Publications and communications of Jo Caers

Chari, A., Minnema, M. C., Berdeja, J. G., Oriol, A., van de Donk, N. W. C. J., Rodríguez-Otero, P., Askari, E., Mateos, M.-V., Costa, L. J., Caers, J., Verona, R., Girgis, S., Yang, S., Goldsmith, R. B., Yao, X., Pillarisetti, K., Hilder, B. W., Russell, J., Goldberg, J. D., & Krishnan, A. (15 December 2022). Talquetamab, a T-Cell-Redirecting GPRC5D Bispecific Antibody for Multiple Myeloma. New England Journal of Medicine, 387 (24), 2232-2244. doi:10.1056/NEJMoa2204591

Terpos, E., Zambello, R., Leleu, X., Kuehr, T., Badelita, S. N., Katodritou, E., Brescianini, A., Liang, T., Wetten, S., & Caers, J. (28 October 2022). Real-World Use and Effectiveness of Carfilzomib Plus Dexamethasone in Relapsed/Refractory Multiple Myeloma in Europe. Cancers, 14 (21). doi:10.3390/cancers14215311

Davies, F. E., Pawlyn, C., Usmani, S. Z., San-Miguel, J. F., Einsele, H., Boyle, E. M., Corre, J., Auclair, D., Cho, H. J., Lonial, S., Sonneveld, P., Stewart, A. K., Bergsagel, P. L., Kaiser, M. F., Weisel, K., Keats, J. J., Mikhael, J. R., Morgan, K. E., Ghobrial, I. M., ... Morgan, G. J. (06 July 2022). Perspectives on the Risk-Stratified Treatment of Multiple Myeloma. Blood Cancer Discovery, 3 (4), 273-284. doi:10.1158/2643-3230.BCD-21-0205

Kegyes, D.* , Constantinescu, C.* , Vrancken, L., Rasche, L., Grégoire, C., Tigu, B., Gulei, D., Dima, D., Tanase, A., Einsele, H., Ciurea, S., Tomuleasa, C., & Caers, J. (07 June 2022). Patient selection for CAR T or BiTE therapy in multiple myeloma: Which treatment for each patient? Journal of Hematology and Oncology, 15 (1), 78. doi:10.1186/s13045-022-01296-2
* These authors have contributed equally to this work.

Roussel, M., Lauwers-Cances, V., Macro, M., Leleu, X., Royer, B., Hulin, C., Karlin, L., Perrot, A., Touzeau, C., Chrétien, M.-L., Rigaudeau, S., Dib, M., Nicolas-Virelizier, E., Escoffre-Barbe, M., Belhadj, K., Mariette, C., Stoppa, A.-M., Araujo, C., Doyen, C., ... Attal, M. (05 May 2022). Bortezomib and high-dose melphalan conditioning regimen in frontline multiple myeloma: an IFM randomized phase 3 study. Blood, 139 (18), 2747-2757. doi:10.1182/blood.2021014635

Baron, F., Caers, J., & Humblet-Baron, S. (May 2022). Serological response to SARS-CoV-2 mRNA-LNP vaccine in patients with multiple myeloma: a negative impact of CD38(+) Treg? British Journal of Haematology, 197 (4), 391-393. doi:10.1111/bjh.18110

Bladé, J., Beksac, M., Caers, J., Jurczyszyn, A., von Lilienfeld-Toal, M., Moreau, P., Rasche, L., Rosiñol, L., Usmani, S. Z., Zamagni, E., & Richardson, P. (21 March 2022). Extramedullary disease in multiple myeloma: a systematic literature review. Blood Cancer Journal, 12 (3), 45. doi:10.1038/s41408-022-00643-3

Gou, M.-J., COBRAIVILLE, G., CAERS, J., & Fillet, M. (02 February 2022). Optimization of OPM-2 cell surface protein isolation process for multiple myeloma proteomics using LC-Chip coupled with IM-QTOF. Poster session presented at 4th CIRM Day, Liege, Belgium.

Gou, M.-J., COBRAIVILLE, G., CAERS, J., & Fillet, M. (12 July 2021). Multiple myeloma cells surface proteome analysis using LC-Chip coupled with IM-qTOF: optimization of cell surface protein isolation procedure. Poster session presented at 37th International Symposium on Microscale Separation and Bioanalysis, Boston, United States.

Bolomsky, A., Miettinen, J. J., Malyutina, A., Besse, A., Huber, J., Fellinger, S., Breid, H., Parsons, A., Klavins, K., Hannich, J. T., Kubicek, S., Caers, J., Hübl, W., Schreder, M., Zojer, N., Driessen, C., Tang, J., Besse, L., Heckman, C. A., & Ludwig, H. (2021). Heterogeneous modulation of Bcl-2 family members and drug efflux mediate MCL-1 inhibitor resistance in multiple myeloma. Blood Advances, 5 (20), 4125-4139. doi:10.1182/bloodadvances.2020003826

Courtois, J., Ritacco, C., DUBOIS, S., Canti, L., Vandenhove, B., SEIDEL, L., Daulne, C., CAERS, J., SERVAIS, S., Beguin, Y., Ehx, G., & BARON, F. (2021). Itacitinib prevents xenogeneic GVHD in humanized mice. Bone Marrow Transplantation, 56, 2672-2681. doi:10.1038/s41409-021-01363-1

Duray, E., Lejeune, M., Baron, F., Beguin, Y., Devoogdt, N., Krasniqi, A., Lauwers, Y., Zhao, Y. J., D'Huyvetter, M., Dumoulin, M., & Caers, J. (2021). A non-internalised CD38-binding radiolabelled single-domain antibody fragment to monitor and treat multiple myeloma. Journal of hematology & oncology, 14 (1), 183. doi:10.1186/s13045-021-01171-6

Fernández de Larrea, C., Kyle, R., Rosiñol, L., Paiva, B., Engelhardt, M., Usmani, S., Caers, J., Gonsalves, W., Schjesvold, F., Merlini, G., Lentzch, S., Ocio, E., Garderet, L., Moreau, P., Sonneveld, P., Badros, A., Gahrton, G., Goldschmidt, H., Tuchman, S., ... Mateos, M. V. (2021). Primary plasma cell leukemia: consensus definition by the International Myeloma Working Group according to peripheral blood plasma cell percentage. Blood Cancer Journal, 11 (12), 192. doi:10.1038/s41408-021-00587-0

Gamper, E. M., Cottone, F., Sommer, K., Norman, R., King, M., Breccia, M., Caocci, G., Patriarca, A., Palumbo, G. A., Stauder, R., Niscola, P., Platzbecker, U., Caers, J., Vignetti, M., & Efficace, F. (2021). The EORTC QLU-C10D was more efficient in detecting clinical known group differences in myelodysplastic syndromes than the EQ-5D-3L. Journal of Clinical Epidemiology, 137, 31-44. doi:10.1016/j.jclinepi.2021.03.015

Lejeune, M., Duray, E., Peipp, M., Clémenceau, B., Baron, F., Beguin, Y., & Caers, J. (2021). Balancing the CD38 Expression on Effector and Target Cells in Daratumumab-Mediated NK Cell ADCC against Multiple Myeloma. Cancers, 13 (12), 3072. doi:10.3390/cancers13123072

Ludwig, H., Boccadoro, M., Moreau, P., San-Miguel, J., Cavo, M., Pawlyn, C., Zweegman, S., Facon, T., Driessen, C., Hajek, R., Dimopoulos, M. A., Gay, F., Avet-Loiseau, H., Terpos, E., Zojer, N., Mohty, M., Mateos, M.-V., Einsele, H., Delforge, M., ... Sonneveld, P. (2021). Recommendations for vaccination in multiple myeloma: a consensus of the European Myeloma Network. Leukemia, 35, 31-44. doi:10.1038/s41375-020-01016-0

Ludwig, H., Sonneveld, P., Facon, T., San-Miguel, J., Avet-Loiseau, H., Mohty, M., Mateos, M.-V., Moreau, P., Cavo, M., Pawlyn, C., Zweegman, S., Engelhardt, M., Driessen, C., Cook, G., Dimopoulos, M. A., Gay, F., Einsele, H., Delforge, M., Caers, J., ... Terpos, E. (2021). COVID-19 vaccination in patients with multiple myeloma: a consensus of the European Myeloma Network. Lancet. Haematology, 8, 934-e946. doi:10.1016/S2352-3026(21)00278-7

Musto, P., Engelhardt, M., Caers, J., Bolli, N., Kaiser, M., Van de Donk, N., Terpos, E., Broijl, A., De Larrea, C. F., Gay, F., Goldschmidt, H., Hajek, R., Vangsted, A. J., Zamagni, E., Zweegman, S., Cavo, M., Dimopoulos, M., Einsele, H., Ludwig, H., ... Miguel, J. S. (2021). 2021 European Myeloma Network review and consensus statement on smoldering multiple myeloma: how to distinguish (and manage) Dr. Jekyll and Mr. Hyde. Haematologica, 106 (11), 2799-2812. doi:10.3324/haematol.2021.278519

RADERMECKER, A., BONNET, C., LUTTERI, L., CHAPELLE, A.-C., PETIGNOT, S., LIEVENS, I., & CAERS, J. (2021). Un cas illustratif de syndrome de POEMS. Revue Médicale de Liège, 76, 156-159.

