Publications and communications of Gilles Darcis

Fombellida-Lopez, C., Östling Ellen, Aguilar Ortmans, D., DELLOT, P., MARECHAL, N., Vanwinge, C., Ladang, A., Cavalier, E., SUSIN, F., VAIRA, D., Hayette, M.-P., Reenaers, C., Moutschen, M., Pasternak O. Alexander, & Darcis, G. (23 September 2024). Impact of ART simplification with dolutegravir and lamivudine on the HIV reservoir [Poster presentation]. HIV Cure Symposium 2024, Gand, Belgium.

Buanec, H. L., Schiavon, V., Merandet, M., How-Kit, A., Bergerat, D., Fombellida-Lopez, C., Bensussan, A., Bouaziz, J.-D., Burny, A., Darcis, G., Song, H., Sajadi, M. M., Kottilil, S., Gallo, R. C., & Zagury, D. (19 March 2024). Early elevated IFNα is a key mediator of HIV pathogenesis. Communications Medicine, 4 (1), 53. doi:10.1038/s43856-024-00454-6

Le Buanec, H., Schiavon, V., Merandet, M., How-Kit, A., Song, H., Bergerat, D., Fombellida-Lopez, C., Bensussan, A., Bouaziz, J.-D., Burny, A., Darcis, G., Sajadi, M. M., Kottilil, S., Zagury, D., & Gallo, R. C. (19 March 2024). IFNα induces CCR5 in CD4+ T cells of HIV patients causing pathogenic elevation. Communications Medicine, 4 (1), 52. doi:10.1038/s43856-024-00453-7

Scaia, D., Fombellida, K., Maes, N., El Moussaoui, M., & Darcis, G. (14 March 2024). Risk Factors for Late HIV Presentation in Patients Treated at a Single Belgian Reference Centre from 2018 to 2022. Infectious Disease Reports, 16 (2), 239 - 248. doi:10.3390/idr16020019

Fombellida-Lopez, C., Berkhout, B., Darcis, G., & Pasternak, A. O. (2024). Persistent HIV-1 transcription during ART: time to reassess its significance? Current Opinion in HIV and AIDS. doi:10.1097/COH.0000000000000849

El Moussaoui, M., Bontems, S., Meex, C., Hayette, M.-P., LEJEUNE, M., Hong, S. L., Dellicour, S., Moutschen, M., CAMBISANO, N., Renotte, N., Bours, V., Darcis, G., Artesi, M.* , & Durkin, K.*. (2024). Intrahost evolution leading to distinct lineages in the upper and lower respiratory tracts during SARS-CoV-2 prolonged infection. medRxiv preprint. doi:10.1101/2024.03.03.24303157

Laverdeur, J., Desmecht, D., Hayette, M.-P., & Darcis, G. (15 January 2024). Dengue and chikungunya: future threats for Northern Europe? Frontiers in Epidemiology, 4. doi:10.3389/fepid.2024.1342723

Diep, A. N.* , Schyns, J.* , Gourzonès, C.* , Goffin, E., Papadopoulos, I., Moges, S., MINNER, F., Ek, O., Bonhomme, G., Paridans, M., Gillain, N., Husson, E., Garigliany, M.-M., Darcis, G., Saegerman, C., Desmecht, D., Guillaume, M.* , Donneau, A.-F.* , Bureau, F.* , & Gillet, L.*. (2023). How do successive vaccinations and SARS-CoV-2 infections impact humoral immunity dynamics: an 18-month longitudinal study [letter to the editor]. Journal of Infection. doi:10.1016/j.jinf.2023.11.006

Callewaert, C., Pezavant, M., Vandaele, R., Meeus, B., Vankrunkelsven, E., Van Goethem, P., Plumacker, A., Misset, B., Darcis, G., PIRET, S., De Vleeschouwer, L., Staelens, F., Van Varenbergh, K., Tombeur, S., Ottevaere, A., Montag, I., Vandecandelaere, P., Jonckheere, S., Vandekerckhove, L., ... Guyot, H. (19 September 2023). Sniffing out safety: canine detection and identification of SARS-CoV-2 infection from armpit sweat. Frontiers in Medicine, 10. doi:10.3389/fmed.2023.1185779

Fombellida-Lopez, C., Pasternak, A. O., Cicilionyté, A., Maes, N., Vanwinge, C., Ormenese, S., Ladang, A., Cavalier, E., Winchester, L., Fletcher, C., SUSIN, F., VAIRA, D., Hayette, M.-P., Reenaers, C., Moutschen, M., & Darcis, G. (11 September 2023). Doubling dolutegravir dosage reduces HIV persistence markers in ART-treated adults [Poster presentation]. HIV Cure Symposium 2023, Gand, Belgium.

