/s10439-014-0981-0

Li, Z., von Salis-Soglio, M., Cooke, S., Schirmer, M., van Lenthe, H., Müller, R., & Ruffoni, D. (September 2013). Time-lapsed in vivo monitoring of peri-implant bone remodeling in a mouse model [Paper presentation]. International Conference on Computational Bioengineering (ICCB 2013), Leuven, Belgium.

Lambers, F. M., Koch, K., Kuhn, G., Ruffoni, D., Weigt, C., Schulte, F. A., & Mueller, R. (2013). Trabecular bone adapts to long-term cyclic loading by increasing stiffness and normalization of dynamic morphometric rates. BONE, 55 (2), 325-334. doi:10.1016/j.bone.2013.04.016

Lau, K.-H. W., Baylink, D. J., Zhou, X.-D., Rodriguez, D., Bonewald, L. F., Li, Z., Ruffoni, D., Mueller, R., Kesavan, C., & Sheng, M. H.-C. (2013). Osteocyte-derived insulin-like growth factor I is essential for determining bone mechanosensitivity. American Journal of Physiology - Endocrinology and Metabolism, 305 (2), 271-E281. doi:10.1152/ajpendo.00092.2013

Levchuk, A., Sommer, R., Badilatti, S. D., Schulte, F. A., Ruffoni, D., Weigt, C., Kuhn, G., & Mueller, R. (2013). In silico simulations of bone remodeling with improved parameter estimation from local strains and dynamic morphometry in vivo. Journal of Bone and Mineral Research, 28 (1).

Lukas, C., Ruffoni, D., Lambers, F. M., Schulte, F. A., Kuhn, G., Kollmannsberger, P., Weinkamer, R., & Mueller, R. (2013). Mineralization kinetics in murine trabecular bone quantified by time-lapsed in vivo micro-computed tomography. BONE, 56 (1), 55-60. doi:10.1016/j.bone.2013.05.005

Ruffoni, D., Kohler, T., Voide, R., Wirth, A. J., Donahue, L. R., Mueller, R., & van Lenthe, G. H. (2013). High-throughput quantification of the mechanical competence of murine femora - A highly automated approach for large-scale genetic studies. BONE, 55 (1), 216-221. doi:10.1016/j.bone.2013.02.015

Ruffoni, D., Weigt, C., Fattorini, E., Levchuk, A., Schulte, F., Kuhn, G., & Müller, R. (2013). The spatial relationship between bone formation and bone resorption in healthy and ovariectomized mice treated with PTH, bisphosphonate or mechanical loading. Bone (DOI:10.1530/boneabs.1.PP437).

Schulte, F. A., Ruffoni, D., Lambers, F. M., Christen, D., Webster, D. J., Kuhn, G., & Mueller, R. (2013). Local Mechanical Stimuli Regulate Bone Formation and Resorption in Mice at the Tissue Level. PLoS ONE, 8 (4), 62172-12. doi:10.1371/journal.pone.0062172

Schulte, F. A., Zwahlen, A., Lambers, F. M., Kuhn, G., Ruffoni, D., Betts, D., Webster, D. J., & Mueller, R. (2013). Strain-adaptive in silico modeling of bone adaptation - A computer simulation validated by in vivo micro-computed tomography data. BONE, 52 (1), 485-492. doi:10.1016/j.bone.2012.09.008

Zwahlen, A., Christen, D., Ruffoni, D., Schneider, P., Schmoelz, W., & Mueller, R. (2013). Image-guided failure assessment of human trabecular bone - Inverse finite element modelling for characterization of elastic properties. Biomedizinische Technik. Biomedical Engineering, 58 (1). doi:10.1515/bmt-2013-4114

Ruffoni, D., Maurer, M., Weinkamer, R., & Müller, R. (September 2012). The role of disorder in the mechanical control of trabecular bone as a cellular solid structure [Paper presentation]. 6th European Congress on Computational Methods in Applied Sciences and Engineering (ECCOMAS 2012), Vienna, Austria.

Ruffoni, D., Maurer, M., Weinkamer, R., & Müller, R. (July 2012). A beam lattice model to investigate basic aspects of bone remodeling [Paper presentation]. 18th Congress of the European Society of Biomechanics (ESB), Lisbon, Portugal.

Ruffoni, D., Mueller, R., & van Lenthe, G. H. (2012). Mechanisms of reduced implant stability in osteoporotic bone. Biomechanics and Modeling in Mechanobiology, 11 (3-4), 313-323. doi:10.1007/s10237-011-0312-4

Ruffoni, D., Schulte, F. A., Lambers, F. M., Webster, D., Kuhn, G., & Mueller, R. (2012). Experimental quantification of Wolff's law in an in vivo loading model. BONE, 50 (1), 125-S125. doi:10.1016/j.bone.2012.02.387

Ruffoni, D.* , Wirth, A. J.* , Steiner, J. A., Parkinson, I. H., Mueller, R., & van Lenthe, G. H. (2012). The different contributions of cortical and trabecular bone to implant anchorage in a human vertebra. BONE, 50 (3), 733-738. doi:10.1016/j.bone.2011.11.027
* These authors have contributed equally to this work.