Rosiñol, L., Beksac, M., Zamagni, E., Van de Donk, N. W. C. J., Anderson, K. C., Badros, A., Caers, J., Cavo, M., Dimopoulos, M.-A., Dispenzieri, A., Einsele, H., Engelhardt, M., Fernández de Larrea, C., Gahrton, G., Gay, F., Hájek, R., Hungria, V., Jurczyszyn, A., Kröger, N., ... Bladé, J. (2021). Expert review on soft-tissue plasmacytomas in multiple myeloma: definition, disease assessment and treatment considerations. British Journal of Haematology, 194 (3), 496-507. doi:10.1111/bjh.17338

Vrancken, L., Lejeune, M., PIROTTE, M., Duray, E., Köse, M. C., BEGUIN, Y., & CAERS, J. (2021). Le myélome multiple : un tour d’horizon des nouveautés dans sa biologie et son traitement. Revue Médicale de Liège, 76, 482-488.

Gou, M.-J., Nys, G., COBRAIVILLE, G., Demelenne, A., Servais, A.-C., CAERS, J., & Fillet, M. (30 September 2020). CE-MS/MS: investigation of two hyphenating approaches for proteomics studies in the context of multiple myeloma. Paper presented at 36th International Symposium on Microscale Separations and Bioanalysis, Saint-Malo, France.

Gou, M.-J., Nys, G., COBRAIVILLE, G., Demelenne, A., Servais, A.-C., Caers, J., & Fillet, M. (September 2020). Capillary electrophoresis tandem mass spectrometry for proteomics in the context of multiple myeloma: investigation of two hyphenating approaches. Paper presented at 36th International Symposium on Microscale Separations and Bioanalysis.

CAERS, J., Duray, E., Dumoulin, M., & D’Huyvetter, M. (15 May 2020). ANTI-CD38 SINGLE-DOMAIN ANTIBODIES IN DISEASE MONITORING AND TREATMENT.

Lejeune, M., Köse, M. C., Duray, E., Einsele, H., Beguin, Y., & Caers, J. (07 May 2020). Bispecific, T-Cell-Recruiting Antibodies in B-Cell Malignancies. Frontiers in Immunology, 11 (762), 1-20. doi:10.3389/fimmu.2020.00762

Bolomsky, A., Muller, J., Stangelberger, K., Lejeune, M., Duray, E., Breid, H., Vrancken, L., Pfeiffer, C., Hübl, W., Willheim, M., Weetall, M., Branstrom, A., Zojer, N., Caers, J., & Ludwig, H. (2020). The anti-mitotic agents PTC-028 and PTC596 display potent activity in pre-clinical models of multiple myeloma but challenge the role of BMI-1 as an essential tumour gene. British Journal of Haematology, 190, 877-890. doi:10.1111/bjh.16595

Bolomsky, A., Vogler, M., Köse, M. C., Heckman, C. A., Ehx, G., Ludwig, H., & Caers, J. (2020). MCL-1 inhibitors, fast-lane development of a new class of anti-cancer agents. Journal of hematology & oncology, 13 (1), 173. doi:10.1186/s13045-020-01007-9

Caers, J. (2020). The Road to a Cure: Emerging Treatments for Multiple Myeloma. Cancers, 12, 3593. doi:10.3390/cancers12123593

Caers, J. (2020). Mass cytometry in POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes) syndrome: looking for a needle in a haystack. British Journal of Haematology, 190, 16-17. doi:10.1111/bjh.16554

Caocci, G., Vignetti, M., Patriarca, A., Breccia, M., Platzbecker, U., Palumbo, G. A., Stauder, R., Cottone, F., Petranovic, D., Voso, M. T., Tafuri, A., Invernizzi, R., Caers, J., Luppi, M., La Nasa, G., Niscola, P., & Efficace, F. (2020). High serum ferritin levels in newly diagnosed patients with myelodysplastic syndromes are associated with greater symptom severity. International Journal of Hematology, 112, 141-146. doi:10.1007/s12185-020-02920-y

Efficace, F., Cottone, F., Oswald, L. B., Cella, D., Patriarca, A., Niscola, P., Breccia, M., Platzbecker, U., Palumbo, G. A., Caocci, G., Stauder, R., Ricco, A., Petranovic, D., Caers, J., Luppi, M., Fianchi, L., Frairia, C., Capodanno, I., Follini, E., ... Vignetti, M. (2020). The IPSS-R more accurately captures fatigue severity of newly diagnosed patients with myelodysplastic syndromes compared with the IPSS index. Leukemia, 34, 2451-2459. doi:10.1038/s41375-020-0746-8

Gamberi, B., Berthou, C., Hernandez, M., Semenzato, G., Tholouli, E., Hájek, R., Caers, J., Dimopoulos, M., Minnema, M. C., Andreasson, B., Parreira, J., Crotty, G., Remes, K., Kueenburg, E., Rosettani, B., Di Micco, A., Peters, S., Bacon, P., & Blau, I. W. (2020). A Noninterventional, Observational, European Post-Authorization Safety Study of Patients With Relapsed/Refractory Multiple Myeloma Treated With Lenalidomide. Clinical Lymphoma, Myeloma and Leukemia, 20, 629-e644. doi:10.1016/j.clml.2020.05.006

Lejeune, M., Köse, M. C., Duray, E., Beguin, Y., & CAERS, J. (2020). Les anticorps bispécifiques ciblant les lymphocytes T dans le myélome multiple. Onco: Revue Multidisciplinaire d'Oncologie, 14 (6), 30-34.

Vande Catsyne, C.-A., Sayyed, S. A., Molina Ortiz, P., Moës, B., Communi, D., Muller, J., Heusschen, R., CAERS, J., Azzi, A., Erneux, C., & Schurmans, S. (2020). Altered chondrocyte differentiation, matrix mineralization and MEK-Erk1/2 signaling in an INPPL1 catalytic knock-out mouse model of opsismodysplasia. Advances in Biological Regulation, 76, 100651. doi:10.1016/j.jbior.2019.100651

Vekemans, M.-C., Doyen, C., Caers, J., Wu, K., Kentos, A., Mineur, P., Michaux, L., Delforge, M., & Meuleman, N. (2020). Recommendations on the management of multiple myeloma in 2020. Acta Clinica Belgica, 1-17. doi:10.1080/17843286.2020.1860411

Bringhen, S., Milan, A., D'Agostino, M., Ferri, C., Wasch, R., Gay, F., Larocca, A., Offidani, M., Zweegman, S., Terpos, E., Goldschmidt, H., Cavo, M., Ludwig, H., Driessen, C., Auner, H., Caers, J., Gramatzki, M., Dimopoulos, M. A., Boccadoro, M., ... Engelhardt, M. (2019). Prevention, monitoring and treatment of cardiovascular adverse events in myeloma patients receiving carfilzomib A Consensus Paper by the European Myeloma Network and the Italian Society of Arterial Hypertension. Journal of Internal Medicine, 286, 63-74. doi:10.1111/joim.12882

Muller, J., Duray, E., Lejeune, M., DUBOIS, S., Plougonven, E., Léonard, A., Storti, P., Giuliani, N., Cohen-Solal, M., Hempel, U., Thijssen, V., BEGUIN, Y., Heusschen, R., & CAERS, J. (2019). Loss of stromal galectin-1 enhances multiple myeloma development: Emphasis on a role in osteoclasts. Cancers, 11 (2), 261. doi:10.3390/cancers11020261