Vossius, G., Meex, C., Moerman, F., THYS, M., Ernst, M., Bourgeois, M.-E., Wagner, L., DELAHAYE, T., & Darcis, G. (11 September 2023). Clinical Outcomes of Third-Generation Cephalosporin Definitive Therapy for Bloodstream Infections Due to Enterobacterales with Potential AmpC Induction: A Single-Center Retrospective Study. Pathogens (Basel, Switzerland), 12 (9), 1152. doi:10.3390/pathogens12091152

COVID-19 Host Genetics Initiative, Rahmouni, S., Georges, M., Moutschen, M., Darcis, G., & Beguin, Y. (September 2023). A second update on mapping the human genetic architecture of COVID-19. Nature, 621 (7977), 7 - E26. doi:10.1038/s41586-023-06355-3

Llucià-Carol, L., Elena Muiño, Natalia Cullell, Jara Cárcel-Márquez, Miquel Lledós, Cristina Gallego-Fabrega, Jesús Martin-Campos, Joan Martí-Fàbregas, Ana Aguilera-Simón, Anna M. Planas, Marta L. DeDiego, Alicia de Felipe Mimbrera, Jaime Masjuan, Sebastián García-Madrona, Tomás Segura, Esther González-Villar, Gemma Serrano-Heras, Ana Domínguez Mayoral, Paloma Menéndez-Valladares, ... Israel Fernández-Cadenas. (30 August 2023). Genetic Architecture of Ischaemic Strokes after COVID-19 Shows Similarities with Large Vessel Strokes. International Journal of Molecular Sciences, 24 (17). doi:10.3390/ijms241713452

Lambert, N., El Moussaoui, M., Baron, F., Maquet, P., & Darcis, G. (06 July 2023). Virus-Specific T-Cell Therapy for Viral Infections of the Central Nervous System: A Review. Viruses, 15 (7), 1510. doi:10.3390/v15071510

Kremer, C., Torneri, A., Libin, P. J. K., Meex, C., Hayette, M.-P., Bontems, S., Durkin, K. W., Artesi, M., Bours, V., Lemey, P., Darcis, G., Hens, N., & Meuris, C. (16 June 2023). Reconstruction of SARS-CoV-2 outbreaks in a primary school using epidemiological and genomic data. Epidemics, 44, 100701. doi:10.1016/j.epidem.2023.100701

Le Buanec, H., Schiavon, V., Merandet, M., How-Kit, A., Bergerat, D., Fombellida-Lopez, C., Bensussan, A., Bouaziz, J.-D., Burny, A., Darcis, G., Song, H., Sajadi, M. M., Kottilil, S., Gallo, R. C., & Zagury, D. (2023). Early Elevated IFNα Identified as the Key Mediator of HIV Pathogenesis and its low level a Hallmark of Elite Controllers. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/308341. doi:10.21203/rs.3.rs-2813601/v1

Le Buanec, H., Schiavon, V., Merandet, M., How-Kit, A., Song, H., Bergerat, D., Fombellida-Lopez, C., Bensussan, A., Bouaziz, J.-D., Burny, A., Darcis, G., Sajadi, M. M., Kottilil, S., Zagury, D., & Gallo, R. C. (2023). IFNα induces CCR5 in CD4+ T-cells, causing its anti- HIV inefficiency and its subsequent pathogenic elevation, partially controlled by anti-HIV therapy. ORBi-University of Liège. https://orbi.uliege.be/handle/2268/308342. doi:10.21203/rs.3.rs-2813616/v1

El Moussaoui, M., Guiot, J., FRIPPIAT, F., & Darcis, G. (May 2023). Une cause émergente de fatigue et de douleurs chroniques : l’affection post-COVID-19 ou COVID long. Revue Médicale de Liège, 78 (5-6), 299 - 304.

Nasreddine, R., Florence, E., Yombi, J. C., Henrard, S., Darcis, G., Van Praet, J., Vandekerckhove, L., Allard, S. D., Demeester, R., Messiaen, P., Ausselet, N., Delforge, M., De Wit, S., & Belgian Research on AIDS and HIV Consortium (BREACH). (2023). Efficacy, durability, and tolerability of bictegravir/emtricitabine/tenofovir alafenamide for the treatment of HIV in a real-world setting in Belgium. HIV Medicine. doi:10.1111/hiv.13493

de Crane D'Heysselaer, S., Parisi, G., Lisson, M., Bruyère, O., Donneau, A.-F., Fontaine, S., Gillet, L., Bureau, F., Darcis, G., Thiry, E., Ducatez, M., Snoeck, C. J., Zientara, S., Haddad, N., Humblet, M.-F., Ludwig-Begall, L., Daube, G., Thiry, D., Misset, B., ... Haubruge, E. (27 February 2023). Systematic Review of the Key Factors Influencing the Indoor Airborne Spread of SARS-CoV-2. Pathogens, 12 (3), 382. doi:10.3390/pathogens12030382

Fombellida-Lopez, C., Pasternak, A. O., Cicilionyté, A., Maes, N., Vanwinge, C., Ormenese, S., Ladang, A., Cavalier, E., Winchester, L., Fletcher, C., SUSIN, F., VAIRA, D., Hayette, M.-P., Reenaers, C., Moutschen, M., & Darcis, G. (21 February 2023). Doubling dolutegravir dosage reduces HIV persistence markers in ART-treated adults [Poster presentation]. Conference on Retroviruses and Opportunistic Infection (CROI 2023), Seattle, United States.