Schulte, F. A., Weigt, C., Ruffoni, D., Lambers, F. M., Levchuk, A., Webster, D. J., Kuhn, G., & Mueller, R. (2012). Parathyroid hormone but not bisphosphonate therapy interferes with the local mechanoregulatory mechanism in trabecular bone. BONE, 50 (1), 40-S40. doi:10.1016/j.bone.2012.02.105

Zickler, G. A., Ruffoni, D., Dunlop, J. W. C., Elbaum, R., Weinkamer, R., Fratzl, P., & Antretter, T. (2012). Finite Element Modeling of the Cyclic Wetting Mechanism in the Active Part of Wheat Awns. Biointerphases, 7 (1-4), 42-9. doi:10.1007/s13758-012-0042-x

Lukas, C., Kollmannsberger, P., Ruffoni, D., Roschger, P., Fratzl, P., & Weinkamer, R. (2011). The Heterogeneous Mineral Content of Bone-Using Stochastic Arguments and Simulations to Overcome Experimental Limitations. Journal of Statistical Physics, 144 (2), 316-331. doi:10.1007/s10955-011-0209-8

Lukas, C., Kollmannsberger, P., Ruffoni, D., Roschger, P., Fratzl, P., & Weinkamer, R. (2011). The effect of a disturbed mineralization process on the bone mineralization density distribution (BMDD). BONE, 48 (2), 181-S182. doi:10.1016/j.bone.2011.03.422

Lukas, C., Lambers, F., Ruffoni, D., Schulte, F. A., Kuhn, G. A., Kollmannsberger, P., Weinkamer, R., & Mueller, R. (2011). Quantification of the interplay between mineralization and remodeling in trabecular bone assessed by in vivo micro-computed tomography. BONE, 48 (2), 205-S205. doi:10.1016/j.bone.2011.03.467

Ruffoni, D., Steiner, J., Wirth, A., Mueller, T., Goldhahn, J., Müller, R., & van Lenthe, H. (January 2011). How does cement augmentation increase the mechanical properties of trabecular bone? [Paper presentation]. 57th Annual Meeting of the Orthopaedic Research Society, Long beach, United States.

Ruffoni, D., & van Lenthe, H. (2011). Finite element analysis in bone research: a computational method relating structure to mechanical function. In Comprehensive Biomaterials. Elsevier.

Kallai, I.* , van Lenthe, G. H.* , Ruffoni, D., Zilberman, Y., Muller, R., Pelled, G., & Gazit, D. (2010). Quantitative, structural, and image-based mechanical analysis of nonunion fracture repaired by genetically engineered mesenchymal stem cells. Journal of Biomechanics, 43 (12), 2315-2320. doi:10.1016/j.jbiomech.2010.04.031
* These authors have contributed equally to this work.

Mader, K., Schneider, P., Ruffoni, D., van Lenthe, G. H., Thiran, J.-P., Mueller, R., & Stampanoni, M. (2010). Automated, High-Throughput, Multi-scale Assessment of Bone Morphology and Bone Competence. IFMBE Proceedings, 31, 841-843. doi:10.1007/978-3-642-14515-5_214

Ruffoni, D., Dunlop, J. W. C., Fratzl, P., & Weinkamer, R. (2010). Effect of minimal defects in periodic cellular solids. Philosophical Magazine, 90 (13), 1807-1818. doi:10.1080/14786430903571404

Ruffoni, D., Voide, R., Kohler, T., Donahue, L. R., Mueller, R., & van Lenthe, G. H. (2010). BONE MECHANICAL COMPETENCE IS A HIGHLY HERITABLE TRAIT IN A MOUSE MODEL FOR GROWTH HORMONE DEFICIENCY. Osteoporosis International, 21 (1), 289-290.

Ruffoni, D., Fratzl, P., Lukas, C., Roschger, P., Klaushofer, K., & Weinkamer, R. (2008). Complex transitions in the Bone Mineralization Density Distribution (BMDD) caused by changes in bone turnover. BONE, 42 (1), 64-S64. doi:10.1016/j.bone.2007.12.114

Ruffoni, D., Fratzl, P., Roschger, P., Phipps, R., Klaushofer, K., & Weinkamer, R. (2008). Effect of Temporal Changes in Bone Turnover on the Bone Mineralization Density Distribution: A Computer Simulation Study. Journal of Bone and Mineral Research, 23 (12), 1905-1914. doi:10.1359/jbmr.080711

Ruffoni, D. (2007). Modeling of material and architectural quality of trabecular bone [Doctoral thesis, Max Planck Institute of Colloids and Interfaces]. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/196635

Ruffoni, D., Fratzl, P., Roschger, P., Klaushofer, K., & Weinkamer, R. (2007). The bone mineralization density distribution as a fingerprint of the mineralization process. BONE, 40 (5), 1308-1319. doi:10.1016/j.bone.2007.01.012

Ruffoni, D., Fratzl, P., Roschger, P., Klaushofer, K., & Weinkamer, R. (2007). Reduction in bone turnover results in a transient highly uniform mineralization state. Calcified Tissue International, 80 (1), 146-S146.

Soncini, M., Vesentini, S., Ruffoni, D., Orsi, M., Deriu, M. A., & Redaelli, A. (2007). Mechanical response and conformational changes of alpha-actinin domains during unfolding: a molecular dynamics study. Biomechanics and Modeling in Mechanobiology, 6 (6), 399-407. doi:10.1007/s10237-006-0060-z

Ruffoni, D., Fratzl, P., Roschger, P., Klaushofer, K., & Weinkamer, R. (2006). Modeling the bone mineralization density distribution and its time evolution. BONE, 15.