Nokin, M.-J., Bellier, J., Durieux, F., Peulen, O., Rademaker, G., Gabriel, M., Monseur, C., CHARLOTEAUX, B., Verbeke, L., van Laere, S., RONCARATI, P., Herfs, M., Lambert, C., Scheijen, J., Schalkwijk, C., Colige, A., Caers, J., Delvenne, P., Turtoi, A., ... Bellahcene, A. (2019). Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer. Breast Cancer Research, 21(1, 11. doi:10.1186/s13058-018-1095-7

WITHOFS, N., Beguin, Y., COUSIN, F., Tancredi, T., SIMONI, P., Alvarez-Miezentseva, V., DE PRIJCK, B., HAFRAOUI, K., Bonnet, C., Baron, F., Hustinx, R., & Caers, J. (2019). Dual-tracer PET/CT scan after injection of combined [ 18 F]NaF and [ 18 F]FDG outperforms MRI in the detection of myeloma lesions. Hematological Oncology, 37, 193-201. doi:10.1002/hon.2600

Bakker, J., Balthazart, J., Baron, F., Beguin, Y., Bettendorff, L., Blanpain, C., Bureau, F., Caers, J., Cani, P., Cataldo, D., Cornil, C., Clercx, C., Cloots, R., Colige, A., Daube, G., De Backer, O., de Kerchove d'Exaerde, A., Desmecht, D., Desmet, C., ... Wittamer, V. (2018). La souris, le patient, et le faux expert. Décryptage d'une mystification. Le Vif. L'Express.

Bolomsky, A., Heusschen, R., Schlangen, K., Stangelberger, K., Muller, J., Schreiner, W., Zojer, N., Caers, J., & Ludwig, H. (2018). Maternal embryonic leucine zipper kinase is a novel target for proliferation associated high-risk myeloma. Haematologica, 103, 325-335. doi:10.3324/haematol.2017.172973

Caers, J., Garderet, L., Kortum, K. M., O'Dwyer, M. E., van de Donk, N. W. C. J., Binder, M., Dold, S. M., Gay, F., Corre, J., Beguin, Y., Ludwig, H., Larocca, A., Driessen, C., Dimopoulos, M. A., Boccadoro, M., Gramatzki, M., Zweegman, S., Einsele, H., Cavo, M., ... Engelhardt, M. (2018). European Myeloma Network recommendations on tools for the diagnosis and monitoring of multiple myeloma: what to use and when. Haematologica, 103, 1172-1184. doi:10.3324/haematol.2018.189159

Caers, J., Paiva, B., Zamagni, E., Leleu, X., Blade, J., Kristinsson, S. Y., Touzeau, C., Abildgaard, N., Terpos, E., Ocio, E., Delforge, M., Sezer, O., Beksac, M., Ludwig, H., Merlini, G., Zweegman, S., Engelhardt, M., & Rosinol, L. (2018). Diagnosis, treatment, and response assessment in solitary plasmacytoma: updated recommendations from a European Expert Panel. Journal of Hematology and Oncology, 11 (1), 10. doi:10.1186/s13045-017-0549-1

Faict, S., Muller, J., De Veirman, K., De Bruyne, E., Maes, K., Vrancken, L., Heusschen, R., De Raeve, H., Schots, R., Vanderkerken, K., Caers, J., & Menu, E. (2018). Exosomes play a role in multiple myeloma bone disease and tumor development by targeting osteoclasts and osteoblasts. Blood Cancer Journal, 8 (11), 105. doi:10.1038/s41408-018-0139-7

Fank, H., Caers, J., Marot, L., De Montjoye, L., Tennstedt, D., Baeck, M., & Dekeuleneer, V. (2018). Schnitzler syndrome associated with hairy cell leukemia presenting with chronic urticaria and arthralgias. JAAD Case Reports, 4 (4), 386-389. doi:10.1016/j.jdcr.2017.12.012

Fostier, K., & CAERS, J. (2018). Diagnosis and monitoring of multiple myeloma patients. Belgian Journal of Hematology, 9, 8-11.

Fostier, K., Caers, J., Meuleman, N., Broos, K., Corthals, J., Thielemans, K., Schots, R., & De Keersmaecker, B. (2018). Impact of lenalidomide maintenance on the immune environment of multiple myeloma patients with low tumor burden after autologous stem cell transplantation. Oncotarget, 9 (29), 20476-20489. doi:10.18632/oncotarget.24944

Gavriatopoulou, M., Musto, P., Caers, J., Merlini, G., Kastritis, E., van de Donk, N., Gay, F., Hegenbart, U., Hajek, R., Zweegman, S., Bruno, B., Straka, C., Dimopoulos, M. A., Einsele, H., Boccadoro, M., Sonneveld, P., Engelhardt, M., & Terpos, E. (2018). European myeloma network recommendations on diagnosis and management of patients with rare plasma cell dyscrasias. Leukemia, 32 (9), 1883-1898. doi:10.1038/s41375-018-0209-7

Gay, F., Engelhardt, M., Terpos, E., Wasch, R., Giaccone, L., Auner, H. W., Caers, J., Gramatzki, M., van de Donk, N., Oliva, S., Zamagni, E., Garderet, L., Straka, C., Hajek, R., Ludwig, H., Einsele, H., Dimopoulos, M., Boccadoro, M., Kroger, N., ... Sonneveld, P. (2018). From transplant to novel cellular therapies in multiple myeloma: EMN guidelines and future perspectives. Haematologica, 103, 197-211. doi:10.3324/haematol.2017.174573

Heusschen, R., Muller, J., Duray, E., WITHOFS, N., Bolomsky, A., Baron, F., Beguin, Y., Menu, E., Ludwig, H., & Caers, J. (2018). Molecular mechanisms, current management and next generation therapy in myeloma bone disease. Leukemia and Lymphoma, 59, 14-28. doi:10.1080/10428194.2017.1323272

Larocca, A., Dold, S. M., Zweegman, S., Terpos, E., Wasch, R., D'Agostino, M., Scheubeck, S., Goldschmidt, H., Gay, F., Cavo, M., Ludwig, H., Straka, C., Bringhen, S., Auner, H. W., Caers, J., Gramatzki, M., Offidani, M., Dimopoulos, M. A., Einsele, H., ... Engelhardt, M. (2018). Patient-centered practice in elderly myeloma patients: an overview and consensus from the European Myeloma Network (EMN). Leukemia, 32, 1697-1712. doi:10.1038/s41375-018-0142-9

Ludwig, H., Delforge, M., Facon, T., Einsele, H., Gay, F., Moreau, P., Avet-Loiseau, H., Boccadoro, M., Hajek, R., Mohty, M., Cavo, M., Dimopoulos, M. A., San-Miguel, J. F., Terpos, E., Zweegman, S., Garderet, L., Mateos, M.-V., Cook, G., Leleu, X., ... Sonneveld, P. (2018). Prevention and management of adverse events of novel agents in multiple myeloma: a consensus of the European Myeloma Network. Leukemia, 32, 1542-1560. doi:10.1038/s41375-018-0040-1

Muller, J., Bolomsky, A., Dubois, S., Duray, E., Stangelberger, K., Plougonven, E., Lejeune, M., Léonard, A., Marty, C., Hempel, U., Baron, F., BEGUIN, Y., Cohen-Solal, M., Ludwig, H., Heusschen, R., & CAERS, J. (2018). Maternal embryonic leucine zipper kinase inhibitor OTSSP167 has preclinical activity on multiple myeloma bone disease. Haematologica, 103, 1359-1368. doi:10.3324/haematol.2017.185397

Vercruyssen, M., Vrancken, L., & CAERS, J. (2018). What is new in MGUS and smoldering multiple myeloma. Belgian Journal of Hematology, 9, 2-7.

Vrancken, L., Muller, J., Lejeune, M., Grégoire, C., Delens, L., Jaspers, A., Servais, S., DE PRIJCK, B., Baron, F., Caers, J., & Beguin, Y. (2018). Nouveautes dans la prise en charge du myelome. Revue Médicale Suisse, 14 (615), 1438-1442.

Amorim, C., Andris, F., Arckens, L., Arnould, T., Aron, S., Bakker, J., Balligand, M., Balthazart, J., Baron, F., Beck, B., Beguin, Y., Behets, C., Bellefroid, E., Bertrand, L., Bettendorff, L., Bindels, L., Blankert, B., Blanpain, C., Bondue, A., ... Wittamer, V. (2017). L’expérimentation animale reste indispensable (OPINION). La Libre Belgique.