Meuris, C., Darcis, G., Orban, C., Hayette, M.-P., Meex, C., Desmecht, D., & Bours, V. (2023). Study of asymptomatic rectal carriage of Monkeypox virus in men who have sex with men, and immunological answer to vaccination, followed in Liège University Hospital. https://orbi.uliege.be/handle/2268/298473

El Moussaoui, M., Desmecht, S., Lambert, N., Maes, N., Braghini, J., MARECHAL, N., Quintana, C., BRIQUET, K., Gofflot, S., Toussaint, F., Hayette, M.-P., Vermeersch, P., Lutteri, L., GREGOIRE, C., Beguin, Y., Rahmouni, S., Moutschen, M., Desmecht, D., & Darcis, G. (2023). Cluster Analysis Identifies Distinct Patterns of T-Cell and Humoral Immune Responses Evolution Following a Third Dose of SARS-CoV-2 Vaccine in People Living with HIV. Viruses, 15, 1435. doi:10.3390/v15071435

Mayasi Ngongo, N., Kamangu Ntambwe, E., Situakibanza Nani-Tuma, H., Mbula Mambimbi, M., Mandina Ndona, M., Longokolo Mashi, M., Bepouka Izizag, B., Lukiana, T., Odio Ossam, J., Mangala Sonzi, D., Maes, N., Moutschen, M., El Moussaoui, M., & Darcis, G. (2023). Human Immunodeficiency Virus Viral Load Monitoring and Rate of Virologic Suppression Among Patients Receiving Antiretroviral Therapy in Democratic Republic of the Congo, 2013-2020. Open Forum Infectious Diseases, 10 (6), 2-7. doi:10.1093/ofid/ofad242

Fombellida-Lopez, C., Pasternak, A. O., Cicilionyté, A., Maes, N., Vanwinge, C., Ormenese, S., Ladang, A., Cavalier, E., Winchester, L., Fletcher, C., SUSIN, F., VAIRA, D., Hayette, M.-P., Reenaers, C., Moutschen, M., & Darcis, G. (23 November 2022). Doubling dolutegravir dosage reduces HIV persistence markers in ART-treated adults [Poster presentation]. Belgium Research on AIDS and HIV Consortium (BREACH 2022), Bruxelles, Belgium.

Paridans, M., Monseur, J., Donneau, A.-F., Gillain, N., Husson, E., Leclercq, D., Meuris, C., Darcis, G., Moutschen, M., Saegerman, C., Gillet, L., Bureau, F., Guillaume, M., & Pétré, B. (2022). The Dynamic Relationship between the Intention and Final Decision for the COVID-19 Booster: A Study among Students and Staff at the University of Liège, Belgium. Vaccines. doi:10.3390/vaccines10091485

El Moussaoui, M., Desmecht, S., Tashkeev, A., Lambert, N., Maes, N., Braghini, J., MARECHAL, N., Quintana, C., BRIQUET, K., Gofflot, S., TOUSSAINT, F., Hayette, M.-P., Vermeersch, P., Lutteri, L., Grégoire, C., Beguin, Y., Rahmouni, S., Moutschen, M., Desmecht, D., & Darcis, G. (05 September 2022). Reduced T-cell response following a third dose of SARS-CoV-2 vaccine in infection-naïve people living with HIV. Journal of Infection, 85, 751-755. doi:10.1016/j.jinf.2022.09.006

El Moussaoui, M., Maes, N., Fombellida, K., VAIRA, D., Moutschen, M., & Darcis, G. (02 September 2022). Impact de la pandémie de Covid-19 sur les soins de santé des personnes vivant avec le VIH à Liège, Belgique [Paper presentation]. Congrès annuel de l'Association Latine pour l'Analyse des Systèmes de Santé (CALASS), Barcelone, Spain.

Pathak, G. A., Karjalainen, J., Stevens, C., Neale, B. M., Daly, M., Ganna, A., Andrews, S. J., Kanai, M., Cordioli, M., Polimanti, R., Harerimana, N., Pirinen, M., Liao, R. G., Chwialkowska, K., Trankiem, A., Balaconis, M. K., Nguyen, H., Solomonson, M., Veerapen, K., ... Baillie, J. K. (03 August 2022). A first update on mapping the human genetic architecture of COVID-19. Nature, 608, 1-E10. doi:10.1038/s41586-022-04826-7

Cruz, R., Almeida, S. D.-D., Heredia, M. L., Quintela, I., Ceballos, F. C., Pita, G., Lorenzo-Salazar, J. M., González-Montelongo, R., Gago-Domínguez, M., Porras, M. S., Castaño, J. A. T., Nevado, J., Aguado, J. M., Aguilar, C., Aguilera-Albesa, S., Almadana, V., Almoguera, B., Alvarez, N., Andreu-Bernabeu, Á., ... Carracedo, Á. (2022). Novel genes and sex differences in COVID-19 severity. Human Molecular Genetics. doi:10.1093/hmg/ddac132

El Moussaoui, M., Maes, N., Hong, S. L., Lambert, N., Gofflot, S., DELLOT, P., Belhadj, Y., Huynen, P., Hayette, M.-P., Meex, C., Bontems, S., Defêche, J., Godderis, L., Molenberghs, G., Meuris, C., Artesi, M., Durkin, K., Rahmouni, S., GREGOIRE, C., ... DARCIS, G. (14 June 2022). Evaluation of Screening Program and Phylogenetic Analysis of SARS-CoV-2 Infections among Hospital Healthcare Workers in Liège, Belgium. Viruses, 14 (6), 1302. doi:10.3390/v14061302

Mayasi, N., Situakibanza, H., Mbula, M., Longokolo, M., Maes, N., Bepouka, B., Ossam, J. O., MOUTSCHEN, M., & DARCIS, G. (11 March 2022). Retention in care and predictors of attrition among HIV-infected patients who started antiretroviral therapy in Kinshasa, DRC, before and after the implementation of the ‘treat-all’ strategy. PLOS Global Public Health, 2 (3), 0000259. doi:10.1371/journal.pgph.0000259

Kousathanas, A., Pairo-Castineira, E., Rawlik, K., Stuckey, A., Odhams, C. A., Walker, S., Russell, C. D., Malinauskas, T., Wu, Y., Millar, J., Shen, X., Elliott, K. S., Griffiths, F., Oosthuyzen, W., Morrice, K., Keating, S., Wang, B., Rhodes, D., Klaric, L., ... LAMBERMONT, B. (Other coll.). (2022). Whole-genome sequencing reveals host factors underlying critical COVID-19. Nature. doi:10.1038/s41586-022-04576-6

Cambier, M., Henket, M., Frix, A.-N., Gofflot, S., THYS, M., Tomasetti, S., Peired, A., Struman, I., Rousseau, A.-F., Misset, B., Darcis, G., Moutschen, M., Louis, R., Njock, M.-S., Cavalier, E., & Guiot, J. (2022). Increased KL-6 levels in moderate to severe COVID-19 infection. PLoS ONE, 17 (11), 0273107. doi:10.1371/journal.pone.0273107

Desmecht, S.* , Tashkeev, A.* , El Moussaoui, M., MARECHAL, N., Perée, H., Tokunaga, Y., Fombellida-Lopez, C., Polese, B., Legrand, C., Wéry, M., Mni, M., Fouillien, N., TOUSSAINT, F., Gillet, L., Bureau, F., LUTTERI, L., HAYETTE, M.-P., MOUTSCHEN, M., MEURIS, C., ... DARCIS, G.*. (2022). Kinetics and persistence of the cellular and humoral immune responses to BNT162b2 mRNA vaccine in SARS-CoV-2-naive and -experienced subjects: impact of booster dose and breakthrough infections. Frontiers in Immunology, 13, 863554. doi:10.3389/fimmu.2022.863554

Donneau, A.-F.* , Guillaume, M.* , BOURS, V., Dandoy, M., DARCIS, G., Desmecht, D., Diep, A. N., Fievez, L., Garigliany, M.-M., Gillain, N., Husson, E., Michel, F., MOUTSCHEN, M., Paridans, M., Pétré, B., Sabatel, C., Saegerman, C., Tytgat, A., Gillet, L.* , & Bureau, F.*. (2022). University population-based prospective cohort study of SARS-CoV- 2 infection and immunity (SARSSURV-ULiège): a study protocol. BMJ Open. doi:10.1136/bmjopen-2021-055721

Van Beckhoven, D., Serrien, B., Montourcy, M., Verhofstede, C., Van den Bossche, D., Libois, A., De Geyter, D., Martin, T., Van den Eynde, S., Vuylsteke, B., Darcis, G., van Halem, K., Florence, E., Deblonde, J., Ausselet, N. (Other coll.), Delforge, M.-L. (Other coll.), Demeester, R. (Other coll.), De Munter, P. (Other coll.), Goffard, J.-C. (Other coll.), ... Yombi, J.-C. (Other coll.). (2022). Impact of COVID-19 on the Belgian HIV epidemic: slowdown of HIV transmission and testing and adaptation of care. BMC Infectious Diseases, 22 (1), 901. doi:10.1186/s12879-022-07879-1

El Moussaoui, M., Lambert, N., MAES, N., Fombellida, K., VAIRA, D., MOUTSCHEN, M., & DARCIS, G. (30 November 2021). Impact of the COVID-19 pandemic situation on HIV care in Liège, Belgium [Poster presentation]. BREACH Symposium 2021, Bruxelles, Belgium.

Nakanishi, T., Pigazzini, S., Degenhardt, F., Cordioli, M., Butler-Laporte, G., Maya-Miles, D., Nafría-Jiménez, B., Bouysran, Y., Niemi, M., Palom, A., Ellinghaus, D., Khan, A., Martínez-Bueno, M., Rolker, S., Amitano, S., Tato, L. R., Fava, F., Spinner, C. D., Prati, D., ... consortium, C.-H. (October 2021). Age-dependent impact of the major common genetic risk factor for COVID-19 on severity and mortality. Journal of Clinical Investigation, Online ahead of print.. doi:10.1172/JCI152386

El Moussaoui, M., Lambert, N., MAES, N., Fombellida, K., VAIRA, D., MOUTSCHEN, M., & DARCIS, G. (2021). Impact of the COVID-19 pandemic situation on HIV care in Liège, Belgium. HIV Research & Clinical Practice. doi:10.1080/25787489.2021.1948773

BOUQUEGNEAU, A., HUART, J., LUTTERI, L., ERPICUM, P., GROSCH, S., Résimont, G., WIESEN, P., ROUSSEAU, A.-F., BOVY, C., KRZESINSKI, J.-M., THYS, M., LAMBERMONT, B., Misset, B., Pottel, H., DARCIS, G., CAVALIER, E., JOURET, F., & DELANAYE, P. (2021). Survivors of COVID-19 mostly recover from tubular proteinuria and acute kidney injury after hospital discharge. Journal of Nephrology, 34 (4), 967-969. doi:10.1007/s40620-021-01075-1

Darcis, G., Bouquegneau, A., Maes, N., Thys, M., Henket, M., Labye, F., Rousseau, A.-F., Canivet, P., Desir, C., Calmes, D., Schils, R., De Worm, S., Léonard, P., Meunier, P., Moutschen, M., Louis, R., & Guiot, J. (2021). Long-term clinical follow-up of patients suffering from moderate-to-severe COVID-19 infection: a monocentric prospective observational cohort study. International Journal of Infectious Diseases, 109, 209-216. doi:10.1016/j.ijid.2021.07.016