Heusschen, R., Bolomsky, A., Schlangen, K., Schonfelder, K., Muller, J., Shreiner, W., Zojer, N., CAERS, J., & Ludwig, H. (February 2017). Maternal Embryonic Leucine Zipper Kinase (MELK) Drives a High-Risk Gene Network and Represents an attractive Novel Drug Target in Multiple Myeloma and its associated Bone Disease. Paper presented at 32nd General Annual Meeting of the Belgian Hematological Society.

Heusschen, R., Muller, J., Bolomsky, A., Ludwig, H., & CAERS, J. (2017). Maternal Embryonic Leucine Zipper Kinase (MELK) is a key player and an attractive novel target in proliferation-associated high risk multiple myeloma. Paper presented at Meeting of the Austrian Society for Hematology and Oncology 2017.

Heusschen, R., Muller, J., Bolomsky, A., Schonfelder, K., Plougonven, E., Léonard, A., BEGUIN, Y., Cohen-Solal, M., Heinz, L., & CAERS, J. (2017). Maternal Embryonic Leucine Zipper Kinase (MELK) inhibition has direct effects on bone cells and prevents the development of osteolytic bone disease in multiple myeloma. Paper presented at 44th Annual European Calcified Tissue Society Congress.

Heusschen, R., Muller, J., WITHOFS, N., BARON, F., BEGUIN, Y., & CAERS, J. (2017). Multiple myeloma bone disease: from mechanisms to next generation therapy. Belgian Journal of Hematology, 8, 66-74.

Hillengass, J., Moulopoulos, L. A., Delorme, S., Koutoulidis, V., Mosebach, J., Hielscher, T., Drake, M., Rajkumar, S. V., Oestergaard, B., Abildgaard, N., Hinge, M., Plesner, T., Suehara, Y., Matsue, K., Waage, A., Goldschmidt, H., Dimopoulos, M. A., Lentzsch, S., Durie, B., ... CAERS, J. (2017). Whole-body computed tomography versus conventional skeletal survey in patients with multiple myeloma: a study of the International Myeloma Working Group. Blood Cancer Journal, 7 (8), 599. doi:10.1038/bcj.2017.78

Muller, J., BINSFELD, M., DUBOIS, S., Carmeliet, G., BEGUIN, Y., Heusschen, R., & CAERS, J. (2017). Galectin-1 decreases during osteoclast formation. Poster session presented at 44th Annual European Calcified Tissue Society Congress, Austria.

Sticca, T., CABERG, J.-H., Wenric, S., Poulet, C., HERENS, C., JAMAR, M., Josse, C., El Guendi, S., MAX, S., BEGUIN, Y., GOTHOT, A., CAERS, J., & Bours, V. (2017). Genomic Studies of Multiple Myeloma Reveal an Association between X Chromosome Alterations and Genomic Profile Complexity. Genes, Chromosomes and Cancer, 56, 18-27. doi:10.1002/gcc.22397

Vekemans, M.-C., Beel, K., CAERS, J., Meuleman, N., Bries, G., Demuynck, H., DE PRIJCK, B., De Samblanx, H., Deweweirea, A., Fostier, K., Mineur, P., Vaes, M., Vande Broeck, I., Vande Velde, A., Van Droogenbroeck, J., Vlummers, P., Wu, K.-L., Schots, R., Delforge, M., & Doyen, C. (2017). Update on therapy of relapsed and refractory multiple myeloma. Belgian Journal of Hematology, 8, 53-65.

Wenric, S.* , Sticca, T.* , CABERG, J.-H., Josse, C., Fasquelle, C., HERENS, C., JAMAR, M., MAX, S., GOTHOT, A., CAERS, J., & Bours, V. (2017). Exome copy number variation detection: Use of a pool of unrelated healthy tissue as reference sample. Genetic Epidemiology, 41, 35-40. doi:10.1002/gepi.22019
* These authors have contributed equally to this work.

WITHOFS, N., COUSIN, F., DE PRIJCK, B., Bonnet, C., Hustinx, R., Gambhir, S. S., Beguin, Y., & Caers, J. (2017). A First Report on [(18)F]FPRGD2 PET/CT Imaging in Multiple Myeloma. Contrast Media and Molecular Imaging, 2017, 6162845. doi:10.1155/2017/6162845

SID, S., Baron, F., WILLEMS, E., Caers, J., Bonnet, C., DE PRIJCK, B., LEJEUNE, M., HAFRAOUI, K., Servais, S., JASPERS, A., & Beguin, Y. (November 2016). Hematologic recovery after autologus stem cell transplantation in multiple myeloma: a single center experience of 225 patients. Paper presented at 16ème Congrès commun de la SFGM-TC & 8ème de la SFBCT, Liège, Belgium.

Jurczyszyn, A., Olszewska-Szopa, M., Hungria, V., Crusoe, E., Pika, T., Delforge, M., Leleu, X., Rasche, L., Nooka, A., Druzd-Sitek, A., Walewski, J., Davila, J., CAERS, J., Maisnar, V., Gertz, M., Gentile, M., Fantl, D., Mele, G., Vesole, D., ... Castillo, J. (September 2016). Cutaneous involvement in multiple myeloma: a multi-institutional retrospective study of 53 patients. Leukemia and Lymphoma, 57 (9 2071-6), 2071-6. doi:10.3109/10428194.2015.1128542

Fransolet, G.* , Ehx, G.* , SOMJA, J., Delens, L., Hannon, M., Muller, J., DUBOIS, S., Drion, P., CAERS, J., Humblet-Baron, S., DELVENNE, P., BEGUIN, Y., Conteduca, G.* , & BARON, F.*. (04 July 2016). Azacytidine mitigates experimental sclerodermic chronic graft-versus-host disease. Journal of Hematology and Oncology, 9, 53. doi:10.1186/s13045-016-0281-2
* These authors have contributed equally to this work.

WITHOFS, N., COUSIN, F., TANCREDI, T., SIMONI, P., DE PRIJCK, B., HAFRAOUI, K., BONNET, C., HUSTINX, R., BEGUIN, Y., & CAERS, J. (14 June 2016). Comparison of combined whole-body 18F-NAF and 18F-FDG PET/CT versus MRI for the detection of myeloma lesions. Paper presented at SNMMI 2016 Annual Meeting.

Laubach, J., Garderet, L., Mahindra, A., Gahrton, G., CAERS, J., Sezer, O., Voorhees, P., Leleu, X., Johnsen, H., Streetly, M., Ludwig, H., Mellqvist, U., Chng, W., Pilarski, L., Einsele, H., Hou, J., Turesson, I., Zamagni, E., Chim, J., ... Richardson, P. (30 May 2016). Management of relapsed multiple myeloma: Recommendations of the international myeloma working group. Leukemia, 30 (5), 1005-1017. doi:10.1038/leu.2015.356

Muller, J., Binsfeld, M., DUBOIS, S., Carmeliet, G., BEGUIN, Y., Heusschen, R., & CAERS, J. (28 February 2016). Galectin-1 is involved in osteoclast biology. Poster session presented at 2nd Herbert Fleisch Workshop, Brugge, Belgium.

Fransolet, G., Ehx, G., SOMJA, J., Delens, L., Hannon, M., DUBOIS, S., Drion, P., CAERS, J., Humblet-Baron, S., Belle, L., DELVENNE, P., BEGUIN, Y., Conteduca, G., & Baron, F. (29 January 2016). Azacytidine and Decitabine prevent experimental sclerodermic chronic graft-versus-host disease. Poster session presented at 31st general annual meeting of the Belgian Hematological Society, La Hulpe, Belgium.

Binsfeld, M., Muller, J., Lamour, V., De Veirman, K., De Raeve, H., Bellahcene, A., Van Valckenborgh, E., BARON, F., BEGUIN, Y., CAERS, J., & Heusschen, R. (2016). Granulocytic myeloid-derived suppressor cells promote angiogenesis in the context of multiple myeloma. Oncotarget, 7, 37931-37943. doi:10.18632/oncotarget.9270

Bolomsky, A., Heusschen, R., Schlangen, K., Schönfelder, K., Muller, J., Schreiner, W., Zojer, N., CAERS, J., & Ludwig, H. (2016). Maternal Embryonic Leucine Zipper Kinase (MELK) Drives a High-Risk Gene Network and Represents an attractive Novel Drug Target in Multiple Myeloma. Blood.