Defêche, J., AZARZAR, S., Mesdagh, A., DELLOT, P., Tytgat, A., Bureau, F., Gillet, L., Belhadj, Y., BONTEMS, S., HAYETTE, M.-P., Schils, R., Rahmouni, S., ERNST, M., MOUTSCHEN, M., & DARCIS, G. (2021). In-Depth Longitudinal Comparison of Clinical Specimens to Detect SARS-CoV-2. Pathogens (Basel, Switzerland), 10 (11). doi:10.3390/pathogens10111362

Gregoire, E., Pirotte, B. F., Moerman, F., Altdorfer, A., Gaspard, L., Firre, E., Moonen, M., Fraipont, V., ERNST, M., & DARCIS, G. (2021). Incidence and Risk Factors of COVID-19-Associated Pulmonary Aspergillosis in Intensive Care Unit-A Monocentric Retrospective Observational Study. Pathogens (Basel, Switzerland), 10 (11). doi:10.3390/pathogens10111370

Meuris, C., Kremer, C., Geerinck, A., Locquet, M., Bruyère, O., Defêche, J., Meex, C., Hayette, M.-P., Duchene, L., Dellot, P., Azarzar, S., Maréchal, N., Sauvage, A.-S., Frippiat, F., Giot, J.-B., Léonard, P., Fombellida, K., Moutschen, M., Durkin, K., ... Darcis, G. (2021). Transmission of SARS-CoV-2 After COVID-19 Screening and Mitigation Measures for Primary School Children Attending School in Liège, Belgium. JAMA Network Open, 4 (10), 2128757. doi:10.1001/jamanetworkopen.2021.28757

Ngongo, N. M., Darcis, G., Nanituna, H. S., Mambimbi, M. M., Maes, N., Mashi, M. L., Bepouka Izizag, B., Moutschen, M., & Lepira Bompeka, F. (2021). Longitudinal analysis of sociodemographic, clinical and therapeutic factors of HIV-infected individuals in Kinshasa at antiretroviral therapy initiation during 2006-2017. PLoS ONE, 16 (11), 0259073. doi:10.1371/journal.pone.0259073

Ngongo, N. M., Nani-Tuma, H. S., Mambimbi, M. M., Mashi, M. L., Izizag, B. B., Maes, N., Moutschen, M., & Darcis, G. (2021). Progressive phasing out of baseline CD4+ cell count testing for people living with HIV in Kinshasa, Democratic Republic of the Congo. AIDS (London, England), 35 (5), 841-843. doi:10.1097/QAD.0000000000002802

Ngongo, N. M., Nani-Tuma, H. S., Mambimbi, M. M., Mashi, M. L., Izizag, B. B., Ndolumingu, F. K., Maes, N., Moutschen, M., & Darcis, G. (2021). Decrease in late presentation for HIV care in Kinshasa, DRC, 2006-2020. AIDS Research and Therapy, 18 (1), 41. doi:10.1186/s12981-021-00366-8

Niemi, M., Gazon, H., JUSZCZAK, D., FADEUR, M., CAMBY, S., MEURIS, C., THYS, M., JACQUES, J., HENKET, M., BEGUIN, Y., Rahmouni, S., Lebrun, M., MOUTSCHEN, M., Misset, B., DARCIS, G., GUIOT, J., AZARZAR, S., DELLOT, P., GOFFLOT, S., ... HUYNEN, P. (Other coll.). (2021). Mapping the human genetic architecture of COVID-19. Nature, 600, 472-477. doi:10.1038/s41586-021-03767-x

Plum, P.-E., Darcis, G., & Moutschen, M. (2021). L’arrivée des bithérapies dans le traitement du virus de l’immunodéficience humaine : la fin d’un dogme? Revue Médicale de Liège, 76 (9), 677 - 682.

Plum, P.-E., Maes, N., Sauvage, A.-S., Frippiat, F., Meuris, C., Uurlings, F., Lecomte, M., Léonard, P., Paquot, N., Fombellida, K., Vaira, D., Moutschen, M., & Darcis, G. (2021). Impact of switch from tenofovir disoproxil fumarate-based regimens to tenofovir alafenamide-based regimens on lipid profile, weight gain and cardiovascular risk score in people living with HIV. BMC Infectious Diseases, 21 (1), 910. doi:10.1186/s12879-021-06479-9

Chaslain, A., Fombellida-Lopez, C., SUSIN, F., VAIRA, D., Moutschen, M., & Darcis, G. (September 2020). Obstacles à la guérison de l'infection par le VIH. Partie 2 : la réplication continue malgré le traitement. Revue Médicale de Liège, 75 (9), 582-587.

Fombellida-Lopez, C., Chaslain, A., SUSIN, F., VAIRA, D., Moutschen, M., & DARCIS, G. (September 2020). Obstacles à la guérison de l'infection par le VIH. Partie 1 : les réservoirs latents. Revue Médicale de Liège, 75 (9), 573-577.

Ait-Ammar, A., Kula, A., DARCIS, G., Verdikt, R., De wit, S., Gautier, V., Mallon, P., Marcello, A., Rohr, O., & Van Lint, C. (2020). Current Status of Latency Reversing Agents Facing the Heterogeneity of HIV-1 Cellular and Tissue Reservoirs. Frontiers in Microbiology. doi:10.3389/fmicb.2019.03060

Darcis, G., Berkhout, B., & Pasternak, A. O. (2020). Differences in HIV Markers between Infected Individuals Treated with Different ART Regimens: Implications for the Persistence of Viral Reservoirs. Viruses, 12 (5). doi:10.3390/v12050489

Darcis, G., Kootstra, N. A., Hooibrink, B., van Montfort, T., Maurer, I., Groen, K., Jurriaans, S., Bakker, M., van Lint, C., Berkhout, B., & Pasternak, A. O. (2020). CD32+CD4+ T Cells Are Highly Enriched for HIV DNA and Can Support Transcriptional Latency. Cell Reports, 30 (7), 2284-2296.e3. doi:10.1016/j.celrep.2020.01.071

DARCIS, G., VAIRA, D., & MOUTSCHEN, M. (2020). Impact of coronavirus pandemic and containment measures on HIV diagnosis. Epidemiology and Infection. doi:10.1017/S0950268820001867

El Moussaoui, M., Lambert, I., MAES, N., SAUVAGE, A.-S., FRIPPIAT, F., MEURIS, C., UURLINGS, F., LECOMTE, M., LEONARD, P., Fombellida, K., VAIRA, D., Vercheval, C., Moutschen, M., & Darcis, G. (2020). Evolution of Drug Interactions With Antiretroviral Medication in People With HIV. Open Forum Infectious Diseases, 7 (11), 416. doi:10.1093/ofid/ofaa416

Ilbert, C., SABATIELLO, M., KURTH, W., Longrée, L., MOUTSCHEN, M., & DARCIS, G. (2020). Le syndrome de Schnitzler. Revue Médicale de Liège.

El Moussaoui, M., Lambert, I., MAES, N., SAUVAGE, A.-S., FRIPPIAT, F., MEURIS, C., UURLINGS, F., LECOMTE, M., LEONARD, P., FOMBELLIDA, K., VAIRA, D., Vercheval, C., MOUTSCHEN, M., & DARCIS, G. (22 November 2019). Evolution of drug interactions with antiretroviral medications in HIV-infected patients [Poster presentation]. 8th BREACH SYMPOSIUM, Liège, Belgium.

El Moussaoui, M., Lambert, I., MAES, N., SAUVAGE, A.-S., FRIPPIAT, F., MEURIS, C., UURLINGS, F., LECOMTE, M., LEONARD, P., Fombellida, K., VAIRA, D., Vercheval, C., MOUTSCHEN, M., & DARCIS, G. (08 November 2019). Evolution of drug interactions with antiretroviral medications in HIV-infected patients [Paper presentation]. 17th European AIDS Conference, Bâle, Switzerland.

Verdikt, R., DARCIS, G., Ait-Ammar, A., & Van Lint, C. (2019). Applications of CRISPR/Cas9 tools in deciphering the mechanisms of HIV-1 persistence. Current Opinion in Virology. doi:10.1016/j.coviro.2019.07.004

Cimpaye, O., Louis, R., Darcis, G., Beaudart, C., & MEURIS, C. (2019). Evaluation de l'application des recommandations du Conseil Supérieur de la Santé relatives à l'isolement respiratoire des malades atteints de la tuberculose pulmonaire au CHU de Liège. Revue Médicale de Liège, 74 (9), 465-470.

DARCIS, G., Berkhout, B., & Pasternak, A. (2019). The Quest for Cellular Markers of HIV Reservoirs: Any Color You Like. Frontiers in Immunology. doi:10.3389/fimmu.2019.02251

DARCIS, G., Binda, C., Klaver, B., Herrera-Carrillo, E., Berkhout, B., & Das, A. (2019). The Impact of HIV-1 Genetic Diversity on CRISPR-Cas9 Antiviral Activity and Viral Escape. Viruses. doi:10.3390/v11030255

DARCIS, G., MAES, N., Pasternak, A., SAUVAGE, A.-S., FRIPPIAT, F., MEURIS, C., UURLINGS, F., LECOMTE, M., LEONARD, P., El Moussaoui, M., Fombellida, K., VAIRA, D.* , & MOUTSCHEN, M.*. (2019). Detectability of HIV residual Viremia despite therapy is highly associated with treatment with a protease inhibitor-based combination antiretroviral therapy. Antimicrobial Agents and Chemotherapy. doi:10.1128/AAC.01902-19

Kula, A., Delacourt, N., Bouchat, S., DARCIS, G., Avettand-Fenoel, V., Verdikt, R., Corazza, F., Necsoi, C., Vanhulle, C., Benmoudou, M., Burny, A., de Wit, S., Rouzioux, C., Rohr, O., & Van Lint, C. (2019). Heterogeneous HIV-1 reactivation patterns of disulfiram and combined disulfiram+romidepsin treatments. Journal of Acquired Immune Deficiency Syndromes. doi:10.1097/QAI.0000000000001958

Moreno, S., Perno, C., Mallon, P., Berhens, G., Corbeau, P., Routy, J., & DARCIS, G. (2019). Two-drug vs. three-drug combinations for HIV-1: Do we have enough data to make the switch? HIV Medicine. doi:10.1111/hiv.12716

Pirotte, B., FRIPPIAT, F., DARCIS, G., Rassenfosse, M., Fombellida, K., MAES, N., Moerman, F., & MOUTSCHEN, M. (2019). Etude des motifs d'admission au service des Urgences d'une cohorte de patients. Revue Médicale de Liège.