CAERS, J., de Larrea, C., Leleu, X., Heusschen, R., Zojer, N., Decaux, O., Kastritis, E., Minnema, M., Jurczyszyn, A., Beguin, Y., Wäsch, R., Palumbo, A., Dimopoulos, M., Mateos, M. V., Ludwig, H., & Engelhardt, M. (2016). The Changing Landscape of Smoldering Multiple Myeloma: A European Perspective. Oncologist, 21, 333-342. doi:10.1634/theoncologist.2015-0303

Heusschen, R., Muller, J., BEGUIN, Y., Poirier, F., Cohen-Solal, M., Thijssen, V., & CAERS, J. (2016). Galectin-1 attenuates bone resorption by osteoclasts. Poster session presented at EMBO Workshop: Transducing glycan information into function: Lessons from galectins.

Heusschen, R.* , Muller, J.* , Binsfeld, M., Marty, C., Plougonven, E., DUBOIS, S., Mahli, N., Moermans, K., Carmeliet, G., Léonard, A., BARON, F., BEGUIN, Y., Menu, E., Cohen-Solal, M., & CAERS, J. (2016). SRC Kinase Inhibition with Saracatinib Limits the Development of Osteolytic Bone Disease in Multiple Myeloma. Oncotarget, 7, 30712-30729. doi:10.18632/oncotarget.8750
* These authors have contributed equally to this work.

Heusschen, R., Muller, J., Binsfeld, M., Marty, C., Plougonven, E., DUBOIS, S., Mahli, N., Moermans, K., Carmeliet, G., Léonard, A., BARON, F., Cohen-Solal, M., Vanderkerken, K., BEGUIN, Y., Menu, E., & CAERS, J. (2016). SRC kinase inhibition with saracatinib limits the development of osteolytic bone disease in multiple myeloma. Belgian Journal of Hematology.

Heusschen, R., Muller, J., Binsfeld, M., Marty, C., Plougonven, E., DUBOIS, S., Mahli, N., Moermans, K., Carmeliet, G., Léonard, A., BARON, F., Cohen-Solal, M., Vanderkerken, K., BEGUIN, Y., Menu, E., & CAERS, J. (2016). SRC kinase inhibition with saracatinib limits the development of osteolytic bone disease in multiple myeloma. Paper presented at 31st General Annual Meeting of the Belgian Hematological Society, Brussels, Belgium.

Heusschen, R., Muller, J., Binsfeld, M., Plougonven, E., Mahli, N., Carmeliet, G., Léonard, A., Cohen-Solal, M., Vanderkerken, K., BEGUIN, Y., Menu, E., & CAERS, J. (2016). The Src Inhibitor AZD0530 Prevents the Development of Osteolytic Bone Disease in Multiple Myeloma. Poster session presented at 43rd Annual European Calcified Tissue Society Congress, Rome, Italy.

Heusschen, R., Muller, J., Binsfeld, M., Plougonven, E., Mahli, N., Carmeliet, G., Léonard, A., Cohen-Solal, M., Vanderkerken, K., BEGUIN, Y., Menu, E., & CAERS, J. (2016). SRC Kinase Inhibition with Saracatinib Limits the Development of Osteolytic Bone Disease in Multiple Myeloma. Poster session presented at GIGA day 2016, Liège, Belgium.

Heusschen, R., Muller, J., Fillet, M., Vanderkerken, K., Thijssen, V., Cohen-Solal, M., BEGUIN, Y., & CAERS, J. (2016). Lectin-glycoprotein interactions in the diagnosis and biology of myeloma-related bone disease. Poster session presented at 2nd Herbert Fleisch Workshop of the International Bone and Mineral Society, Brugge, Belgium.

Jurczyszyn, A., Grzasko, N., Gozzetti, A., Czepiel, J., Cerase, A., Hungria, V., Crusoe, E., Silva Dias, A. L. M., Vij, R., Fiala, M. A., CAERS, J., Rasche, L., Nooka, A. K., Lonial, S., Vesole, D. H., Philip, S., Gangatharan, S., Druzd-Sitek, A., Walewski, J., ... Castillo, J. J. (2016). Central nervous system involvement by multiple myeloma: A multi-institutional retrospective study of 172 patients in daily clinical practice. American Journal of Hematology, 91 (6), 575-80. doi:10.1002/ajh.24351

Muller, J., Binsfeld, M., DUBOIS, S., Carmeliet, G., BEGUIN, Y., Heusschen, R., & CAERS, J. (2016). Galectin-1 is involved in osteoclast biology. Poster session presented at 43rd Annual European Calcified Tissue Society Congress, Rome, Italy.

Sonneveld, P., Avet-Loiseau, H., Lonial, S., Usmani, S., Siegel, D., Anderson, K., Chng, W.-J., Moreau, P., Attal, M., Kyle, R., CAERS, J., Hillengass, J., San Miguel, J., van de Donk, N., Einsele, H., Bladé, J., Durie, B., Goldschmidt, H., Mateos, M.-V., ... Orlowski, R. (2016). Treatment of Multiple Myeloma with high-risk cytogenetics: a consensus of the International Myeloma Working Group. Blood, 127 (24), 2955-62. doi:10.1182/blood-2016-01-631200

Fransolet, G., Ehx, G., SOMJA, J., Hannon, M., DUBOIS, S., Drion, P., CAERS, J., Humblet-Baron, S., Belle, L., Delvenne, P., BEGUIN, Y., Conteduca, G., & Baron, F. (19 November 2015). L'Azacytidine comme traitement de la maladie du greffon contre l'hôte de type chronique sclérodermique expérimentale. Paper presented at 15ème congrès de la Société Française de Greffe de Moelle et de Thérapie Cellulaire, Clermont-Ferrand, France.

WITHOFS, N., NANNI, C., SIMONI, P., FANTI, S., BEGUIN, Y., & CAERS, J. (20 March 2015). Imaging myeloma and related monoclonal plasma cell disorders using MRI, low dose whole-body CT and FDG PET/CT. Clinical and Translational Imaging, 3, 95-109. doi:10.1007/s40336-015-0119-x

BINSFELD, M., Hannon, M., Humblet-Baron, S., Beguin, Y., Baron, F., & CAERS, J. (30 January 2015). Effects of the immunomodulating peptide thymosin alpha 1 in multiple myeloma and immune reconstitution after hematopoietic stem cell transplantation in murine models. Poster session presented at 30th General Annual Meeting of the Belgian Hematology Society, La Hulpe, Belgium.

Binsfeld, M., HANNON, M., Otjacques, E., Humblet-Baron, S., BAUDOUX, E., BEGUIN, Y., BARON, F., & CAERS, J. (2015). Impact of the immunomodulating peptide thymosin alpha 1 on multiple myeloma and immune recovery after hematopoietic stem cell transplantation. Cancer Immunology, Immunotherapy, 64, 989-998. doi:10.1007/s00262-015-1708-2

Heusschen, R., Muller, J., Binsfeld, M., Plougonven, E., Mahli, N., Carmeliet, G., Léonard, A., Cohen-Solal, M., Vanderkerken, K., BEGUIN, Y., Menu, E., & CAERS, J. (2015). The SRC inhibitor AZD0530 prevents the development of osteolytic bone disease in multiple myeloma. Blood.

Heusschen, R., Muller, J., Binsfeld, M., Plougonven, E., Mahli, N., Carmeliet, G., Léonard, A., Cohen-Solal, M., Vanderkerken, K., BEGUIN, Y., Menu, E., & CAERS, J. (2015). The SRC inhibitor AZD0530 prevents the development of osteolytic bone disease in multiple myeloma. Blood, 126 (23), 3018.

Heusschen, R., Muller, J., Binsfeld, M., Plougonven, E., Mahli, N., Carmeliet, G., Léonard, A., Cohen-Solal, M., Vanderkerken, K., BEGUIN, Y., Menu, E., & CAERS, J. (2015). The SRC inhibitor AZD0530 prevents the development of osteolytic bone disease in multiple myeloma. Poster session presented at 57th ASH Annual Meeting and Exposition, Orlando, United States - Florida.