Van Montfort, T., Van der sluis, R., DARCIS, G., Beaty, D., Groen, K., Pasternak, A., Pollakis, G., Vink, M., Westerhout, E., Hamdi, M., Bakker, M., Van Der Putten, B., Jurriaans, S., Prins, J., Jeeninga, R., Thomas, A., Speijer, D., & Berkhout, B. (2019). Dendritic cells potently purge latent HIV-1 beyond TCR-stimulation, activating the PI3K-Akt-mTOR pathway. EBioMedicine. doi:10.1016/j.ebiom.2019.02.014

DARCIS, G., Lambert, I., SAUVAGE, A.-S., FRIPPIAT, F., MEURIS, C., UURLINGS, F., LECOMTE, M., LEONARD, P., GIOT, J.-B., fombellida, K., VAIRA, D., & MOUTSCHEN, M. (2018). Factors associated with late presentation for HIV care in a single Belgian reference center: 2006-2017. Scientific Reports. doi:10.1038/s41598-018-26852-0

DARCIS, G. (2018). 2 drug combinations: unanswered questions HIV reservoirs [Paper presentation]. GILEAD symposium, Berlin, Germany.

DARCIS, G., & Berkhout, B. (2018). Human Immunodeficiency Virus Resistance to Dolutegravir: Are We Looking in the Wrong Place? Journal of Infectious Diseases. doi:10.1093/infdis/jiy474

DARCIS, G., Das, A. T., & Berkhout, B. (2018). Tackling HIV Persistence: Pharmacological versus CRISPR-Based Shock Strategies. Viruses. doi:10.3390/v10040157

DARCIS, G., & Moutschen, M. (2018). Wild-type HIV infection despite PrEP: a lot to learn from a case report. The Lancet HIV, 5 (1), 10. doi:10.1016/S2352-3018(17)30212-6

DARCIS, G., Van Driessche, B., Bouchat, S., Kirchhoff, F., & Van Lint, C. (2018). Molecular Control of HIV and SIV Latency. Current Topics in Microbiology and Immunology. doi:10.1007/82_2017_74

Khoury, G.* , Darcis, G.* , Lee, M., Bouchat, S., Van Driessche, B., Purcell, D. F.* , & Van Lint, C.*. (2018). The Molecular Biology of HIV Latency. Advances in Experimental Medicine and Biology. doi:10.1007/978-981-13-0484-2_8

DE VOEGHT, A., Martens, H., RENARD, J. D. C., VAIRA, D., Debruche, M., Simonet, J., Geenen, V., MOUTSCHEN, M., & DARCIS, G. (2017). Exploring the link between innate immune activation and thymic function by measuring sCD14 and TRECs in HIV patients living in Belgium. PLoS ONE. doi:10.1371/journal.pone.0185761

DARCIS, G., Van der Auwera, G., GIOT, J.-B., Hayette, M.-P., Tassin, F., Arrese Estrada, J., Cnops, L., Moutschen, M., de Leval, L., & LEONARD, P. (07 July 2017). Recurrence of visceral and muco-cutaneous leishmaniasis in a patient under immunosuppressive therapy. BMC Infectious Diseases, 17. doi:10.1186/s12879-017-2571-x

Bouchat, S., Verdikt, R., Delacourt, N., Vanhulle, C., Van Driessche, B., DARCIS, G., Pasternak, A., Avettand-Fenoel, V., Ledouce, V., Bendoumou, M., Schwartz, C., De Wit, S., Berkhout, B., Gautier, V., Rouzioux, C., Rohr, O., & Van Lint, C. (2017). Identification of a new factor involved in DNA methylation-mediated repression of latent HIV-1. Journal of the International AIDS Society.

DARCIS, G., Bouchat, S., Kula, A., Van Driessche, B., Delacourt, N., Vanhulle, C., Avettand-Fenoel, V., De Wit, S., Rohr, O., Rouzioux, C., & Van Lint, C. (2017). Reactivation capacity by latency-reversing agents ex vivo correlates with the size of the HIV-1 reservoir. AIDS, 31 (2), 181-189. doi:10.1097/QAD.0000000000001290

DARCIS, G., & Moutschen, M. (2017). The effect of treatment simplification on HIV reservoirs. The Lancet HIV, 4 (8), 328-e329. doi:10.1016/S2352-3018(17)30135-2

DARCIS, G., & Moutschen, M. (2017). Guérir l'infection par le VIH: Un objectif réaliste? Revue Médicale de Liège, 72 (9), 388-392.

DARCIS, G., Van Driessche, B., & Van Lint, C. (2017). HIV Latency: Should We Shock or Lock? Trends in Immunology, 38 (3), 217-228. doi:10.1016/j.it.2016.12.003

Gama, L., Abreu, C., Shirk, E., Price, S., Li, M., Laird, G., Pate, K., Wietgrefe, S., O'Connor, S., Pianowski, L., Haase, A., Van Lint, C., Siliciano, R., Clements, J., Queen, S., Bullock, B., Croteau, J., Pianowski, L., Gellerup, D., ... Mankowski, J. (2017). Reactivation of simian immunodeficiency virus reservoirs in the brain of virally suppressed macaques. AIDS. doi:10.1097/QAD.0000000000001267

Gunter, J., Callens, S., De Wit, S., Goffard, J.-C., Moutschen, M., DARCIS, G., MEURIS, C., van den Bulcke, C., Fombellida, K., del Forge, M., Razavi, H., & Wyndham-Thomas, C. (2017). Prevalence of non-infectious comorbidities in the HIV-positive population in Belgium: a multicenter, retrospective study. Acta Clinica Belgica, 1-4. doi:10.1080/17843286.2017.1339965

DARCIS, G., Hayette, M.-P., BONTEMS, S., SAUVAGE, A.-S., MEURIS, C., Van Esbroeck, M., & LEONARD, P. (March 2016). Louse-borne relapsing fever in a refugee from Somalia arriving in Belgium. Journal of Travel Medicine, 23 (3). doi:10.1093/jtm/taw009

Bouchat, S., Delacourt, N., Kula, A., DARCIS, G., Van Driessche, B., Corazza, F., GATOT, J.-S., Melard, A., Vanhulle, C., Kabeya, K., Pardons, M., Avettand-Fenoel, V., Clumeck, N., De Wit, S., Rohr, O., Rouzioux, C., & Van Lint, C. (2016). Sequential treatment with 5-aza-2'-deoxycytidine and deacetylase inhibitors reactivates HIV-1. EMBO Molecular Medicine. doi:10.15252/emmm.201505557

DARCIS, G., Bouchat, S., Kula, A., Van Driessche, B., Delacourt, N., Vanhulle, C., De Wit, S., Rohr, O., Rouzioux, C., & Van Lint, C. (2016). Reactivation capacity by latency reversing agents ex vivo correlates with the size of the HIV-1 reservoir. International Journal on Advances in Life Sciences.

DARCIS, G., Bouchat, S., Kula, A., Van Driessche, B., Delacourt, N., Vanhulle, C., De Wit, S., Rohr, O., Rouzioux, C., & Van Lint, C. (2016). Reactivation capacity by latency reversing agents ex vivo correlates with the size [Paper presentation]. 1st EU4HIVCURE symposium in University College Dublin.

DARCIS, G., Coombs, R. W., & Van Lint, C. (2016). Exploring the anatomical HIV reservoirs: Role of the testicular tissue. AIDS, 30 (18), 2891-2893. doi:10.1097/QAD.0000000000001281

DARCIS, G., Van Driessche, B., & Van Lint, C. (2016). Preclinical shock strategies to reactivate latent HIV-1: An update. Current Opinion in HIV and AIDS, 11 (4), 388-393. doi:10.1097/COH.0000000000000288

SAUVAGE, A.-S., DARCIS, G., & Moutschen, M. (2016). Actualité thérapeutique dans le VIH: Le ténofovir alafénamide. Revue Médicale Suisse, 12 (527), 1367-1369.

DARCIS, G., Kula, A., Bouchat, S., Fujinaga, K., Corazza, F., Ait-Ammar, A., Delacourt, N., Melard, A., Kabeya, K., Vanhulle, C., Van Driessche, B., GATOT, J.-S., Cherrier, T., Pianowski, L. F., Gama, L., Schwartz, C., Vila, J., Burny, A., Clumeck, N., ... Van Lint, C. (2015). An In-Depth Comparison of Latency-Reversing Agent Combinations in Various In Vitro and Ex Vivo HIV-1 Latency Models Identified Bryostatin-1+JQ1 and Ingenol-B+JQ1 to Potently Reactivate Viral Gene Expression. PLoS Pathogens, 11 (7), 1005063. doi:10.1371/journal.ppat.1005063

Kumar, A.* , DARCIS, G.* , Van Lint, C., & Herbein, G. (2015). Epigenetic control of HIV-1 post integration latency: Implications for therapy. Clinical Epigenetics, 7 (1). doi:10.1186/s13148-015-0137-6

DARCIS, G., Kula, A., Bouchat, S., Kabeya, K., Delacourt, N., Vanhulle, C., GATOT, J.-S., VAIRA, D., Burny, A., Clumeck, N., Rohr, O., MOUTSCHEN, M., Corrazza, F., Rouzioux, C., De Wit, S., & Van Lint, C. (2014). Synergistic activation of HIV-1 expression by compounds targeting the positive transcription elongation factor b (P-TEFb) and by inducers of the NF-kB signaling pathway [Paper presentation]. 20th AIDS international conference, Melbourne, Australia.

DARCIS, G., Kula, A., Bouchat, S., Kabeya, K., Delacourt, N., Vanhulle, C., GATOT, J.-S., VAIRA, D., Burny, A., Herbein, G., Clumeck, N., Rohr, O., MOUTSCHEN, M., Rouzioux, C., De Wit, S., & Van Lint, C. (2013). Synergistic activation of HIV-1 expression by compounds targeting the positive transcription elongation factor b (P-TEFb) and by inducers of the NF-B signaling pathway [Paper presentation]. First annual meeting Belgian Society for Virology.

DARCIS, G., Kula, A., Bouchat, S., Kabeya, K., Delacourt, N., Vanhulle, C., GATOT, J.-S., VAIRA, D., Burny, A., Herbein, G., Clumeck, N., Rohr, O., MOUTSCHEN, M., Rouzioux, C., De Wit, S., & Van Lint, C. (2013). Synergistic activation of HIV-1 expression by compounds targeting the positive transcription elongation factor b (P-TEFb) and by inducers of the NF-B signaling pathway [Paper presentation]. 14th European AIDS Conference (EACS), Brussels.

Witvrouw, N., Darcis, G., Gaudray, G., Schaaf-Lafontaine, N., Hustinx, R., Meuris, C., Schepers, K., & Moutschen, M. (2009). A 14-day treatment with a cyclooxygenase 2 (COX-2) inhibitor reduces inflammation in the lymphoid tissues of HIV-infected patients without HAART - a pilot study with positron emission tomography (PET/CT) assessment [Paper presentation]. International AIDS Society 2009 Cape Town, South Africa, Cape Town, South Africa.