Muller, J., Binsfeld, M., DUBOIS, S., Carmeliet, G., Beguin, Y., Heusschen, R., & CAERS, J. (2015). The anti-angiogenic peptide Anginex blocks osteoclastogenesis. Belgian Journal of Hematology, Abstracts book.

Sticca, T., Wenric, S., CABERG, J.-H., MAX, S., GOTHOT, A., CAERS, J., & Bours, V. (2015). Genomic study of multiple myeloma based on SNP-aCGH and high-throughput exome sequencing.

Tangen, J.-M., Tierens, A., CAERS, J., BINSFELD, M., Olstad, O. K., Troseid, A.-M. S., Wang, J., Tjonnfjord, G. E., & Hetland, G. (January 2015). Immunomodulatory Effects of the Agaricus blazei Murrill-Based Mushroom Extract AndoSan in Patients with Multiple Myeloma Undergoing High Dose Chemotherapy and Autologous Stem Cell Transplantation: A Randomized, Double Blinded Clinical Study. BioMed Research International, 2015, 718539. doi:10.1155/2015/718539

Thijssen, V., Heusschen, R., CAERS, J., & Griffioen, A. (2015). Galectin expression in cancer diagnosis and prognosis: a systematic review. Biochimica et Biophysica Acta - Reviews on Cancer, 1855 (2), 235-47. doi:10.1016/j.bbcan.2015.03.003

CAERS, J., WITHOFS, N., Hillengass, J., SIMONI, P., Zamagni, E., HUSTINX, R., & BEGUIN, Y. (April 2014). The role of positron emission tomography-computed tomography and magnetic resonance imaging in diagnosis and follow-up of multiple myeloma. Haematologica, 99 (4), 629-37. doi:10.3324/haematol.2013.091918

CAERS, J., HAFRAOUI, K., KEUTGENS, A., CABERG, J.-H., LAMBERT, F., TASSIN, F., & BEGUIN, Y. (02 February 2014). Haematological and molecular responses in refractory anaemia with ring sideroblasts and thrombocytosis treated with lenalidomide. European Journal of Haematology, 92 (2), 179-180. doi:10.1111/ejh.12233

Binsfeld, M., BEGUIN, Y., Belle, L., Otjacques, E., HANNON, M., BRIQUET, A., Drion, P., Bogen, B., Baron, F., & CAERS, J. (2014). Establishment of a murine graft-versus-myeloma model using allogeneic stem cell transplantation. Belgian Journal of Hematology.

Binsfeld, M., Beguin, Y., Belle, L., Otjacques, E., HANNON, M., BRIQUET, A., Heusschen, R., Drion, P., Zilberberg, J., Bogen, B., Baron, F., & CAERS, J. (2014). Establishment of a murine graft-versus-myeloma model using allogeneic stem cell transplantation. PLoS ONE, 113764. doi:10.1371/journal.pone.0113764

Binsfeld, M., Fostier, K., Muller, J., Baron, F., Schots, R., Beguin, Y., Heusschen, R., & CAERS, J. (2014). Cellular immunotherapy in multiple myeloma : lessons from preclinical models. Biochimica et Biophysica Acta - Reviews on Cancer, 1846, 392-404. doi:10.1016/j.bbcan.2014.08.001

Binsfeld, M., Heusschen, R., Lamour, V., Van Valckenborgh, E., Bellahcene, A., Baron, F., BEGUIN, Y., & CAERS, J. (2014). Multiple myeloma cells instruct myeloid-derived suppressor cells to release pro-angiogenic cytokines. Belgian Journal of Hematology.

CAERS, J., & BEGUIN, Y. (2014). Le myélome multiple asymptomatique : le paysage thérapeutique change. Oncol. Hematol, 8, 39-45.

CAERS, J., Binsfeld, M., Muller, J., Heusschen, R., & Beguin, Y. (2014). Gammapathie monoclonale de signification indéterminée : information destinée aux médecins référents. Revue Médicale de Liège, 69, 41-46.

Heusschen, R., Muller, J., Binsfeld, M., Thijssen, V., BEGUIN, Y., & CAERS, J. (2014). Galectin expression in the multiple myeloma microenvironment. Poster session presented at GIGA day 2014, Liège, Belgium.

Heusschen, R., Schulkens, I., Muller, J., Griffioen, A., BEGUIN, Y., Thijssen, V., & CAERS, J. (2014). Galectins in cancer: jacks of all trades. Paper presented at 19th World Congress on Advances in Oncology, Athens, Greece.

Heusschen, R., Schulkens, I., Muller, J., Griffoen, A., Beguin, Y., Thijssen, V., & CAERS, J. (2014). Galectins in cancer: jacks of all trades. International Journal of Molecular Medicine.

Muller, J., CAERS, J., Binsfeld, M., Dubois, S., Carmeliet, G., BEGUIN, Y., & Heusschen, R. (2014). Galectin expression in the multiple myeloma microenvironment. Belgian Journal of Hematology.

Rajkumar, V., Dimopoulos, M., Palumbo, A., Blade, J., Merlini, G., Mateos, M.-V., Kumar, S., Hillengass, J., Kastritis, E., Richardson, P., Landgren, O., Paiva, B., Dispenzieri, A., Weiss, B., Leleu, X., Zweegman, S., Lonial, S., Rosinol, L., Zamagni, E., ... San Miguel, J. (2014). International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma. Lancet Oncology, 538-548. doi:10.1016/S1470-2045(14)70442-5

Belle, L., Ehx, G., SOMJA, J., Binsfeld, M., HANNON, M., CAERS, J., Fransolet, G., BEGUIN, Y., Humblet-Baron, S., & Baron, F. (December 2013). Combination Of Regulatory T Cells and Rapamycin As Treatment For Experimental Chronic Graft-Versus-Host Disease. Poster session presented at 55th Annual Meeting of the American Society of Hematology.

Belle, L., Ehx, G., SOMJA, J., BINSFELD, M., Hannon, M., Caers, J., Fransolet, G., Beguin, Y., Humblet-Baron, S., & Baron, F. (December 2013). Combination Of Regulatory T Cells and Rapamycin As Treatment For Experimental Chronic Graft-Versus-Host Disease. Blood, 122 (21), 4474.

CAERS, J., Vekemans, M.-C., Bries, G., Beel, K., Delrieu, V., Deweweire, A., Demuynck, H., DE PRIJCK, B., De Samblanx, H., Kentos, A., Meuleman, N., Mineur, P., Offner, F., Vande Broek, I., Van Droogenbroeck, J., Vande Velde, A., Wu, K.-L., Delforge, M., Schots, R., & Doyen, C. (September 2013). Diagnosis and follow-up of monoclonal gammopathies of undetermined significance; information for referring physicians. Annals of Medicine, 45, 413-422. doi:10.3109/07853890.2013.801562

Binsfeld, M., BEGUIN, Y., Belle, L., Otjacques, E., HANNON, M., BRIQUET, A., Drion, P., Bogen, B., BARON, F., & CAERS, J. (April 2013). Establishment of a murine graft-versus-myeloma model using allogeneic stem cell transplantation. Poster session presented at 3rd International Conference "Cancer Immunotherapy and Immunomonitoring (CITIM)", Cracovie, Poland.

Fernández de Larrea, C., Kyle, R., Durie, B., Ludwig, H., Usmani, S., Vesole, D., Hajek, R., San Miguel, J., Sezer, O., Schots, R., Sonneveld, P., Kumar, S., Mahindra, A., Comenzo, R., Palumbo, A., Anderson, K., Richardson, P., Badros, A., CAERS, J., ... Shah, J. (April 2013). Plasma cell leukemia: consensus statement on diagnostic requirements, response criteria and treatment recommendations by the International Myeloma Working Group. Leukemia, 27 (4), 780-91. doi:10.1038/leu.2012.336

Belle, L., BINSFELD, M., DUBOIS, S., Hannon, M., Caers, J., BRIQUET, A., MENTEN, C., BEGUIN, Y., Humblet-Baron, S., & Baron, F. (February 2013). Prevention of murine sclerodermatous chronic graft-versus-host disease by Rapamycin. Biology of Blood and Marrow Transplantation, 19, 317.

JASPERS, A., CAERS, J., LE GAC, G., FEREC, C., BEGUIN, Y., & FILLET, G. (February 2013). A novel mutation in the CUB sequence of matriptase-2 (TMPRSS6) is implicated in iron-resistant iron deficiency anaemia (IRIDA). British Journal of Haematology, 160 (4), 564-565. doi:10.1111/bjh.12147

Bonnet, C., MENTEN, C., LAMBERT, F., Gothot, A., Baron, F., CAERS, J., HERENS, C., & Beguin, Y. (25 January 2013). Simultaneous diagnosis of CLL and CML in a single patient with evidence for two different cell clones. Poster session presented at BHS, General Annual Meeting.

Belle, L., Binsfeld, M., Dubois, S., Hannon, M., CAERS, J., BRIQUET, A., MENTEN, C., BEGUIN, Y., Humblet-Baron, S., & BARON, F. (2013). Prevention of murine sclerodermatous chronic graft-versus-host disease by Rapamycin. Poster session presented at BMT Tandem Meetings (ASBMT), Salt Lake City, United States.

Belle, L., Binsfeld, M., HANNON, M., CAERS, J., BRIQUET, A., MENTEN, C., BEGUIN, Y., Humblet-Baron, S., & Baron, F. (2013). Combination of Regulatory T Cells Injection with Rapamycin for Treatment of Chronic Graft-versus-Host Disease. Belgian Journal of Hematology.

Belle, L., Binsfeld, M., Hannon, M., CAERS, J., BRIQUET, A., MENTEN, C., Beguin, Y., Humblet-Baron, S., & BARON, F. (2013). Combination of Regulatory T Cells Injection with Rapamycin for Treatment of Chronic Graft-versus-Host Disease. Paper presented at 28th General Meeting of the Belgian Hematological Society.

Binsfeld, M., Otjacques, E., Hannon, M., DUBOIS, S., Beguin, Y., Baron, F., & CAERS, J. (2013). The Immunomodulating Peptide Thymosin Alpha 1 Has no Effect on Multiple Myeloma Evolution and on Immune Reconstitution. Belgian Journal of Hematology, Abstracts book (Supplement of 28th General Meeting of the Belgian Hematological Society), 41.

Cornet, G., GRAYET, B., Godon, A., & CAERS, J. (January 2013). Image of the month: Hairy kidneys. Revue Médicale de Liège, 68 (1), 4-5.

DE PASQUAL, A., BIESSAUX, Y., Blettard, N., CREMERS, S., & CAERS, J. (2013). Unexplained cardiac failure leading to the identification of a Belgian family affected by hereditary amyloidosis. Acta Clinica Belgica, 68 (4), 303-305. doi:10.2143/ACB.3268

HAFRAOUI, K., CAERS, J., TASSIN, F., & Beguin, Y. (2013). Hematological and molecular responses in a case of refractory anemia with ring sideroblasts and thrombocytosis (RARS-T) treated by Lenalidomide. Poster session presented at BHS 28th General Annual Meeting, Gent, Belgium.

Haroche, J., Arnaud, L., Cohen-Aubart, F., Hervier, B., Saadoun, D., Costedoat-Chalumeau, N., Besnard, S., Heang Ly, K., Pavic, M., Fuzibet, J.-G., Raffray, L., Aaron, L., Bindi, P., Marinho, A., Blomberg, B., Salvatierra, J., Dechant, C., Rigolet, A., Lifermann, F., ... Amoura, Z. (2013). Erdheim-Chester Disease : A Monocentric Series Of 96 Patients. Poster session presented at 2013 ACR/ARHP Annual Meeting.

Otjacques, E., Binsfeld, M., Beguin, Y., Noël, A., Cataldo, D., & CAERS, J. (2013). Aspects biologiques de l'angiogenèse dans le myélome multiple. Oncohématologie, 7 (2), 6-12.

Otjacques, E., Binsfeld, M., Rocks, N., Blacher, S., Vanderkerken, K., Noël, A., Beguin, Y., Cataldo, D., & CAERS, J. (2013). Mithramycin Exerts an Anti-Myeloma Effect and Displays Anti-Angiogenic Effects through Up-Regulation of Anti-Angiogenic Factors. PLoS ONE, 8 (5), 62818. doi:10.1371/journal.pone.0062818

SIMONI, P., STULKO, J., BEN MUSTAPHA, S., SCHOYSMAN, L., BIANCHI, E., WITHOFS, N., RACARU, T., CAERS, J., & ALVAREZ MIEZENTSEVA, V. (2013). Bone mass of the calvarium. Skeletal Radiology, 42, 1185-1187. doi:10.1007/s00256-012-1547-6

Vekemans, M.-C., CAERS, J., Doyen, C., & Michaux, L. (2013). Gammapathies monoclonales de signification indéterminée. Louvain Medical, 132 (2), 51-62.

Belle, L., BINSFELD, M., Dubois, S., Hannon, M., CAERS, J., BRIQUET, A., MENTEN, C., Beguin, Y., Humbelt-Baron, S., & BARON, F. (April 2012). Rapamycin prevents experimental sclerodermatous chronic graft-versus-host disease in mice. Bone Marrow Transplantation, 47 Suppl 1.

Belle, L., Binsfeld, M., DUBOIS, S., Hannon, M., CAERS, J., Briquet, A., MENTEN, C., Beguin, Y., Humblet-Baron, S., & Baron, F. (2012). Rapamycin prevents experimental sclerodermatous chronic graft-versus-host disease in mice. Paper presented at 38th EBMT Annual Meeting.

Belle, L., Binsfeld, M., DUBOIS, S., Hannon, M., CAERS, J., BRIQUET, A., MENTEN, C., Beguin, Y., Humblet-Baron, S., & Baron, F. (2012). Rapamycin Prevents Experimental Sclerodermatous Chronic Graft-versus-Host Disease in mice. Paper presented at 27th General Meeting of the Belgian Hematological Society.

Binsfeld, M., Belle, L., Hannon, M., DUBOIS, S., Otjacques, E., Beguin, Y., Baron, F., & CAERS, J. (2012). Adaptation of a Murine Chronic GVH Model to Study Graft versus Myeloma Effect after Allogeneic Transplantation. Belgian Journal of Hematology, Abstracts book (Supplement of 27th General Meeting of the Belgian Hematological Society), 16.

Binsfeld, M., Belle, L., Hannon, M., Hofgaard, Dubois, S., Otjacques, E., BEGUIN, Y., Bogen, BARON, F., & CAERS, J. (2012). Adaptation of a murine chronic GvH model to study graftversus- myeloma effect after allogeneic transplantation. Bone Marrow Transplantation, 47 (Suppl.1).

Gamberi, B., Kyriakou, C., Ashcroft, J., Hernandez, M., CAERS, J., Bos, G., Echeveste, M. A., Berthou, C., Zambello, R., Kuenburg, E., Rosettani, B., Ryder-Smith, B., & Blau, I. (2012). Overall Safety and Treatment Duration in Lenalidomide (LEN)-, Thalidomide (THAL)-, and Bortezomib (BORT)-Treated Patients within the European Post-Approval Safety Study (EU PASS) of Relapsed/Refractory Multiple Myeloma (RRMM). Poster session presented at 54th ASH Annual Meeting.

Hofgaard, P., Jodal, H., Bommert, K., Huard, B., CAERS, J., Carlsen, H., Schwarzer, R., Schunemann, Jundt, F., Lindeberg, M., & Bogen, B. (2012). A novel mouse model for multiple myeloma (MOPC315.BM) that allows noninvasive spatiotemporal detection of osteolytic disease. PLoS ONE, 7 (12), 51892. doi:10.1371/journal.pone.0051892

Malaise, O., FRUSCH, N., BECK, E., Servais, S., BETEA, D., CAERS, J., DE PRIJCK, B., & BEGUIN, Y. (2012). Panhypopituitarism and diabetus insipidus in a patient with primary central nervous system lymphoma. Leukemia and Lymphoma, 53 (12), 2515-16.

Bonnet, C., CAERS, J., DE PRIJCK, B., HAFRAOUI, K., & Beguin, Y. (2011). Lymphome du manteau : prise en charge 2011. Revue Médicale Suisse, 7, 1644-1649.

CAERS, J., BONNET, C., GRAUX, C., DE PRIJCK, B., & BEGUIN, Y. (2011). Prise en charge actuelle des syndromes myélodysplasiques. Revue Médicale Suisse, 7, 1634-1643.

Otjacques, E., Binsfeld, M., Noël, A., Beguin, Y., Cataldo, D., & CAERS, J. (2011). Biological aspects of angiogenesis in multiple myeloma. International Journal of Hematology, 94 (6), 505-18. doi:10.1007/s12185-011-0963-z

Bieghs, L., Caers, J., De Bruyne, E., Van Valckenborgh, E., Hibbinbotham, F., Vanderkerken, K., & Menu, E. (2010). The effects of forodesine in murine and human multiple myeloma cells. Advances in Hematology, 2010:131895. doi:10.1155/2010/131895

Caers, J., Hose, D., Kuijpers, I., Bos, T., Van Valckenborgh, E., Menu, E., De Bruyne, E., Goldschmidt, H., Van Camp, B., Klein, B., & Vanderkerken, K. (2010). Thymosin Beta 4 has tumor suppressive effects and its decreased expression results in poor prognosis and decreased survival in multiple myeloma. Haematologica, 95 (1), 163-167. doi:10.3324/haematol.2009.006411

Caers, J., Otjacques, E., Hose, D., Klein, B., & Vanderkerken, K. (2010). Thymosin beta4 in multiple myeloma: friend or foe. Annals of the New York Academy of Sciences, 1194 (1), 125-130. doi:10.1111/j.1749-6632.2010.05470.x

Schots, R., Delforge, M., André, M., Bries, G., CAERS, J., Demuynck, H., DE PRIJCK, B., De Samblanx, H., Kentos, A., Meuleman, N., Offner, F., Vekemans, M., Vande Broek, I., Van Droogenbroeck, J., Van de Velde, A., Wu, K., & Doyen, C. (2010). The Belgian 2010 consensus recommendations for the treatment of multiple myeloma. Acta Clinica Belgica, 65, 252-264. doi:10.1179/acb.2010.055

Segner, S., Theate, I., Poire, X., Tennstedt, D., Marot, & Caers, J. (2010). Diffuse xanthomatosis as a presenting feature of multiple myeloma. European Journal of Haematology, 84, 460-461. doi:10.1111/j.1600-0609.2009.01400.x

Servais, S., Caers, J., Warling, O., Frusch, N., Baron, F., De Prijck, B., & Beguin, Y. (2010). Enteroviral meningoencephalitis as complication of Rituximab therapy in a patient treated for diffuse large B-cell lymphoma. British Journal of Haematology, 150 (3), 379-381. doi:10.1111/j.1365-2141.2010.08202.x

Sinapi, I., Caers, J., Connerotte, T., Koutaissoff, S., & Lambert, M. (2010). Retroperitoneal fibrosis and multiple myeloma: fortuitous association? Revue de Médecine Interne, 31 (5), 4-6. doi:10.1016/j.revmed.2009.04.011

CAERS, J. (2009). New biological and therapeutical findings in the interactions between multiple myeloma cells and their microenvironment. Unpublished doctoral thesis, VUB - Vrije Universiteit Brussel.
Jury: Vanderkerken, K. (Promotor), ... Van Camp, B. (Promotor).

CAERS, J. (2009). New biological and therapeutical findings in the interactions between multiple myeloma cells and their microenvironment. Brussels, Belgium: VUBPRESS.

Caers, J., De Raeve, H., Lepage, D., Van Valckenborgh, E., Menu, E., Alvarez, E., Van Camp, B., & Vanderkerken, K. (2008). Antitumor and anti-angiogenic effects of aplidin in the 5T33MM model, syngeneic model of multiple myeloma. British Journal of Cancer, 98 (12), 1966-74. doi:10.1038/sj.bjc.6604388

CAERS, J., Hose, D., Kuipers, I., Bos, T., Van Valckenborgh, E., Menu, E., De Bruyne, E., Goldschmidt, H., Van Camp, B., Klein, B., & Vanderkerken, K. (2008). Decreased Thymosin Beta 4 Expression Results in Poor Prognosis and Decreased Survival in Multiple Myeloma. Poster session presented at 50th ASH Annual Meeting.

Caers, J., Van Valckenborgh, E., Menu, E., Van Camp, B., & Vanderkerken, K. (2008). Unraveling the biology of MM disease: cancer stem cells, acquired intracellular changes and interactions with the surrounding micro-environment. Bulletin du Cancer, 95 (3), 301-13. doi:10.1684/bdc.2008.0600

Caers, J., Vande Broek, I., De Raeve, H., Michaux, L., Trullemans, F., Schots, R., Van Camp, B., & Vanderkerken, K. (2008). Multiple Myeloma, an update on diagnosis and treatment. European Journal of Haematology, 81 (5), 329-343. doi:10.1111/j.1600-0609.2008.01127.x

Caers, J., Deleu, S., Belaid, Z., De Raeve, H., Van Valckenborgh, E., De Bruyne, E., Defresne, M.-P., Van Riet, I., Van Camp, B., & Vanderkerken, K. (July 2007). Neighboring adipocytes participate in the bone marrow microenvironment of multiple myeloma cells. Leukemia, 21 (7), 1580-1584. doi:10.1038/sj.leu.2404658

CAERS, J., DeLeu, S., Belaid, Z., De Raeve, H., Van Valckenborgh, E., De Bruyne, E., Defresne, M.-P., Van Riet, I., Van Camp, B., & Vanderkerken, K. (2007). Neighboring adipocytes participate in the bone marrow micro-environment of multiple myeloma cells. Leukemia, 21 (7), 1580-4.

Vanderkerken, K., Van Valckenborgh, E., Menu, E., De Raeve, H., Van Riet, I., Schots, R., CAERS, J., & Van Camp, B. (2007). De bijdrage van muismodellen bij studies naar multipel myeloom. Nederlands Tijdschrift voor Hematologie, 4 (4), 193-143.

CAERS, J., Belaid, Z., Deleu, S., Defresne, M.-P., & Vanderkerken, K. (2006). Bone Marrow Adipocytes Influence Multiple Myeloma Development by Secretion of Different Growth Factors and Chemokines. Poster session presented at 48th ASH Annual Meeting.

Caers, J., Günthert, U., De Raeve, H., Van Valckenborgh, E., Menu, E., Van Riet, I., Van Camp, B., & Vanderkerken, K. (2006). The involvement of osteopontin and its receptors in multiple myeloma cell survival, migration and invasion in the murine 5T33MM model. British Journal of Haematology, 132 ((4)), 469-77. doi:10.1111/j.1365-2141.2005.05886.x

Caers, J., Peeters, P., Vanden Houte, K., Van der Niepen, P., & Verbeelen, D. (2006). Acute interstitial nephritis associated with salmonellosis. European Journal of Internal Medicine, 17 (3), 217-9. doi:10.1016/j.ejim.2005.09.026

Caers, J., & Vanderkerken, K. (2006). Ac-SDKP: linking cardiac remodelling to haematological malignancies. Leukemia and Lymphoma, 47 (9), 1732-3.

De Bruyne, E., Andersen, T. L., De Raeve, H., Van Valckenborgh, E., Caers, J., Van Camp, B., Delaisse, J. M., Van Riet, I., & Vanderkerken, K. (2006). Endothelial cell-driven regulation of CD9 or motility-related protein-1 expression in multiple myeloma cells within the murine 5T33MM model and myeloma patients. Leukemia, 20 (10), 1870-9. doi:10.1038/sj.leu.2404343

Caers, J., Asosingh, K., Van Camp, B., Van Riet, I., & Vanderkerken, K. (2005). Of mice and men: disease models of multiple myeloma. Drugs Discovery Today: disease models, 1 (4), 373-380.

Caers, J., Fontaine, C., Vinh-Hung, V., De Mey, J., Ponnet, G., Oost, C., Lamote, J., De Greve, J., Van Camp, B., & Lacor, P. (2005). Catheter tip position as a risk factor for thrombosis associated with the use of subcutaneous infusion ports. Supportive Care in Cancer, 13 ((5)), 325-31. doi:10.1007/s00520-004-0723-1

CAERS, J., De Raeve, H., Asosingh, K., Van Riet, I., Van Camp, B., & Vanderkerken, K. (17 September 2004). Expression of osteopontin and its receptor the alphavbeta3 integrin in the 5TMM myeloma model. Poster session presented at Progress against tumor progression, Genoa, Italy.

Caers, J., Reekmans, A., Jochmans, K., Naegels, S., Mana, F., Urbain, D., & Reynaert, H. (2003). Factor V inhibitor after injection of human thrombin in a bleeding ulcer. Endoscopy, 35 ((6)), 542-4. doi:10.1055/s-2003-39678